Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement
Аутори
Đuričić, IvanaStanković, Ivan
Ivanović, Nevena
Todorović, Vanja
Timić, Jasmina
Šobajić, Slađana
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Introduction: It is well known that long-term and regular intakes
of long chain (LC) n-3 polyunsaturated fatty acids (PUFAs) from fish
or fish oil supplements are useful in improving n-3 fatty status. Dietary
guidelines recommend use of these fatty acids in purpose of cardio-
vascular primary and secondary preventions.
Objectives: The objective of this study was to explore the difference in plasma fatty acid profile following general recommendations for
fish intake or fish oil supplement usage.
Method / Design: Participants were randomised to receive
salmon (oily fish) providing 274 mg EPA + 671 mg DHA/day or commercial fish oil supplement providing 396 mg EPA + 250 mg DHA/
day in cross-over trial over 8 weeks period separated by the 6 months
washout period. Fatty acids were extracted from plasma and analysed
by gas chromatography.
Results: The initial plasma concentration of fatty acids was not
different between groups at baseline and after the washout phase. After
8 wee...ks, there was a significant increase in the level of EPA, DHA and
total n-3 fatty acids in plasma of both groups. The percentage values
of EPA increased by 135% in salmon group (p<0.0001) and 152% in
fish oil group (p<0.0001), whereas DHA increased by 145% in salmon
(p<0.0001) and 121% in fish oil group (p<0.010). The increase of plasma total n-3 fatty acids observed after 8 wks of the salmon consumption was greater when compared with fish oil (45% vs 27%) (p<0.05)
and mirrored the content in used dietary sources.
Conclusions: Plasma n-3 fatty acid profile was remarkably increased with both salmon and fish oil capsules intervention. Increase
of plasma EPA and DHA levels was dose-dependent.
Кључне речи:
plasma / n-3 fatty acids / fish / fish oil supplementsИзвор:
Annals of Nutrition and Metabolism, 2015, 67, Supplement 1, 137-137Издавач:
- Karger, Basel
Напомена:
- 12th European Nutrition Conference (FENS), Berlin, Germany, October 20-23, 2015
Институција/група
PharmacyTY - CONF AU - Đuričić, Ivana AU - Stanković, Ivan AU - Ivanović, Nevena AU - Todorović, Vanja AU - Timić, Jasmina AU - Šobajić, Slađana PY - 2015 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2339 AB - Introduction: It is well known that long-term and regular intakes of long chain (LC) n-3 polyunsaturated fatty acids (PUFAs) from fish or fish oil supplements are useful in improving n-3 fatty status. Dietary guidelines recommend use of these fatty acids in purpose of cardio- vascular primary and secondary preventions. Objectives: The objective of this study was to explore the difference in plasma fatty acid profile following general recommendations for fish intake or fish oil supplement usage. Method / Design: Participants were randomised to receive salmon (oily fish) providing 274 mg EPA + 671 mg DHA/day or commercial fish oil supplement providing 396 mg EPA + 250 mg DHA/ day in cross-over trial over 8 weeks period separated by the 6 months washout period. Fatty acids were extracted from plasma and analysed by gas chromatography. Results: The initial plasma concentration of fatty acids was not different between groups at baseline and after the washout phase. After 8 weeks, there was a significant increase in the level of EPA, DHA and total n-3 fatty acids in plasma of both groups. The percentage values of EPA increased by 135% in salmon group (p<0.0001) and 152% in fish oil group (p<0.0001), whereas DHA increased by 145% in salmon (p<0.0001) and 121% in fish oil group (p<0.010). The increase of plasma total n-3 fatty acids observed after 8 wks of the salmon consumption was greater when compared with fish oil (45% vs 27%) (p<0.05) and mirrored the content in used dietary sources. Conclusions: Plasma n-3 fatty acid profile was remarkably increased with both salmon and fish oil capsules intervention. Increase of plasma EPA and DHA levels was dose-dependent. PB - Karger, Basel C3 - Annals of Nutrition and Metabolism T1 - Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement VL - 67 IS - Supplement 1 SP - 137 EP - 137 DO - 10.1159/000440895 ER -
@conference{ author = "Đuričić, Ivana and Stanković, Ivan and Ivanović, Nevena and Todorović, Vanja and Timić, Jasmina and Šobajić, Slađana", year = "2015", abstract = "Introduction: It is well known that long-term and regular intakes of long chain (LC) n-3 polyunsaturated fatty acids (PUFAs) from fish or fish oil supplements are useful in improving n-3 fatty status. Dietary guidelines recommend use of these fatty acids in purpose of cardio- vascular primary and secondary preventions. Objectives: The objective of this study was to explore the difference in plasma fatty acid profile following general recommendations for fish intake or fish oil supplement usage. Method / Design: Participants were randomised to receive salmon (oily fish) providing 274 mg EPA + 671 mg DHA/day or commercial fish oil supplement providing 396 mg EPA + 250 mg DHA/ day in cross-over trial over 8 weeks period separated by the 6 months washout period. Fatty acids were extracted from plasma and analysed by gas chromatography. Results: The initial plasma concentration of fatty acids was not different between groups at baseline and after the washout phase. After 8 weeks, there was a significant increase in the level of EPA, DHA and total n-3 fatty acids in plasma of both groups. The percentage values of EPA increased by 135% in salmon group (p<0.0001) and 152% in fish oil group (p<0.0001), whereas DHA increased by 145% in salmon (p<0.0001) and 121% in fish oil group (p<0.010). The increase of plasma total n-3 fatty acids observed after 8 wks of the salmon consumption was greater when compared with fish oil (45% vs 27%) (p<0.05) and mirrored the content in used dietary sources. Conclusions: Plasma n-3 fatty acid profile was remarkably increased with both salmon and fish oil capsules intervention. Increase of plasma EPA and DHA levels was dose-dependent.", publisher = "Karger, Basel", journal = "Annals of Nutrition and Metabolism", title = "Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement", volume = "67", number = "Supplement 1", pages = "137-137", doi = "10.1159/000440895" }
Đuričić, I., Stanković, I., Ivanović, N., Todorović, V., Timić, J.,& Šobajić, S.. (2015). Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement. in Annals of Nutrition and Metabolism Karger, Basel., 67(Supplement 1), 137-137. https://doi.org/10.1159/000440895
Đuričić I, Stanković I, Ivanović N, Todorović V, Timić J, Šobajić S. Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement. in Annals of Nutrition and Metabolism. 2015;67(Supplement 1):137-137. doi:10.1159/000440895 .
Đuričić, Ivana, Stanković, Ivan, Ivanović, Nevena, Todorović, Vanja, Timić, Jasmina, Šobajić, Slađana, "Plasma fatty acid profile after nutritionally relevant intakes of oily fish and fish oil supplement" in Annals of Nutrition and Metabolism, 67, no. Supplement 1 (2015):137-137, https://doi.org/10.1159/000440895 . .