TY  - JOUR
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5579
AB  - Abstract
Flavonoids, as plant-derived compounds, were essential active components in traditional
medicine for centuries. Their potential or confirmed effects include antiviral, antimutagenic, antiinflammatory, antibacterial, vasodilatory, and anticancer properties. The promotion of a plantbased diet, along with the benefits of consuming flavonoids, has recently become increasingly
attractive. 3-Hydroxyflavone (3HF) is the structural spine of flavonols, an important subgroup of
flavonoids. Although 3HF itself does not exist in plants per se, it exerts many of its effects because
of its characteristics that allow it to prevent free radical generation. This work is focused on the
characterization of 3HF complexes with zinc(II) and aluminium(III) ions (Zn-3HF and Al-3HF,
respectively). Besides this, a simple, fast, and low-priced spectrophotometric method for 3HF
determination, with very low LOD and LOQ, based on Zn-3HF and Al-3HF formation, was
established. A slight advantage is given to the modification with Al3+ ion on pH 4.91, due to very
low LOD and LOQ values of 1.83×10-7 molL-1
, and 5.50×10-7 molL-1
, respectively, and a high
correlation coefficient, R =0.99986. Furthermore, the antioxidant ability of Zn-3HF, Al-3HF, and
parent 3HF was examined by the ABTS and DPPH tests. They brought the Zn-3HF complex to
the fore as a potential antioxidative agent.
AB  - Flavonoidi, jedinjenja biljnog porekla, vekovima su bili veoma važne aktivne komponente u tradicionalnoj medicini. Veliki broj njihovih potencijalnih ili već potvrđenih efekata uključuje antivirusna, antimutagena, antiinflamatorna, antibakterijska, vazodilatatorna i antikancerogena svojstva. Promovisanje biljne ishrane, uz isticanje koristi konzumiranja flavonoida, u današnje vreme postalo je sve privlačnije. 3-Hidroksiflavon (3HF) je strukturni stub svih flavonola, važne klase flavonoida. Iako sam 3HF ne postoji u biljkama per se, on ispoljava mnoge svoje efekte zahvaljujući osobini da sprečava stvaranja slobodnih radikala. Ovaj rad je fokusiran na karakterizaciju kompleksa 3HF sa jonima cinka(II) i aluminijuma(III) (Zn-3HF i Al-3HF, respektivno). Izvršena je karakterizacija ovih kompleksa i razvijena brza i pristupačna metoda za spektrofotometrijsko određivanje 3HF, na osnovu formiranja kompleksa Zn-3HF i Al-3HF, sa veoma niskim vrednostima LOD i LOQ. Mala prednost je data modifikaciji sa Al3+ na pH 4,91 zbog izuzetno niskih vrednosti LOD i LOQ, 1,83×10-7 mol L-1 , odnosno 5,50×10-7 mol L-1 , kao i visokog koeficijenta korelacije, R=0,99986. Pored toga, antioksidativni kapaciteti sintetizovanih kompleksa Zn-3HF i Al-3HF, kao i samog 3HF, ispitani su DPPH i ABTS testovima i doveli su Zn-3HF kompleks u prvi plan za dalja ispitivanja kao potencijalnog antioksidativnog agensa.
PB  - Beograd : Savez farmaceutskih udruženja Srbije
T2  - Arhiv za farmaciju
T1  - Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles
T1  - Uporedno spektrofotometrijsko određivanje 3-hidroksiflavona bazirano na kompleksima cinka i aluminijuma i njihovi antioksidatni profili
VL  - 74
IS  - 1
SP  - 92
EP  - 104
DO  - 10.5937/arhfarm74-48637
ER  - 

@article{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana",
year = "2024",
abstract = "Abstract
Flavonoids, as plant-derived compounds, were essential active components in traditional
medicine for centuries. Their potential or confirmed effects include antiviral, antimutagenic, antiinflammatory, antibacterial, vasodilatory, and anticancer properties. The promotion of a plantbased diet, along with the benefits of consuming flavonoids, has recently become increasingly
attractive. 3-Hydroxyflavone (3HF) is the structural spine of flavonols, an important subgroup of
flavonoids. Although 3HF itself does not exist in plants per se, it exerts many of its effects because
of its characteristics that allow it to prevent free radical generation. This work is focused on the
characterization of 3HF complexes with zinc(II) and aluminium(III) ions (Zn-3HF and Al-3HF,
respectively). Besides this, a simple, fast, and low-priced spectrophotometric method for 3HF
determination, with very low LOD and LOQ, based on Zn-3HF and Al-3HF formation, was
established. A slight advantage is given to the modification with Al3+ ion on pH 4.91, due to very
low LOD and LOQ values of 1.83×10-7 molL-1
, and 5.50×10-7 molL-1
, respectively, and a high
correlation coefficient, R =0.99986. Furthermore, the antioxidant ability of Zn-3HF, Al-3HF, and
parent 3HF was examined by the ABTS and DPPH tests. They brought the Zn-3HF complex to
the fore as a potential antioxidative agent., Flavonoidi, jedinjenja biljnog porekla, vekovima su bili veoma važne aktivne komponente u tradicionalnoj medicini. Veliki broj njihovih potencijalnih ili već potvrđenih efekata uključuje antivirusna, antimutagena, antiinflamatorna, antibakterijska, vazodilatatorna i antikancerogena svojstva. Promovisanje biljne ishrane, uz isticanje koristi konzumiranja flavonoida, u današnje vreme postalo je sve privlačnije. 3-Hidroksiflavon (3HF) je strukturni stub svih flavonola, važne klase flavonoida. Iako sam 3HF ne postoji u biljkama per se, on ispoljava mnoge svoje efekte zahvaljujući osobini da sprečava stvaranja slobodnih radikala. Ovaj rad je fokusiran na karakterizaciju kompleksa 3HF sa jonima cinka(II) i aluminijuma(III) (Zn-3HF i Al-3HF, respektivno). Izvršena je karakterizacija ovih kompleksa i razvijena brza i pristupačna metoda za spektrofotometrijsko određivanje 3HF, na osnovu formiranja kompleksa Zn-3HF i Al-3HF, sa veoma niskim vrednostima LOD i LOQ. Mala prednost je data modifikaciji sa Al3+ na pH 4,91 zbog izuzetno niskih vrednosti LOD i LOQ, 1,83×10-7 mol L-1 , odnosno 5,50×10-7 mol L-1 , kao i visokog koeficijenta korelacije, R=0,99986. Pored toga, antioksidativni kapaciteti sintetizovanih kompleksa Zn-3HF i Al-3HF, kao i samog 3HF, ispitani su DPPH i ABTS testovima i doveli su Zn-3HF kompleks u prvi plan za dalja ispitivanja kao potencijalnog antioksidativnog agensa.",
publisher = "Beograd : Savez farmaceutskih udruženja Srbije",
journal = "Arhiv za farmaciju",
title = "Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles, Uporedno spektrofotometrijsko određivanje 3-hidroksiflavona bazirano na kompleksima cinka i aluminijuma i njihovi antioksidatni profili",
volume = "74",
number = "1",
pages = "92-104",
doi = "10.5937/arhfarm74-48637"
}

Pavun, L., Janošević-Ležaić, A.,& Uskoković-Marković, S.. (2024). Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles. in Arhiv za farmaciju
Beograd : Savez farmaceutskih udruženja Srbije., 74(1), 92-104.
https://doi.org/10.5937/arhfarm74-48637

Pavun L, Janošević-Ležaić A, Uskoković-Marković S. Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles. in Arhiv za farmaciju. 2024;74(1):92-104.
doi:10.5937/arhfarm74-48637 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, "Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles" in Arhiv za farmaciju, 74, no. 1 (2024):92-104,
https://doi.org/10.5937/arhfarm74-48637 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Spasojević, Danijela
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Milenković, Marina
AU  - Uskoković-Marković, Snežana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5420
AB  - Green, black, rooibos, and hibiscus tea (GT, BT, RT, and HT) aqueous extracts were prepared and
characterized in terms of total flavonoids (TFC) and total phenolic (TPC) contents and antioxidant and
antimicrobial activities. BT has the highest, while HT has the lowest TFC (1213 vs. 415 mg l–1
), while the
extracts’ TPCs (2283 – 7251 mg l–1
) decreased in the following order: BT > GT > RT > HT. Their antioxidant activities of 78.1 – 93.1% and 97.8 – 100% were determined according to DPPH and ABTS methods, respectively. BT and especially GT aqueous extracts possessed mild effects against several microorganisms. All examined extracts have an affinity for dyeing wool, cellulose acetate, polyamide, and cotton,
which is proven by the color strength values of 1.65–19.12. Wool, polyacrylonitrile, polyester, polyamide, cotton, and cellulose acetate functionalized with GT aqueous extract inhibited the growth of S. aureus
and E. coli, while polyacrylonitrile and cotton also inhibited the growth of E. faecalis, and C. albicans,
respectively. Wide inhibition zones for S. aureus were observed for fabrics functionalized with BT aqueous extract. Generally, the investigated fabrics showed very high (81.60 – 100%) ABTS radical scavenging ability independent of the extract used. TPCs have good linear correlations with the antioxidant activities of wool and polyacrylonitrile determined by the DPPH method. Fabrics with different chemical compositions dyed and/or functionalized with GT or BT aqueous extracts can be used to produce high-valueadded medical textiles with therapeutic, prophylactic, and protective functions. They can find potential applications in wound treatment, especially in skin wounds that are susceptible to infection with S. aureus.
Moreover, wool and cotton functionalized with GT or BT aqueous extract can also be considered for use in
disposable medical textiles like bandages and gauze used in the wound-healing process.
Keywords: tea aqueous extract; fabric; functionalization; dyeing; antioxidant and antimicrobial
AB  - Водните екстракти подготвени од црн, зелен, ројбуш и хибискус чај (GT, BT, RT и HT) се
карактеризирани од аспект на количество вкупни флавоноиди (TFC) и вкупни феноли (TPC), и
антиоксидациска и антимикробна активност. BT покажува најголема, а HT најмала TFC (1213 vs.
415 mg l–1), додека TPC во воденте екстракти (2283 – 7251 mg l–1) се намалува според следниов
редослед: BT > GT > RT > HT. Нивната антиоксидациска активност, одредена користејќи ги
методите DPPH и ABTS, се движи соодветно во опсег 78,1 – 93.1 % и 97,8 – 100 %. Водните
екстракти на BT и GT покажаа благ ефект врз одредени микроорганизми. Сите испитувани
екстракти имаат афинитет за боење волна, целулозен ацетат, полиамид и памук, што е потврдено
со одредување на јачина на бојата на ткаенините која изнесува 1,65 – 19.12. Волната,
полиакрилонитрилот, полиестерот, полиамидот, памукот и целулозниот ацетат функционализирани со воден екстракт од GT го инхибираат растот на S. aureus и E. coli, додека
полиакрилонитрилот и памукот соодветно го инхибираат растот на E. faecalis и C. albicans.
Широки инхибициони зони за S. aureus се воочени за ткаенините функционализирани со BT.
Општо, испитуваните ткаенини покажуваат многу висока (81,60 – 100 %) способност за
отстранување на ABTS-радикали. Утврдена е добра линеарна зависност помеѓу TPC во водните
екстракти и антиоксидациската активност на волната и полиакрилонитрилот одредени преку
методот DPPH. Ткаенините со различен хемиски состав обоени и/или функционализирани со
водни екстракти од GT или BT можат да се користат за производство на медицински текстил со
висока додадена вредност, кој има терапевтски, профилактички и заштитни функции.
Медицинските текстилни материјали имаат потенцијална примена за третман на рани, особено за
рани на кожа кои се подложни на инфекција со S. aureus. Покрај тоа, волната и памукот
функционализирани со водни екстракти од GT или BT можат да се користат за производство на
медицински завои и гази за еднократна употреба.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions
T1  - Карактеризација на водни екстракти од чаеви и нивна употреба за боење и функционализација на ткаенини со различен хемиски состав
VL  - 42
IS  - 2
SP  - 263
EP  - 273
DO  - 10.20450/mjcce2023.2698
ER  - 

@article{
author = "Pavun, Leposava and Spasojević, Danijela and Ivanovska, Aleksandra and Lađarević, Jelena and Milenković, Marina and Uskoković-Marković, Snežana",
year = "2023",
abstract = "Green, black, rooibos, and hibiscus tea (GT, BT, RT, and HT) aqueous extracts were prepared and
characterized in terms of total flavonoids (TFC) and total phenolic (TPC) contents and antioxidant and
antimicrobial activities. BT has the highest, while HT has the lowest TFC (1213 vs. 415 mg l–1
), while the
extracts’ TPCs (2283 – 7251 mg l–1
) decreased in the following order: BT > GT > RT > HT. Their antioxidant activities of 78.1 – 93.1% and 97.8 – 100% were determined according to DPPH and ABTS methods, respectively. BT and especially GT aqueous extracts possessed mild effects against several microorganisms. All examined extracts have an affinity for dyeing wool, cellulose acetate, polyamide, and cotton,
which is proven by the color strength values of 1.65–19.12. Wool, polyacrylonitrile, polyester, polyamide, cotton, and cellulose acetate functionalized with GT aqueous extract inhibited the growth of S. aureus
and E. coli, while polyacrylonitrile and cotton also inhibited the growth of E. faecalis, and C. albicans,
respectively. Wide inhibition zones for S. aureus were observed for fabrics functionalized with BT aqueous extract. Generally, the investigated fabrics showed very high (81.60 – 100%) ABTS radical scavenging ability independent of the extract used. TPCs have good linear correlations with the antioxidant activities of wool and polyacrylonitrile determined by the DPPH method. Fabrics with different chemical compositions dyed and/or functionalized with GT or BT aqueous extracts can be used to produce high-valueadded medical textiles with therapeutic, prophylactic, and protective functions. They can find potential applications in wound treatment, especially in skin wounds that are susceptible to infection with S. aureus.
Moreover, wool and cotton functionalized with GT or BT aqueous extract can also be considered for use in
disposable medical textiles like bandages and gauze used in the wound-healing process.
Keywords: tea aqueous extract; fabric; functionalization; dyeing; antioxidant and antimicrobial, Водните екстракти подготвени од црн, зелен, ројбуш и хибискус чај (GT, BT, RT и HT) се
карактеризирани од аспект на количество вкупни флавоноиди (TFC) и вкупни феноли (TPC), и
антиоксидациска и антимикробна активност. BT покажува најголема, а HT најмала TFC (1213 vs.
415 mg l–1), додека TPC во воденте екстракти (2283 – 7251 mg l–1) се намалува според следниов
редослед: BT > GT > RT > HT. Нивната антиоксидациска активност, одредена користејќи ги
методите DPPH и ABTS, се движи соодветно во опсег 78,1 – 93.1 % и 97,8 – 100 %. Водните
екстракти на BT и GT покажаа благ ефект врз одредени микроорганизми. Сите испитувани
екстракти имаат афинитет за боење волна, целулозен ацетат, полиамид и памук, што е потврдено
со одредување на јачина на бојата на ткаенините која изнесува 1,65 – 19.12. Волната,
полиакрилонитрилот, полиестерот, полиамидот, памукот и целулозниот ацетат функционализирани со воден екстракт од GT го инхибираат растот на S. aureus и E. coli, додека
полиакрилонитрилот и памукот соодветно го инхибираат растот на E. faecalis и C. albicans.
Широки инхибициони зони за S. aureus се воочени за ткаенините функционализирани со BT.
Општо, испитуваните ткаенини покажуваат многу висока (81,60 – 100 %) способност за
отстранување на ABTS-радикали. Утврдена е добра линеарна зависност помеѓу TPC во водните
екстракти и антиоксидациската активност на волната и полиакрилонитрилот одредени преку
методот DPPH. Ткаенините со различен хемиски состав обоени и/или функционализирани со
водни екстракти од GT или BT можат да се користат за производство на медицински текстил со
висока додадена вредност, кој има терапевтски, профилактички и заштитни функции.
Медицинските текстилни материјали имаат потенцијална примена за третман на рани, особено за
рани на кожа кои се подложни на инфекција со S. aureus. Покрај тоа, волната и памукот
функционализирани со водни екстракти од GT или BT можат да се користат за производство на
медицински завои и гази за еднократна употреба.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions, Карактеризација на водни екстракти од чаеви и нивна употреба за боење и функционализација на ткаенини со различен хемиски состав",
volume = "42",
number = "2",
pages = "263-273",
doi = "10.20450/mjcce2023.2698"
}

