TY  - JOUR
AU  - Cirković, Ivana
AU  - Jocić, Dario
AU  - Božić, Dragana
AU  - Đukić, Slobodanka
AU  - Konstantinović, Neda
AU  - Radak, Đorđe
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3225
AB  - Biofilm-associated wound infections are a major global health issue, and methicillin-resistant Staphylococcus aureus (MRSA) is among the greatest therapeutic challenges. Vacuum-assisted closure (VAC) therapy is now being revisited as an alternative treatment for both acute and chronic wounds. However, data supporting the concept of its antibiofilm effect remain limited. Using quantitative biofilm-forming assay and a range of genotypic methods (spa, SCCmec, and agr typing), study authors showed that VAC therapy can significantly prevent biofilm formation (P  lt  .01) of a range of MRSA wound isolates differing widely in their biofilm-forming abilities and genetic background. The best effect was presented on CC5-MRSA-SCCmecI-agrII, a dominant MRSA clone among wound isolates worldwide. An assessment of effects of different protocols on dressing changes (1 or 2 times per week) demonstrated significantly greater antibiofilm activity (P  lt  .05) of 3-day dressing changes. These findings support the use of VAC therapy as a topical antibiofilm treatment for the effective management of wound healing.
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Advances in Skin & Wound Care
T1  - The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms
VL  - 31
IS  - 8
SP  - 361
EP  - 364
DO  - 10.1097/01.ASW.0000540070.07040.70
ER  - 

@article{
author = "Cirković, Ivana and Jocić, Dario and Božić, Dragana and Đukić, Slobodanka and Konstantinović, Neda and Radak, Đorđe",
year = "2018",
abstract = "Biofilm-associated wound infections are a major global health issue, and methicillin-resistant Staphylococcus aureus (MRSA) is among the greatest therapeutic challenges. Vacuum-assisted closure (VAC) therapy is now being revisited as an alternative treatment for both acute and chronic wounds. However, data supporting the concept of its antibiofilm effect remain limited. Using quantitative biofilm-forming assay and a range of genotypic methods (spa, SCCmec, and agr typing), study authors showed that VAC therapy can significantly prevent biofilm formation (P  lt  .01) of a range of MRSA wound isolates differing widely in their biofilm-forming abilities and genetic background. The best effect was presented on CC5-MRSA-SCCmecI-agrII, a dominant MRSA clone among wound isolates worldwide. An assessment of effects of different protocols on dressing changes (1 or 2 times per week) demonstrated significantly greater antibiofilm activity (P  lt  .05) of 3-day dressing changes. These findings support the use of VAC therapy as a topical antibiofilm treatment for the effective management of wound healing.",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Advances in Skin & Wound Care",
title = "The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms",
volume = "31",
number = "8",
pages = "361-364",
doi = "10.1097/01.ASW.0000540070.07040.70"
}

Cirković, I., Jocić, D., Božić, D., Đukić, S., Konstantinović, N.,& Radak, Đ.. (2018). The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms. in Advances in Skin & Wound Care
Lippincott Williams & Wilkins, Philadelphia., 31(8), 361-364.
https://doi.org/10.1097/01.ASW.0000540070.07040.70

Cirković I, Jocić D, Božić D, Đukić S, Konstantinović N, Radak Đ. The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms. in Advances in Skin & Wound Care. 2018;31(8):361-364.
doi:10.1097/01.ASW.0000540070.07040.70 .

Cirković, Ivana, Jocić, Dario, Božić, Dragana, Đukić, Slobodanka, Konstantinović, Neda, Radak, Đorđe, "The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms" in Advances in Skin & Wound Care, 31, no. 8 (2018):361-364,
https://doi.org/10.1097/01.ASW.0000540070.07040.70 . .

