Nikolić, Dragica

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  • Nikolić, Dragica (7)
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Author's Bibliography

Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina)

Šljivić Husejnović, Maida; Janković, Saša; Nikolić, Dragica; Antonijević, Biljana

(Sciendo, 2021)

TY  - JOUR
AU  - Šljivić Husejnović, Maida
AU  - Janković, Saša
AU  - Nikolić, Dragica
AU  - Antonijević, Biljana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4049
AB  - The aim of this study was to assess the risk of human exposure to lead (Pb), cadmium (Cd), and mercury (Hg) through agricultural soil by considering both uncertainty and variability in key exposure parameters. For this reason we collected soil samples from 29 locations in the Tuzla Canton (Bosnia and Herzegovina) and measured their metal levels with inductively coupled plasma atomic emission or absorption spectrometry (ICP-AES and ICP-AAS, respectively). The levels of Pb ranged from 13.33 to 1692.33 mg/kg, of Cd from 0.05 to 3.67 mg/kg, and of Hg from 0.02 to 2.73 mg/kg. To estimate cancer and non-cancer risks we used deterministic and semi-probabilistic methods. Lead was found to involve higher health risk than the other two heavy metals. Its hazard index (HI) decreased between population groups (children>women>men) and exposure routes (ingestion>skin contact>inhalation). Our Monte Carlo simulations indicated that Pb HIs for both adult populations had a 0.6 % probability to exceed the threshold value of 1, while in children this probability was 14.2 %. Cd and Hg showed no probability to exceed the threshold in any scenario. Our simulation results raise concern about possible adverse health effects of heavy metals from soil, especially in children. It is very important to continue monitoring environmental pollution and assess human health risk, not only with respect to soil, but also with other important environmental compartments, such as air and water.
AB  - Cilj ovog istraživanja bio je procijeniti izloženost ljudi olovu (Pb), kadmiju (Cd) i živi (Hg) iz poljoprivrednog tla,
uzimajući u obzir pridružene nesigurnosti i varijabilnosti u ključnim parametrima izloženosti. Primjenom metoda induktivno
spregnute plazme i atomske emisijske ili apsorpcijske spektrometrije (ICP-AES i AAS) određena je koncentracija metala
u uzorcima poljoprivrednoga tla prikupljenog s 29 lokacija u Tuzlanskom kantonu (Bosna i Hercegovina). Koncentracije
Pb kretale su se u rasponu od 13,33 do 1692,33 mg/kg, Cd od 0,05 do 3,67 mg/kg i Hg od 0,02 do 2,73 mg/kg. Za procjenu
kancerogenog i nekancerogenog rizika koristili smo se determinističkim i semiprobabilističkim pristupom u procjeni
rizika. Utvrđeno je da Pb doprinosi povećanom zdravstvenom riziku više nego druga dva teška metala. Indeks opasnosti
(eng. hazard index ‒ HI) smanjivao se među populacijskim skupinama (djeca > žene > muškarci) i putevima izloženosti
(ingestija > dermalni kontakt > inhalacija). Naše Monte Carlo simulacije pokazale su da HI za Pb uključujuči obje
populacije odraslih imaju 0,6 % vjerojatnosti da će prijeći vrijednost praga od 1, dok je u djece ta vjerojatnost bila 14,2 %.
Vjerojatnost da će premašiti prag u bilo kom scenariju nisu pokazali Cd i Hg. Rezultati naših simulacija izazivaju zabrinutost
zbog mogućih štetnih učinaka teških metala iz tla, posebice u djece. Vrlo je važno nastaviti pratiti onečišćenje okoliša i
procijeniti rizik za zdravlje ljudi, ne samo putem tla, već i putem drugih značajnih dijelova okoliša, poput zraka i vode.
PB  - Sciendo
T2  - Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
T1  - Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina)
T1  - Procjena zdravstvenoga rizika nakon istovremenog izlaganja olovu, kadmiju i živi iz poljoprivrednoga tla s područja
Tuzlanskoga kantona (Bosna i Hercegovina)
VL  - 72
IS  - 4
SP  - 268
EP  - 279
DO  - 10.2478/aiht-2021-72-3533
ER  - 
@article{
author = "Šljivić Husejnović, Maida and Janković, Saša and Nikolić, Dragica and Antonijević, Biljana",
year = "2021",