Pavun, L., Spasojević, D., Ivanovska, A., Lađarević, J., Milenković, M.,& Uskoković-Marković, S.. (2023). Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 42(2), 263-273.
https://doi.org/10.20450/mjcce2023.2698

Pavun L, Spasojević D, Ivanovska A, Lađarević J, Milenković M, Uskoković-Marković S. Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions. in Macedonian Journal of Chemistry and Chemical Engineering. 2023;42(2):263-273.
doi:10.20450/mjcce2023.2698 .

Pavun, Leposava, Spasojević, Danijela, Ivanovska, Aleksandra, Lađarević, Jelena, Milenković, Marina, Uskoković-Marković, Snežana, "Characterization of tea aqueous extracts and their utilization for dyeing and functionalizing fabrics of different chemical compositions" in Macedonian Journal of Chemistry and Chemical Engineering, 42, no. 2 (2023):263-273,
https://doi.org/10.20450/mjcce2023.2698 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Asanović, Koviljka
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
AU  - Mangovska, Biljana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4475
AB  - The present paper demonstrates a simple way for revalorization of differently softened cotton and cotton/elastane knitted fabric waste collected from the textile industry. Such waste was used as an adsorbent for Congo Red (CR) dye, whereby up to 96% removal efficiency was reached. The CR adsorption process onto cationic and silicone softened fabrics is in conformity with Langmuir (with maximum adsorption capacity of 12.533 mg/g) and Freundlich isotherms, respectively. Different adsorption of CR onto cationic and silicone softened fabrics is ascribed to the different softeners’ fixation to them, while the adsorption of CR operates in the same manner, via hydrophobic interactions. The adsorption kinetic data follow the pseudo-second-order model, while the equilibrium was reached after 90 min. Additionally, this study proposed a new circular economy solution for the disposal of fabric waste with adsorbed CR generating additional revenues. The volume electrical resistivity measurements confirmed that the knitted fabric wastes with adsorbed CR have 169–737 times lower resistivities (0.008–0.037 GΩ·cm) than before the adsorption. The inversely proportional correlation between fabrics’ adsorption efficiencies and their volume electrical resistivities after CR adsorption was found. Such knitted fabric waste with adsorbed CR could be defined as dissipative materials and could be used for providing antistatic protection.
PB  - Springer
T2  - Fibers and Polymers
T1  - Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste
VL  - 24
IS  - 2
SP  - 749
EP  - 758
DO  - 10.1007/s12221-023-00045-7
ER  - 

@article{
author = "Ivanovska, Aleksandra and Lađarević, Jelena and Asanović, Koviljka and Pavun, Leposava and Kostić, Mirjana and Mangovska, Biljana",
year = "2023",
abstract = "The present paper demonstrates a simple way for revalorization of differently softened cotton and cotton/elastane knitted fabric waste collected from the textile industry. Such waste was used as an adsorbent for Congo Red (CR) dye, whereby up to 96% removal efficiency was reached. The CR adsorption process onto cationic and silicone softened fabrics is in conformity with Langmuir (with maximum adsorption capacity of 12.533 mg/g) and Freundlich isotherms, respectively. Different adsorption of CR onto cationic and silicone softened fabrics is ascribed to the different softeners’ fixation to them, while the adsorption of CR operates in the same manner, via hydrophobic interactions. The adsorption kinetic data follow the pseudo-second-order model, while the equilibrium was reached after 90 min. Additionally, this study proposed a new circular economy solution for the disposal of fabric waste with adsorbed CR generating additional revenues. The volume electrical resistivity measurements confirmed that the knitted fabric wastes with adsorbed CR have 169–737 times lower resistivities (0.008–0.037 GΩ·cm) than before the adsorption. The inversely proportional correlation between fabrics’ adsorption efficiencies and their volume electrical resistivities after CR adsorption was found. Such knitted fabric waste with adsorbed CR could be defined as dissipative materials and could be used for providing antistatic protection.",
publisher = "Springer",
journal = "Fibers and Polymers",
title = "Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste",
volume = "24",
number = "2",
pages = "749-758",
doi = "10.1007/s12221-023-00045-7"
}

Ivanovska, A., Lađarević, J., Asanović, K., Pavun, L., Kostić, M.,& Mangovska, B.. (2023). Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste. in Fibers and Polymers
Springer., 24(2), 749-758.
https://doi.org/10.1007/s12221-023-00045-7

Ivanovska A, Lađarević J, Asanović K, Pavun L, Kostić M, Mangovska B. Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste. in Fibers and Polymers. 2023;24(2):749-758.
doi:10.1007/s12221-023-00045-7 .

Ivanovska, Aleksandra, Lađarević, Jelena, Asanović, Koviljka, Pavun, Leposava, Kostić, Mirjana, Mangovska, Biljana, "Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste" in Fibers and Polymers, 24, no. 2 (2023):749-758,
https://doi.org/10.1007/s12221-023-00045-7 . .

TY  - CONF
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5216
AB  - Flavonoids, widely distributed second metabolites of plants, have a large 
number of functions. Nowadays, with more nature-oriented lifestyle, the role in plants 
and potential benefits for humans and animals became more and more important.1 
3-Hydroxyflavone (3HF) represents the backbone of all flavonols, a 
widespread class of flavonoids. Interestingly, this compound is not found naturally in 
plants. Regardless, 3HF is commonly applied as a model molecule because it 
possesses an excited-state intramolecular proton transfer effect and may serve as a 
fluorescent probe in studies of either membranes or intermembrane proteins. It has 
also been shown that 3HF inhibits metastasis of human osteosarcoma cells and 
reduces tumor growth in vivo. 
With aim to find wider application of 3HF, its complexes with metal ions 
attract the attention of the researchers. Beside the characterization of zinc complex 
with 3HF, we reported the validation of the developed simple and low-cost 
spectrophotometric determination of 3-hydroxyflavone based on its zinc complex. 
Furthermore, the antioxidant capacities of the synthesized complex and 3HF itself 
were tested by the DPPH method, followed by the evaluation of more positive issues 
of zinc 3HF complex. The results of the performed study highlighted the suitability 
of zinc complex 3HF both for spectrophotometric determination, as well as to explore 
future applications of its potent bioactivity.
PB  - Society of Chemists and Technologists of Macedonia
C3  - 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia
T1  - Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5216
ER  - 

@conference{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana",
year = "2023",
abstract = "Flavonoids, widely distributed second metabolites of plants, have a large 
number of functions. Nowadays, with more nature-oriented lifestyle, the role in plants 
and potential benefits for humans and animals became more and more important.1 
3-Hydroxyflavone (3HF) represents the backbone of all flavonols, a 
widespread class of flavonoids. Interestingly, this compound is not found naturally in 
plants. Regardless, 3HF is commonly applied as a model molecule because it 
possesses an excited-state intramolecular proton transfer effect and may serve as a 
fluorescent probe in studies of either membranes or intermembrane proteins. It has 
also been shown that 3HF inhibits metastasis of human osteosarcoma cells and 
reduces tumor growth in vivo. 
With aim to find wider application of 3HF, its complexes with metal ions 
attract the attention of the researchers. Beside the characterization of zinc complex 
with 3HF, we reported the validation of the developed simple and low-cost 
spectrophotometric determination of 3-hydroxyflavone based on its zinc complex. 
Furthermore, the antioxidant capacities of the synthesized complex and 3HF itself 
were tested by the DPPH method, followed by the evaluation of more positive issues 
of zinc 3HF complex. The results of the performed study highlighted the suitability 
of zinc complex 3HF both for spectrophotometric determination, as well as to explore 
future applications of its potent bioactivity.",
publisher = "Society of Chemists and Technologists of Macedonia",
journal = "26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia",
title = "Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5216"
}

Pavun, L., Janošević-Ležaić, A.,& Uskoković-Marković, S.. (2023). Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles. in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia
Society of Chemists and Technologists of Macedonia..
https://hdl.handle.net/21.15107/rcub_farfar_5216

Pavun L, Janošević-Ležaić A, Uskoković-Marković S. Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles. in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_5216 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, "Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles" in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia (2023),
https://hdl.handle.net/21.15107/rcub_farfar_5216 .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Dojčinović, Biljana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Mijin, Dušan
AU  - Kostić, Mirjana
AU  - Svetozarević, Milica
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4519
AB  - This study is aimed at extending the soybean hulls' lifetime by their utilization as an adsorbent for metal ions (Cd2+ and Cu2+) and dyes (Reactive Yellow 39 (RY 39) and Acid Blue 225 (AB 225)). ATR-FTIR spectroscopy, FE-SEM microscopy, and zeta potential measurements were used for adsorbent characterization. The effect of the solution's pH, peroxidase extraction, adsorbent particle size, contact time, the pollutant's initial concentration, and temperature on the soybean hulls' adsorption potential was studied. Before peroxidase extraction, soybean hulls were capable of removing 72% Cd2+, 71% Cu2+ (at a pH of 5.00) or 81% RY 39, and 73% AB 225 (at a pH of 3.00). For further experiments, soybean hulls without peroxidase were used for several reasons: (1) due to their observed higher metal ion removal, (2) in order to reduce the waste disposal cost after the peroxidase (usually used for wastewater decolorization) extraction, and (3) since the soybean hulls without peroxidase possessed significantly lower secondary pollution than those with peroxidase. Cd2+ and Cu2+ removal was slightly increased when the smaller adsorbent fraction (710-1000 μm) was used, while the adsorbent particle size did not have an impact on dye removal. After 30 min of contact time, 92% and 88% of RY 39 and AB 225 were removed, respectively, while after the same contact time, 80% and 69% of Cd2+ and Cu2+ were removed, respectively. Adsorption of all tested pollutants follows a pseudo-second-order reaction through the fast adsorption, intraparticle diffusion, and final equilibrium stage. The maximal adsorption capacities determined by the Langmuir model were 21.10, 20.54, 16.54, and 17.23 mg/g for Cd2+, Cu2+, RY 39, and AB 225, respectively. Calculated thermodynamic parameters suggested that the adsorption of all pollutants is spontaneous and of endothermic character. Moreover, different binary mixtures were prepared, and the competitive adsorptions revealed that the soybean hulls are the most efficient adsorbent for the mixture of AB 225 and Cu2+. The findings of this study contribute to the soybean hulls' recovery after the peroxidase extraction and bring them into the circular economy concept.
PB  - Hindawi
T2  - Adsorption Science and Technology
T1  - Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes
VL  - 2023
DO  - 10.1155/2023/8532316
ER  - 

@article{
author = "Ivanovska, Aleksandra and Dojčinović, Biljana and Lađarević, Jelena and Pavun, Leposava and Mijin, Dušan and Kostić, Mirjana and Svetozarević, Milica",
year = "2023",
abstract = "This study is aimed at extending the soybean hulls' lifetime by their utilization as an adsorbent for metal ions (Cd2+ and Cu2+) and dyes (Reactive Yellow 39 (RY 39) and Acid Blue 225 (AB 225)). ATR-FTIR spectroscopy, FE-SEM microscopy, and zeta potential measurements were used for adsorbent characterization. The effect of the solution's pH, peroxidase extraction, adsorbent particle size, contact time, the pollutant's initial concentration, and temperature on the soybean hulls' adsorption potential was studied. Before peroxidase extraction, soybean hulls were capable of removing 72% Cd2+, 71% Cu2+ (at a pH of 5.00) or 81% RY 39, and 73% AB 225 (at a pH of 3.00). For further experiments, soybean hulls without peroxidase were used for several reasons: (1) due to their observed higher metal ion removal, (2) in order to reduce the waste disposal cost after the peroxidase (usually used for wastewater decolorization) extraction, and (3) since the soybean hulls without peroxidase possessed significantly lower secondary pollution than those with peroxidase. Cd2+ and Cu2+ removal was slightly increased when the smaller adsorbent fraction (710-1000 μm) was used, while the adsorbent particle size did not have an impact on dye removal. After 30 min of contact time, 92% and 88% of RY 39 and AB 225 were removed, respectively, while after the same contact time, 80% and 69% of Cd2+ and Cu2+ were removed, respectively. Adsorption of all tested pollutants follows a pseudo-second-order reaction through the fast adsorption, intraparticle diffusion, and final equilibrium stage. The maximal adsorption capacities determined by the Langmuir model were 21.10, 20.54, 16.54, and 17.23 mg/g for Cd2+, Cu2+, RY 39, and AB 225, respectively. Calculated thermodynamic parameters suggested that the adsorption of all pollutants is spontaneous and of endothermic character. Moreover, different binary mixtures were prepared, and the competitive adsorptions revealed that the soybean hulls are the most efficient adsorbent for the mixture of AB 225 and Cu2+. The findings of this study contribute to the soybean hulls' recovery after the peroxidase extraction and bring them into the circular economy concept.",
publisher = "Hindawi",
journal = "Adsorption Science and Technology",
title = "Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes",
volume = "2023",
doi = "10.1155/2023/8532316"
}

Ivanovska, A., Dojčinović, B., Lađarević, J., Pavun, L., Mijin, D., Kostić, M.,& Svetozarević, M.. (2023). Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes. in Adsorption Science and Technology
Hindawi., 2023.
https://doi.org/10.1155/2023/8532316

Ivanovska A, Dojčinović B, Lađarević J, Pavun L, Mijin D, Kostić M, Svetozarević M. Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes. in Adsorption Science and Technology. 2023;2023.
doi:10.1155/2023/8532316 .

