TY  - CONF
AU  - Antonijević-Miljaković, Evica
AU  - Andrys, Rudolf
AU  - Antonijević, Biljana
AU  - Musilek, Kamil
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5435
AB  - Imobilizacija enzima predstavlja značajnu naučnu metodologiju zbog odličnog funkcionalnog poboljšanja
svojstava proteina kao što su ponovna upotreba, ekonomičnost i lako odvajanje od reakcionog medijuma. ..
AB  - Enzyme immobilization presents substantial scientific methodology due to excellent functional improvement
of protein properties such as reusability, cost-effectiveness and easy separation from the reaction medium. ...
PB  - Udruženje toksikologa Srbije
C3  - 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference, 10-12 May, 2023, Belgrade, Abstract Book
T1  - Imobilizacija enzima kao strategija za efikasno i održivo određivanje inhibitora i reaktivatora holinesteraza
T1  - Enzyme immobilization as a strategy towards efficient and sustainable determination of cholinesterase inhibitors and reactivators
SP  - 78
EP  - 79
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5435
ER  - 

@conference{
author = "Antonijević-Miljaković, Evica and Andrys, Rudolf and Antonijević, Biljana and Musilek, Kamil",
year = "2023",
abstract = "Imobilizacija enzima predstavlja značajnu naučnu metodologiju zbog odličnog funkcionalnog poboljšanja
svojstava proteina kao što su ponovna upotreba, ekonomičnost i lako odvajanje od reakcionog medijuma. .., Enzyme immobilization presents substantial scientific methodology due to excellent functional improvement
of protein properties such as reusability, cost-effectiveness and easy separation from the reaction medium. ...",
publisher = "Udruženje toksikologa Srbije",
journal = "13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference, 10-12 May, 2023, Belgrade, Abstract Book",
title = "Imobilizacija enzima kao strategija za efikasno i održivo određivanje inhibitora i reaktivatora holinesteraza, Enzyme immobilization as a strategy towards efficient and sustainable determination of cholinesterase inhibitors and reactivators",
pages = "78-79",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5435"
}

Antonijević-Miljaković, E., Andrys, R., Antonijević, B.,& Musilek, K.. (2023). Imobilizacija enzima kao strategija za efikasno i održivo određivanje inhibitora i reaktivatora holinesteraza. in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference, 10-12 May, 2023, Belgrade, Abstract Book
Udruženje toksikologa Srbije., 78-79.
https://hdl.handle.net/21.15107/rcub_farfar_5435

Antonijević-Miljaković E, Andrys R, Antonijević B, Musilek K. Imobilizacija enzima kao strategija za efikasno i održivo određivanje inhibitora i reaktivatora holinesteraza. in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference, 10-12 May, 2023, Belgrade, Abstract Book. 2023;:78-79.
https://hdl.handle.net/21.15107/rcub_farfar_5435 .

Antonijević-Miljaković, Evica, Andrys, Rudolf, Antonijević, Biljana, Musilek, Kamil, "Imobilizacija enzima kao strategija za efikasno i održivo određivanje inhibitora i reaktivatora holinesteraza" in 13th international congress of the Serbian society of toxicology & 1st toxSEE regional conference, 10-12 May, 2023, Belgrade, Abstract Book (2023):78-79,
https://hdl.handle.net/21.15107/rcub_farfar_5435 .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Musilek, Kamil
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Anđelković, Milena
AU  - Buha-Đorđević, Aleksandra
AU  - Antonijević, Biljana
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3249
PB  - Elsevier Ireland Ltd, Clare
T2  - Chemico-Biological Interactions
T1  - Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation
VL  - 308
SP  - 385
EP  - 391
DO  - 10.1016/j.cbi.2019.05.034
ER  - 

@article{
author = "Antonijević, Evica and Musilek, Kamil and Kuca, Kamil and Đukić-Ćosić, Danijela and Anđelković, Milena and Buha-Đorđević, Aleksandra and Antonijević, Biljana",
year = "2019",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Chemico-Biological Interactions",
title = "Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation",
volume = "308",
pages = "385-391",
doi = "10.1016/j.cbi.2019.05.034"
}

