Jaćević, V., Dumanović, J., Grujić-Milanović, J., Milovanović, Z., Amidžić, L., Vojinović, N., Nežić, L., Marković, B., Dobričić, V., Milosavljević, P., Nepovimova, E.,& Kuča, K.. (2023). Oxidative stress status assessment of rats' brains injury following subacute exposure to K-oximes. in Chemico-biological interactions
Elsevier B.V.., 383, 110658.
https://doi.org/10.1016/j.cbi.2023.110658

Jaćević V, Dumanović J, Grujić-Milanović J, Milovanović Z, Amidžić L, Vojinović N, Nežić L, Marković B, Dobričić V, Milosavljević P, Nepovimova E, Kuča K. Oxidative stress status assessment of rats' brains injury following subacute exposure to K-oximes. in Chemico-biological interactions. 2023;383:110658.
doi:10.1016/j.cbi.2023.110658 .

Jaćević, Vesna, Dumanović, Jelena, Grujić-Milanović, Jelica, Milovanović, Zoran, Amidžić, Ljiljana, Vojinović, Nataša, Nežić, Lana, Marković, Bojan, Dobričić, Vladimir, Milosavljević, Petar, Nepovimova, Eugenie, Kuča, Kamil, "Oxidative stress status assessment of rats' brains injury following subacute exposure to K-oximes" in Chemico-biological interactions, 383 (2023):110658,
https://doi.org/10.1016/j.cbi.2023.110658 . .

TY  - JOUR
AU  - Dobričić, Vladimir
AU  - Jaćević, Vesna
AU  - Vučićević, Jelica
AU  - Nikolić, Katarina
AU  - Vladimirov, Sote
AU  - Čudina, Olivera
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3001
AB  - Soft glucocorticoids are compounds that are biotransformed to inactive and non-toxic metabolites and have fewer side effects than traditional glucocorticoids. A new class of 17-carboxamide steroids has been recently introduced by our group. In this study, local anti-inflammatory activity of these derivatives was evaluated by use of the croton oil-induced ear edema test. Glucocorticoids with the highest maximal edema inhibition (MEI) were pointed out, and the systemic side effects of those with the lowest EC50 values were significantly lower in comparison to dexamethasone. A 3D-QSAR model was created and employed for the design of 27 compounds. By use of the sequential combination of ligand-based and structure-based virtual screening, three compounds were selected from the ChEMBL library and used as a starting point for the design of 15 derivatives. Molecular docking analysis of the designed derivatives with the highest predicted MEI and relative glucocorticoid receptor binding affinity (20, 22, 24-1, 25-1, 27, VS7, VS13, and VS14) confirmed the presence of interactions with the glucocorticoid receptor that are important for the activity.
PB  - Wiley-VCH Verlag GMBH, Weinheim
T2  - Archiv der Pharmazie
T1  - Evaluation of Biological Activity and Computer-Aided Design of New Soft Glucocorticoids
VL  - 350
IS  - 5
DO  - 10.1002/ardp.201600383
ER  - 

@article{
author = "Dobričić, Vladimir and Jaćević, Vesna and Vučićević, Jelica and Nikolić, Katarina and Vladimirov, Sote and Čudina, Olivera",
year = "2017",
abstract = "Soft glucocorticoids are compounds that are biotransformed to inactive and non-toxic metabolites and have fewer side effects than traditional glucocorticoids. A new class of 17-carboxamide steroids has been recently introduced by our group. In this study, local anti-inflammatory activity of these derivatives was evaluated by use of the croton oil-induced ear edema test. Glucocorticoids with the highest maximal edema inhibition (MEI) were pointed out, and the systemic side effects of those with the lowest EC50 values were significantly lower in comparison to dexamethasone. A 3D-QSAR model was created and employed for the design of 27 compounds. By use of the sequential combination of ligand-based and structure-based virtual screening, three compounds were selected from the ChEMBL library and used as a starting point for the design of 15 derivatives. Molecular docking analysis of the designed derivatives with the highest predicted MEI and relative glucocorticoid receptor binding affinity (20, 22, 24-1, 25-1, 27, VS7, VS13, and VS14) confirmed the presence of interactions with the glucocorticoid receptor that are important for the activity.",
publisher = "Wiley-VCH Verlag GMBH, Weinheim",
journal = "Archiv der Pharmazie",
title = "Evaluation of Biological Activity and Computer-Aided Design of New Soft Glucocorticoids",
volume = "350",
number = "5",
doi = "10.1002/ardp.201600383"
}

Dobričić, V., Jaćević, V., Vučićević, J., Nikolić, K., Vladimirov, S.,& Čudina, O.. (2017). Evaluation of Biological Activity and Computer-Aided Design of New Soft Glucocorticoids. in Archiv der Pharmazie
Wiley-VCH Verlag GMBH, Weinheim., 350(5).
https://doi.org/10.1002/ardp.201600383

Dobričić V, Jaćević V, Vučićević J, Nikolić K, Vladimirov S, Čudina O. Evaluation of Biological Activity and Computer-Aided Design of New Soft Glucocorticoids. in Archiv der Pharmazie. 2017;350(5).
doi:10.1002/ardp.201600383 .

Dobričić, Vladimir, Jaćević, Vesna, Vučićević, Jelica, Nikolić, Katarina, Vladimirov, Sote, Čudina, Olivera, "Evaluation of Biological Activity and Computer-Aided Design of New Soft Glucocorticoids" in Archiv der Pharmazie, 350, no. 5 (2017),
https://doi.org/10.1002/ardp.201600383 . .

TY  - JOUR
AU  - Dobričić, Vladimir
AU  - Francuski, Bojana M.
AU  - Jaćević, Vesna
AU  - Rodić, Marko V.
AU  - Vladimirov, Sote
AU  - Čudina, Olivera
AU  - Francuski, Đorđe
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2358
AB  - The L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid (DF) was synthesized and its crystal structure characterized by the X-ray diffraction method. The crystal system is orthorhombic with space group P2(1)2(1)2(1) and cell constants a = 8.2969(3) angstrom, b = 18.9358(8) angstrom, c = 20.0904(6) angstrom, V = 3156.4(2) angstrom(3) and Z = 4. Ring A of the steroid nucleus and phenyl ring in the 17 beta-side chain are almost planar. Rings B and C have a slightly distorted chair conformation, whereas ring D has an envelope conformation. The packing of DF is characterized by a network of intermolecular hydrogen bonds involving the O4 atom from one side of the steroid nucleus and O1 and F1 atoms from the other side as hydrogen bond acceptors. Apart from the intermolecular hydrogen bonds in the crystal packing, there are also numerous intramolecular hydrogen bonds of the N-H center dot center dot center dot O, C-H center dot center dot center dot O and C-H center dot center dot center dot F type. The local anti-inflammatory activity of DF was evaluated using the croton oil-induced ear oedema test. This derivative achieved maximal inhibition of ear oedema at significantly lower concentration in comparison with dexamethasone.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid
VL  - 80
IS  - 12
SP  - 1481
EP  - 1488
DO  - 10.2298/JSC150505067D
ER  - 

@article{
author = "Dobričić, Vladimir and Francuski, Bojana M. and Jaćević, Vesna and Rodić, Marko V. and Vladimirov, Sote and Čudina, Olivera and Francuski, Đorđe",
year = "2015",
abstract = "The L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid (DF) was synthesized and its crystal structure characterized by the X-ray diffraction method. The crystal system is orthorhombic with space group P2(1)2(1)2(1) and cell constants a = 8.2969(3) angstrom, b = 18.9358(8) angstrom, c = 20.0904(6) angstrom, V = 3156.4(2) angstrom(3) and Z = 4. Ring A of the steroid nucleus and phenyl ring in the 17 beta-side chain are almost planar. Rings B and C have a slightly distorted chair conformation, whereas ring D has an envelope conformation. The packing of DF is characterized by a network of intermolecular hydrogen bonds involving the O4 atom from one side of the steroid nucleus and O1 and F1 atoms from the other side as hydrogen bond acceptors. Apart from the intermolecular hydrogen bonds in the crystal packing, there are also numerous intramolecular hydrogen bonds of the N-H center dot center dot center dot O, C-H center dot center dot center dot O and C-H center dot center dot center dot F type. The local anti-inflammatory activity of DF was evaluated using the croton oil-induced ear oedema test. This derivative achieved maximal inhibition of ear oedema at significantly lower concentration in comparison with dexamethasone.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid",
volume = "80",
number = "12",
pages = "1481-1488",
doi = "10.2298/JSC150505067D"
}

Dobričić, V., Francuski, B. M., Jaćević, V., Rodić, M. V., Vladimirov, S., Čudina, O.,& Francuski, Đ.. (2015). Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 80(12), 1481-1488.
https://doi.org/10.2298/JSC150505067D

Dobričić V, Francuski BM, Jaćević V, Rodić MV, Vladimirov S, Čudina O, Francuski Đ. Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid. in Journal of the Serbian Chemical Society. 2015;80(12):1481-1488.
doi:10.2298/JSC150505067D .