Ivanovska, Aleksandra, Dojčinović, Biljana, Lađarević, Jelena, Pavun, Leposava, Mijin, Dušan, Kostić, Mirjana, Svetozarević, Milica, "Recovering the Soybean Hulls after Peroxidase Extraction and Their Application as Adsorbent for Metal Ions and Dyes" in Adsorption Science and Technology, 2023 (2023),
https://doi.org/10.1155/2023/8532316 . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Milošević, Marija
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Svirčev, Zorica
AU  - Kostić, Mirjana
AU  - Meriluoto, Juss
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4514
AB  - Featured Application: This work has a potential application in biocarpet engineering, which involves the use of cyanobacterial crusts either in the rehabilitation of damaged land surfaces or to combat desertification. Attempts to apply cyanobacterial crusts have not been completely successful so far because the growth of the initial inoculum requires more moisture than arid and semiarid environments can provide. To accelerate the development of the inoculum, it is necessary to provide additional moisture for the growth of cyanobacterial cells. Controlled water delivery could be achieved by using moisture-retentive material that is applied together with the inoculum in the treatment of damaged surfaces. Biocarpet engineering has the potential to solve not only some problems of damaged surfaces and desertification but also reduce and prevent air and water pollution caused by erosion. Raw jute fabric was treated with 0.5, 1.0, or 2.0% chitosan solution to improve its sorption properties (evaluated through the moisture sorption and adsorption of textile dye Reactive Orange 16 (RO 16)), which are essential for fabric utilization as geo-prebiotic polysaccharide support that should provide the necessary water for the growth of cyanobacterial communities in biocarpet engineering. Chitosan-treated fabrics possessed 39–78% higher moisture sorption values than the untreated ones. Concerning the dye adsorption, with the increase in its initial concentration, the adsorption potential of raw and fabrics treated with 0.5 or 1.0% chitosan solution was increased up to 1.9 times. The dye adsorption onto these fabrics was exothermic and enthalpy driven. By increasing the chitosan solution percentage up to 1.0%, fabric adsorption potential increased up to 2.2 times. An inverse relationship was observed in the case of the fabric treated with 2.0% chitosan solution, its adsorption potential decreased with increasing the initial dye concentration and temperature due to the different dominant binding interactions. Concerning the contact time, dye adsorption onto fabric treated with 1.0% chitosan solution was rapid in the first 2 h, while the equilibrium was attained after 4.5 h. The isotherm and kinetic data were represented by the Langmuir model and the pseudo-second-order kinetic model, respectively.
PB  - MDPI
T2  - Applied Sciences
T1  - Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties
VL  - 13
IS  - 4
DO  - 10.3390/app13042512
ER  - 

@article{
author = "Ivanovska, Aleksandra and Milošević, Marija and Lađarević, Jelena and Pavun, Leposava and Svirčev, Zorica and Kostić, Mirjana and Meriluoto, Juss",
year = "2023",
abstract = "Featured Application: This work has a potential application in biocarpet engineering, which involves the use of cyanobacterial crusts either in the rehabilitation of damaged land surfaces or to combat desertification. Attempts to apply cyanobacterial crusts have not been completely successful so far because the growth of the initial inoculum requires more moisture than arid and semiarid environments can provide. To accelerate the development of the inoculum, it is necessary to provide additional moisture for the growth of cyanobacterial cells. Controlled water delivery could be achieved by using moisture-retentive material that is applied together with the inoculum in the treatment of damaged surfaces. Biocarpet engineering has the potential to solve not only some problems of damaged surfaces and desertification but also reduce and prevent air and water pollution caused by erosion. Raw jute fabric was treated with 0.5, 1.0, or 2.0% chitosan solution to improve its sorption properties (evaluated through the moisture sorption and adsorption of textile dye Reactive Orange 16 (RO 16)), which are essential for fabric utilization as geo-prebiotic polysaccharide support that should provide the necessary water for the growth of cyanobacterial communities in biocarpet engineering. Chitosan-treated fabrics possessed 39–78% higher moisture sorption values than the untreated ones. Concerning the dye adsorption, with the increase in its initial concentration, the adsorption potential of raw and fabrics treated with 0.5 or 1.0% chitosan solution was increased up to 1.9 times. The dye adsorption onto these fabrics was exothermic and enthalpy driven. By increasing the chitosan solution percentage up to 1.0%, fabric adsorption potential increased up to 2.2 times. An inverse relationship was observed in the case of the fabric treated with 2.0% chitosan solution, its adsorption potential decreased with increasing the initial dye concentration and temperature due to the different dominant binding interactions. Concerning the contact time, dye adsorption onto fabric treated with 1.0% chitosan solution was rapid in the first 2 h, while the equilibrium was attained after 4.5 h. The isotherm and kinetic data were represented by the Langmuir model and the pseudo-second-order kinetic model, respectively.",
publisher = "MDPI",
journal = "Applied Sciences",
title = "Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties",
volume = "13",
number = "4",
doi = "10.3390/app13042512"
}

Ivanovska, A., Milošević, M., Lađarević, J., Pavun, L., Svirčev, Z., Kostić, M.,& Meriluoto, J.. (2023). Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties. in Applied Sciences
MDPI., 13(4).
https://doi.org/10.3390/app13042512

Ivanovska A, Milošević M, Lađarević J, Pavun L, Svirčev Z, Kostić M, Meriluoto J. Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties. in Applied Sciences. 2023;13(4).
doi:10.3390/app13042512 .

Ivanovska, Aleksandra, Milošević, Marija, Lađarević, Jelena, Pavun, Leposava, Svirčev, Zorica, Kostić, Mirjana, Meriluoto, Juss, "Obtaining Polysaccharide-Based Fabrics with Improved Moisture Sorption and Dye Adsorption Properties" in Applied Sciences, 13, no. 4 (2023),
https://doi.org/10.3390/app13042512 . .

TY  - CONF
AU  - Ivanovska, Aleksandra
AU  - Milenković, Jovana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5234
AB  - Abstract
Green tea aqueous extract was prepared and characterized regarding total flavonoids and total
phenolic contents as well as antioxidant activity (assessed by ABTS method). The characterized
aqueous extract was used for dyeing and functionalization of 100% cotton and cotton/linen
(47%/53% and 70%/30%) fabrics. Fabric color strength (K/S) values and their antioxidant
activities before and after washing were compared. The obtained results revealed that 100%
cotton (GTI), 47%/53% cotton/linen (GTII), and 70%/30% cotton/linen (GTIII) fabrics have
K/S values ranging between 8.33 and 10.85. After one washing cycle, these values decreased
significantly. On the other hand, dyed fabrics showed excellent (100 %) ABTS radical
scavenging ability which remained excellent (GTII) or decreased to medium (GTI and GTIII)
levels after one washing cycle. Based on the obtained results, it can be concluded that 47%/53%
cotton/linen fabric is the most suitable for functional clothing capable of trapping the free radial
of oxygen species. The current paper represents a step towards a more sustainable textile
industry that could undoubtedly contribute to overcoming the environmental problems caused
by the textile industry
PB  - University of Szeged, Hungary
C3  - 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings
T1  - Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract
SP  - 163
EP  - 166
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5234
ER  - 

@conference{
author = "Ivanovska, Aleksandra and Milenković, Jovana and Lađarević, Jelena and Pavun, Leposava and Kostić, Mirjana",
year = "2023",
abstract = "Abstract
Green tea aqueous extract was prepared and characterized regarding total flavonoids and total
phenolic contents as well as antioxidant activity (assessed by ABTS method). The characterized
aqueous extract was used for dyeing and functionalization of 100% cotton and cotton/linen
(47%/53% and 70%/30%) fabrics. Fabric color strength (K/S) values and their antioxidant
activities before and after washing were compared. The obtained results revealed that 100%
cotton (GTI), 47%/53% cotton/linen (GTII), and 70%/30% cotton/linen (GTIII) fabrics have
K/S values ranging between 8.33 and 10.85. After one washing cycle, these values decreased
significantly. On the other hand, dyed fabrics showed excellent (100 %) ABTS radical
scavenging ability which remained excellent (GTII) or decreased to medium (GTI and GTIII)
levels after one washing cycle. Based on the obtained results, it can be concluded that 47%/53%
cotton/linen fabric is the most suitable for functional clothing capable of trapping the free radial
of oxygen species. The current paper represents a step towards a more sustainable textile
industry that could undoubtedly contribute to overcoming the environmental problems caused
by the textile industry",
publisher = "University of Szeged, Hungary",
journal = "29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings",
title = "Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract",
pages = "163-166",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5234"
}

Ivanovska, A., Milenković, J., Lađarević, J., Pavun, L.,& Kostić, M.. (2023). Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract. in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings
University of Szeged, Hungary., 163-166.
https://hdl.handle.net/21.15107/rcub_farfar_5234

Ivanovska A, Milenković J, Lađarević J, Pavun L, Kostić M. Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract. in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings. 2023;:163-166.
https://hdl.handle.net/21.15107/rcub_farfar_5234 .

Ivanovska, Aleksandra, Milenković, Jovana, Lađarević, Jelena, Pavun, Leposava, Kostić, Mirjana, "Obtaining colored antioxidant cotton and cotton/linen fabrics using green tea aqueous extract" in 29th International Symposium on Analytical and Environmental Problems, November 13-14, 2023, Szeged, Hungary, Proceedings (2023):163-166,
https://hdl.handle.net/21.15107/rcub_farfar_5234 .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Veljović, Sonja
AU  - Reljić, Mirjana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Natić, Maja
AU  - Kostić, Mirjana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5059
AB  - ABSTRACT
This study reports the successful transformation of mulberry wood waste
into natural textile dye and adsorbent for Pb2+ ions from an aqueous solution. Fabrics of different chemical compositions were dyed using mulberry
wood extract, whereas wool possessed the best appearance and color fastness to washing. Among differently dyed wool fabrics, those dyed with 15%
extract for 5 h has the highest color strength (K/S = 11.24) and antioxidant
activity (83.5%), and the best color and antioxidant activity fastness to
washing, making it appropriate for protecting the skin from diverse damages
by decelerating the effect of free radical. Moreover, it could be suggested
that the binding mechanism proceeds via strong hydrogen bonds between
wool surface carboxylate groups and characteristic phenolics found in the
extract (dominantly taxifolin, oxyresveratrol, ellagic acid, and tannins). The
mulberry wood solid parts separated after the extraction were further evaluated as adsorbents for Pb2+ ions. The highest lead removal was achieved at
a solution pH of 5.5, while the equilibrium removal was reached after 4 h of
contact time. At 20 mg/l initial lead concentration, the mulberry wood waste
removal efficiency was 98.8%. The results of this study represent a step
forward to a healthier, cleaner, and more sustainable society
AB  - 摘要
本研究报告了将桑木废料成功转化为天然纺织染料和水溶液中Pb2+ 离子
的吸附剂. 不同化学成分的织物用桑木提取物染色, 而羊毛的外观和耐洗色
牢度最好. 在不同染色的羊毛织物中, 用15%提取物染色5小时的羊毛织物
具有最高的颜色强度 (K/S = 11.24) 和抗氧化活性 (83.5%), 并且具有最佳的
颜色和抗氧化活性耐洗牢度, 因此适合通过减缓自由基的作用来保护皮肤
免受各种损伤. 此外, 可以认为, 结合机制是通过羊毛表面羧基和提取物中
的特征酚类 (主要是紫杉醇, 白藜芦醇, 鞣花酸和单宁) 之间的强氢键进行
的. 提取后分离的桑木固体部分被进一步评估为Pb2+ 离子的吸附剂. 在溶
液pH值为5.5时, 铅的去除率最高, 而接触时间为4小时后, 铅的去除率达到
平衡. 在20mg/l的初始铅浓度下, 桑木废弃物的去除率为98.8%. 这项研究的
结果代表着朝着一个更健康, 更清洁, 更可持续的社会迈进了一步.
PB  - Taylor & Francis
T2  - Journal of Natural Fibers
T1  - Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste
VL  - 19
IS  - 15
SP  - 11050
EP  - 11063
DO  - 10.1080/15440478.2021.2009398
ER  - 

@article{
author = "Ivanovska, Aleksandra and Veljović, Sonja and Reljić, Mirjana and Lađarević, Jelena and Pavun, Leposava and Natić, Maja and Kostić, Mirjana",
year = "2022",
abstract = "ABSTRACT
This study reports the successful transformation of mulberry wood waste
into natural textile dye and adsorbent for Pb2+ ions from an aqueous solution. Fabrics of different chemical compositions were dyed using mulberry
wood extract, whereas wool possessed the best appearance and color fastness to washing. Among differently dyed wool fabrics, those dyed with 15%
extract for 5 h has the highest color strength (K/S = 11.24) and antioxidant
activity (83.5%), and the best color and antioxidant activity fastness to
washing, making it appropriate for protecting the skin from diverse damages
by decelerating the effect of free radical. Moreover, it could be suggested
that the binding mechanism proceeds via strong hydrogen bonds between
wool surface carboxylate groups and characteristic phenolics found in the
extract (dominantly taxifolin, oxyresveratrol, ellagic acid, and tannins). The
mulberry wood solid parts separated after the extraction were further evaluated as adsorbents for Pb2+ ions. The highest lead removal was achieved at
a solution pH of 5.5, while the equilibrium removal was reached after 4 h of
contact time. At 20 mg/l initial lead concentration, the mulberry wood waste
removal efficiency was 98.8%. The results of this study represent a step
forward to a healthier, cleaner, and more sustainable society, 摘要
本研究报告了将桑木废料成功转化为天然纺织染料和水溶液中Pb2+ 离子
的吸附剂. 不同化学成分的织物用桑木提取物染色, 而羊毛的外观和耐洗色
牢度最好. 在不同染色的羊毛织物中, 用15%提取物染色5小时的羊毛织物
具有最高的颜色强度 (K/S = 11.24) 和抗氧化活性 (83.5%), 并且具有最佳的
颜色和抗氧化活性耐洗牢度, 因此适合通过减缓自由基的作用来保护皮肤
免受各种损伤. 此外, 可以认为, 结合机制是通过羊毛表面羧基和提取物中
的特征酚类 (主要是紫杉醇, 白藜芦醇, 鞣花酸和单宁) 之间的强氢键进行
的. 提取后分离的桑木固体部分被进一步评估为Pb2+ 离子的吸附剂. 在溶
液pH值为5.5时, 铅的去除率最高, 而接触时间为4小时后, 铅的去除率达到
平衡. 在20mg/l的初始铅浓度下, 桑木废弃物的去除率为98.8%. 这项研究的
结果代表着朝着一个更健康, 更清洁, 更可持续的社会迈进了一步.",
publisher = "Taylor & Francis",
journal = "Journal of Natural Fibers",
title = "Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste",
volume = "19",
number = "15",
pages = "11050-11063",
doi = "10.1080/15440478.2021.2009398"
}

Ivanovska, A., Veljović, S., Reljić, M., Lađarević, J., Pavun, L., Natić, M.,& Kostić, M.. (2022). Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste. in Journal of Natural Fibers
Taylor & Francis., 19(15), 11050-11063.
https://doi.org/10.1080/15440478.2021.2009398

Ivanovska A, Veljović S, Reljić M, Lađarević J, Pavun L, Natić M, Kostić M. Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste. in Journal of Natural Fibers. 2022;19(15):11050-11063.
doi:10.1080/15440478.2021.2009398 .

