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Synthesis of the vitamin E amino acid esters with an enhanced anticancer activity and in silico screening for new antineoplastic drugs
(Elsevier Science BV, Amsterdam, 2016)
Tocopherols and tocotrienols belong to the family of vitamin E (VE) with the well-known antioxidant properties. For certain alpha-tocopherol and gamma-tocotrienol derivatives used as the lead compounds in this study, ...
Formulation of hydrogel-thickened nonionic microemulsions with enhanced percutaneous delivery of ibuprofen assessed in vivo in rats
(Elsevier Science BV, Amsterdam, 2016)
The study investigated usage of hydrogel of an anionic polymer xanthan gum for design of ibuprofen-loaded hydrogel-thickened microemulsions (HTMs) from the nonionic oil-in-water microemulsion (M). Xanthan gum demonstrated ...
Formulation and characterization of nanofibers and films with carvedilol prepared by electrospinning and solution casting method
(Elsevier Science BV, Amsterdam, 2017)
The preparation and characterization of films and nanofibers with carvedilol as a poorly water-soluble drug in poly (ethylene oxide) (PEO) polymer were investigated. Films are prepared by solution casting method, and ...
Biopartitioning micellar chromatography as a predictive tool for skin and corneal permeability of newly synthesized 17 beta-carboxamide steroids
(Elsevier Science BV, Amsterdam, 2014)
In this paper, human skin and corneal permeability of twenty-two newly synthesized 17 beta-carboxamide steroids was predicted using biopartitioning micellar chromatography (BMC). These compounds are potential soft ...
Fludized hot melt granulation: in situ vs. Spray-on procedure
(Elsevier Science BV, Amsterdam, 2011)
Characteristics of low-density and high-density lipoprotein subclasses in pediatric renal transplant recipients
(Elsevier Science BV, Amsterdam, 2011)
A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells
(Elsevier Science BV, Amsterdam, 2011)
Application of gastrointestinal simulation for development of in vitro-in vivo correlation for levothyroxine sodium immediate-release tablets
(Elsevier Science BV, Amsterdam, 2011)
Analysis of fluidized bed granulation process using conventional and novel modeling techniques
(Elsevier Science BV, Amsterdam, 2011)
Various modeling techniques have been applied to analyze fluidized-bed granulation process. Influence of various input parameters (product, inlet and outlet air temperature, consumption of liquid-binder, granulation ...
Population pharmacokinetics of topiramate in adult patients with epilepsy using nonlinear mixed effects modelling
(Elsevier Science BV, Amsterdam, 2013)
The objective of the study was to develop population pharmacokinetic model of topiramate (TPM) using nonlinear mixed effects modelling approach. Data were collected from 78 adult epileptic patients on mono- or co-therapy ...