Milosavljević, Slobodan

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  • Milosavljević, Slobodan (9)
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Author's Bibliography

Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge

Mandić, Boris M.; Vlajić, Marina D.; Trifunović, Snežana; Simić, Milena; Vujisić, Ljubodrag V.; Vucković, Ivan M.; Novaković, Miroslav; Nikolić-Mandić, Snežana D.; Tešević, Vele; Vajs, Vlatka; Milosavljević, Slobodan

(Taylor & Francis Ltd, Abingdon, 2015)

TY  - JOUR
AU  - Mandić, Boris M.
AU  - Vlajić, Marina D.
AU  - Trifunović, Snežana
AU  - Simić, Milena
AU  - Vujisić, Ljubodrag V.
AU  - Vucković, Ivan M.
AU  - Novaković, Miroslav
AU  - Nikolić-Mandić, Snežana D.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2412
AB  - Procedure for isolation of pyrrolizidine alkaloids (PAs) from Rindera umbellata Bunge plant species was optimised. Different extraction media (methanol, ethanol and sulphuric acid), concentration and volume of sulphuric acid, pH of PA solution for alkaline extraction, extraction time and techniques (maceration, ultrasonic and overhead rotary mixer assisted extraction) were investigated. The yields of six PAs (7-angeloyl heliotridane, 7-angeloyl heliotridine, lindelofine, 7-angeloyl rinderine, punctanecine and heliosupine) were monitored by GC-MS/FID. The best results for the isolation all of six PAs were obtained when the extraction was performed with 1M sulphuric acid (30mL per 1.00g of dried sample) by overhead rotary mixer during three days. Optimal pH value for alkaline extraction of PAs with CH2Cl2 was 9, and the extraction should be performed with four portions of 30mL of CH2Cl2. This procedure could be also useful for a plant sample preparation for GC and LC analyses of PAs.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge
VL  - 29
IS  - 9
SP  - 887
EP  - 890
DO  - 10.1080/14786419.2014.991929
ER  - 
@article{
author = "Mandić, Boris M. and Vlajić, Marina D. and Trifunović, Snežana and Simić, Milena and Vujisić, Ljubodrag V. and Vucković, Ivan M. and Novaković, Miroslav and Nikolić-Mandić, Snežana D. and Tešević, Vele and Vajs, Vlatka and Milosavljević, Slobodan",
year = "2015",
abstract = "Procedure for isolation of pyrrolizidine alkaloids (PAs) from Rindera umbellata Bunge plant species was optimised. Different extraction media (methanol, ethanol and sulphuric acid), concentration and volume of sulphuric acid, pH of PA solution for alkaline extraction, extraction time and techniques (maceration, ultrasonic and overhead rotary mixer assisted extraction) were investigated. The yields of six PAs (7-angeloyl heliotridane, 7-angeloyl heliotridine, lindelofine, 7-angeloyl rinderine, punctanecine and heliosupine) were monitored by GC-MS/FID. The best results for the isolation all of six PAs were obtained when the extraction was performed with 1M sulphuric acid (30mL per 1.00g of dried sample) by overhead rotary mixer during three days. Optimal pH value for alkaline extraction of PAs with CH2Cl2 was 9, and the extraction should be performed with four portions of 30mL of CH2Cl2. This procedure could be also useful for a plant sample preparation for GC and LC analyses of PAs.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge",
volume = "29",
number = "9",
pages = "887-890",
doi = "10.1080/14786419.2014.991929"
}
Mandić, B. M., Vlajić, M. D., Trifunović, S., Simić, M., Vujisić, L. V., Vucković, I. M., Novaković, M., Nikolić-Mandić, S. D., Tešević, V., Vajs, V.,& Milosavljević, S.. (2015). Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 29(9), 887-890.
https://doi.org/10.1080/14786419.2014.991929
Mandić BM, Vlajić MD, Trifunović S, Simić M, Vujisić LV, Vucković IM, Novaković M, Nikolić-Mandić SD, Tešević V, Vajs V, Milosavljević S. Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge. in Natural Product Research. 2015;29(9):887-890.
doi:10.1080/14786419.2014.991929 .
Mandić, Boris M., Vlajić, Marina D., Trifunović, Snežana, Simić, Milena, Vujisić, Ljubodrag V., Vucković, Ivan M., Novaković, Miroslav, Nikolić-Mandić, Snežana D., Tešević, Vele, Vajs, Vlatka, Milosavljević, Slobodan, "Optimisation of isolation procedure for pyrrolizidine alkaloids from Rindera umbellata Bunge" in Natural Product Research, 29, no. 9 (2015):887-890,
https://doi.org/10.1080/14786419.2014.991929 . .
16
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Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization

