TY  - JOUR
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Mandinić, Zoran
AU  - Ćurčić, Marijana
AU  - Ćupić-Miladinović, Dejana
AU  - Antonijević, Biljana
AU  - Matović, Vesna
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3274
AB  - Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vračar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and toothpaste in 3-year-old children in Vračar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries.
AB  - Uvod/Cilj. Fluoridi imaju pozitivan efekat na prevenciju karijesa zuba kao i povećanje čvrstine zubnog emajla. Međutim, njihov unos iznad optimalnog može imati štetne efekte na zube i kosti, posebno kod male dece tokom intenzivnog rasta i razvoja zuba. Cilj ovog rada bio je da se proceni unos fluorida putem vode za piće i paste za zube kod dece uzrasta od tri godine u Beogradu, na teritoriji dve opštine, Vračar i Novi Beograd. Metode. Anketnim upitnicima (n = 40) za roditelje dobijeni su podaci o vrsti vode koju deca piju (česmenska i/ili flaširana), proizvodima koje koriste za čišćenje i negu zuba, učestalosti pranja zuba kao i količini paste za zube koja se koristi po jednom pranju. Sadržaj fluorida u vodi za piće i pastama za zube određen je elektrohemijski sa fluoridnom jonselektivnom elektrodom. Unos fluorida procenjen je korišćenjem matematičkog modela datog od strane Američke agencije za zaštitu životne sredine. Rezultati. Dobijeni rezultati pokazuju da nema statistički značajne razlike u dnevnom unosu fluorida putem vode za piće i paste za zube između dece uzrasta od tri godine na Vračaru i Novom Beogradu (p > 0,05). Međutim, sve procenjene vrednosti unosa fluorida (0,089-0,625 mg/dan) značajno su niže od optimalnog dnevnog unosa za prevenciju karijesa (0,7 mg/dan za decu uzrasta do 4 godine, FNB-Nacionalnog instituta medicine, SAD) i dva do šest puta niže od tolerišućeg gornjeg nivoa unosa fluorida za decu istog uzrasta (1,3 mg/dan, FNBNacionalnog instituta medicine, SAD). Štaviše, izračunati dnevni unosi fluorida izraženi po kilogramu telesne mase potvrđuju veoma nizak unos fluorida kod dece ispitivanih opština u Beogradu, čak značajno niže od preporučenog optimalnog unosa (0,05 mg/kg/dan, EFSA). Zaključak. Ovim preliminarnim istraživanjem pokazano je da je dnevni unos fluorida kod trogodišnjaka u Beogradu značajno niži od tolerišućeg gornjeg nivoa unosa fluorida, čak niži od optimalnog unosa za prevenciju karijesa.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: Preliminary results in Belgrade, Republic of Serbia
T1  - Procena unosa fluorida putem vode za piće i paste za zube kod dece uzrasta od tri godine - preliminarni rezultati u Beogradu, Republika Srbija
VL  - 76
IS  - 6
SP  - 607
EP  - 614
DO  - 10.2298/VSP170721136D
ER  - 

@article{
author = "Đukić-Ćosić, Danijela and Antonijević, Evica and Mandinić, Zoran and Ćurčić, Marijana and Ćupić-Miladinović, Dejana and Antonijević, Biljana and Matović, Vesna",
year = "2019",
abstract = "Background/Aim. Fluoride has beneficial effect on dental caries prevention and enables high hardness of enamel. However, fluoride intake above optimal levels can have adverse effects on teeth and bones, especially in young children during the period of intense growth and teeth development. The aim of this study was to assess fluoride intake from water and toothpaste among 3-year-old children in Belgrade, Serbia, in the municipalities of Vračar and Novi Beograd. Methods. A questionnaire for the parents (n = 40) was used to provide information on the water consumption (tap and/or bottled water) and the brand of toothpaste used by children as well as the frequency of tooth brushing and the amount of toothpaste during brushing. Fluoride concentrations in water and toothpaste samples were determined electrochemically by using fluoride-selective electrode. Fluoride intake was estimated through a mathematical model commonly used by the U.S. Environmental Protection Agency. Results. The obtained results indicate no significant difference in daily fluoride intake through drinking water and toothpaste in 3-year-old children in Vračar (n = 19) compared to Novi Beograd (n = 21) (p > 0.05). However, all estimated fluoride levels (0.089-0.625 mg/day) are significantly lower than the optimal daily intake level for caries protection (0.7 mg/day for children up to 4 years, FNB-USA National Institute of Medicine) and two to six times lower than tolerable upper fluoride level for the children of same age (1.3 mg/day, FNB-USA National Institute of Medicine). Furthermore, calculated daily fluoride intake per kilogram body weight confirm very low fluoride intake by water and toothpaste in children of investigated municipalities in Belgrade, being significantly below the recommended an adequate intake (0.05 mg/kg/day, EFSA). Conclusion. This preliminary study has shown that daily fluoride intake in 3-year-olds is lower than tolerable upper fluoride level, even not sufficient for the prevention of dental caries., Uvod/Cilj. Fluoridi imaju pozitivan efekat na prevenciju karijesa zuba kao i povećanje čvrstine zubnog emajla. Međutim, njihov unos iznad optimalnog može imati štetne efekte na zube i kosti, posebno kod male dece tokom intenzivnog rasta i razvoja zuba. Cilj ovog rada bio je da se proceni unos fluorida putem vode za piće i paste za zube kod dece uzrasta od tri godine u Beogradu, na teritoriji dve opštine, Vračar i Novi Beograd. Metode. Anketnim upitnicima (n = 40) za roditelje dobijeni su podaci o vrsti vode koju deca piju (česmenska i/ili flaširana), proizvodima koje koriste za čišćenje i negu zuba, učestalosti pranja zuba kao i količini paste za zube koja se koristi po jednom pranju. Sadržaj fluorida u vodi za piće i pastama za zube određen je elektrohemijski sa fluoridnom jonselektivnom elektrodom. Unos fluorida procenjen je korišćenjem matematičkog modela datog od strane Američke agencije za zaštitu životne sredine. Rezultati. Dobijeni rezultati pokazuju da nema statistički značajne razlike u dnevnom unosu fluorida putem vode za piće i paste za zube između dece uzrasta od tri godine na Vračaru i Novom Beogradu (p > 0,05). Međutim, sve procenjene vrednosti unosa fluorida (0,089-0,625 mg/dan) značajno su niže od optimalnog dnevnog unosa za prevenciju karijesa (0,7 mg/dan za decu uzrasta do 4 godine, FNB-Nacionalnog instituta medicine, SAD) i dva do šest puta niže od tolerišućeg gornjeg nivoa unosa fluorida za decu istog uzrasta (1,3 mg/dan, FNBNacionalnog instituta medicine, SAD). Štaviše, izračunati dnevni unosi fluorida izraženi po kilogramu telesne mase potvrđuju veoma nizak unos fluorida kod dece ispitivanih opština u Beogradu, čak značajno niže od preporučenog optimalnog unosa (0,05 mg/kg/dan, EFSA). Zaključak. Ovim preliminarnim istraživanjem pokazano je da je dnevni unos fluorida kod trogodišnjaka u Beogradu značajno niži od tolerišućeg gornjeg nivoa unosa fluorida, čak niži od optimalnog unosa za prevenciju karijesa.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: Preliminary results in Belgrade, Republic of Serbia, Procena unosa fluorida putem vode za piće i paste za zube kod dece uzrasta od tri godine - preliminarni rezultati u Beogradu, Republika Srbija",
volume = "76",
number = "6",
pages = "607-614",
doi = "10.2298/VSP170721136D"
}

Đukić-Ćosić, D., Antonijević, E., Mandinić, Z., Ćurčić, M., Ćupić-Miladinović, D., Antonijević, B.,& Matović, V.. (2019). Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: Preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 76(6), 607-614.
https://doi.org/10.2298/VSP170721136D

Đukić-Ćosić D, Antonijević E, Mandinić Z, Ćurčić M, Ćupić-Miladinović D, Antonijević B, Matović V. Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: Preliminary results in Belgrade, Republic of Serbia. in Vojnosanitetski pregled. 2019;76(6):607-614.
doi:10.2298/VSP170721136D .

Đukić-Ćosić, Danijela, Antonijević, Evica, Mandinić, Zoran, Ćurčić, Marijana, Ćupić-Miladinović, Dejana, Antonijević, Biljana, Matović, Vesna, "Assessment of fluoride intake from drinking water and toothpaste in 3-year-olds: Preliminary results in Belgrade, Republic of Serbia" in Vojnosanitetski pregled, 76, no. 6 (2019):607-614,
https://doi.org/10.2298/VSP170721136D . .

TY  - JOUR
AU  - Đorđević, Vladimir
AU  - Wallace, David
AU  - Schweitzer, Amie
AU  - Boricić, Novica
AU  - Knežević, Đorđe
AU  - Matić, Slavko
AU  - Grubor, Nikola
AU  - Kerkez, Mirko
AU  - Radenković, Dejan
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
AU  - Matović, Vesna
AU  - Buha, Aleksandra
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3346
AB  - Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scarce. Some of established risk factors of PC are connected to an increased cadmium (Cd) body burden. Hence, the aim of this study was to investigate the role of this environmental pollutant in PC development by conducting human observational, experimental and in vitro studies. The case-control study included 31 patients with a histologically based diagnosis of exocrine PC subjected to radical surgical intervention as cases and 29 accidental fatalities or subjects who died of a nonmalignant illness as controls. Animal study included two treated groups of Wistar rats (15 and 30 mg Cd/kg b.w) and untreated control group, sacrificed 24 h after single oral exposure. In in vitro study pancreas hTERT-HPNE and AsPC-1 cells were exposed to different Cd concentrations corresponding to levels measured in human cancerous pancreatic tissue. Cd content in cancer tissue significantly differed from the content in healthy controls. Odds ratio levels for PC development were 2.79 (95% CI 0.91-8.50) and 3.44 (95% CI 1.19-9.95) in the third and fourth quartiles of Cd distribution, respectively. Animal study confirmed Cd deposition in pancreatic tissue. In vitro studies revealed that Cd produces disturbances in intrinsic pathway of apoptotic activity and the elevation in oxidative stress in pancreatic cells. This study presents three different lines of evidence pointing towards Cd as an agent responsible for the development of PC.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Environment International
T1  - Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies
VL  - 128
SP  - 353
EP  - 361
DO  - 10.1016/j.envint.2019.04.048
ER  - 

