TY  - JOUR
AU  - Ceulemans, Michael
AU  - Lupattelli, Angela
AU  - Nordeng, Hedvig
AU  - Odalović, Marina
AU  - Twigg, Michael J.
AU  - Foulon, Veerle
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3348
AB  - Background: During pregnancy, women might weigh the benefits of treatment against potential risks to the unborn child. However, non-adherence to necessary treatment can adversely affect both mother and child. To optimize pregnant women's beliefs and medication adherence, community pharmacists are ideally positioned to play an important role in primary care. Objective: This narrative review aimed to summarize the evidence on 1) pregnant women's beliefs, 2) medication adherence in pregnancy and 3) community pharmacists' counselling during pregnancy. Methods: Three search strategies were used in Medline and Embase to find original studies evaluating women's beliefs, medication adherence and community pharmacists' counselling during pregnancy. All original descriptive and analytic epidemiological studies performed in Europe, North America and Australia, written in English and published from 2000 onwards were included. Results: We included 14 studies reporting on women's beliefs, 11 studies on medication adherence and 9 on community pharmacists' counselling during pregnancy. Women are more reluctant to use medicines during pregnancy and tend to overestimate the teratogenic risk of medicines. The risk perception varies with the type of medicine, level of health literacy, education level and occupation. Furthermore, low medication adherence during pregnancy is common. Finally, limited evidence showed that the current community pharmacists' counselling is insufficient. Barriers hindering pharmacists are insufficient knowledge and limited access to reliable information. Conclusion: Concerns about medication use and non-adherence are widespread among pregnant women. Community pharmacists' counselling during pregnancy is insufficient. Further education, training and research are required to support community pharmacists in fulfilling all the opportunities they have when counselling pregnant women.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Design
T1  - Women's Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists
VL  - 25
IS  - 5
SP  - 469
EP  - 482
DO  - 10.2174/1381612825666190321110420
ER  - 

@article{
author = "Ceulemans, Michael and Lupattelli, Angela and Nordeng, Hedvig and Odalović, Marina and Twigg, Michael J. and Foulon, Veerle",
year = "2019",
abstract = "Background: During pregnancy, women might weigh the benefits of treatment against potential risks to the unborn child. However, non-adherence to necessary treatment can adversely affect both mother and child. To optimize pregnant women's beliefs and medication adherence, community pharmacists are ideally positioned to play an important role in primary care. Objective: This narrative review aimed to summarize the evidence on 1) pregnant women's beliefs, 2) medication adherence in pregnancy and 3) community pharmacists' counselling during pregnancy. Methods: Three search strategies were used in Medline and Embase to find original studies evaluating women's beliefs, medication adherence and community pharmacists' counselling during pregnancy. All original descriptive and analytic epidemiological studies performed in Europe, North America and Australia, written in English and published from 2000 onwards were included. Results: We included 14 studies reporting on women's beliefs, 11 studies on medication adherence and 9 on community pharmacists' counselling during pregnancy. Women are more reluctant to use medicines during pregnancy and tend to overestimate the teratogenic risk of medicines. The risk perception varies with the type of medicine, level of health literacy, education level and occupation. Furthermore, low medication adherence during pregnancy is common. Finally, limited evidence showed that the current community pharmacists' counselling is insufficient. Barriers hindering pharmacists are insufficient knowledge and limited access to reliable information. Conclusion: Concerns about medication use and non-adherence are widespread among pregnant women. Community pharmacists' counselling during pregnancy is insufficient. Further education, training and research are required to support community pharmacists in fulfilling all the opportunities they have when counselling pregnant women.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Design",
title = "Women's Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists",
volume = "25",
number = "5",
pages = "469-482",
doi = "10.2174/1381612825666190321110420"
}

Ceulemans, M., Lupattelli, A., Nordeng, H., Odalović, M., Twigg, M. J.,& Foulon, V.. (2019). Women's Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists. in Current Pharmaceutical Design
Bentham Science Publ Ltd, Sharjah., 25(5), 469-482.
https://doi.org/10.2174/1381612825666190321110420

Ceulemans M, Lupattelli A, Nordeng H, Odalović M, Twigg MJ, Foulon V. Women's Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists. in Current Pharmaceutical Design. 2019;25(5):469-482.
doi:10.2174/1381612825666190321110420 .

Ceulemans, Michael, Lupattelli, Angela, Nordeng, Hedvig, Odalović, Marina, Twigg, Michael J., Foulon, Veerle, "Women's Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists" in Current Pharmaceutical Design, 25, no. 5 (2019):469-482,
https://doi.org/10.2174/1381612825666190321110420 . .