abstract = "The aim of this study was to assess the risk of human exposure to lead (Pb), cadmium (Cd), and mercury (Hg) through agricultural soil by considering both uncertainty and variability in key exposure parameters. For this reason we collected soil samples from 29 locations in the Tuzla Canton (Bosnia and Herzegovina) and measured their metal levels with inductively coupled plasma atomic emission or absorption spectrometry (ICP-AES and ICP-AAS, respectively). The levels of Pb ranged from 13.33 to 1692.33 mg/kg, of Cd from 0.05 to 3.67 mg/kg, and of Hg from 0.02 to 2.73 mg/kg. To estimate cancer and non-cancer risks we used deterministic and semi-probabilistic methods. Lead was found to involve higher health risk than the other two heavy metals. Its hazard index (HI) decreased between population groups (children>women>men) and exposure routes (ingestion>skin contact>inhalation). Our Monte Carlo simulations indicated that Pb HIs for both adult populations had a 0.6 % probability to exceed the threshold value of 1, while in children this probability was 14.2 %. Cd and Hg showed no probability to exceed the threshold in any scenario. Our simulation results raise concern about possible adverse health effects of heavy metals from soil, especially in children. It is very important to continue monitoring environmental pollution and assess human health risk, not only with respect to soil, but also with other important environmental compartments, such as air and water., Cilj ovog istraživanja bio je procijeniti izloženost ljudi olovu (Pb), kadmiju (Cd) i živi (Hg) iz poljoprivrednog tla,
uzimajući u obzir pridružene nesigurnosti i varijabilnosti u ključnim parametrima izloženosti. Primjenom metoda induktivno
spregnute plazme i atomske emisijske ili apsorpcijske spektrometrije (ICP-AES i AAS) određena je koncentracija metala
u uzorcima poljoprivrednoga tla prikupljenog s 29 lokacija u Tuzlanskom kantonu (Bosna i Hercegovina). Koncentracije
Pb kretale su se u rasponu od 13,33 do 1692,33 mg/kg, Cd od 0,05 do 3,67 mg/kg i Hg od 0,02 do 2,73 mg/kg. Za procjenu
kancerogenog i nekancerogenog rizika koristili smo se determinističkim i semiprobabilističkim pristupom u procjeni
rizika. Utvrđeno je da Pb doprinosi povećanom zdravstvenom riziku više nego druga dva teška metala. Indeks opasnosti
(eng. hazard index ‒ HI) smanjivao se među populacijskim skupinama (djeca > žene > muškarci) i putevima izloženosti
(ingestija > dermalni kontakt > inhalacija). Naše Monte Carlo simulacije pokazale su da HI za Pb uključujuči obje
populacije odraslih imaju 0,6 % vjerojatnosti da će prijeći vrijednost praga od 1, dok je u djece ta vjerojatnost bila 14,2 %.
Vjerojatnost da će premašiti prag u bilo kom scenariju nisu pokazali Cd i Hg. Rezultati naših simulacija izazivaju zabrinutost
zbog mogućih štetnih učinaka teških metala iz tla, posebice u djece. Vrlo je važno nastaviti pratiti onečišćenje okoliša i
procijeniti rizik za zdravlje ljudi, ne samo putem tla, već i putem drugih značajnih dijelova okoliša, poput zraka i vode.",
publisher = "Sciendo",
journal = "Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology",
title = "Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina), Procjena zdravstvenoga rizika nakon istovremenog izlaganja olovu, kadmiju i živi iz poljoprivrednoga tla s područja
Tuzlanskoga kantona (Bosna i Hercegovina)",
volume = "72",
number = "4",
pages = "268-279",
doi = "10.2478/aiht-2021-72-3533"
}
Šljivić Husejnović, M., Janković, S., Nikolić, D.,& Antonijević, B.. (2021). Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina). in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
Sciendo., 72(4), 268-279.
https://doi.org/10.2478/aiht-2021-72-3533
Šljivić Husejnović M, Janković S, Nikolić D, Antonijević B. Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina). in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology. 2021;72(4):268-279.
doi:10.2478/aiht-2021-72-3533 .
Šljivić Husejnović, Maida, Janković, Saša, Nikolić, Dragica, Antonijević, Biljana, "Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina)" in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology, 72, no. 4 (2021):268-279,
https://doi.org/10.2478/aiht-2021-72-3533 . .
9
7

Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level

Bulat, Zorica; Ćurčić, Marijana; Antunović, Marko; Vučinić, Slavica; Buha-Đorđević, Aleksandra; Janković, Saša; Nikolić, Dragica; Matović, Vesna; Đukić-Ćosić, Danijela; Antonijević, Evica; Baralić, Katarina; Antonijević, Biljana

(Elsevier Ireland Ltd, Clare, 2017)

TY  - CONF
AU  - Bulat, Zorica
AU  - Ćurčić, Marijana
AU  - Antunović, Marko
AU  - Vučinić, Slavica
AU  - Buha-Đorđević, Aleksandra
AU  - Janković, Saša
AU  - Nikolić, Dragica
AU  - Matović, Vesna
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Baralić, Katarina
AU  - Antonijević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2887
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level
VL  - 280
IS  - Supplement 1
SP  - S152
EP  - S152
DO  - 10.1016/j.toxlet.2017.07.426
ER  - 
@conference{
author = "Bulat, Zorica and Ćurčić, Marijana and Antunović, Marko and Vučinić, Slavica and Buha-Đorđević, Aleksandra and Janković, Saša and Nikolić, Dragica and Matović, Vesna and Đukić-Ćosić, Danijela and Antonijević, Evica and Baralić, Katarina and Antonijević, Biljana",
year = "2017",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level",
volume = "280",
number = "Supplement 1",
pages = "S152-S152",
doi = "10.1016/j.toxlet.2017.07.426"
}
Bulat, Z., Ćurčić, M., Antunović, M., Vučinić, S., Buha-Đorđević, A., Janković, S., Nikolić, D., Matović, V., Đukić-Ćosić, D., Antonijević, E., Baralić, K.,& Antonijević, B.. (2017). Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 280(Supplement 1), S152-S152.
https://doi.org/10.1016/j.toxlet.2017.07.426
Bulat Z, Ćurčić M, Antunović M, Vučinić S, Buha-Đorđević A, Janković S, Nikolić D, Matović V, Đukić-Ćosić D, Antonijević E, Baralić K, Antonijević B. Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level. in Toxicology Letters. 2017;280(Supplement 1):S152-S152.
doi:10.1016/j.toxlet.2017.07.426 .
Bulat, Zorica, Ćurčić, Marijana, Antunović, Marko, Vučinić, Slavica, Buha-Đorđević, Aleksandra, Janković, Saša, Nikolić, Dragica, Matović, Vesna, Đukić-Ćosić, Danijela, Antonijević, Evica, Baralić, Katarina, Antonijević, Biljana, "Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level" in Toxicology Letters, 280, no. Supplement 1 (2017):S152-S152,
https://doi.org/10.1016/j.toxlet.2017.07.426 . .

Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market

Janković, Saša; Đinović-Stojanović, Jasna; Stefanović, Srđan; Radičević, Tatjana; Ćurčić, Marijana; Nikolić, Dragica; Spirić, Danka

(Elsevier Science BV, Amsterdam, 2015)

