TY  - JOUR
AU  - Rizzo, Manfredi
AU  - Kotur-Stevuljević, Jelena
AU  - Berneis, Kaspar
AU  - Spinas, Giatgen
AU  - Rini, Giovam Battista
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Vekić, Jelena
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1228
AB  - Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with antioxidants might reduce vascular events. Oxidative modifications of low-density lipoproteins (LDL) represent an early stage of atherosclerosis, and small, dense LDL are more susceptible to oxidation than larger, more buoyant particles. Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis. Recent studies suggested that novel therapeutic strategies may take into account the removal of such particles from circulation. Future research is required to explore the potential synergistic impact of markers of oxidative stress and atherogenic dyslipidemia, particularly small dense LDL, on cardiovascular risk. (Translational Research 2009; 153:217-223)
PB  - Elsevier Science Inc, New York
T2  - Transplant International
T1  - Atherogenic dyslipidemia and oxidative stress: a new look
VL  - 153
IS  - 5
SP  - 217
EP  - 223
DO  - 10.1016/j.trsl.2009.01.008
ER  - 

@article{
author = "Rizzo, Manfredi and Kotur-Stevuljević, Jelena and Berneis, Kaspar and Spinas, Giatgen and Rini, Giovam Battista and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Vekić, Jelena",
year = "2009",
abstract = "Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with antioxidants might reduce vascular events. Oxidative modifications of low-density lipoproteins (LDL) represent an early stage of atherosclerosis, and small, dense LDL are more susceptible to oxidation than larger, more buoyant particles. Oxidized LDL are independent predictors of subclinical and clinical atherosclerosis. Recent studies suggested that novel therapeutic strategies may take into account the removal of such particles from circulation. Future research is required to explore the potential synergistic impact of markers of oxidative stress and atherogenic dyslipidemia, particularly small dense LDL, on cardiovascular risk. (Translational Research 2009; 153:217-223)",
publisher = "Elsevier Science Inc, New York",
journal = "Transplant International",
title = "Atherogenic dyslipidemia and oxidative stress: a new look",
volume = "153",
number = "5",
pages = "217-223",
doi = "10.1016/j.trsl.2009.01.008"
}

Rizzo, M., Kotur-Stevuljević, J., Berneis, K., Spinas, G., Rini, G. B., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V.,& Vekić, J.. (2009). Atherogenic dyslipidemia and oxidative stress: a new look. in Transplant International
Elsevier Science Inc, New York., 153(5), 217-223.
https://doi.org/10.1016/j.trsl.2009.01.008

Rizzo M, Kotur-Stevuljević J, Berneis K, Spinas G, Rini GB, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Vekić J. Atherogenic dyslipidemia and oxidative stress: a new look. in Transplant International. 2009;153(5):217-223.
doi:10.1016/j.trsl.2009.01.008 .

Rizzo, Manfredi, Kotur-Stevuljević, Jelena, Berneis, Kaspar, Spinas, Giatgen, Rini, Giovam Battista, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Vekić, Jelena, "Atherogenic dyslipidemia and oxidative stress: a new look" in Transplant International, 153, no. 5 (2009):217-223,
https://doi.org/10.1016/j.trsl.2009.01.008 . .

TY  - JOUR
AU  - Rizzo, Manfredi
AU  - Berneis, Kaspar
AU  - Zeljković, Aleksandra
AU  - Vekić, Jelena
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1190
AB  - Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) plasma populations are composed of heterogeneous subfractions that are different in size, density and protein/lipid content. There is increasing evidence that small, dense LDL particles are strongly associated with higher cardiovascular disease risk. Similarly, several studies have investigated whether smaller HDL particles are more protective than their larger counterparts and more recent findings suggest that small, dense HDL has significantly higher atheroprotective activity than larger L HDL. Yet, certain impairments of the protein/lipid content in small, dense HDL may decrease its antiatherogenic capacity or even induce pro-atherogenic properties. Therefore, it seems that the small, dense phenomenon applies to both LDL and HDL particles. Measurement of LDL and HDL cholesterol concentrations has proven clinical utility, while the usefulness of LDL and HDL subclasses determination in clinical practice offers grounds for further exploration. However, LDL and HDL particles characterisation requires either special equipment or a lengthy analytical time and is, therefore, still unsuitable for general clinical use. It remains to be established whether lipoprotein subclasses should be analyzed in routine practice, although their assessment in high-risk subjects could be recommended. (Clin. Lab. 2009;55:421-429)
PB  - Clin Lab Publ, Heidelberg
T2  - Clinical Laboratory
T1  - Should we routinely measure low-density and high-density lipoprotein subclasses?
VL  - 55
IS  - 11-12
SP  - 421
EP  - 429
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1190
ER  - 

@article{
author = "Rizzo, Manfredi and Berneis, Kaspar and Zeljković, Aleksandra and Vekić, Jelena",
year = "2009",
abstract = "Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) plasma populations are composed of heterogeneous subfractions that are different in size, density and protein/lipid content. There is increasing evidence that small, dense LDL particles are strongly associated with higher cardiovascular disease risk. Similarly, several studies have investigated whether smaller HDL particles are more protective than their larger counterparts and more recent findings suggest that small, dense HDL has significantly higher atheroprotective activity than larger L HDL. Yet, certain impairments of the protein/lipid content in small, dense HDL may decrease its antiatherogenic capacity or even induce pro-atherogenic properties. Therefore, it seems that the small, dense phenomenon applies to both LDL and HDL particles. Measurement of LDL and HDL cholesterol concentrations has proven clinical utility, while the usefulness of LDL and HDL subclasses determination in clinical practice offers grounds for further exploration. However, LDL and HDL particles characterisation requires either special equipment or a lengthy analytical time and is, therefore, still unsuitable for general clinical use. It remains to be established whether lipoprotein subclasses should be analyzed in routine practice, although their assessment in high-risk subjects could be recommended. (Clin. Lab. 2009;55:421-429)",
publisher = "Clin Lab Publ, Heidelberg",
journal = "Clinical Laboratory",
title = "Should we routinely measure low-density and high-density lipoprotein subclasses?",
volume = "55",
number = "11-12",
pages = "421-429",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1190"
}

Rizzo, M., Berneis, K., Zeljković, A.,& Vekić, J.. (2009). Should we routinely measure low-density and high-density lipoprotein subclasses?. in Clinical Laboratory
Clin Lab Publ, Heidelberg., 55(11-12), 421-429.
https://hdl.handle.net/21.15107/rcub_farfar_1190

Rizzo M, Berneis K, Zeljković A, Vekić J. Should we routinely measure low-density and high-density lipoprotein subclasses?. in Clinical Laboratory. 2009;55(11-12):421-429.
https://hdl.handle.net/21.15107/rcub_farfar_1190 .

Rizzo, Manfredi, Berneis, Kaspar, Zeljković, Aleksandra, Vekić, Jelena, "Should we routinely measure low-density and high-density lipoprotein subclasses?" in Clinical Laboratory, 55, no. 11-12 (2009):421-429,
https://hdl.handle.net/21.15107/rcub_farfar_1190 .