TY  - JOUR
AU  - Lupattelli, Angela
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Rieutord, Andre
AU  - Juraski, Romana Gjergja
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Nordeng, Hedvig
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3227
AB  - Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and postnatal symptom severity. Materials and methods: This was a multinational web-based study conducted across 12 European countries (n=8069). Uniform data collection was ensured via an electronic questionnaire. Pregnant women at any gestational week and mothers of children with  lt 1 year of age could participate. We used the Edinburgh Postnatal Depression Scale (EPDS) to measure the prevalence of antenatal and postnatal depressive symptoms according to severity, which were corrected by survey weight adjustment (descriptive analysis). Within mothers with a psychiatric disorder (n=173), we estimated the association between antidepressant treatment in pregnancy and postnatal depressive symptom severity, as standardized EPDS mean scores, via the inverse probability of treatment weight (association analysis). Results: In the descriptive analysis (n=8069), the period prevalence of moderate-to-very severe depressive symptoms was higher in the western and eastern regions relative to the northern region, both in the antenatal period (6.8%-7.5% vs 4.3%) and in the postnatal period (7.6% vs 4.7%). One in two mothers with psychiatric disorders used an antidepressant in pregnancy (86 of 173). In the association analysis, women medicated at any time during pregnancy (adjusted beta=-0.34, 95% confidence interval [CI] =-0.66, -0.02) had a significant postnatal symptom severity reduction compared with the nonmedicated counterpart. This effect was larger (beta=-0.74, 95% CI =-1.24, -0.24) when the analysis was restricted to mothers within 6 months after childbirth. Conclusion: The prevalence of self-reported antenatal and postnatal depressive symptoms differs across European countries. Among women with psychiatric disorders, those who had been on treatment with antidepressants during pregnancy were less likely to report postnatal depressive symptoms, particularly within the 6-month period after childbirth, compared with the nonmedicated counterpart.
PB  - Dove Medical Press Ltd, Albany
T2  - Clinical Epidemiology
T1  - Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale
VL  - 10
SP  - 655
EP  - 669
DO  - 10.2147/CLEP.S156210
ER  - 

@article{
author = "Lupattelli, Angela and Twigg, Michael J. and Zagorodnikova, Ksenia and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Rieutord, Andre and Juraski, Romana Gjergja and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Nordeng, Hedvig",
year = "2018",
abstract = "Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and postnatal symptom severity. Materials and methods: This was a multinational web-based study conducted across 12 European countries (n=8069). Uniform data collection was ensured via an electronic questionnaire. Pregnant women at any gestational week and mothers of children with  lt 1 year of age could participate. We used the Edinburgh Postnatal Depression Scale (EPDS) to measure the prevalence of antenatal and postnatal depressive symptoms according to severity, which were corrected by survey weight adjustment (descriptive analysis). Within mothers with a psychiatric disorder (n=173), we estimated the association between antidepressant treatment in pregnancy and postnatal depressive symptom severity, as standardized EPDS mean scores, via the inverse probability of treatment weight (association analysis). Results: In the descriptive analysis (n=8069), the period prevalence of moderate-to-very severe depressive symptoms was higher in the western and eastern regions relative to the northern region, both in the antenatal period (6.8%-7.5% vs 4.3%) and in the postnatal period (7.6% vs 4.7%). One in two mothers with psychiatric disorders used an antidepressant in pregnancy (86 of 173). In the association analysis, women medicated at any time during pregnancy (adjusted beta=-0.34, 95% confidence interval [CI] =-0.66, -0.02) had a significant postnatal symptom severity reduction compared with the nonmedicated counterpart. This effect was larger (beta=-0.74, 95% CI =-1.24, -0.24) when the analysis was restricted to mothers within 6 months after childbirth. Conclusion: The prevalence of self-reported antenatal and postnatal depressive symptoms differs across European countries. Among women with psychiatric disorders, those who had been on treatment with antidepressants during pregnancy were less likely to report postnatal depressive symptoms, particularly within the 6-month period after childbirth, compared with the nonmedicated counterpart.",
publisher = "Dove Medical Press Ltd, Albany",
journal = "Clinical Epidemiology",
title = "Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale",
volume = "10",
pages = "655-669",
doi = "10.2147/CLEP.S156210"
}

Lupattelli, A., Twigg, M. J., Zagorodnikova, K., Moretti, M. E., Drozd, M., Panchaud, A., Rieutord, A., Juraski, R. G., Odalović, M., Kennedy, D., Rudolf, G., Juch, H.,& Nordeng, H.. (2018). Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale. in Clinical Epidemiology
Dove Medical Press Ltd, Albany., 10, 655-669.
https://doi.org/10.2147/CLEP.S156210

Lupattelli A, Twigg MJ, Zagorodnikova K, Moretti ME, Drozd M, Panchaud A, Rieutord A, Juraski RG, Odalović M, Kennedy D, Rudolf G, Juch H, Nordeng H. Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale. in Clinical Epidemiology. 2018;10:655-669.
doi:10.2147/CLEP.S156210 .

Lupattelli, Angela, Twigg, Michael J., Zagorodnikova, Ksenia, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Rieutord, Andre, Juraski, Romana Gjergja, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Nordeng, Hedvig, "Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale" in Clinical Epidemiology, 10 (2018):655-669,
https://doi.org/10.2147/CLEP.S156210 . .