Antonijević, E., Musilek, K., Kuca, K., Đukić-Ćosić, D., Anđelković, M., Buha-Đorđević, A.,& Antonijević, B.. (2019). Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation. in Chemico-Biological Interactions
Elsevier Ireland Ltd, Clare., 308, 385-391.
https://doi.org/10.1016/j.cbi.2019.05.034

Antonijević E, Musilek K, Kuca K, Đukić-Ćosić D, Anđelković M, Buha-Đorđević A, Antonijević B. Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation. in Chemico-Biological Interactions. 2019;308:385-391.
doi:10.1016/j.cbi.2019.05.034 .

Antonijević, Evica, Musilek, Kamil, Kuca, Kamil, Đukić-Ćosić, Danijela, Anđelković, Milena, Buha-Đorđević, Aleksandra, Antonijević, Biljana, "Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation" in Chemico-Biological Interactions, 308 (2019):385-391,
https://doi.org/10.1016/j.cbi.2019.05.034 . .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Kotur-Stevuljević, Jelena
AU  - Musilek, Kamil
AU  - Kosvancova, Andrea
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Spasojević-Kalimanovska, Vesna
AU  - Antonijević, Biljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3170
AB  - Beside the key inhibition of acetylcholinesterase (AChE), involvement of oxidative stress in organophosphate (OP)-induced toxicity has been supported by experimental and human studies. On the other hand, according to our best knowledge, possible antioxidant properties of oximes, the only causal antidotes to OP-inhibited AChE, have been examined only by a few studies. Thus, we have determined the effect of four conventional (obidoxime, trimedoxime, pralidoxime, asoxime) and two promising experimental oximes (K027, K203) on dichlorvos (DDVP)-induced oxidative changes in vivo. Wistar rats (5/group) were treated with oxime (5% LD50 i.m) immediately after DDVP challenge (75% LD50 s.c). Oxidative stress biomarkers were determined in plasma and brain 60 min after the treatment: prooxidative-superoxide anion (O-2 (center dot-)) and total oxidative status (TOS); antioxidative-superoxide dismutase (SOD), total thiol (SH) groups, total antioxidant status (TAS) and paraoxonase (PON1); tissue oxidative stress burden-prooxidative-antioxidative balance (PAB) and oxidative stress index (OSI); oxidative tissue damage-malondialdehyde (MDA) and advanced oxidation protein products (AOPP). All oximes were able to attenuate DDVP-induced oxidative stress in rat plasma and brain. Changes of determined parameters in brain were not as prominent as it was seen in plasma. Based on OSI, better abilities of oxime K027, K203 and obidoxime to maintain DDVP-induced oxidative stress in rat brain were shown as compared to trimedoxime, pralidoxime and asoxime. Oximes can influence the complex in vivo redox processes that might contribute to their overall therapeutic efficacy. Further research is needed to understand the underlying molecular mechanisms involved in this phenomenon.
PB  - Springer Heidelberg, Heidelberg
T2  - Archives of Toxicology
T1  - Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain
VL  - 92
IS  - 2
SP  - 745
EP  - 757
DO  - 10.1007/s00204-017-2101-z
ER  - 