Dobričić, Vladimir, Francuski, Bojana M., Jaćević, Vesna, Rodić, Marko V., Vladimirov, Sote, Čudina, Olivera, Francuski, Đorđe, "Synthesis, crystal structure and local anti-inflammatory activity of the L-phenylalanine methyl ester derivative of dexamethasone-derived cortienic acid" in Journal of the Serbian Chemical Society, 80, no. 12 (2015):1481-1488,
https://doi.org/10.2298/JSC150505067D . .

TY  - CONF
AU  - Milovanović, Vesna
AU  - Buha, Aleksandra
AU  - Ćurčić, Marijana
AU  - Vučinić, Slavica
AU  - Jaćević, Vesna
AU  - Janković, Saša
AU  - Antonijević, Biljana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2221
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar rats
VL  - 229
IS  - Supplement
SP  - S208
EP  - S209
DO  - 10.1016/j.toxlet.2014.06.702
ER  - 

@conference{
author = "Milovanović, Vesna and Buha, Aleksandra and Ćurčić, Marijana and Vučinić, Slavica and Jaćević, Vesna and Janković, Saša and Antonijević, Biljana",
year = "2014",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar rats",
volume = "229",
number = "Supplement",
pages = "S208-S209",
doi = "10.1016/j.toxlet.2014.06.702"
}

Milovanović, V., Buha, A., Ćurčić, M., Vučinić, S., Jaćević, V., Janković, S.,& Antonijević, B.. (2014). The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 229(Supplement), S208-S209.
https://doi.org/10.1016/j.toxlet.2014.06.702

Milovanović V, Buha A, Ćurčić M, Vučinić S, Jaćević V, Janković S, Antonijević B. The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar rats. in Toxicology Letters. 2014;229(Supplement):S208-S209.
doi:10.1016/j.toxlet.2014.06.702 .

Milovanović, Vesna, Buha, Aleksandra, Ćurčić, Marijana, Vučinić, Slavica, Jaćević, Vesna, Janković, Saša, Antonijević, Biljana, "The effects of BDE-209 on peripheral leukocyte counts in subacutely exposed Wistar rats" in Toxicology Letters, 229, no. Supplement (2014):S208-S209,
https://doi.org/10.1016/j.toxlet.2014.06.702 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Stanković, Sanja
AU  - Vučinić, Slavica
AU  - Jaćević, Vesna
AU  - Brkić, Dragica
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Antonijević, Biljana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2219
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - The effects of Cd and BDE-209 co-exposure on hematological parameters in rats
VL  - 229
IS  - Supplement
SP  - S209
EP  - S209
DO  - 10.1016/j.toxlet.2014.06.704
ER  - 

@conference{
author = "Ćurčić, Marijana and Stanković, Sanja and Vučinić, Slavica and Jaćević, Vesna and Brkić, Dragica and Đukić-Ćosić, Danijela and Antonijević, Evica and Antonijević, Biljana",
year = "2014",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The effects of Cd and BDE-209 co-exposure on hematological parameters in rats",
volume = "229",
number = "Supplement",
pages = "S209-S209",
doi = "10.1016/j.toxlet.2014.06.704"
}

Ćurčić, M., Stanković, S., Vučinić, S., Jaćević, V., Brkić, D., Đukić-Ćosić, D., Antonijević, E.,& Antonijević, B.. (2014). The effects of Cd and BDE-209 co-exposure on hematological parameters in rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 229(Supplement), S209-S209.
https://doi.org/10.1016/j.toxlet.2014.06.704

Ćurčić M, Stanković S, Vučinić S, Jaćević V, Brkić D, Đukić-Ćosić D, Antonijević E, Antonijević B. The effects of Cd and BDE-209 co-exposure on hematological parameters in rats. in Toxicology Letters. 2014;229(Supplement):S209-S209.
doi:10.1016/j.toxlet.2014.06.704 .

Ćurčić, Marijana, Stanković, Sanja, Vučinić, Slavica, Jaćević, Vesna, Brkić, Dragica, Đukić-Ćosić, Danijela, Antonijević, Evica, Antonijević, Biljana, "The effects of Cd and BDE-209 co-exposure on hematological parameters in rats" in Toxicology Letters, 229, no. Supplement (2014):S209-S209,
https://doi.org/10.1016/j.toxlet.2014.06.704 . .

TY  - JOUR
AU  - Dobričić, Vladimir
AU  - Marković, Bojan
AU  - Milenković, Nikola
AU  - Savić, Vladimir
AU  - Jaćević, Vesna
AU  - Rancić, Nemanja
AU  - Vladimirov, Sote
AU  - Čudina, Olivera
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2132
AB  - Molecular docking studies were performed on 18 17-carboxamide steroids in order to select compounds with potential local anti-inflammatory activity. These derivatives are amides of cortienic acids (obtained from hydrocortisone, prednisolone, and methylprednisolone) with methyl or ethyl esters of six amino acids. Interactions with the glucocorticoid receptor (GR), binding energies and ligand efficiency values of these compounds were compared with dexamethasone and cortienic acid obtained from prednisolone (inactive metabolite). On the basis of molecular docking studies, seven compounds were selected and their binding affinities for the GR were predicted by use of the exponential model created in this study. Subsequently, selected compounds were synthesized in good yields by use of modified N,N-dicyclohexylcarbodiimide (DCC)/1-hydroxybenzotriazole (HOBt) coupling procedure. Finally, the local anti-inflammatory activity of the synthesized compounds was examined by use of the croton oil-induced ear edema test. In vivo evaluation of systemic side effects as well as in silico prediction of metabolism were performed on the derivative with the best local anti-inflammatory activity. The combination of molecular docking studies and the exponential model for the GR binding affinity prediction could be used as an in silico tool for the rational design of novel 17-carboxamide steroids with potentially better biological profile than dexamethasone.
PB  - Wiley-VCH Verlag GMBH, Weinheim
T2  - Archiv der Pharmazie
T1  - Design, Synthesis, and Local Anti-Inflammatory Activity of 17 beta-Carboxamide Derivatives of Glucocorticoids
VL  - 347
IS  - 11
SP  - 786
EP  - 797
DO  - 10.1002/ardp.201400165
ER  - 

@article{
author = "Dobričić, Vladimir and Marković, Bojan and Milenković, Nikola and Savić, Vladimir and Jaćević, Vesna and Rancić, Nemanja and Vladimirov, Sote and Čudina, Olivera",
year = "2014",
abstract = "Molecular docking studies were performed on 18 17-carboxamide steroids in order to select compounds with potential local anti-inflammatory activity. These derivatives are amides of cortienic acids (obtained from hydrocortisone, prednisolone, and methylprednisolone) with methyl or ethyl esters of six amino acids. Interactions with the glucocorticoid receptor (GR), binding energies and ligand efficiency values of these compounds were compared with dexamethasone and cortienic acid obtained from prednisolone (inactive metabolite). On the basis of molecular docking studies, seven compounds were selected and their binding affinities for the GR were predicted by use of the exponential model created in this study. Subsequently, selected compounds were synthesized in good yields by use of modified N,N-dicyclohexylcarbodiimide (DCC)/1-hydroxybenzotriazole (HOBt) coupling procedure. Finally, the local anti-inflammatory activity of the synthesized compounds was examined by use of the croton oil-induced ear edema test. In vivo evaluation of systemic side effects as well as in silico prediction of metabolism were performed on the derivative with the best local anti-inflammatory activity. The combination of molecular docking studies and the exponential model for the GR binding affinity prediction could be used as an in silico tool for the rational design of novel 17-carboxamide steroids with potentially better biological profile than dexamethasone.",
publisher = "Wiley-VCH Verlag GMBH, Weinheim",
journal = "Archiv der Pharmazie",
title = "Design, Synthesis, and Local Anti-Inflammatory Activity of 17 beta-Carboxamide Derivatives of Glucocorticoids",
volume = "347",
number = "11",
pages = "786-797",
doi = "10.1002/ardp.201400165"
}

Dobričić, V., Marković, B., Milenković, N., Savić, V., Jaćević, V., Rancić, N., Vladimirov, S.,& Čudina, O.. (2014). Design, Synthesis, and Local Anti-Inflammatory Activity of 17 beta-Carboxamide Derivatives of Glucocorticoids. in Archiv der Pharmazie
Wiley-VCH Verlag GMBH, Weinheim., 347(11), 786-797.
https://doi.org/10.1002/ardp.201400165

Dobričić V, Marković B, Milenković N, Savić V, Jaćević V, Rancić N, Vladimirov S, Čudina O. Design, Synthesis, and Local Anti-Inflammatory Activity of 17 beta-Carboxamide Derivatives of Glucocorticoids. in Archiv der Pharmazie. 2014;347(11):786-797.
doi:10.1002/ardp.201400165 .