@article{
author = "Đorđević, Vladimir and Wallace, David and Schweitzer, Amie and Boricić, Novica and Knežević, Đorđe and Matić, Slavko and Grubor, Nikola and Kerkez, Mirko and Radenković, Dejan and Bulat, Zorica and Antonijević, Biljana and Matović, Vesna and Buha, Aleksandra",
year = "2019",
abstract = "Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scarce. Some of established risk factors of PC are connected to an increased cadmium (Cd) body burden. Hence, the aim of this study was to investigate the role of this environmental pollutant in PC development by conducting human observational, experimental and in vitro studies. The case-control study included 31 patients with a histologically based diagnosis of exocrine PC subjected to radical surgical intervention as cases and 29 accidental fatalities or subjects who died of a nonmalignant illness as controls. Animal study included two treated groups of Wistar rats (15 and 30 mg Cd/kg b.w) and untreated control group, sacrificed 24 h after single oral exposure. In in vitro study pancreas hTERT-HPNE and AsPC-1 cells were exposed to different Cd concentrations corresponding to levels measured in human cancerous pancreatic tissue. Cd content in cancer tissue significantly differed from the content in healthy controls. Odds ratio levels for PC development were 2.79 (95% CI 0.91-8.50) and 3.44 (95% CI 1.19-9.95) in the third and fourth quartiles of Cd distribution, respectively. Animal study confirmed Cd deposition in pancreatic tissue. In vitro studies revealed that Cd produces disturbances in intrinsic pathway of apoptotic activity and the elevation in oxidative stress in pancreatic cells. This study presents three different lines of evidence pointing towards Cd as an agent responsible for the development of PC.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Environment International",
title = "Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies",
volume = "128",
pages = "353-361",
doi = "10.1016/j.envint.2019.04.048"
}

Đorđević, V., Wallace, D., Schweitzer, A., Boricić, N., Knežević, Đ., Matić, S., Grubor, N., Kerkez, M., Radenković, D., Bulat, Z., Antonijević, B., Matović, V.,& Buha, A.. (2019). Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies. in Environment International
Pergamon-Elsevier Science Ltd, Oxford., 128, 353-361.
https://doi.org/10.1016/j.envint.2019.04.048

Đorđević V, Wallace D, Schweitzer A, Boricić N, Knežević Đ, Matić S, Grubor N, Kerkez M, Radenković D, Bulat Z, Antonijević B, Matović V, Buha A. Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies. in Environment International. 2019;128:353-361.
doi:10.1016/j.envint.2019.04.048 .

Đorđević, Vladimir, Wallace, David, Schweitzer, Amie, Boricić, Novica, Knežević, Đorđe, Matić, Slavko, Grubor, Nikola, Kerkez, Mirko, Radenković, Dejan, Bulat, Zorica, Antonijević, Biljana, Matović, Vesna, Buha, Aleksandra, "Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies" in Environment International, 128 (2019):353-361,
https://doi.org/10.1016/j.envint.2019.04.048 . .

TY  - JOUR
AU  - Buha, Aleksandra
AU  - Jugdaohsingh, R
AU  - Matović, Vesna
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
AU  - Kerns, J.G
AU  - Goodship, A
AU  - Hart, A
AU  - Powell, J.J
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3250
AB  - Exposure to cadmium (Cd) is recognised as one of the risk factors for osteoporosis, although critical exposure levels and exact mechanisms are still unknown. Here, we first confirmed that in male Wistar rats challenged orally with 6 different levels of Cd (0.3–10 mg/kg b.w.), over 28 days, there was a direct dose relationship to bone Cd concentration. Moreover, bone mineral content was significantly diminished by ∼15% (p  lt  0.0001) plateauing already at the lowest exposure level. For the other essential bone elements zinc (Zn) loss was most marked. Having established the sensitive metrics (measures of Cd exposure), we then applied them to 20 randomly selected human femoral head bone samples from 16 independent subjects. Bone Cd concentration was inversely proportional to trabecular bone mineral density and mineral (calcium) content and Zn content of bone, but not the donor's age. Our findings, through direct bone analyses, support the emerging epidemiological view that bone health, adjudged by mineral density, is extremely sensitive to even background levels of environmental Cd. Importantly, however, our data also suggest that Cd may play an even greater role in compromised bone health than prior indirect estimates of exposure could reveal. Environmental Cd may be a substantially determining factor in osteoporosis and large cohort studies with direct bone analyses are now merited.
PB  - Academic Press Inc.
T2  - Environmental Research
T1  - Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data
VL  - 176
DO  - 10.1016/j.envres.2019.108539
ER  - 

@article{
author = "Buha, Aleksandra and Jugdaohsingh, R and Matović, Vesna and Bulat, Zorica and Antonijević, Biljana and Kerns, J.G and Goodship, A and Hart, A and Powell, J.J",
year = "2019",
abstract = "Exposure to cadmium (Cd) is recognised as one of the risk factors for osteoporosis, although critical exposure levels and exact mechanisms are still unknown. Here, we first confirmed that in male Wistar rats challenged orally with 6 different levels of Cd (0.3–10 mg/kg b.w.), over 28 days, there was a direct dose relationship to bone Cd concentration. Moreover, bone mineral content was significantly diminished by ∼15% (p  lt  0.0001) plateauing already at the lowest exposure level. For the other essential bone elements zinc (Zn) loss was most marked. Having established the sensitive metrics (measures of Cd exposure), we then applied them to 20 randomly selected human femoral head bone samples from 16 independent subjects. Bone Cd concentration was inversely proportional to trabecular bone mineral density and mineral (calcium) content and Zn content of bone, but not the donor's age. Our findings, through direct bone analyses, support the emerging epidemiological view that bone health, adjudged by mineral density, is extremely sensitive to even background levels of environmental Cd. Importantly, however, our data also suggest that Cd may play an even greater role in compromised bone health than prior indirect estimates of exposure could reveal. Environmental Cd may be a substantially determining factor in osteoporosis and large cohort studies with direct bone analyses are now merited.",
publisher = "Academic Press Inc.",
journal = "Environmental Research",
title = "Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data",
volume = "176",
doi = "10.1016/j.envres.2019.108539"
}

Buha, A., Jugdaohsingh, R., Matović, V., Bulat, Z., Antonijević, B., Kerns, J.G, Goodship, A., Hart, A.,& Powell, J.J. (2019). Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data. in Environmental Research
Academic Press Inc.., 176.
https://doi.org/10.1016/j.envres.2019.108539

Buha A, Jugdaohsingh R, Matović V, Bulat Z, Antonijević B, Kerns J, Goodship A, Hart A, Powell J. Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data. in Environmental Research. 2019;176.
doi:10.1016/j.envres.2019.108539 .

Buha, Aleksandra, Jugdaohsingh, R, Matović, Vesna, Bulat, Zorica, Antonijević, Biljana, Kerns, J.G, Goodship, A, Hart, A, Powell, J.J, "Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data" in Environmental Research, 176 (2019),
https://doi.org/10.1016/j.envres.2019.108539 . .

TY  - CONF
AU  - Baralić, Katarina
AU  - Jorgovanović, D.
AU  - Matović, Vesna
AU  - Antonijević, Biljana
AU  - Bulat, Zorica
AU  - Ćurčić, Marijana
AU  - Antonijević, Evica
AU  - Đukić-Ćosić, Danijela
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3132
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities
VL  - 295
IS  - Supplement 1
SP  - S237
EP  - S237
DO  - 10.1016/j.toxlet.2018.06.988
ER  - 

@conference{
author = "Baralić, Katarina and Jorgovanović, D. and Matović, Vesna and Antonijević, Biljana and Bulat, Zorica and Ćurčić, Marijana and Antonijević, Evica and Đukić-Ćosić, Danijela",
year = "2018",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities",
volume = "295",
number = "Supplement 1",
pages = "S237-S237",
doi = "10.1016/j.toxlet.2018.06.988"
}

Baralić, K., Jorgovanović, D., Matović, V., Antonijević, B., Bulat, Z., Ćurčić, M., Antonijević, E.,& Đukić-Ćosić, D.. (2018). Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 295(Supplement 1), S237-S237.
https://doi.org/10.1016/j.toxlet.2018.06.988

Baralić K, Jorgovanović D, Matović V, Antonijević B, Bulat Z, Ćurčić M, Antonijević E, Đukić-Ćosić D. Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities. in Toxicology Letters. 2018;295(Supplement 1):S237-S237.
doi:10.1016/j.toxlet.2018.06.988 .

Baralić, Katarina, Jorgovanović, D., Matović, Vesna, Antonijević, Biljana, Bulat, Zorica, Ćurčić, Marijana, Antonijević, Evica, Đukić-Ćosić, Danijela, "Toxicogenomics analysis of phthalates and bisphenol A mixture: Obesity and comorbidities" in Toxicology Letters, 295, no. Supplement 1 (2018):S237-S237,
https://doi.org/10.1016/j.toxlet.2018.06.988 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Buha-Đorđević, Aleksandra
AU  - Milovanović, V.
AU  - Janković, Saša
AU  - Vučinić, Slavica
AU  - Antonijević, Evica
AU  - Đukić-Ćosić, Danijela
AU  - Bulat, Zorica
AU  - Matović, Vesna
AU  - Antonijević, Biljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3126
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys
VL  - 295
IS  - Supplement 1
SP  - S235
EP  - S236
DO  - 10.1016/j.toxlet.2018.06.984
ER  - 

@conference{
author = "Ćurčić, Marijana and Buha-Đorđević, Aleksandra and Milovanović, V. and Janković, Saša and Vučinić, Slavica and Antonijević, Evica and Đukić-Ćosić, Danijela and Bulat, Zorica and Matović, Vesna and Antonijević, Biljana",
year = "2018",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys",
volume = "295",
number = "Supplement 1",
pages = "S235-S236",
doi = "10.1016/j.toxlet.2018.06.984"
}

Ćurčić, M., Buha-Đorđević, A., Milovanović, V., Janković, S., Vučinić, S., Antonijević, E., Đukić-Ćosić, D., Bulat, Z., Matović, V.,& Antonijević, B.. (2018). Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 295(Supplement 1), S235-S236.
https://doi.org/10.1016/j.toxlet.2018.06.984

Ćurčić M, Buha-Đorđević A, Milovanović V, Janković S, Vučinić S, Antonijević E, Đukić-Ćosić D, Bulat Z, Matović V, Antonijević B. Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys. in Toxicology Letters. 2018;295(Supplement 1):S235-S236.
doi:10.1016/j.toxlet.2018.06.984 .

Ćurčić, Marijana, Buha-Đorđević, Aleksandra, Milovanović, V., Janković, Saša, Vučinić, Slavica, Antonijević, Evica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, Antonijević, Biljana, "Effect assessment of target tissue doses of cadmium and decabrominated diphenyl ether on GSH level in kidneys" in Toxicology Letters, 295, no. Supplement 1 (2018):S235-S236,
https://doi.org/10.1016/j.toxlet.2018.06.984 . .

