TY  - JOUR
AU  - Popović, Dejana
AU  - Damjanović, Svetozar
AU  - Popović, Bojana
AU  - Kocijančić, Aleksandar
AU  - Labudović, Dragana
AU  - Seman, Stefan
AU  - Stojiljković, Stanimir
AU  - Tesić, Milorad
AU  - Arena, Ross
AU  - Lasica, Ratko
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4020
AB  - Anticipation of stress induces physiological, behavioral and cognitive adjustments that are required for an appropriate response to the upcoming situation. Additional research examining the response of cardiopulmonary parameters and stress hormones during anticipation of stress in different chronic stress adaptive models is needed. As an addition to our previous research, a total of 57 subjects (16 elite male wrestlers, 21 water polo player and 20 sedentary subjects matched for age) were analyzed. Cardiopulmonary exercise testing (CPET) on a treadmill was used as the laboratory stress model; peak oxygen consumption (VO2) was obtained during CPET. Plasma levels of adrenocorticotropic hormone (ACTH), cortisol, alpha-melanocyte stimulating hormone (alpha-MSH) and N-terminal-pro-B type natriuretic peptide (NT-pro-BNP) were measured by radioimmunometric, radioimmunoassay and immunoassay sandwich technique, respectively, together with cardiopulmonary measurements, 10 minutes pre-CPET and at the initiation of CPET. The response of diastolic blood pressure and heart rate was different between groups during stress anticipation (p¼0.019, 0.049, respectively), while systolic blood pressure, peak VO2 and carbon-dioxide production responses were similar. ACTH and cortisol increased during the experimental condition, NT-pro-BNP decreased and alpha-MSH remained unchanged. All groups had similar hormonal responses during stress anticipation with the exception of the ACTH/cortisol ratio. In all three groups, DNT-pro-BNP during stress anticipation was the best independent predictor of peak VO2 (B¼36.01, r¼0.37, p¼0.001). In conclusion, the type of chronic stress exposure influences the hemodynamic response during anticipation of physical stress and the path of hormonal stress axis activation. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition. LAY SUMMARY The study revealed differences in hormonal and hemodynamic responses during anticipation of stress between athletes and sedentary participants. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition. Abbreviations: ACTH: adrenocorticitropic hormone; BSA: body surface area; BW: body weight; C: controls; CPET: cardiopulmonary exercise test; DBP: diastolic arterial blood pressure; FFM: fat-free mass; FM: fat mass; HR: heart rate; MSH: melanocyte-stimulating hormone; NT-pro-BNP: N terminal-pro-B type natriuretic peptide; SBP: systolic arterial blood pressure; VCO2: carbon dioxide production; VE: minute ventilation; VO2: oxygen consumption; W: wrestlers; WP: water polo players
PB  - Taylor and Francis Ltd.
T2  - Stress
T1  - Physiological behavior during stress anticipation across different chronic stress exposure adaptive models
DO  - 10.1080/10253890.2021.2006178
ER  - 

@article{
author = "Popović, Dejana and Damjanović, Svetozar and Popović, Bojana and Kocijančić, Aleksandar and Labudović, Dragana and Seman, Stefan and Stojiljković, Stanimir and Tesić, Milorad and Arena, Ross and Lasica, Ratko",
year = "2021",
abstract = "Anticipation of stress induces physiological, behavioral and cognitive adjustments that are required for an appropriate response to the upcoming situation. Additional research examining the response of cardiopulmonary parameters and stress hormones during anticipation of stress in different chronic stress adaptive models is needed. As an addition to our previous research, a total of 57 subjects (16 elite male wrestlers, 21 water polo player and 20 sedentary subjects matched for age) were analyzed. Cardiopulmonary exercise testing (CPET) on a treadmill was used as the laboratory stress model; peak oxygen consumption (VO2) was obtained during CPET. Plasma levels of adrenocorticotropic hormone (ACTH), cortisol, alpha-melanocyte stimulating hormone (alpha-MSH) and N-terminal-pro-B type natriuretic peptide (NT-pro-BNP) were measured by radioimmunometric, radioimmunoassay and immunoassay sandwich technique, respectively, together with cardiopulmonary measurements, 10 minutes pre-CPET and at the initiation of CPET. The response of diastolic blood pressure and heart rate was different between groups during stress anticipation (p¼0.019, 0.049, respectively), while systolic blood pressure, peak VO2 and carbon-dioxide production responses were similar. ACTH and cortisol increased during the experimental condition, NT-pro-BNP decreased and alpha-MSH remained unchanged. All groups had similar hormonal responses during stress anticipation with the exception of the ACTH/cortisol ratio. In all three groups, DNT-pro-BNP during stress anticipation was the best independent predictor of peak VO2 (B¼36.01, r¼0.37, p¼0.001). In conclusion, the type of chronic stress exposure influences the hemodynamic response during anticipation of physical stress and the path of hormonal stress axis activation. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition. LAY SUMMARY The study revealed differences in hormonal and hemodynamic responses during anticipation of stress between athletes and sedentary participants. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition. Abbreviations: ACTH: adrenocorticitropic hormone; BSA: body surface area; BW: body weight; C: controls; CPET: cardiopulmonary exercise test; DBP: diastolic arterial blood pressure; FFM: fat-free mass; FM: fat mass; HR: heart rate; MSH: melanocyte-stimulating hormone; NT-pro-BNP: N terminal-pro-B type natriuretic peptide; SBP: systolic arterial blood pressure; VCO2: carbon dioxide production; VE: minute ventilation; VO2: oxygen consumption; W: wrestlers; WP: water polo players",
publisher = "Taylor and Francis Ltd.",
journal = "Stress",
title = "Physiological behavior during stress anticipation across different chronic stress exposure adaptive models",
doi = "10.1080/10253890.2021.2006178"
}