TY  - CONF
AU  - Odalović, Marina
AU  - Milanković, Silje
AU  - Host, Lone
AU  - Nordeng, Hedvig
AU  - Heitmann, Kristine
AU  - Tasić, Ljiljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2705
PB  - Springer
C3  - International Journal of Clinical Pharmacy
T1  - Pharmacist interventions in pregnant women: comparative study between Serbia and Norway
VL  - 38
IS  - 4
SP  - 1018
EP  - 1018
DO  - 10.1007/s11096-016-0283-8
ER  - 

@conference{
author = "Odalović, Marina and Milanković, Silje and Host, Lone and Nordeng, Hedvig and Heitmann, Kristine and Tasić, Ljiljana",
year = "2016",
publisher = "Springer",
journal = "International Journal of Clinical Pharmacy",
title = "Pharmacist interventions in pregnant women: comparative study between Serbia and Norway",
volume = "38",
number = "4",
pages = "1018-1018",
doi = "10.1007/s11096-016-0283-8"
}

Odalović, M., Milanković, S., Host, L., Nordeng, H., Heitmann, K.,& Tasić, L.. (2016). Pharmacist interventions in pregnant women: comparative study between Serbia and Norway. in International Journal of Clinical Pharmacy
Springer., 38(4), 1018-1018.
https://doi.org/10.1007/s11096-016-0283-8

Odalović M, Milanković S, Host L, Nordeng H, Heitmann K, Tasić L. Pharmacist interventions in pregnant women: comparative study between Serbia and Norway. in International Journal of Clinical Pharmacy. 2016;38(4):1018-1018.
doi:10.1007/s11096-016-0283-8 .

Odalović, Marina, Milanković, Silje, Host, Lone, Nordeng, Hedvig, Heitmann, Kristine, Tasić, Ljiljana, "Pharmacist interventions in pregnant women: comparative study between Serbia and Norway" in International Journal of Clinical Pharmacy, 38, no. 4 (2016):1018-1018,
https://doi.org/10.1007/s11096-016-0283-8 . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Milanković, Silje
AU  - Holst, Lone
AU  - Nordeng, Hedvig
AU  - Heitmann, Kristine
AU  - Tasić, Ljiljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2694
AB  - Objectives: To describe, compare and evaluate whether pharmacists in two European countries, Serbia and Norway, give appropriate counselling for common ailments in pregnancy. Design: A cross sectional, web-based study. Participants and Settings: A study was conducted among Serbian and Norwegian pharmacists during two four-month study periods in 2012 respectively 2014. Participants were recruited through postal and electronic invitation facilitated by several pharmacy chains. Participation in the study was anonymous and voluntary. Measurement instrument: Pharmacists were presented with the questionnaire that included five scenarios (back pain, heavy legs, nausea, cold and constipation in pregnancy) and were asked to give their advice about use of medicines, supplements (e.g. herbal products, vitamins, minerals), non-pharmacological treatment and referral to physician in each condition. Findings: In total, 276 pharmacists, 119 in Serbia and 157 in Norway, accepted to participate in the study. Recommendation about medicines use ranged from 32% (heavy legs) to 71% (back pain) in Serbia and from 3% (heavy legs) to 92% (constipation) in Norway. Several pharmacists' recommendations on medicines and supplements use were inappropriate. Recommendation about non-pharmacological treatments ranged from 11% (nausea) to 50% (heavy legs) in Serbia and from 12% (constipation) to 63% (cold) in Norway. Approximately 12% of the Norwegian and Serbian pharmacists offered referral to a physician as only advice for nausea in pregnancy, indicating a lack of confidence in or knowledge about this common ailment in pregnancy. Key conclusions and implications for practice: Large differences in counselling of pregnant women by pharmacists in Serbia and Norway were observed. Enhancement of pharmacists' knowledge about treatment of common ailments in pregnancy is needed and will enhance pharmacists' role in improving maternal health.
PB  - Elsevier Sci Ltd, Oxford
T2  - Midwifery
T1  - Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway
VL  - 40
SP  - 79
EP  - 86
DO  - 10.1016/j.midw.2016.06.003
ER  - 

@article{
author = "Odalović, Marina and Milanković, Silje and Holst, Lone and Nordeng, Hedvig and Heitmann, Kristine and Tasić, Ljiljana",
year = "2016",
abstract = "Objectives: To describe, compare and evaluate whether pharmacists in two European countries, Serbia and Norway, give appropriate counselling for common ailments in pregnancy. Design: A cross sectional, web-based study. Participants and Settings: A study was conducted among Serbian and Norwegian pharmacists during two four-month study periods in 2012 respectively 2014. Participants were recruited through postal and electronic invitation facilitated by several pharmacy chains. Participation in the study was anonymous and voluntary. Measurement instrument: Pharmacists were presented with the questionnaire that included five scenarios (back pain, heavy legs, nausea, cold and constipation in pregnancy) and were asked to give their advice about use of medicines, supplements (e.g. herbal products, vitamins, minerals), non-pharmacological treatment and referral to physician in each condition. Findings: In total, 276 pharmacists, 119 in Serbia and 157 in Norway, accepted to participate in the study. Recommendation about medicines use ranged from 32% (heavy legs) to 71% (back pain) in Serbia and from 3% (heavy legs) to 92% (constipation) in Norway. Several pharmacists' recommendations on medicines and supplements use were inappropriate. Recommendation about non-pharmacological treatments ranged from 11% (nausea) to 50% (heavy legs) in Serbia and from 12% (constipation) to 63% (cold) in Norway. Approximately 12% of the Norwegian and Serbian pharmacists offered referral to a physician as only advice for nausea in pregnancy, indicating a lack of confidence in or knowledge about this common ailment in pregnancy. Key conclusions and implications for practice: Large differences in counselling of pregnant women by pharmacists in Serbia and Norway were observed. Enhancement of pharmacists' knowledge about treatment of common ailments in pregnancy is needed and will enhance pharmacists' role in improving maternal health.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Midwifery",
title = "Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway",
volume = "40",
pages = "79-86",
doi = "10.1016/j.midw.2016.06.003"
}

Odalović, M., Milanković, S., Holst, L., Nordeng, H., Heitmann, K.,& Tasić, L.. (2016). Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway. in Midwifery
Elsevier Sci Ltd, Oxford., 40, 79-86.
https://doi.org/10.1016/j.midw.2016.06.003

Odalović M, Milanković S, Holst L, Nordeng H, Heitmann K, Tasić L. Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway. in Midwifery. 2016;40:79-86.
doi:10.1016/j.midw.2016.06.003 .