TY  - JOUR
AU  - Milovanović, Vesna
AU  - Buha, Aleksandra
AU  - Matović, Vesna
AU  - Ćurčić, Marijana
AU  - Vučinić, Slavica
AU  - Nakano, Takeshi
AU  - Antonijević, Biljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3176
AB  - Fully brominated diphenyl ether (BDE-209) is a flame retardant widely used in plastics and textiles. Because of its high persistence, humans are exposed to it continuously, mainly via dust ingestion. We investigated effects of BDE-209 on renal function and oxidative stress development in the kidney after subacute exposure in rats. Five groups of animals were given by oral gavage 31.25-500 mg BDE-209/kg b.w./day for 28 days, and relative kidney weight, serum urea and creatinine, and oxidative stress parameters in the kidney were determined. Benchmark-dose approach was used for dose response modeling. Serum creatinine was increased, while results obtained for serum urea were inconclusive. Relative kidney weight was not affected by BDE-209. Kidney reduced glutathione was elevated, while superoxide dismutase activity was not changed after BDE-209 treatment. Also, levels of thiobarbituric acid reactive substances (TBARS) were increased and total -SH groups were decreased, which indicated oxidative imbalance. The critical effect dose (CED)/CEDL ratios for the effects on TBARS and total -SH groups indicated estimated CEDs for these markers can be used in risk assessment of BDE-209. Our study results have shown that a relatively low dose of BDE-209 affects kidney function and that oxidative stress is one of the mechanisms of its nephrotoxicity.
PB  - Springer Heidelberg, Heidelberg
T2  - Environmental Science and Pollution Research
T1  - Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats
VL  - 25
IS  - 8
SP  - 7223
EP  - 7230
DO  - 10.1007/s11356-015-5921-5
ER  - 

@article{
author = "Milovanović, Vesna and Buha, Aleksandra and Matović, Vesna and Ćurčić, Marijana and Vučinić, Slavica and Nakano, Takeshi and Antonijević, Biljana",
year = "2018",
abstract = "Fully brominated diphenyl ether (BDE-209) is a flame retardant widely used in plastics and textiles. Because of its high persistence, humans are exposed to it continuously, mainly via dust ingestion. We investigated effects of BDE-209 on renal function and oxidative stress development in the kidney after subacute exposure in rats. Five groups of animals were given by oral gavage 31.25-500 mg BDE-209/kg b.w./day for 28 days, and relative kidney weight, serum urea and creatinine, and oxidative stress parameters in the kidney were determined. Benchmark-dose approach was used for dose response modeling. Serum creatinine was increased, while results obtained for serum urea were inconclusive. Relative kidney weight was not affected by BDE-209. Kidney reduced glutathione was elevated, while superoxide dismutase activity was not changed after BDE-209 treatment. Also, levels of thiobarbituric acid reactive substances (TBARS) were increased and total -SH groups were decreased, which indicated oxidative imbalance. The critical effect dose (CED)/CEDL ratios for the effects on TBARS and total -SH groups indicated estimated CEDs for these markers can be used in risk assessment of BDE-209. Our study results have shown that a relatively low dose of BDE-209 affects kidney function and that oxidative stress is one of the mechanisms of its nephrotoxicity.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Environmental Science and Pollution Research",
title = "Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats",
volume = "25",
number = "8",
pages = "7223-7230",
doi = "10.1007/s11356-015-5921-5"
}

Milovanović, V., Buha, A., Matović, V., Ćurčić, M., Vučinić, S., Nakano, T.,& Antonijević, B.. (2018). Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats. in Environmental Science and Pollution Research
Springer Heidelberg, Heidelberg., 25(8), 7223-7230.
https://doi.org/10.1007/s11356-015-5921-5

Milovanović V, Buha A, Matović V, Ćurčić M, Vučinić S, Nakano T, Antonijević B. Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats. in Environmental Science and Pollution Research. 2018;25(8):7223-7230.
doi:10.1007/s11356-015-5921-5 .

Milovanović, Vesna, Buha, Aleksandra, Matović, Vesna, Ćurčić, Marijana, Vučinić, Slavica, Nakano, Takeshi, Antonijević, Biljana, "Oxidative stress and renal toxicity after subacute exposure to decabrominated diphenyl ether in Wistar rats" in Environmental Science and Pollution Research, 25, no. 8 (2018):7223-7230,
https://doi.org/10.1007/s11356-015-5921-5 . .

TY  - JOUR
AU  - Buha, Aleksandra
AU  - Matović, Vesna
AU  - Antonijević, Biljana
AU  - Bulat, Zorica
AU  - Ćurčić, Marijana
AU  - Renieri, Elisavet A.
AU  - Tsatsakis, Aristidis
AU  - Schweitzer, Amie
AU  - Wallace, David
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3035
AB  - Humans are exposed to a significant number of chemicals that are suspected to produce disturbances in hormone homeostasis. Hence, in recent decades, there has been a growing interest in endocrine disruptive chemicals. One of the alleged thyroid disrupting substances is cadmium (Cd), a ubiquitous toxic metal shown to act as a thyroid disruptor and carcinogen in both animals and humans. Multiple PubMed searches with core keywords were performed to identify and evaluate appropriate studies which revealed literature suggesting evidence for the link between exposure to Cd and histological and metabolic changes in the thyroid gland. Furthermore, Cd influence on thyroid homeostasis at the peripheral level has also been hypothesized. Both in vivo and in vitro studies revealed that a Cd exposure at environmentally relevant concentrations results in biphasic Cd dose-thyroid response relationships. Development of thyroid tumors following exposure to Cd has been studied mainly using in vitro methodologies. In the thyroid, Cd has been shown to activate or stimulate the activity of various factors, leading to increased cell proliferation and a reduction in normal apoptotic activity. Evidence establishing the association between Cd and thyroid disruption remains ambiguous, with further studies needed to elucidate the issue and improve our understanding of Cd-mediated effects on the thyroid gland.
PB  - MDPI, Basel
T2  - International Journal of Molecular Sciences
T1  - Overview of Cadmium Thyroid Disrupting Effects and Mechanisms
VL  - 19
IS  - 5
DO  - 10.3390/ijms19051501
ER  - 

@article{
author = "Buha, Aleksandra and Matović, Vesna and Antonijević, Biljana and Bulat, Zorica and Ćurčić, Marijana and Renieri, Elisavet A. and Tsatsakis, Aristidis and Schweitzer, Amie and Wallace, David",
year = "2018",
abstract = "Humans are exposed to a significant number of chemicals that are suspected to produce disturbances in hormone homeostasis. Hence, in recent decades, there has been a growing interest in endocrine disruptive chemicals. One of the alleged thyroid disrupting substances is cadmium (Cd), a ubiquitous toxic metal shown to act as a thyroid disruptor and carcinogen in both animals and humans. Multiple PubMed searches with core keywords were performed to identify and evaluate appropriate studies which revealed literature suggesting evidence for the link between exposure to Cd and histological and metabolic changes in the thyroid gland. Furthermore, Cd influence on thyroid homeostasis at the peripheral level has also been hypothesized. Both in vivo and in vitro studies revealed that a Cd exposure at environmentally relevant concentrations results in biphasic Cd dose-thyroid response relationships. Development of thyroid tumors following exposure to Cd has been studied mainly using in vitro methodologies. In the thyroid, Cd has been shown to activate or stimulate the activity of various factors, leading to increased cell proliferation and a reduction in normal apoptotic activity. Evidence establishing the association between Cd and thyroid disruption remains ambiguous, with further studies needed to elucidate the issue and improve our understanding of Cd-mediated effects on the thyroid gland.",
publisher = "MDPI, Basel",
journal = "International Journal of Molecular Sciences",
title = "Overview of Cadmium Thyroid Disrupting Effects and Mechanisms",
volume = "19",
number = "5",
doi = "10.3390/ijms19051501"
}

Buha, A., Matović, V., Antonijević, B., Bulat, Z., Ćurčić, M., Renieri, E. A., Tsatsakis, A., Schweitzer, A.,& Wallace, D.. (2018). Overview of Cadmium Thyroid Disrupting Effects and Mechanisms. in International Journal of Molecular Sciences
MDPI, Basel., 19(5).
https://doi.org/10.3390/ijms19051501

Buha A, Matović V, Antonijević B, Bulat Z, Ćurčić M, Renieri EA, Tsatsakis A, Schweitzer A, Wallace D. Overview of Cadmium Thyroid Disrupting Effects and Mechanisms. in International Journal of Molecular Sciences. 2018;19(5).
doi:10.3390/ijms19051501 .

Buha, Aleksandra, Matović, Vesna, Antonijević, Biljana, Bulat, Zorica, Ćurčić, Marijana, Renieri, Elisavet A., Tsatsakis, Aristidis, Schweitzer, Amie, Wallace, David, "Overview of Cadmium Thyroid Disrupting Effects and Mechanisms" in International Journal of Molecular Sciences, 19, no. 5 (2018),
https://doi.org/10.3390/ijms19051501 . .

TY  - CONF
AU  - Baralić, Katarina
AU  - Ćurčić, Marijana
AU  - Antonijević, Evica
AU  - Bulat, Zorica
AU  - Janković, Saša
AU  - Todorović, Milica
AU  - Milosavljević, Filip
AU  - Kotur-Stevuljević, Jelena
AU  - Kalimanovska, Vesna
AU  - Matović, Vesna
AU  - Antonijević, Biljana
AU  - Đukić-Ćosić, Danijela
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2889
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia
VL  - 280
IS  - Supplement 1
SP  - S179
EP  - S179
DO  - 10.1016/j.toxlet.2017.07.501
ER  - 

@conference{
author = "Baralić, Katarina and Ćurčić, Marijana and Antonijević, Evica and Bulat, Zorica and Janković, Saša and Todorović, Milica and Milosavljević, Filip and Kotur-Stevuljević, Jelena and Kalimanovska, Vesna and Matović, Vesna and Antonijević, Biljana and Đukić-Ćosić, Danijela",
year = "2017",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia",
volume = "280",
number = "Supplement 1",
pages = "S179-S179",
doi = "10.1016/j.toxlet.2017.07.501"
}

Baralić, K., Ćurčić, M., Antonijević, E., Bulat, Z., Janković, S., Todorović, M., Milosavljević, F., Kotur-Stevuljević, J., Kalimanovska, V., Matović, V., Antonijević, B.,& Đukić-Ćosić, D.. (2017). Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 280(Supplement 1), S179-S179.
https://doi.org/10.1016/j.toxlet.2017.07.501

Baralić K, Ćurčić M, Antonijević E, Bulat Z, Janković S, Todorović M, Milosavljević F, Kotur-Stevuljević J, Kalimanovska V, Matović V, Antonijević B, Đukić-Ćosić D. Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia. in Toxicology Letters. 2017;280(Supplement 1):S179-S179.
doi:10.1016/j.toxlet.2017.07.501 .

Baralić, Katarina, Ćurčić, Marijana, Antonijević, Evica, Bulat, Zorica, Janković, Saša, Todorović, Milica, Milosavljević, Filip, Kotur-Stevuljević, Jelena, Kalimanovska, Vesna, Matović, Vesna, Antonijević, Biljana, Đukić-Ćosić, Danijela, "Obesity in relation with erythrocyte lead level in people exposed to environmental lead in Belgrade, Serbia" in Toxicology Letters, 280, no. Supplement 1 (2017):S179-S179,
https://doi.org/10.1016/j.toxlet.2017.07.501 . .

