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Potential modulating effect of the Ascaris suum nicotinic acetylcholine receptor (nAChR) by compounds GSK575594A, diazepam and flumazenil discovered by structure-based virtual screening approach
(Elsevier B.V., 2021)
Parasitic infections are a widespread health problem and research of novel anthelmintic compounds is of the utmost importance. In this study we performed a virtual screening campaign by coupling ligand-based pharmacophore, ...
Fatty acids as biomodulators of Piezo1 mediated glial mechanosensitivity in Alzheimer's disease
(Elsevier Inc., 2022)
The brain is the softest organ in the body, and any change in the mechanical properties of the tissue induces the activation of glial cells, astrocytes and microglia. Amyloid plaques, one of the main pathological features ...
The influence of smoking habits on cadmium and lead blood levels in the Serbian adult people
(Springer-Verlag GmbH Germany, part of Springer Nature, 2020)
According to theWorld Health Organization, in 2015, the Serbian population ranked among the highest ones in Europe in terms of smoking habit: 44.3%males and 36.2%females aged 18–64 smoked tobacco. In the last 7 years, 25%of ...
Method transfer assessment for boric acid assays according to different pharmacopoeias' monographs
(Springer Nature, 2020)
The background of this study was transfer assessment for H3BO3 assays according to different pharmacopoeias’ monographs and verification of the crucial parameters—the polyols’ excess (mannitol, glycerine, sorbitol), the ...
Predicting sulforaphane-induces adverse effects in prostatic cancer patients via in silico investigation
(Elsevier, 2023)
Prostate cancer is a major cause of death in men. Traditional therapies have limited efficacy, leading to the increased interest in phytochemicals like sulforaphane (SFN), found in cruciferous vegetables. ...
Quality benchmarking of smartphone laboratory medicine applications: Comparison of laboratory medicine specialists' and non-laboratory medicine professionals' evaluation
(De Gruyter Open Ltd, 2021)
There are many mobile health applications (apps) now available and some that use in some way laboratory medicine data. Among them, patient-oriented are of the lowest content quality. The aim of this study was to compare ...
The environmental impact of potassium tungstophosphate/ZSM-5 zeolite: Insight into catalysis and adsorption processes
(Elsevier B.V., 2021)
Environmental implementation of novel composite materials comprising potassium tungstophosphate (KPW) and ZSM-5 zeolite was tested in ethene production and pesticide removal. The study revealed that the binding of KPW to ...
Evidence of acute phase reaction in asymptomatic dogs naturally infected with Babesia canis
(Elsevier, 2020)
Asymptomatic outdoor dogs can be carriers of Babesia canis, but data describing the development of an acute phase response (APR) are not available. We hypothesised that these dogs have a moderate APR that could be detected ...
Gradient Boosted Tree model: A fast track tool for predicting the Atmospheric Pressure Chemical Ionization-Mass Spectrometry signal of antipsychotics based on molecular features and experimental settings
(Elsevier B.V., 2022)
Predicting the response signal in Atmospheric Pressure Chemical Ionization - Mass Spectrometry (APCI-MS) systems appears to be considerably challenging due to a gap in knowledge of governing factors and nature of their ...
Tableting of hot-melt coated paracetamol granules: Material tableting properties and quality characteristics of the obtained tablets
(Elsevier B.V., 2020)
Hot-melt coating (HMC) has been recognized as a promising technique in the production of solid dosage forms e.g., HMC of granules can be applied prior to compression in order to obtain modified drug release or taste masking. ...