Ivanovska, Aleksandra, Veljović, Sonja, Reljić, Mirjana, Lađarević, Jelena, Pavun, Leposava, Natić, Maja, Kostić, Mirjana, "Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste" in Journal of Natural Fibers, 19, no. 15 (2022):11050-11063,
https://doi.org/10.1080/15440478.2021.2009398 . .

TY  - JOUR
AU  - Gledović, Ana
AU  - Bajuk-Bogdanović, Danica
AU  - Uskoković-Marković, Snežana
AU  - Pavun, Leposava
AU  - Savić, Snežana
AU  - Janošević-Ležaić, Aleksandra
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4170
AB  - In this study several essential oils (EOs): basil - BA, lemon balm - LB and oregano - OR were incorporated into nanoemulsions (NEs) as prospective carriers for natural and sensitive bioactives. NEs were prepared via the phase inversion composition (PIC) method, which is an energy-efficient cold process. Physicochemical stability of NEs was confirmed by particle size distribution analysis, electrical conductivity and pH value measurements, as well as by optical microscopy observations. The type of EO and the surfactant and oil mix concentration were found to be crucial factors governing the NE properties and stability. Raman spectra of the EOs confirmed main active ingredients and provided detection of interactions with the nanocarrier, which is a novel application of this technique. The antioxidant activity towards DPPH radical in methanol was concentration-dependent with a similar trend for individual oils and oil-loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable change in the order of activity after EO nanonisation at higher EO concentrations. Overall, it was found that OR-NE was the most effective and stable system, since OR acted as a co-stabiliser in the NE formulation, and its remarkably high antioxidant activity was successfully preserved during 6 months of storage.
AB  - U ovoj studiji nekoliko različitih etarskih ulja (EU): bosiljak – BO, matičnjak – MA i origano – OR inkor-
porirano je u nanoemulzije (NE) kao potencijalne nosače za prirodne i osetljive bioaktivne sastojke. NE
su pripremljene pomoću metode inverzije faza (engl. phase inversion composition – PIC method) koja
predstavlja niskoenergetski i ekonomičan postupak izrade. Fizičkohemijska stabilnost nanoemulzija
potvrđena je analizom raspodele veličina kapi, merenjem električne provodljivosti i pH vrednosti, kao i
optičkom mikroskopijom. Nađeno je da su vrsta EU i koncentracija smeše surfaktanata i uljane faze dva
ključna faktora koja su uticala na karakteristike i stabilnost dobijenih emulzija. Tehnikom Ramanske
spektroskopije potvrđeni su glavni aktivni sastojci etarskih ulja i detektovane su moguće interakcije sa
nanonosačem, što predstavlja noviju primenu pomenute tehnike. Pokazano je da antioksidantna
aktivnost prema DPPH radikalu u metanolu zavisi od koncentracije, sa sličnim trendom za čista etarska
ulja i za nanoemulzije sa uljima (OR> MA> BO). Međutim, ABTS test u vodenoj sredini pokazao je izrazite
promene u redosledu aktivnosti sa povećanjem koncentracije EU i nakon nanonizacije EU. Generalno,
dokazano je da je OR-NE najefikasniji i najstabiliniji sistem, s obzirom da je ulje origana ispoljilo ulogu
kostabilizatora u formulaciji, uz istovremeno očuvanje njegove veoma visoke antioksidantne aktivnosti
u obliku nanoemulzije, tokom 6 meseci čuvanja.
PB  - Association of the Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection
T1  - Niskoenergetske nanoemulzije kao nosači za etarska ulja u topikalnim formulacijama za antioksidantnu zaštitu kože
VL  - 76
IS  - 1
SP  - 29
EP  - 42
DO  - 10.2298/HEMIND210509004G
ER  - 

@article{
author = "Gledović, Ana and Bajuk-Bogdanović, Danica and Uskoković-Marković, Snežana and Pavun, Leposava and Savić, Snežana and Janošević-Ležaić, Aleksandra",
year = "2022",
abstract = "In this study several essential oils (EOs): basil - BA, lemon balm - LB and oregano - OR were incorporated into nanoemulsions (NEs) as prospective carriers for natural and sensitive bioactives. NEs were prepared via the phase inversion composition (PIC) method, which is an energy-efficient cold process. Physicochemical stability of NEs was confirmed by particle size distribution analysis, electrical conductivity and pH value measurements, as well as by optical microscopy observations. The type of EO and the surfactant and oil mix concentration were found to be crucial factors governing the NE properties and stability. Raman spectra of the EOs confirmed main active ingredients and provided detection of interactions with the nanocarrier, which is a novel application of this technique. The antioxidant activity towards DPPH radical in methanol was concentration-dependent with a similar trend for individual oils and oil-loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable change in the order of activity after EO nanonisation at higher EO concentrations. Overall, it was found that OR-NE was the most effective and stable system, since OR acted as a co-stabiliser in the NE formulation, and its remarkably high antioxidant activity was successfully preserved during 6 months of storage., U ovoj studiji nekoliko različitih etarskih ulja (EU): bosiljak – BO, matičnjak – MA i origano – OR inkor-
porirano je u nanoemulzije (NE) kao potencijalne nosače za prirodne i osetljive bioaktivne sastojke. NE
su pripremljene pomoću metode inverzije faza (engl. phase inversion composition – PIC method) koja
predstavlja niskoenergetski i ekonomičan postupak izrade. Fizičkohemijska stabilnost nanoemulzija
potvrđena je analizom raspodele veličina kapi, merenjem električne provodljivosti i pH vrednosti, kao i
optičkom mikroskopijom. Nađeno je da su vrsta EU i koncentracija smeše surfaktanata i uljane faze dva
ključna faktora koja su uticala na karakteristike i stabilnost dobijenih emulzija. Tehnikom Ramanske
spektroskopije potvrđeni su glavni aktivni sastojci etarskih ulja i detektovane su moguće interakcije sa
nanonosačem, što predstavlja noviju primenu pomenute tehnike. Pokazano je da antioksidantna
aktivnost prema DPPH radikalu u metanolu zavisi od koncentracije, sa sličnim trendom za čista etarska
ulja i za nanoemulzije sa uljima (OR> MA> BO). Međutim, ABTS test u vodenoj sredini pokazao je izrazite
promene u redosledu aktivnosti sa povećanjem koncentracije EU i nakon nanonizacije EU. Generalno,
dokazano je da je OR-NE najefikasniji i najstabiliniji sistem, s obzirom da je ulje origana ispoljilo ulogu
kostabilizatora u formulaciji, uz istovremeno očuvanje njegove veoma visoke antioksidantne aktivnosti
u obliku nanoemulzije, tokom 6 meseci čuvanja.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection, Niskoenergetske nanoemulzije kao nosači za etarska ulja u topikalnim formulacijama za antioksidantnu zaštitu kože",
volume = "76",
number = "1",
pages = "29-42",
doi = "10.2298/HEMIND210509004G"
}

Gledović, A., Bajuk-Bogdanović, D., Uskoković-Marković, S., Pavun, L., Savić, S.,& Janošević-Ležaić, A.. (2022). Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection. in Hemijska industrija
Association of the Chemical Engineers of Serbia., 76(1), 29-42.
https://doi.org/10.2298/HEMIND210509004G

Gledović A, Bajuk-Bogdanović D, Uskoković-Marković S, Pavun L, Savić S, Janošević-Ležaić A. Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection. in Hemijska industrija. 2022;76(1):29-42.
doi:10.2298/HEMIND210509004G .

Gledović, Ana, Bajuk-Bogdanović, Danica, Uskoković-Marković, Snežana, Pavun, Leposava, Savić, Snežana, Janošević-Ležaić, Aleksandra, "Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection" in Hemijska industrija, 76, no. 1 (2022):29-42,
https://doi.org/10.2298/HEMIND210509004G . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Branković, Ivana
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5060
AB  - The raw jute fabric was oxidized with 0.2% or 0.4% NaIO4 for 60 or 120 min to obtain valuable adsorbents for the
textile dye Congo Red (CR). Batch adsorption experiments were carried out as a function of solution pH, contact
time, initial CR concentration, and temperature. At an initial CR concentration of 25 mg/L, the raw jute possessed the
lowest adsorption due to the lowest availability and content of carboxyl and aldehyde groups capable of binding dye. The
fabrics oxidized for 60 min with 0.2% NaIO4 and 120 min with 0.4% NaIO4 reached equilibrium adsorption after 240 and
330 min, respectively. The adsorption of CR onto studied fabrics followed the pseudo-second-order model indicating
that the chemisorption process is primarily represented. Within the studied range of CR concentrations (25–100 mg/L),
its adsorption onto fabric oxidized for 120 min with 0.4% NaIO4 obeys the Langmuir isotherm model (i.e. adsorption
occurs at specific, energetically equivalent adsorbent sites with monolayer coverage of CR over a homogeneous surface),
wherein the calculated maximal adsorption capacity is 12.863 mg/g. A thermodynamic study revealed the spontaneous
and endothermic character of CR adsorption onto jute fabric. Based on the recorded ATR-FTIR spectra before and after
CR adsorption, it is suggested that repulsion, hydrogen bonds, and π-π stacking interactions are involved in the binding
of CR onto jute fabrics.
PB  - Sage Journals
T2  - Journal of Engineered Fibers and Fabrics
T1  - Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution
VL  - 17
DO  - 10.1177/15589250221101380
ER  - 

@article{
author = "Ivanovska, Aleksandra and Branković, Ivana and Lađarević, Jelena and Pavun, Leposava and Kostić, Mirjana",
year = "2022",
abstract = "The raw jute fabric was oxidized with 0.2% or 0.4% NaIO4 for 60 or 120 min to obtain valuable adsorbents for the
textile dye Congo Red (CR). Batch adsorption experiments were carried out as a function of solution pH, contact
time, initial CR concentration, and temperature. At an initial CR concentration of 25 mg/L, the raw jute possessed the
lowest adsorption due to the lowest availability and content of carboxyl and aldehyde groups capable of binding dye. The
fabrics oxidized for 60 min with 0.2% NaIO4 and 120 min with 0.4% NaIO4 reached equilibrium adsorption after 240 and
330 min, respectively. The adsorption of CR onto studied fabrics followed the pseudo-second-order model indicating
that the chemisorption process is primarily represented. Within the studied range of CR concentrations (25–100 mg/L),
its adsorption onto fabric oxidized for 120 min with 0.4% NaIO4 obeys the Langmuir isotherm model (i.e. adsorption
occurs at specific, energetically equivalent adsorbent sites with monolayer coverage of CR over a homogeneous surface),
wherein the calculated maximal adsorption capacity is 12.863 mg/g. A thermodynamic study revealed the spontaneous
and endothermic character of CR adsorption onto jute fabric. Based on the recorded ATR-FTIR spectra before and after
CR adsorption, it is suggested that repulsion, hydrogen bonds, and π-π stacking interactions are involved in the binding
of CR onto jute fabrics.",
publisher = "Sage Journals",
journal = "Journal of Engineered Fibers and Fabrics",
title = "Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution",
volume = "17",
doi = "10.1177/15589250221101380"
}

Ivanovska, A., Branković, I., Lađarević, J., Pavun, L.,& Kostić, M.. (2022). Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution. in Journal of Engineered Fibers and Fabrics
Sage Journals., 17.
https://doi.org/10.1177/15589250221101380

Ivanovska A, Branković I, Lađarević J, Pavun L, Kostić M. Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution. in Journal of Engineered Fibers and Fabrics. 2022;17.
doi:10.1177/15589250221101380 .

Ivanovska, Aleksandra, Branković, Ivana, Lađarević, Jelena, Pavun, Leposava, Kostić, Mirjana, "Oxidized jute as a valuable adsorbent for Congo Red from an aqueous solution" in Journal of Engineered Fibers and Fabrics, 17 (2022),
https://doi.org/10.1177/15589250221101380 . .