TY  - CONF
AU  - Bulat, Zorica
AU  - Ćurčić, Marijana
AU  - Antunović, Marko
AU  - Vučinić, Slavica
AU  - Buha-Đorđević, Aleksandra
AU  - Janković, Saša
AU  - Nikolić, Dragica
AU  - Matović, Vesna
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Baralić, Katarina
AU  - Antonijević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2887
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level
VL  - 280
IS  - Supplement 1
SP  - S152
EP  - S152
DO  - 10.1016/j.toxlet.2017.07.426
ER  - 

@conference{
author = "Bulat, Zorica and Ćurčić, Marijana and Antunović, Marko and Vučinić, Slavica and Buha-Đorđević, Aleksandra and Janković, Saša and Nikolić, Dragica and Matović, Vesna and Đukić-Ćosić, Danijela and Antonijević, Evica and Baralić, Katarina and Antonijević, Biljana",
year = "2017",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level",
volume = "280",
number = "Supplement 1",
pages = "S152-S152",
doi = "10.1016/j.toxlet.2017.07.426"
}

Bulat, Z., Ćurčić, M., Antunović, M., Vučinić, S., Buha-Đorđević, A., Janković, S., Nikolić, D., Matović, V., Đukić-Ćosić, D., Antonijević, E., Baralić, K.,& Antonijević, B.. (2017). Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 280(Supplement 1), S152-S152.
https://doi.org/10.1016/j.toxlet.2017.07.426

Bulat Z, Ćurčić M, Antunović M, Vučinić S, Buha-Đorđević A, Janković S, Nikolić D, Matović V, Đukić-Ćosić D, Antonijević E, Baralić K, Antonijević B. Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level. in Toxicology Letters. 2017;280(Supplement 1):S152-S152.
doi:10.1016/j.toxlet.2017.07.426 .

Bulat, Zorica, Ćurčić, Marijana, Antunović, Marko, Vučinić, Slavica, Buha-Đorđević, Aleksandra, Janković, Saša, Nikolić, Dragica, Matović, Vesna, Đukić-Ćosić, Danijela, Antonijević, Evica, Baralić, Katarina, Antonijević, Biljana, "Cadmium as oxidative stress inducer in brain of subacutely exposed rats and its implication on zinc level" in Toxicology Letters, 280, no. Supplement 1 (2017):S152-S152,
https://doi.org/10.1016/j.toxlet.2017.07.426 . .

TY  - JOUR
AU  - Bulat, Zorica
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Biljana
AU  - Buha, Aleksandra
AU  - Bulat, Petar
AU  - Pavlović, Zoran
AU  - Matović, Vesna
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3003
AB  - The study was designed to investigate the influence of zinc (Zn) supplementation on cadmium-induced alterations in zinc, copper (Cu), and magnesium (Mg) status in rabbits. For this purpose, the concentrations of cadmium (Cd), Zn, Cu, and Mg were estimated in the blood, liver, kidney, and bone. The rabbits were divided in a control group, a Cd group-animals intoxicated orally with Cd (10mg kg(-1) bw, as aqueous solution of Cd-chloride), and a Cd+ Zn group-animals intoxicated with the same dose of Cd and co-treated with Zn (20 mg kg(-1) bw, as aqueous solution of Zn-sulphate). Solutions were administered orally, every day for 28 days. Sample mineralisation was performed with concentrated nitric acid (HNO3) and perchloric acid (HClO4) (4: 1) and metal concentrations were determined by atomic absorption spectrophotometry (AAS). Zinc supplementation improved some of Cd-induced disturbances in bioelement levels in the investigated tissues. Beneficial effects of Zn on Zn and Cu levels were observed in blood, as well as on the Cu kidney level. The calculated values for Cu/Zn,Mg/Zn, and Mg/Cu ratios in blood suggest that Zn co-treatment reduces Cd-induced changes in bioelement ratios in blood.
PB  - Inst Medical Research & Occupational Health, Zagreb
T2  - Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
T1  - Can zinc supplementation ameliorate cadmium-induced alterations in the bioelement content in rabbits?
VL  - 68
IS  - 1
SP  - 38
EP  - 45
DO  - 10.1515/aiht-2017-68-2919
ER  - 

@article{
author = "Bulat, Zorica and Đukić-Ćosić, Danijela and Antonijević, Biljana and Buha, Aleksandra and Bulat, Petar and Pavlović, Zoran and Matović, Vesna",
year = "2017",
abstract = "The study was designed to investigate the influence of zinc (Zn) supplementation on cadmium-induced alterations in zinc, copper (Cu), and magnesium (Mg) status in rabbits. For this purpose, the concentrations of cadmium (Cd), Zn, Cu, and Mg were estimated in the blood, liver, kidney, and bone. The rabbits were divided in a control group, a Cd group-animals intoxicated orally with Cd (10mg kg(-1) bw, as aqueous solution of Cd-chloride), and a Cd+ Zn group-animals intoxicated with the same dose of Cd and co-treated with Zn (20 mg kg(-1) bw, as aqueous solution of Zn-sulphate). Solutions were administered orally, every day for 28 days. Sample mineralisation was performed with concentrated nitric acid (HNO3) and perchloric acid (HClO4) (4: 1) and metal concentrations were determined by atomic absorption spectrophotometry (AAS). Zinc supplementation improved some of Cd-induced disturbances in bioelement levels in the investigated tissues. Beneficial effects of Zn on Zn and Cu levels were observed in blood, as well as on the Cu kidney level. The calculated values for Cu/Zn,Mg/Zn, and Mg/Cu ratios in blood suggest that Zn co-treatment reduces Cd-induced changes in bioelement ratios in blood.",
publisher = "Inst Medical Research & Occupational Health, Zagreb",
journal = "Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology",
title = "Can zinc supplementation ameliorate cadmium-induced alterations in the bioelement content in rabbits?",
volume = "68",
number = "1",
pages = "38-45",
doi = "10.1515/aiht-2017-68-2919"
}

Bulat, Z., Đukić-Ćosić, D., Antonijević, B., Buha, A., Bulat, P., Pavlović, Z.,& Matović, V.. (2017). Can zinc supplementation ameliorate cadmium-induced alterations in the bioelement content in rabbits?. in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology
Inst Medical Research & Occupational Health, Zagreb., 68(1), 38-45.
https://doi.org/10.1515/aiht-2017-68-2919

Bulat Z, Đukić-Ćosić D, Antonijević B, Buha A, Bulat P, Pavlović Z, Matović V. Can zinc supplementation ameliorate cadmium-induced alterations in the bioelement content in rabbits?. in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology. 2017;68(1):38-45.
doi:10.1515/aiht-2017-68-2919 .

Bulat, Zorica, Đukić-Ćosić, Danijela, Antonijević, Biljana, Buha, Aleksandra, Bulat, Petar, Pavlović, Zoran, Matović, Vesna, "Can zinc supplementation ameliorate cadmium-induced alterations in the bioelement content in rabbits?" in Arhiv za higijenu rada i toksikologiju - Archives of Industrial Hygiene and Toxicology, 68, no. 1 (2017):38-45,
https://doi.org/10.1515/aiht-2017-68-2919 . .

TY  - JOUR
AU  - Renieri, Elisavet A.
AU  - Sfakianakis, Dimitris G.
AU  - Alegakis, Athanasios A.
AU  - Safenkova, Irina V.
AU  - Buha, Aleksandra
AU  - Matović, Vesna
AU  - Tzardi, Maria
AU  - Dzantiev, Boris B.
AU  - Divanach, Pascal
AU  - Kentouri, Maroudio
AU  - Tsatsakis, Aristidis
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2971
AB  - Cadmium (Cd) has proved to be associated with numerous toxic effects in aquatic organisms via waterbome exposure. With a view to investigate Cd toxicity along a broad spectrum of exposures reaching from environmental to toxic, we employed adult zebrafish (Danio rerio) for an in vivo study. A number of 10 fish per tank were placed in 40 L tanks and were exposed for 30 days to 0.0, 5.0, 25, 50, 75, 100 and 1000 mu g Cd per liter. There were 2 tanks for each Cd exposure (duplicate experiment). Mortality was recorded daily, dead fish were collected and tissue samples were obtained for histologic observation, whereas remaining tissues were stored for Cd burden determination. Surviving fish were collected at the end of the experiment. Median overall survival (OS) in days was found to be 9.0, 11.0, 8.0 and 7.0 for 25 mu g/L, 50 mu g/L, 75 mu g/L and 100 mu g/L respectively, with all of them showing mortality greater than 50%. Remarkably, fish exposed to the highest Cd concentration (1000 mu g/L) survived the longest exhibiting a mean OS of 29.2 days. Cd determination in fish tissue was conducted with an in house ICP-MS method and levels ranged from 3.1 to 29.1 ng/mg. Log Cd tissue levels were significantly correlated with the log Cd exposure levels (r = 0.535, p  lt  0.001). The highest Cd burden was determined for fish exposed to 1000 mu g Cd /L (mean = 12.2 ng/mg). Histopathology supported these results. Our findings disclose a deviation in toxic responses through the range of Cd concentrations, leading to nonlinear responses. These differentiated responses, could be linked to hormesis phenomena.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Environmental Research
T1  - Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study
VL  - 157
SP  - 173
EP  - 181
DO  - 10.1016/j.envres.2017.05.021
ER  - 

@article{
author = "Renieri, Elisavet A. and Sfakianakis, Dimitris G. and Alegakis, Athanasios A. and Safenkova, Irina V. and Buha, Aleksandra and Matović, Vesna and Tzardi, Maria and Dzantiev, Boris B. and Divanach, Pascal and Kentouri, Maroudio and Tsatsakis, Aristidis",
year = "2017",
abstract = "Cadmium (Cd) has proved to be associated with numerous toxic effects in aquatic organisms via waterbome exposure. With a view to investigate Cd toxicity along a broad spectrum of exposures reaching from environmental to toxic, we employed adult zebrafish (Danio rerio) for an in vivo study. A number of 10 fish per tank were placed in 40 L tanks and were exposed for 30 days to 0.0, 5.0, 25, 50, 75, 100 and 1000 mu g Cd per liter. There were 2 tanks for each Cd exposure (duplicate experiment). Mortality was recorded daily, dead fish were collected and tissue samples were obtained for histologic observation, whereas remaining tissues were stored for Cd burden determination. Surviving fish were collected at the end of the experiment. Median overall survival (OS) in days was found to be 9.0, 11.0, 8.0 and 7.0 for 25 mu g/L, 50 mu g/L, 75 mu g/L and 100 mu g/L respectively, with all of them showing mortality greater than 50%. Remarkably, fish exposed to the highest Cd concentration (1000 mu g/L) survived the longest exhibiting a mean OS of 29.2 days. Cd determination in fish tissue was conducted with an in house ICP-MS method and levels ranged from 3.1 to 29.1 ng/mg. Log Cd tissue levels were significantly correlated with the log Cd exposure levels (r = 0.535, p  lt  0.001). The highest Cd burden was determined for fish exposed to 1000 mu g Cd /L (mean = 12.2 ng/mg). Histopathology supported these results. Our findings disclose a deviation in toxic responses through the range of Cd concentrations, leading to nonlinear responses. These differentiated responses, could be linked to hormesis phenomena.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Environmental Research",
title = "Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study",
volume = "157",
pages = "173-181",
doi = "10.1016/j.envres.2017.05.021"
}

Renieri, E. A., Sfakianakis, D. G., Alegakis, A. A., Safenkova, I. V., Buha, A., Matović, V., Tzardi, M., Dzantiev, B. B., Divanach, P., Kentouri, M.,& Tsatsakis, A.. (2017). Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study. in Environmental Research
Academic Press Inc Elsevier Science, San Diego., 157, 173-181.
https://doi.org/10.1016/j.envres.2017.05.021

Renieri EA, Sfakianakis DG, Alegakis AA, Safenkova IV, Buha A, Matović V, Tzardi M, Dzantiev BB, Divanach P, Kentouri M, Tsatsakis A. Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study. in Environmental Research. 2017;157:173-181.
doi:10.1016/j.envres.2017.05.021 .