Mandić, Boris M.; Simić, Milena; Vucković, Ivan M.; Vujisić, Ljubodrag V.; Novaković, Miroslav; Trifunović, Snežana; Nikolić-Mandić, Snežana D.; Tešević, Vele; Vajs, Vlatka; Milosavljević, Slobodan

(MDPI, Basel, 2013)

TY  - JOUR
AU  - Mandić, Boris M.
AU  - Simić, Milena
AU  - Vucković, Ivan M.
AU  - Vujisić, Ljubodrag V.
AU  - Novaković, Miroslav
AU  - Trifunović, Snežana
AU  - Nikolić-Mandić, Snežana D.
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1894
AB  - The examination of the aerial parts, roots, and seeds of the endemic plant Rindera umbellata is reported in this paper for the first time. Phytochemical investigation of R. umbellata led to the isolation and characterization of ten pyrrolizidine alkaloids and eleven fatty acids in the form of triglycerides. Pyrrolizidine alkaloids 1-9 were found in the aerial parts, 7 and 8 in the roots, and 6-10, together with eleven fatty acids, in the seeds of this plant species. The structures of compounds 1-10 were established based on spectroscopic studies (H-1- and C-13-NMR, 2D NMR, IR and CI-MS). After trans-esterification, methyl esters of the fatty acids were analyzed using GC-MS. The effect of lindelofine-N-oxide (7) on tubulin polymerization was determined.
PB  - MDPI, Basel
T2  - Molecules
T1  - Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization
VL  - 18
IS  - 9
SP  - 10694
EP  - 10706
DO  - 10.3390/molecules180910694
ER  - 
@article{
author = "Mandić, Boris M. and Simić, Milena and Vucković, Ivan M. and Vujisić, Ljubodrag V. and Novaković, Miroslav and Trifunović, Snežana and Nikolić-Mandić, Snežana D. and Tešević, Vele and Vajs, Vlatka and Milosavljević, Slobodan",
year = "2013",
abstract = "The examination of the aerial parts, roots, and seeds of the endemic plant Rindera umbellata is reported in this paper for the first time. Phytochemical investigation of R. umbellata led to the isolation and characterization of ten pyrrolizidine alkaloids and eleven fatty acids in the form of triglycerides. Pyrrolizidine alkaloids 1-9 were found in the aerial parts, 7 and 8 in the roots, and 6-10, together with eleven fatty acids, in the seeds of this plant species. The structures of compounds 1-10 were established based on spectroscopic studies (H-1- and C-13-NMR, 2D NMR, IR and CI-MS). After trans-esterification, methyl esters of the fatty acids were analyzed using GC-MS. The effect of lindelofine-N-oxide (7) on tubulin polymerization was determined.",
publisher = "MDPI, Basel",
journal = "Molecules",
title = "Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization",
volume = "18",
number = "9",
pages = "10694-10706",
doi = "10.3390/molecules180910694"
}
Mandić, B. M., Simić, M., Vucković, I. M., Vujisić, L. V., Novaković, M., Trifunović, S., Nikolić-Mandić, S. D., Tešević, V., Vajs, V.,& Milosavljević, S.. (2013). Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization. in Molecules
MDPI, Basel., 18(9), 10694-10706.
https://doi.org/10.3390/molecules180910694
Mandić BM, Simić M, Vucković IM, Vujisić LV, Novaković M, Trifunović S, Nikolić-Mandić SD, Tešević V, Vajs V, Milosavljević S. Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization. in Molecules. 2013;18(9):10694-10706.
doi:10.3390/molecules180910694 .
Mandić, Boris M., Simić, Milena, Vucković, Ivan M., Vujisić, Ljubodrag V., Novaković, Miroslav, Trifunović, Snežana, Nikolić-Mandić, Snežana D., Tešević, Vele, Vajs, Vlatka, Milosavljević, Slobodan, "Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization" in Molecules, 18, no. 9 (2013):10694-10706,
https://doi.org/10.3390/molecules180910694 . .
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Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity

Zdunić, Gordana; Gođevac, Dejan; Šavikin, Katarina; Novaković, Miroslav; Milosavljević, Slobodan; Petrović, Silvana

(Taylor & Francis Ltd, Abingdon, 2011)

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Gođevac, Dejan
AU  - Šavikin, Katarina
AU  - Novaković, Miroslav
AU  - Milosavljević, Slobodan
AU  - Petrović, Silvana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1542
AB  - The chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three myricetin-3-O-glycosides, 3-O- and 5-O-caffeoylquinic acid, quercetin, I3,II8-biapigenin, pseudohypericin and hypericin were identified. The constituents of the extracts were quantified using HPLC-DAD (high-performance liquid chromatography-diode array detector). Isolation of the compounds from n-BuOH and EtOAc extracts was conducted by column chromatography. Antioxidant capacity of the extracts was evaluated by superoxide radical and ABTS root+ scavenging assays and inhibition of lipid peroxidation. The EtOAc extract of H. richeri was the most potent antioxidant in all experiments. Free radical scavenging compounds were identified by HPLC-DPPH root (high-performance liquid chromatography-2,2-diphenyl-1-picrylhydrazyl) post-column derivatisation method, where all phenolic compounds except I3,II8-biapigenin exhibited radical scavenging properties. This is the first report of the presence of myricetin-3-O-rutinoside, myricetin-3-O-galactoside, myricetin-3-O-glucoside, 5-O-caffeoylquinic acid and I3,II8-biapigenin in H. richeri.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Natural Product Research
T1  - Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity
VL  - 25
IS  - 3
SP  - 175
EP  - 187
DO  - 10.1080/14786410802401390
ER  - 
@article{
author = "Zdunić, Gordana and Gođevac, Dejan and Šavikin, Katarina and Novaković, Miroslav and Milosavljević, Slobodan and Petrović, Silvana",
year = "2011",
abstract = "The chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three myricetin-3-O-glycosides, 3-O- and 5-O-caffeoylquinic acid, quercetin, I3,II8-biapigenin, pseudohypericin and hypericin were identified. The constituents of the extracts were quantified using HPLC-DAD (high-performance liquid chromatography-diode array detector). Isolation of the compounds from n-BuOH and EtOAc extracts was conducted by column chromatography. Antioxidant capacity of the extracts was evaluated by superoxide radical and ABTS root+ scavenging assays and inhibition of lipid peroxidation. The EtOAc extract of H. richeri was the most potent antioxidant in all experiments. Free radical scavenging compounds were identified by HPLC-DPPH root (high-performance liquid chromatography-2,2-diphenyl-1-picrylhydrazyl) post-column derivatisation method, where all phenolic compounds except I3,II8-biapigenin exhibited radical scavenging properties. This is the first report of the presence of myricetin-3-O-rutinoside, myricetin-3-O-galactoside, myricetin-3-O-glucoside, 5-O-caffeoylquinic acid and I3,II8-biapigenin in H. richeri.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Natural Product Research",
title = "Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity",
volume = "25",
number = "3",
pages = "175-187",
doi = "10.1080/14786410802401390"
}
Zdunić, G., Gođevac, D., Šavikin, K., Novaković, M., Milosavljević, S.,& Petrović, S.. (2011). Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity. in Natural Product Research
Taylor & Francis Ltd, Abingdon., 25(3), 175-187.
https://doi.org/10.1080/14786410802401390
Zdunić G, Gođevac D, Šavikin K, Novaković M, Milosavljević S, Petrović S. Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity. in Natural Product Research. 2011;25(3):175-187.
doi:10.1080/14786410802401390 .
Zdunić, Gordana, Gođevac, Dejan, Šavikin, Katarina, Novaković, Miroslav, Milosavljević, Slobodan, Petrović, Silvana, "Isolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacity" in Natural Product Research, 25, no. 3 (2011):175-187,
https://doi.org/10.1080/14786410802401390 . .
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11

Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro

Mandić, Boris M.; Gođevac, Dejan; Beškoski, Vladimir P.; Simić, Milena; Trifunović, Snežana; Tešević, Vele; Vajs, Vlatka; Milosavljević, Slobodan

(Srpsko hemijsko društvo, Beograd, 2009)

