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Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen
(MDPI, 2023)
The aim of the study was a synthesis and investigation of the dose-dependent anti-inflammatory effect of new thiourea derivatives of naproxen with selected aromatic amines and esters of aromatic amino acids. The results ...
Biocompatible nanoemulsions as a tool for preclinical testing of CW-02-79, a pyrazoloquinolinone modulator of sigma-2 receptors: preformulation and formulation studies
(4th European Conference on Pharmaceutics, 20 - 21 March 2023, Marseille, France, 2023)
INTRODUCTION
Recently, the modulation of sigma-2 receptors localized in the brain is proposed to be linked with regulation of mood, anxiety, and cognition [1]. Hence, we hypothesized that novel patent-protected ligand of ...
Searching for the best way to incorporate the proprietary compound GL-II -73 into the nanoemulsion carrier for prospective parenteral application
(International Association of Physical Chemists, 2023)
Searching for the best way to incorporate the proprietary compound GL-II -73 into the nanoemulsion carrier for prospective parenteral application
Jelena Đoković1, Bojan Marković2, Dishary Sharmin3, James M Cook3, Miroslav ...
A proposal of innovative injectability assessment method for intravenous formulations - case study on PEGylated nanoemulsions
(9th BBBB International conference on pharmaceutical sciences; 15th - 17th September, Ljubljana, Slovenia, 2022)
1. INTRODUCTION
Syringeability and injectability are recognised as fundamental performance parameters / critical quality attributes of any parenteral dosage form. Syringeability refers to the ability of an injectable ...
Freeze-dried nanocrystal dispersion of novel deuterated pyrazoloquinolinone ligand (DK-I-56-1): process parameters and cryoprotectant selection through stability study
(9th BBBB International conference on pharmaceutical sciences; 15th - 17th September, Ljubljana, Slovenia, 2022)
1. INTRODUCTION
Nanocrystal dispersions are considered as the universal formulation strategy for brick dust substances. However, the stability of these systems to aggregation represents a big issue. To overcome this, ...
Analyzing the impact of the oil phase selection and curcumin presence on the nanoemulsion stabilizing layer using electron paramagnetic resonance spectroscopy
(8. Kongres farmaceuta Srbije; 12.-15. oktobar, Beograd, Srbija, 2022)
ANALYZING THE IMPACT OF THE OIL PHASE SELECTION AND CURCUMIN
PRESENCE ON THE NANOEMULSION STABILIZING LAYER USING ELECTRON
PARAMAGNETIC RESONANCE SPECTROSCOPY
Jelena Đoković1*, Sotiria Demisli2, Vassiliki Papadimitrio ...
Estimation of endotoxin level in nanocrystal dispersion of DK-I-56-1 intended for parenteral administration
(NANOGVA Symposium, October 5th - 6th, 2023, Geneva, Switzerland, 2023)
Estimation of endotoxin level in nanocrystal dispersion of DK-I-56-1 intended for parenteral administration
Jelena Mitrović1, Tanja Ilić1, Ivan Jančić2, Biljana Bufan2, Miroslav Savić3, Snežana Savić1
1 Department of ...
Preformulation and development of preliminary nanoemulsion carrier for patent protected compound GL-II-73
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Nanopharmaceuticals offer a good option to avoid
some of the difficulties that novel drug candidates
confront. They can be tailored to adjust their water
solubility, half-life, biodistribution, and govern the release
of ...
The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions
(MDPI, 2022)
A nanotechnology-based approach to drug delivery presents one of the biggest trends in biomedical science that can provide increased active concentration, bioavailability, and safety compared to conventional drug-delivery ...
Investigation of albumin adsorption on DK-I-56-1 nanocrystals by dynamic light scattering
(8. Kongres farmaceuta Srbije; 12.-15. oktobar, Beograd, Srbija, 2022)
After parenteral administration, nanoparticles interact with different proteins,
forming a shell called corona, which further influence nanoparticles’ biodistribution. Protein
adsorption is affected by particle size and ...