Odalović, Marina, Milanković, Silje, Holst, Lone, Nordeng, Hedvig, Heitmann, Kristine, Tasić, Ljiljana, "Pharmacists counselling of pregnant women: Web-based, comparative study between Serbia and Norway" in Midwifery, 40 (2016):79-86,
https://doi.org/10.1016/j.midw.2016.06.003 . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Tadić, Ivana
AU  - Lakić, Dragana
AU  - Nordeng, Hedvig
AU  - Lupattelli, Angela
AU  - Tasić, Ljiljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2319
AB  - Background: The Edinburgh Postnatal Depression Scale (EPDS) is well accepted for detecting symptoms of postnatal depression. The aim of this study was to examine psychometric properties and to evaluate structural models of the Serbian translation of EPDS in pregnant and postpartum women. Methods: The original English version of the EPDS was translated into Serbian, and checked by means of back-translation. Data were collected via an anonymous online questionnaire posted on a Serbian website devoted to pregnancy topics. The study sample included 201 women (76 pregnant, 125 postpartum). The internal consistency of the scale was measured by Cronbach's a coefficient. Principal component analysis was used to determine scale dimensions while confirmatory factor analysis was used to evaluate model fit. Findings: Cronbach a coefficient was 0.84 and 0.83 in pregnant and postpartum women, respectively, which indicated good internal consistency of the Serbian EPDS. Three dimensions of the scale were revealed in both groups of women. Goodness of fit indices described good and excellent model in pregnant and postpartum women, respectively. High level of depression symptoms (score > 13) was recorded in 27.6% and 24.8% (p > 0.05) of pregnant and postpartum women, respectively. Moderate level of depression symptoms (score 10-12) was recorded in 21.1% and 16.8% (p > 0.05) of pregnant and postpartum women, respectively. Conclusion: The Serbian translation of the EPDS showed good consistency and good model characteristics in pregnant and postpartum women. However, cut-off values, sensitivity and specificity of the scale should be determined in the further studies with more representative samples of women.
PB  - Elsevier BV
T2  - World Journal of Gastroenterology
T1  - Translation and factor analysis of structural models of Edinburgh Postnatal Depression Scale in Serbian pregnant and postpartum women - Web-based study
VL  - 28
IS  - 3
DO  - 10.1016/j.wombi.2015.01.014
ER  - 

@article{
author = "Odalović, Marina and Tadić, Ivana and Lakić, Dragana and Nordeng, Hedvig and Lupattelli, Angela and Tasić, Ljiljana",
year = "2015",
abstract = "Background: The Edinburgh Postnatal Depression Scale (EPDS) is well accepted for detecting symptoms of postnatal depression. The aim of this study was to examine psychometric properties and to evaluate structural models of the Serbian translation of EPDS in pregnant and postpartum women. Methods: The original English version of the EPDS was translated into Serbian, and checked by means of back-translation. Data were collected via an anonymous online questionnaire posted on a Serbian website devoted to pregnancy topics. The study sample included 201 women (76 pregnant, 125 postpartum). The internal consistency of the scale was measured by Cronbach's a coefficient. Principal component analysis was used to determine scale dimensions while confirmatory factor analysis was used to evaluate model fit. Findings: Cronbach a coefficient was 0.84 and 0.83 in pregnant and postpartum women, respectively, which indicated good internal consistency of the Serbian EPDS. Three dimensions of the scale were revealed in both groups of women. Goodness of fit indices described good and excellent model in pregnant and postpartum women, respectively. High level of depression symptoms (score > 13) was recorded in 27.6% and 24.8% (p > 0.05) of pregnant and postpartum women, respectively. Moderate level of depression symptoms (score 10-12) was recorded in 21.1% and 16.8% (p > 0.05) of pregnant and postpartum women, respectively. Conclusion: The Serbian translation of the EPDS showed good consistency and good model characteristics in pregnant and postpartum women. However, cut-off values, sensitivity and specificity of the scale should be determined in the further studies with more representative samples of women.",
publisher = "Elsevier BV",
journal = "World Journal of Gastroenterology",
title = "Translation and factor analysis of structural models of Edinburgh Postnatal Depression Scale in Serbian pregnant and postpartum women - Web-based study",
volume = "28",
number = "3",
doi = "10.1016/j.wombi.2015.01.014"
}

Odalović, M., Tadić, I., Lakić, D., Nordeng, H., Lupattelli, A.,& Tasić, L.. (2015). Translation and factor analysis of structural models of Edinburgh Postnatal Depression Scale in Serbian pregnant and postpartum women - Web-based study. in World Journal of Gastroenterology
Elsevier BV., 28(3).
https://doi.org/10.1016/j.wombi.2015.01.014

Odalović M, Tadić I, Lakić D, Nordeng H, Lupattelli A, Tasić L. Translation and factor analysis of structural models of Edinburgh Postnatal Depression Scale in Serbian pregnant and postpartum women - Web-based study. in World Journal of Gastroenterology. 2015;28(3).
doi:10.1016/j.wombi.2015.01.014 .