TY  - CONF
AU  - Janković, Saša
AU  - Đinović-Stojanović, Jasna
AU  - Stefanović, Srđan
AU  - Radičević, Tatjana
AU  - Ćurčić, Marijana
AU  - Nikolić, Dragica
AU  - Spirić, Danka
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2518
AB  - Mackerel is rich in omega-3 fatty acids, but this fish may be contaminated with environmental pollutants. The aim of this study was to evaluate concentrations of non-dioxin like polychlorinated biphenyls (ndl-PCBs) in 160 samples of mackerel available on the Serbian market. Average and maximum ndl-PCB concentrations were 7.9 ng/g and 74 ng/g, respectively. A higher average level of ndl-PCBs was found in mackerel from Spain, but this was still three times lower than the permitted level. We conclude that levels of ndl-PCBs in mackerel available on the Serbian market are acceptable.
PB  - Elsevier Science BV, Amsterdam
C3  - 58th International Meat Industry Conference (MEATCON2015)
T1  - Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market
VL  - 5
SP  - 113
EP  - 116
DO  - 10.1016/j.profoo.2015.09.031
ER  - 
@conference{
author = "Janković, Saša and Đinović-Stojanović, Jasna and Stefanović, Srđan and Radičević, Tatjana and Ćurčić, Marijana and Nikolić, Dragica and Spirić, Danka",
year = "2015",
abstract = "Mackerel is rich in omega-3 fatty acids, but this fish may be contaminated with environmental pollutants. The aim of this study was to evaluate concentrations of non-dioxin like polychlorinated biphenyls (ndl-PCBs) in 160 samples of mackerel available on the Serbian market. Average and maximum ndl-PCB concentrations were 7.9 ng/g and 74 ng/g, respectively. A higher average level of ndl-PCBs was found in mackerel from Spain, but this was still three times lower than the permitted level. We conclude that levels of ndl-PCBs in mackerel available on the Serbian market are acceptable.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "58th International Meat Industry Conference (MEATCON2015)",
title = "Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market",
volume = "5",
pages = "113-116",
doi = "10.1016/j.profoo.2015.09.031"
}
Janković, S., Đinović-Stojanović, J., Stefanović, S., Radičević, T., Ćurčić, M., Nikolić, D.,& Spirić, D.. (2015). Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market. in 58th International Meat Industry Conference (MEATCON2015)
Elsevier Science BV, Amsterdam., 5, 113-116.
https://doi.org/10.1016/j.profoo.2015.09.031
Janković S, Đinović-Stojanović J, Stefanović S, Radičević T, Ćurčić M, Nikolić D, Spirić D. Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market. in 58th International Meat Industry Conference (MEATCON2015). 2015;5:113-116.
doi:10.1016/j.profoo.2015.09.031 .
Janković, Saša, Đinović-Stojanović, Jasna, Stefanović, Srđan, Radičević, Tatjana, Ćurčić, Marijana, Nikolić, Dragica, Spirić, Danka, "Non-dioxin like polychlorinated biphenyls in mackerel (Scomber scombrus) available on the Serbian market" in 58th International Meat Industry Conference (MEATCON2015), 5 (2015):113-116,
https://doi.org/10.1016/j.profoo.2015.09.031 . .
1
1

Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats

Ćurčić, Marijana; Janković, Saša; Nikolić, Dragica; Bulat, Zorica; Durgo, Ksenija; Vučinić, Slavica; Antonijević, Biljana

(Elsevier Ireland Ltd, Clare, 2015)

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Janković, Saša
AU  - Nikolić, Dragica
AU  - Bulat, Zorica
AU  - Durgo, Ksenija
AU  - Vučinić, Slavica
AU  - Antonijević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2373
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats
VL  - 238
IS  - 2, Supplement
SP  - S295
EP  - S295
DO  - 10.1016/j.toxlet.2015.08.847
ER  - 
@conference{
author = "Ćurčić, Marijana and Janković, Saša and Nikolić, Dragica and Bulat, Zorica and Durgo, Ksenija and Vučinić, Slavica and Antonijević, Biljana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats",
volume = "238",
number = "2, Supplement",
pages = "S295-S295",
doi = "10.1016/j.toxlet.2015.08.847"
}
Ćurčić, M., Janković, S., Nikolić, D., Bulat, Z., Durgo, K., Vučinić, S.,& Antonijević, B.. (2015). Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S295-S295.
https://doi.org/10.1016/j.toxlet.2015.08.847
Ćurčić M, Janković S, Nikolić D, Bulat Z, Durgo K, Vučinić S, Antonijević B. Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats. in Toxicology Letters. 2015;238(2, Supplement):S295-S295.
doi:10.1016/j.toxlet.2015.08.847 .
Ćurčić, Marijana, Janković, Saša, Nikolić, Dragica, Bulat, Zorica, Durgo, Ksenija, Vučinić, Slavica, Antonijević, Biljana, "Benchmark dose for decabrominated diphenyl ether and cadmium effect on Cu increase in liver of Wistar rats" in Toxicology Letters, 238, no. 2, Supplement (2015):S295-S295,
https://doi.org/10.1016/j.toxlet.2015.08.847 . .

Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats

Buha, Aleksandra; Milovanović, Vesna; Nikolić, Dragica; Đukić-Ćosić, Danijela; Vukomanović, Predrag; Matović, Vesna

(Elsevier Ireland Ltd, Clare, 2015)

TY  - CONF
AU  - Buha, Aleksandra
AU  - Milovanović, Vesna
AU  - Nikolić, Dragica
AU  - Đukić-Ćosić, Danijela
AU  - Vukomanović, Predrag
AU  - Matović, Vesna
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2368
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats
VL  - 238
IS  - 2, Supplement
SP  - S123
EP  - S124
DO  - 10.1016/j.toxlet.2015.08.393
ER  - 
@conference{
author = "Buha, Aleksandra and Milovanović, Vesna and Nikolić, Dragica and Đukić-Ćosić, Danijela and Vukomanović, Predrag and Matović, Vesna",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats",
volume = "238",
number = "2, Supplement",
pages = "S123-S124",
doi = "10.1016/j.toxlet.2015.08.393"
}
Buha, A., Milovanović, V., Nikolić, D., Đukić-Ćosić, D., Vukomanović, P.,& Matović, V.. (2015). Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S123-S124.
https://doi.org/10.1016/j.toxlet.2015.08.393
Buha A, Milovanović V, Nikolić D, Đukić-Ćosić D, Vukomanović P, Matović V. Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats. in Toxicology Letters. 2015;238(2, Supplement):S123-S124.
doi:10.1016/j.toxlet.2015.08.393 .
Buha, Aleksandra, Milovanović, Vesna, Nikolić, Dragica, Đukić-Ćosić, Danijela, Vukomanović, Predrag, Matović, Vesna, "Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats" in Toxicology Letters, 238, no. 2, Supplement (2015):S123-S124,
https://doi.org/10.1016/j.toxlet.2015.08.393 . .

The use of @risk software for risk assessment of mercury intake via marine food among Serbian population

Buha, Aleksandra; Filipović, Angelina; Dumanović, Jelena; Antonijević, Evica; Ćurčić, Marijana; Janković, Saša; Nikolić, Dragica; Antonijević, Biljana

(Elsevier Ireland Ltd, Clare, 2013)

TY  - CONF
AU  - Buha, Aleksandra
AU  - Filipović, Angelina
AU  - Dumanović, Jelena
AU  - Antonijević, Evica
AU  - Ćurčić, Marijana
AU  - Janković, Saša
AU  - Nikolić, Dragica
AU  - Antonijević, Biljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1856
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - The use of @risk software for risk assessment of mercury intake via marine food among Serbian population
VL  - 221
IS  - Supplement
SP  - S222
EP  - S223
DO  - 10.1016/j.toxlet.2013.05.533
ER  - 
@conference{
author = "Buha, Aleksandra and Filipović, Angelina and Dumanović, Jelena and Antonijević, Evica and Ćurčić, Marijana and Janković, Saša and Nikolić, Dragica and Antonijević, Biljana",
year = "2013",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The use of @risk software for risk assessment of mercury intake via marine food among Serbian population",
volume = "221",
number = "Supplement",
pages = "S222-S223",
doi = "10.1016/j.toxlet.2013.05.533"
}
Buha, A., Filipović, A., Dumanović, J., Antonijević, E., Ćurčić, M., Janković, S., Nikolić, D.,& Antonijević, B.. (2013). The use of @risk software for risk assessment of mercury intake via marine food among Serbian population. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 221(Supplement), S222-S223.
https://doi.org/10.1016/j.toxlet.2013.05.533
Buha A, Filipović A, Dumanović J, Antonijević E, Ćurčić M, Janković S, Nikolić D, Antonijević B. The use of @risk software for risk assessment of mercury intake via marine food among Serbian population. in Toxicology Letters. 2013;221(Supplement):S222-S223.
doi:10.1016/j.toxlet.2013.05.533 .
Buha, Aleksandra, Filipović, Angelina, Dumanović, Jelena, Antonijević, Evica, Ćurčić, Marijana, Janković, Saša, Nikolić, Dragica, Antonijević, Biljana, "The use of @risk software for risk assessment of mercury intake via marine food among Serbian population" in Toxicology Letters, 221, no. Supplement (2013):S222-S223,
https://doi.org/10.1016/j.toxlet.2013.05.533 . .