Renieri, Elisavet A., Sfakianakis, Dimitris G., Alegakis, Athanasios A., Safenkova, Irina V., Buha, Aleksandra, Matović, Vesna, Tzardi, Maria, Dzantiev, Boris B., Divanach, Pascal, Kentouri, Maroudio, Tsatsakis, Aristidis, "Nonlinear responses to waterborne cadmium exposure in zebrafish. An in vivo study" in Environmental Research, 157 (2017):173-181,
https://doi.org/10.1016/j.envres.2017.05.021 . .

TY  - JOUR
AU  - Ćurčić, Marijana
AU  - Buha, Aleksandra
AU  - Stanković, Sanja
AU  - Milovanović, Vesna
AU  - Bulat, Zorica
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Vucnić, Slavica
AU  - Matović, Vesna
AU  - Antonijević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2948
AB  - The objective of this study was to assess toxicity of Cd and BDE-209 mixture on haematological parameters in subacutely exposed rats and to determine the presence and type of interactions between these two chemicals using multiple factorial regression analysis. Furthermore, for the assessment of interaction type, an isobologram based methodology was applied and compared with multiple factorial regression analysis. Chemicals were given by oral gavage to the male Wistar rats weighing 200-240g for 28 days. Animals were divided in 16 groups (8/group): control vehiculum group, three groups of rats were treated with 2.5, 7.5 or 15 mg Cd/kg/day. These doses were chosen on the bases of literature data and reflect relatively high Cd environmental exposure, three groups of rats were treated with 1000, 2000 or 4000 mg BDE-209/kg/bw/day, doses proved to induce toxic effects in rats. Furthermore, nine groups of animals were treated with different mixtures of Cd and BDE-209 containing doses of Cd and BDE-209 stated above. Blood samples were taken at the end of experiment and red blood cells, white blood cells and platelets counts were determined. For interaction assessment multiple factorial regression analysis and fitted isobologram approach were used. In this study, we focused on multiple factorial regression analysis as a method for interaction assessment. We also investigated the interactions between Cd and BDE-209 by the derived model for the description of the obtained fitted isobologram curves. Current study indicated that co-exposure to Cd and BDE-209 can result in significant decrease in RBC count, increase in WBC count and decrease in PLT count, when compared with controls. Multiple factorial regression analysis used for the assessment of interactions type between Cd and BDE-209 indicated synergism for the effect on RBC count and no interactions i.e. additivity for the effects on WBC and PLT counts. On the other hand, isobologram based approach showed slight antagonism for the effects on RBC and WBC while no interactions were proved for the joint effect on PLT count. These results confirm that the assessment of interactions between chemicals in the mixture greatly depends on the concept or method used for this evaluation.
PB  - Elsevier Ireland Ltd, Clare
T2  - Toxicology and Industrial Health
T1  - Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis
VL  - 376
SP  - 120
EP  - 125
DO  - 10.1016/j.tox.2016.05.011
ER  - 

@article{
author = "Ćurčić, Marijana and Buha, Aleksandra and Stanković, Sanja and Milovanović, Vesna and Bulat, Zorica and Đukić-Ćosić, Danijela and Antonijević, Evica and Vucnić, Slavica and Matović, Vesna and Antonijević, Biljana",
year = "2017",
abstract = "The objective of this study was to assess toxicity of Cd and BDE-209 mixture on haematological parameters in subacutely exposed rats and to determine the presence and type of interactions between these two chemicals using multiple factorial regression analysis. Furthermore, for the assessment of interaction type, an isobologram based methodology was applied and compared with multiple factorial regression analysis. Chemicals were given by oral gavage to the male Wistar rats weighing 200-240g for 28 days. Animals were divided in 16 groups (8/group): control vehiculum group, three groups of rats were treated with 2.5, 7.5 or 15 mg Cd/kg/day. These doses were chosen on the bases of literature data and reflect relatively high Cd environmental exposure, three groups of rats were treated with 1000, 2000 or 4000 mg BDE-209/kg/bw/day, doses proved to induce toxic effects in rats. Furthermore, nine groups of animals were treated with different mixtures of Cd and BDE-209 containing doses of Cd and BDE-209 stated above. Blood samples were taken at the end of experiment and red blood cells, white blood cells and platelets counts were determined. For interaction assessment multiple factorial regression analysis and fitted isobologram approach were used. In this study, we focused on multiple factorial regression analysis as a method for interaction assessment. We also investigated the interactions between Cd and BDE-209 by the derived model for the description of the obtained fitted isobologram curves. Current study indicated that co-exposure to Cd and BDE-209 can result in significant decrease in RBC count, increase in WBC count and decrease in PLT count, when compared with controls. Multiple factorial regression analysis used for the assessment of interactions type between Cd and BDE-209 indicated synergism for the effect on RBC count and no interactions i.e. additivity for the effects on WBC and PLT counts. On the other hand, isobologram based approach showed slight antagonism for the effects on RBC and WBC while no interactions were proved for the joint effect on PLT count. These results confirm that the assessment of interactions between chemicals in the mixture greatly depends on the concept or method used for this evaluation.",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology and Industrial Health",
title = "Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis",
volume = "376",
pages = "120-125",
doi = "10.1016/j.tox.2016.05.011"
}

Ćurčić, M., Buha, A., Stanković, S., Milovanović, V., Bulat, Z., Đukić-Ćosić, D., Antonijević, E., Vucnić, S., Matović, V.,& Antonijević, B.. (2017). Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis. in Toxicology and Industrial Health
Elsevier Ireland Ltd, Clare., 376, 120-125.
https://doi.org/10.1016/j.tox.2016.05.011

Ćurčić M, Buha A, Stanković S, Milovanović V, Bulat Z, Đukić-Ćosić D, Antonijević E, Vucnić S, Matović V, Antonijević B. Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis. in Toxicology and Industrial Health. 2017;376:120-125.
doi:10.1016/j.tox.2016.05.011 .

Ćurčić, Marijana, Buha, Aleksandra, Stanković, Sanja, Milovanović, Vesna, Bulat, Zorica, Đukić-Ćosić, Danijela, Antonijević, Evica, Vucnić, Slavica, Matović, Vesna, Antonijević, Biljana, "Interactions between cadmium and decabrominated diphenyl ether on blood cells count in rats-Multiple factorial regression analysis" in Toxicology and Industrial Health, 376 (2017):120-125,
https://doi.org/10.1016/j.tox.2016.05.011 . .

TY  - CONF
AU  - Matović, Vesna
AU  - Buha, Aleksandra
AU  - Ćurčić, Marijana
AU  - Bulat, Zorica
AU  - Antonijević, Biljana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2880
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Environmental pollutants as endocrine disrupters: The effect of Cd, PCBs and PBDEs on thyroid function
VL  - 280
IS  - Supplement 1
SP  - S168
EP  - S168
DO  - 10.1016/j.toxlet.2017.07.471
ER  - 

@conference{
author = "Matović, Vesna and Buha, Aleksandra and Ćurčić, Marijana and Bulat, Zorica and Antonijević, Biljana",
year = "2017",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Environmental pollutants as endocrine disrupters: The effect of Cd, PCBs and PBDEs on thyroid function",
volume = "280",
number = "Supplement 1",
pages = "S168-S168",
doi = "10.1016/j.toxlet.2017.07.471"
}

Matović, V., Buha, A., Ćurčić, M., Bulat, Z.,& Antonijević, B.. (2017). Environmental pollutants as endocrine disrupters: The effect of Cd, PCBs and PBDEs on thyroid function. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 280(Supplement 1), S168-S168.
https://doi.org/10.1016/j.toxlet.2017.07.471

Matović V, Buha A, Ćurčić M, Bulat Z, Antonijević B. Environmental pollutants as endocrine disrupters: The effect of Cd, PCBs and PBDEs on thyroid function. in Toxicology Letters. 2017;280(Supplement 1):S168-S168.
doi:10.1016/j.toxlet.2017.07.471 .

Matović, Vesna, Buha, Aleksandra, Ćurčić, Marijana, Bulat, Zorica, Antonijević, Biljana, "Environmental pollutants as endocrine disrupters: The effect of Cd, PCBs and PBDEs on thyroid function" in Toxicology Letters, 280, no. Supplement 1 (2017):S168-S168,
https://doi.org/10.1016/j.toxlet.2017.07.471 . .

TY  - JOUR
AU  - Buha, Aleksandra
AU  - Wallace, David
AU  - Matović, Vesna
AU  - Schweitzer, Amie
AU  - Oluić, Branislav
AU  - Micić, Dušan
AU  - Đorđević, Vladimir
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2836
AB  - Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scant. Exposure to cadmium (Cd), a ubiquitous metal associated with well-established toxic and carcinogenic properties, has been hypothesized to one putative cause of PC. Hence, we analyzed recently published observational studies, meta-analyses, and experimental animal and in vitro studies with the aim of summarizing the evidence of Cd involvement in PC development and describing the possible mechanisms. Consolidation of epidemiological data on PC and exposure to Cd indicated a significant association with an elevated risk of PC among general population exposed to Cd. Cadmium exposure of laboratory animals was showed to cause PC supporting the findings suggested by human studies. The concordance with human and animal studies is buttressed by in vitro studies, although in vitro data interpretation is problematic. In most instances, only significant effects are reported, and the concentrations of Cd are excessive, which would skew interpretation. Previous reports suggest that oxidative stress, apoptotic changes, and DNA cross-linking and hypermethylation are involved in Cd-mediated carcinogenesis. Undoubtedly, a significant amount of work is still needed to achieve a better understanding of the Cd involvement in pancreatic cancer which could facilitate prevention, diagnosis, and therapy of this fatal disease.
PB  - Hindawi Ltd, London
T2  - Biomed Research International
T1  - Cadmium Exposure as a Putative Risk Factor for the Development of Pancreatic Cancer: Three Different Lines of Evidence
DO  - 10.1155/2017/1981837
ER  - 

@article{
author = "Buha, Aleksandra and Wallace, David and Matović, Vesna and Schweitzer, Amie and Oluić, Branislav and Micić, Dušan and Đorđević, Vladimir",
year = "2017",
abstract = "Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scant. Exposure to cadmium (Cd), a ubiquitous metal associated with well-established toxic and carcinogenic properties, has been hypothesized to one putative cause of PC. Hence, we analyzed recently published observational studies, meta-analyses, and experimental animal and in vitro studies with the aim of summarizing the evidence of Cd involvement in PC development and describing the possible mechanisms. Consolidation of epidemiological data on PC and exposure to Cd indicated a significant association with an elevated risk of PC among general population exposed to Cd. Cadmium exposure of laboratory animals was showed to cause PC supporting the findings suggested by human studies. The concordance with human and animal studies is buttressed by in vitro studies, although in vitro data interpretation is problematic. In most instances, only significant effects are reported, and the concentrations of Cd are excessive, which would skew interpretation. Previous reports suggest that oxidative stress, apoptotic changes, and DNA cross-linking and hypermethylation are involved in Cd-mediated carcinogenesis. Undoubtedly, a significant amount of work is still needed to achieve a better understanding of the Cd involvement in pancreatic cancer which could facilitate prevention, diagnosis, and therapy of this fatal disease.",
publisher = "Hindawi Ltd, London",
journal = "Biomed Research International",
title = "Cadmium Exposure as a Putative Risk Factor for the Development of Pancreatic Cancer: Three Different Lines of Evidence",
doi = "10.1155/2017/1981837"
}

Buha, A., Wallace, D., Matović, V., Schweitzer, A., Oluić, B., Micić, D.,& Đorđević, V.. (2017). Cadmium Exposure as a Putative Risk Factor for the Development of Pancreatic Cancer: Three Different Lines of Evidence. in Biomed Research International
Hindawi Ltd, London..
https://doi.org/10.1155/2017/1981837

Buha A, Wallace D, Matović V, Schweitzer A, Oluić B, Micić D, Đorđević V. Cadmium Exposure as a Putative Risk Factor for the Development of Pancreatic Cancer: Three Different Lines of Evidence. in Biomed Research International. 2017;.
doi:10.1155/2017/1981837 .