Dobričić, Vladimir, Marković, Bojan, Milenković, Nikola, Savić, Vladimir, Jaćević, Vesna, Rancić, Nemanja, Vladimirov, Sote, Čudina, Olivera, "Design, Synthesis, and Local Anti-Inflammatory Activity of 17 beta-Carboxamide Derivatives of Glucocorticoids" in Archiv der Pharmazie, 347, no. 11 (2014):786-797,
https://doi.org/10.1002/ardp.201400165 . .

TY  - JOUR
AU  - Buha, Aleksandra
AU  - Antonijević, Biljana
AU  - Bulat, Zorica
AU  - Jaćević, Vesna
AU  - Milovanović, Vesna
AU  - Matović, Vesna
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1981
AB  - Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and to calculate Benchmark doses for these effects. Furthermore, the effects of co-exposure to cadmium and polychlorinated biphenyls on thyroid function were investigated. Six orally-treated groups of rats were receiving 0.3, 0.6, 1.25, 2.5, 5 and 10 mg Cd/kg b.w./day, five groups were orally treated with 0.5, 1, 2, 4 and 8 mg PCBs/kgb.w./day, while nine groups of rats were orally-treated with different dose combinations of Cd and PCBs (0.6, 1.25 and 2.5 mg Cd/kgb.w. and 2,4 and 8 mg PCBs/kg b.w./day), during 28 days. Thyroid hormones were adversely affected by cadmium, with most prominent effect observed on triiodothyroxine levels indicating Cd interference with thyroid function at extrathyroidal level. Calculated Benchmark doses for Cd effects on thyroid hormones indicate triiodothyroxine as the most sensitive one that can be used as a basis for risk assessment. This study also implicates possible synergistic effects of Cd and PCBs on thyroid function as a consequence of their interference at different levels of thyroid homeostasis.
PB  - Elsevier Ireland Ltd, Clare
T2  - Toxicology Letters
T1  - The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats
VL  - 221
IS  - 2
SP  - 83
EP  - 90
DO  - 10.1016/j.toxlet.2013.06.216
ER  - 

@article{
author = "Buha, Aleksandra and Antonijević, Biljana and Bulat, Zorica and Jaćević, Vesna and Milovanović, Vesna and Matović, Vesna",
year = "2013",
abstract = "Endocrine-disrupting chemicals currently represent one of the major concerns and this study was aimed to investigate the effects of different doses of cadmium, widespread toxic metal, on the levels of thyroid hormones and to calculate Benchmark doses for these effects. Furthermore, the effects of co-exposure to cadmium and polychlorinated biphenyls on thyroid function were investigated. Six orally-treated groups of rats were receiving 0.3, 0.6, 1.25, 2.5, 5 and 10 mg Cd/kg b.w./day, five groups were orally treated with 0.5, 1, 2, 4 and 8 mg PCBs/kgb.w./day, while nine groups of rats were orally-treated with different dose combinations of Cd and PCBs (0.6, 1.25 and 2.5 mg Cd/kgb.w. and 2,4 and 8 mg PCBs/kg b.w./day), during 28 days. Thyroid hormones were adversely affected by cadmium, with most prominent effect observed on triiodothyroxine levels indicating Cd interference with thyroid function at extrathyroidal level. Calculated Benchmark doses for Cd effects on thyroid hormones indicate triiodothyroxine as the most sensitive one that can be used as a basis for risk assessment. This study also implicates possible synergistic effects of Cd and PCBs on thyroid function as a consequence of their interference at different levels of thyroid homeostasis.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats",
volume = "221",
number = "2",
pages = "83-90",
doi = "10.1016/j.toxlet.2013.06.216"
}

Buha, A., Antonijević, B., Bulat, Z., Jaćević, V., Milovanović, V.,& Matović, V.. (2013). The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 221(2), 83-90.
https://doi.org/10.1016/j.toxlet.2013.06.216

Buha A, Antonijević B, Bulat Z, Jaćević V, Milovanović V, Matović V. The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats. in Toxicology Letters. 2013;221(2):83-90.
doi:10.1016/j.toxlet.2013.06.216 .

Buha, Aleksandra, Antonijević, Biljana, Bulat, Zorica, Jaćević, Vesna, Milovanović, Vesna, Matović, Vesna, "The impact of prolonged cadmium exposure and co-exposure with polychlorinated biphenyls on thyroid function in rats" in Toxicology Letters, 221, no. 2 (2013):83-90,
https://doi.org/10.1016/j.toxlet.2013.06.216 . .

TY  - CONF
AU  - Buha, Aleksandra
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
AU  - Đukić-Ćosić, Danijela
AU  - Jaćević, Vesna
AU  - Vučinić, Slavica
AU  - Matović, Vesna
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1863
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Estimation of benchmark dose for thyroid hormone levels in rats exposed to prolonged cadmium intoxication
VL  - 221
IS  - Supplement
SP  - S222
EP  - S222
DO  - 10.1016/j.toxlet.2013.05.532
ER  - 

@conference{
author = "Buha, Aleksandra and Bulat, Zorica and Antonijević, Biljana and Đukić-Ćosić, Danijela and Jaćević, Vesna and Vučinić, Slavica and Matović, Vesna",
year = "2013",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Estimation of benchmark dose for thyroid hormone levels in rats exposed to prolonged cadmium intoxication",
volume = "221",
number = "Supplement",
pages = "S222-S222",
doi = "10.1016/j.toxlet.2013.05.532"
}

Buha, A., Bulat, Z., Antonijević, B., Đukić-Ćosić, D., Jaćević, V., Vučinić, S.,& Matović, V.. (2013). Estimation of benchmark dose for thyroid hormone levels in rats exposed to prolonged cadmium intoxication. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 221(Supplement), S222-S222.
https://doi.org/10.1016/j.toxlet.2013.05.532

Buha A, Bulat Z, Antonijević B, Đukić-Ćosić D, Jaćević V, Vučinić S, Matović V. Estimation of benchmark dose for thyroid hormone levels in rats exposed to prolonged cadmium intoxication. in Toxicology Letters. 2013;221(Supplement):S222-S222.
doi:10.1016/j.toxlet.2013.05.532 .