Odalović, Marina, Tadić, Ivana, Lakić, Dragana, Nordeng, Hedvig, Lupattelli, Angela, Tasić, Ljiljana, "Translation and factor analysis of structural models of Edinburgh Postnatal Depression Scale in Serbian pregnant and postpartum women - Web-based study" in World Journal of Gastroenterology, 28, no. 3 (2015),
https://doi.org/10.1016/j.wombi.2015.01.014 . .

TY  - JOUR
AU  - Lupattelli, Angela
AU  - Spigset, Olav
AU  - Bjoernsdottir, Ingunn
AU  - Haemeen-Anttila, Katri
AU  - Mardby, Ann-Charlotte
AU  - Panchaud, Alice
AU  - Juraski, Romana Gjergja
AU  - Rudolf, Gorazd
AU  - Odalović, Marina
AU  - Drozd, Mariola
AU  - Twigg, Michael J.
AU  - Juch, Herbert
AU  - Moretti, Myla E.
AU  - Kennedy, Debra
AU  - Rieutord, Andre
AU  - Zagorodnikova, Ksenia
AU  - Passier, Anneke
AU  - Nordeng, Hedvig
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2397
AB  - BackgroundNo previous studies have explored how closely women follow their psychotropic drug regimens during pregnancy. This study aimed to explore patterns of and factors associated with low adherence to psychotropic medication during pregnancy. MethodsMultinational web-based study was performed in 18 countries in Europe, North America, and Australia. Uniform data collection was ensured via an electronic questionnaire. Pregnant women were eligible to participate. Adherence was measured via the 8-item Morisky Medication Adherence Scale (MMAS-8). The Beliefs about Prescribed Medicines Questionnaire (BMQ-specific), the Edinburgh Postnatal Depression Scale (EPDS), and a numeric rating scale were utilized to measure women's beliefs, depressive symptoms, and antidepressant risk perception, respectively. Participants reporting use of psychotropic medication during pregnancy (n = 160) were included in the analysis. ResultsOn the basis of the MMAS-8, 78 of 160 women (48.8%, 95% CI: 41.1-56.4%) demonstrated low adherence during pregnancy. The rates of low adherence were 51.3% for medication for anxiety, 47.2% for depression, and 42.9% for other psychiatric disorders. Smoking during pregnancy, elevated antidepressant risk perception (risk6), and depressive symptoms were associated with a significant 3.9-, 2.3-, and 2.5-fold increased likelihood of low medication adherence, respectively. Women on psychotropic polytherapy were less likely to demonstrate low adherence. The belief that the benefit of pharmacotherapy outweighed the risks positively correlated (r = .282) with higher medication adherence. ConclusionsApproximately one of two pregnant women using psychotropic medication demonstrated low adherence in pregnancy. Life-style factors, risk perception, depressive symptoms, and individual beliefs are important factors related to adherence to psychotropic medication in pregnancy.
PB  - Wiley, Hoboken
T2  - Depression and Anxiety
T1  - Patterns and factors associated with low adherence to psychotropic medications during pregnancy - A cross-sectional, multinational web-based study
VL  - 32
IS  - 6
SP  - 426
EP  - 436
DO  - 10.1002/da.22352
ER  - 

@article{
author = "Lupattelli, Angela and Spigset, Olav and Bjoernsdottir, Ingunn and Haemeen-Anttila, Katri and Mardby, Ann-Charlotte and Panchaud, Alice and Juraski, Romana Gjergja and Rudolf, Gorazd and Odalović, Marina and Drozd, Mariola and Twigg, Michael J. and Juch, Herbert and Moretti, Myla E. and Kennedy, Debra and Rieutord, Andre and Zagorodnikova, Ksenia and Passier, Anneke and Nordeng, Hedvig",
year = "2015",
abstract = "BackgroundNo previous studies have explored how closely women follow their psychotropic drug regimens during pregnancy. This study aimed to explore patterns of and factors associated with low adherence to psychotropic medication during pregnancy. MethodsMultinational web-based study was performed in 18 countries in Europe, North America, and Australia. Uniform data collection was ensured via an electronic questionnaire. Pregnant women were eligible to participate. Adherence was measured via the 8-item Morisky Medication Adherence Scale (MMAS-8). The Beliefs about Prescribed Medicines Questionnaire (BMQ-specific), the Edinburgh Postnatal Depression Scale (EPDS), and a numeric rating scale were utilized to measure women's beliefs, depressive symptoms, and antidepressant risk perception, respectively. Participants reporting use of psychotropic medication during pregnancy (n = 160) were included in the analysis. ResultsOn the basis of the MMAS-8, 78 of 160 women (48.8%, 95% CI: 41.1-56.4%) demonstrated low adherence during pregnancy. The rates of low adherence were 51.3% for medication for anxiety, 47.2% for depression, and 42.9% for other psychiatric disorders. Smoking during pregnancy, elevated antidepressant risk perception (risk6), and depressive symptoms were associated with a significant 3.9-, 2.3-, and 2.5-fold increased likelihood of low medication adherence, respectively. Women on psychotropic polytherapy were less likely to demonstrate low adherence. The belief that the benefit of pharmacotherapy outweighed the risks positively correlated (r = .282) with higher medication adherence. ConclusionsApproximately one of two pregnant women using psychotropic medication demonstrated low adherence in pregnancy. Life-style factors, risk perception, depressive symptoms, and individual beliefs are important factors related to adherence to psychotropic medication in pregnancy.",
publisher = "Wiley, Hoboken",
journal = "Depression and Anxiety",
title = "Patterns and factors associated with low adherence to psychotropic medications during pregnancy - A cross-sectional, multinational web-based study",
volume = "32",
number = "6",
pages = "426-436",
doi = "10.1002/da.22352"
}