TY  - CONF
AU  - Gledović, Ana
AU  - Bajuk-Bogdanović, Danica
AU  - Uskoković-Marković, Snežana
AU  - Pavun, Leposava
AU  - Savić, Snežana
AU  - Janošević-Ležaić, Aleksandra
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4673
AB  - Aromatic plants have been used since ancient times as a source of essential oils (EOs)
which are known as natural remedies in traditional medicine systems – phytotherapy and
aromatherapy, but they are also widely used for everyday purposes (for example, as fragrant
components in skincare preparations and perfumery; as flavours and natural preservatives
in food industry). It is known that many EOs contain molecules with considerable
antioxidant activity, such as phenolic compounds, flavonoids and terpenoids, acting alone or
synergistically. Besides antimicrobial action, EOs prepared from plants form the Lamiaceae
family, such as basil −BA (Ocimum basilicum), oregano – OR (Origanum vulgare) and lemon
balm − LB (Melissa officinalis) leaves are reported to scavenge free radicals (1). Therefore,
these particular EOs and their bioactives could be good candidates for skin-protective
formulations. Nanoemulsions (NEs), especially those produced by low energy methods, are
recently proposed as prospective carriers for sensitive and natural ingredients such as EOs,
in order to ensure their stabilization. Additionally, some EOs can act as cosurfactants and
promote low energy nanoemulsification. Having in mind that EOs cannot be used undiluted,
oil-in-water NEs could be an appropriate delivery system, representing fluid formulations
with ultra-fine droplets, pleasant visual appearance, and improved stability compared to
classic macroemulsions (2). Firstly, NEs were prepared different EOs (BA, OR or LB) with
polyethylene glycol free (PEG-free) natural surfactants/emollients mixture (containing
polyglycerol-4 laurate as the main surfactant) suitable for cold processing via the Phase
inversion composition (PIC) method. NEs physicochemical stability was confirmed by
particle size distribution analysis, electrical conductivity and pH value measurements, as
well as by optical microscopy observations. The type of EO and the concentration of
surfactants/emollient mixture were proven to be crucial factors governing NE properties
and stability. Raman spectra of EOs verified their main active ingredients and detected
possible interactions with the nanocarrier (3). The antioxidant activity towards the DPPH
radical in methanol was concentration-dependent with a similar trend for neat oils and oil-
loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable
change in the order of activity with increased EO concentration and after EO nanonisation.
Overall, the highest antioxidant activity was observed for OR and OR-loaded NE (> 95%
INH ABTS and > 85% INH DPPH), implying at some optimal package of OR within the nanocarrier
which preserved its high antioxidant performance and ensured its stability during 6 months
of storage.
AB  - Aromatične biljke koriste se od davnina za dobijanje etarskih ulja (EOs) koja su
poznata kao prirodni lekovi u tradicionalnim sistemima lečenja – fitoterapiji i aromaterapiji,
a takođe je široko rasprostranjena njihova upotreba u svakodnevnom životu (na primer, kao
mirisne komponente u kozmetičkim proizvodima i parfemima; kao korigensi ukusa i
prirodni konzervansi u prehrambenoj industriji). Brojna EOs sadrže molekule kao što su
fenolna jedinjenja, flavonoidi i terpenoidi koji ispoljavaju značajnu antioksidativnu aktivnost,
delujući samostalno ili sinergistički. Pored antimikrobnog dejstva, EOs dobijena iz listova
biljaka familije Lamiaceae, kao što je bosiljak - BA (Ocimum basilicum), origano – OR
(Origanum vulgare) i matičnjak − LB (Melissa officinalis) deluju kao hvatači slobodnih
radikala (1). Prema tome, pomenuta EOs i njihovi bioaktivni sastojci mogu biti dobri
kandidati za razvoj formulacija za zaštitu kože. Nanoemulzije (NEs), posebno one
proizvedene niskoenergetskim metodama, odnedavno se predlažu kao prospektivni nosači
za prirodne i osetljive sastojke poput EOs, sa ciljem da se obezbedi njihova stabilizacija.
Dodatno, neka EOs imaju ulogu kosurfaktanta i pospešuju niskoenergetsku
nanoemulzifikaciju. Imajući u vidu da se EOs ne mogu koristiti nerazblažena, NEs ulje u vodi
tipa mogu biti adekvatni nosači, s obzirom da su u pitanju fluidne formulacije sa ultra-finim
veličinama kapi, prijatnim vizuelnim izgledom, kao i poboljšanom stabilnošću u poređenju sa
klasičnim makroemulzijama (2). Prvo su pripremljene NEs sa različitim EOs (BA, OR ili LB),
sa smešom prirodnim surfaktanata i emolijensa (bez polietilenglikola - PEG, gde je
poligliceril-4 laurat glavni surfaktant) koja je pogodna za izradu na hladno primenom
metode inverzije faza (engl. Phase inversion composition ‐ PIC method). Fizičkohemijska
stabilnost NEs potvrđena je analizom distribucije veličina kapi, merenjem električne
provodljivosti i pH vrednosti, kao i optičkom mikroskopijom. Nađeno je da su vrsta EO i
koncentracija smeše surfaktanata i emolijensa ključni faktori koji utiču na karakteristike i
stabilnost dobijenih NE. Tehnikom Ramanske spektroskopije potvrđeni su glavni aktivni
sastojci etarskih ulja i detektovane su moguće interakcije sa nanonosačem. Pokazano je da je
antioksidativna aktivnost prema DPPH radikalu u metanolu koncentraciono zavisna, sa
sličnim trendom za čista etarska ulja i za NEs sa uljima (OR> LB> BA). Međutim, ABTS test u
vodenoj sredini pokazao je izrazite promene u redosledu aktivnosti sa povećanjem
koncentracije EO i nakon nanonizacije EO. Generalno, najjača aktioksidativna aktivnost
primećena je u slučaju OR i OR-NE (> 95% INH ABTS i > 85% INH DPPH), što ukazuje na
optimalno pakovanje OR unutar nanonosača čime su očuvane njegove antioksidativne
performanse i obezbeđena stabilnost tokom 6 meseci čuvanja.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection
T1  - Niskoenergetske nanoemulzije kao potencijalni nosači za etarska ulja u formulacijama za antioksidativnu zaštitu kože
VL  - 71
IS  - 5 suplement
SP  - S96
EP  - S99
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4673
ER  - 

@conference{
author = "Gledović, Ana and Bajuk-Bogdanović, Danica and Uskoković-Marković, Snežana and Pavun, Leposava and Savić, Snežana and Janošević-Ležaić, Aleksandra",
year = "2021",
abstract = "Aromatic plants have been used since ancient times as a source of essential oils (EOs)
which are known as natural remedies in traditional medicine systems – phytotherapy and
aromatherapy, but they are also widely used for everyday purposes (for example, as fragrant
components in skincare preparations and perfumery; as flavours and natural preservatives
in food industry). It is known that many EOs contain molecules with considerable
antioxidant activity, such as phenolic compounds, flavonoids and terpenoids, acting alone or
synergistically. Besides antimicrobial action, EOs prepared from plants form the Lamiaceae
family, such as basil −BA (Ocimum basilicum), oregano – OR (Origanum vulgare) and lemon
balm − LB (Melissa officinalis) leaves are reported to scavenge free radicals (1). Therefore,
these particular EOs and their bioactives could be good candidates for skin-protective
formulations. Nanoemulsions (NEs), especially those produced by low energy methods, are
recently proposed as prospective carriers for sensitive and natural ingredients such as EOs,
in order to ensure their stabilization. Additionally, some EOs can act as cosurfactants and
promote low energy nanoemulsification. Having in mind that EOs cannot be used undiluted,
oil-in-water NEs could be an appropriate delivery system, representing fluid formulations
with ultra-fine droplets, pleasant visual appearance, and improved stability compared to
classic macroemulsions (2). Firstly, NEs were prepared different EOs (BA, OR or LB) with
polyethylene glycol free (PEG-free) natural surfactants/emollients mixture (containing
polyglycerol-4 laurate as the main surfactant) suitable for cold processing via the Phase
inversion composition (PIC) method. NEs physicochemical stability was confirmed by
particle size distribution analysis, electrical conductivity and pH value measurements, as
well as by optical microscopy observations. The type of EO and the concentration of
surfactants/emollient mixture were proven to be crucial factors governing NE properties
and stability. Raman spectra of EOs verified their main active ingredients and detected
possible interactions with the nanocarrier (3). The antioxidant activity towards the DPPH
radical in methanol was concentration-dependent with a similar trend for neat oils and oil-
loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable
change in the order of activity with increased EO concentration and after EO nanonisation.
Overall, the highest antioxidant activity was observed for OR and OR-loaded NE (> 95%
INH ABTS and > 85% INH DPPH), implying at some optimal package of OR within the nanocarrier
which preserved its high antioxidant performance and ensured its stability during 6 months
of storage., Aromatične biljke koriste se od davnina za dobijanje etarskih ulja (EOs) koja su
poznata kao prirodni lekovi u tradicionalnim sistemima lečenja – fitoterapiji i aromaterapiji,
a takođe je široko rasprostranjena njihova upotreba u svakodnevnom životu (na primer, kao
mirisne komponente u kozmetičkim proizvodima i parfemima; kao korigensi ukusa i
prirodni konzervansi u prehrambenoj industriji). Brojna EOs sadrže molekule kao što su
fenolna jedinjenja, flavonoidi i terpenoidi koji ispoljavaju značajnu antioksidativnu aktivnost,
delujući samostalno ili sinergistički. Pored antimikrobnog dejstva, EOs dobijena iz listova
biljaka familije Lamiaceae, kao što je bosiljak - BA (Ocimum basilicum), origano – OR
(Origanum vulgare) i matičnjak − LB (Melissa officinalis) deluju kao hvatači slobodnih
radikala (1). Prema tome, pomenuta EOs i njihovi bioaktivni sastojci mogu biti dobri
kandidati za razvoj formulacija za zaštitu kože. Nanoemulzije (NEs), posebno one
proizvedene niskoenergetskim metodama, odnedavno se predlažu kao prospektivni nosači
za prirodne i osetljive sastojke poput EOs, sa ciljem da se obezbedi njihova stabilizacija.
Dodatno, neka EOs imaju ulogu kosurfaktanta i pospešuju niskoenergetsku
nanoemulzifikaciju. Imajući u vidu da se EOs ne mogu koristiti nerazblažena, NEs ulje u vodi
tipa mogu biti adekvatni nosači, s obzirom da su u pitanju fluidne formulacije sa ultra-finim
veličinama kapi, prijatnim vizuelnim izgledom, kao i poboljšanom stabilnošću u poređenju sa
klasičnim makroemulzijama (2). Prvo su pripremljene NEs sa različitim EOs (BA, OR ili LB),
sa smešom prirodnim surfaktanata i emolijensa (bez polietilenglikola - PEG, gde je
poligliceril-4 laurat glavni surfaktant) koja je pogodna za izradu na hladno primenom
metode inverzije faza (engl. Phase inversion composition ‐ PIC method). Fizičkohemijska
stabilnost NEs potvrđena je analizom distribucije veličina kapi, merenjem električne
provodljivosti i pH vrednosti, kao i optičkom mikroskopijom. Nađeno je da su vrsta EO i
koncentracija smeše surfaktanata i emolijensa ključni faktori koji utiču na karakteristike i
stabilnost dobijenih NE. Tehnikom Ramanske spektroskopije potvrđeni su glavni aktivni
sastojci etarskih ulja i detektovane su moguće interakcije sa nanonosačem. Pokazano je da je
antioksidativna aktivnost prema DPPH radikalu u metanolu koncentraciono zavisna, sa
sličnim trendom za čista etarska ulja i za NEs sa uljima (OR> LB> BA). Međutim, ABTS test u
vodenoj sredini pokazao je izrazite promene u redosledu aktivnosti sa povećanjem
koncentracije EO i nakon nanonizacije EO. Generalno, najjača aktioksidativna aktivnost
primećena je u slučaju OR i OR-NE (> 95% INH ABTS i > 85% INH DPPH), što ukazuje na
optimalno pakovanje OR unutar nanonosača čime su očuvane njegove antioksidativne
performanse i obezbeđena stabilnost tokom 6 meseci čuvanja.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection, Niskoenergetske nanoemulzije kao potencijalni nosači za etarska ulja u formulacijama za antioksidativnu zaštitu kože",
volume = "71",
number = "5 suplement",
pages = "S96-S99",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4673"
}

Gledović, A., Bajuk-Bogdanović, D., Uskoković-Marković, S., Pavun, L., Savić, S.,& Janošević-Ležaić, A.. (2021). Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 71(5 suplement), S96-S99.
https://hdl.handle.net/21.15107/rcub_farfar_4673

Gledović A, Bajuk-Bogdanović D, Uskoković-Marković S, Pavun L, Savić S, Janošević-Ležaić A. Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection. in Arhiv za farmaciju. 2021;71(5 suplement):S96-S99.
https://hdl.handle.net/21.15107/rcub_farfar_4673 .

Gledović, Ana, Bajuk-Bogdanović, Danica, Uskoković-Marković, Snežana, Pavun, Leposava, Savić, Snežana, Janošević-Ležaić, Aleksandra, "Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection" in Arhiv za farmaciju, 71, no. 5 suplement (2021):S96-S99,
https://hdl.handle.net/21.15107/rcub_farfar_4673 .

