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How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips
Stavovi i saveti vezani za izbor farmaceutskih oblika lekova za lečenje respiratornih infekcija kod dece
dc.creator | Cvijić, Sandra | |
dc.creator | Mirković, Dušica | |
dc.creator | Krajišnik, Danina | |
dc.date.accessioned | 2022-09-01T11:54:54Z | |
dc.date.available | 2022-09-01T11:54:54Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 0004-1963 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/4260 | |
dc.description.abstract | The treatment of respiratory infections in children requires special attention, since the paediatric population has rather specific characteristics and consists of heterogenous subgroups. In this context, the choice of a suitable drug dosage form is of particular importance, depending on the active substance properties, along with the age and general condition of a paediatric patient. Тhe most commonly used pharmaceutical products for respiratory infections in children include oral, parenteral and inhalation dosage forms, although a large number of drugs are not available in a suitable dosage form and/or strength for paediatric age, leading to the frequent use of unauthorized drugs (i.e., unlicensed use). Other important issues that should be considered when choosing the appropriate paediatric dosage form and/or compounding procedure are related to the careful considerations of the pharmaceutical product composition (safety of excipients) and the choice of administration/dosing device in relation to a child’s age. This paper provides an overview of paediatric dosage forms used in the treatment of respiratory infections in children, their benefits and limitations. The review includes examples of various pharmaceutical products, along with the considerations regarding administration/dosing devices. Specific characteristics of paediatric populations affecting the decision on the choice of age-appropriate paediatric formulation are also addressed. | sr |
dc.description.abstract | Terapija respiratornih infekcija kod dece zahteva posebnu pažnju, jer ovu populaciju čini specifična i izuzetno heterogena grupa pacijenata. Veoma je važno odabrati odgovarajući farmaceutski oblik leka, u skladu sa karakteristikama aktivne supstance, kao i stanjem i uzrastom deteta. U praksi se, u terapiji respiratornih infekcija kod dece, najviše koriste preparati za oralnu primenu, za parenteralnu primenu i za inhalaciju. Međutim, veliki broj lekova nije dostupan u odgovarajućem farmaceutskom obliku i/ili jačini za pedijatrijski uzrast, usled čega je česta neodobrena upotreba lekova. Prilikom izbora/izrade preparata za decu potrebno je pažljivo razmotriti i sastav preparata (bezbednost pomoćnih supstanci), kao i izbor aplikatora, u skladu sa uzrastom deteta. U ovom radu je dat prikaz farmaceutskih oblika lekova koji se koriste u terapiji respiratornih infekcija kod dece, njihovih prednosti i izvesnih nedostataka. Navedeni su različiti primeri farmaceutskih preparata, uz poseban osvrt na izbor aplikatora za primenu/doziranje lekova. Takođe, diskutovane su specifičnosti pedijatrijske populacije koje utiču na izbor odgovarajuće formulacije leka prilagođene uzrastu deteta. | sr |
dc.language.iso | sr | sr |
dc.language.iso | en | sr |
dc.publisher | Beograd : Savez farmaceutskih udruženja Srbije | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200161/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by-sa/4.0/ | |
dc.source | Arhiv za farmaciju | sr |
dc.subject | Paediatric dosage forms | sr |
dc.subject | age-appropriate formulation | sr |
dc.subject | extemporaneous compounding | sr |
dc.subject | administration/dosing devices | sr |
dc.subject | respiratory infections | sr |
dc.subject | farmaceutski oblici lekova za decu | sr |
dc.subject | lekovi prilagođeni pedijatrijskom uzrastu | sr |
dc.subject | izrada magistralnih lekova | sr |
dc.subject | aplikatori za primenu/doziranje lekova | sr |
dc.subject | respiratorne infekcije | sr |
dc.title | How to choose an appropriate drug dosage form for the treatment of respiratory infections in children: Facts and tips | sr |
dc.title | Stavovi i saveti vezani za izbor farmaceutskih oblika lekova za lečenje respiratornih infekcija kod dece | sr |
dc.type | article | sr |
dc.rights.license | BY-SA | sr |
dc.citation.volume | 72 | |
dc.citation.issue | 3 | |
dc.citation.spage | 353 | |
dc.citation.epage | 372 | |
dc.citation.rank | M52 | |
dc.identifier.doi | 10.5937/arhfarm72-37643 | |
dc.identifier.scopus | 2-s2.0-85140455048 | |
dc.identifier.fulltext | http://farfar.pharmacy.bg.ac.rs/bitstream/id/10286/How_to_choose_pub_2022.pdf | |
dc.type.version | publishedVersion | sr |