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Endothelium-dependent relaxations to histamine in the rat common carotid, renal and cranial mesenteric artery
dc.creator | Krstić, M.K | |
dc.creator | Stepanović-Petrović, Radica | |
dc.creator | Krstić, S.K | |
dc.creator | Katušić, Z.S | |
dc.date.accessioned | 2019-09-02T10:46:58Z | |
dc.date.available | 2019-09-02T10:46:58Z | |
dc.date.issued | 1988 | |
dc.identifier.issn | 1381-3455 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/39 | |
dc.description.abstract | The effect of histamine on the isolated rat common carotid, renal and cranial mesenteric arteries was examined. Histamine (10-8 - 10-4 m) caused concentration-dependent relaxations of the arteries during contractions induced with phenylephrine (10-8 - 10-7 m). Removal of the vascular endothelium inhibited the histamine-induced relaxations. Pyrilamine (6 × 10-6 m), but not metiamide (10-6 m), abolished the relaxant effect of histamine. Moreover, pyrilamine (6 × 10-6 m) did not affect endothelium-dependent relaxations of the arteries produced with acetylcholine. These results indicate that histamine causes endothelium-dependent relaxations of the rat peripheral large conduit arteries, which appeared to be mediated via H1-histaminergic receptors. | en |
dc.publisher | Informa Healthcare | |
dc.rights | restrictedAccess | |
dc.source | Archives of Physiology and Biochemistry | |
dc.title | Endothelium-dependent relaxations to histamine in the rat common carotid, renal and cranial mesenteric artery | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Крстић, С.К; Крстић, М.К; Степановић-Петровић, Радица; Катушић, З.С; | |
dc.citation.volume | 96 | |
dc.citation.issue | 3 | |
dc.citation.spage | 197 | |
dc.citation.epage | 200 | |
dc.citation.other | 96(3): 197-200 | |
dc.description.other | Union of the Scientific Medical Institutions of Serbia (Grant No. 231). | en |
dc.identifier.doi | 10.3109/13813458809075944 | |
dc.identifier.scopus | 2-s2.0-0024212973 | |
dc.type.version | publishedVersion |