Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams
Само за регистроване кориснике
2004
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals.
Кључне речи:
econazole nitrate / bifonazole / parabens / HPTLC / medicinal creamИзвор:
Journal of Planar Chromatography - Modern TLC, 2004, 17, 3, 177-180Издавач:
- Springer Nature
Финансирање / пројекти:
- Ministry for Science, Technology and Development of Serbia, Grant #1458.
DOI: 10.1556/JPC.17.2004.3.4
ISSN: 0933-4173
WoS: 000222956100004
Scopus: 2-s2.0-4043052270
Институција/група
PharmacyTY - JOUR AU - Čakar, Mira AU - Popović, Gordana AU - Vladimirov, Sote PY - 2004 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/524 AB - A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals. PB - Springer Nature T2 - Journal of Planar Chromatography - Modern TLC T1 - Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams VL - 17 IS - 3 SP - 177 EP - 180 DO - 10.1556/JPC.17.2004.3.4 ER -
@article{ author = "Čakar, Mira and Popović, Gordana and Vladimirov, Sote", year = "2004", abstract = "A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals.", publisher = "Springer Nature", journal = "Journal of Planar Chromatography - Modern TLC", title = "Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams", volume = "17", number = "3", pages = "177-180", doi = "10.1556/JPC.17.2004.3.4" }
Čakar, M., Popović, G.,& Vladimirov, S.. (2004). Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams. in Journal of Planar Chromatography - Modern TLC Springer Nature., 17(3), 177-180. https://doi.org/10.1556/JPC.17.2004.3.4
Čakar M, Popović G, Vladimirov S. Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams. in Journal of Planar Chromatography - Modern TLC. 2004;17(3):177-180. doi:10.1556/JPC.17.2004.3.4 .
Čakar, Mira, Popović, Gordana, Vladimirov, Sote, "Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams" in Journal of Planar Chromatography - Modern TLC, 17, no. 3 (2004):177-180, https://doi.org/10.1556/JPC.17.2004.3.4 . .