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Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)
dc.creator | Savić, Ivan | |
dc.creator | Nikolić, Ivana Lj. | |
dc.creator | Savić-Gajić, Ivana | |
dc.creator | Kundaković, Tatjana | |
dc.date.accessioned | 2019-09-02T12:11:41Z | |
dc.date.available | 2019-09-02T12:11:41Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0149-6395 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/3362 | |
dc.description.abstract | The aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3). | en |
dc.publisher | Taylor & Francis Inc, Philadelphia | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34012/RS// | |
dc.rights | restrictedAccess | |
dc.source | Solid State Ionics | |
dc.subject | Chickpea | en |
dc.subject | total polyphenol | en |
dc.subject | total flavonoid | en |
dc.subject | antioxidant activity | en |
dc.subject | central composite design | en |
dc.title | Modeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L) | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Савић-Гајић, Ивана; Николић, Ивана Љ.; Савић, Иван М.; Кундаковић, Татјана; | |
dc.citation.volume | 54 | |
dc.citation.issue | 5 | |
dc.citation.spage | 837 | |
dc.citation.epage | 846 | |
dc.citation.other | 54(5): 837-846 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000464574300018 | |
dc.identifier.doi | 10.1080/01496395.2018.1520720 | |
dc.identifier.scopus | 2-s2.0-85053510649 | |
dc.type.version | publishedVersion |