Popović, D., Damjanović, S., Popović, B., Kocijančić, A., Labudović, D., Seman, S., Stojiljković, S., Tesić, M., Arena, R.,& Lasica, R.. (2021). Physiological behavior during stress anticipation across different chronic stress exposure adaptive models. in Stress
Taylor and Francis Ltd...
https://doi.org/10.1080/10253890.2021.2006178

Popović D, Damjanović S, Popović B, Kocijančić A, Labudović D, Seman S, Stojiljković S, Tesić M, Arena R, Lasica R. Physiological behavior during stress anticipation across different chronic stress exposure adaptive models. in Stress. 2021;.
doi:10.1080/10253890.2021.2006178 .

Popović, Dejana, Damjanović, Svetozar, Popović, Bojana, Kocijančić, Aleksandar, Labudović, Dragana, Seman, Stefan, Stojiljković, Stanimir, Tesić, Milorad, Arena, Ross, Lasica, Ratko, "Physiological behavior during stress anticipation across different chronic stress exposure adaptive models" in Stress (2021),
https://doi.org/10.1080/10253890.2021.2006178 . .

TY  - JOUR
AU  - Kojić, Filip
AU  - Ranisavljev, Igor
AU  - Ćosić, Dušan
AU  - Popović, Dejana
AU  - Stojiljković, Stanimir
AU  - Ilić, Vladimir
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3945
AB  - The aim of the study was to compare the effects of two different training protocols, which differ in the duration of the eccentric phase, on the one-repetition maximum (1RM), thickness and contractile properties of elbow flexors. Twenty untrained college students were randomly divided into two experimental groups, based on the training tempo: FEG (Faster Eccentric Group: 1/0/1/0) and SEG (Slower Eccentric Group: 4/0/1/0). Training intervention was a biceps bending exercise, conducted twice a week for 7 weeks. The intensity (60–70% RM), sets (3–4) and rest intervals (120 s) were held constant, while repetitions were performed until it was not possible to maintain a set duration. In the initial and final measurements, 1RM, muscle thickness and tensiomyography parameters – contraction time (Tc) and radial deformation (Dm) – were evaluated. An ANCOVA model (using baseline outcomes as covariates) was applied to determine between-group differences at post-test, while Pearson’s product-moment correlation coefficient was used to investigate the relationship between absolute changes in muscle thickness and Dm. Muscle strength increase was greater for SEG than for FEG (6.0 ± 1.76 vs. 3.30 ± 2.26 kg, p < 0.01). In both groups muscle thickness increased equally (FEG: 3.24 ± 2.01 vs. SEG: 3.57 ± 1.17 mm, p < 0.01), while an overall reduction in Dm was observed (FEG: 1.99 ± 1.20 vs. SEG: 2.26 ± 1.03 mm, p < 0.01). Values of Tc remained unchanged. A significant negative relationship was observed between changes in muscle thickness and Dm (r = -0.763, Adj.R² = 0.560, p < 0.01). These results indicate that the duration of the eccentric phase has no effect on muscle hypertrophy in untrained subjects, but that slower eccentric movement significantly increases 1RM.
PB  - Institute of Sport
T2  - Biology of Sport
T1  - Effects of resistance training on hypertrophy, strength and tensiomyography parameters of elbow flexors: Role of eccentric phase duration
VL  - 38
IS  - 4
SP  - 587
EP  - 594
DO  - 10.5114/biolsport.2021.99323
ER  - 

