TY  - CONF
AU  - Ilić, Tijana
AU  - Krgović, Nemanja
AU  - Marčetić, Mirjana
AU  - Vidović, Bojana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5096
AB  - Due to the presence of many nutrients and bioactive compounds, fruits of Lycium species (Fructus Lycii, goji berries) are recognized as a “superfood,” which regular consumption might exert many beneficial health effects. Therefore, in addition to China and other Asian countries, the cultivation of Lycium species has become widespread throughout Europe. This study investigated the total phenolics (TPC), total flavonoids (TFC) and polysaccharides content, as well as biological properties of goji berry (Lycium barbarum L.) cultivated in the Belgrade region, Serbia. The HPLC method was used for the identification of individual phenolic compounds (rutin, quercetin-diglucuronide, chlorogenic acid and caffeic acid). Antioxidant properties of goji berry extracts with different solvent were evaluated for radical scavenging (DPPH, ABTS), reducing power (CUPRAC, FRAP), and β-carotene/linoleic acid bleaching inhibition capacity. Additionally, goji berry extracts were screened for their anti-diabetic (α-amylase, α-glucosidase), anti-tyrosinase, and anti-acetylcholinesterase activities. Methanol was identified as the most effective solvent for the extraction, resulting in the highest contents of TPC (3.76 mg GAE/g dry weight), TFC (0.65 mg CE/g dry weight), as well as superior antioxidant activity evaluated by all assays. Also, the methanol extract of goji berry inhibited all tested enzymes in concentration-dependent manners. The highest enzyme inhibitory activity was shown for tyrosinase (IC50 of 1.4 mg ± 0.01 mg/mL). The IC50 values were 4.66 ± 0.25 mg/mL, 10.68 ± 0.07 mg/mL, 7.07 ± 0.1 mg/mL for α-amylase, α-glucosidase and acetylcholinesterase inhibition activity, respectively. Overall, obtained results suggest that goji berry cultivated in Serbia is a valuable source of bioactive compounds that can be use in the food, nutraceutical, and cosmetic industries.
PB  - University of Belgrade
C3  - UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts
T1  - Phytochemical composition and in vitro biological activities of goji berry cultivated in Serbia
SP  - 110
EP  - 110
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5096
ER  - 

@conference{
author = "Ilić, Tijana and Krgović, Nemanja and Marčetić, Mirjana and Vidović, Bojana",
year = "2021",
abstract = "Due to the presence of many nutrients and bioactive compounds, fruits of Lycium species (Fructus Lycii, goji berries) are recognized as a “superfood,” which regular consumption might exert many beneficial health effects. Therefore, in addition to China and other Asian countries, the cultivation of Lycium species has become widespread throughout Europe. This study investigated the total phenolics (TPC), total flavonoids (TFC) and polysaccharides content, as well as biological properties of goji berry (Lycium barbarum L.) cultivated in the Belgrade region, Serbia. The HPLC method was used for the identification of individual phenolic compounds (rutin, quercetin-diglucuronide, chlorogenic acid and caffeic acid). Antioxidant properties of goji berry extracts with different solvent were evaluated for radical scavenging (DPPH, ABTS), reducing power (CUPRAC, FRAP), and β-carotene/linoleic acid bleaching inhibition capacity. Additionally, goji berry extracts were screened for their anti-diabetic (α-amylase, α-glucosidase), anti-tyrosinase, and anti-acetylcholinesterase activities. Methanol was identified as the most effective solvent for the extraction, resulting in the highest contents of TPC (3.76 mg GAE/g dry weight), TFC (0.65 mg CE/g dry weight), as well as superior antioxidant activity evaluated by all assays. Also, the methanol extract of goji berry inhibited all tested enzymes in concentration-dependent manners. The highest enzyme inhibitory activity was shown for tyrosinase (IC50 of 1.4 mg ± 0.01 mg/mL). The IC50 values were 4.66 ± 0.25 mg/mL, 10.68 ± 0.07 mg/mL, 7.07 ± 0.1 mg/mL for α-amylase, α-glucosidase and acetylcholinesterase inhibition activity, respectively. Overall, obtained results suggest that goji berry cultivated in Serbia is a valuable source of bioactive compounds that can be use in the food, nutraceutical, and cosmetic industries.",
publisher = "University of Belgrade",
journal = "UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts",
title = "Phytochemical composition and in vitro biological activities of goji berry cultivated in Serbia",
pages = "110-110",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5096"
}

Ilić, T., Krgović, N., Marčetić, M.,& Vidović, B.. (2021). Phytochemical composition and in vitro biological activities of goji berry cultivated in Serbia. in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts
University of Belgrade., 110-110.
https://hdl.handle.net/21.15107/rcub_farfar_5096

Ilić T, Krgović N, Marčetić M, Vidović B. Phytochemical composition and in vitro biological activities of goji berry cultivated in Serbia. in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts. 2021;:110-110.
https://hdl.handle.net/21.15107/rcub_farfar_5096 .

Ilić, Tijana, Krgović, Nemanja, Marčetić, Mirjana, Vidović, Bojana, "Phytochemical composition and in vitro biological activities of goji berry cultivated in Serbia" in UNIFOOD conference, Belgrade, September 24-25, 2021, Book of Abstracts (2021):110-110,
https://hdl.handle.net/21.15107/rcub_farfar_5096 .