TY  - JOUR
AU  - Konstantinović, Neda
AU  - Cirković, Ivana
AU  - Dukić, Slobodanka
AU  - Marić, Vesna
AU  - Božić, Dragana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2786
AB  - Achromobacter spp. may contaminate lenses, lens cases, and contact lens solutions and cause ocular infections. The aim of this study was to investigate the possibility of isolated strain of Achromobacter xylosoxidans to form biofilm on the surface of soft contact lenses (CL), to quantify the production of the formed biofilm, and compare it with the reference strains (Pseudomonas aeruginosa, Staphylococcus aureus, and Haemophilus influenzae). Bacterial strain isolated from one contact lens case was identified as A. xylosoxidans using Vitek2 Automated System. Biofilm forming capacity of isolated strain of A. xylosoxidans and reference strains of P. aeruginosa, S. aureus, and H. influenzae on soft CL were analyzed by commonly used microtitre plate method. Our results showed that isolated strain of A. xylosoxidans was capable to form biofilm on the surface of soft contact lens. A. xylosoxidans was strong biofilm producer while all examined reference strains were moderate biofilm producers. A. xylosoxidans appears to be superior biofilm producer on soft CL compared to reference strains.
PB  - Akademiai Kiado Rt, Budapest
T2  - Acta Microbiologica et Immunologica Hungarica
T1  - Biofilm formation of achromobacter xylosoxidans on contact lens
VL  - 64
IS  - 3
SP  - 293
EP  - 300
DO  - 10.1556/030.64.2017.005
ER  - 

@article{
author = "Konstantinović, Neda and Cirković, Ivana and Dukić, Slobodanka and Marić, Vesna and Božić, Dragana",
year = "2017",
abstract = "Achromobacter spp. may contaminate lenses, lens cases, and contact lens solutions and cause ocular infections. The aim of this study was to investigate the possibility of isolated strain of Achromobacter xylosoxidans to form biofilm on the surface of soft contact lenses (CL), to quantify the production of the formed biofilm, and compare it with the reference strains (Pseudomonas aeruginosa, Staphylococcus aureus, and Haemophilus influenzae). Bacterial strain isolated from one contact lens case was identified as A. xylosoxidans using Vitek2 Automated System. Biofilm forming capacity of isolated strain of A. xylosoxidans and reference strains of P. aeruginosa, S. aureus, and H. influenzae on soft CL were analyzed by commonly used microtitre plate method. Our results showed that isolated strain of A. xylosoxidans was capable to form biofilm on the surface of soft contact lens. A. xylosoxidans was strong biofilm producer while all examined reference strains were moderate biofilm producers. A. xylosoxidans appears to be superior biofilm producer on soft CL compared to reference strains.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Acta Microbiologica et Immunologica Hungarica",
title = "Biofilm formation of achromobacter xylosoxidans on contact lens",
volume = "64",
number = "3",
pages = "293-300",
doi = "10.1556/030.64.2017.005"
}

Konstantinović, N., Cirković, I., Dukić, S., Marić, V.,& Božić, D.. (2017). Biofilm formation of achromobacter xylosoxidans on contact lens. in Acta Microbiologica et Immunologica Hungarica
Akademiai Kiado Rt, Budapest., 64(3), 293-300.
https://doi.org/10.1556/030.64.2017.005

Konstantinović N, Cirković I, Dukić S, Marić V, Božić D. Biofilm formation of achromobacter xylosoxidans on contact lens. in Acta Microbiologica et Immunologica Hungarica. 2017;64(3):293-300.
doi:10.1556/030.64.2017.005 .

Konstantinović, Neda, Cirković, Ivana, Dukić, Slobodanka, Marić, Vesna, Božić, Dragana, "Biofilm formation of achromobacter xylosoxidans on contact lens" in Acta Microbiologica et Immunologica Hungarica, 64, no. 3 (2017):293-300,
https://doi.org/10.1556/030.64.2017.005 . .