@article{
author = "Kojić, Filip and Ranisavljev, Igor and Ćosić, Dušan and Popović, Dejana and Stojiljković, Stanimir and Ilić, Vladimir",
year = "2021",
abstract = "The aim of the study was to compare the effects of two different training protocols, which differ in the duration of the eccentric phase, on the one-repetition maximum (1RM), thickness and contractile properties of elbow flexors. Twenty untrained college students were randomly divided into two experimental groups, based on the training tempo: FEG (Faster Eccentric Group: 1/0/1/0) and SEG (Slower Eccentric Group: 4/0/1/0). Training intervention was a biceps bending exercise, conducted twice a week for 7 weeks. The intensity (60–70% RM), sets (3–4) and rest intervals (120 s) were held constant, while repetitions were performed until it was not possible to maintain a set duration. In the initial and final measurements, 1RM, muscle thickness and tensiomyography parameters – contraction time (Tc) and radial deformation (Dm) – were evaluated. An ANCOVA model (using baseline outcomes as covariates) was applied to determine between-group differences at post-test, while Pearson’s product-moment correlation coefficient was used to investigate the relationship between absolute changes in muscle thickness and Dm. Muscle strength increase was greater for SEG than for FEG (6.0 ± 1.76 vs. 3.30 ± 2.26 kg, p < 0.01). In both groups muscle thickness increased equally (FEG: 3.24 ± 2.01 vs. SEG: 3.57 ± 1.17 mm, p < 0.01), while an overall reduction in Dm was observed (FEG: 1.99 ± 1.20 vs. SEG: 2.26 ± 1.03 mm, p < 0.01). Values of Tc remained unchanged. A significant negative relationship was observed between changes in muscle thickness and Dm (r = -0.763, Adj.R² = 0.560, p < 0.01). These results indicate that the duration of the eccentric phase has no effect on muscle hypertrophy in untrained subjects, but that slower eccentric movement significantly increases 1RM.",
publisher = "Institute of Sport",
journal = "Biology of Sport",
title = "Effects of resistance training on hypertrophy, strength and tensiomyography parameters of elbow flexors: Role of eccentric phase duration",
volume = "38",
number = "4",
pages = "587-594",
doi = "10.5114/biolsport.2021.99323"
}

Kojić, F., Ranisavljev, I., Ćosić, D., Popović, D., Stojiljković, S.,& Ilić, V.. (2021). Effects of resistance training on hypertrophy, strength and tensiomyography parameters of elbow flexors: Role of eccentric phase duration. in Biology of Sport
Institute of Sport., 38(4), 587-594.
https://doi.org/10.5114/biolsport.2021.99323

Kojić F, Ranisavljev I, Ćosić D, Popović D, Stojiljković S, Ilić V. Effects of resistance training on hypertrophy, strength and tensiomyography parameters of elbow flexors: Role of eccentric phase duration. in Biology of Sport. 2021;38(4):587-594.
doi:10.5114/biolsport.2021.99323 .

Kojić, Filip, Ranisavljev, Igor, Ćosić, Dušan, Popović, Dejana, Stojiljković, Stanimir, Ilić, Vladimir, "Effects of resistance training on hypertrophy, strength and tensiomyography parameters of elbow flexors: Role of eccentric phase duration" in Biology of Sport, 38, no. 4 (2021):587-594,
https://doi.org/10.5114/biolsport.2021.99323 . .

TY  - JOUR
AU  - Milutinović, Katarina
AU  - Stojiljković, Stanimir
AU  - Ćuk, Jelena
AU  - Lasica, Ratko
AU  - Miosavljević, Andrej
AU  - Cvetković, Dimitrije
AU  - Trajković, Aleksandra
AU  - Pešić, Vesna
AU  - Arena, Ross
AU  - Popović, Dejana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3111
AB  - The athlete's heart is a set of morphological and functional characteristics that develop over time due to sports training. These adaptive changes result in increase in cardiac work efficiency and economy. They are manidested as cardiac muscle hypertrophy and dilation, with accompanying angiogenesis and slower heart rate, that are influenced by variable regulatory systems and genetic predisposition. The problem of sudden cardiac death in athletes, which persists despite numerous activities aimed at prevention, creates the need for a better definition of the athlete's heart, especially in terms of its differentiation from certain pathological conditions. This is of particular importance in the context of cardiac electrical activity. Right heart adaptations, hormonal regulatory mechanisms and the effects of nonphysiological adaptations during training, that may lead to pathologic alterations direction, are all relevant in the investigation of adverse cardiac events in athletes. In order to prevent sudden cardiac death in athletes, it is necessary to examine competitive athletes as well as apparently health individuals who recreationally exercise at a high volume. There are guidelines for mass screening and individual examinations, for all age groups and both genders, as well as for public service staff who require intense physical activity during their occupation. Both American and European recommendations require a detailed anamnesis and physical examination, whereas European, apart from that, require initial electrocardiography. The implementation of additional tests is necessary if the existence of any underlying pathophysiologic process is suspected. Checks should be performed before engaging in sports activities, as well as during training and competition periods.
AB  - Sportsko srce predstavlja efekat morfoloških i funkcionalnih adaptacija srca koje se razvijaju tokom vremena, pod uticajem sportskog treninga. Promene na srcu kod sportista za posledicu imaju promenu efikasnosti i ekonomičnosti srčanog rada. Manifestuju se hipertrofijom i dilatacijom srca, sa pratećom angiogenezom i usporenim srčanim radom, procesima koji su pod kontrolom različitih regulatornih sistema i genetske predispozicije. Problem iznenadne srčane smrti u sportu, čija se incidenca ne smanjuje uprkos brojnim aktivnostima koje se sprovode u cilju njene prevencije, nameće potrebu boljeg definisanja sportskog srca, naročito u smislu njegovog razlikovanja od pojedinih patoloških stanja. Kod izvesnog broja sportista uočavaju se promene električne aktivnosti, te je i u tom smislu potrebno razlikovati zdravo od bolesnog srca. Poslednjih godina posebno je u fokusu definisanje adaptivnih promena desnog srca. Dodatno, postoje nova saznanja o hormonskoj regulaciji adaptivnih promena srca sportista, a istražuju se i efekti nefizioloških manipulacija u trenažnom procesu koji mogu 'skrenuti' fiziološke procese u patološkom pravcu. U cilju prevencije iznenadne srčane smrti, neophodno je redovno pregledanje kako sportista, tako i fizički aktivnog dela populacije. Aktuelne preporuke daju smernice za masovne skrininge i individualne preglede sportista, za sve starosne grupe oba pola, kao i pripadnike javnih službi koje u opisu posla imaju intenzivne fizičke napore. Dok američke preporuke zahtevaju samo detaljnu anamnezu i fizikalni pregled, evropske preporuke zahtevaju i inicijalnu elektrokardiografiju. I evropske i američke preporuke zahtevaju sprovođenje dodatnih ispitivanja kod sumnje na postojanje bilo kakvog oboljenja. Ove preglede bi trebalo obavljati pre početka trenažnog procesa, kao i tokom perioda treniranja i takmičenja.
PB  - Univerzitet u Beogradu - Fakultet sporta i fizičkog vaspitanja, Beograd
T2  - Fizička kultura
T1  - Athlete's heart
T1  - Corazon de deportista
T1  - Sportsko srce
VL  - 72
IS  - 2
SP  - 139
EP  - 147
DO  - 10.5937/fizkul1802139M
ER  - 

