TY  - JOUR
AU  - Peruničić-Peković, Gordana
AU  - Rasić, Zorica
AU  - Plješa, Steva
AU  - Šobajić, Slađana
AU  - Đuričić, Ivana
AU  - Maletić, Radojka
AU  - Ristić-Medić, Danijela K.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/990
AB  - Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.
PB  - Wiley, Hoboken
T2  - Nephrology
T1  - Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients
VL  - 12
IS  - 4
SP  - 331
EP  - 336
DO  - 10.1111/j.1440-1797.2007.00777.x
ER  - 

@article{
author = "Peruničić-Peković, Gordana and Rasić, Zorica and Plješa, Steva and Šobajić, Slađana and Đuričić, Ivana and Maletić, Radojka and Ristić-Medić, Danijela K.",
year = "2007",
abstract = "Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.",
publisher = "Wiley, Hoboken",
journal = "Nephrology",
title = "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients",
volume = "12",
number = "4",
pages = "331-336",
doi = "10.1111/j.1440-1797.2007.00777.x"
}

Peruničić-Peković, G., Rasić, Z., Plješa, S., Šobajić, S., Đuričić, I., Maletić, R.,& Ristić-Medić, D. K.. (2007). Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology
Wiley, Hoboken., 12(4), 331-336.
https://doi.org/10.1111/j.1440-1797.2007.00777.x

Peruničić-Peković G, Rasić Z, Plješa S, Šobajić S, Đuričić I, Maletić R, Ristić-Medić DK. Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology. 2007;12(4):331-336.
doi:10.1111/j.1440-1797.2007.00777.x .

Peruničić-Peković, Gordana, Rasić, Zorica, Plješa, Steva, Šobajić, Slađana, Đuričić, Ivana, Maletić, Radojka, Ristić-Medić, Danijela K., "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients" in Nephrology, 12, no. 4 (2007):331-336,
https://doi.org/10.1111/j.1440-1797.2007.00777.x . .

TY  - JOUR
AU  - Đuričić, Ivana
AU  - Šobajić, Slađana
AU  - Peruničić-Peković, Gordana
AU  - Stojanov, Marina
AU  - Rasić, Zorica
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/966
AB  - The population of Serbia is characterized by very low fish intake and a similarly inadequate intake of other natural dietary sources of n-3 fatty acids (FAs). On the other hand, the use of fish oil dietary supplements has increased as well as the number of different commercially available products with fish oil. The effect of fish oil supplement use under real-life conditions on the erythrocyte total FA profile was investigated in this study. Fifteen middle-aged participants without acute health problems but with slightly increased body weight and mild hyperlipiderma were chosen as representatives of the average fish oil supplement consumers in Serbia. For 8, weeks participants were supplemented with fish oil in doses that are commonly used among supplement consumers: 2 fish oil capsules per day, each with a declared content of 180 mg eicosapentaenoic acid (20:50) and 120 mg docosahexacnoic acid (22:60). Erythrocyte lipids were extracted and then analyzed for FA composition by gas chromatography. A significant decrease was observed in oleic and 20:3n9 FAs (P  lt  .05), whereas an increase in eicosapentaenoic acid (0.8 +/- 0.17 to 1.1 +/- 0.59) and docosahexaenoic acid (2.7 +/- 0.87 to 3.5 +/- 1.09) was noted. The ratio of n-6 to n-3 FAs significantly decreased after fish oil supplementation (P  lt .05). Our findings support the practice of moderate fish oil supplement use in the middle-aged slightly overweight and hypercholesterolemic individuals based on its effect on erythrocyte total FA profile.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Nutrition Research
T1  - Consumption of fish oil supplement alters erythrocyte fatty acid composition in overweight, hypercholesterolemic, middle-aged Serbians
VL  - 27
IS  - 9
SP  - 529
EP  - 534
DO  - 10.1016/j.nutres.2007.06.013
ER  - 

@article{
author = "Đuričić, Ivana and Šobajić, Slađana and Peruničić-Peković, Gordana and Stojanov, Marina and Rasić, Zorica",
year = "2007",
abstract = "The population of Serbia is characterized by very low fish intake and a similarly inadequate intake of other natural dietary sources of n-3 fatty acids (FAs). On the other hand, the use of fish oil dietary supplements has increased as well as the number of different commercially available products with fish oil. The effect of fish oil supplement use under real-life conditions on the erythrocyte total FA profile was investigated in this study. Fifteen middle-aged participants without acute health problems but with slightly increased body weight and mild hyperlipiderma were chosen as representatives of the average fish oil supplement consumers in Serbia. For 8, weeks participants were supplemented with fish oil in doses that are commonly used among supplement consumers: 2 fish oil capsules per day, each with a declared content of 180 mg eicosapentaenoic acid (20:50) and 120 mg docosahexacnoic acid (22:60). Erythrocyte lipids were extracted and then analyzed for FA composition by gas chromatography. A significant decrease was observed in oleic and 20:3n9 FAs (P  lt  .05), whereas an increase in eicosapentaenoic acid (0.8 +/- 0.17 to 1.1 +/- 0.59) and docosahexaenoic acid (2.7 +/- 0.87 to 3.5 +/- 1.09) was noted. The ratio of n-6 to n-3 FAs significantly decreased after fish oil supplementation (P  lt .05). Our findings support the practice of moderate fish oil supplement use in the middle-aged slightly overweight and hypercholesterolemic individuals based on its effect on erythrocyte total FA profile.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Nutrition Research",
title = "Consumption of fish oil supplement alters erythrocyte fatty acid composition in overweight, hypercholesterolemic, middle-aged Serbians",
volume = "27",
number = "9",
pages = "529-534",
doi = "10.1016/j.nutres.2007.06.013"
}

