UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms
Samo za registrovane korisnike
2003
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Maprotiline, desipramine and moclobemide are widely used in the treatment of depression. The content of these antidepressants in bulk drug and pharmaceutical formulations were determined by TLC and in situ densitometry using a Camag scanner In order to achieve the best condition, mathematical statistical model factorial design was chosen. The partition coefficients, calculated by applying commercial drug design software, were correlated with chromatographic behaviour of these substances. After separation on Silica gel GF(254) using propano-lethanol-ammonium solution (25%) (8:2:0.3 v/v/v) as the mobile phase, the chromatographic zones corresponding to the spots were scanned at 254 nm. Analysing Maprotilin(R) tablets, Pertofran(R) dragees and Auromid(R) film tablets examined the applicability of the method for samples and dosage forms.
Izvor:
Chromatographia, 2003, 57, 9-10, 687-689Izdavač:
- Vieweg, Wiesbaden
DOI: 10.1007/BF02491750
ISSN: 0009-5893
WoS: 000183320400020
Scopus: 2-s2.0-0037617987
Institucija/grupa
PharmacyTY - JOUR AU - Vujić, Zorica AU - Radulović, D AU - Lucić, B AU - Erić, Slavica AU - Kuntić, Vesna PY - 2003 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/414 AB - Maprotiline, desipramine and moclobemide are widely used in the treatment of depression. The content of these antidepressants in bulk drug and pharmaceutical formulations were determined by TLC and in situ densitometry using a Camag scanner In order to achieve the best condition, mathematical statistical model factorial design was chosen. The partition coefficients, calculated by applying commercial drug design software, were correlated with chromatographic behaviour of these substances. After separation on Silica gel GF(254) using propano-lethanol-ammonium solution (25%) (8:2:0.3 v/v/v) as the mobile phase, the chromatographic zones corresponding to the spots were scanned at 254 nm. Analysing Maprotilin(R) tablets, Pertofran(R) dragees and Auromid(R) film tablets examined the applicability of the method for samples and dosage forms. PB - Vieweg, Wiesbaden T2 - Chromatographia T1 - UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms VL - 57 IS - 9-10 SP - 687 EP - 689 DO - 10.1007/BF02491750 ER -
@article{ author = "Vujić, Zorica and Radulović, D and Lucić, B and Erić, Slavica and Kuntić, Vesna", year = "2003", abstract = "Maprotiline, desipramine and moclobemide are widely used in the treatment of depression. The content of these antidepressants in bulk drug and pharmaceutical formulations were determined by TLC and in situ densitometry using a Camag scanner In order to achieve the best condition, mathematical statistical model factorial design was chosen. The partition coefficients, calculated by applying commercial drug design software, were correlated with chromatographic behaviour of these substances. After separation on Silica gel GF(254) using propano-lethanol-ammonium solution (25%) (8:2:0.3 v/v/v) as the mobile phase, the chromatographic zones corresponding to the spots were scanned at 254 nm. Analysing Maprotilin(R) tablets, Pertofran(R) dragees and Auromid(R) film tablets examined the applicability of the method for samples and dosage forms.", publisher = "Vieweg, Wiesbaden", journal = "Chromatographia", title = "UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms", volume = "57", number = "9-10", pages = "687-689", doi = "10.1007/BF02491750" }
Vujić, Z., Radulović, D., Lucić, B., Erić, S.,& Kuntić, V.. (2003). UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms. in Chromatographia Vieweg, Wiesbaden., 57(9-10), 687-689. https://doi.org/10.1007/BF02491750
Vujić Z, Radulović D, Lucić B, Erić S, Kuntić V. UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms. in Chromatographia. 2003;57(9-10):687-689. doi:10.1007/BF02491750 .
Vujić, Zorica, Radulović, D, Lucić, B, Erić, Slavica, Kuntić, Vesna, "UV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage forms" in Chromatographia, 57, no. 9-10 (2003):687-689, https://doi.org/10.1007/BF02491750 . .