TY  - JOUR
AU  - Veinović, Gorana
AU  - Stojić-Vukanić, Zorica
AU  - Antić-Stanković, Jelena
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2524
AB  - Lyme borreliosis is a multisystem disorder characterized by a wide spectrum of clinical manifestations. In Europe, the main aetiological agents are Borrelia afzelii, Borrelia garinii and B. burgdorferi sensu stricto, but Borrelia spielmanii, Borrelia valaisiana, Borrelia lusitaniae and Borrelia bissettii have also been reported as rare or potential causes of human disease. In North America, B. burgdorferi sensu stricto is the only human pathogen. The most common clinical manifestation of Lyme borreliosis is a skin lesion, erythema migrans, which may resolve spontaneously without antibiotic treatment. However, the pathogen can spread to other tissues and organs, causing more severe manifestations that can involve a skin, nervous system, joints, and/or heart, requiring antibiotic therapy. The most commonly used antibiotics in the treatment of Lyme borreliosis are: amoxicillin, ceftriaxone, cefuroxime, doxycycline and azithromycin.
AB  - Lajmska borelioza je multisistemska bolest koju karakteriše širok spektar kliničkih manifestacija. U Evropi je primarno prouzrokovana vrstama B. afzelii, B. garinii i B. burgdorferi sensu stricto, ali Borrelia spielmanii, Borrelia valaisiana, Borrelia lusitaniae and Borrelia bissettii se takođe navode kao retki ili potencijalni uzročnici oboljenja kod ljudi. U Severnoj Americi, kao jedini humani patogen, dokazana je vrsta B. burgdorferi sensu stricto. Najčešća klinička manifestacija lajmske borelioze je kožna lezija, erythema migrans, koja može da prođe spontano, bez terapije antibioticima. Međutim, patogen se može širiti do drugih delova kože i organa i tako prouzrokovati teže manifestacije kako na koži, tako i na nervnom sistemu, zglobovima i/ili srcu, pri čemu je terapija antibioticima neophodna. Najčešće korišćeni antibiotici u terapiji lajmske borelioze su: amoksicilin, ceftriakson, cefuroksim, doksiciklin i azitromicin.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Lyme borreliosis: Epidemiology, clinical manifestations and treatment
T1  - Lajmska borelioza - epidemiologija, klinička slika i terapija
VL  - 65
IS  - 2
SP  - 129
EP  - 146
DO  - 10.5937/arhfarm1502129V
ER  - 

@article{
author = "Veinović, Gorana and Stojić-Vukanić, Zorica and Antić-Stanković, Jelena",
year = "2015",
abstract = "Lyme borreliosis is a multisystem disorder characterized by a wide spectrum of clinical manifestations. In Europe, the main aetiological agents are Borrelia afzelii, Borrelia garinii and B. burgdorferi sensu stricto, but Borrelia spielmanii, Borrelia valaisiana, Borrelia lusitaniae and Borrelia bissettii have also been reported as rare or potential causes of human disease. In North America, B. burgdorferi sensu stricto is the only human pathogen. The most common clinical manifestation of Lyme borreliosis is a skin lesion, erythema migrans, which may resolve spontaneously without antibiotic treatment. However, the pathogen can spread to other tissues and organs, causing more severe manifestations that can involve a skin, nervous system, joints, and/or heart, requiring antibiotic therapy. The most commonly used antibiotics in the treatment of Lyme borreliosis are: amoxicillin, ceftriaxone, cefuroxime, doxycycline and azithromycin., Lajmska borelioza je multisistemska bolest koju karakteriše širok spektar kliničkih manifestacija. U Evropi je primarno prouzrokovana vrstama B. afzelii, B. garinii i B. burgdorferi sensu stricto, ali Borrelia spielmanii, Borrelia valaisiana, Borrelia lusitaniae and Borrelia bissettii se takođe navode kao retki ili potencijalni uzročnici oboljenja kod ljudi. U Severnoj Americi, kao jedini humani patogen, dokazana je vrsta B. burgdorferi sensu stricto. Najčešća klinička manifestacija lajmske borelioze je kožna lezija, erythema migrans, koja može da prođe spontano, bez terapije antibioticima. Međutim, patogen se može širiti do drugih delova kože i organa i tako prouzrokovati teže manifestacije kako na koži, tako i na nervnom sistemu, zglobovima i/ili srcu, pri čemu je terapija antibioticima neophodna. Najčešće korišćeni antibiotici u terapiji lajmske borelioze su: amoksicilin, ceftriakson, cefuroksim, doksiciklin i azitromicin.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Lyme borreliosis: Epidemiology, clinical manifestations and treatment, Lajmska borelioza - epidemiologija, klinička slika i terapija",
volume = "65",
number = "2",
pages = "129-146",
doi = "10.5937/arhfarm1502129V"
}

