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Приказ резултата 11-20 од 226
Thermal properties of 3-hydroxy fatty acids and their binary mixtures as phase change energy storage materials
(John Wiley & Sons, Ltd., 2020)
In the present work, we describe the chemical synthesis of 3-HFAs as prominent derivatives of fatty acids and assess if they could be applied as phase change materials (PCM). In addition, 3-HFAs were obtained by depolymerization ...
Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures
(Springer Verlag, 2019)
Humans are exposed to multiple chemicals on a daily basis instead of to just a single chemical, yet the majority of existing toxicity data comes from single-chemical exposure. Multiple factors must be considered such as ...
Phenolic profile, antibacterial, antimutagenic and antitumour evaluation of Veronica urticifolia Jacq.
(Elsevier Science BV, Amsterdam, 2014)
The phenolic profile and antibacterial, antimutagenic and antitumour activities of the methanolic extracts of Veronica urticifolia Jacq. were evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic acids, ...
Digital light processing (DLP) 3D printing of atomoxetine hydrochloride tablets using photoreactive suspensions
(MDPI AG, 2020)
Three-dimensional (3D) printing technologies are based on successive material printing layer-by-layer and are considered suitable for the production of dosage forms customized for a patient’s needs. In this study, tablets ...
Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle
(Elsevier B.V., 2021)
The objective of this investigation was to obtain jute fabrics with enhanced sorption properties (by using simple and cost-effective alkali and oxidative modifications) and a long life cycle. The applied alkali modifications ...
Effect of ibuprofen entrapment procedure on physicochemical and controlled drug release performances of chitosan/xanthan gum polyelectrolyte complexes
(Elsevier B.V., 2021)
The effect of the entrapment procedure of a poorly water soluble drug (ibuprofen) on physicochemical and drug release performances of chitosan/xanthan polyelectrolyte complexes (PECs) was investigated to achieve controlled ...
Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study
(Elsevier Sci Ltd, Oxford, 2019)
Background The polymorphic CYP2D6 enzyme metabolises the antipsychotic drugs risperidone and aripiprazole to their active metabolites, 9OH-risperidone and dehydroaripiprazole. The aim of this study was to quantify the ...
Quantitative structure retention relationship modeling in liquid chromatography method for separation of candesartan cilexetil and its degradation products
(Elsevier Science BV, Amsterdam, 2015)
Artificial neural network (ANN) is a learning system based on a computation technique, which was employed for building of the quantitative structure-retention relationship (QSRR) model for candesartan cilexetil and its ...
Interaction between Omeprazole and Gliclazide in Relation to CYP2C19 Phenotype
(MDPI, 2021)
The antidiabetic drug gliclazide is partly metabolized by CYP2C19, the main enzyme involved in omeprazole metabolism. The aim of the study was to explore the interaction between omeprazole and gliclazide in relation to ...
The Polymorphic Nuclear Factor NFIB Regulates Hepatic CYP2D6 Expression and Influences Risperidone Metabolism in Psychiatric Patients
(John Wiley and Sons Inc, 2022)
The genetic background for interindividual variability of the polymorphic CYP2D6 enzyme activity remains incompletely understood and the role of NFIB genetic polymorphism for this variability was evaluated in this translational ...