TY  - JOUR
AU  - Janošević-Ležaić, Aleksandra
AU  - Pejić, Nataša
AU  - Goronja, Jelena
AU  - Pavun, Leposava
AU  - Ðikanović, Danijela
AU  - Malenović, Anđelija
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4056
AB  - The effect of acetonitrile (ACN) on the micellization of a cationic surfactant, cetyltrimethylammo-nium bromide (CTAB), in aqueous solutions at different temperatures was studied. The critical micellar concentration (CMC) as well as the degree of counter ion dissociation () of CTAB in aqueous ACN mixtures (1020 % v/v) at various temperatures (291.2298.2 K) were determined by electrical conduc-tivity measurements, while steady-state fluorescence measurements were used to determine several CMCs (for comparison) and a micellar aggregation number (Nagg) as well. At a fixed temperature, both an increase in CMC and a decrease in Nagg were observed for an increase in ACN in the solvent mixture. With a temperature increase, CMC values increased for 10 % (v/v) ACN, while for both 15 % and 20 % (v/v) ACN, CMC values were a minimum at T = 295.2 K with a temperature increase. In addition, some aspects related to the Krafft temperature behavior of CTAB in the examined micellar systems are dis-cussed.
AB  - Беше испитано влијанието на ацетонитрилот (ACN) врз мицелизацијата на катјонски сурфактант, цетилтриметиламониум бромид (CTAB), во водна средина на различни температури. Со помош на мерења на електричната спроводливост, беа определени критичната мицеларна концентрација (CMC), и степенот на дисоцијација на спротивните јони () на CTAB во водни смеси на ACN (1020 % v/v) на различни температури (291,2298,2 K), додека за определување на неколку CMC (за споредба), како и на мицеларен агрегационен број (Nagg) беа употребени рамнотежни флуоресцентни мерења. На фиксна температура беше забележано зголемување на CMC и намалување на Nagg со зголемување на ACN во смесата на растворот. Со зголемување на температурата вредностите на CMC се зголемија за 10 % (v/v) ACN, додека за 15 % и за 20 % (v/v) ACN, вредностите на CMC при зголемување на температурата на T = 295,2 K беа минимални. Покрај тоа, дискутирани се некои аспекти што се поврзани со однесувањето на температурата на Krafft на CTAB во испитуваните мицеларни системи.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies
T1  - Мицеларни својства на цетилтриметиламониум бромид во смесата од ацетонитрил вода: кондуктометриски и флуоресцентни студии
VL  - 40
IS  - 2
SP  - 277
EP  - 287
DO  - 10.20450/MJCCE.2021.2394
ER  - 

@article{
author = "Janošević-Ležaić, Aleksandra and Pejić, Nataša and Goronja, Jelena and Pavun, Leposava and Ðikanović, Danijela and Malenović, Anđelija",
year = "2021",
abstract = "The effect of acetonitrile (ACN) on the micellization of a cationic surfactant, cetyltrimethylammo-nium bromide (CTAB), in aqueous solutions at different temperatures was studied. The critical micellar concentration (CMC) as well as the degree of counter ion dissociation () of CTAB in aqueous ACN mixtures (1020 % v/v) at various temperatures (291.2298.2 K) were determined by electrical conduc-tivity measurements, while steady-state fluorescence measurements were used to determine several CMCs (for comparison) and a micellar aggregation number (Nagg) as well. At a fixed temperature, both an increase in CMC and a decrease in Nagg were observed for an increase in ACN in the solvent mixture. With a temperature increase, CMC values increased for 10 % (v/v) ACN, while for both 15 % and 20 % (v/v) ACN, CMC values were a minimum at T = 295.2 K with a temperature increase. In addition, some aspects related to the Krafft temperature behavior of CTAB in the examined micellar systems are dis-cussed., Беше испитано влијанието на ацетонитрилот (ACN) врз мицелизацијата на катјонски сурфактант, цетилтриметиламониум бромид (CTAB), во водна средина на различни температури. Со помош на мерења на електричната спроводливост, беа определени критичната мицеларна концентрација (CMC), и степенот на дисоцијација на спротивните јони () на CTAB во водни смеси на ACN (1020 % v/v) на различни температури (291,2298,2 K), додека за определување на неколку CMC (за споредба), како и на мицеларен агрегационен број (Nagg) беа употребени рамнотежни флуоресцентни мерења. На фиксна температура беше забележано зголемување на CMC и намалување на Nagg со зголемување на ACN во смесата на растворот. Со зголемување на температурата вредностите на CMC се зголемија за 10 % (v/v) ACN, додека за 15 % и за 20 % (v/v) ACN, вредностите на CMC при зголемување на температурата на T = 295,2 K беа минимални. Покрај тоа, дискутирани се некои аспекти што се поврзани со однесувањето на температурата на Krafft на CTAB во испитуваните мицеларни системи.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies, Мицеларни својства на цетилтриметиламониум бромид во смесата од ацетонитрил вода: кондуктометриски и флуоресцентни студии",
volume = "40",
number = "2",
pages = "277-287",
doi = "10.20450/MJCCE.2021.2394"
}

Janošević-Ležaić, A., Pejić, N., Goronja, J., Pavun, L., Ðikanović, D.,& Malenović, A.. (2021). Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 40(2), 277-287.
https://doi.org/10.20450/MJCCE.2021.2394

Janošević-Ležaić A, Pejić N, Goronja J, Pavun L, Ðikanović D, Malenović A. Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(2):277-287.
doi:10.20450/MJCCE.2021.2394 .

Janošević-Ležaić, Aleksandra, Pejić, Nataša, Goronja, Jelena, Pavun, Leposava, Ðikanović, Danijela, Malenović, Anđelija, "Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 2 (2021):277-287,
https://doi.org/10.20450/MJCCE.2021.2394 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Tanasković, Slađana
AU  - Ušjak, Dušan
AU  - Milenković, Marina
AU  - Uskoković-Marković, Snežana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4055
AB  - The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. Novel lipoprotein biomarkers are suggested as possible targets for improving the outcomes of patients at higher risk for CVD, and their impact on major CV events and mortality have previously been investigated. Innovative antidiabetic therapies have recently shown a significant reduction in atherogenic lipoproteins, beyond their effects on glucose parameters; it has also been suggested that such anti-atherogenic effect may represent a valuable mechanistic explanation for the cardiovascular benefit of, at least, some of the novel antidiabetic agents, such as glucagon-like peptide-1 receptor agonists. This emphasizes the need for further research in the field in order to clearly assess the effects of innovative treatments on different novel biomarkers, including atherogenic lipoproteins, such as small dense low-density lipoprotein (LDL), lipoprotein(a) (Lp(a)) and dysfunctional high-density lipoprotein (HDL). The current article discusses the clinical importance of novel lipid biomarkers for better management of patients in order to overcome residual cardiovascular risk.
AB  - Постои постојана потреба од ефикасни лекови, комбинации на лекови и методи за спречување на бактериски и вирусни инфекции, вклучувајќи го и коронавирусот. Познато е дека улогата на елементи во траги во зајакнување на човековиот имун систем е значајна. Витамините, микроелементите, вклучувајќи цинк, железо, селен, магнезиум и бакар, масните киселини омега-3 играат значајна физиолошка улога во унапредување на имуниот систем. Цинкот е неопходен микроелемент за основните ензимски физиолошки процеси. Тој игра важна улога во делбата на клетките и е вклучен во развојот на клетки одговорни за неспецифичен имунитет. Познато е дека недостигот на цинк ги предиспонира пациентите на вирусни инфекции поради намалениот антивирусен имунитет. Од друга страна, флавоноидите како метаболити на растенијата играат важна улога во спречување на оксидативен стрес. Овој труд има за цел да ја дискутира in vitro улогата на цинкот, флавонидите и нивните комплекси, како и нивните антиоксидативни и антимикорбни активности. Разгледана е и оправданоста за истовремена употреба на цинк и флавоноиди.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?
T1  - Aнтиоксидативен капацитет и антимикробни ефекти на комплекси
на цинк со флавоноиди – дали постои синергизам?
VL  - 40
IS  - 2
SP  - 231
EP  - 239
DO  - 10.20450/mjcce.2021.2401
ER  - 

@article{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Tanasković, Slađana and Ušjak, Dušan and Milenković, Marina and Uskoković-Marković, Snežana",
year = "2021",
abstract = "The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. Novel lipoprotein biomarkers are suggested as possible targets for improving the outcomes of patients at higher risk for CVD, and their impact on major CV events and mortality have previously been investigated. Innovative antidiabetic therapies have recently shown a significant reduction in atherogenic lipoproteins, beyond their effects on glucose parameters; it has also been suggested that such anti-atherogenic effect may represent a valuable mechanistic explanation for the cardiovascular benefit of, at least, some of the novel antidiabetic agents, such as glucagon-like peptide-1 receptor agonists. This emphasizes the need for further research in the field in order to clearly assess the effects of innovative treatments on different novel biomarkers, including atherogenic lipoproteins, such as small dense low-density lipoprotein (LDL), lipoprotein(a) (Lp(a)) and dysfunctional high-density lipoprotein (HDL). The current article discusses the clinical importance of novel lipid biomarkers for better management of patients in order to overcome residual cardiovascular risk., Постои постојана потреба од ефикасни лекови, комбинации на лекови и методи за спречување на бактериски и вирусни инфекции, вклучувајќи го и коронавирусот. Познато е дека улогата на елементи во траги во зајакнување на човековиот имун систем е значајна. Витамините, микроелементите, вклучувајќи цинк, железо, селен, магнезиум и бакар, масните киселини омега-3 играат значајна физиолошка улога во унапредување на имуниот систем. Цинкот е неопходен микроелемент за основните ензимски физиолошки процеси. Тој игра важна улога во делбата на клетките и е вклучен во развојот на клетки одговорни за неспецифичен имунитет. Познато е дека недостигот на цинк ги предиспонира пациентите на вирусни инфекции поради намалениот антивирусен имунитет. Од друга страна, флавоноидите како метаболити на растенијата играат важна улога во спречување на оксидативен стрес. Овој труд има за цел да ја дискутира in vitro улогата на цинкот, флавонидите и нивните комплекси, како и нивните антиоксидативни и антимикорбни активности. Разгледана е и оправданоста за истовремена употреба на цинк и флавоноиди.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?, Aнтиоксидативен капацитет и антимикробни ефекти на комплекси
на цинк со флавоноиди – дали постои синергизам?",
volume = "40",
number = "2",
pages = "231-239",
doi = "10.20450/mjcce.2021.2401"
}

Pavun, L., Janošević-Ležaić, A., Tanasković, S., Ušjak, D., Milenković, M.,& Uskoković-Marković, S.. (2021). Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 40(2), 231-239.
https://doi.org/10.20450/mjcce.2021.2401

Pavun L, Janošević-Ležaić A, Tanasković S, Ušjak D, Milenković M, Uskoković-Marković S. Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(2):231-239.
doi:10.20450/mjcce.2021.2401 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Tanasković, Slađana, Ušjak, Dušan, Milenković, Marina, Uskoković-Marković, Snežana, "Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 2 (2021):231-239,
https://doi.org/10.20450/mjcce.2021.2401 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3809
AB  - Morin is one of the flavonoids with intensive antioxidant activity. With the aim to use its benefits on human health, there is an increasing trend to pay attention to its content in food or supplements.  The  simplicity  and low  cost  of  spectrophotometric determination  based  on  the formation of a morin complex with Zn2+ ion (stoichiometric ratio 1 : 1), at pH 7.98 and 392 nm, give  it  an  advantage  over  other  methods  that  can  be  used  for  morin  quantification.  The concentration range over which the response was linear was 0.151 – 4.533 mg L-1. The limit of detection (LOD) and the limit of quantification (LOQ) were 0.030 mg L-1 and 0.091 mg L-1, respectively. The developed method was successfully applied for the determination of the morin content in strawberries. Additionally, the antioxidative abilities of strawberry extracts and morin, determined by DPPH and FRAP tests, were compared and discussed.
AB  - Morin je jedan od flavonoida sa vrlo izraženom antioksidantnom aktivnošću. Sa ciljem korišćenja njegovih pozitivnih efekata na ljudsko zdravlje, u porastu je trend interesovanja za njegov sadržaj u hrani ili suplementima. U radu je predstavljena jednostavna i pristupačna spektrofotometrijska metoda određivanja morina, zasnovana na formiranju kompleksa morina sa Zn2+ jonom (u stehiometrijskom odnosu 1 : 1, na pH 7,98 i 392 nm), što joj daje prednost u odnosu na druge metode koje se mogu koristiti za kvantifikaciju morina. Metoda pokazuje linearnost odgovora u koncentracionom opsegu 0,151 - 4,533 mg L-1, pri čemu limit detekcije (LOD) iznosi 0,030 mg L-1 a limit kvantifikacije metode (LOQ) je 0,091 mg L-1. Razvijena metoda je uspešno primenjena za određivanje sadržaja morina u jagodama. Takođe, prikazani su i komentarisani rezultati određivanja antioksidativne aktivnosti jagoda i morina, DPPH i FRAP testovima.
PB  - Beograd : Savez farmaceutskih udruženja Srbije
T2  - Arhiv za farmaciju
T1  - Spectrophotometric determination of morin in strawberries and their antioxidant activity
T1  - Spektrofotometrijsko određivanje sadržaja morina u jagodama i njihove antioksidantne aktivnosti
VL  - 71
IS  - 1
SP  - 55
EP  - 71
DO  - 10.5937/arhfarm71-30503
ER  - 

@article{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana",
year = "2021",
abstract = "Morin is one of the flavonoids with intensive antioxidant activity. With the aim to use its benefits on human health, there is an increasing trend to pay attention to its content in food or supplements.  The  simplicity  and low  cost  of  spectrophotometric determination  based  on  the formation of a morin complex with Zn2+ ion (stoichiometric ratio 1 : 1), at pH 7.98 and 392 nm, give  it  an  advantage  over  other  methods  that  can  be  used  for  morin  quantification.  The concentration range over which the response was linear was 0.151 – 4.533 mg L-1. The limit of detection (LOD) and the limit of quantification (LOQ) were 0.030 mg L-1 and 0.091 mg L-1, respectively. The developed method was successfully applied for the determination of the morin content in strawberries. Additionally, the antioxidative abilities of strawberry extracts and morin, determined by DPPH and FRAP tests, were compared and discussed., Morin je jedan od flavonoida sa vrlo izraženom antioksidantnom aktivnošću. Sa ciljem korišćenja njegovih pozitivnih efekata na ljudsko zdravlje, u porastu je trend interesovanja za njegov sadržaj u hrani ili suplementima. U radu je predstavljena jednostavna i pristupačna spektrofotometrijska metoda određivanja morina, zasnovana na formiranju kompleksa morina sa Zn2+ jonom (u stehiometrijskom odnosu 1 : 1, na pH 7,98 i 392 nm), što joj daje prednost u odnosu na druge metode koje se mogu koristiti za kvantifikaciju morina. Metoda pokazuje linearnost odgovora u koncentracionom opsegu 0,151 - 4,533 mg L-1, pri čemu limit detekcije (LOD) iznosi 0,030 mg L-1 a limit kvantifikacije metode (LOQ) je 0,091 mg L-1. Razvijena metoda je uspešno primenjena za određivanje sadržaja morina u jagodama. Takođe, prikazani su i komentarisani rezultati određivanja antioksidativne aktivnosti jagoda i morina, DPPH i FRAP testovima.",
publisher = "Beograd : Savez farmaceutskih udruženja Srbije",
journal = "Arhiv za farmaciju",
title = "Spectrophotometric determination of morin in strawberries and their antioxidant activity, Spektrofotometrijsko određivanje sadržaja morina u jagodama i njihove antioksidantne aktivnosti",
volume = "71",
number = "1",
pages = "55-71",
doi = "10.5937/arhfarm71-30503"
}

Pavun, L., Janošević-Ležaić, A.,& Uskoković-Marković, S.. (2021). Spectrophotometric determination of morin in strawberries and their antioxidant activity. in Arhiv za farmaciju
Beograd : Savez farmaceutskih udruženja Srbije., 71(1), 55-71.
https://doi.org/10.5937/arhfarm71-30503

Pavun L, Janošević-Ležaić A, Uskoković-Marković S. Spectrophotometric determination of morin in strawberries and their antioxidant activity. in Arhiv za farmaciju. 2021;71(1):55-71.
doi:10.5937/arhfarm71-30503 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, "Spectrophotometric determination of morin in strawberries and their antioxidant activity" in Arhiv za farmaciju, 71, no. 1 (2021):55-71,
https://doi.org/10.5937/arhfarm71-30503 . .

