TY  - JOUR
AU  - Vasić, Vesna
AU  - Živanović, MA
AU  - Čakar, Mira
AU  - Savić, Jasmina Z.
AU  - Nedeljković, Jovan M.
AU  - Bugarčić, Živadin
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/591
AB  - The reaction mechanism and thermodynamic parameters of the complex formation between [PdCl(dien)](+) and sulfur-containing ligands L-cysteine and glutathione (GSH) were investigated in the presence of sodium dodecyl sulfate micelles in the pH range 0.5-3.5. The reaction rates were determined under pseudo-first-order conditions (ligand in excess) in the temperature range 276-299 K by using the stopped-flow technique. A reaction mechanism was proposed that consisted of at least two parallel paths involving protonated and zwitterionic forms of thiols. The pH effects on reaction rate were interpreted in terms of the electrostatic interactions between the negatively charged micelle surface and different ionic forms of the ligand species. The calculation of pH-dependent activation parameters (Delta H-not equal and Delta S-not equal) revealed the considerable catalytic effects on the rate of complexation. The entropy of activation is strongly negative in the presence and absence of micelles, which is compatible with an associative reaction mechanism. Copyright
PB  - John Wiley & Sons Ltd, Chichester
T2  - Journal of Physical Organic Chemistry
T1  - Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles
VL  - 18
IS  - 5
SP  - 441
EP  - 447
DO  - 10.1002/poc.880
ER  - 

@article{
author = "Vasić, Vesna and Živanović, MA and Čakar, Mira and Savić, Jasmina Z. and Nedeljković, Jovan M. and Bugarčić, Živadin",
year = "2005",
abstract = "The reaction mechanism and thermodynamic parameters of the complex formation between [PdCl(dien)](+) and sulfur-containing ligands L-cysteine and glutathione (GSH) were investigated in the presence of sodium dodecyl sulfate micelles in the pH range 0.5-3.5. The reaction rates were determined under pseudo-first-order conditions (ligand in excess) in the temperature range 276-299 K by using the stopped-flow technique. A reaction mechanism was proposed that consisted of at least two parallel paths involving protonated and zwitterionic forms of thiols. The pH effects on reaction rate were interpreted in terms of the electrostatic interactions between the negatively charged micelle surface and different ionic forms of the ligand species. The calculation of pH-dependent activation parameters (Delta H-not equal and Delta S-not equal) revealed the considerable catalytic effects on the rate of complexation. The entropy of activation is strongly negative in the presence and absence of micelles, which is compatible with an associative reaction mechanism. Copyright",
publisher = "John Wiley & Sons Ltd, Chichester",
journal = "Journal of Physical Organic Chemistry",
title = "Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles",
volume = "18",
number = "5",
pages = "441-447",
doi = "10.1002/poc.880"
}

Vasić, V., Živanović, M., Čakar, M., Savić, J. Z., Nedeljković, J. M.,& Bugarčić, Ž.. (2005). Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles. in Journal of Physical Organic Chemistry
John Wiley & Sons Ltd, Chichester., 18(5), 441-447.
https://doi.org/10.1002/poc.880

Vasić V, Živanović M, Čakar M, Savić JZ, Nedeljković JM, Bugarčić Ž. Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles. in Journal of Physical Organic Chemistry. 2005;18(5):441-447.
doi:10.1002/poc.880 .

Vasić, Vesna, Živanović, MA, Čakar, Mira, Savić, Jasmina Z., Nedeljković, Jovan M., Bugarčić, Živadin, "Influence of acidity on the reaction between [PdCl(dien)](+) and L-cysteine or glutathione in the presence of sodium dodecyl sulfate micelles" in Journal of Physical Organic Chemistry, 18, no. 5 (2005):441-447,
https://doi.org/10.1002/poc.880 . .

TY  - CONF
AU  - Čakar, Mira
AU  - Vasić, Vesna
AU  - Savić, Jasmina Z.
AU  - Bugarčić, Živadin
PY  - 2002
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/384
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - The spectrophotometric investigation of the reaction of [Pd(dien)Cl]+ with amino acids
T1  - Spektrofotometrijsko ispitivanje reakcije [Pd(dien)Cl]+ sa amino kiselinama
VL  - 52
IS  - 4
SP  - 506
EP  - 507
UR  - https://hdl.handle.net/21.15107/rcub_farfar_384
ER  - 

@conference{
author = "Čakar, Mira and Vasić, Vesna and Savić, Jasmina Z. and Bugarčić, Živadin",
year = "2002",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "The spectrophotometric investigation of the reaction of [Pd(dien)Cl]+ with amino acids, Spektrofotometrijsko ispitivanje reakcije [Pd(dien)Cl]+ sa amino kiselinama",
volume = "52",
number = "4",
pages = "506-507",
url = "https://hdl.handle.net/21.15107/rcub_farfar_384"
}

Čakar, M., Vasić, V., Savić, J. Z.,& Bugarčić, Ž.. (2002). The spectrophotometric investigation of the reaction of [Pd(dien)Cl]+ with amino acids. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 52(4), 506-507.
https://hdl.handle.net/21.15107/rcub_farfar_384

Čakar M, Vasić V, Savić JZ, Bugarčić Ž. The spectrophotometric investigation of the reaction of [Pd(dien)Cl]+ with amino acids. in Arhiv za farmaciju. 2002;52(4):506-507.
https://hdl.handle.net/21.15107/rcub_farfar_384 .

Čakar, Mira, Vasić, Vesna, Savić, Jasmina Z., Bugarčić, Živadin, "The spectrophotometric investigation of the reaction of [Pd(dien)Cl]+ with amino acids" in Arhiv za farmaciju, 52, no. 4 (2002):506-507,
https://hdl.handle.net/21.15107/rcub_farfar_384 .