Objective skin performance evaluation: How mild are APGs to the skin?
Само за регистроване кориснике
2014
Поглавље у монографији (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection of emulsifiers. Alkyl Polyglucoside (APG) emulsifiers, successfully used in cosmetics and popularly labelled as skin- and environmentally friendly, have attracted considerable interest. Non-invasive measurements of biophysical skin parameters, and approved in vitro methods, are used for reliable and objective determination of skin properties. This chapter discusses assessment of the performance of topical emulsions, particularly those based on APG-mixed emulsifiers, and interpretation of the results. Research into the safety and efficacy of APGs indicates that APG surfactants could be used for tailoring mild emulsion vehicles, showing benefits as carriers for actives with an unfavourable skin irritation profile.
Кључне речи:
Alkyl Polyglucoside mixed emulsifiers / Biophysical skin parameters / In vivo/in vitro skin safety and efficacy / Moisturizing cosmetic actives / Pharmaceutical and cosmetic emulsion-type topical proИзвор:
Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems, 2014, 135-161Издавач:
- Elsevier Inc.
Институција/група
PharmacyTY - CHAP AU - Tasić-Kostov, Marija AU - Vesić, Sonja AU - Savić, Snežana PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2258 AB - Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection of emulsifiers. Alkyl Polyglucoside (APG) emulsifiers, successfully used in cosmetics and popularly labelled as skin- and environmentally friendly, have attracted considerable interest. Non-invasive measurements of biophysical skin parameters, and approved in vitro methods, are used for reliable and objective determination of skin properties. This chapter discusses assessment of the performance of topical emulsions, particularly those based on APG-mixed emulsifiers, and interpretation of the results. Research into the safety and efficacy of APGs indicates that APG surfactants could be used for tailoring mild emulsion vehicles, showing benefits as carriers for actives with an unfavourable skin irritation profile. PB - Elsevier Inc. T2 - Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems T1 - Objective skin performance evaluation: How mild are APGs to the skin? SP - 135 EP - 161 DO - 10.1533/9781908818775.135 ER -
@inbook{ author = "Tasić-Kostov, Marija and Vesić, Sonja and Savić, Snežana", year = "2014", abstract = "Emulsion systems are the most common vehicles for topical drugs/cosmetic actives. Absence of skin irritation potential is an important legislative requirement. Overcoming emulsion irritancy is usually achieved by selection of emulsifiers. Alkyl Polyglucoside (APG) emulsifiers, successfully used in cosmetics and popularly labelled as skin- and environmentally friendly, have attracted considerable interest. Non-invasive measurements of biophysical skin parameters, and approved in vitro methods, are used for reliable and objective determination of skin properties. This chapter discusses assessment of the performance of topical emulsions, particularly those based on APG-mixed emulsifiers, and interpretation of the results. Research into the safety and efficacy of APGs indicates that APG surfactants could be used for tailoring mild emulsion vehicles, showing benefits as carriers for actives with an unfavourable skin irritation profile.", publisher = "Elsevier Inc.", journal = "Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems", booktitle = "Objective skin performance evaluation: How mild are APGs to the skin?", pages = "135-161", doi = "10.1533/9781908818775.135" }
Tasić-Kostov, M., Vesić, S.,& Savić, S.. (2014). Objective skin performance evaluation: How mild are APGs to the skin?. in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems Elsevier Inc.., 135-161. https://doi.org/10.1533/9781908818775.135
Tasić-Kostov M, Vesić S, Savić S. Objective skin performance evaluation: How mild are APGs to the skin?. in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems. 2014;:135-161. doi:10.1533/9781908818775.135 .
Tasić-Kostov, Marija, Vesić, Sonja, Savić, Snežana, "Objective skin performance evaluation: How mild are APGs to the skin?" in Alkyl Polyglucosides: From Natural-Origin Surfactants to Prospective Delivery Systems (2014):135-161, https://doi.org/10.1533/9781908818775.135 . .