TY  - JOUR
AU  - Mandić, Boris M.
AU  - Gođevac, Dejan
AU  - Beškoski, Vladimir P.
AU  - Simić, Milena
AU  - Trifunović, Snežana
AU  - Tešević, Vele
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1297
AB  - The genus Senecio (family Asteraceae) is one of the largest in the world. It comprises about 1100 species which are the rich source of pyrrolizidine alkaloids. Plants containing pyrrolizidine alkaloids are among the most important sources of human and animal exposure to plant toxins and carcinogens. The pyrrolizidine alkaloids of seven Senecio species (S. erucifolius, S. othonnae, S. wagneri, S. subalpinus, S. carpathicus, S. paludosus and S. rupestris) were studied. Fourteen alkaloids were isolated and their structures determined from spectroscopic data (1H- and 13C-NMR, IR and MS). Five of them were identified in S. erucifolius, four in S. othonnae, two in S. wagneri, four in S. subalpinus, two in S. carpathicus, three in S. paludosus and three in S. rupestris. Seven pyrrolizidine alkaloids were found for the first time in particular species. The results have chemotaxonomic importance. The cytotoxic activity and antimicrobial activity of some alkaloids were also studied.
AB  - Jedan od najbrojnijih rodova na svetu je rod Senecio (familija Asteraceae). Obuhvata oko 1100 vrsta koje predstavljaju bogat izvor pirolizidinskih alkaloida. Najznačajnija izloženost ljudi i životinja biljnim toksinima i karcinogenima potiče od biljaka koje sadrže pirolizidinske alkaloide. U ovom radu izolovani su pirolizidinski alkaloidi iz sedam vrsta roda Senecio (S. erucifolius, S. othonnae, S. wagneri, S. subalpinus, S. carpathicus, S. paludosus i S. rupestris), a njihove strukture određene na bazi spektroskopskih podataka (1H- i 13C-NMR, IR i MS). Izolovano je ukupno 14 alkaloida, pet iz S. erucifolius, četiri iz S. othonnae, dva iz S. wagneri, četiri iz S. subalpinus, dva iz S. carpathicus, tri iz S. paludosus i tri iz S. rupestris. Sedam pirolizidinskih alkaloida je po prvi put izolovano iz nekih pojedinačnih vrsta. Dobijeni rezultati imaju hemotaksonomski značaj. Ispitana je citotoksičnost i antimikrobna aktivnost izolovanih alkaloida.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro
T1  - Pirolizidinski alkaloidi iz sedam samoniklih biljnih vrsta roda Senecio koje rastu u Srbiji i Crnoj Gori
VL  - 74
IS  - 1
SP  - 27
EP  - 34
DO  - 10.2298/JSC0901027M
ER  - 
@article{
author = "Mandić, Boris M. and Gođevac, Dejan and Beškoski, Vladimir P. and Simić, Milena and Trifunović, Snežana and Tešević, Vele and Vajs, Vlatka and Milosavljević, Slobodan",
year = "2009",
abstract = "The genus Senecio (family Asteraceae) is one of the largest in the world. It comprises about 1100 species which are the rich source of pyrrolizidine alkaloids. Plants containing pyrrolizidine alkaloids are among the most important sources of human and animal exposure to plant toxins and carcinogens. The pyrrolizidine alkaloids of seven Senecio species (S. erucifolius, S. othonnae, S. wagneri, S. subalpinus, S. carpathicus, S. paludosus and S. rupestris) were studied. Fourteen alkaloids were isolated and their structures determined from spectroscopic data (1H- and 13C-NMR, IR and MS). Five of them were identified in S. erucifolius, four in S. othonnae, two in S. wagneri, four in S. subalpinus, two in S. carpathicus, three in S. paludosus and three in S. rupestris. Seven pyrrolizidine alkaloids were found for the first time in particular species. The results have chemotaxonomic importance. The cytotoxic activity and antimicrobial activity of some alkaloids were also studied., Jedan od najbrojnijih rodova na svetu je rod Senecio (familija Asteraceae). Obuhvata oko 1100 vrsta koje predstavljaju bogat izvor pirolizidinskih alkaloida. Najznačajnija izloženost ljudi i životinja biljnim toksinima i karcinogenima potiče od biljaka koje sadrže pirolizidinske alkaloide. U ovom radu izolovani su pirolizidinski alkaloidi iz sedam vrsta roda Senecio (S. erucifolius, S. othonnae, S. wagneri, S. subalpinus, S. carpathicus, S. paludosus i S. rupestris), a njihove strukture određene na bazi spektroskopskih podataka (1H- i 13C-NMR, IR i MS). Izolovano je ukupno 14 alkaloida, pet iz S. erucifolius, četiri iz S. othonnae, dva iz S. wagneri, četiri iz S. subalpinus, dva iz S. carpathicus, tri iz S. paludosus i tri iz S. rupestris. Sedam pirolizidinskih alkaloida je po prvi put izolovano iz nekih pojedinačnih vrsta. Dobijeni rezultati imaju hemotaksonomski značaj. Ispitana je citotoksičnost i antimikrobna aktivnost izolovanih alkaloida.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro, Pirolizidinski alkaloidi iz sedam samoniklih biljnih vrsta roda Senecio koje rastu u Srbiji i Crnoj Gori",
volume = "74",
number = "1",
pages = "27-34",
doi = "10.2298/JSC0901027M"
}
Mandić, B. M., Gođevac, D., Beškoski, V. P., Simić, M., Trifunović, S., Tešević, V., Vajs, V.,& Milosavljević, S.. (2009). Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 74(1), 27-34.
https://doi.org/10.2298/JSC0901027M
Mandić BM, Gođevac D, Beškoski VP, Simić M, Trifunović S, Tešević V, Vajs V, Milosavljević S. Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro. in Journal of the Serbian Chemical Society. 2009;74(1):27-34.
doi:10.2298/JSC0901027M .
Mandić, Boris M., Gođevac, Dejan, Beškoski, Vladimir P., Simić, Milena, Trifunović, Snežana, Tešević, Vele, Vajs, Vlatka, Milosavljević, Slobodan, "Pyrrolizidine alkaloids from seven wild-growing Senecio species in Serbia and Montenegro" in Journal of the Serbian Chemical Society, 74, no. 1 (2009):27-34,
https://doi.org/10.2298/JSC0901027M . .
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Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine

Mitić, Dragana; Milenković, Marina; Milosavljević, Slobodan; Gođevac, Dejan; Miodragović, Zoran M.; Anđelković, Katarina; Miodragović, Djenana

(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)

TY  - JOUR
AU  - Mitić, Dragana
AU  - Milenković, Marina
AU  - Milosavljević, Slobodan
AU  - Gođevac, Dejan
AU  - Miodragović, Zoran M.
AU  - Anđelković, Katarina
AU  - Miodragović, Djenana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1222
AB  - In this paper the first complexes of M2+ ions (M2+ = Zn2+, Cd2+ and Co2+) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and H-1, C-13 and N-15 NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine
VL  - 44
IS  - 4
SP  - 1537
EP  - 1544
DO  - 10.1016/j.ejmech.2008.07.017
ER  - 
@article{
author = "Mitić, Dragana and Milenković, Marina and Milosavljević, Slobodan and Gođevac, Dejan and Miodragović, Zoran M. and Anđelković, Katarina and Miodragović, Djenana",
year = "2009",
abstract = "In this paper the first complexes of M2+ ions (M2+ = Zn2+, Cd2+ and Co2+) with N-benzyloxycarbonyl-S-phenylalaninato ligand (1-3) are described. The new complexes were characterized by means of elemental analysis, IR and UV-vis spectroscopy, molar conductivity measurements and H-1, C-13 and N-15 NMR spectroscopy (1D and 2D). The Co(II) complex adopts an octahedral geometry, and the Zn(II) and Cd(II) complexes adopt a tetrahedral one. For the first time, the antimicrobial activity of N-benzyloxycarbonyl-S-phenylalaninato ligand (N-Boc-S-phe) and the complexes 1-3 was investigated against Gram-positive: Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Bacillus subtilis and Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and two strains of the yeast Candida albicans. It was shown that the complexes were effective against most strains. The best activity was detected against the yeast C. albicans.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine",
volume = "44",
number = "4",
pages = "1537-1544",
doi = "10.1016/j.ejmech.2008.07.017"
}
Mitić, D., Milenković, M., Milosavljević, S., Gođevac, D., Miodragović, Z. M., Anđelković, K.,& Miodragović, D.. (2009). Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 44(4), 1537-1544.
https://doi.org/10.1016/j.ejmech.2008.07.017
Mitić D, Milenković M, Milosavljević S, Gođevac D, Miodragović ZM, Anđelković K, Miodragović D. Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. in European Journal of Medicinal Chemistry. 2009;44(4):1537-1544.
doi:10.1016/j.ejmech.2008.07.017 .
Mitić, Dragana, Milenković, Marina, Milosavljević, Slobodan, Gođevac, Dejan, Miodragović, Zoran M., Anđelković, Katarina, Miodragović, Djenana, "Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine" in European Journal of Medicinal Chemistry, 44, no. 4 (2009):1537-1544,
https://doi.org/10.1016/j.ejmech.2008.07.017 . .
8
8
13

