TY  - JOUR
AU  - Milinković, Neda
AU  - Majkić-Singh, Nada
AU  - Mirković, Duško
AU  - Beletić, Anđelo
AU  - Pejanović, Svetlana D.
AU  - Vujanić, Svetlana T.
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1189
AB  - Deficient serum 25-hydroxyvitamin D [25(OH)D] may contribute to the impaired bone turnover of end stage renal disease patients. In 112 hemodialysed patients we analysed the relation between 25(OH)D and bone alkaline phosphatase (BALP), beta-CrossLaps (beta-CTx) and iPTH. We analysed parameters according to the manufacturers' instructions. We found potentially significant vitamin D deficiency: 71% of patients had 25(OH)D levels below 50 nmol/L. In patients with iPTH below 150 pg/mL (n = 57), we observed significantly low 25(OH) (p lt 0.01). In addition, patients with iPTH above 300 pg/mL had higher BALP levels (p lt 0.05). There were negative correlations between serum 25(OH)D and both BALP and iPTH (r = -0.225, p lt 0.05 and r = -0.331, p lt 0.05). Beta-CTx levels were significantly higher in patients who did not receive vitamin D supplementation (p lt 0.01). In addition, reduced BALP and iPTH levels indicate decreased bone turnover. Recorded data could signify that vitamin D deficiency may contribute to the impaired bone metabolism of hemodialysis patients. (Clin. Lab. 2009;55:333-339)
PB  - Clin Lab Publ, Heidelberg
T2  - Clinical Laboratory
T1  - Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients
VL  - 55
IS  - 9-10
SP  - 333
EP  - 339
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1189
ER  - 

@article{
author = "Milinković, Neda and Majkić-Singh, Nada and Mirković, Duško and Beletić, Anđelo and Pejanović, Svetlana D. and Vujanić, Svetlana T.",
year = "2009",
abstract = "Deficient serum 25-hydroxyvitamin D [25(OH)D] may contribute to the impaired bone turnover of end stage renal disease patients. In 112 hemodialysed patients we analysed the relation between 25(OH)D and bone alkaline phosphatase (BALP), beta-CrossLaps (beta-CTx) and iPTH. We analysed parameters according to the manufacturers' instructions. We found potentially significant vitamin D deficiency: 71% of patients had 25(OH)D levels below 50 nmol/L. In patients with iPTH below 150 pg/mL (n = 57), we observed significantly low 25(OH) (p lt 0.01). In addition, patients with iPTH above 300 pg/mL had higher BALP levels (p lt 0.05). There were negative correlations between serum 25(OH)D and both BALP and iPTH (r = -0.225, p lt 0.05 and r = -0.331, p lt 0.05). Beta-CTx levels were significantly higher in patients who did not receive vitamin D supplementation (p lt 0.01). In addition, reduced BALP and iPTH levels indicate decreased bone turnover. Recorded data could signify that vitamin D deficiency may contribute to the impaired bone metabolism of hemodialysis patients. (Clin. Lab. 2009;55:333-339)",
publisher = "Clin Lab Publ, Heidelberg",
journal = "Clinical Laboratory",
title = "Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients",
volume = "55",
number = "9-10",
pages = "333-339",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1189"
}

Milinković, N., Majkić-Singh, N., Mirković, D., Beletić, A., Pejanović, S. D.,& Vujanić, S. T.. (2009). Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients. in Clinical Laboratory
Clin Lab Publ, Heidelberg., 55(9-10), 333-339.
https://hdl.handle.net/21.15107/rcub_farfar_1189

Milinković N, Majkić-Singh N, Mirković D, Beletić A, Pejanović SD, Vujanić ST. Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients. in Clinical Laboratory. 2009;55(9-10):333-339.
https://hdl.handle.net/21.15107/rcub_farfar_1189 .

Milinković, Neda, Majkić-Singh, Nada, Mirković, Duško, Beletić, Anđelo, Pejanović, Svetlana D., Vujanić, Svetlana T., "Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients" in Clinical Laboratory, 55, no. 9-10 (2009):333-339,
https://hdl.handle.net/21.15107/rcub_farfar_1189 .