Buha, Aleksandra, Wallace, David, Matović, Vesna, Schweitzer, Amie, Oluić, Branislav, Micić, Dušan, Đorđević, Vladimir, "Cadmium Exposure as a Putative Risk Factor for the Development of Pancreatic Cancer: Three Different Lines of Evidence" in Biomed Research International (2017),
https://doi.org/10.1155/2017/1981837 . .

TY  - JOUR
AU  - Anđelković, Milena
AU  - Buha, Aleksandra
AU  - Vukomanović, Predrag
AU  - Matović, Vesna
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2761
AB  - Human immunodeficiency virus (HIV), isolated in 1983 by Paster Institute researches, has been recognised as the cause of million fatalies in 21st century. Initial monotherapy failed to show promising results, however, with the development of highly active antiretroviral therapy new era of HIV treatment has started. This new approach resulted in extended life time, reduced development of virus resistance as well as morbidity and mortality of HIV patients. Antiretroviral therapy is longlife and connected with serious adverse and toxic effects. Mitochondrial toxicity can be manifested as periferal lipoathrophy, hepatic steatosis, lactic acidosis, neuropathy and miopathy. Metabolic features associated with lipodystrophy include hypertriglyceridaemia, hypercholesterolaemia, insuline resistance and abnormal glucose tolerance. Hepatotoxicity, nephrotoxicity, osteopenia, rash and gastrointestinal symptoms can also occur during antiretroviral therapy. The aim od this work was to present the most important adverse and toxic effects of drugs used in HIV therapy.
AB  - Virus humane imunodeficijencije, izolovan zahvaljujući istraživačima Paster Instituta 1983. godine, uzročnik je milionskih žrtava u XXI veku. Kako inicijalna monoterapija nije uspela da pokaže zavidne rezultate, razvojem visoko aktivne antiretrovirusne terapije započeta je nova era HIV terapije. Nov pristup lečenju produžio je životni vek obolelih, smanjio pojavu rezistencija kao i stopu morbiditeta i mortaliteta obolelih. Antiretrovirusna terapija je doživotna i nosi sa sobom ozbiljne neželjene i toksične efekte. Mitohondrijska toksičnost može se ispoljiti kao periferna lipoatrofija, hepatična steatoza, laktična acidoza, neuropatija i miopatija. Metabolički poremaćaji udruženi sa lipodistrofijom uključuju hipertrigliceridemiju, hiperholestirolemiju, insulinsku rezistenciju i abnormalnu glukoznu toleranciju. Hepatotoksičnost, nefrotoksičnost, ostepenija, pojava raša i smetnje na nivou gastroinestinalnog trakta takođe se mogu javiti pri primeni antiretrovirusne terapije. Cilj ovoga rada je bio da da prikaz najznačajnijih neželjenih i toksičnih efekata lekova koji se koriste u terapiji HIV-a.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Safety of antiretroviral drugs
T1  - Bezbednost primene lekova koji se koriste u terapiji HIV infekcije
VL  - 66
IS  - 4
SP  - 161
EP  - 173
DO  - 10.5937/arhfarm1604161A
ER  - 

@article{
author = "Anđelković, Milena and Buha, Aleksandra and Vukomanović, Predrag and Matović, Vesna",
year = "2016",
abstract = "Human immunodeficiency virus (HIV), isolated in 1983 by Paster Institute researches, has been recognised as the cause of million fatalies in 21st century. Initial monotherapy failed to show promising results, however, with the development of highly active antiretroviral therapy new era of HIV treatment has started. This new approach resulted in extended life time, reduced development of virus resistance as well as morbidity and mortality of HIV patients. Antiretroviral therapy is longlife and connected with serious adverse and toxic effects. Mitochondrial toxicity can be manifested as periferal lipoathrophy, hepatic steatosis, lactic acidosis, neuropathy and miopathy. Metabolic features associated with lipodystrophy include hypertriglyceridaemia, hypercholesterolaemia, insuline resistance and abnormal glucose tolerance. Hepatotoxicity, nephrotoxicity, osteopenia, rash and gastrointestinal symptoms can also occur during antiretroviral therapy. The aim od this work was to present the most important adverse and toxic effects of drugs used in HIV therapy., Virus humane imunodeficijencije, izolovan zahvaljujući istraživačima Paster Instituta 1983. godine, uzročnik je milionskih žrtava u XXI veku. Kako inicijalna monoterapija nije uspela da pokaže zavidne rezultate, razvojem visoko aktivne antiretrovirusne terapije započeta je nova era HIV terapije. Nov pristup lečenju produžio je životni vek obolelih, smanjio pojavu rezistencija kao i stopu morbiditeta i mortaliteta obolelih. Antiretrovirusna terapija je doživotna i nosi sa sobom ozbiljne neželjene i toksične efekte. Mitohondrijska toksičnost može se ispoljiti kao periferna lipoatrofija, hepatična steatoza, laktična acidoza, neuropatija i miopatija. Metabolički poremaćaji udruženi sa lipodistrofijom uključuju hipertrigliceridemiju, hiperholestirolemiju, insulinsku rezistenciju i abnormalnu glukoznu toleranciju. Hepatotoksičnost, nefrotoksičnost, ostepenija, pojava raša i smetnje na nivou gastroinestinalnog trakta takođe se mogu javiti pri primeni antiretrovirusne terapije. Cilj ovoga rada je bio da da prikaz najznačajnijih neželjenih i toksičnih efekata lekova koji se koriste u terapiji HIV-a.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Safety of antiretroviral drugs, Bezbednost primene lekova koji se koriste u terapiji HIV infekcije",
volume = "66",
number = "4",
pages = "161-173",
doi = "10.5937/arhfarm1604161A"
}

Anđelković, M., Buha, A., Vukomanović, P.,& Matović, V.. (2016). Safety of antiretroviral drugs. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 66(4), 161-173.
https://doi.org/10.5937/arhfarm1604161A

Anđelković M, Buha A, Vukomanović P, Matović V. Safety of antiretroviral drugs. in Arhiv za farmaciju. 2016;66(4):161-173.
doi:10.5937/arhfarm1604161A .

Anđelković, Milena, Buha, Aleksandra, Vukomanović, Predrag, Matović, Vesna, "Safety of antiretroviral drugs" in Arhiv za farmaciju, 66, no. 4 (2016):161-173,
https://doi.org/10.5937/arhfarm1604161A . .

TY  - CONF
AU  - Đorđević, Vladimir
AU  - Knežević, D.
AU  - Matić, S.
AU  - Kerkez, Mirko
AU  - Zarić, N.
AU  - Grubor, Nikica
AU  - Bidzić, N.
AU  - Boricić, Novica
AU  - Boricić, I.
AU  - Matović, Vesna
AU  - Buha, Aleksandra
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2666
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Cadmium in human pancreatic cancer - preliminary report
VL  - 258
IS  - Supplement
SP  - S92
EP  - S93
DO  - 10.1016/j.toxlet.2016.06.1406
ER  - 

@conference{
author = "Đorđević, Vladimir and Knežević, D. and Matić, S. and Kerkez, Mirko and Zarić, N. and Grubor, Nikica and Bidzić, N. and Boricić, Novica and Boricić, I. and Matović, Vesna and Buha, Aleksandra",
year = "2016",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Cadmium in human pancreatic cancer - preliminary report",
volume = "258",
number = "Supplement",
pages = "S92-S93",
doi = "10.1016/j.toxlet.2016.06.1406"
}

Đorđević, V., Knežević, D., Matić, S., Kerkez, M., Zarić, N., Grubor, N., Bidzić, N., Boricić, N., Boricić, I., Matović, V.,& Buha, A.. (2016). Cadmium in human pancreatic cancer - preliminary report. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 258(Supplement), S92-S93.
https://doi.org/10.1016/j.toxlet.2016.06.1406

Đorđević V, Knežević D, Matić S, Kerkez M, Zarić N, Grubor N, Bidzić N, Boricić N, Boricić I, Matović V, Buha A. Cadmium in human pancreatic cancer - preliminary report. in Toxicology Letters. 2016;258(Supplement):S92-S93.
doi:10.1016/j.toxlet.2016.06.1406 .

Đorđević, Vladimir, Knežević, D., Matić, S., Kerkez, Mirko, Zarić, N., Grubor, Nikica, Bidzić, N., Boricić, Novica, Boricić, I., Matović, Vesna, Buha, Aleksandra, "Cadmium in human pancreatic cancer - preliminary report" in Toxicology Letters, 258, no. Supplement (2016):S92-S93,
https://doi.org/10.1016/j.toxlet.2016.06.1406 . .

TY  - CONF
AU  - Buha, Aleksandra
AU  - Milovanović, Vladimir
AU  - Antonijević, Biljana
AU  - Ćurčić, Marijana
AU  - Bulat, Zorica
AU  - Đukić-Ćosić, Danijela
AU  - Matović, Vesna
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2659
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - The hematotoxicity of Cd and PCBs mixture: Employing the rat experimental model to evaluate the effects on blood cells count
VL  - 258
IS  - Supplement
SP  - S319
EP  - S319
DO  - 10.1016/j.toxlet.2016.06.2086
ER  - 

@conference{
author = "Buha, Aleksandra and Milovanović, Vladimir and Antonijević, Biljana and Ćurčić, Marijana and Bulat, Zorica and Đukić-Ćosić, Danijela and Matović, Vesna",
year = "2016",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "The hematotoxicity of Cd and PCBs mixture: Employing the rat experimental model to evaluate the effects on blood cells count",
volume = "258",
number = "Supplement",
pages = "S319-S319",
doi = "10.1016/j.toxlet.2016.06.2086"
}

Buha, A., Milovanović, V., Antonijević, B., Ćurčić, M., Bulat, Z., Đukić-Ćosić, D.,& Matović, V.. (2016). The hematotoxicity of Cd and PCBs mixture: Employing the rat experimental model to evaluate the effects on blood cells count. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 258(Supplement), S319-S319.
https://doi.org/10.1016/j.toxlet.2016.06.2086

Buha A, Milovanović V, Antonijević B, Ćurčić M, Bulat Z, Đukić-Ćosić D, Matović V. The hematotoxicity of Cd and PCBs mixture: Employing the rat experimental model to evaluate the effects on blood cells count. in Toxicology Letters. 2016;258(Supplement):S319-S319.
doi:10.1016/j.toxlet.2016.06.2086 .

