Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro
Abstract
Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols exhibit antitumor, anti-inflamatory, hypoglycemic, immunomodulatory effects, as well as antioxidative properties. Oxidative stress and increased ROS levels lead to tissue damage, with DNA molecule being particularly susceptible to oxidative damage. ...
Keywords:
Inonotus obliquus / chaga / DNA damage / comet assaySource:
13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow, 2019, 54-54Publisher:
- International Comet Assay Working Group (ICAWG)
Funding / projects:
- Cell Cycle Aberrations and the Impact of Oxidative Stress in Neurodegenerative Processes and Malignant Transformation of the Cell (RS-MESTD-Basic Research (BR or ON)-173034)
Note:
- ICAW 2019
Collections
Institution/Community
PharmacyTY - CONF AU - Bruić, Marija AU - Živković, Lada AU - Bajić, Vladan AU - Topalović, Dijana AU - Spremo-Potparević, Biljana PY - 2019 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5151 AB - Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols exhibit antitumor, anti-inflamatory, hypoglycemic, immunomodulatory effects, as well as antioxidative properties. Oxidative stress and increased ROS levels lead to tissue damage, with DNA molecule being particularly susceptible to oxidative damage. ... PB - International Comet Assay Working Group (ICAWG) C3 - 13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow T1 - Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro SP - 54 EP - 54 UR - https://hdl.handle.net/21.15107/rcub_farfar_5151 ER -
@conference{ author = "Bruić, Marija and Živković, Lada and Bajić, Vladan and Topalović, Dijana and Spremo-Potparević, Biljana", year = "2019", abstract = "Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols exhibit antitumor, anti-inflamatory, hypoglycemic, immunomodulatory effects, as well as antioxidative properties. Oxidative stress and increased ROS levels lead to tissue damage, with DNA molecule being particularly susceptible to oxidative damage. ...", publisher = "International Comet Assay Working Group (ICAWG)", journal = "13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow", title = "Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro", pages = "54-54", url = "https://hdl.handle.net/21.15107/rcub_farfar_5151" }
Bruić, M., Živković, L., Bajić, V., Topalović, D.,& Spremo-Potparević, B.. (2019). Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro. in 13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow International Comet Assay Working Group (ICAWG)., 54-54. https://hdl.handle.net/21.15107/rcub_farfar_5151
Bruić M, Živković L, Bajić V, Topalović D, Spremo-Potparević B. Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro. in 13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow. 2019;:54-54. https://hdl.handle.net/21.15107/rcub_farfar_5151 .
Bruić, Marija, Živković, Lada, Bajić, Vladan, Topalović, Dijana, Spremo-Potparević, Biljana, "Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro" in 13th International Comet Assay Workshop, 24-27 June, 2019, Pushchino, Moscow (2019):54-54, https://hdl.handle.net/21.15107/rcub_farfar_5151 .