Buha, Aleksandra, Bulat, Zorica, Antonijević, Biljana, Đukić-Ćosić, Danijela, Jaćević, Vesna, Vučinić, Slavica, Matović, Vesna, "Estimation of benchmark dose for thyroid hormone levels in rats exposed to prolonged cadmium intoxication" in Toxicology Letters, 221, no. Supplement (2013):S222-S222,
https://doi.org/10.1016/j.toxlet.2013.05.532 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Jaćević, Vesna
AU  - Janković, Saša
AU  - Vučinić, Slavica
AU  - Durgo, Ksenija
AU  - Kopjar, Nevenka
AU  - Antonijević, Biljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1711
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Morphological and histological changes in kidneys induced by BDE209 and Cd
VL  - 211
IS  - Supplement
SP  - S158
EP  - S158
DO  - 10.1016/j.toxlet.2012.03.573
ER  - 

@conference{
author = "Ćurčić, Marijana and Jaćević, Vesna and Janković, Saša and Vučinić, Slavica and Durgo, Ksenija and Kopjar, Nevenka and Antonijević, Biljana",
year = "2012",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Morphological and histological changes in kidneys induced by BDE209 and Cd",
volume = "211",
number = "Supplement",
pages = "S158-S158",
doi = "10.1016/j.toxlet.2012.03.573"
}

Ćurčić, M., Jaćević, V., Janković, S., Vučinić, S., Durgo, K., Kopjar, N.,& Antonijević, B.. (2012). Morphological and histological changes in kidneys induced by BDE209 and Cd. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 211(Supplement), S158-S158.
https://doi.org/10.1016/j.toxlet.2012.03.573

Ćurčić M, Jaćević V, Janković S, Vučinić S, Durgo K, Kopjar N, Antonijević B. Morphological and histological changes in kidneys induced by BDE209 and Cd. in Toxicology Letters. 2012;211(Supplement):S158-S158.
doi:10.1016/j.toxlet.2012.03.573 .

Ćurčić, Marijana, Jaćević, Vesna, Janković, Saša, Vučinić, Slavica, Durgo, Ksenija, Kopjar, Nevenka, Antonijević, Biljana, "Morphological and histological changes in kidneys induced by BDE209 and Cd" in Toxicology Letters, 211, no. Supplement (2012):S158-S158,
https://doi.org/10.1016/j.toxlet.2012.03.573 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Stanković, Sanja
AU  - Janković, Saša
AU  - Vučinić, Slavica
AU  - Jaćević, Vesna
AU  - Durgo, Ksenija
AU  - Antonijević, Biljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1712
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Effects of BDE209 and Cd mixture on liver in sub-acutely exposed rats
VL  - 211
IS  - Supplement
SP  - S158
EP  - S158
DO  - 10.1016/j.toxlet.2012.03.574
ER  - 

@conference{
author = "Ćurčić, Marijana and Stanković, Sanja and Janković, Saša and Vučinić, Slavica and Jaćević, Vesna and Durgo, Ksenija and Antonijević, Biljana",
year = "2012",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Effects of BDE209 and Cd mixture on liver in sub-acutely exposed rats",
volume = "211",
number = "Supplement",
pages = "S158-S158",
doi = "10.1016/j.toxlet.2012.03.574"
}

Ćurčić, M., Stanković, S., Janković, S., Vučinić, S., Jaćević, V., Durgo, K.,& Antonijević, B.. (2012). Effects of BDE209 and Cd mixture on liver in sub-acutely exposed rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 211(Supplement), S158-S158.
https://doi.org/10.1016/j.toxlet.2012.03.574

Ćurčić M, Stanković S, Janković S, Vučinić S, Jaćević V, Durgo K, Antonijević B. Effects of BDE209 and Cd mixture on liver in sub-acutely exposed rats. in Toxicology Letters. 2012;211(Supplement):S158-S158.
doi:10.1016/j.toxlet.2012.03.574 .

Ćurčić, Marijana, Stanković, Sanja, Janković, Saša, Vučinić, Slavica, Jaćević, Vesna, Durgo, Ksenija, Antonijević, Biljana, "Effects of BDE209 and Cd mixture on liver in sub-acutely exposed rats" in Toxicology Letters, 211, no. Supplement (2012):S158-S158,
https://doi.org/10.1016/j.toxlet.2012.03.574 . .

TY  - JOUR
AU  - Ćurčić, Marijana
AU  - Janković, Saša
AU  - Jaćević, Vesna
AU  - Stanković, Sanja
AU  - Vučinić, Slavica
AU  - Durgo, Ksenija
AU  - Antonijević, Biljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1786
AB  - In relation to commonly used no-observed-adverse-effect-level (NOAEL) point of departure, because of its statistical power and reliability, Benchmark dose (BMD) approach has been proposed as an alternative in dose-response assessment. The aim of this study was to derive BMD (10%) by means of PROAST software to quantify influence of cadmium (Cd) and/or decabrominated diphenyl ether (BDE209) on thyroid hormones homestasis. Study was conducted on male Wistar rats treated orally by gavage for 28 days by either single substances or their combination. Three groups of animals were dosed with Cd at levels of 2.5, 7.5 and 15 mg/kg b.w./day, three groups of animals were dosed with BDE209 at levels of 1000, 2000 or 4000 mg/kg b.w./day, while 9 groups received different dose mixtures of previously given dose levels of Cd and BDE209 (design 3 x 3). Results of the study have indicated that Cd+BDE209 mixtures are likely more potent to disrupt thyroid function than would be expected from the chemicals individually. Derived BMD - lower confidence limits (BMDL), if ratio BMD/BMDL is  lt  10, were 9.4 mg Cd/kg b.w./day and 2155 mg BDE209/kg b.w./day for the effect on T3; and 6.22 mg Cd/kg b.w./day in the mixture with BDE209 2000 mg/kg b.w./day for the effect on FT3.
AB  - Primena statistički dobijene Benchmark doze (BMD) u proceni rizika predstavlja alternativu najčešće korišćenoj 'dozi bez štetnog efekta' (NOAEL) zbog veće pouzdanosti u analizi odnosa doze i toksičnog efekta. Cilj ovog rada bio je izračunavanje BMD (10%) primenom PROAST softvera radi kvantitativne procene uticaja Cd i/ili BDE209 na homeostazu hormona štitaste žlezde. Ispitivanje je sprovedeno na mužjacima Wistar pacova koji su putem oralne sonde, tokom 28 dana, primali pojedinačne supstance ili njihove kombinacije. Kadmijum je primenjivan u dozama od 2,5, 7,5 i 15 mg Cd/kg t.m./dan, a BDE209 u dozama od 1000, 2000 i 4000 mg BDE209/kg t.m./dan, dok je ostalih devet grupa životinja primalo kombinacije hemikalija (dizajn 3 x 3). Rezultati studije ukazuju da smeša Cd i BDE209 verovatno izaziva intenzivniji poremećaj funkcije štitaste žlezde nego svaka od supstanci pojedinačno. Izračunate Benchmark doze (10%), odnosno odgovarajuće donje granice pouzdanosti (BMDL), uz uslov da je BMD/BMDL  lt  10, iznose 9,4 mg Cd/kg t.m./dan i 2155 mg BDE209/kg t.m./dan za efekte na T3 hormon, a za efekat na FT3 hormon 6,22 mg Cd/kg t.m/dan u smeši sa BDE209 od 2000 mg/kg.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats
T1  - Primena PROAST softvera za ispitivanje uticaja dekabromovanog difeniletra i/ili kadmijuma na homeostazu hormona štitaste žlezde kod pacova
VL  - 62
IS  - 1
SP  - 1
EP  - 13
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1786
ER  - 