Assessment of mercury intake associated with fish consumption in Serbia

Janković, Saša; Antonijević, Biljana; Ćurčić, Marijana; Radičević, Tatjana; Stefanović, Srđan; Nikolić, Dragica; Ćupić, Vitomir

(Institut za higijenu i tehnologiju mesa, Beograd, 2012)

TY  - JOUR
AU  - Janković, Saša
AU  - Antonijević, Biljana
AU  - Ćurčić, Marijana
AU  - Radičević, Tatjana
AU  - Stefanović, Srđan
AU  - Nikolić, Dragica
AU  - Ćupić, Vitomir
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1790
AB  - Nutritional benefits of fish can be attributed primarily to the content of high-quality proteins, vitamins, elements and omega-3 polyunsaturated fatty acids. On the other hand, fish and fishery products are susceptible to contamination by chemicals that have been recognized as ubiquitous environmental pollutants such as toxic elements and polychlorinated organic compounds. Fish consumption could be therefore considered as one of the major sources of human exposure to all above-mentioned environmental contaminants. This paper is focused on mercury (Hg) that enters the environment by both, natural means (such as volcanic activity, erosions and weathering, factors which contribute to the presence of Hg in water, soil and the atmosphere) and human activities - mining, fossil fuels combustion, industrial emissions, direct application of fertilizers and fungicides as well as disposal of solid waste. Total concentrations of Hg were measured in fish muscle and canned fish products available on Serbian market. Total of 651 samples were analyzed: 350 samples of marine fish (hake, mackerel, sprat, scorpanea, gilthead, salmon), 34 samples of freshwater fish (trout and carp) and 267 samples of canned fish products (tuna and sardines). Data were collected during 2011. For the purpose of intake assessment, we used the data obtained from the GEMS/Food Consumption Cluster Diets database. According to this source, estimated average weekly consumption of marine fish is 106.4 g/week, while freshwater fish and canned fish contribute to the consumption with 29.4 g and 18.2 g/week respectively. Mercury concentrations in marine fish were in the range of 0.005-0.208 μgg-1 (mean 0.040 μgg-1); in freshwater fish 0.005- 0.099 μgg-1 (mean 0.020 μgg-1) and in canned products they were in the range of 0.005-0.642 μgg-1 (mean 0.064 μgg-1). All analyzed samples contained mercury below the maximum level laid down by the European Union and Serbian regulation. The estimated weekly intake for total mercury, based on mean mercury value in fish and average body mass of 70 kg, was 0.095 μg/kg b.w./week. Based on FAO/WHO recommended safe limit and on obtained results, we can conclude that the intake of mercury in the case of consuming fish and canned fish products is lower than the safe limit.
AB  - Nutritivna korist od konzumacije ribe ogleda se, pre svega u sadržaju visoko vrednih proteina, vitamina, makro i mikroelemenata i omega-3 polinezasićenih masnih kiselina. Sa druge strane, riba i proizvodi od ribe su u značajnoj meri podložni hemijskoj kontaminaciji ubikvitarnim zagađivačima kao što su teški metal i polihlorovana organska jedinjenja. Zbog svega ovoga, konzumacija ribe se smatra jednim od najznačajnijih izvora izloženosti navedenim kontaminentima. U radu je ispitivana kontaminacija živom koja se u spoljašnjoj sredini može naći kao posledica prirodnih procesa (vulkanska aktivnost, erozija tla i klimatska dešavanja koja doprinose prisustvu žive u vodi, zemljištu i atmosferi), kao i aktivnosti čoveka - eksploatacija ruda, sagorevanje fosilnih goriva, emisija industrijskih gasova, direktna primena veštačkih đubriva i fungicida, kao i neadekvatno odlaganje čvrstog otpada. Sadržaj ukupne žive je određivan u svežoj i konzervisanoj ribi sa srpskog