The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91
Uticaj tipa masne faze na fizičko-hemijske i reološke osobine kremova stabilisanih polimernim emulgatorom Salcare SC 91
Apstrakt
In this work results of model creams investigation containing polymeric emulsifier in the form of „Liquid Dispersion Polymers”, Salcare® SC 91 (Sodium acrylates/paraffinum liquidum/PPG-1 Trideceth-6; 3 % (m/m)) and 30 % (m/m) of different polarity oil phases (paraffin, light liqiud; medium-chain triglycerides and almond oil) are presented. For physico-chemical characterization and physical stability assessment of prepared creams investigations of appearance, physical stability, pH value and electrical conductivity alongside with rheological measurements (rotational and oscillatory) in the period of three months were performed. All the tested samples had good macroscopic behavior and physical stability and their pH values were acceptable for topical application. Rheological measurements revealed that oil phase type had great influence on applicative characteristics and stability of emulsion systems. Model cream samples prepared with more polar oil phases had better stability than cream ...containing less polar phase.
U radu su prikazani rezultati ispitivanja model kremova izrađenih sa polimernim emulgatorom u formi tečne disperzije, Salcare® SC 91 (Natrijum Akrilat Kopolimer/Tečni parafin/PPG-1 Tridecet-6; 3 % (m/m)) i 30 % (m/m) masne faze različite polarnosti (tečni laki parafin, trigliceridi srednje dužine lanca i bademovo ulje). U cilju fizičko-hemijske karakterizacije i procene stabilnosti izrađenih kremova sprovedena su ispitivanja izgleda, fizičke stabilnosti, pH vrednosti i električne provodljivosti kao i reološka analiza (kontinualna i oscilatorna) u periodu od 3 meseca. Svi ispitivani uzorci pokazali su zadovoljavajući izgled i fizičku stabilnost a vrednosti pH bile su u opsegu prihvatljivom za preparate za primenu na kožu. Reološka merenja su pokazala da tip upotrebljene masne faze može imati znatan uticaj na aplikativne karakteristike i stabilnosti datih emulzionih sistema. Uzorci model kremova izrađenih sa masnim fazama veće polarnosti pokazali su se stabilnijim u odnosu na krem sa naj...manje polarnom masnom fazom.
Ključne reči:
polymeric emulsifier / liquid dispersion polymers / o/w creams / oil phase polarity / rheological measurements / physical stability / polimerni emulgator / tečna disperzija polimera / u/v kremovi / polarnost masne faze / reološka merenja / fizička stabilnostIzvor:
Arhiv za farmaciju, 2004, 54, 5, 613-628Izdavač:
- Savez farmaceutskih udruženja Srbije, Beograd
Institucija/grupa
PharmacyTY - JOUR AU - Krajišnik, Danina AU - Milić-Aškrabić, Jela AU - Vuleta, Gordana AU - Stupar, Mirjana PY - 2004 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/506 AB - In this work results of model creams investigation containing polymeric emulsifier in the form of „Liquid Dispersion Polymers”, Salcare® SC 91 (Sodium acrylates/paraffinum liquidum/PPG-1 Trideceth-6; 3 % (m/m)) and 30 % (m/m) of different polarity oil phases (paraffin, light liqiud; medium-chain triglycerides and almond oil) are presented. For physico-chemical characterization and physical stability assessment of prepared creams investigations of appearance, physical stability, pH value and electrical conductivity alongside with rheological measurements (rotational and oscillatory) in the period of three months were performed. All the tested samples had good macroscopic behavior and physical stability and their pH values were acceptable for topical application. Rheological measurements revealed that oil phase type had great influence on applicative characteristics and stability of emulsion systems. Model cream samples prepared with more polar oil phases had better stability than cream containing less polar phase. AB - U radu su prikazani rezultati ispitivanja model kremova izrađenih sa polimernim emulgatorom u formi tečne disperzije, Salcare® SC 91 (Natrijum Akrilat Kopolimer/Tečni parafin/PPG-1 Tridecet-6; 3 % (m/m)) i 30 % (m/m) masne faze različite polarnosti (tečni laki parafin, trigliceridi srednje dužine lanca i bademovo ulje). U cilju fizičko-hemijske karakterizacije i procene stabilnosti izrađenih kremova sprovedena su ispitivanja izgleda, fizičke