@article{
author = "Ćurčić, Marijana and Janković, Saša and Jaćević, Vesna and Stanković, Sanja and Vučinić, Slavica and Durgo, Ksenija and Antonijević, Biljana",
year = "2012",
abstract = "In relation to commonly used no-observed-adverse-effect-level (NOAEL) point of departure, because of its statistical power and reliability, Benchmark dose (BMD) approach has been proposed as an alternative in dose-response assessment. The aim of this study was to derive BMD (10%) by means of PROAST software to quantify influence of cadmium (Cd) and/or decabrominated diphenyl ether (BDE209) on thyroid hormones homestasis. Study was conducted on male Wistar rats treated orally by gavage for 28 days by either single substances or their combination. Three groups of animals were dosed with Cd at levels of 2.5, 7.5 and 15 mg/kg b.w./day, three groups of animals were dosed with BDE209 at levels of 1000, 2000 or 4000 mg/kg b.w./day, while 9 groups received different dose mixtures of previously given dose levels of Cd and BDE209 (design 3 x 3). Results of the study have indicated that Cd+BDE209 mixtures are likely more potent to disrupt thyroid function than would be expected from the chemicals individually. Derived BMD - lower confidence limits (BMDL), if ratio BMD/BMDL is  lt  10, were 9.4 mg Cd/kg b.w./day and 2155 mg BDE209/kg b.w./day for the effect on T3; and 6.22 mg Cd/kg b.w./day in the mixture with BDE209 2000 mg/kg b.w./day for the effect on FT3., Primena statistički dobijene Benchmark doze (BMD) u proceni rizika predstavlja alternativu najčešće korišćenoj 'dozi bez štetnog efekta' (NOAEL) zbog veće pouzdanosti u analizi odnosa doze i toksičnog efekta. Cilj ovog rada bio je izračunavanje BMD (10%) primenom PROAST softvera radi kvantitativne procene uticaja Cd i/ili BDE209 na homeostazu hormona štitaste žlezde. Ispitivanje je sprovedeno na mužjacima Wistar pacova koji su putem oralne sonde, tokom 28 dana, primali pojedinačne supstance ili njihove kombinacije. Kadmijum je primenjivan u dozama od 2,5, 7,5 i 15 mg Cd/kg t.m./dan, a BDE209 u dozama od 1000, 2000 i 4000 mg BDE209/kg t.m./dan, dok je ostalih devet grupa životinja primalo kombinacije hemikalija (dizajn 3 x 3). Rezultati studije ukazuju da smeša Cd i BDE209 verovatno izaziva intenzivniji poremećaj funkcije štitaste žlezde nego svaka od supstanci pojedinačno. Izračunate Benchmark doze (10%), odnosno odgovarajuće donje granice pouzdanosti (BMDL), uz uslov da je BMD/BMDL  lt  10, iznose 9,4 mg Cd/kg t.m./dan i 2155 mg BDE209/kg t.m./dan za efekte na T3 hormon, a za efekat na FT3 hormon 6,22 mg Cd/kg t.m/dan u smeši sa BDE209 od 2000 mg/kg.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats, Primena PROAST softvera za ispitivanje uticaja dekabromovanog difeniletra i/ili kadmijuma na homeostazu hormona štitaste žlezde kod pacova",
volume = "62",
number = "1",
pages = "1-13",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1786"
}

Ćurčić, M., Janković, S., Jaćević, V., Stanković, S., Vučinić, S., Durgo, K.,& Antonijević, B.. (2012). Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 62(1), 1-13.
https://hdl.handle.net/21.15107/rcub_farfar_1786

Ćurčić M, Janković S, Jaćević V, Stanković S, Vučinić S, Durgo K, Antonijević B. Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats. in Arhiv za farmaciju. 2012;62(1):1-13.
https://hdl.handle.net/21.15107/rcub_farfar_1786 .

Ćurčić, Marijana, Janković, Saša, Jaćević, Vesna, Stanković, Sanja, Vučinić, Slavica, Durgo, Ksenija, Antonijević, Biljana, "Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats" in Arhiv za farmaciju, 62, no. 1 (2012):1-13,
https://hdl.handle.net/21.15107/rcub_farfar_1786 .

TY  - JOUR
AU  - Ćurčić, Marijana
AU  - Janković, Saša
AU  - Jaćević, Vesna
AU  - Stanković, Sanja
AU  - Vučinić, Slavica
AU  - Durgo, Ksenija
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1627
AB  - The aim of this study was to see how a mixture of cadmium (Cd) and decabrominated diphenyl ether (BDE209) affect thyroid function, namely thyroid-stimulating hormone (TSH), thyroxin (T4), free thyroxin (FT4), triiodothyronin (T3), and free triiodothyronin (FT3) in Wistar rats (eight per group) receiving either a single substance or their combination by gavage for 28 days. Three groups were receiving Cd alone in the doses of 2.5 mg kg(-1), 7.5 mg kg(-1), or 15 mg kg(-1) b. w. a day, three groups were receiving BDE209 in the doses of 1000 mg kg(-1), 2000 mg kg(-1), or 4000 mg kg(-1) b. w. a day, while nine groups were receiving different mixtures of Cd and BDE209 in these doses (3x3 design). The results have indicated that the Cd+BDE209 mixtures more potently disrupt thyroid hormone homeostasis than would be expected from these chemicals alone.
PB  - Inst Medical Research & Occupational Health, Zagreb
T2  - Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
T1  - Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats
VL  - 63
IS  - 3
SP  - 255
EP  - 262
DO  - 10.2478/10004-1254-63-2012-2179
ER  - 

@article{
author = "Ćurčić, Marijana and Janković, Saša and Jaćević, Vesna and Stanković, Sanja and Vučinić, Slavica and Durgo, Ksenija and Bulat, Zorica and Antonijević, Biljana",
year = "2012",
abstract = "The aim of this study was to see how a mixture of cadmium (Cd) and decabrominated diphenyl ether (BDE209) affect thyroid function, namely thyroid-stimulating hormone (TSH), thyroxin (T4), free thyroxin (FT4), triiodothyronin (T3), and free triiodothyronin (FT3) in Wistar rats (eight per group) receiving either a single substance or their combination by gavage for 28 days. Three groups were receiving Cd alone in the doses of 2.5 mg kg(-1), 7.5 mg kg(-1), or 15 mg kg(-1) b. w. a day, three groups were receiving BDE209 in the doses of 1000 mg kg(-1), 2000 mg kg(-1), or 4000 mg kg(-1) b. w. a day, while nine groups were receiving different mixtures of Cd and BDE209 in these doses (3x3 design). The results have indicated that the Cd+BDE209 mixtures more potently disrupt thyroid hormone homeostasis than would be expected from these chemicals alone.",
publisher = "Inst Medical Research & Occupational Health, Zagreb",
journal = "Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology",
title = "Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats",
volume = "63",
number = "3",
pages = "255-262",
doi = "10.2478/10004-1254-63-2012-2179"
}

Ćurčić, M., Janković, S., Jaćević, V., Stanković, S., Vučinić, S., Durgo, K., Bulat, Z.,& Antonijević, B.. (2012). Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats. in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
Inst Medical Research & Occupational Health, Zagreb., 63(3), 255-262.
https://doi.org/10.2478/10004-1254-63-2012-2179

Ćurčić M, Janković S, Jaćević V, Stanković S, Vučinić S, Durgo K, Bulat Z, Antonijević B. Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats. in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology. 2012;63(3):255-262.
doi:10.2478/10004-1254-63-2012-2179 .

Ćurčić, Marijana, Janković, Saša, Jaćević, Vesna, Stanković, Sanja, Vučinić, Slavica, Durgo, Ksenija, Bulat, Zorica, Antonijević, Biljana, "Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats" in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology, 63, no. 3 (2012):255-262,
https://doi.org/10.2478/10004-1254-63-2012-2179 . .

TY  - JOUR
AU  - Antonijević, Biljana
AU  - Milovanović, Vesna
AU  - Ćurčić, Marijana
AU  - Janković, Saša
AU  - Jaćević, Vesna
AU  - Vučinić, Slavica
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1835
AB  - Polychlorinated biphenyls (PCBs) and brominated flame retardants, polybrominated diphenylethers (PBDEs), are widespread environmental contaminants as a result of anthropogenic activities and due to their persistency and resistance to degradation. Both groups of chemicals are placed on the list of persistent organic pollutants (POPs), covered by the Stockholm convention which is aimed to limit or ban the production, use, emission, import and export of POPs in order to protect human health and the environment. Taking into account the structural similarity between PCBs and PBDEs, and the known effects of PCBs, these two groups of chemicals could have similar mechanisms of action. Also, because of real simultaneous exposure to these compounds, an examination of possible interactions is of great importance. Interactions of the compounds from these groups are likely at the system level of hormones, particularly thyroid and reproductive ones. As there are mechanisms of adverse effects of both groups of chemicals on the nervous system, including functional, neurological and behavioral changes, there are influences on neurotransmiters, changes in signal transduction and apoptosis. There are interactions affecting the occurrence of metabolic disorders as well. Data on the toxicity of mixtures of PCBs and PBDEs, as well as interactions of these chemicals would contribute to the processes of risk evaluation and risk characterisation.
AB  - Polihlorovani bifenili (PCBs) i bromovani usporivači gorenja, polibromovani difenil etri (PBDEs) su široko rasprostranjeni u životnoj sredini kao posledica antropogenih aktivnosti i zahvaljujući njihovoj postojanosti i otpornosti na degradaciju. Obe grupe jedinjenja se nalaze na listi perzistentnih organskih zagađivača (POPs) usvojenoj Stokholmskom konvencijom sa ciljem da zabrani ili ograniči proizvodnju, upotrebu, emisiju ili uvoz i izvoz toksičnih supstanci označenih kao POPs u svrhu zaštite zdravlja ljudi i životne sredine. Uzimajući u obzir strukturnu sličnost između PBDEs i PCBs, kao i činjenicu da je istovremena ekspozicija ovim jedinjenima realna, ispitivanja njihovih interakcija su od značaja za predviđanje rezultujućeg efekta. Saznanja u oblasti toksikologije smeša, takođe doprinose procesu evaluacije i karakterizacije rizika. Interakcije jedinjenja iz ovih grupa su verovatne na nivou endokrinog sistema, naročito tiroidnog i reproduktivnog. S obzirom na mehanizme toksičnosti obe grupe supstanci za nervni sistem, uključujući funkcionalne promene, neurološke poremećaje i promene u ponašanju, moguće je očekivati njihove interakcije i na sistemima neurotransmitera, promene u prenosu signala i izazivanje apoptoze, kao i na pojavu metaboličkih poremećaja.
PB  - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
T2  - Veterinarski glasnik
T1  - Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers
T1  - Mehanizmi toksičnog dejstva i interakcije polihlorovanih bifenila i polibromovanih difenil etara
VL  - 66
IS  - 3-4
SP  - 259
EP  - 271
DO  - 10.2298/VETGL1204259A
ER  - 