Lupattelli, A., Spigset, O., Bjoernsdottir, I., Haemeen-Anttila, K., Mardby, A., Panchaud, A., Juraski, R. G., Rudolf, G., Odalović, M., Drozd, M., Twigg, M. J., Juch, H., Moretti, M. E., Kennedy, D., Rieutord, A., Zagorodnikova, K., Passier, A.,& Nordeng, H.. (2015). Patterns and factors associated with low adherence to psychotropic medications during pregnancy - A cross-sectional, multinational web-based study. in Depression and Anxiety
Wiley, Hoboken., 32(6), 426-436.
https://doi.org/10.1002/da.22352

Lupattelli A, Spigset O, Bjoernsdottir I, Haemeen-Anttila K, Mardby A, Panchaud A, Juraski RG, Rudolf G, Odalović M, Drozd M, Twigg MJ, Juch H, Moretti ME, Kennedy D, Rieutord A, Zagorodnikova K, Passier A, Nordeng H. Patterns and factors associated with low adherence to psychotropic medications during pregnancy - A cross-sectional, multinational web-based study. in Depression and Anxiety. 2015;32(6):426-436.
doi:10.1002/da.22352 .

Lupattelli, Angela, Spigset, Olav, Bjoernsdottir, Ingunn, Haemeen-Anttila, Katri, Mardby, Ann-Charlotte, Panchaud, Alice, Juraski, Romana Gjergja, Rudolf, Gorazd, Odalović, Marina, Drozd, Mariola, Twigg, Michael J., Juch, Herbert, Moretti, Myla E., Kennedy, Debra, Rieutord, Andre, Zagorodnikova, Ksenia, Passier, Anneke, Nordeng, Hedvig, "Patterns and factors associated with low adherence to psychotropic medications during pregnancy - A cross-sectional, multinational web-based study" in Depression and Anxiety, 32, no. 6 (2015):426-436,
https://doi.org/10.1002/da.22352 . .

TY  - JOUR
AU  - Lupattelli, Angela
AU  - Spigset, Olav
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Mardby, Ann-Charlotte
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Haemeen-Anttila, Katri
AU  - Rieutord, Andre
AU  - Juraski, R. Gjergja
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Passier, Anneke
AU  - Bjoernsdottir, Ingunn
AU  - Nordeng, Hedvig
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2154
AB  - Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.
PB  - BMJ PUBLISHING GROUP, LONDON
T2  - BMJ Open
T1  - Medication use in pregnancy: a cross-sectional, multinational web-based study
VL  - 4
IS  - 2
DO  - 10.1136/bmjopen-2013-004365
ER  - 

@article{
author = "Lupattelli, Angela and Spigset, Olav and Twigg, Michael J. and Zagorodnikova, Ksenia and Mardby, Ann-Charlotte and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Haemeen-Anttila, Katri and Rieutord, Andre and Juraski, R. Gjergja and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Passier, Anneke and Bjoernsdottir, Ingunn and Nordeng, Hedvig",
year = "2014",
abstract = "Objectives Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. This study aimed to examine patterns and factors associated with medications use in pregnancy from a multinational perspective, with emphasis on type of medication utilised and indication for use. Design Cross-sectional, web-based study performed within the period from 1 October 2011 to 29 February 2012. Uniform collection of drug utilisation data was performed via an anonymous online questionnaire. Setting Multinational study in Europe (Western, Northern and Eastern), North and South America and Australia. Participants Pregnant women and new mothers with children less than 1year of age. Primary and secondary outcome measures Prevalence of and factors associated with medication use for acute/short-term illnesses, chronic/long-term disorders and over-the-counter (OTC) medication use. Results The study population included 9459 women, of which 81.2% reported use of at least one medication (prescribed or OTC) during pregnancy. Overall, OTC medication use occurred in 66.9% of the pregnancies, whereas 68.4% and 17% of women reported use of at least one medication for treatment of acute/short-term illnesses and chronic/long-term disorders, respectively. The extent of self-reported medicated illnesses and types of medication used by indication varied across regions, especially in relation to urinary tract infections, depression or OTC nasal sprays. Women with higher age or lower educational level, housewives or women with an unplanned pregnancy were those most often reporting use of medication for chronic/long-term disorders. Immigrant women in Western (adjusted OR (aOR): 0.55, 95% CI 0.34 to 0.87) and Northern Europe (aOR: 0.50, 95% CI 0.31 to 0.83) were less likely to report use of medication for chronic/long-term disorders during pregnancy than non-immigrants. Conclusions In this study, the majority of women in Europe, North America, South America and Australia used at least one medication during pregnancy. There was a substantial inter-region variability in the types of medication used.",
publisher = "BMJ PUBLISHING GROUP, LONDON",
journal = "BMJ Open",
title = "Medication use in pregnancy: a cross-sectional, multinational web-based study",
volume = "4",
number = "2",
doi = "10.1136/bmjopen-2013-004365"
}

