TY  - JOUR
AU  - Peruničić-Peković, Gordana
AU  - Rasić, Zorica
AU  - Plješa, Steva
AU  - Šobajić, Slađana
AU  - Đuričić, Ivana
AU  - Maletić, Radojka
AU  - Ristić-Medić, Danijela K.
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/990
AB  - Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.
PB  - Wiley, Hoboken
T2  - Nephrology
T1  - Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients
VL  - 12
IS  - 4
SP  - 331
EP  - 336
DO  - 10.1111/j.1440-1797.2007.00777.x
ER  - 

@article{
author = "Peruničić-Peković, Gordana and Rasić, Zorica and Plješa, Steva and Šobajić, Slađana and Đuričić, Ivana and Maletić, Radojka and Ristić-Medić, Danijela K.",
year = "2007",
abstract = "Aims: Nutrition as an aetiological factor participates a great deal in premature atherosclerosis in haemodialysis (HD) patients. The basic mechanisms of end-stage renal disease and premature atherosclerosis are connected with changes in cell functions at the membrane level. We investigated the red cell membrane fatty acids and the effects of fish oil supplements on nutritional status and inflammatory markers in HD patients. Methods: We examined 42 HD patients (mean age 55 +/- 8 years). The control group consisted of 16 healthy subjects of similar age and sex to the tested group. HD patients were administered supplements with 2.4 g of n-3 polyunsaturated fatty acids per day for 2 months. Before and after supplementation, we examined plasma lipids, cell membrane erythrocyte phospholipids content, serum albumin, haemoglobin, interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-alpha). Results: Baseline values in the tested group confirmed the presence of essential fatty acids deficiency. A statistically significant negative correlation between TNF-alpha and eicosapentaenoic acid (EPA) (r=-0.497; P  lt  0.05) and IL-6 and EPA (r=-468; P=0.03) was found in HD patients before supplementation. There was a significant increase in docosahexaenoic acids, high density lipoprotein cholesterol, plasma albumin, haemoglobin levels in HD patients after supplementation (P=0.0001). There was a significant increase in EPA (P=0.01) after treatment, and there was a significant decrease in inflammatory markers (IL-6 and TNF-alpha, P=0.0001) after supplementation in the tested group. Conclusion: A dietary regime with fish oil could be used in dialysis patients to slow down the development of atherosclerosis and improve nutritional parameters.",
publisher = "Wiley, Hoboken",
journal = "Nephrology",
title = "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients",
volume = "12",
number = "4",
pages = "331-336",
doi = "10.1111/j.1440-1797.2007.00777.x"
}

Peruničić-Peković, G., Rasić, Z., Plješa, S., Šobajić, S., Đuričić, I., Maletić, R.,& Ristić-Medić, D. K.. (2007). Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology
Wiley, Hoboken., 12(4), 331-336.
https://doi.org/10.1111/j.1440-1797.2007.00777.x

Peruničić-Peković G, Rasić Z, Plješa S, Šobajić S, Đuričić I, Maletić R, Ristić-Medić DK. Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients. in Nephrology. 2007;12(4):331-336.
doi:10.1111/j.1440-1797.2007.00777.x .

Peruničić-Peković, Gordana, Rasić, Zorica, Plješa, Steva, Šobajić, Slađana, Đuričić, Ivana, Maletić, Radojka, Ristić-Medić, Danijela K., "Effect of n-3 fatty acids on nutritional status and inflammatory markers in haemodialysis patients" in Nephrology, 12, no. 4 (2007):331-336,
https://doi.org/10.1111/j.1440-1797.2007.00777.x . .