@article{
author = "Antonijević, Biljana and Milovanović, Vesna and Ćurčić, Marijana and Janković, Saša and Jaćević, Vesna and Vučinić, Slavica",
year = "2012",
abstract = "Polychlorinated biphenyls (PCBs) and brominated flame retardants, polybrominated diphenylethers (PBDEs), are widespread environmental contaminants as a result of anthropogenic activities and due to their persistency and resistance to degradation. Both groups of chemicals are placed on the list of persistent organic pollutants (POPs), covered by the Stockholm convention which is aimed to limit or ban the production, use, emission, import and export of POPs in order to protect human health and the environment. Taking into account the structural similarity between PCBs and PBDEs, and the known effects of PCBs, these two groups of chemicals could have similar mechanisms of action. Also, because of real simultaneous exposure to these compounds, an examination of possible interactions is of great importance. Interactions of the compounds from these groups are likely at the system level of hormones, particularly thyroid and reproductive ones. As there are mechanisms of adverse effects of both groups of chemicals on the nervous system, including functional, neurological and behavioral changes, there are influences on neurotransmiters, changes in signal transduction and apoptosis. There are interactions affecting the occurrence of metabolic disorders as well. Data on the toxicity of mixtures of PCBs and PBDEs, as well as interactions of these chemicals would contribute to the processes of risk evaluation and risk characterisation., Polihlorovani bifenili (PCBs) i bromovani usporivači gorenja, polibromovani difenil etri (PBDEs) su široko rasprostranjeni u životnoj sredini kao posledica antropogenih aktivnosti i zahvaljujući njihovoj postojanosti i otpornosti na degradaciju. Obe grupe jedinjenja se nalaze na listi perzistentnih organskih zagađivača (POPs) usvojenoj Stokholmskom konvencijom sa ciljem da zabrani ili ograniči proizvodnju, upotrebu, emisiju ili uvoz i izvoz toksičnih supstanci označenih kao POPs u svrhu zaštite zdravlja ljudi i životne sredine. Uzimajući u obzir strukturnu sličnost između PBDEs i PCBs, kao i činjenicu da je istovremena ekspozicija ovim jedinjenima realna, ispitivanja njihovih interakcija su od značaja za predviđanje rezultujućeg efekta. Saznanja u oblasti toksikologije smeša, takođe doprinose procesu evaluacije i karakterizacije rizika. Interakcije jedinjenja iz ovih grupa su verovatne na nivou endokrinog sistema, naročito tiroidnog i reproduktivnog. S obzirom na mehanizme toksičnosti obe grupe supstanci za nervni sistem, uključujući funkcionalne promene, neurološke poremećaje i promene u ponašanju, moguće je očekivati njihove interakcije i na sistemima neurotransmitera, promene u prenosu signala i izazivanje apoptoze, kao i na pojavu metaboličkih poremećaja.",
publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd",
journal = "Veterinarski glasnik",
title = "Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers, Mehanizmi toksičnog dejstva i interakcije polihlorovanih bifenila i polibromovanih difenil etara",
volume = "66",
number = "3-4",
pages = "259-271",
doi = "10.2298/VETGL1204259A"
}

Antonijević, B., Milovanović, V., Ćurčić, M., Janković, S., Jaćević, V.,& Vučinić, S.. (2012). Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers. in Veterinarski glasnik
Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(3-4), 259-271.
https://doi.org/10.2298/VETGL1204259A

Antonijević B, Milovanović V, Ćurčić M, Janković S, Jaćević V, Vučinić S. Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers. in Veterinarski glasnik. 2012;66(3-4):259-271.
doi:10.2298/VETGL1204259A .

Antonijević, Biljana, Milovanović, Vesna, Ćurčić, Marijana, Janković, Saša, Jaćević, Vesna, Vučinić, Slavica, "Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers" in Veterinarski glasnik, 66, no. 3-4 (2012):259-271,
https://doi.org/10.2298/VETGL1204259A . .

TY  - JOUR
AU  - Kukić-Marković, Jelena
AU  - Dobrić, Silva
AU  - Jaćević, Vesna
AU  - Topić, Aleksandra
AU  - Petrović, Silvana
AU  - Marin, Petar
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1494
AB  - The influence of methanol extracts of four Stachys species from Balkan on carbon tetrachloride induced hepatotoxicity in rats was investigated. The extracts were obtained from aerial parts of S. beckeana Dorfler & Hayek, S. anisochila Vis. et Pancic, S. plumosa Griseb. and S. alpina L. subsp. dinarica Murb. The liver damage was induced by s.c. injections of carbon tetrachloride (2.5 ml/kg b.w.) and the extracts were then consecutively applied for five days. Their effects were evaluated through alteration of biochemical parameters (liver enzymes in the serum), as well as through histopathological changes in the liver (liver damage score, LDS). Treatment of CCl(4)-intoxicated rats with methanol extracts of investigated Stachys taxa (200 and 100 mg/kg b.w. p.o.) significantly reduced increased level of marker enzymes aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) in the serum (with the exception of AST and ALT after 100 mg/kg of S. anisochila extract was administered). Vast degenerative and vascular changes in CCl(4)-treated rats were also notably reduced after the treatment with investigated extracts, corroborating the biochemical observations and confirming their hepatoprotective effects. The best dose-dependant activity was achieved by the methanol extract of S. alpina subsp. dinarica.
PB  - Inst Materials Physics, Bucharest
T2  - Digest Journal of Nanomaterials and Biostructures
T1  - Influence of selected stachys extracts on carbon tetrachloride-induced liver damage in rats
VL  - 6
IS  - 3
SP  - 1035
EP  - 1041
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1494
ER  - 

@article{
author = "Kukić-Marković, Jelena and Dobrić, Silva and Jaćević, Vesna and Topić, Aleksandra and Petrović, Silvana and Marin, Petar",
year = "2011",
abstract = "The influence of methanol extracts of four Stachys species from Balkan on carbon tetrachloride induced hepatotoxicity in rats was investigated. The extracts were obtained from aerial parts of S. beckeana Dorfler & Hayek, S. anisochila Vis. et Pancic, S. plumosa Griseb. and S. alpina L. subsp. dinarica Murb. The liver damage was induced by s.c. injections of carbon tetrachloride (2.5 ml/kg b.w.) and the extracts were then consecutively applied for five days. Their effects were evaluated through alteration of biochemical parameters (liver enzymes in the serum), as well as through histopathological changes in the liver (liver damage score, LDS). Treatment of CCl(4)-intoxicated rats with methanol extracts of investigated Stachys taxa (200 and 100 mg/kg b.w. p.o.) significantly reduced increased level of marker enzymes aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) in the serum (with the exception of AST and ALT after 100 mg/kg of S. anisochila extract was administered). Vast degenerative and vascular changes in CCl(4)-treated rats were also notably reduced after the treatment with investigated extracts, corroborating the biochemical observations and confirming their hepatoprotective effects. The best dose-dependant activity was achieved by the methanol extract of S. alpina subsp. dinarica.",
publisher = "Inst Materials Physics, Bucharest",
journal = "Digest Journal of Nanomaterials and Biostructures",
title = "Influence of selected stachys extracts on carbon tetrachloride-induced liver damage in rats",
volume = "6",
number = "3",
pages = "1035-1041",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1494"
}

Kukić-Marković, J., Dobrić, S., Jaćević, V., Topić, A., Petrović, S.,& Marin, P.. (2011). Influence of selected stachys extracts on carbon tetrachloride-induced liver damage in rats. in Digest Journal of Nanomaterials and Biostructures
Inst Materials Physics, Bucharest., 6(3), 1035-1041.
https://hdl.handle.net/21.15107/rcub_farfar_1494

Kukić-Marković J, Dobrić S, Jaćević V, Topić A, Petrović S, Marin P. Influence of selected stachys extracts on carbon tetrachloride-induced liver damage in rats. in Digest Journal of Nanomaterials and Biostructures. 2011;6(3):1035-1041.
https://hdl.handle.net/21.15107/rcub_farfar_1494 .