Lupattelli, A., Spigset, O., Twigg, M. J., Zagorodnikova, K., Mardby, A., Moretti, M. E., Drozd, M., Panchaud, A., Haemeen-Anttila, K., Rieutord, A., Juraski, R. G., Odalović, M., Kennedy, D., Rudolf, G., Juch, H., Passier, A., Bjoernsdottir, I.,& Nordeng, H.. (2014). Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open
BMJ PUBLISHING GROUP, LONDON., 4(2).
https://doi.org/10.1136/bmjopen-2013-004365

Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mardby A, Moretti ME, Drozd M, Panchaud A, Haemeen-Anttila K, Rieutord A, Juraski RG, Odalović M, Kennedy D, Rudolf G, Juch H, Passier A, Bjoernsdottir I, Nordeng H. Medication use in pregnancy: a cross-sectional, multinational web-based study. in BMJ Open. 2014;4(2).
doi:10.1136/bmjopen-2013-004365 .

Lupattelli, Angela, Spigset, Olav, Twigg, Michael J., Zagorodnikova, Ksenia, Mardby, Ann-Charlotte, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Haemeen-Anttila, Katri, Rieutord, Andre, Juraski, R. Gjergja, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Passier, Anneke, Bjoernsdottir, Ingunn, Nordeng, Hedvig, "Medication use in pregnancy: a cross-sectional, multinational web-based study" in BMJ Open, 4, no. 2 (2014),
https://doi.org/10.1136/bmjopen-2013-004365 . .

TY  - CONF
AU  - Lupattelli, Angela
AU  - Spigset, Olav
AU  - Twigg, Michael J.
AU  - Zagorodnikova, Ksenia
AU  - Mardby, Ann-Charlotte
AU  - Moretti, Myla E.
AU  - Drozd, Mariola
AU  - Panchaud, Alice
AU  - Haemeen-Anttila, Katri
AU  - Rieutord, Andre
AU  - Gjergia, Romana
AU  - Odalović, Marina
AU  - Kennedy, Debra
AU  - Rudolf, Gorazd
AU  - Juch, Herbert
AU  - Passier, Anneke
AU  - Bjoernsdottir, Ingunn
AU  - Nordeng, Hedvig
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1892
PB  - John Wiley & Sons, Ltd
C3  - Pharmacoepidemiology and Drug Safety
T1  - Medication Use during Pregnancy: A Multinational Perspective
VL  - 22
IS  - s1
SP  - 75
EP  - 75
DO  - 10.1002/pds.3512
ER  - 

@conference{
author = "Lupattelli, Angela and Spigset, Olav and Twigg, Michael J. and Zagorodnikova, Ksenia and Mardby, Ann-Charlotte and Moretti, Myla E. and Drozd, Mariola and Panchaud, Alice and Haemeen-Anttila, Katri and Rieutord, Andre and Gjergia, Romana and Odalović, Marina and Kennedy, Debra and Rudolf, Gorazd and Juch, Herbert and Passier, Anneke and Bjoernsdottir, Ingunn and Nordeng, Hedvig",
year = "2013",
publisher = "John Wiley & Sons, Ltd",
journal = "Pharmacoepidemiology and Drug Safety",
title = "Medication Use during Pregnancy: A Multinational Perspective",
volume = "22",
number = "s1",
pages = "75-75",
doi = "10.1002/pds.3512"
}

Lupattelli, A., Spigset, O., Twigg, M. J., Zagorodnikova, K., Mardby, A., Moretti, M. E., Drozd, M., Panchaud, A., Haemeen-Anttila, K., Rieutord, A., Gjergia, R., Odalović, M., Kennedy, D., Rudolf, G., Juch, H., Passier, A., Bjoernsdottir, I.,& Nordeng, H.. (2013). Medication Use during Pregnancy: A Multinational Perspective. in Pharmacoepidemiology and Drug Safety
John Wiley & Sons, Ltd., 22(s1), 75-75.
https://doi.org/10.1002/pds.3512

Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mardby A, Moretti ME, Drozd M, Panchaud A, Haemeen-Anttila K, Rieutord A, Gjergia R, Odalović M, Kennedy D, Rudolf G, Juch H, Passier A, Bjoernsdottir I, Nordeng H. Medication Use during Pregnancy: A Multinational Perspective. in Pharmacoepidemiology and Drug Safety. 2013;22(s1):75-75.
doi:10.1002/pds.3512 .

Lupattelli, Angela, Spigset, Olav, Twigg, Michael J., Zagorodnikova, Ksenia, Mardby, Ann-Charlotte, Moretti, Myla E., Drozd, Mariola, Panchaud, Alice, Haemeen-Anttila, Katri, Rieutord, Andre, Gjergia, Romana, Odalović, Marina, Kennedy, Debra, Rudolf, Gorazd, Juch, Herbert, Passier, Anneke, Bjoernsdottir, Ingunn, Nordeng, Hedvig, "Medication Use during Pregnancy: A Multinational Perspective" in Pharmacoepidemiology and Drug Safety, 22, no. s1 (2013):75-75,
https://doi.org/10.1002/pds.3512 . .