@article{
author = "Milutinović, Katarina and Stojiljković, Stanimir and Ćuk, Jelena and Lasica, Ratko and Miosavljević, Andrej and Cvetković, Dimitrije and Trajković, Aleksandra and Pešić, Vesna and Arena, Ross and Popović, Dejana",
year = "2018",
abstract = "The athlete's heart is a set of morphological and functional characteristics that develop over time due to sports training. These adaptive changes result in increase in cardiac work efficiency and economy. They are manidested as cardiac muscle hypertrophy and dilation, with accompanying angiogenesis and slower heart rate, that are influenced by variable regulatory systems and genetic predisposition. The problem of sudden cardiac death in athletes, which persists despite numerous activities aimed at prevention, creates the need for a better definition of the athlete's heart, especially in terms of its differentiation from certain pathological conditions. This is of particular importance in the context of cardiac electrical activity. Right heart adaptations, hormonal regulatory mechanisms and the effects of nonphysiological adaptations during training, that may lead to pathologic alterations direction, are all relevant in the investigation of adverse cardiac events in athletes. In order to prevent sudden cardiac death in athletes, it is necessary to examine competitive athletes as well as apparently health individuals who recreationally exercise at a high volume. There are guidelines for mass screening and individual examinations, for all age groups and both genders, as well as for public service staff who require intense physical activity during their occupation. Both American and European recommendations require a detailed anamnesis and physical examination, whereas European, apart from that, require initial electrocardiography. The implementation of additional tests is necessary if the existence of any underlying pathophysiologic process is suspected. Checks should be performed before engaging in sports activities, as well as during training and competition periods., Sportsko srce predstavlja efekat morfoloških i funkcionalnih adaptacija srca koje se razvijaju tokom vremena, pod uticajem sportskog treninga. Promene na srcu kod sportista za posledicu imaju promenu efikasnosti i ekonomičnosti srčanog rada. Manifestuju se hipertrofijom i dilatacijom srca, sa pratećom angiogenezom i usporenim srčanim radom, procesima koji su pod kontrolom različitih regulatornih sistema i genetske predispozicije. Problem iznenadne srčane smrti u sportu, čija se incidenca ne smanjuje uprkos brojnim aktivnostima koje se sprovode u cilju njene prevencije, nameće potrebu boljeg definisanja sportskog srca, naročito u smislu njegovog razlikovanja od pojedinih patoloških stanja. Kod izvesnog broja sportista uočavaju se promene električne aktivnosti, te je i u tom smislu potrebno razlikovati zdravo od bolesnog srca. Poslednjih godina posebno je u fokusu definisanje adaptivnih promena desnog srca. Dodatno, postoje nova saznanja o hormonskoj regulaciji adaptivnih promena srca sportista, a istražuju se i efekti nefizioloških manipulacija u trenažnom procesu koji mogu 'skrenuti' fiziološke procese u patološkom pravcu. U cilju prevencije iznenadne srčane smrti, neophodno je redovno pregledanje kako sportista, tako i fizički aktivnog dela populacije. Aktuelne preporuke daju smernice za masovne skrininge i individualne preglede sportista, za sve starosne grupe oba pola, kao i pripadnike javnih službi koje u opisu posla imaju intenzivne fizičke napore. Dok američke preporuke zahtevaju samo detaljnu anamnezu i fizikalni pregled, evropske preporuke zahtevaju i inicijalnu elektrokardiografiju. I evropske i američke preporuke zahtevaju sprovođenje dodatnih ispitivanja kod sumnje na postojanje bilo kakvog oboljenja. Ove preglede bi trebalo obavljati pre početka trenažnog procesa, kao i tokom perioda treniranja i takmičenja.",
publisher = "Univerzitet u Beogradu - Fakultet sporta i fizičkog vaspitanja, Beograd",
journal = "Fizička kultura",
title = "Athlete's heart, Corazon de deportista, Sportsko srce",
volume = "72",
number = "2",
pages = "139-147",
doi = "10.5937/fizkul1802139M"
}