Kukić-Marković, Jelena, Dobrić, Silva, Jaćević, Vesna, Topić, Aleksandra, Petrović, Silvana, Marin, Petar, "Influence of selected stachys extracts on carbon tetrachloride-induced liver damage in rats" in Digest Journal of Nanomaterials and Biostructures, 6, no. 3 (2011):1035-1041,
https://hdl.handle.net/21.15107/rcub_farfar_1494 .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Stanković, Sanja
AU  - Jaćević, Vesna
AU  - Janković, Saša
AU  - Durgo, Ksenija
AU  - Milovanović, Vesna
AU  - Vučinić, Slavica
AU  - Antonijević, Biljana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1473
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Serum liver enzyme levels in Wistar rats 28 days orally exposed to the mixture of BDE209 and cadmium
VL  - 205
IS  - Supplement
SP  - S210
EP  - S211
DO  - 10.1016/j.toxlet.2011.05.724
ER  - 

@conference{
author = "Ćurčić, Marijana and Stanković, Sanja and Jaćević, Vesna and Janković, Saša and Durgo, Ksenija and Milovanović, Vesna and Vučinić, Slavica and Antonijević, Biljana",
year = "2011",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Serum liver enzyme levels in Wistar rats 28 days orally exposed to the mixture of BDE209 and cadmium",
volume = "205",
number = "Supplement",
pages = "S210-S211",
doi = "10.1016/j.toxlet.2011.05.724"
}

Ćurčić, M., Stanković, S., Jaćević, V., Janković, S., Durgo, K., Milovanović, V., Vučinić, S.,& Antonijević, B.. (2011). Serum liver enzyme levels in Wistar rats 28 days orally exposed to the mixture of BDE209 and cadmium. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 205(Supplement), S210-S211.
https://doi.org/10.1016/j.toxlet.2011.05.724

Ćurčić M, Stanković S, Jaćević V, Janković S, Durgo K, Milovanović V, Vučinić S, Antonijević B. Serum liver enzyme levels in Wistar rats 28 days orally exposed to the mixture of BDE209 and cadmium. in Toxicology Letters. 2011;205(Supplement):S210-S211.
doi:10.1016/j.toxlet.2011.05.724 .

Ćurčić, Marijana, Stanković, Sanja, Jaćević, Vesna, Janković, Saša, Durgo, Ksenija, Milovanović, Vesna, Vučinić, Slavica, Antonijević, Biljana, "Serum liver enzyme levels in Wistar rats 28 days orally exposed to the mixture of BDE209 and cadmium" in Toxicology Letters, 205, no. Supplement (2011):S210-S211,
https://doi.org/10.1016/j.toxlet.2011.05.724 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Jaćević, Vesna
AU  - Stanković, Sanja
AU  - Janković, Saša
AU  - Durgo, Ksenija
AU  - Vučinić, Slavica
AU  - Antonijević, Biljana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1474
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Effects of BDE 209 and cadmium mixture on thyroid hormone levels in rats
VL  - 205
IS  - Supplement
SP  - S211
EP  - S211
DO  - 10.1016/j.toxlet.2011.05.725
ER  - 

@conference{
author = "Ćurčić, Marijana and Jaćević, Vesna and Stanković, Sanja and Janković, Saša and Durgo, Ksenija and Vučinić, Slavica and Antonijević, Biljana",
year = "2011",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Effects of BDE 209 and cadmium mixture on thyroid hormone levels in rats",
volume = "205",
number = "Supplement",
pages = "S211-S211",
doi = "10.1016/j.toxlet.2011.05.725"
}

Ćurčić, M., Jaćević, V., Stanković, S., Janković, S., Durgo, K., Vučinić, S.,& Antonijević, B.. (2011). Effects of BDE 209 and cadmium mixture on thyroid hormone levels in rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 205(Supplement), S211-S211.
https://doi.org/10.1016/j.toxlet.2011.05.725

Ćurčić M, Jaćević V, Stanković S, Janković S, Durgo K, Vučinić S, Antonijević B. Effects of BDE 209 and cadmium mixture on thyroid hormone levels in rats. in Toxicology Letters. 2011;205(Supplement):S211-S211.
doi:10.1016/j.toxlet.2011.05.725 .

Ćurčić, Marijana, Jaćević, Vesna, Stanković, Sanja, Janković, Saša, Durgo, Ksenija, Vučinić, Slavica, Antonijević, Biljana, "Effects of BDE 209 and cadmium mixture on thyroid hormone levels in rats" in Toxicology Letters, 205, no. Supplement (2011):S211-S211,
https://doi.org/10.1016/j.toxlet.2011.05.725 . .

TY  - JOUR
AU  - Ćurčić, Marijana
AU  - Antonijević, Biljana
AU  - Durgo, Ksenija
AU  - Janković, Saša
AU  - Jaćević, Vesna
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1442
AB  - Polybrominated diphenyl ethers (PBDEs) represent group of persistant organic chemicals (POPs), usually used as flame retardant additives in a variety of matherials and commercial products. Since 2009, PBDEs have been placed on the list of POPs chemicals, covered by Stockholm convention which is aimed to limit or ban production, use, emission, import and export of persistent organic pollutants, due to human health and environmental protection. Predominant routes of human exposure by PBDEs are ingestion by food, inhalation or dermal. Based on experimental studies, targets for PBDEs toxicity are nervous system, liver, thyroid gland and development. According to International Agency for Research on Cancer (IARC) PBDEs are not classified as a carcinogens, whereas according to Environmental Protection Agency (EPA) only deca BDE is classified as possible human carcinogen. So far, PBDEs have not been incoporated in national legislative framework. There are no data on environmental contamination, occupational exposure and exposure of general population. Therefore, placing the data on PBDEs in the focus of publics could contribute to the process of risk characterisation, and give directions for risk management in the Republic of Serbia.
AB  - Polibromovani difeniletri (PBDEs) su hemikalije koje se dodaju različitim proizvodima kojima smo okruženi u svakodnevnom životu da bi usporili i/ili sprečili izbijanja požara. Polibromovani difeniletri su 2009. godine pridruženi listi perzistentnih organskih polutanata (POPs) usvojenoj Stokholmskom konvencijom čiji je cilj da ograniči ili zabrani proizvodnju, upotrebu, emisiju ili uvoz i izvoz toksičnih supstanci označenih kao POPs radi zaštite zdravlja ljudi i životne sredine. Do ekspozicije ljudi PBDEs može doći ingestijom, inhalacijom, dermalno. Eksperimentalne studije ukazuju da PBDEs najznačajnije toksične efekte ispoljavaju na jetru, štitnu žlezdu, nervni sistem, rast i razvoj. Međunarodna agencija za istraživanje karcinoma (IARC) ne klasifikuje PBDEs kao karcinogene za ljude, a Američka agencija za zaštitu životne sredine (EPA) klasifikuje samo dekaBDE kao moguć karcinogen za ljude. U našoj zemlji PBDEs nisu inkorporirani u nacionalnu regulativu, nema podataka o nivou zagađenja životne sredine, o sadržaju ovih jedinjenja u radnom okruženju i ekpoziciji opšte populacije, stoga bi saznanja u ovoj oblasti doprinela procesu evaluacije i karakterizacije rizika, ali i dala smernice za upravljanje rizikom PBDEs hemikalijama u Republici Srbiji.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Toxicological relevance and potential risk due to polybrominated diphenylethers exposure
T1  - Toksikološki značaj i potencijalni rizik pri ekspoziciji polibromovanim difeniletrima
VL  - 60
IS  - 3
SP  - 311
EP  - 322
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1442
ER  - 

