TY  - JOUR
AU  - Dimitrijević, Olivera
AU  - Đorić-Stojcevski, Blagica
AU  - Ignjatović, Svetlana
AU  - Majkić-Singh, Nada
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/713
AB  - Systemic markers of inflammation are considered reliable predictors of future coronary events in patients with acute myocardial infarction (AMI). The aim of this study was to evaluate the prognostic relevance of serial C-reactive protein (CRP) measurements in patients with ST-elevation AMI (STEMI) on one-year outcome. In 31 patients with STEMI, serial measurements of CRP were obtained, and for each patient, the following values were determined: (i) values at admission, up to 12 hours after symptom onset, (ii) maximal values obtained 24-72 hours after symptom onset (early acute values), and (iii) late acute values (96-120 hours after symptom onset). The combined endpoint was any new cardiovascular event, including death. Early and late acute CRP levels were the only parameters found to be significantly higher in patients with an adverse outcome than in patients with a good outcome. A significantly higher rate of endpoint events was found in patients with elevated early (Hazard ratio [HR] 5.54, 95%CI 2.05-25.40; P = 0.007) and late acute CRP (HR 9.01, 95% CI 1.66-19.56; P = 0.005). Multiple logistic regression analysis identified only early acute CRP as an independent predictor of an unfavorable outcome (Odds ratio 8.00, 95%CI 1.15-55.60; P 0.04), after adjustment for established risk factors. CRP level measured 24-72 hours after symptom onset is an independent predictor of one-year outcome in patients with STEML Values obtained later in the setting of STEMI do not add further prognostic information. CRP at admission is not related to long-term prognosis'.
PB  - Int Heart Journal Assoc, Tokyo
T2  - International Heart Journal
T1  - Serial measurements of C-reactive protein after acute myocardial infarction in predicting one-year outcome
VL  - 47
IS  - 6
SP  - 833
EP  - 842
DO  - 10.1536/ihj.47.833
ER  - 

@article{
author = "Dimitrijević, Olivera and Đorić-Stojcevski, Blagica and Ignjatović, Svetlana and Majkić-Singh, Nada",
year = "2006",
abstract = "Systemic markers of inflammation are considered reliable predictors of future coronary events in patients with acute myocardial infarction (AMI). The aim of this study was to evaluate the prognostic relevance of serial C-reactive protein (CRP) measurements in patients with ST-elevation AMI (STEMI) on one-year outcome. In 31 patients with STEMI, serial measurements of CRP were obtained, and for each patient, the following values were determined: (i) values at admission, up to 12 hours after symptom onset, (ii) maximal values obtained 24-72 hours after symptom onset (early acute values), and (iii) late acute values (96-120 hours after symptom onset). The combined endpoint was any new cardiovascular event, including death. Early and late acute CRP levels were the only parameters found to be significantly higher in patients with an adverse outcome than in patients with a good outcome. A significantly higher rate of endpoint events was found in patients with elevated early (Hazard ratio [HR] 5.54, 95%CI 2.05-25.40; P = 0.007) and late acute CRP (HR 9.01, 95% CI 1.66-19.56; P = 0.005). Multiple logistic regression analysis identified only early acute CRP as an independent predictor of an unfavorable outcome (Odds ratio 8.00, 95%CI 1.15-55.60; P 0.04), after adjustment for established risk factors. CRP level measured 24-72 hours after symptom onset is an independent predictor of one-year outcome in patients with STEML Values obtained later in the setting of STEMI do not add further prognostic information. CRP at admission is not related to long-term prognosis'.",
publisher = "Int Heart Journal Assoc, Tokyo",
journal = "International Heart Journal",
title = "Serial measurements of C-reactive protein after acute myocardial infarction in predicting one-year outcome",
volume = "47",
number = "6",
pages = "833-842",
doi = "10.1536/ihj.47.833"
}

Dimitrijević, O., Đorić-Stojcevski, B., Ignjatović, S.,& Majkić-Singh, N.. (2006). Serial measurements of C-reactive protein after acute myocardial infarction in predicting one-year outcome. in International Heart Journal
Int Heart Journal Assoc, Tokyo., 47(6), 833-842.
https://doi.org/10.1536/ihj.47.833

Dimitrijević O, Đorić-Stojcevski B, Ignjatović S, Majkić-Singh N. Serial measurements of C-reactive protein after acute myocardial infarction in predicting one-year outcome. in International Heart Journal. 2006;47(6):833-842.
doi:10.1536/ihj.47.833 .

Dimitrijević, Olivera, Đorić-Stojcevski, Blagica, Ignjatović, Svetlana, Majkić-Singh, Nada, "Serial measurements of C-reactive protein after acute myocardial infarction in predicting one-year outcome" in International Heart Journal, 47, no. 6 (2006):833-842,
https://doi.org/10.1536/ihj.47.833 . .