Buha, Aleksandra, Milovanović, Vladimir, Antonijević, Biljana, Ćurčić, Marijana, Bulat, Zorica, Đukić-Ćosić, Danijela, Matović, Vesna, "The hematotoxicity of Cd and PCBs mixture: Employing the rat experimental model to evaluate the effects on blood cells count" in Toxicology Letters, 258, no. Supplement (2016):S319-S319,
https://doi.org/10.1016/j.toxlet.2016.06.2086 . .

TY  - CONF
AU  - Đukić-Ćosić, Danijela
AU  - Antonijević, Evica
AU  - Ćurčić, Marijana
AU  - Lazarević, L.
AU  - Jorgovanović, D.
AU  - Vidosavljević, M.
AU  - Janković, Saša
AU  - Bulat, Zorica
AU  - Buha, Aleksandra
AU  - Matović, Vesna
AU  - Antonijević, Biljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2657
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study
VL  - 258
IS  - Supplement
SP  - S206
EP  - S206
DO  - 10.1016/j.toxlet.2016.06.1750
ER  - 

@conference{
author = "Đukić-Ćosić, Danijela and Antonijević, Evica and Ćurčić, Marijana and Lazarević, L. and Jorgovanović, D. and Vidosavljević, M. and Janković, Saša and Bulat, Zorica and Buha, Aleksandra and Matović, Vesna and Antonijević, Biljana",
year = "2016",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study",
volume = "258",
number = "Supplement",
pages = "S206-S206",
doi = "10.1016/j.toxlet.2016.06.1750"
}

Đukić-Ćosić, D., Antonijević, E., Ćurčić, M., Lazarević, L., Jorgovanović, D., Vidosavljević, M., Janković, S., Bulat, Z., Buha, A., Matović, V.,& Antonijević, B.. (2016). Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 258(Supplement), S206-S206.
https://doi.org/10.1016/j.toxlet.2016.06.1750

Đukić-Ćosić D, Antonijević E, Ćurčić M, Lazarević L, Jorgovanović D, Vidosavljević M, Janković S, Bulat Z, Buha A, Matović V, Antonijević B. Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study. in Toxicology Letters. 2016;258(Supplement):S206-S206.
doi:10.1016/j.toxlet.2016.06.1750 .

Đukić-Ćosić, Danijela, Antonijević, Evica, Ćurčić, Marijana, Lazarević, L., Jorgovanović, D., Vidosavljević, M., Janković, Saša, Bulat, Zorica, Buha, Aleksandra, Matović, Vesna, Antonijević, Biljana, "Assessment of mercury intake via fish and fish products among children in Belgrade, Serbia: A pilot study" in Toxicology Letters, 258, no. Supplement (2016):S206-S206,
https://doi.org/10.1016/j.toxlet.2016.06.1750 . .

TY  - CONF
AU  - Buha, Aleksandra
AU  - Powell, J.J
AU  - Jugdaohsingh, R.
AU  - Matović, Vesna
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2684
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Damaging cadmium actions in bone tissue-is there a dose dependence?
VL  - 259
IS  - Supplement
SP  - S170
EP  - S171
DO  - 10.1016/j.toxlet.2016.07.727
ER  - 

@conference{
author = "Buha, Aleksandra and Powell, J.J and Jugdaohsingh, R. and Matović, Vesna",
year = "2016",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Damaging cadmium actions in bone tissue-is there a dose dependence?",
volume = "259",
number = "Supplement",
pages = "S170-S171",
doi = "10.1016/j.toxlet.2016.07.727"
}

Buha, A., Powell, J.J, Jugdaohsingh, R.,& Matović, V.. (2016). Damaging cadmium actions in bone tissue-is there a dose dependence?. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 259(Supplement), S170-S171.
https://doi.org/10.1016/j.toxlet.2016.07.727

Buha A, Powell J, Jugdaohsingh R, Matović V. Damaging cadmium actions in bone tissue-is there a dose dependence?. in Toxicology Letters. 2016;259(Supplement):S170-S171.
doi:10.1016/j.toxlet.2016.07.727 .

Buha, Aleksandra, Powell, J.J, Jugdaohsingh, R., Matović, Vesna, "Damaging cadmium actions in bone tissue-is there a dose dependence?" in Toxicology Letters, 259, no. Supplement (2016):S170-S171,
https://doi.org/10.1016/j.toxlet.2016.07.727 . .

TY  - CONF
AU  - Ćurčić, Marijana
AU  - Buha, Aleksandra
AU  - Milovanović, V.
AU  - Antunović, M.
AU  - Đorđević, S.
AU  - Vučinić, Slavica
AU  - Đukić-Ćosić, Danijela
AU  - Bulat, Zorica
AU  - Matović, Vesna
AU  - Antonijević, Biljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2660
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium
VL  - 258
IS  - Supplement
SP  - S320
EP  - S320
DO  - 10.1016/j.toxlet.2016.06.2089
ER  - 

@conference{
author = "Ćurčić, Marijana and Buha, Aleksandra and Milovanović, V. and Antunović, M. and Đorđević, S. and Vučinić, Slavica and Đukić-Ćosić, Danijela and Bulat, Zorica and Matović, Vesna and Antonijević, Biljana",
year = "2016",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium",
volume = "258",
number = "Supplement",
pages = "S320-S320",
doi = "10.1016/j.toxlet.2016.06.2089"
}

Ćurčić, M., Buha, A., Milovanović, V., Antunović, M., Đorđević, S., Vučinić, S., Đukić-Ćosić, D., Bulat, Z., Matović, V.,& Antonijević, B.. (2016). Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 258(Supplement), S320-S320.
https://doi.org/10.1016/j.toxlet.2016.06.2089

Ćurčić M, Buha A, Milovanović V, Antunović M, Đorđević S, Vučinić S, Đukić-Ćosić D, Bulat Z, Matović V, Antonijević B. Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium. in Toxicology Letters. 2016;258(Supplement):S320-S320.
doi:10.1016/j.toxlet.2016.06.2089 .

Ćurčić, Marijana, Buha, Aleksandra, Milovanović, V., Antunović, M., Đorđević, S., Vučinić, Slavica, Đukić-Ćosić, Danijela, Bulat, Zorica, Matović, Vesna, Antonijević, Biljana, "Influence of decabrominated diphenyl ether on oxidative stress in brain caused by cadmium" in Toxicology Letters, 258, no. Supplement (2016):S320-S320,
https://doi.org/10.1016/j.toxlet.2016.06.2089 . .

TY  - JOUR
AU  - Ćurčić, Marijana
AU  - Ljubičić, Žaklina
AU  - Vuković, Gorica
AU  - Antonijević, Biljana
AU  - Bulat, Zorica
AU  - Matović, Vesna
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2703
AB  - In analytical methods used for monitoring of what special attention is paid to sample preparation. Therefore, the objective of this study was testing the efficiency of immunoaffinity columns (IAC) that are based on solid phase extraction principles used for samples preparation in determining aflatoxins and ochratoxins. Aflatoxins and ochratoxins concentrations were determined in totally 56 samples of food items: wheat, corn, rice, barley and other grains (19 samples), flour and flour products from grain and additives for the bakery industry (7 samples), fruits and vegetables (3 samples), hazelnut, walnut, almond, coconut flour (4 samples), roasted cocoa beans, peanuts, tea, coffee (16 samples), spices (4 samples) and meat and meat products (4 samples). Obtained results indicate advantage of IAC use for sample preparation based on enhanced specificity due to binding of extracted molecules to incorporated specific antibodies and rinsing the rest molecules from sample which could interfere with further analysis. Additional advantage is the usage of small amount of organic solvents and consequently decreased exposure of staff who conduct micotoxins determination. Of special interest is increase in method sensitivity since limit of quantification for aflatoxins and ochratoxins determination method is lower than maximal allowed concentration of these toxines prescribed by national rule book.
AB  - U analitičkim metodama koje se koriste u monitoringu posebna pažnja se pridaje pripremi uzorka, pa je i cilj ovog rada ispitivanje efikasnosti primene imunoafinitetnih kolona (IAC) za pripremu uzoraka kod određivanja aflatoksina i ohratoksina koje se zasnivaju na principu tečnočvrste ekstrakcije. Koncentracija aflatoksina i ohratoksina određivana je u ukupno 56 uzoraka različitih namirnica: pšenica, kukuruz, pirinač, ječam i ostala žita (19 uzoraka), brašno i proizvodi od brašna od žita i dodaci za pekarsku industriju (7 uzoraka), voće i povrće (3 uzorka), lešnik, orah, badem, brašno od kokosa (4 uzorka), prženi kakaovac, kikiriki, čajevi, kafa (16 uzoraka), začini (4 uzorka) i meso i proizvodi od mesa (4 uzorka). Dobijeni rezultati ukazuju na prednost primene IAC kolona u pripremi uzoraka, prvenstveno je postignuto povećanje specifičnosti metode usled vezivanja ekstrahovanih analita za inkorporirana specifična antitela i ispiranje ostalih komponenti uzorka, koje mogu ometati dalju analizu. Prednost je generisanje male količine otpadnih organskih rastvarača i smanjenje izloženosti osoblja koje izvodi metodu hromatografskog određivanja mikotoksina. Posebno je od značaja postignuto povećanje osetljivosti metode jer je postignuto da kvantifikacioni limiti za određivanje aflatoksina i ohratoksina budu znatno niži od maksimalno dozvoljenih koncentracija ovih jedinjenja propisanih nacionalnim pravilnikom.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Application of immunoaffinity columns for different food item samples preparation in micotoxins determination
T1  - Primena imunoafinitetnih kolona u pripremi različitih uzoraka namirnica za određivanje mikotoksina
VL  - 66
IS  - 4
SP  - 174
EP  - 182
DO  - 10.5937/arhfarm1604174C
ER  - 