Đuričić, I., Šobajić, S., Peruničić-Peković, G., Stojanov, M.,& Rasić, Z.. (2007). Consumption of fish oil supplement alters erythrocyte fatty acid composition in overweight, hypercholesterolemic, middle-aged Serbians. in Nutrition Research
Pergamon-Elsevier Science Ltd, Oxford., 27(9), 529-534.
https://doi.org/10.1016/j.nutres.2007.06.013

Đuričić I, Šobajić S, Peruničić-Peković G, Stojanov M, Rasić Z. Consumption of fish oil supplement alters erythrocyte fatty acid composition in overweight, hypercholesterolemic, middle-aged Serbians. in Nutrition Research. 2007;27(9):529-534.
doi:10.1016/j.nutres.2007.06.013 .

Đuričić, Ivana, Šobajić, Slađana, Peruničić-Peković, Gordana, Stojanov, Marina, Rasić, Zorica, "Consumption of fish oil supplement alters erythrocyte fatty acid composition in overweight, hypercholesterolemic, middle-aged Serbians" in Nutrition Research, 27, no. 9 (2007):529-534,
https://doi.org/10.1016/j.nutres.2007.06.013 . .

TY  - CONF
AU  - Peruničić-Peković, Gordana
AU  - Rasić, Z.
AU  - Plješa, Steva
AU  - Šobajić, Slađana
AU  - Đuričić, Ivana
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/822
PB  - Elsevier Ireland Ltd, Clare
C3  - Atherosclerosis Supplements
T1  - The effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients
VL  - 7
IS  - 3
SP  - 450
EP  - 450
DO  - 10.1016/S1567-5688(06)81821-0
ER  - 

@conference{
author = "Peruničić-Peković, Gordana and Rasić, Z. and Plješa, Steva and Šobajić, Slađana and Đuričić, Ivana",
year = "2006",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Atherosclerosis Supplements",
title = "The effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients",
volume = "7",
number = "3",
pages = "450-450",
doi = "10.1016/S1567-5688(06)81821-0"
}

Peruničić-Peković, G., Rasić, Z., Plješa, S., Šobajić, S.,& Đuričić, I.. (2006). The effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients. in Atherosclerosis Supplements
Elsevier Ireland Ltd, Clare., 7(3), 450-450.
https://doi.org/10.1016/S1567-5688(06)81821-0

Peruničić-Peković G, Rasić Z, Plješa S, Šobajić S, Đuričić I. The effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients. in Atherosclerosis Supplements. 2006;7(3):450-450.
doi:10.1016/S1567-5688(06)81821-0 .

Peruničić-Peković, Gordana, Rasić, Z., Plješa, Steva, Šobajić, Slađana, Đuričić, Ivana, "The effect of n-3 fatty acids on nutritional status and inflammatory markers in hemodialysis patients" in Atherosclerosis Supplements, 7, no. 3 (2006):450-450,
https://doi.org/10.1016/S1567-5688(06)81821-0 . .

TY  - CONF
AU  - Peruničić-Peković, Gordana
AU  - Rasić, Zorica
AU  - Plješa, Steva
AU  - Šobajić, Slađana
AU  - Đuričić, Ivana
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/777
PB  - Oxford Univ Press, Oxford
C3  - Nephrology Dialysis Transplantation
T1  - Polyunsaturated fatty acids in cell membranes of erythrocytes, nutritional status and dietary intervention in hemodialysis patients
VL  - 21
SP  - 458
EP  - 458
UR  - https://hdl.handle.net/21.15107/rcub_farfar_777
ER  - 

@conference{
author = "Peruničić-Peković, Gordana and Rasić, Zorica and Plješa, Steva and Šobajić, Slađana and Đuričić, Ivana",
year = "2006",
publisher = "Oxford Univ Press, Oxford",
journal = "Nephrology Dialysis Transplantation",
title = "Polyunsaturated fatty acids in cell membranes of erythrocytes, nutritional status and dietary intervention in hemodialysis patients",
volume = "21",
pages = "458-458",
url = "https://hdl.handle.net/21.15107/rcub_farfar_777"
}

Peruničić-Peković, G., Rasić, Z., Plješa, S., Šobajić, S.,& Đuričić, I.. (2006). Polyunsaturated fatty acids in cell membranes of erythrocytes, nutritional status and dietary intervention in hemodialysis patients. in Nephrology Dialysis Transplantation
Oxford Univ Press, Oxford., 21, 458-458.
https://hdl.handle.net/21.15107/rcub_farfar_777

Peruničić-Peković G, Rasić Z, Plješa S, Šobajić S, Đuričić I. Polyunsaturated fatty acids in cell membranes of erythrocytes, nutritional status and dietary intervention in hemodialysis patients. in Nephrology Dialysis Transplantation. 2006;21:458-458.
https://hdl.handle.net/21.15107/rcub_farfar_777 .

Peruničić-Peković, Gordana, Rasić, Zorica, Plješa, Steva, Šobajić, Slađana, Đuričić, Ivana, "Polyunsaturated fatty acids in cell membranes of erythrocytes, nutritional status and dietary intervention in hemodialysis patients" in Nephrology Dialysis Transplantation, 21 (2006):458-458,
https://hdl.handle.net/21.15107/rcub_farfar_777 .