Chemical composition of Tanacetum larvatum essential oil

Bulatović, Vanja M.; Vajs, Vlatka; Aljancić, Ivana T.; Milosavljević, Slobodan; Đoković, Dejan D.; Petrović, Silvana

(Allured Publ Corp, Carol Stream, 2006)

TY  - JOUR
AU  - Bulatović, Vanja M.
AU  - Vajs, Vlatka
AU  - Aljancić, Ivana T.
AU  - Milosavljević, Slobodan
AU  - Đoković, Dejan D.
AU  - Petrović, Silvana
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/855
AB  - Tanacetum larvatum (Gris.) Kanitz. is an endemic perennial herb distributed on a rocky terrain in Serbia(Kosovo), Montenegro and Albania. The chemical composition of T larvatum essential oil, obtained from two locations in Montenegro (Mt. Komovi [Sample II] and Mt. Prokletije [Sample II]) was investigated. The oils obtained by hydrodistillation were analyzed by GC and GC/MS, on the two different capillary columns. The aerial parts of T. larvatum yielded 0.3% and 0.2% of a yellowish oil (Sample I and Sample II, respectively). About 40 compounds were identified, representing similar to 89% and 96% of the total oil content in the Samples I and II, respectively. tran's-Sabinyl acetate was found to be the dominant component (51.2% and 69.7%). Among the rest of compounds beta-pinene (7.7% and 4.3%) and camphor (6.3% and 4.3%) were the most abundant in both samples.
PB  - Allured Publ Corp, Carol Stream
T2  - Journal of Essential Oil Research
T1  - Chemical composition of Tanacetum larvatum essential oil
VL  - 18
IS  - 2
SP  - 126
EP  - 128
DO  - 10.1080/10412905.2006.9699040
ER  - 
@article{
author = "Bulatović, Vanja M. and Vajs, Vlatka and Aljancić, Ivana T. and Milosavljević, Slobodan and Đoković, Dejan D. and Petrović, Silvana",
year = "2006",
abstract = "Tanacetum larvatum (Gris.) Kanitz. is an endemic perennial herb distributed on a rocky terrain in Serbia(Kosovo), Montenegro and Albania. The chemical composition of T larvatum essential oil, obtained from two locations in Montenegro (Mt. Komovi [Sample II] and Mt. Prokletije [Sample II]) was investigated. The oils obtained by hydrodistillation were analyzed by GC and GC/MS, on the two different capillary columns. The aerial parts of T. larvatum yielded 0.3% and 0.2% of a yellowish oil (Sample I and Sample II, respectively). About 40 compounds were identified, representing similar to 89% and 96% of the total oil content in the Samples I and II, respectively. tran's-Sabinyl acetate was found to be the dominant component (51.2% and 69.7%). Among the rest of compounds beta-pinene (7.7% and 4.3%) and camphor (6.3% and 4.3%) were the most abundant in both samples.",
publisher = "Allured Publ Corp, Carol Stream",
journal = "Journal of Essential Oil Research",
title = "Chemical composition of Tanacetum larvatum essential oil",
volume = "18",
number = "2",
pages = "126-128",
doi = "10.1080/10412905.2006.9699040"
}
Bulatović, V. M., Vajs, V., Aljancić, I. T., Milosavljević, S., Đoković, D. D.,& Petrović, S.. (2006). Chemical composition of Tanacetum larvatum essential oil. in Journal of Essential Oil Research
Allured Publ Corp, Carol Stream., 18(2), 126-128.
https://doi.org/10.1080/10412905.2006.9699040
Bulatović VM, Vajs V, Aljancić IT, Milosavljević S, Đoković DD, Petrović S. Chemical composition of Tanacetum larvatum essential oil. in Journal of Essential Oil Research. 2006;18(2):126-128.
doi:10.1080/10412905.2006.9699040 .
Bulatović, Vanja M., Vajs, Vlatka, Aljancić, Ivana T., Milosavljević, Slobodan, Đoković, Dejan D., Petrović, Silvana, "Chemical composition of Tanacetum larvatum essential oil" in Journal of Essential Oil Research, 18, no. 2 (2006):126-128,
https://doi.org/10.1080/10412905.2006.9699040 . .
3
4
6

Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels

Vajs, Vlatka; Milosavljević, Slobodan; Tešević, Vele; Živanović, Predrag; Jančić, Radiša; Todorović, Branislava; Slavkovska, Violeta

(Taylor & Francis, 1995)

TY  - JOUR
AU  - Vajs, Vlatka
AU  - Milosavljević, Slobodan
AU  - Tešević, Vele
AU  - Živanović, Predrag
AU  - Jančić, Radiša
AU  - Todorović, Branislava
AU  - Slavkovska, Violeta
PY  - 1995
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3480
AB  - Essential oils of ripe fruits and umbels of Chaerophyllum coloraturn L.(Apiaceae) were found by GC and GC/MS to contain very high percentage of (E)--β-farnesene.
(79.21% and 68.40% respectively).
PB  - Taylor & Francis
T2  - Journal of Essential Oil Research
T1  - Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels
VL  - 5
IS  - 7
SP  - 529
EP  - 531
DO  - 10.1080/10412905.1995.9698578
ER  - 
@article{
author = "Vajs, Vlatka and Milosavljević, Slobodan and Tešević, Vele and Živanović, Predrag and Jančić, Radiša and Todorović, Branislava and Slavkovska, Violeta",
year = "1995",
abstract = "Essential oils of ripe fruits and umbels of Chaerophyllum coloraturn L.(Apiaceae) were found by GC and GC/MS to contain very high percentage of (E)--β-farnesene.
(79.21% and 68.40% respectively).",
publisher = "Taylor & Francis",
journal = "Journal of Essential Oil Research",
title = "Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels",
volume = "5",
number = "7",
pages = "529-531",
doi = "10.1080/10412905.1995.9698578"
}
Vajs, V., Milosavljević, S., Tešević, V., Živanović, P., Jančić, R., Todorović, B.,& Slavkovska, V.. (1995). Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels. in Journal of Essential Oil Research
Taylor & Francis., 5(7), 529-531.
https://doi.org/10.1080/10412905.1995.9698578
Vajs V, Milosavljević S, Tešević V, Živanović P, Jančić R, Todorović B, Slavkovska V. Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels. in Journal of Essential Oil Research. 1995;5(7):529-531.
doi:10.1080/10412905.1995.9698578 .
Vajs, Vlatka, Milosavljević, Slobodan, Tešević, Vele, Živanović, Predrag, Jančić, Radiša, Todorović, Branislava, Slavkovska, Violeta, "Chaerophyllum coloratum L.: Essential Oils of Ripe Fruits and Umbels" in Journal of Essential Oil Research, 5, no. 7 (1995):529-531,
https://doi.org/10.1080/10412905.1995.9698578 . .
24
28

Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae)

Živanović, Predrag; Đoković, Dejan; Vajs, Vlatka; Slavkovska, Violeta; Todorović, Branislava; Milosavljević, Slobodan

(Govi-Verlag, 1994)

TY  - JOUR
AU  - Živanović, Predrag
AU  - Đoković, Dejan
AU  - Vajs, Vlatka
AU  - Slavkovska, Violeta
AU  - Todorović, Branislava
AU  - Milosavljević, Slobodan
PY  - 1994
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3477
PB  - Govi-Verlag
T2  - Die Pharmazie
T1  - Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae)
VL  - 6
IS  - 49
SP  - 463
EP  - 463
UR  - https://hdl.handle.net/21.15107/rcub_farfar_3477
ER  - 
@article{
author = "Živanović, Predrag and Đoković, Dejan and Vajs, Vlatka and Slavkovska, Violeta and Todorović, Branislava and Milosavljević, Slobodan",
year = "1994",
publisher = "Govi-Verlag",
journal = "Die Pharmazie",
title = "Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae)",
volume = "6",
number = "49",
pages = "463-463",
url = "https://hdl.handle.net/21.15107/rcub_farfar_3477"
}
Živanović, P., Đoković, D., Vajs, V., Slavkovska, V., Todorović, B.,& Milosavljević, S.. (1994). Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae). in Die Pharmazie
Govi-Verlag., 6(49), 463-463.
https://hdl.handle.net/21.15107/rcub_farfar_3477
Živanović P, Đoković D, Vajs V, Slavkovska V, Todorović B, Milosavljević S. Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae). in Die Pharmazie. 1994;6(49):463-463.
https://hdl.handle.net/21.15107/rcub_farfar_3477 .
Živanović, Predrag, Đoković, Dejan, Vajs, Vlatka, Slavkovska, Violeta, Todorović, Branislava, Milosavljević, Slobodan, "Essential oils of flowers and fruits of Athamanta haynaldii Borb. et Uchtr. (Apiaceae)" in Die Pharmazie, 6, no. 49 (1994):463-463,
https://hdl.handle.net/21.15107/rcub_farfar_3477 .
9

Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum

Milosavljević, Slobodan; Jeremić, Dragan; Nevešćanin, Marina; Radovanović, Gorica; Živanović, Predrag; Todorović, Branislava; Slavkovska, Violeta; Vajs, Vlatka

(1993)

TY  - JOUR
AU  - Milosavljević, Slobodan
AU  - Jeremić, Dragan
AU  - Nevešćanin, Marina
AU  - Radovanović, Gorica
AU  - Živanović, Predrag
AU  - Todorović, Branislava
AU  - Slavkovska, Violeta
AU  - Vajs, Vlatka
PY  - 1993
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3475
AB  - An investigation of the coumarin content of plant species Angelica silvestris (roots and fruits) and Peucedanum austriacum (Jacq.) Koch (roots), both belonging to the family Apiaceae is reported. A. silvestris contained only linear furocoumarins (four in the roots and five in the fruits), two of them (heraclenol and heraclenin) found for the first time in this species. The photoactive compound bergapten (also known as 5-methoxypsoralen) was also among the isolated coumarins. In P. austriacum only reduced (dihydro) coumarins were detected (four compunds): linear dihydrofurocoumarins, deltoin and sekorin, an angular dihydrofurocoumarin, zosimin and a linear dihydropyranoeoumarin, agasyllin. None of them has been found before in this plant species.
T2  - Journal of the Serbian Chemical Society
T1  - Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum
VL  - 12
IS  - 58
SP  - 997
EP  - 1001
UR  - https://hdl.handle.net/21.15107/rcub_farfar_3475
ER  - 
@article{
author = "Milosavljević, Slobodan and Jeremić, Dragan and Nevešćanin, Marina and Radovanović, Gorica and Živanović, Predrag and Todorović, Branislava and Slavkovska, Violeta and Vajs, Vlatka",
year = "1993",
abstract = "An investigation of the coumarin content of plant species Angelica silvestris (roots and fruits) and Peucedanum austriacum (Jacq.) Koch (roots), both belonging to the family Apiaceae is reported. A. silvestris contained only linear furocoumarins (four in the roots and five in the fruits), two of them (heraclenol and heraclenin) found for the first time in this species. The photoactive compound bergapten (also known as 5-methoxypsoralen) was also among the isolated coumarins. In P. austriacum only reduced (dihydro) coumarins were detected (four compunds): linear dihydrofurocoumarins, deltoin and sekorin, an angular dihydrofurocoumarin, zosimin and a linear dihydropyranoeoumarin, agasyllin. None of them has been found before in this plant species.",
journal = "Journal of the Serbian Chemical Society",
title = "Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum",
volume = "12",
number = "58",
pages = "997-1001",
url = "https://hdl.handle.net/21.15107/rcub_farfar_3475"
}
Milosavljević, S., Jeremić, D., Nevešćanin, M., Radovanović, G., Živanović, P., Todorović, B., Slavkovska, V.,& Vajs, V.. (1993). Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum. in Journal of the Serbian Chemical Society, 12(58), 997-1001.
https://hdl.handle.net/21.15107/rcub_farfar_3475
Milosavljević S, Jeremić D, Nevešćanin M, Radovanović G, Živanović P, Todorović B, Slavkovska V, Vajs V. Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum. in Journal of the Serbian Chemical Society. 1993;12(58):997-1001.
https://hdl.handle.net/21.15107/rcub_farfar_3475 .
Milosavljević, Slobodan, Jeremić, Dragan, Nevešćanin, Marina, Radovanović, Gorica, Živanović, Predrag, Todorović, Branislava, Slavkovska, Violeta, Vajs, Vlatka, "Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum" in Journal of the Serbian Chemical Society, 12, no. 58 (1993):997-1001,
https://hdl.handle.net/21.15107/rcub_farfar_3475 .