Milutinović, K., Stojiljković, S., Ćuk, J., Lasica, R., Miosavljević, A., Cvetković, D., Trajković, A., Pešić, V., Arena, R.,& Popović, D.. (2018). Athlete's heart. in Fizička kultura
Univerzitet u Beogradu - Fakultet sporta i fizičkog vaspitanja, Beograd., 72(2), 139-147.
https://doi.org/10.5937/fizkul1802139M

Milutinović K, Stojiljković S, Ćuk J, Lasica R, Miosavljević A, Cvetković D, Trajković A, Pešić V, Arena R, Popović D. Athlete's heart. in Fizička kultura. 2018;72(2):139-147.
doi:10.5937/fizkul1802139M .

Milutinović, Katarina, Stojiljković, Stanimir, Ćuk, Jelena, Lasica, Ratko, Miosavljević, Andrej, Cvetković, Dimitrije, Trajković, Aleksandra, Pešić, Vesna, Arena, Ross, Popović, Dejana, "Athlete's heart" in Fizička kultura, 72, no. 2 (2018):139-147,
https://doi.org/10.5937/fizkul1802139M . .

TY  - JOUR
AU  - Ćuk, Jelena
AU  - Stojiljković, Stanimir
AU  - Milutinović, Katarina
AU  - Cvetković, Dimitrije
AU  - Pešić, Vesna
AU  - Arena, Ross
AU  - Popović, Dejana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3102
AB  - The athlete's heart is an exercise-induced cardiac remodeling phenomenon, which is individual and depends on the intensity, duration and frequency of training, as well as genetic factors. Cardiovascular screening prior to participation in sports activities, is a systematic practice of medical evaluation in the athlete population. The current US recommendations for the screening of cardiovascular abnormalities in high school and university athletes at all levels of performance were initially put forther by the American Heart Association in 2007. These recommendations consist of 12 points, factoring personal and family history data, as well as physical examination. On the other hand, European recommendations suggest the importance of non-invasive diagnostic methods, such as the 12-lead ECG, which should be carried out in combination with a history and physical examination. According to the European Association for Cardiovascular Imaging, standard echocardiography is the first line approach to differentiate an athlete's heart from pathological left ventricular hypertrophy. Updated 'Seattle criteria' from 2017. include criteria for assessing abnormalities in the electrocardiogram of athletes and their differentiation from the adaptive electrophysiological changes, which do not require further evaluation. Since sudden cardiac death during sport activities remains a major concern and, as such, it is imperative for the physician to diagnose unrecognized pathological conditions in athletes. Following current expert consensus recommendations on this topic helps to prevent untoward events during physical activity in those who are found to be at elevated risk.
AB  - Atletsko srce je fenomen remodelovanja srčanog mišića, koje je nastalo usled fizičke aktivnosti, a čiji stepen zavisi od intenziteta, trajanja, učestalosti treniranja, individualnih osobina i genetskih faktora. Aktuelne američke preporuke za skrining kardiovaskularnih abnormalnosti među sportistima srednjoškolcima i studentima svih nivoa utreniranosti, inicijalno su bile postavljene od strane Američkog udruženja kardiologa 2007. godine. Ove preporuke čini 12 tačaka i podrazumevaju podatke iz lične i porodične istorije bolesti, kao i fizičkog pregleda. S druge strane, evropske preporuke sugerišu na značaj neinvazivnih dijagnostičkih metoda, kao što je 12-kanalni EKG, čiji rezultati bi trebali biti razmatrani udruženo sa istorijom bolesti i fizičkim pregledom. Prema Evropskom udruženju za kardiovakularni imidžing, standardna ehokardiografija je prva dijagnostička metoda diferencijacije sportskog srca od patološke hipertrofije leve komore. Godine 2012, Američko udruženje za sportsku medicine je definisalo kriterijume, koji su osveženi 2017. godine, za utvrđivanje abnormalnosti u elektrokardiogramu sportista i njihovu diferencijaciju od adaptivnih elektrofizoloških promena, koje ne zahtevaju dalju evaluaciju. S obzirom na to da iznenadna srčana smrt u sportu zahteva veliku pažnju, neophodno je da lekari budu edukovani da dijagnostikuju neprepoznata patološka stanja kod sportista. Praćenje aktuelnih preporuka koje se bave ovim problemom doprinosi prevenciji neželjenih događaja u sportu i kod osoba koje su iz drugih razloga izložene velikim fizičkim naporima.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - The athlete's heart: Modern diagnostic approach
T1  - Sportsko srce - savremeni dijagnostički pristup
VL  - 68
IS  - 4
SP  - 900
EP  - 910
DO  - 10.5937/ArhFarm1804900C
ER  - 

