TY  - JOUR
AU  - Baralić, Ivana
AU  - Anđelković, Marija
AU  - Đorđević, Brižita
AU  - Dikić, Nenad
AU  - Radivojević, Nenad
AU  - Suzin-Živković, Violeta
AU  - Radojević-Skodrić, Sanja
AU  - Pejić, Snežana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2445
AB  - The physiologic stress induced by physical activity is reflected in immune systemperturbations, oxidative stress, muscle injury, and inflammation. We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts. Forty trained male soccer players were randomly assigned to Asx and placebo groups. Asx group was supplemented with 4mg of Asx. Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions. We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance. The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training. The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx. This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training. Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.
PB  - Hindawi Publishing Corp, New York
T2  - Evidence-Based Complementary and Alternative Medicine
T1  - Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players
DO  - 10.1155/2015/783761
ER  - 

@article{
author = "Baralić, Ivana and Anđelković, Marija and Đorđević, Brižita and Dikić, Nenad and Radivojević, Nenad and Suzin-Živković, Violeta and Radojević-Skodrić, Sanja and Pejić, Snežana",
year = "2015",
abstract = "The physiologic stress induced by physical activity is reflected in immune systemperturbations, oxidative stress, muscle injury, and inflammation. We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts. Forty trained male soccer players were randomly assigned to Asx and placebo groups. Asx group was supplemented with 4mg of Asx. Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions. We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance. The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training. The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx. This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training. Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.",
publisher = "Hindawi Publishing Corp, New York",
journal = "Evidence-Based Complementary and Alternative Medicine",
title = "Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players",
doi = "10.1155/2015/783761"
}

Baralić, I., Anđelković, M., Đorđević, B., Dikić, N., Radivojević, N., Suzin-Živković, V., Radojević-Skodrić, S.,& Pejić, S.. (2015). Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. in Evidence-Based Complementary and Alternative Medicine
Hindawi Publishing Corp, New York..
https://doi.org/10.1155/2015/783761

Baralić I, Anđelković M, Đorđević B, Dikić N, Radivojević N, Suzin-Živković V, Radojević-Skodrić S, Pejić S. Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. in Evidence-Based Complementary and Alternative Medicine. 2015;.
doi:10.1155/2015/783761 .

Baralić, Ivana, Anđelković, Marija, Đorđević, Brižita, Dikić, Nenad, Radivojević, Nenad, Suzin-Živković, Violeta, Radojević-Skodrić, Sanja, Pejić, Snežana, "Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players" in Evidence-Based Complementary and Alternative Medicine (2015),
https://doi.org/10.1155/2015/783761 . .