stabilnosti, pH vrednosti i električne provodljivosti kao i reološka analiza (kontinualna i oscilatorna) u periodu od 3 meseca. Svi ispitivani uzorci pokazali su zadovoljavajući izgled i fizičku stabilnost a vrednosti pH bile su u opsegu prihvatljivom za preparate za primenu na kožu. Reološka merenja su pokazala da tip upotrebljene masne faze može imati znatan uticaj na aplikativne karakteristike i stabilnosti datih emulzionih sistema. Uzorci model kremova izrađenih sa masnim fazama veće polarnosti pokazali su se stabilnijim u odnosu na krem sa najmanje polarnom masnom fazom. PB - Savez farmaceutskih udruženja Srbije, Beograd T2 - Arhiv za farmaciju T1 - The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91 T1 - Uticaj tipa masne faze na fizičko-hemijske i reološke osobine kremova stabilisanih polimernim emulgatorom Salcare SC 91 VL - 54 IS - 5 SP - 613 EP - 628 UR - https://hdl.handle.net/21.15107/rcub_farfar_506 ER -
@article{ author = "Krajišnik, Danina and Milić-Aškrabić, Jela and Vuleta, Gordana and Stupar, Mirjana", year = "2004", abstract = "In this work results of model creams investigation containing polymeric emulsifier in the form of „Liquid Dispersion Polymers”, Salcare® SC 91 (Sodium acrylates/paraffinum liquidum/PPG-1 Trideceth-6; 3 % (m/m)) and 30 % (m/m) of different polarity oil phases (paraffin, light liqiud; medium-chain triglycerides and almond oil) are presented. For physico-chemical characterization and physical stability assessment of prepared creams investigations of appearance, physical stability, pH value and electrical conductivity alongside with rheological measurements (rotational and oscillatory) in the period of three months were performed. All the tested samples had good macroscopic behavior and physical stability and their pH values were acceptable for topical application. Rheological measurements revealed that oil phase type had great influence on applicative characteristics and stability of emulsion systems. Model cream samples prepared with more polar oil phases had better stability than cream containing less polar phase., U radu su prikazani rezultati ispitivanja model kremova izrađenih sa polimernim emulgatorom u formi tečne disperzije, Salcare® SC 91 (Natrijum Akrilat Kopolimer/Tečni parafin/PPG-1 Tridecet-6; 3 % (m/m)) i 30 % (m/m) masne faze različite polarnosti (tečni laki parafin, trigliceridi srednje dužine lanca i bademovo ulje). U cilju fizičko-hemijske karakterizacije i procene stabilnosti izrađenih kremova sprovedena su ispitivanja izgleda, fizičke stabilnosti, pH vrednosti i električne provodljivosti kao i reološka analiza (kontinualna i oscilatorna) u periodu od 3 meseca. Svi ispitivani uzorci pokazali su zadovoljavajući izgled i fizičku stabilnost a vrednosti pH bile su u opsegu prihvatljivom za preparate za primenu na kožu. Reološka merenja su pokazala da tip upotrebljene masne faze može imati znatan uticaj na aplikativne karakteristike i stabilnosti datih emulzionih sistema. Uzorci model kremova izrađenih sa masnim fazama veće polarnosti pokazali su se stabilnijim u odnosu na krem sa najmanje polarnom masnom fazom.", publisher = "Savez farmaceutskih udruženja Srbije, Beograd", journal = "Arhiv za farmaciju", title = "The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91, Uticaj tipa masne faze na fizičko-hemijske i reološke osobine kremova stabilisanih polimernim emulgatorom Salcare SC 91", volume = "54", number = "5", pages = "613-628", url = "https://hdl.handle.net/21.15107/rcub_farfar_506" }
Krajišnik, D., Milić-Aškrabić, J., Vuleta, G.,& Stupar, M.. (2004). The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91. in Arhiv za farmaciju Savez farmaceutskih udruženja Srbije, Beograd., 54(5), 613-628. https://hdl.handle.net/21.15107/rcub_farfar_506
Krajišnik D, Milić-Aškrabić J, Vuleta G, Stupar M. The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91. in Arhiv za farmaciju. 2004;54(5):613-628. https://hdl.handle.net/21.15107/rcub_farfar_506 .
Krajišnik, Danina, Milić-Aškrabić, Jela, Vuleta, Gordana, Stupar, Mirjana, "The influence of oil phase type on physicochemical and rheological properties of creams stabilized with polymeric emulsifier Salcare® SC 91" in Arhiv za farmaciju, 54, no. 5 (2004):613-628, https://hdl.handle.net/21.15107/rcub_farfar_506 .