@article{
author = "Ćurčić, Marijana and Antonijević, Biljana and Durgo, Ksenija and Janković, Saša and Jaćević, Vesna",
year = "2010",
abstract = "Polybrominated diphenyl ethers (PBDEs) represent group of persistant organic chemicals (POPs), usually used as flame retardant additives in a variety of matherials and commercial products. Since 2009, PBDEs have been placed on the list of POPs chemicals, covered by Stockholm convention which is aimed to limit or ban production, use, emission, import and export of persistent organic pollutants, due to human health and environmental protection. Predominant routes of human exposure by PBDEs are ingestion by food, inhalation or dermal. Based on experimental studies, targets for PBDEs toxicity are nervous system, liver, thyroid gland and development. According to International Agency for Research on Cancer (IARC) PBDEs are not classified as a carcinogens, whereas according to Environmental Protection Agency (EPA) only deca BDE is classified as possible human carcinogen. So far, PBDEs have not been incoporated in national legislative framework. There are no data on environmental contamination, occupational exposure and exposure of general population. Therefore, placing the data on PBDEs in the focus of publics could contribute to the process of risk characterisation, and give directions for risk management in the Republic of Serbia., Polibromovani difeniletri (PBDEs) su hemikalije koje se dodaju različitim proizvodima kojima smo okruženi u svakodnevnom životu da bi usporili i/ili sprečili izbijanja požara. Polibromovani difeniletri su 2009. godine pridruženi listi perzistentnih organskih polutanata (POPs) usvojenoj Stokholmskom konvencijom čiji je cilj da ograniči ili zabrani proizvodnju, upotrebu, emisiju ili uvoz i izvoz toksičnih supstanci označenih kao POPs radi zaštite zdravlja ljudi i životne sredine. Do ekspozicije ljudi PBDEs može doći ingestijom, inhalacijom, dermalno. Eksperimentalne studije ukazuju da PBDEs najznačajnije toksične efekte ispoljavaju na jetru, štitnu žlezdu, nervni sistem, rast i razvoj. Međunarodna agencija za istraživanje karcinoma (IARC) ne klasifikuje PBDEs kao karcinogene za ljude, a Američka agencija za zaštitu životne sredine (EPA) klasifikuje samo dekaBDE kao moguć karcinogen za ljude. U našoj zemlji PBDEs nisu inkorporirani u nacionalnu regulativu, nema podataka o nivou zagađenja životne sredine, o sadržaju ovih jedinjenja u radnom okruženju i ekpoziciji opšte populacije, stoga bi saznanja u ovoj oblasti doprinela procesu evaluacije i karakterizacije rizika, ali i dala smernice za upravljanje rizikom PBDEs hemikalijama u Republici Srbiji.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Toxicological relevance and potential risk due to polybrominated diphenylethers exposure, Toksikološki značaj i potencijalni rizik pri ekspoziciji polibromovanim difeniletrima",
volume = "60",
number = "3",
pages = "311-322",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1442"
}

Ćurčić, M., Antonijević, B., Durgo, K., Janković, S.,& Jaćević, V.. (2010). Toxicological relevance and potential risk due to polybrominated diphenylethers exposure. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 60(3), 311-322.
https://hdl.handle.net/21.15107/rcub_farfar_1442

Ćurčić M, Antonijević B, Durgo K, Janković S, Jaćević V. Toxicological relevance and potential risk due to polybrominated diphenylethers exposure. in Arhiv za farmaciju. 2010;60(3):311-322.
https://hdl.handle.net/21.15107/rcub_farfar_1442 .

Ćurčić, Marijana, Antonijević, Biljana, Durgo, Ksenija, Janković, Saša, Jaćević, Vesna, "Toxicological relevance and potential risk due to polybrominated diphenylethers exposure" in Arhiv za farmaciju, 60, no. 3 (2010):311-322,
https://hdl.handle.net/21.15107/rcub_farfar_1442 .

TY  - CONF
AU  - Kukić-Marković, Jelena
AU  - Dobrić, Silva
AU  - Jaćević, Vesna
AU  - Topić, Aleksandra
AU  - Marin, Petar
AU  - Petrović, Silvana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1285
PB  - Georg Thieme Verlag Kg, Stuttgart
C3  - Planta Medica
T1  - Hepatoprotective activity of Stachys extracts against CCl4-induced hepatotoxicity in rats
VL  - 75
IS  - 9
SP  - 1039
EP  - 1039
DO  - 10.1055/s-0029-1234842
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1285
ER  - 

@conference{
author = "Kukić-Marković, Jelena and Dobrić, Silva and Jaćević, Vesna and Topić, Aleksandra and Marin, Petar and Petrović, Silvana",
year = "2009",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "Planta Medica",
title = "Hepatoprotective activity of Stachys extracts against CCl4-induced hepatotoxicity in rats",
volume = "75",
number = "9",
pages = "1039-1039",
doi = "10.1055/s-0029-1234842",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1285"
}

Kukić-Marković, J., Dobrić, S., Jaćević, V., Topić, A., Marin, P.,& Petrović, S.. (2009). Hepatoprotective activity of Stachys extracts against CCl4-induced hepatotoxicity in rats. in Planta Medica
Georg Thieme Verlag Kg, Stuttgart., 75(9), 1039-1039.
https://doi.org/10.1055/s-0029-1234842
https://hdl.handle.net/21.15107/rcub_farfar_1285

Kukić-Marković J, Dobrić S, Jaćević V, Topić A, Marin P, Petrović S. Hepatoprotective activity of Stachys extracts against CCl4-induced hepatotoxicity in rats. in Planta Medica. 2009;75(9):1039-1039.
doi:10.1055/s-0029-1234842
https://hdl.handle.net/21.15107/rcub_farfar_1285 .

Kukić-Marković, Jelena, Dobrić, Silva, Jaćević, Vesna, Topić, Aleksandra, Marin, Petar, Petrović, Silvana, "Hepatoprotective activity of Stachys extracts against CCl4-induced hepatotoxicity in rats" in Planta Medica, 75, no. 9 (2009):1039-1039,
https://doi.org/10.1055/s-0029-1234842 .,
https://hdl.handle.net/21.15107/rcub_farfar_1285 .

TY  - CONF
AU  - Marković, Bojan
AU  - Vladimirov, S.
AU  - Pitić, D.
AU  - Savić, Vladimir
AU  - Jaćević, Vesna
AU  - Dobrić, Silva
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1196
AB  - In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.
PB  - Medimond S R L, 40128 Bologna
C3  - Joint Meeting on Medical Chemistry
T1  - Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide
SP  - 41
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1196
ER  - 

@conference{
author = "Marković, Bojan and Vladimirov, S. and Pitić, D. and Savić, Vladimir and Jaćević, Vesna and Dobrić, Silva",
year = "2009",
abstract = "In this study it was described synthesis of new C-21 esters of fluocinolone acetonide with alpha-alkoxyalcanoic and alpha-aryloxyalkanoic acids. Esterification with these branched oxyacids has to improve benefit-risk ratio. All synthesized compound were shown some topical anti-inflammatory activity.",
publisher = "Medimond S R L, 40128 Bologna",
journal = "Joint Meeting on Medical Chemistry",
title = "Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide",
pages = "41",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1196"
}

Marković, B., Vladimirov, S., Pitić, D., Savić, V., Jaćević, V.,& Dobrić, S.. (2009). Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide. in Joint Meeting on Medical Chemistry
Medimond S R L, 40128 Bologna., 41.
https://hdl.handle.net/21.15107/rcub_farfar_1196

Marković B, Vladimirov S, Pitić D, Savić V, Jaćević V, Dobrić S. Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide. in Joint Meeting on Medical Chemistry. 2009;:41.
https://hdl.handle.net/21.15107/rcub_farfar_1196 .

Marković, Bojan, Vladimirov, S., Pitić, D., Savić, Vladimir, Jaćević, Vesna, Dobrić, Silva, "Synthesis and Anti-inflammatory Activity of New alpha-Oxyalcanoyl Esters of Fluocinolone Acetonide" in Joint Meeting on Medical Chemistry (2009):41,
https://hdl.handle.net/21.15107/rcub_farfar_1196 .