Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome
Само за регистроване кориснике
2017
Аутори
Petrović, MilanPetrović, Marija
Milasinović, Goran
Vujisić-Tesić, Bosiljka
Trifunović, Danijela
Petrović, Olga
Nedeljković, Ivana
Petrović, Ivana
Banović, Marko
Boricić-Kostić, Marija
Petrović, Jelena
Arena, Ross
Popović, Dejana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Aims: Selection of patients who are viable candidates for cardiac resynchronization therapy (CRT), prediction of the response to CRT as well as an optimal definition of a favorable response, all require further exploration. The purpose of this study was to evaluate the interplay between the prediction of the response to CRT and the definition of a favorable outcome. Methods: Seventy patients who received CRT were included. All patients met current guideline criteria for CRT. Forty-three echocardiographic parameters were evaluated before CRT and at 1, 3, 6, and 12 months. M-mode, 2D echocardiography, and Doppler imaging were used to quantify left ventricular (LV) systolic and diastolic function, mitral regurgitation, right ventricular systolic function, pulmonary artery pressure, and myocardial mechanical dyssynchrony. The following definitions of a favorable CRT response were used: left ventricular ejection fraction (LVEF) improvement more >5% acutely following CRT, LVEF improvement >2...0% at 12-month follow-up, and a LV end-systolic volume (LVESV) decrease >15% at 12-month follow-up. Results: For the LVEF improvement >5%, the best predictor was isovolumetric relaxation time (IVRT; P=.035). For improvement of LVEF >20%, the best predictors were left ventricular stroke index (LVSI; P=.044) and left ventricular fractional shortening (LVFS; P=.031). For the drop in left ventricular systolic volume (LVESV >15%), the best predictor was septal-to-lateral wall delay (Delta T) (P=.043, RR=1.023, 95% CI for RR=1.001-1.045). Conclusion: The definition of a favorable CRT response influenced the optimal predictor variable(s). Standardization of defining a favorable response to CRT is needed to guide clinical decision making processes.
Извор:
Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 2017, 34, 3, 371-375Издавач:
- Wiley, Hoboken
Финансирање / пројекти:
- Асимптоматска митрална регургитација, нови погледи на стари проблем (RS-MESTD-Basic Research (BR or ON)-175086)
DOI: 10.1111/echo.13453
ISSN: 0742-2822
PubMed: 28075037
WoS: 000398109300007
Scopus: 2-s2.0-85010338822
Институција/група
PharmacyTY - JOUR AU - Petrović, Milan AU - Petrović, Marija AU - Milasinović, Goran AU - Vujisić-Tesić, Bosiljka AU - Trifunović, Danijela AU - Petrović, Olga AU - Nedeljković, Ivana AU - Petrović, Ivana AU - Banović, Marko AU - Boricić-Kostić, Marija AU - Petrović, Jelena AU - Arena, Ross AU - Popović, Dejana PY - 2017 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2918 AB - Aims: Selection of patients who are viable candidates for cardiac resynchronization therapy (CRT), prediction of the response to CRT as well as an optimal definition of a favorable response, all require further exploration. The purpose of this study was to evaluate the interplay between the prediction of the response to CRT and the definition of a favorable outcome. Methods: Seventy patients who received CRT were included. All patients met current guideline criteria for CRT. Forty-three echocardiographic parameters were evaluated before CRT and at 1, 3, 6, and 12 months. M-mode, 2D echocardiography, and Doppler imaging were used to quantify left ventricular (LV) systolic and diastolic function, mitral regurgitation, right ventricular systolic function, pulmonary artery pressure, and myocardial mechanical dyssynchrony. The following definitions of a favorable CRT response were used: left ventricular ejection fraction (LVEF) improvement more >5% acutely following CRT, LVEF improvement >20% at 12-month follow-up, and a LV end-systolic volume (LVESV) decrease >15% at 12-month follow-up. Results: For the LVEF improvement >5%, the best predictor was isovolumetric relaxation time (IVRT; P=.035). For improvement of LVEF >20%, the best predictors were left ventricular stroke index (LVSI; P=.044) and left ventricular fractional shortening (LVFS; P=.031). For the drop in left ventricular systolic volume (LVESV >15%), the best predictor was septal-to-lateral wall delay (Delta T) (P=.043, RR=1.023, 95% CI for RR=1.001-1.045). Conclusion: The definition of a favorable CRT response influenced the optimal predictor variable(s). Standardization of defining a favorable response to CRT is needed to guide clinical decision making processes. PB - Wiley, Hoboken T2 - Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques T1 - Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome VL - 34 IS - 3 SP - 371 EP - 375 DO - 10.1111/echo.13453 ER -
@article{ author = "Petrović, Milan and Petrović, Marija and Milasinović, Goran and Vujisić-Tesić, Bosiljka and Trifunović, Danijela and Petrović, Olga and Nedeljković, Ivana and Petrović, Ivana and Banović, Marko and Boricić-Kostić, Marija and Petrović, Jelena and Arena, Ross and Popović, Dejana", year = "2017", abstract = "Aims: Selection of patients who are viable candidates for cardiac resynchronization therapy (CRT), prediction of the response to CRT as well as an optimal definition of a favorable response, all require further exploration. The purpose of this study was to evaluate the interplay between the prediction of the response to CRT and the definition of a favorable outcome. Methods: Seventy patients who received CRT were included. All patients met current guideline criteria for CRT. Forty-three echocardiographic parameters were evaluated before CRT and at 1, 3, 6, and 12 months. M-mode, 2D echocardiography, and Doppler imaging were used to quantify left ventricular (LV) systolic and diastolic function, mitral regurgitation, right ventricular systolic function, pulmonary artery pressure, and myocardial mechanical dyssynchrony. The following definitions of a favorable CRT response were used: left ventricular ejection fraction (LVEF) improvement more >5% acutely following CRT, LVEF improvement >20% at 12-month follow-up, and a LV end-systolic volume (LVESV) decrease >15% at 12-month follow-up. Results: For the LVEF improvement >5%, the best predictor was isovolumetric relaxation time (IVRT; P=.035). For improvement of LVEF >20%, the best predictors were left ventricular stroke index (LVSI; P=.044) and left ventricular fractional shortening (LVFS; P=.031). For the drop in left ventricular systolic volume (LVESV >15%), the best predictor was septal-to-lateral wall delay (Delta T) (P=.043, RR=1.023, 95% CI for RR=1.001-1.045). Conclusion: The definition of a favorable CRT response influenced the optimal predictor variable(s). Standardization of defining a favorable response to CRT is needed to guide clinical decision making processes.", publisher = "Wiley, Hoboken", journal = "Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques", title = "Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome", volume = "34", number = "3", pages = "371-375", doi = "10.1111/echo.13453" }
Petrović, M., Petrović, M., Milasinović, G., Vujisić-Tesić, B., Trifunović, D., Petrović, O., Nedeljković, I., Petrović, I., Banović, M., Boricić-Kostić, M., Petrović, J., Arena, R.,& Popović, D.. (2017). Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome. in Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques Wiley, Hoboken., 34(3), 371-375. https://doi.org/10.1111/echo.13453
Petrović M, Petrović M, Milasinović G, Vujisić-Tesić B, Trifunović D, Petrović O, Nedeljković I, Petrović I, Banović M, Boricić-Kostić M, Petrović J, Arena R, Popović D. Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome. in Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques. 2017;34(3):371-375. doi:10.1111/echo.13453 .
Petrović, Milan, Petrović, Marija, Milasinović, Goran, Vujisić-Tesić, Bosiljka, Trifunović, Danijela, Petrović, Olga, Nedeljković, Ivana, Petrović, Ivana, Banović, Marko, Boricić-Kostić, Marija, Petrović, Jelena, Arena, Ross, Popović, Dejana, "Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome" in Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques, 34, no. 3 (2017):371-375, https://doi.org/10.1111/echo.13453 . .
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