@article{
author = "Antonijević, Evica and Kotur-Stevuljević, Jelena and Musilek, Kamil and Kosvancova, Andrea and Kuca, Kamil and Đukić-Ćosić, Danijela and Spasojević-Kalimanovska, Vesna and Antonijević, Biljana",
year = "2018",
abstract = "Beside the key inhibition of acetylcholinesterase (AChE), involvement of oxidative stress in organophosphate (OP)-induced toxicity has been supported by experimental and human studies. On the other hand, according to our best knowledge, possible antioxidant properties of oximes, the only causal antidotes to OP-inhibited AChE, have been examined only by a few studies. Thus, we have determined the effect of four conventional (obidoxime, trimedoxime, pralidoxime, asoxime) and two promising experimental oximes (K027, K203) on dichlorvos (DDVP)-induced oxidative changes in vivo. Wistar rats (5/group) were treated with oxime (5% LD50 i.m) immediately after DDVP challenge (75% LD50 s.c). Oxidative stress biomarkers were determined in plasma and brain 60 min after the treatment: prooxidative-superoxide anion (O-2 (center dot-)) and total oxidative status (TOS); antioxidative-superoxide dismutase (SOD), total thiol (SH) groups, total antioxidant status (TAS) and paraoxonase (PON1); tissue oxidative stress burden-prooxidative-antioxidative balance (PAB) and oxidative stress index (OSI); oxidative tissue damage-malondialdehyde (MDA) and advanced oxidation protein products (AOPP). All oximes were able to attenuate DDVP-induced oxidative stress in rat plasma and brain. Changes of determined parameters in brain were not as prominent as it was seen in plasma. Based on OSI, better abilities of oxime K027, K203 and obidoxime to maintain DDVP-induced oxidative stress in rat brain were shown as compared to trimedoxime, pralidoxime and asoxime. Oximes can influence the complex in vivo redox processes that might contribute to their overall therapeutic efficacy. Further research is needed to understand the underlying molecular mechanisms involved in this phenomenon.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Archives of Toxicology",
title = "Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain",
volume = "92",
number = "2",
pages = "745-757",
doi = "10.1007/s00204-017-2101-z"
}

Antonijević, E., Kotur-Stevuljević, J., Musilek, K., Kosvancova, A., Kuca, K., Đukić-Ćosić, D., Spasojević-Kalimanovska, V.,& Antonijević, B.. (2018). Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain. in Archives of Toxicology
Springer Heidelberg, Heidelberg., 92(2), 745-757.
https://doi.org/10.1007/s00204-017-2101-z

Antonijević E, Kotur-Stevuljević J, Musilek K, Kosvancova A, Kuca K, Đukić-Ćosić D, Spasojević-Kalimanovska V, Antonijević B. Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain. in Archives of Toxicology. 2018;92(2):745-757.
doi:10.1007/s00204-017-2101-z .

Antonijević, Evica, Kotur-Stevuljević, Jelena, Musilek, Kamil, Kosvancova, Andrea, Kuca, Kamil, Đukić-Ćosić, Danijela, Spasojević-Kalimanovska, Vesna, Antonijević, Biljana, "Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain" in Archives of Toxicology, 92, no. 2 (2018):745-757,
https://doi.org/10.1007/s00204-017-2101-z . .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Musilek, Kamil
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Ćurčić, Marijana
AU  - Čupić-Miladinović, Dejana
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3055
AB  - Inhibition of acethylcholinesterase (AChE) as a key molecular event induced by organophosphate (OP) pesticides and nerve agents presents a human health concern. In efficacy testing of experimental oximes, potential antidotes in OP poisoning, reactivation of OP-inhibited AChE is used as specific endpoint. However, according to our best knowledge, so far oximes have not been quantitatively evaluated by comprehensive benchmark dose (BMD) approach, that would improve both identification and quantification of the effect and allow more rigorous comparison of efficacies. Thus, we have examined in vivo dose-response relationship for two promising experimental oximes, K203 and K027, concerning reactivation of erythrocyte AChE inhibited by dichlorvos (DDVP). Groups of Wistar rats were treated with six different doses of oximes (i.m) immediately after DDVP challenge (s.c) and AChE was measured 60 min later. Dose-response modeling was done by PROAST software 65.5 (RIVM, The Nederlands). BMD-covariate method resulted in four-parameter model from both exponential and Hill model families as the best estimate of relationship between AChE activity and oxime dose, with potency parameter being oxime-dependent. Oxime K027 was shown to be 1.929-fold more potent considering that 58% increase in AChE activity was achived with the dose BMD58-K027 = 52 mu mol/kg in contrast to BMD58-K203 = 100 mu mol/kg.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Food and Chemical Toxicology
T1  - Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes
VL  - 121
SP  - 224
EP  - 230
DO  - 10.1016/j.fct.2018.08.065
ER  - 

