The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers
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The formation and properties of polyelectrolyte
complexes (PECs) based on chitosan (CH) and xanthan
gum (XG) depend on various preparation parameters (pH
value, ionic strength, mixing order of polyelectrolytes,
etc.). The extent of polyelectrolytes interactions can
significantly influence the achievement of the desired drug
release kinetics from the PECs (Ćirić et al., 2022). The
dissolution of CH is one of the essential requirements
influencing the formation and properties of PECs. Previous
research has shown that CH dissolves in dilute solutions of
acids at a pH < 6.3 (Furuike et al., 2017). Therefore, this
research aimed to determine the influence of pH and the
type of pH-adjusting agent on the formation and extent of
interactions in PECs based on CH and XG. ...
Source:
Macedonian Pharmaceutical Bulletin, 2023, 69, Suppl 1, 51-52Publisher:
- Macedonian Pharmaceutical Association
- Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200161 (University of Belgrade, Faculty of Pharmacy) (RS-MESTD-inst-2020-200161)
Note:
- 14th Central European Symposium on Pharmaceutical Technology, 28th - 30th September, Ohrid, N. Macedonia, 2023
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Institution/Community
PharmacyTY - CONF AU - Ćirić, Ana AU - Đekić, Ljiljana PY - 2023 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5051 AB - The formation and properties of polyelectrolyte complexes (PECs) based on chitosan (CH) and xanthan gum (XG) depend on various preparation parameters (pH value, ionic strength, mixing order of polyelectrolytes, etc.). The extent of polyelectrolytes interactions can significantly influence the achievement of the desired drug release kinetics from the PECs (Ćirić et al., 2022). The dissolution of CH is one of the essential requirements influencing the formation and properties of PECs. Previous research has shown that CH dissolves in dilute solutions of acids at a pH < 6.3 (Furuike et al., 2017). Therefore, this research aimed to determine the influence of pH and the type of pH-adjusting agent on the formation and extent of interactions in PECs based on CH and XG. ... PB - Macedonian Pharmaceutical Association PB - Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy C3 - Macedonian Pharmaceutical Bulletin T1 - The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers VL - 69 IS - Suppl 1 SP - 51 EP - 52 DO - 10.33320/maced.pharm.bull.2023.69.03.025 ER -
@conference{ author = "Ćirić, Ana and Đekić, Ljiljana", year = "2023", abstract = "The formation and properties of polyelectrolyte complexes (PECs) based on chitosan (CH) and xanthan gum (XG) depend on various preparation parameters (pH value, ionic strength, mixing order of polyelectrolytes, etc.). The extent of polyelectrolytes interactions can significantly influence the achievement of the desired drug release kinetics from the PECs (Ćirić et al., 2022). The dissolution of CH is one of the essential requirements influencing the formation and properties of PECs. Previous research has shown that CH dissolves in dilute solutions of acids at a pH < 6.3 (Furuike et al., 2017). Therefore, this research aimed to determine the influence of pH and the type of pH-adjusting agent on the formation and extent of interactions in PECs based on CH and XG. ...", publisher = "Macedonian Pharmaceutical Association, Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy", journal = "Macedonian Pharmaceutical Bulletin", title = "The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers", volume = "69", number = "Suppl 1", pages = "51-52", doi = "10.33320/maced.pharm.bull.2023.69.03.025" }
Ćirić, A.,& Đekić, L.. (2023). The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers. in Macedonian Pharmaceutical Bulletin Macedonian Pharmaceutical Association., 69(Suppl 1), 51-52. https://doi.org/10.33320/maced.pharm.bull.2023.69.03.025
Ćirić A, Đekić L. The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers. in Macedonian Pharmaceutical Bulletin. 2023;69(Suppl 1):51-52. doi:10.33320/maced.pharm.bull.2023.69.03.025 .
Ćirić, Ana, Đekić, Ljiljana, "The influence of preparation conditions on the formation and extent of interactions in chitosan/xanthan gum polyelectrolyte complexes as potential drug delivery carriers" in Macedonian Pharmaceutical Bulletin, 69, no. Suppl 1 (2023):51-52, https://doi.org/10.33320/maced.pharm.bull.2023.69.03.025 . .