@article{
author = "Ćuk, Jelena and Stojiljković, Stanimir and Milutinović, Katarina and Cvetković, Dimitrije and Pešić, Vesna and Arena, Ross and Popović, Dejana",
year = "2018",
abstract = "The athlete's heart is an exercise-induced cardiac remodeling phenomenon, which is individual and depends on the intensity, duration and frequency of training, as well as genetic factors. Cardiovascular screening prior to participation in sports activities, is a systematic practice of medical evaluation in the athlete population. The current US recommendations for the screening of cardiovascular abnormalities in high school and university athletes at all levels of performance were initially put forther by the American Heart Association in 2007. These recommendations consist of 12 points, factoring personal and family history data, as well as physical examination. On the other hand, European recommendations suggest the importance of non-invasive diagnostic methods, such as the 12-lead ECG, which should be carried out in combination with a history and physical examination. According to the European Association for Cardiovascular Imaging, standard echocardiography is the first line approach to differentiate an athlete's heart from pathological left ventricular hypertrophy. Updated 'Seattle criteria' from 2017. include criteria for assessing abnormalities in the electrocardiogram of athletes and their differentiation from the adaptive electrophysiological changes, which do not require further evaluation. Since sudden cardiac death during sport activities remains a major concern and, as such, it is imperative for the physician to diagnose unrecognized pathological conditions in athletes. Following current expert consensus recommendations on this topic helps to prevent untoward events during physical activity in those who are found to be at elevated risk., Atletsko srce je fenomen remodelovanja srčanog mišića, koje je nastalo usled fizičke aktivnosti, a čiji stepen zavisi od intenziteta, trajanja, učestalosti treniranja, individualnih osobina i genetskih faktora. Aktuelne američke preporuke za skrining kardiovaskularnih abnormalnosti među sportistima srednjoškolcima i studentima svih nivoa utreniranosti, inicijalno su bile postavljene od strane Američkog udruženja kardiologa 2007. godine. Ove preporuke čini 12 tačaka i podrazumevaju podatke iz lične i porodične istorije bolesti, kao i fizičkog pregleda. S druge strane, evropske preporuke sugerišu na značaj neinvazivnih dijagnostičkih metoda, kao što je 12-kanalni EKG, čiji rezultati bi trebali biti razmatrani udruženo sa istorijom bolesti i fizičkim pregledom. Prema Evropskom udruženju za kardiovakularni imidžing, standardna ehokardiografija je prva dijagnostička metoda diferencijacije sportskog srca od patološke hipertrofije leve komore. Godine 2012, Američko udruženje za sportsku medicine je definisalo kriterijume, koji su osveženi 2017. godine, za utvrđivanje abnormalnosti u elektrokardiogramu sportista i njihovu diferencijaciju od adaptivnih elektrofizoloških promena, koje ne zahtevaju dalju evaluaciju. S obzirom na to da iznenadna srčana smrt u sportu zahteva veliku pažnju, neophodno je da lekari budu edukovani da dijagnostikuju neprepoznata patološka stanja kod sportista. Praćenje aktuelnih preporuka koje se bave ovim problemom doprinosi prevenciji neželjenih događaja u sportu i kod osoba koje su iz drugih razloga izložene velikim fizičkim naporima.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "The athlete's heart: Modern diagnostic approach, Sportsko srce - savremeni dijagnostički pristup",
volume = "68",
number = "4",
pages = "900-910",
doi = "10.5937/ArhFarm1804900C"
}

Ćuk, J., Stojiljković, S., Milutinović, K., Cvetković, D., Pešić, V., Arena, R.,& Popović, D.. (2018). The athlete's heart: Modern diagnostic approach. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 68(4), 900-910.
https://doi.org/10.5937/ArhFarm1804900C

Ćuk J, Stojiljković S, Milutinović K, Cvetković D, Pešić V, Arena R, Popović D. The athlete's heart: Modern diagnostic approach. in Arhiv za farmaciju. 2018;68(4):900-910.
doi:10.5937/ArhFarm1804900C .

Ćuk, Jelena, Stojiljković, Stanimir, Milutinović, Katarina, Cvetković, Dimitrije, Pešić, Vesna, Arena, Ross, Popović, Dejana, "The athlete's heart: Modern diagnostic approach" in Arhiv za farmaciju, 68, no. 4 (2018):900-910,
https://doi.org/10.5937/ArhFarm1804900C . .