Veinović, G., Stojić-Vukanić, Z.,& Antić-Stanković, J.. (2015). Lyme borreliosis: Epidemiology, clinical manifestations and treatment. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(2), 129-146.
https://doi.org/10.5937/arhfarm1502129V

Veinović G, Stojić-Vukanić Z, Antić-Stanković J. Lyme borreliosis: Epidemiology, clinical manifestations and treatment. in Arhiv za farmaciju. 2015;65(2):129-146.
doi:10.5937/arhfarm1502129V .

Veinović, Gorana, Stojić-Vukanić, Zorica, Antić-Stanković, Jelena, "Lyme borreliosis: Epidemiology, clinical manifestations and treatment" in Arhiv za farmaciju, 65, no. 2 (2015):129-146,
https://doi.org/10.5937/arhfarm1502129V . .

TY  - JOUR
AU  - Veinović, Gorana
AU  - Filipić, Brankica
AU  - Stanković, Jelena
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2067
AB  - Lyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex. Borreliae are fastidious, slow-growing and biochemically inactive bacteria that need special attention and optimal conditions for cultivation. The isolation of Borrelia from clinical material and their cultivation is a time-consuming and demanding procedure. Cultivation lasts from 9 up to 12 weeks, which is much longer than is necessary to grow most other human bacterial pathogens. Although B. burgdorferi sensu lato is susceptible to a wide range of antimicrobial agents in vitro, up to now the susceptibility of individual Borrelia species to antibiotics is defined only partially.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review
VL  - 65
IS  - 2
SP  - 533
EP  - 547
DO  - 10.2298/ABS1302533V
ER  - 

@article{
author = "Veinović, Gorana and Filipić, Brankica and Stanković, Jelena",
year = "2013",
abstract = "Lyme borreliosis is the most common vector-borne disease in the northern hemisphere. The agents of Lyme borreliosis are borrelia, bacteria of the family Spirochaetaceae, which are grouped in Borrelia burgdorferi sensu lato species complex. Borreliae are fastidious, slow-growing and biochemically inactive bacteria that need special attention and optimal conditions for cultivation. The isolation of Borrelia from clinical material and their cultivation is a time-consuming and demanding procedure. Cultivation lasts from 9 up to 12 weeks, which is much longer than is necessary to grow most other human bacterial pathogens. Although B. burgdorferi sensu lato is susceptible to a wide range of antimicrobial agents in vitro, up to now the susceptibility of individual Borrelia species to antibiotics is defined only partially.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review",
volume = "65",
number = "2",
pages = "533-547",
doi = "10.2298/ABS1302533V"
}

Veinović, G., Filipić, B.,& Stanković, J.. (2013). Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 65(2), 533-547.
https://doi.org/10.2298/ABS1302533V

Veinović G, Filipić B, Stanković J. Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review. in Archives of Biological Sciences. 2013;65(2):533-547.
doi:10.2298/ABS1302533V .

Veinović, Gorana, Filipić, Brankica, Stanković, Jelena, "Isolation, cultivation, and in vitro susceptibility testing of Borrelia burgdorferi sensu lato: A review" in Archives of Biological Sciences, 65, no. 2 (2013):533-547,
https://doi.org/10.2298/ABS1302533V . .