@article{
author = "Antonijević, Evica and Musilek, Kamil and Kuca, Kamil and Đukić-Ćosić, Danijela and Ćurčić, Marijana and Čupić-Miladinović, Dejana and Bulat, Zorica and Antonijević, Biljana",
year = "2018",
abstract = "Inhibition of acethylcholinesterase (AChE) as a key molecular event induced by organophosphate (OP) pesticides and nerve agents presents a human health concern. In efficacy testing of experimental oximes, potential antidotes in OP poisoning, reactivation of OP-inhibited AChE is used as specific endpoint. However, according to our best knowledge, so far oximes have not been quantitatively evaluated by comprehensive benchmark dose (BMD) approach, that would improve both identification and quantification of the effect and allow more rigorous comparison of efficacies. Thus, we have examined in vivo dose-response relationship for two promising experimental oximes, K203 and K027, concerning reactivation of erythrocyte AChE inhibited by dichlorvos (DDVP). Groups of Wistar rats were treated with six different doses of oximes (i.m) immediately after DDVP challenge (s.c) and AChE was measured 60 min later. Dose-response modeling was done by PROAST software 65.5 (RIVM, The Nederlands). BMD-covariate method resulted in four-parameter model from both exponential and Hill model families as the best estimate of relationship between AChE activity and oxime dose, with potency parameter being oxime-dependent. Oxime K027 was shown to be 1.929-fold more potent considering that 58% increase in AChE activity was achived with the dose BMD58-K027 = 52 mu mol/kg in contrast to BMD58-K203 = 100 mu mol/kg.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Food and Chemical Toxicology",
title = "Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes",
volume = "121",
pages = "224-230",
doi = "10.1016/j.fct.2018.08.065"
}

Antonijević, E., Musilek, K., Kuca, K., Đukić-Ćosić, D., Ćurčić, M., Čupić-Miladinović, D., Bulat, Z.,& Antonijević, B.. (2018). Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes. in Food and Chemical Toxicology
Pergamon-Elsevier Science Ltd, Oxford., 121, 224-230.
https://doi.org/10.1016/j.fct.2018.08.065

Antonijević E, Musilek K, Kuca K, Đukić-Ćosić D, Ćurčić M, Čupić-Miladinović D, Bulat Z, Antonijević B. Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes. in Food and Chemical Toxicology. 2018;121:224-230.
doi:10.1016/j.fct.2018.08.065 .

Antonijević, Evica, Musilek, Kamil, Kuca, Kamil, Đukić-Ćosić, Danijela, Ćurčić, Marijana, Čupić-Miladinović, Dejana, Bulat, Zorica, Antonijević, Biljana, "Dose-response modeling of reactivating potency of oximes K027 and K203 against a direct acetylcholinesterase inhibitor in rat erythrocytes" in Food and Chemical Toxicology, 121 (2018):224-230,
https://doi.org/10.1016/j.fct.2018.08.065 . .

TY  - CONF
AU  - Antonijević, Evica
AU  - Kotur-Stevuljević, Jelena
AU  - Musilek, Kamil
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2895
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Effect of six oximes on total oxidant and antioxidant status in brain of rats intoxicated with a direct acethylcholinesterase inhibitor
VL  - 280
IS  - Supplement 1
SP  - S90
EP  - S90
DO  - 10.1016/j.toxlet.2017.07.250
ER  - 

@conference{
author = "Antonijević, Evica and Kotur-Stevuljević, Jelena and Musilek, Kamil and Kuca, Kamil and Đukić-Ćosić, Danijela and Antonijević, Biljana",
year = "2017",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Effect of six oximes on total oxidant and antioxidant status in brain of rats intoxicated with a direct acethylcholinesterase inhibitor",
volume = "280",
number = "Supplement 1",
pages = "S90-S90",
doi = "10.1016/j.toxlet.2017.07.250"
}