TY  - JOUR
AU  - Popović, Dejana
AU  - Damjanović, Svetozar S.
AU  - Plećaš-Solarović, Bosiljka
AU  - Pešić, Vesna
AU  - Stojiljković, Stanimir
AU  - Banović, Marko
AU  - Ristić, Arsen
AU  - Mantegazza, Valentina
AU  - Agostoni, Piergiuseppe
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2619
AB  - The usage of alcohol is widespread, but the effects of acute alcohol ingestion on exercise performance and the stress hormone axis are not fully elucidated.We studied 10 healthy white men, nonhabitual drinkers, by Doppler echocardiography at rest, spirometry, and maximal cardiopulmonary exercise test (CPET) in two visits (2-4 days in between), one after administration of 1.5g/kg ethanol (whisky) diluted at 15% in water, and the other after administration of an equivalent volume of water. Plasma levels of NT-pro-BNP, cortisol, and adrenocorticotropic hormone (ACTH) were also measured 10min before the test, at maximal effort and at the third minute of recovery. Ethanol concentration was measured from resting blood samples by gas chromatography and it increased from 0.00 +/- 0.00 to 1.25 +/- 0.54 parts per thousand (P lt 0.001). Basal echocardiographic and spirometric parameters were normal and remained so after acute alcohol intake, whereas ACTH, cortisol, and NT-pro-BNP nonsignificantly increased in all phases of the test. CPET data suggested a trend toward a slight reduction of exercise performance (peak VO2=3008 +/- 638 vs. 2900 +/- 543ml/min, ns; peak workload=269 +/- 53 vs. 249 +/- 40W, ns; test duration 13.7 +/- 2.2 vs. 13.3 +/- 1.7min, ns; VE/VCO2 22.1 +/- 1.4 vs. 23.3 +/- 2.9, ns). Ventilatory equivalent for carbon dioxide at rest was higher after alcohol intake (28 +/- 2.5 vs. 30.4 +/- 3.2, P=0.039) and maximal respiratory exchange ratio was lower after alcohol intake (1.17 +/- 0.02 vs. 1.14 +/- 0.04, P=0.04). In conclusion, we showed that acute alcohol intake in healthy white men is associated with a nonsignificant exercise performance reduction and stress hormone stimulation, with an unchanged exercise metabolism.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Journal of Cardiovascular Medicine
T1  - Exercise capacity is not impaired after acute alcohol ingestion: a pilot study
VL  - 17
IS  - 12
SP  - 896
EP  - 901
DO  - 10.2459/JCM.0000000000000151
ER  - 

@article{
author = "Popović, Dejana and Damjanović, Svetozar S. and Plećaš-Solarović, Bosiljka and Pešić, Vesna and Stojiljković, Stanimir and Banović, Marko and Ristić, Arsen and Mantegazza, Valentina and Agostoni, Piergiuseppe",
year = "2016",
abstract = "The usage of alcohol is widespread, but the effects of acute alcohol ingestion on exercise performance and the stress hormone axis are not fully elucidated.We studied 10 healthy white men, nonhabitual drinkers, by Doppler echocardiography at rest, spirometry, and maximal cardiopulmonary exercise test (CPET) in two visits (2-4 days in between), one after administration of 1.5g/kg ethanol (whisky) diluted at 15% in water, and the other after administration of an equivalent volume of water. Plasma levels of NT-pro-BNP, cortisol, and adrenocorticotropic hormone (ACTH) were also measured 10min before the test, at maximal effort and at the third minute of recovery. Ethanol concentration was measured from resting blood samples by gas chromatography and it increased from 0.00 +/- 0.00 to 1.25 +/- 0.54 parts per thousand (P lt 0.001). Basal echocardiographic and spirometric parameters were normal and remained so after acute alcohol intake, whereas ACTH, cortisol, and NT-pro-BNP nonsignificantly increased in all phases of the test. CPET data suggested a trend toward a slight reduction of exercise performance (peak VO2=3008 +/- 638 vs. 2900 +/- 543ml/min, ns; peak workload=269 +/- 53 vs. 249 +/- 40W, ns; test duration 13.7 +/- 2.2 vs. 13.3 +/- 1.7min, ns; VE/VCO2 22.1 +/- 1.4 vs. 23.3 +/- 2.9, ns). Ventilatory equivalent for carbon dioxide at rest was higher after alcohol intake (28 +/- 2.5 vs. 30.4 +/- 3.2, P=0.039) and maximal respiratory exchange ratio was lower after alcohol intake (1.17 +/- 0.02 vs. 1.14 +/- 0.04, P=0.04). In conclusion, we showed that acute alcohol intake in healthy white men is associated with a nonsignificant exercise performance reduction and stress hormone stimulation, with an unchanged exercise metabolism.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Journal of Cardiovascular Medicine",
title = "Exercise capacity is not impaired after acute alcohol ingestion: a pilot study",
volume = "17",
number = "12",
pages = "896-901",
doi = "10.2459/JCM.0000000000000151"
}

Popović, D., Damjanović, S. S., Plećaš-Solarović, B., Pešić, V., Stojiljković, S., Banović, M., Ristić, A., Mantegazza, V.,& Agostoni, P.. (2016). Exercise capacity is not impaired after acute alcohol ingestion: a pilot study. in Journal of Cardiovascular Medicine
Lippincott Williams & Wilkins, Philadelphia., 17(12), 896-901.
https://doi.org/10.2459/JCM.0000000000000151

Popović D, Damjanović SS, Plećaš-Solarović B, Pešić V, Stojiljković S, Banović M, Ristić A, Mantegazza V, Agostoni P. Exercise capacity is not impaired after acute alcohol ingestion: a pilot study. in Journal of Cardiovascular Medicine. 2016;17(12):896-901.
doi:10.2459/JCM.0000000000000151 .