TY  - JOUR
AU  - Pavlović, Bojan
AU  - Božić, Dragana
AU  - Milovanović, Jovica
AU  - Jotić, Ana
AU  - Đukić, Vojko
AU  - Đukić, Slobodanka
AU  - Konstantinović, Neda
AU  - Cirković, Ivana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2695
AB  - Objectives: Biofilms are associated with persistent infections and resistant to conventional therapeutic strategies. The aim of this study was to investigate the quantity of biofilm produced on silicone intranasal splints. Methods: Quantity of biofilm formation on silicone splints (SS) was tested on 15 strains of Staphylococcus aureus and Moraxella catarrhalis, respectively. Antimicrobial susceptibility testing was performed in accordance with European Committee on Antimicrobial Susceptibility Testing recommendations. Results: All tested strains formed different amounts of biofilm on SS: 66.7% S. aureus and 93.3% M. catarrhalis were weak biofilm producers and 33.3% S. aureus and 6.7% M. catarrhalis were moderate biofilm producers. S. aureus formed significantly higher quantity of biofilm compared with M. catarrhalis (p  lt  0.05). Multidrug resistant S. aureus produced significantly higher amount of biofilm compared with non-multidrug resistant strains (p  lt  0.05). Conclusion: Quantity of biofilm on SS is highly dependent on bacterial species and their resistance patterns. Future studies are needed to ascertain another therapeutic option for prophylaxis prior to SS placement.
PB  - Akademiai Kiado Rt, Budapest
T2  - Acta Microbiologica et Immunologica Hungarica
T1  - Quantification of biofilm formation on silicone intranasal splints: An in vitro study
VL  - 63
IS  - 3
SP  - 301
EP  - 311
DO  - 10.1556/030.63.2016.006
ER  - 

@article{
author = "Pavlović, Bojan and Božić, Dragana and Milovanović, Jovica and Jotić, Ana and Đukić, Vojko and Đukić, Slobodanka and Konstantinović, Neda and Cirković, Ivana",
year = "2016",
abstract = "Objectives: Biofilms are associated with persistent infections and resistant to conventional therapeutic strategies. The aim of this study was to investigate the quantity of biofilm produced on silicone intranasal splints. Methods: Quantity of biofilm formation on silicone splints (SS) was tested on 15 strains of Staphylococcus aureus and Moraxella catarrhalis, respectively. Antimicrobial susceptibility testing was performed in accordance with European Committee on Antimicrobial Susceptibility Testing recommendations. Results: All tested strains formed different amounts of biofilm on SS: 66.7% S. aureus and 93.3% M. catarrhalis were weak biofilm producers and 33.3% S. aureus and 6.7% M. catarrhalis were moderate biofilm producers. S. aureus formed significantly higher quantity of biofilm compared with M. catarrhalis (p  lt  0.05). Multidrug resistant S. aureus produced significantly higher amount of biofilm compared with non-multidrug resistant strains (p  lt  0.05). Conclusion: Quantity of biofilm on SS is highly dependent on bacterial species and their resistance patterns. Future studies are needed to ascertain another therapeutic option for prophylaxis prior to SS placement.",
publisher = "Akademiai Kiado Rt, Budapest",
journal = "Acta Microbiologica et Immunologica Hungarica",
title = "Quantification of biofilm formation on silicone intranasal splints: An in vitro study",
volume = "63",
number = "3",
pages = "301-311",
doi = "10.1556/030.63.2016.006"
}

Pavlović, B., Božić, D., Milovanović, J., Jotić, A., Đukić, V., Đukić, S., Konstantinović, N.,& Cirković, I.. (2016). Quantification of biofilm formation on silicone intranasal splints: An in vitro study. in Acta Microbiologica et Immunologica Hungarica
Akademiai Kiado Rt, Budapest., 63(3), 301-311.
https://doi.org/10.1556/030.63.2016.006

Pavlović B, Božić D, Milovanović J, Jotić A, Đukić V, Đukić S, Konstantinović N, Cirković I. Quantification of biofilm formation on silicone intranasal splints: An in vitro study. in Acta Microbiologica et Immunologica Hungarica. 2016;63(3):301-311.
doi:10.1556/030.63.2016.006 .

Pavlović, Bojan, Božić, Dragana, Milovanović, Jovica, Jotić, Ana, Đukić, Vojko, Đukić, Slobodanka, Konstantinović, Neda, Cirković, Ivana, "Quantification of biofilm formation on silicone intranasal splints: An in vitro study" in Acta Microbiologica et Immunologica Hungarica, 63, no. 3 (2016):301-311,
https://doi.org/10.1556/030.63.2016.006 . .