TY  - JOUR
AU  - Odalović, Marina
AU  - Vezmar-Kovačević, Sandra
AU  - Nordeng, Hedvig
AU  - Ilić, Katarina
AU  - Sabo, Ana
AU  - Tasić, Ljiljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1987
AB  - Background Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy. Objectives To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of pregnancy. To examine whether prescription and over-the-counter (OTC) medication use in the 6 months before pregnancy had an impact on medication use in pregnancy. Setting Six maternity care units and five community pharmacies. Method Data were collected using a specially designed self-reported questionnaire during the period March 2009-March 2010. Logistic regression was used to identify factors associated with medication use. Main outcome measure Adjusted odds ratios (aOR) and 95 % confidence intervals (CI) were used as association measures. Results A total of 236 women were included in the analysis. After controlling for maternal characteristics, parity of more than one was associated with lower prescription medication use in pregnancy (aOR 0.46; 95 % CI 0.22-0.93), higher household income with higher OTC medication use before pregnancy (aOR 3.13; 95 % CI 1.22-8.00), and miscarriage with higher C and D Food and Drug Administration (FDA) risk category medication use in pregnancy (aOR 3.65; 95 % CI 1.30-10.25). Prescription medication use before pregnancy was associated with higher prescription medication use in pregnancy (aOR 2.49; 95 % CI 1.12-5.52), OTC medication use before pregnancy with higher OTC medication use in pregnancy (aOR 35.95; 95 % CI 7.95-162.49), and C and D FDA risk category medication use before pregnancy with the same category medication use in pregnancy (aOR 3.54; 95 % CI 1.23-10.17). Conclusion Different maternal characteristics were shown as predictors of medication use before and during pregnancy. However, medication use before pregnancy was shown as the most important predicting factor for the medication use in pregnancy.
PB  - Springer, Dordrecht
T2  - International Journal of Clinical Pharmacy
T1  - Predictors of the use of medications before and during pregnancy
VL  - 35
IS  - 3
SP  - 408
EP  - 416
DO  - 10.1007/s11096-013-9750-7
ER  - 

@article{
author = "Odalović, Marina and Vezmar-Kovačević, Sandra and Nordeng, Hedvig and Ilić, Katarina and Sabo, Ana and Tasić, Ljiljana",
year = "2013",
abstract = "Background Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy. Objectives To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of pregnancy. To examine whether prescription and over-the-counter (OTC) medication use in the 6 months before pregnancy had an impact on medication use in pregnancy. Setting Six maternity care units and five community pharmacies. Method Data were collected using a specially designed self-reported questionnaire during the period March 2009-March 2010. Logistic regression was used to identify factors associated with medication use. Main outcome measure Adjusted odds ratios (aOR) and 95 % confidence intervals (CI) were used as association measures. Results A total of 236 women were included in the analysis. After controlling for maternal characteristics, parity of more than one was associated with lower prescription medication use in pregnancy (aOR 0.46; 95 % CI 0.22-0.93), higher household income with higher OTC medication use before pregnancy (aOR 3.13; 95 % CI 1.22-8.00), and miscarriage with higher C and D Food and Drug Administration (FDA) risk category medication use in pregnancy (aOR 3.65; 95 % CI 1.30-10.25). Prescription medication use before pregnancy was associated with higher prescription medication use in pregnancy (aOR 2.49; 95 % CI 1.12-5.52), OTC medication use before pregnancy with higher OTC medication use in pregnancy (aOR 35.95; 95 % CI 7.95-162.49), and C and D FDA risk category medication use before pregnancy with the same category medication use in pregnancy (aOR 3.54; 95 % CI 1.23-10.17). Conclusion Different maternal characteristics were shown as predictors of medication use before and during pregnancy. However, medication use before pregnancy was shown as the most important predicting factor for the medication use in pregnancy.",
publisher = "Springer, Dordrecht",
journal = "International Journal of Clinical Pharmacy",
title = "Predictors of the use of medications before and during pregnancy",
volume = "35",
number = "3",
pages = "408-416",
doi = "10.1007/s11096-013-9750-7"
}

Odalović, M., Vezmar-Kovačević, S., Nordeng, H., Ilić, K., Sabo, A.,& Tasić, L.. (2013). Predictors of the use of medications before and during pregnancy. in International Journal of Clinical Pharmacy
Springer, Dordrecht., 35(3), 408-416.
https://doi.org/10.1007/s11096-013-9750-7

Odalović M, Vezmar-Kovačević S, Nordeng H, Ilić K, Sabo A, Tasić L. Predictors of the use of medications before and during pregnancy. in International Journal of Clinical Pharmacy. 2013;35(3):408-416.
doi:10.1007/s11096-013-9750-7 .

Odalović, Marina, Vezmar-Kovačević, Sandra, Nordeng, Hedvig, Ilić, Katarina, Sabo, Ana, Tasić, Ljiljana, "Predictors of the use of medications before and during pregnancy" in International Journal of Clinical Pharmacy, 35, no. 3 (2013):408-416,
https://doi.org/10.1007/s11096-013-9750-7 . .