tržišta. Ispitan je 651 uzorak: 350 uzoraka morske ribe (oslić, skuša, sardela, škarpina, orada i losos), 34 uzorka slatkovodne ribe (šaran i pastrmka) i 267 uzoraka konzervisane ribe (tuna i sardela). Svi uzorci su analizirani tokom 2011. godine. Za procenu unosa korišćeni su podaci iz 'GEMS/Food Consumption Cluster Diets database'. Prema ovom izvoru, procenjena prosečna nedeljna konzumacija morske ribe iznosi 106,4 g, slatkovodne 29,4 g dok je ova vrednost za konzervisane proizvode od ribe 18,2 g. Sardžaj žive u morskoj ribi se kretao u opsegu od 0,005 do 0,208 μgg-1 (srednja vrednost 0,040 μgg-1); u slatkovodnoj ribi 0,005-0,099 μgg-1 (srednja vrednost 0,020 μgg-1), dok se u konzervisanim ribljim proizvodima sadržaj žive kretao od 0,005 do 0,642 μgg-1 (srednja vrednost 0,064 μgg-1). Nivo žive u svim ispitanim uzorcima je bio ispod maksimalno dozvoljenih vrednosti propisanih relevantnom legislativom EU kao i domaćim propisima. Procenjeni nedeljni unos žive baziran na srednjoj vrednosti žive u konzumiranoj ribi i prosečnoj telesnoj težini od 70 kg, bio je 0,095 μg/kg telesne mase nedeljno. Na osnovu preporuka FAO/WHO i dobijenih rezultata, može se zaključiti da je unos žive pri konzumaciji morske i slatkovodne ribe i konzervisanih ribljih proizvoda, niži od preporučenih graničnih vrednosti.
PB  - Institut za higijenu i tehnologiju mesa, Beograd
T2  - Tehnologija mesa
T1  - Assessment of mercury intake associated with fish consumption in Serbia
T1  - Procena unosa žive kroz konzumaciju ribe u Srbiji
VL  - 53
IS  - 1
SP  - 56
EP  - 61
DO  - 10.5937/tehmesa1201056J
ER  - 
@article{
author = "Janković, Saša and Antonijević, Biljana and Ćurčić, Marijana and Radičević, Tatjana and Stefanović, Srđan and Nikolić, Dragica and Ćupić, Vitomir",
year = "2012",
abstract = "Nutritional benefits of fish can be attributed primarily to the content of high-quality proteins, vitamins, elements and omega-3 polyunsaturated fatty acids. On the other hand, fish and fishery products are susceptible to contamination by chemicals that have been recognized as ubiquitous environmental pollutants such as toxic elements and polychlorinated organic compounds. Fish consumption could be therefore considered as one of the major sources of human exposure to all above-mentioned environmental contaminants. This paper is focused on mercury (Hg) that enters the environment by both, natural means (such as volcanic activity, erosions and weathering, factors which contribute to the presence of Hg in water, soil and the atmosphere) and human activities - mining, fossil fuels combustion, industrial emissions, direct application of fertilizers and fungicides as well as disposal of solid waste. Total concentrations of Hg were measured in fish muscle and canned fish products available on Serbian market. Total of 651 samples were analyzed: 350 samples of marine fish (hake, mackerel, sprat, scorpanea, gilthead, salmon), 34 samples of freshwater fish (trout and carp) and 267 samples of canned fish products (tuna and sardines). Data were collected during 2011. For the purpose of intake assessment, we used the data obtained from the GEMS/Food Consumption Cluster Diets database. According to this source, estimated average weekly consumption of marine fish is 106.4 g/week, while freshwater fish and canned fish contribute to the consumption with 29.4 g and 18.2 g/week respectively. Mercury concentrations in marine fish were in the range of 0.005-0.208 μgg-1 (mean 0.040 μgg-1); in freshwater fish 0.005- 0.099 μgg-1 (mean 0.020 μgg-1) and in canned products they were in the range of 0.005-0.642 μgg-1 (mean 0.064 μgg-1). All analyzed samples contained mercury below the maximum level laid down by the European Union and Serbian regulation. The estimated weekly intake