TY  - JOUR
AU  - Rakić, Sveto
AU  - Povrenović, Dragan
AU  - Tešević, Vele
AU  - Simić, Mirjana
AU  - Maletić, Radojka
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5233
AB  - In this paper, are presented the results of physical and chemical investigations of differently treated samples of oak acorn. The aim of this investigation is to estimate the influence of thermal treatment on physical and nutritive characteristics of investigated samples. Oak acorn, Quercus robur, (belonging to Fagaceae family) was investigated in native and thermally treated forms. By subsequent extraction of dry toasted oak acorn (Quercus semen tostum) the aqueous extract was obtained which is then dried in a spout-fluid bed. The content of total polyphenols, then polyphenols unadsorbed on hide powder and tannins was determined by spectrophotometric methods with phosphor-wolfram acid according to Ph. Yug. V. Galic acid was determined by HPLC. The total antioxidant activity (TAA) of the aqueous extract compared to the control samples of pigs fat and synthetic antioxidant butylated hydroxyanisole BHA was estimated by Schall–Oven test at 60 ± 1 °C in dark, and oxidative changes were determined by measuring the Peroxide value (PV). For determination of macro- and microelements the method of AAS was used.

By detecting the changes of PV it is established that aqueous extract was influencing the stability of pigs fat, that is, showing the antioxidant activity. The activity was increasing with increasing concentration in tested samples. The obtained results regarding the total polyphenols content, the content of galic acid, nitrogen compounds, macro and microelements show that acorn, after treatment, was retaining and in some cases improving its functional properties.
PB  - Elsevier
T2  - Journal of Food Engineering
T1  - Oak Acorn, Polyphenols and Antioxidant Activity in Functional Food
VL  - 74
IS  - 3
SP  - 416
EP  - 423
DO  - 10.1016/j.jfoodeng.2005.03.057
ER  - 

@article{
author = "Rakić, Sveto and Povrenović, Dragan and Tešević, Vele and Simić, Mirjana and Maletić, Radojka",
year = "2006",
abstract = "In this paper, are presented the results of physical and chemical investigations of differently treated samples of oak acorn. The aim of this investigation is to estimate the influence of thermal treatment on physical and nutritive characteristics of investigated samples. Oak acorn, Quercus robur, (belonging to Fagaceae family) was investigated in native and thermally treated forms. By subsequent extraction of dry toasted oak acorn (Quercus semen tostum) the aqueous extract was obtained which is then dried in a spout-fluid bed. The content of total polyphenols, then polyphenols unadsorbed on hide powder and tannins was determined by spectrophotometric methods with phosphor-wolfram acid according to Ph. Yug. V. Galic acid was determined by HPLC. The total antioxidant activity (TAA) of the aqueous extract compared to the control samples of pigs fat and synthetic antioxidant butylated hydroxyanisole BHA was estimated by Schall–Oven test at 60 ± 1 °C in dark, and oxidative changes were determined by measuring the Peroxide value (PV). For determination of macro- and microelements the method of AAS was used.

By detecting the changes of PV it is established that aqueous extract was influencing the stability of pigs fat, that is, showing the antioxidant activity. The activity was increasing with increasing concentration in tested samples. The obtained results regarding the total polyphenols content, the content of galic acid, nitrogen compounds, macro and microelements show that acorn, after treatment, was retaining and in some cases improving its functional properties.",
publisher = "Elsevier",
journal = "Journal of Food Engineering",
title = "Oak Acorn, Polyphenols and Antioxidant Activity in Functional Food",
volume = "74",
number = "3",
pages = "416-423",
doi = "10.1016/j.jfoodeng.2005.03.057"
}

Rakić, S., Povrenović, D., Tešević, V., Simić, M.,& Maletić, R.. (2006). Oak Acorn, Polyphenols and Antioxidant Activity in Functional Food. in Journal of Food Engineering
Elsevier., 74(3), 416-423.
https://doi.org/10.1016/j.jfoodeng.2005.03.057

Rakić S, Povrenović D, Tešević V, Simić M, Maletić R. Oak Acorn, Polyphenols and Antioxidant Activity in Functional Food. in Journal of Food Engineering. 2006;74(3):416-423.
doi:10.1016/j.jfoodeng.2005.03.057 .

Rakić, Sveto, Povrenović, Dragan, Tešević, Vele, Simić, Mirjana, Maletić, Radojka, "Oak Acorn, Polyphenols and Antioxidant Activity in Functional Food" in Journal of Food Engineering, 74, no. 3 (2006):416-423,
https://doi.org/10.1016/j.jfoodeng.2005.03.057 . .