TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Vukelić, Jana
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/895
AB  - A pulse perturbation technique was applied to the Bray-Liebhafsky (BL) oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point, to determine micro-quantitatively 6-O-acetylmorphine (6-O-AM). The proposed method, in optimized reaction conditions ([KIO3](0) = 5.9 x 10(-2) M, [H2SO4](0) = 5.5 x 10(-2) M, and [H2O2](0) = 2.0 x 10(-1) M, j(o) = 2.95 x 10(-2) min(-1), and T = 42.9 degrees C), relied on the linear relationship between maximal potential shift, Delta E-m, caused by perturbation, and the logarithm of the amount of 6-O-acetylmorphine. The method had a rather good sample throughput of 40 samples h(-1) with the sensitivity determined to be 0.9 mu g mL(-1) and the precision RSD = 1.8%. The proposed method was successfully applied to the quantitative determination of 6-O-AM in a real seized street drug sample. The obtained result agrees with those obtained by HPLC. There was no interference from structurally related and associated compounds, such as papaverin, noscapin, and heroin.
PB  - Chemical Soc Japan, Tokyo
T2  - Bulletin of the Chemical Society of Japan
T1  - Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples
VL  - 80
IS  - 10
SP  - 1942
EP  - 1948
DO  - 10.1246/bcsj.80.1942
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Vukelić, Jana and Kolar-Anić, Ljiljana and Anić, Slobodan",
year = "2007",
abstract = "A pulse perturbation technique was applied to the Bray-Liebhafsky (BL) oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point, to determine micro-quantitatively 6-O-acetylmorphine (6-O-AM). The proposed method, in optimized reaction conditions ([KIO3](0) = 5.9 x 10(-2) M, [H2SO4](0) = 5.5 x 10(-2) M, and [H2O2](0) = 2.0 x 10(-1) M, j(o) = 2.95 x 10(-2) min(-1), and T = 42.9 degrees C), relied on the linear relationship between maximal potential shift, Delta E-m, caused by perturbation, and the logarithm of the amount of 6-O-acetylmorphine. The method had a rather good sample throughput of 40 samples h(-1) with the sensitivity determined to be 0.9 mu g mL(-1) and the precision RSD = 1.8%. The proposed method was successfully applied to the quantitative determination of 6-O-AM in a real seized street drug sample. The obtained result agrees with those obtained by HPLC. There was no interference from structurally related and associated compounds, such as papaverin, noscapin, and heroin.",
publisher = "Chemical Soc Japan, Tokyo",
journal = "Bulletin of the Chemical Society of Japan",
title = "Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples",
volume = "80",
number = "10",
pages = "1942-1948",
doi = "10.1246/bcsj.80.1942"
}

Pejić, N., Blagojević, S., Vukelić, J., Kolar-Anić, L.,& Anić, S.. (2007). Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples. in Bulletin of the Chemical Society of Japan
Chemical Soc Japan, Tokyo., 80(10), 1942-1948.
https://doi.org/10.1246/bcsj.80.1942

Pejić N, Blagojević S, Vukelić J, Kolar-Anić L, Anić S. Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples. in Bulletin of the Chemical Society of Japan. 2007;80(10):1942-1948.
doi:10.1246/bcsj.80.1942 .

Pejić, Nataša, Blagojević, Slavica, Vukelić, Jana, Kolar-Anić, Ljiljana, Anić, Slobodan, "Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples" in Bulletin of the Chemical Society of Japan, 80, no. 10 (2007):1942-1948,
https://doi.org/10.1246/bcsj.80.1942 . .