for total mercury, based on mean mercury value in fish and average body mass of 70 kg, was 0.095 μg/kg b.w./week. Based on FAO/WHO recommended safe limit and on obtained results, we can conclude that the intake of mercury in the case of consuming fish and canned fish products is lower than the safe limit., Nutritivna korist od konzumacije ribe ogleda se, pre svega u sadržaju visoko vrednih proteina, vitamina, makro i mikroelemenata i omega-3 polinezasićenih masnih kiselina. Sa druge strane, riba i proizvodi od ribe su u značajnoj meri podložni hemijskoj kontaminaciji ubikvitarnim zagađivačima kao što su teški metal i polihlorovana organska jedinjenja. Zbog svega ovoga, konzumacija ribe se smatra jednim od najznačajnijih izvora izloženosti navedenim kontaminentima. U radu je ispitivana kontaminacija živom koja se u spoljašnjoj sredini može naći kao posledica prirodnih procesa (vulkanska aktivnost, erozija tla i klimatska dešavanja koja doprinose prisustvu žive u vodi, zemljištu i atmosferi), kao i aktivnosti čoveka - eksploatacija ruda, sagorevanje fosilnih goriva, emisija industrijskih gasova, direktna primena veštačkih đubriva i fungicida, kao i neadekvatno odlaganje čvrstog otpada. Sadržaj ukupne žive je određivan u svežoj i konzervisanoj ribi sa srpskog tržišta. Ispitan je 651 uzorak: 350 uzoraka morske ribe (oslić, skuša, sardela, škarpina, orada i losos), 34 uzorka slatkovodne ribe (šaran i pastrmka) i 267 uzoraka konzervisane ribe (tuna i sardela). Svi uzorci su analizirani tokom 2011. godine. Za procenu unosa korišćeni su podaci iz 'GEMS/Food Consumption Cluster Diets database'. Prema ovom izvoru, procenjena prosečna nedeljna konzumacija morske ribe iznosi 106,4 g, slatkovodne 29,4 g dok je ova vrednost za konzervisane proizvode od ribe 18,2 g. Sardžaj žive u morskoj ribi se kretao u opsegu od 0,005 do 0,208 μgg-1 (srednja vrednost 0,040 μgg-1); u slatkovodnoj ribi 0,005-0,099 μgg-1 (srednja vrednost 0,020 μgg-1), dok se u konzervisanim ribljim proizvodima sadržaj žive kretao od 0,005 do 0,642 μgg-1 (srednja vrednost 0,064 μgg-1). Nivo žive u svim ispitanim uzorcima je bio ispod maksimalno dozvoljenih vrednosti propisanih relevantnom legislativom EU kao i domaćim propisima. Procenjeni nedeljni unos žive baziran na srednjoj vrednosti žive u konzumiranoj ribi i prosečnoj telesnoj težini od 70 kg, bio je 0,095 μg/kg telesne mase nedeljno. Na osnovu preporuka FAO/WHO i dobijenih rezultata, može se zaključiti da je unos žive pri konzumaciji morske i slatkovodne ribe i konzervisanih ribljih proizvoda, niži od preporučenih graničnih vrednosti.",
publisher = "Institut za higijenu i tehnologiju mesa, Beograd",
journal = "Tehnologija mesa",
title = "Assessment of mercury intake associated with fish consumption in Serbia, Procena unosa žive kroz konzumaciju ribe u Srbiji",
volume = "53",
number = "1",
pages = "56-61",
doi = "10.5937/tehmesa1201056J"
}
Janković, S., Antonijević, B., Ćurčić, M., Radičević, T., Stefanović, S., Nikolić, D.,& Ćupić, V.. (2012). Assessment of mercury intake associated with fish consumption in Serbia. in Tehnologija mesa
Institut za higijenu i tehnologiju mesa, Beograd., 53(1), 56-61.
https://doi.org/10.5937/tehmesa1201056J
Janković S, Antonijević B, Ćurčić M, Radičević T, Stefanović S, Nikolić D, Ćupić V. Assessment of mercury intake associated with fish consumption in Serbia. in Tehnologija mesa. 2012;53(1):56-61.
doi:10.5937/tehmesa1201056J .
Janković, Saša, Antonijević, Biljana, Ćurčić, Marijana, Radičević, Tatjana, Stefanović, Srđan, Nikolić, Dragica, Ćupić, Vitomir, "Assessment of mercury intake associated with fish consumption in Serbia" in Tehnologija mesa, 53, no. 1 (2012):56-61,
https://doi.org/10.5937/tehmesa1201056J . .
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