Antonijević, E., Kotur-Stevuljević, J., Musilek, K., Kuca, K., Đukić-Ćosić, D.,& Antonijević, B.. (2017). Effect of six oximes on total oxidant and antioxidant status in brain of rats intoxicated with a direct acethylcholinesterase inhibitor. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 280(Supplement 1), S90-S90.
https://doi.org/10.1016/j.toxlet.2017.07.250

Antonijević E, Kotur-Stevuljević J, Musilek K, Kuca K, Đukić-Ćosić D, Antonijević B. Effect of six oximes on total oxidant and antioxidant status in brain of rats intoxicated with a direct acethylcholinesterase inhibitor. in Toxicology Letters. 2017;280(Supplement 1):S90-S90.
doi:10.1016/j.toxlet.2017.07.250 .

Antonijević, Evica, Kotur-Stevuljević, Jelena, Musilek, Kamil, Kuca, Kamil, Đukić-Ćosić, Danijela, Antonijević, Biljana, "Effect of six oximes on total oxidant and antioxidant status in brain of rats intoxicated with a direct acethylcholinesterase inhibitor" in Toxicology Letters, 280, no. Supplement 1 (2017):S90-S90,
https://doi.org/10.1016/j.toxlet.2017.07.250 . .

TY  - JOUR
AU  - Antonijević, Evica
AU  - Musilek, Kamil
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Vučinić, Slavica
AU  - Antonijević, Biljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2655
AB  - As oxime-based structures are the only causal antidotes to organophosphate (OP)-inhibited acetylcholinesterase (AChE), the majority of studies on these have been directed towards their synthesis and testing. In this study, experimental bispyridinium oximes K027 and K203, which have shown promising results in the last decade of research, were examined in vivo for their therapeutic and reactivating ability in acute poisoning by the direct AChE-inhibitor dichlorvos (DDVP), used as a dimethyl OP structural model. Additionally, the efficacy of oximes K027 and K203 was compared with the efficacy of four oximes (pralidoxime, trimedoxime, obidoxime and HI-6), already used in efficacy experiments and human medicine. To evaluate therapeutic efficacy, groups of Wistar rats were treated with equitoxic doses of oximes (5% LD50, i.m.) and/or atropine (10 mg/kg, i.m.) immediately after s.c. DDVP challenge (4-6 doses). Using the same antidotal protocol, AChE activity was measured in erythrocytes, diaphragm and brain 60 min after s.c. DDVP exposure (75% LD50). The oxime K027 was the most efficacious in reducing the DDVP induced lethal effect in rats, while the oxime K203 was more efficacious than trimedoxime, pralidoxime and HI-6. Significant reactivation of DDVP inhibited AChE was achieved only with oxime K027 or its combination with atropine in erythocytes and the diaphragm. Moreover, the acute i.m. toxicity of oxime K027 in rats was lower than all other tested oximes. The results of this study support previous studies considering the oxime K027 as a promising experimental oxime structure for further testing against structurally-different OP compounds.
PB  - Elsevier Science BV, Amsterdam
T2  - Neurotoxicology
T1  - Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor
VL  - 55
SP  - 33
EP  - 39
DO  - 10.1016/j.neuro.2016.05.006
ER  - 