TY  - CONF
AU  - Ivanovska, Aleksandra
AU  - Asanović, Koviljka
AU  - Cerović, Dragana
AU  - Pavun, Leposava
AU  - Dojčinović, Biljana
AU  - Mihajlovski, Katarina
AU  - Kostić, Mirjana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5214
AB  - This study aims to obtain multifunctional jute fabrics by using simple alkali
and oxidative protocols. Performed chemical treatments contributed to obtaining jute fabrics
with enhanced electro-physical and sorption properties. Moreover, the jute fabrics were
functionalized by incorporation of Ag+ (resulted in decreased volume electrical resistivity
and excellent antibacterial activity) and in-situ synthesis of Cu-based nanoparticles (resulted
in 38-88 times higher energy storage from an external electric field). Following the increased
focus on the concept of circular economy, the possibility of jute fabric waste revalorization
for wastewater purification (from Cu2+, Zn2+, Ni2+) was examined.
AB  - Cilj ovog istraživanja je dobijanje multifunkcionalnih tkanina od jute
upotrebom jednostavnih alkalnih i oksidativnih postupaka. Ovi hemijski tretmani omogućili
su dobijanje tkanina od jute sa poboljšanim elektro-fizičkim i sorpcionim svojstvima.
Tkanine od jute su, takođe, bile funkcionalizovane jonima srebra (što je rezultovalo
smanjenom specifičnom zapreminskom električnom otpornošću i odličnom antibakterijskom
aktivnošću) i in-situ sintezom nanočestica na bazi bakra (što je rezultovalo 38-88 puta većim
skladištenjem energije iz spoljašnjeg električnog polja). U skladu sa načelima cirkularne
ekonomije, ispitana je mogućnost revalorizacije otpada tkanina od jute za prečišćavanje
otpadnih voda (od Cu2+, Zn2+, Ni2+- jona).
PB  - Union of Engineers and Textile Technicians of Serbia
C3  - IV International Scientific Conference "Contemporary Trends and Innovations in the Textile Industry", CT&ITI 2021, Belgrade, 16-17 th September, 2021, Proceedings
T1  - Simple protocols for obtaining multifunctional jute fabrics
T1  - Jednostavni postupci za dobijanje multifunkcionalnih tkanina od jute
SP  - 3
EP  - 12
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5214
ER  - 

@conference{
author = "Ivanovska, Aleksandra and Asanović, Koviljka and Cerović, Dragana and Pavun, Leposava and Dojčinović, Biljana and Mihajlovski, Katarina and Kostić, Mirjana",
year = "2021",
abstract = "This study aims to obtain multifunctional jute fabrics by using simple alkali
and oxidative protocols. Performed chemical treatments contributed to obtaining jute fabrics
with enhanced electro-physical and sorption properties. Moreover, the jute fabrics were
functionalized by incorporation of Ag+ (resulted in decreased volume electrical resistivity
and excellent antibacterial activity) and in-situ synthesis of Cu-based nanoparticles (resulted
in 38-88 times higher energy storage from an external electric field). Following the increased
focus on the concept of circular economy, the possibility of jute fabric waste revalorization
for wastewater purification (from Cu2+, Zn2+, Ni2+) was examined., Cilj ovog istraživanja je dobijanje multifunkcionalnih tkanina od jute
upotrebom jednostavnih alkalnih i oksidativnih postupaka. Ovi hemijski tretmani omogućili
su dobijanje tkanina od jute sa poboljšanim elektro-fizičkim i sorpcionim svojstvima.
Tkanine od jute su, takođe, bile funkcionalizovane jonima srebra (što je rezultovalo
smanjenom specifičnom zapreminskom električnom otpornošću i odličnom antibakterijskom
aktivnošću) i in-situ sintezom nanočestica na bazi bakra (što je rezultovalo 38-88 puta većim
skladištenjem energije iz spoljašnjeg električnog polja). U skladu sa načelima cirkularne
ekonomije, ispitana je mogućnost revalorizacije otpada tkanina od jute za prečišćavanje
otpadnih voda (od Cu2+, Zn2+, Ni2+- jona).",
publisher = "Union of Engineers and Textile Technicians of Serbia",
journal = "IV International Scientific Conference "Contemporary Trends and Innovations in the Textile Industry", CT&ITI 2021, Belgrade, 16-17 th September, 2021, Proceedings",
title = "Simple protocols for obtaining multifunctional jute fabrics, Jednostavni postupci za dobijanje multifunkcionalnih tkanina od jute",
pages = "3-12",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5214"
}

Ivanovska, A., Asanović, K., Cerović, D., Pavun, L., Dojčinović, B., Mihajlovski, K.,& Kostić, M.. (2021). Simple protocols for obtaining multifunctional jute fabrics. in IV International Scientific Conference "Contemporary Trends and Innovations in the Textile Industry", CT&ITI 2021, Belgrade, 16-17 th September, 2021, Proceedings
Union of Engineers and Textile Technicians of Serbia., 3-12.
https://hdl.handle.net/21.15107/rcub_farfar_5214

Ivanovska A, Asanović K, Cerović D, Pavun L, Dojčinović B, Mihajlovski K, Kostić M. Simple protocols for obtaining multifunctional jute fabrics. in IV International Scientific Conference "Contemporary Trends and Innovations in the Textile Industry", CT&ITI 2021, Belgrade, 16-17 th September, 2021, Proceedings. 2021;:3-12.
https://hdl.handle.net/21.15107/rcub_farfar_5214 .

Ivanovska, Aleksandra, Asanović, Koviljka, Cerović, Dragana, Pavun, Leposava, Dojčinović, Biljana, Mihajlovski, Katarina, Kostić, Mirjana, "Simple protocols for obtaining multifunctional jute fabrics" in IV International Scientific Conference "Contemporary Trends and Innovations in the Textile Industry", CT&ITI 2021, Belgrade, 16-17 th September, 2021, Proceedings (2021):3-12,
https://hdl.handle.net/21.15107/rcub_farfar_5214 .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Pavun, Leposava
AU  - Dojčinović, Biljana
AU  - Kostić, Mirjana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3955
AB  - Raw jute fabric was chemically modified with 1 % NaOH for 30 min,  17.5 % NaOH for 5 min or with 0.7 % NaClO2 for 30 and 60 min to study the  influence of changes in the chemical composition of the fabrics and quantity of  carboxyl groups on the biosorption capacity of the fabrics for nickel ions. The  effects of contact time and initial concentration of nickel ions on the biosorp- tion capacity of the fabrics were also investigated. The obtained results rev- ealed that the biosorption of nickel ions can be explained by the pseudo-sec- ond-order kinetic model, while the experimental isotherm data fit better with  the Langmuir model. The calculated ratios between maximal biosorption cap- acity (6.30–12.06 mg g-1) of the jute fabrics and carboxyl group quantity indi- cated that approximately half of the carboxyl groups of the fabrics’ would be  involved in binding nickel ions during biosorption. Therefore, the quantity of  carboxyl groups can be used to predict the maximal biosorption capacity of jute  fabrics toward nickel ions. In the case of oxidized jute fabrics, the lignin rem- oval, and consequently increased content of cellulose and hemicelluloses, also  contributed to a higher biosorption capacity.
AB  - Сирова тканина од јуте је хемијски модификована 1 % NaOH у току 30 min, 17,5 %  NaOH у току 5 min или 0,7 % NaClO2 у току 30 и 60 min у циљу испитивања утицаја промена хемијског састава и садржаја карбоксилних група на биосорпциони капацитет тканина  према  јонима  никла.  Такође,  испитиван  је  и  утицај  времена  контакта  тканина  са  раствором  NiSO4  и  почетне  концентрације  раствора  никла  на  биосорпциони  капацитет  тканина од јуте. Добијени резултати указују на то да се процес биосорпције никла може  описати  кинетичким  моделом  псеудо-другог  реда,  а  равнотежне  вредности  добијене  за  сорпцију никла се боље слажу са Langmuir адсорпционом изотермом. Израчунати однос  између  максималних  биосорпционих  капацитета  тканина  од  јуте  (6,30–12,06  mg  g-1)  и  садржаја  карбоксилних  група  указују  на  то  да  ће  приближно  половина  карбоксилних  група  учествовати  у  везивању  јона  никла  током  биосорпције.  Према  томе,  садржај  карбоксилних  група  се  може  користити  као  индикатор  максималног  биосорпционог  капацитета тканина од јуте према јонима никла. Код оксидисане тканине, уклањање лигнина  које  је  праћено  са  повећањем  садржаја  целулозе  и  хемицелулоза  је  такође  допринело  већем биосорпционом капацитету.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics
T1  - Биосорпција јона никла на тканинама од јуте: кинетичка и  изотермска испитивања
VL  - 86
IS  - 9
SP  - 885
EP  - 897
DO  - 10.2298/JSC210209030I
ER  - 

@article{
author = "Ivanovska, Aleksandra and Pavun, Leposava and Dojčinović, Biljana and Kostić, Mirjana",
year = "2021",
abstract = "Raw jute fabric was chemically modified with 1 % NaOH for 30 min,  17.5 % NaOH for 5 min or with 0.7 % NaClO2 for 30 and 60 min to study the  influence of changes in the chemical composition of the fabrics and quantity of  carboxyl groups on the biosorption capacity of the fabrics for nickel ions. The  effects of contact time and initial concentration of nickel ions on the biosorp- tion capacity of the fabrics were also investigated. The obtained results rev- ealed that the biosorption of nickel ions can be explained by the pseudo-sec- ond-order kinetic model, while the experimental isotherm data fit better with  the Langmuir model. The calculated ratios between maximal biosorption cap- acity (6.30–12.06 mg g-1) of the jute fabrics and carboxyl group quantity indi- cated that approximately half of the carboxyl groups of the fabrics’ would be  involved in binding nickel ions during biosorption. Therefore, the quantity of  carboxyl groups can be used to predict the maximal biosorption capacity of jute  fabrics toward nickel ions. In the case of oxidized jute fabrics, the lignin rem- oval, and consequently increased content of cellulose and hemicelluloses, also  contributed to a higher biosorption capacity., Сирова тканина од јуте је хемијски модификована 1 % NaOH у току 30 min, 17,5 %  NaOH у току 5 min или 0,7 % NaClO2 у току 30 и 60 min у циљу испитивања утицаја промена хемијског састава и садржаја карбоксилних група на биосорпциони капацитет тканина  према  јонима  никла.  Такође,  испитиван  је  и  утицај  времена  контакта  тканина  са  раствором  NiSO4  и  почетне  концентрације  раствора  никла  на  биосорпциони  капацитет  тканина од јуте. Добијени резултати указују на то да се процес биосорпције никла може  описати  кинетичким  моделом  псеудо-другог  реда,  а  равнотежне  вредности  добијене  за  сорпцију никла се боље слажу са Langmuir адсорпционом изотермом. Израчунати однос  између  максималних  биосорпционих  капацитета  тканина  од  јуте  (6,30–12,06  mg  g-1)  и  садржаја  карбоксилних  група  указују  на  то  да  ће  приближно  половина  карбоксилних  група  учествовати  у  везивању  јона  никла  током  биосорпције.  Према  томе,  садржај  карбоксилних  група  се  може  користити  као  индикатор  максималног  биосорпционог  капацитета тканина од јуте према јонима никла. Код оксидисане тканине, уклањање лигнина  које  је  праћено  са  повећањем  садржаја  целулозе  и  хемицелулоза  је  такође  допринело  већем биосорпционом капацитету.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics, Биосорпција јона никла на тканинама од јуте: кинетичка и  изотермска испитивања",
volume = "86",
number = "9",
pages = "885-897",
doi = "10.2298/JSC210209030I"
}

Ivanovska, A., Pavun, L., Dojčinović, B.,& Kostić, M.. (2021). Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 86(9), 885-897.
https://doi.org/10.2298/JSC210209030I

Ivanovska A, Pavun L, Dojčinović B, Kostić M. Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics. in Journal of the Serbian Chemical Society. 2021;86(9):885-897.
doi:10.2298/JSC210209030I .

Ivanovska, Aleksandra, Pavun, Leposava, Dojčinović, Biljana, Kostić, Mirjana, "Kinetic and isotherm studies for the biosorption of nickel ions by jute fabrics" in Journal of the Serbian Chemical Society, 86, no. 9 (2021):885-897,
https://doi.org/10.2298/JSC210209030I . .