@article{
author = "Ćurčić, Marijana and Ljubičić, Žaklina and Vuković, Gorica and Antonijević, Biljana and Bulat, Zorica and Matović, Vesna",
year = "2016",
abstract = "In analytical methods used for monitoring of what special attention is paid to sample preparation. Therefore, the objective of this study was testing the efficiency of immunoaffinity columns (IAC) that are based on solid phase extraction principles used for samples preparation in determining aflatoxins and ochratoxins. Aflatoxins and ochratoxins concentrations were determined in totally 56 samples of food items: wheat, corn, rice, barley and other grains (19 samples), flour and flour products from grain and additives for the bakery industry (7 samples), fruits and vegetables (3 samples), hazelnut, walnut, almond, coconut flour (4 samples), roasted cocoa beans, peanuts, tea, coffee (16 samples), spices (4 samples) and meat and meat products (4 samples). Obtained results indicate advantage of IAC use for sample preparation based on enhanced specificity due to binding of extracted molecules to incorporated specific antibodies and rinsing the rest molecules from sample which could interfere with further analysis. Additional advantage is the usage of small amount of organic solvents and consequently decreased exposure of staff who conduct micotoxins determination. Of special interest is increase in method sensitivity since limit of quantification for aflatoxins and ochratoxins determination method is lower than maximal allowed concentration of these toxines prescribed by national rule book., U analitičkim metodama koje se koriste u monitoringu posebna pažnja se pridaje pripremi uzorka, pa je i cilj ovog rada ispitivanje efikasnosti primene imunoafinitetnih kolona (IAC) za pripremu uzoraka kod određivanja aflatoksina i ohratoksina koje se zasnivaju na principu tečnočvrste ekstrakcije. Koncentracija aflatoksina i ohratoksina određivana je u ukupno 56 uzoraka različitih namirnica: pšenica, kukuruz, pirinač, ječam i ostala žita (19 uzoraka), brašno i proizvodi od brašna od žita i dodaci za pekarsku industriju (7 uzoraka), voće i povrće (3 uzorka), lešnik, orah, badem, brašno od kokosa (4 uzorka), prženi kakaovac, kikiriki, čajevi, kafa (16 uzoraka), začini (4 uzorka) i meso i proizvodi od mesa (4 uzorka). Dobijeni rezultati ukazuju na prednost primene IAC kolona u pripremi uzoraka, prvenstveno je postignuto povećanje specifičnosti metode usled vezivanja ekstrahovanih analita za inkorporirana specifična antitela i ispiranje ostalih komponenti uzorka, koje mogu ometati dalju analizu. Prednost je generisanje male količine otpadnih organskih rastvarača i smanjenje izloženosti osoblja koje izvodi metodu hromatografskog određivanja mikotoksina. Posebno je od značaja postignuto povećanje osetljivosti metode jer je postignuto da kvantifikacioni limiti za određivanje aflatoksina i ohratoksina budu znatno niži od maksimalno dozvoljenih koncentracija ovih jedinjenja propisanih nacionalnim pravilnikom.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Application of immunoaffinity columns for different food item samples preparation in micotoxins determination, Primena imunoafinitetnih kolona u pripremi različitih uzoraka namirnica za određivanje mikotoksina",
volume = "66",
number = "4",
pages = "174-182",
doi = "10.5937/arhfarm1604174C"
}

Ćurčić, M., Ljubičić, Ž., Vuković, G., Antonijević, B., Bulat, Z.,& Matović, V.. (2016). Application of immunoaffinity columns for different food item samples preparation in micotoxins determination. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 66(4), 174-182.
https://doi.org/10.5937/arhfarm1604174C

Ćurčić M, Ljubičić Ž, Vuković G, Antonijević B, Bulat Z, Matović V. Application of immunoaffinity columns for different food item samples preparation in micotoxins determination. in Arhiv za farmaciju. 2016;66(4):174-182.
doi:10.5937/arhfarm1604174C .

Ćurčić, Marijana, Ljubičić, Žaklina, Vuković, Gorica, Antonijević, Biljana, Bulat, Zorica, Matović, Vesna, "Application of immunoaffinity columns for different food item samples preparation in micotoxins determination" in Arhiv za farmaciju, 66, no. 4 (2016):174-182,
https://doi.org/10.5937/arhfarm1604174C . .

TY  - CONF
AU  - Buha, Aleksandra
AU  - Milovanović, Vesna
AU  - Antonijević, Biljana
AU  - Ćurčić, Marijana
AU  - Lukić, V.
AU  - Matović, Vesna
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2363
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Prolonged PCBs and Cd co-exposure and hepatic GSH levels in liver of rats: Is the combined effect additive, synergistic or antagonistic?
VL  - 238
IS  - 2, Supplement
SP  - S353
EP  - S353
DO  - 10.1016/j.toxlet.2015.08.1008
ER  - 

@conference{
author = "Buha, Aleksandra and Milovanović, Vesna and Antonijević, Biljana and Ćurčić, Marijana and Lukić, V. and Matović, Vesna",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Prolonged PCBs and Cd co-exposure and hepatic GSH levels in liver of rats: Is the combined effect additive, synergistic or antagonistic?",
volume = "238",
number = "2, Supplement",
pages = "S353-S353",
doi = "10.1016/j.toxlet.2015.08.1008"
}

Buha, A., Milovanović, V., Antonijević, B., Ćurčić, M., Lukić, V.,& Matović, V.. (2015). Prolonged PCBs and Cd co-exposure and hepatic GSH levels in liver of rats: Is the combined effect additive, synergistic or antagonistic?. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S353-S353.
https://doi.org/10.1016/j.toxlet.2015.08.1008

Buha A, Milovanović V, Antonijević B, Ćurčić M, Lukić V, Matović V. Prolonged PCBs and Cd co-exposure and hepatic GSH levels in liver of rats: Is the combined effect additive, synergistic or antagonistic?. in Toxicology Letters. 2015;238(2, Supplement):S353-S353.
doi:10.1016/j.toxlet.2015.08.1008 .

Buha, Aleksandra, Milovanović, Vesna, Antonijević, Biljana, Ćurčić, Marijana, Lukić, V., Matović, Vesna, "Prolonged PCBs and Cd co-exposure and hepatic GSH levels in liver of rats: Is the combined effect additive, synergistic or antagonistic?" in Toxicology Letters, 238, no. 2, Supplement (2015):S353-S353,
https://doi.org/10.1016/j.toxlet.2015.08.1008 . .

TY  - CONF
AU  - Milovanović, V.
AU  - Buha, Aleksandra
AU  - Matović, Vesna
AU  - Ćurčić, Marijana
AU  - Vučinić, Slavica
AU  - Antonijević, Biljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2372
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Correlation of total and free thyroid hormones in rats after subacute exposure to decabrominated diphenyl ether
VL  - 238
IS  - 2, Supplement
SP  - S266
EP  - S266
DO  - 10.1016/j.toxlet.2015.08.768
ER  - 

@conference{
author = "Milovanović, V. and Buha, Aleksandra and Matović, Vesna and Ćurčić, Marijana and Vučinić, Slavica and Antonijević, Biljana",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Correlation of total and free thyroid hormones in rats after subacute exposure to decabrominated diphenyl ether",
volume = "238",
number = "2, Supplement",
pages = "S266-S266",
doi = "10.1016/j.toxlet.2015.08.768"
}

Milovanović, V., Buha, A., Matović, V., Ćurčić, M., Vučinić, S.,& Antonijević, B.. (2015). Correlation of total and free thyroid hormones in rats after subacute exposure to decabrominated diphenyl ether. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S266-S266.
https://doi.org/10.1016/j.toxlet.2015.08.768

Milovanović V, Buha A, Matović V, Ćurčić M, Vučinić S, Antonijević B. Correlation of total and free thyroid hormones in rats after subacute exposure to decabrominated diphenyl ether. in Toxicology Letters. 2015;238(2, Supplement):S266-S266.
doi:10.1016/j.toxlet.2015.08.768 .

Milovanović, V., Buha, Aleksandra, Matović, Vesna, Ćurčić, Marijana, Vučinić, Slavica, Antonijević, Biljana, "Correlation of total and free thyroid hormones in rats after subacute exposure to decabrominated diphenyl ether" in Toxicology Letters, 238, no. 2, Supplement (2015):S266-S266,
https://doi.org/10.1016/j.toxlet.2015.08.768 . .

TY  - CONF
AU  - Đukić-Ćosić, Danijela
AU  - Buha, Aleksandra
AU  - Bulat, Zorica
AU  - Ugarković, A.
AU  - Berta, V.
AU  - Repić, A.
AU  - Antonijević, Biljana
AU  - Matović, Vesna
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2370
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Assessment of cadmium intake from commercial products based on herb St. Johns wort (Hypericum perforatum L.)
VL  - 238
IS  - 2, Supplement
SP  - S130
EP  - S130
DO  - 10.1016/j.toxlet.2015.08.409
ER  - 

@conference{
author = "Đukić-Ćosić, Danijela and Buha, Aleksandra and Bulat, Zorica and Ugarković, A. and Berta, V. and Repić, A. and Antonijević, Biljana and Matović, Vesna",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Assessment of cadmium intake from commercial products based on herb St. Johns wort (Hypericum perforatum L.)",
volume = "238",
number = "2, Supplement",
pages = "S130-S130",
doi = "10.1016/j.toxlet.2015.08.409"
}

Đukić-Ćosić, D., Buha, A., Bulat, Z., Ugarković, A., Berta, V., Repić, A., Antonijević, B.,& Matović, V.. (2015). Assessment of cadmium intake from commercial products based on herb St. Johns wort (Hypericum perforatum L.). in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S130-S130.
https://doi.org/10.1016/j.toxlet.2015.08.409

Đukić-Ćosić D, Buha A, Bulat Z, Ugarković A, Berta V, Repić A, Antonijević B, Matović V. Assessment of cadmium intake from commercial products based on herb St. Johns wort (Hypericum perforatum L.). in Toxicology Letters. 2015;238(2, Supplement):S130-S130.
doi:10.1016/j.toxlet.2015.08.409 .

Đukić-Ćosić, Danijela, Buha, Aleksandra, Bulat, Zorica, Ugarković, A., Berta, V., Repić, A., Antonijević, Biljana, Matović, Vesna, "Assessment of cadmium intake from commercial products based on herb St. Johns wort (Hypericum perforatum L.)" in Toxicology Letters, 238, no. 2, Supplement (2015):S130-S130,
https://doi.org/10.1016/j.toxlet.2015.08.409 . .

TY  - CONF
AU  - Buha, Aleksandra
AU  - Milovanović, Vesna
AU  - Nikolić, Dragica
AU  - Đukić-Ćosić, Danijela
AU  - Vukomanović, Predrag
AU  - Matović, Vesna
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2368
PB  - Elsevier Ireland Ltd, Clare
C3  - Toxicology Letters
T1  - Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats
VL  - 238
IS  - 2, Supplement
SP  - S123
EP  - S124
DO  - 10.1016/j.toxlet.2015.08.393
ER  - 

@conference{
author = "Buha, Aleksandra and Milovanović, Vesna and Nikolić, Dragica and Đukić-Ćosić, Danijela and Vukomanović, Predrag and Matović, Vesna",
year = "2015",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Toxicology Letters",
title = "Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats",
volume = "238",
number = "2, Supplement",
pages = "S123-S124",
doi = "10.1016/j.toxlet.2015.08.393"
}

Buha, A., Milovanović, V., Nikolić, D., Đukić-Ćosić, D., Vukomanović, P.,& Matović, V.. (2015). Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats. in Toxicology Letters
Elsevier Ireland Ltd, Clare., 238(2, Supplement), S123-S124.
https://doi.org/10.1016/j.toxlet.2015.08.393

Buha A, Milovanović V, Nikolić D, Đukić-Ćosić D, Vukomanović P, Matović V. Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats. in Toxicology Letters. 2015;238(2, Supplement):S123-S124.
doi:10.1016/j.toxlet.2015.08.393 .

Buha, Aleksandra, Milovanović, Vesna, Nikolić, Dragica, Đukić-Ćosić, Danijela, Vukomanović, Predrag, Matović, Vesna, "Dose dependence of Cd effects of antioxidant defense system in liver of subacutely exposed rats" in Toxicology Letters, 238, no. 2, Supplement (2015):S123-S124,
https://doi.org/10.1016/j.toxlet.2015.08.393 . .