TY  - JOUR
AU  - Bajić, Vladan
AU  - Potparević, Biljana
AU  - Živković, Lada
AU  - Isenović, Esma
AU  - Arendt, Thomas
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2430
AB  - Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimer's disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to "core cell cycle regulators" are also key regulators in cell division. Functions of these cell cycle regulators include neuronal migration, axonal elongation, axon pruning, dendrite morphogenesis and synaptic maturation and plasticity. In this review, we focus on cohesion and cohesion related proteins in reference to their neuronal functions and how impaired centromere/cohesion dynamics may connect cell cycle dysfunction to aneuploidy in AD.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Neuroscience and Biobehavioral Reviews
T1  - Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability
VL  - 55
SP  - 365
EP  - 374
DO  - 10.1016/j.neubiorev.2015.05.010
ER  - 

@article{
author = "Bajić, Vladan and Potparević, Biljana and Živković, Lada and Isenović, Esma and Arendt, Thomas",
year = "2015",
abstract = "Neurons are postmitotic cells that are in permanent cell cycle arrest. However, components of the cell cycle machinery that are expressed in Alzheimer's disease (AD) neurons are showing features of a cycling cell and those attributed to a postmitotic cell as well. Furthermore, the unique physiological operations taking place in neurons, ascribed to "core cell cycle regulators" are also key regulators in cell division. Functions of these cell cycle regulators include neuronal migration, axonal elongation, axon pruning, dendrite morphogenesis and synaptic maturation and plasticity. In this review, we focus on cohesion and cohesion related proteins in reference to their neuronal functions and how impaired centromere/cohesion dynamics may connect cell cycle dysfunction to aneuploidy in AD.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Neuroscience and Biobehavioral Reviews",
title = "Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability",
volume = "55",
pages = "365-374",
doi = "10.1016/j.neubiorev.2015.05.010"
}

Bajić, V., Potparević, B., Živković, L., Isenović, E.,& Arendt, T.. (2015). Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability. in Neuroscience and Biobehavioral Reviews
Pergamon-Elsevier Science Ltd, Oxford., 55, 365-374.
https://doi.org/10.1016/j.neubiorev.2015.05.010

Bajić V, Potparević B, Živković L, Isenović E, Arendt T. Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability. in Neuroscience and Biobehavioral Reviews. 2015;55:365-374.
doi:10.1016/j.neubiorev.2015.05.010 .

Bajić, Vladan, Potparević, Biljana, Živković, Lada, Isenović, Esma, Arendt, Thomas, "Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability" in Neuroscience and Biobehavioral Reviews, 55 (2015):365-374,
https://doi.org/10.1016/j.neubiorev.2015.05.010 . .