Popović, Dejana, Damjanović, Svetozar S., Plećaš-Solarović, Bosiljka, Pešić, Vesna, Stojiljković, Stanimir, Banović, Marko, Ristić, Arsen, Mantegazza, Valentina, Agostoni, Piergiuseppe, "Exercise capacity is not impaired after acute alcohol ingestion: a pilot study" in Journal of Cardiovascular Medicine, 17, no. 12 (2016):896-901,
https://doi.org/10.2459/JCM.0000000000000151 . .

TY  - JOUR
AU  - Popović, Dejana
AU  - Popović, Bojana
AU  - Plećaš-Solarović, Bosiljka
AU  - Pešić, Vesna
AU  - Marković, Vidan
AU  - Stojiljković, Stanimir
AU  - Vukcević, Vladan
AU  - Petrović, Ivana
AU  - Banović, Marko
AU  - Petrović, Milan
AU  - Vujisić-Tesić, Bosiljka
AU  - Ostojić, Miodrag
AU  - Ristić, Arsen
AU  - Damjanović, Svetozar S.
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1857
AB  - Brain natriuretic peptide (NT-pro-BNP) was implicated in the regulation of hypothalamic-pituitary-adrenocortical (HPA) responses to psychological stressors. However, HPA axis activation in different physical stress models and its interface with NT-pro-BNP in the prediction of cardiopulmonary performance is unclear. Cardiopulmonary test on a treadmill was used to assess cardiopulmonary parameters in 16 elite male wrestlers (W), 21 water polo player (WP) and 20 sedentary age-matched subjects
PB  - Elsevier Science Inc, New York
T2  - Peptides
T1  - The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress
VL  - 47
SP  - 85
EP  - 93
DO  - 10.1016/j.peptides.2013.07.009
ER  - 

@article{
author = "Popović, Dejana and Popović, Bojana and Plećaš-Solarović, Bosiljka and Pešić, Vesna and Marković, Vidan and Stojiljković, Stanimir and Vukcević, Vladan and Petrović, Ivana and Banović, Marko and Petrović, Milan and Vujisić-Tesić, Bosiljka and Ostojić, Miodrag and Ristić, Arsen and Damjanović, Svetozar S.",
year = "2013",
abstract = "Brain natriuretic peptide (NT-pro-BNP) was implicated in the regulation of hypothalamic-pituitary-adrenocortical (HPA) responses to psychological stressors. However, HPA axis activation in different physical stress models and its interface with NT-pro-BNP in the prediction of cardiopulmonary performance is unclear. Cardiopulmonary test on a treadmill was used to assess cardiopulmonary parameters in 16 elite male wrestlers (W), 21 water polo player (WP) and 20 sedentary age-matched subjects",
publisher = "Elsevier Science Inc, New York",
journal = "Peptides",
title = "The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress",
volume = "47",
pages = "85-93",
doi = "10.1016/j.peptides.2013.07.009"
}

Popović, D., Popović, B., Plećaš-Solarović, B., Pešić, V., Marković, V., Stojiljković, S., Vukcević, V., Petrović, I., Banović, M., Petrović, M., Vujisić-Tesić, B., Ostojić, M., Ristić, A.,& Damjanović, S. S.. (2013). The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress. in Peptides
Elsevier Science Inc, New York., 47, 85-93.
https://doi.org/10.1016/j.peptides.2013.07.009

Popović D, Popović B, Plećaš-Solarović B, Pešić V, Marković V, Stojiljković S, Vukcević V, Petrović I, Banović M, Petrović M, Vujisić-Tesić B, Ostojić M, Ristić A, Damjanović SS. The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress. in Peptides. 2013;47:85-93.
doi:10.1016/j.peptides.2013.07.009 .

Popović, Dejana, Popović, Bojana, Plećaš-Solarović, Bosiljka, Pešić, Vesna, Marković, Vidan, Stojiljković, Stanimir, Vukcević, Vladan, Petrović, Ivana, Banović, Marko, Petrović, Milan, Vujisić-Tesić, Bosiljka, Ostojić, Miodrag, Ristić, Arsen, Damjanović, Svetozar S., "The interface of hypothalamic-pituitary-adrenocortical axis and circulating brain natriuretic peptide in prediction of cardiopulmonary performance during physical stress" in Peptides, 47 (2013):85-93,
https://doi.org/10.1016/j.peptides.2013.07.009 . .