@article{
author = "Antonijević, Evica and Musilek, Kamil and Kuca, Kamil and Đukić-Ćosić, Danijela and Vučinić, Slavica and Antonijević, Biljana",
year = "2016",
abstract = "As oxime-based structures are the only causal antidotes to organophosphate (OP)-inhibited acetylcholinesterase (AChE), the majority of studies on these have been directed towards their synthesis and testing. In this study, experimental bispyridinium oximes K027 and K203, which have shown promising results in the last decade of research, were examined in vivo for their therapeutic and reactivating ability in acute poisoning by the direct AChE-inhibitor dichlorvos (DDVP), used as a dimethyl OP structural model. Additionally, the efficacy of oximes K027 and K203 was compared with the efficacy of four oximes (pralidoxime, trimedoxime, obidoxime and HI-6), already used in efficacy experiments and human medicine. To evaluate therapeutic efficacy, groups of Wistar rats were treated with equitoxic doses of oximes (5% LD50, i.m.) and/or atropine (10 mg/kg, i.m.) immediately after s.c. DDVP challenge (4-6 doses). Using the same antidotal protocol, AChE activity was measured in erythrocytes, diaphragm and brain 60 min after s.c. DDVP exposure (75% LD50). The oxime K027 was the most efficacious in reducing the DDVP induced lethal effect in rats, while the oxime K203 was more efficacious than trimedoxime, pralidoxime and HI-6. Significant reactivation of DDVP inhibited AChE was achieved only with oxime K027 or its combination with atropine in erythocytes and the diaphragm. Moreover, the acute i.m. toxicity of oxime K027 in rats was lower than all other tested oximes. The results of this study support previous studies considering the oxime K027 as a promising experimental oxime structure for further testing against structurally-different OP compounds.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Neurotoxicology",
title = "Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor",
volume = "55",
pages = "33-39",
doi = "10.1016/j.neuro.2016.05.006"
}

Antonijević, E., Musilek, K., Kuca, K., Đukić-Ćosić, D., Vučinić, S.,& Antonijević, B.. (2016). Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor. in Neurotoxicology
Elsevier Science BV, Amsterdam., 55, 33-39.
https://doi.org/10.1016/j.neuro.2016.05.006

Antonijević E, Musilek K, Kuca K, Đukić-Ćosić D, Vučinić S, Antonijević B. Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor. in Neurotoxicology. 2016;55:33-39.
doi:10.1016/j.neuro.2016.05.006 .

Antonijević, Evica, Musilek, Kamil, Kuca, Kamil, Đukić-Ćosić, Danijela, Vučinić, Slavica, Antonijević, Biljana, "Therapeutic and reactivating efficacy of oximes K027 and K203 against a direct acetylcholinesterase inhibitor" in Neurotoxicology, 55 (2016):33-39,
https://doi.org/10.1016/j.neuro.2016.05.006 . .

TY  - CONF
AU  - Antonijević, Evica
AU  - Musilek, Kamil
AU  - Kuca, Kamil
AU  - Đukić-Ćosić, Danijela
AU  - Ćurčić, Marijana
AU  - Brkić, Dragica
AU  - Antonijević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2342
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Ability of oxime K027 to reactivate brain AChE in rats acutely poisoned by a direct acetylcholinesterase inhibitor
VL  - 238
IS  - 2, Supplement
SP  - S339
EP  - S340
DO  - 10.1016/j.toxlet.2015.08.968
ER  - 

@conference{
author = "Antonijević, Evica and Musilek, Kamil and Kuca, Kamil and Đukić-Ćosić, Danijela and Ćurčić, Marijana and Brkić, Dragica and Antonijević, Biljana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Ability of oxime K027 to reactivate brain AChE in rats acutely poisoned by a direct acetylcholinesterase inhibitor",
volume = "238",
number = "2, Supplement",
pages = "S339-S340",
doi = "10.1016/j.toxlet.2015.08.968"
}

Antonijević, E., Musilek, K., Kuca, K., Đukić-Ćosić, D., Ćurčić, M., Brkić, D.,& Antonijević, B.. (2015). Ability of oxime K027 to reactivate brain AChE in rats acutely poisoned by a direct acetylcholinesterase inhibitor. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S339-S340.
https://doi.org/10.1016/j.toxlet.2015.08.968

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Antonijević, Evica, Musilek, Kamil, Kuca, Kamil, Đukić-Ćosić, Danijela, Ćurčić, Marijana, Brkić, Dragica, Antonijević, Biljana, "Ability of oxime K027 to reactivate brain AChE in rats acutely poisoned by a direct acetylcholinesterase inhibitor" in Toxicology Letters, 238, no. 2, Supplement (2015):S339-S340,
https://doi.org/10.1016/j.toxlet.2015.08.968 . .