TY  - JOUR
AU  - Ivanovska, Aleksandra
AU  - Lađarević, Jelena
AU  - Pavun, Leposava
AU  - Antonijević, Biljana
AU  - Cvijetić, Ilija
AU  - Mijin, Dušan
AU  - Kostić, Mirjana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3939
AB  - The objective of this investigation was to obtain jute fabrics with enhanced sorption properties (by using simple and cost-effective alkali and oxidative modifications) and a long life cycle. The applied alkali modifications lead to hemicellulose removal and decreased the fibers’ crystallinity, both contributing to enhanced fibers’ sorption properties, i.e., water retention power and degree of fibers’ swelling up to 49 % and 70 %, respectively. A connection between cellulose polymorphs’ (cellulose I and cellulose II) contents (determined by XRD), fibers’ surface morphology (verified by FESEM), fabrics’ crimp, and capillarity of jute fabrics modified with 17.5 % NaOH was established. During the oxidative modifications, significant changes in jute fibers’ chemical composition and structure (i.e., lignin removal and more homogeneous middle lamellae) occurred which further resulted in enhanced jute fabrics’ water retention power and capillarity as well as fibers’ swelling up to 80 %, 75 %, and 54 %, compared to the raw jute, respectively. In order to move towards a circular economy and to ensure the recycling and re-use of recycled fabrics, the jute fabrics with enhanced sorption properties were evaluated as biosorbents for anthraquinone dye C. I. Acid Blue 111. The obtained results revealed that the jute fabrics’ maximum biosorption capacities for this dye ranged from 12.94 to 18.97 mg/g, while the equilibrium adsorption data were highly consistent with the Langmuir isotherm model. Moreover, based on the predicted dye pKa values, the fabric zeta potential, content of carboxyl and aldehyde groups as well as hydrogen bond intensity (determined by ATR-FTIR), a possible mechanism of the dye biosorption onto jute fabric waste was proposed.
PB  - Elsevier B.V.
T2  - Industrial Crops and Products
T1  - Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle
VL  - 171
DO  - 10.1016/j.indcrop.2021.113913
ER  - 

@article{
author = "Ivanovska, Aleksandra and Lađarević, Jelena and Pavun, Leposava and Antonijević, Biljana and Cvijetić, Ilija and Mijin, Dušan and Kostić, Mirjana",
year = "2021",
abstract = "The objective of this investigation was to obtain jute fabrics with enhanced sorption properties (by using simple and cost-effective alkali and oxidative modifications) and a long life cycle. The applied alkali modifications lead to hemicellulose removal and decreased the fibers’ crystallinity, both contributing to enhanced fibers’ sorption properties, i.e., water retention power and degree of fibers’ swelling up to 49 % and 70 %, respectively. A connection between cellulose polymorphs’ (cellulose I and cellulose II) contents (determined by XRD), fibers’ surface morphology (verified by FESEM), fabrics’ crimp, and capillarity of jute fabrics modified with 17.5 % NaOH was established. During the oxidative modifications, significant changes in jute fibers’ chemical composition and structure (i.e., lignin removal and more homogeneous middle lamellae) occurred which further resulted in enhanced jute fabrics’ water retention power and capillarity as well as fibers’ swelling up to 80 %, 75 %, and 54 %, compared to the raw jute, respectively. In order to move towards a circular economy and to ensure the recycling and re-use of recycled fabrics, the jute fabrics with enhanced sorption properties were evaluated as biosorbents for anthraquinone dye C. I. Acid Blue 111. The obtained results revealed that the jute fabrics’ maximum biosorption capacities for this dye ranged from 12.94 to 18.97 mg/g, while the equilibrium adsorption data were highly consistent with the Langmuir isotherm model. Moreover, based on the predicted dye pKa values, the fabric zeta potential, content of carboxyl and aldehyde groups as well as hydrogen bond intensity (determined by ATR-FTIR), a possible mechanism of the dye biosorption onto jute fabric waste was proposed.",
publisher = "Elsevier B.V.",
journal = "Industrial Crops and Products",
title = "Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle",
volume = "171",
doi = "10.1016/j.indcrop.2021.113913"
}

Ivanovska, A., Lađarević, J., Pavun, L., Antonijević, B., Cvijetić, I., Mijin, D.,& Kostić, M.. (2021). Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle. in Industrial Crops and Products
Elsevier B.V.., 171.
https://doi.org/10.1016/j.indcrop.2021.113913

Ivanovska A, Lađarević J, Pavun L, Antonijević B, Cvijetić I, Mijin D, Kostić M. Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle. in Industrial Crops and Products. 2021;171.
doi:10.1016/j.indcrop.2021.113913 .

Ivanovska, Aleksandra, Lađarević, Jelena, Pavun, Leposava, Antonijević, Biljana, Cvijetić, Ilija, Mijin, Dušan, Kostić, Mirjana, "Obtaining jute fabrics with enhanced sorption properties and “closing the loop” of their lifecycle" in Industrial Crops and Products, 171 (2021),
https://doi.org/10.1016/j.indcrop.2021.113913 . .

TY  - JOUR
AU  - Uskoković-Marković, Snežana
AU  - Milenković, Marina
AU  - Pavun, Leposava
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5061
AB  - A B S T R A C T
Flavonoids are a group of polyphenolic compounds widely present in the herbal world and playing an important role in the
human diet. The flavanol quercetin makes up 70% of the total daily intake of flavonoids. Quercetin is able to complex with many
metal ions, and it exhibits potent antioxidative ability. Using the equimolar solution variation method, it was confirmed that
quercetin makes a complex with the zinc(II) ion at pH 5.25, in a stoichiometric ratio quercetin:zinc(II) ion = 2:1, with the
absorption maximum λ=363 nm. This fact was used to develop a simple, precise and accurate assay to determine the content of
quercetin in various samples of heterogeneous composition. The proposed indirect spectrophotometric method can selectively
determine quercetin in concentrations ranging from 0.1 to 6.0 mgL-1, with LOD and LOQ estimated as 0.03 mgL-1 and 0.1 mgL-1,
respectively. The reliability of the proposed method was confirmed by a previously developed RP-HPLC/UV method. The
proposed method was successfully used to determine the quercetin content in dietary supplement tablets, capsules and two
onion extracts, with high reproducibility. The antioxidative ability of quercetin and the zinc(II)-quercetin complex was
determined using DPPH and FRAP methods. The same samples were tested for antimicrobial activity against seven laboratory
control strains of bacteria and one strain of yeast. As a result of those tests, there are no obstacles to combine quercetin and zinc
in the same supplement formulation..
AB  - И З В О Д
Флавоноиди су група полифенолних једињења широко распрострањена у биљном свету, која има значајну улогу у
људској исхрани. Флаванол кверцетин представља око 70% укупног дневног уноса флавоноида. Кверцетин гради
комплексе са бројним металним јонима и поседује значајну антиоксидативну способност. Применом методе варијација
еквимоларних односа, утврђено је да кверцетин гради комплекс са цинк (II) јоном на pH = 5,25, у стехиометријском
односу кверцетин : цинк(II)-јон = 2:1, са апсорпционим максимумом λmax=363 nm. Ова чињеница је искоришћена за
развијање једноставне, прецизне и тачне методе за одређивање кверцетина у различитим узорцима хетерогеног
састава. Предложеним индиректним спектрофотометријским поступком може се селективно одредити кверцетин у
концентрационом опсегу од 0,1 до 6,0 mg L-1, при чему је LOD = 0,03 mg L-1 a LOQ = 0,1 mgL-1. Поузданост предложеног
поступка потврђена је претходно развијеном RP-HPLC / UV методом за метанолне растворе кверцетина и капсула.
Предложена спектрофотометријска метода је успешно примењена за одређивање садржаја кверцетина у дијететским
суплементима, као и у два екстракта лука. Антиоксидативна способност кверцетина и комплекса цинк (II) - кверцетина
одређена је помоћу DPPH и FRAP метода. Такође је испитано антимикробно деловање кверцетина и одговарајућег
комплекса цинка на седам лабораторијских сојева бактерија и један сој квасца. Као резултат ових тестова, нема препрека
да се кверцетин и цинк комбинују у истој дијететској формулацији.
PB  - Faculty of Agronomy Čačak
T2  - Acta Agriculturae Serbica
T1  - Zinc-quercetin complex – from determination to bioactivity
VL  - 25
IS  - 50
SP  - 113
EP  - 120
DO  - 10.5937/AASer2050113U
ER  - 

@article{
author = "Uskoković-Marković, Snežana and Milenković, Marina and Pavun, Leposava",
year = "2020",
abstract = "A B S T R A C T
Flavonoids are a group of polyphenolic compounds widely present in the herbal world and playing an important role in the
human diet. The flavanol quercetin makes up 70% of the total daily intake of flavonoids. Quercetin is able to complex with many
metal ions, and it exhibits potent antioxidative ability. Using the equimolar solution variation method, it was confirmed that
quercetin makes a complex with the zinc(II) ion at pH 5.25, in a stoichiometric ratio quercetin:zinc(II) ion = 2:1, with the
absorption maximum λ=363 nm. This fact was used to develop a simple, precise and accurate assay to determine the content of
quercetin in various samples of heterogeneous composition. The proposed indirect spectrophotometric method can selectively
determine quercetin in concentrations ranging from 0.1 to 6.0 mgL-1, with LOD and LOQ estimated as 0.03 mgL-1 and 0.1 mgL-1,
respectively. The reliability of the proposed method was confirmed by a previously developed RP-HPLC/UV method. The
proposed method was successfully used to determine the quercetin content in dietary supplement tablets, capsules and two
onion extracts, with high reproducibility. The antioxidative ability of quercetin and the zinc(II)-quercetin complex was
determined using DPPH and FRAP methods. The same samples were tested for antimicrobial activity against seven laboratory
control strains of bacteria and one strain of yeast. As a result of those tests, there are no obstacles to combine quercetin and zinc
in the same supplement formulation.., И З В О Д
Флавоноиди су група полифенолних једињења широко распрострањена у биљном свету, која има значајну улогу у
људској исхрани. Флаванол кверцетин представља око 70% укупног дневног уноса флавоноида. Кверцетин гради
комплексе са бројним металним јонима и поседује значајну антиоксидативну способност. Применом методе варијација
еквимоларних односа, утврђено је да кверцетин гради комплекс са цинк (II) јоном на pH = 5,25, у стехиометријском
односу кверцетин : цинк(II)-јон = 2:1, са апсорпционим максимумом λmax=363 nm. Ова чињеница је искоришћена за
развијање једноставне, прецизне и тачне методе за одређивање кверцетина у различитим узорцима хетерогеног
састава. Предложеним индиректним спектрофотометријским поступком може се селективно одредити кверцетин у
концентрационом опсегу од 0,1 до 6,0 mg L-1, при чему је LOD = 0,03 mg L-1 a LOQ = 0,1 mgL-1. Поузданост предложеног
поступка потврђена је претходно развијеном RP-HPLC / UV методом за метанолне растворе кверцетина и капсула.
Предложена спектрофотометријска метода је успешно примењена за одређивање садржаја кверцетина у дијететским
суплементима, као и у два екстракта лука. Антиоксидативна способност кверцетина и комплекса цинк (II) - кверцетина
одређена је помоћу DPPH и FRAP метода. Такође је испитано антимикробно деловање кверцетина и одговарајућег
комплекса цинка на седам лабораторијских сојева бактерија и један сој квасца. Као резултат ових тестова, нема препрека
да се кверцетин и цинк комбинују у истој дијететској формулацији.",
publisher = "Faculty of Agronomy Čačak",
journal = "Acta Agriculturae Serbica",
title = "Zinc-quercetin complex – from determination to bioactivity",
volume = "25",
number = "50",
pages = "113-120",
doi = "10.5937/AASer2050113U"
}

Uskoković-Marković, S., Milenković, M.,& Pavun, L.. (2020). Zinc-quercetin complex – from determination to bioactivity. in Acta Agriculturae Serbica
Faculty of Agronomy Čačak., 25(50), 113-120.
https://doi.org/10.5937/AASer2050113U

Uskoković-Marković S, Milenković M, Pavun L. Zinc-quercetin complex – from determination to bioactivity. in Acta Agriculturae Serbica. 2020;25(50):113-120.
doi:10.5937/AASer2050113U .

Uskoković-Marković, Snežana, Milenković, Marina, Pavun, Leposava, "Zinc-quercetin complex – from determination to bioactivity" in Acta Agriculturae Serbica, 25, no. 50 (2020):113-120,
https://doi.org/10.5937/AASer2050113U . .

TY  - JOUR
AU  - Ivanovska, A.
AU  - Dojčinović, Biljana
AU  - Maletić, S.
AU  - Pavun, Leposava
AU  - Asanović, Koviljka
AU  - Kostić, Mirjana
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3718
AB  - The influence of the chemical composition on the biosorption potential of waste jute fabric for Ni2+, Cu2+, and Zn2+ was investigated. The raw jute fabric was treated with sodium hydroxide or sodium chlorite to selectively remove hemicelluloses and lignin, respectively. All jute fabrics were characterized by determination of their chemical composition as well as functional group content. The effects of solution pH, contact time, and initial metal ion concentration on the biosorption from monometallic and polymetallic solution by jute fabrics were investigated. The maximum biosorption capacity for all heavy metal ions was observed at pH 5.5. Concerning the contact time, the raw jute fabric shows more than 72 % of the total uptake capacity of Ni2+, Cu2+, and Zn2+ within 1 h, while the jute fabrics with lower hemicelluloses and lignin content show between 72–85 % of the total uptake capacity within 3 h. Increased initial metal ion concentration from 10 to 20 mg/l in monometallic solution caused an increase in the total uptake capacity of jute fabrics with lower hemicelluloses and lignin content for 47–69 % (Ni2+), 42–63 % (Cu2+), and 22–37 % (Zn2+). The biosorption capacity of alkali treated jute fabrics was affected by the changes in the total amount of carboxyl and aldehyde groups that accompany the hemicelluloses removal. In the case of the oxidative treatment, the biosorption capacity was affected by the lignin content as well as the amount of introduced carboxyl groups. The best biosorption performance possesses jute fabric with 63.2 % lower lignin content as well as 81.1 % higher amount of carboxyl groups; biosorption capacity toward Ni2+, Cu2+, and Zn2+ in monometallic solution is about 2.4; 2.2 and 3.5 times higher compared to the raw jute fabric, respectively. All jute fabrics exhibited the same affinity order (which is independent on the initial metal ion concentrations) toward heavy metal ions: Ni2+ > Cu2+ > Zn2+ in the case of competitive biosorption. An increase in the initial metal ion concentration for two times in the polymetallic solution caused about a 35–59 % increase in the total uptake capacity of Ni2+, while the total uptake capacities of Cu2+ and Zn2+ increased for 19–38 % and 18–65 %, respectively.
PB  - Korean Fiber Society
T2  - Fibers and Polymers
T1  - Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution
VL  - 21
IS  - 9
SP  - 1992
EP  - 2002
DO  - 10.1007/s12221-020-9639-8
ER  - 

@article{
author = "Ivanovska, A. and Dojčinović, Biljana and Maletić, S. and Pavun, Leposava and Asanović, Koviljka and Kostić, Mirjana",
year = "2020",
abstract = "The influence of the chemical composition on the biosorption potential of waste jute fabric for Ni2+, Cu2+, and Zn2+ was investigated. The raw jute fabric was treated with sodium hydroxide or sodium chlorite to selectively remove hemicelluloses and lignin, respectively. All jute fabrics were characterized by determination of their chemical composition as well as functional group content. The effects of solution pH, contact time, and initial metal ion concentration on the biosorption from monometallic and polymetallic solution by jute fabrics were investigated. The maximum biosorption capacity for all heavy metal ions was observed at pH 5.5. Concerning the contact time, the raw jute fabric shows more than 72 % of the total uptake capacity of Ni2+, Cu2+, and Zn2+ within 1 h, while the jute fabrics with lower hemicelluloses and lignin content show between 72–85 % of the total uptake capacity within 3 h. Increased initial metal ion concentration from 10 to 20 mg/l in monometallic solution caused an increase in the total uptake capacity of jute fabrics with lower hemicelluloses and lignin content for 47–69 % (Ni2+), 42–63 % (Cu2+), and 22–37 % (Zn2+). The biosorption capacity of alkali treated jute fabrics was affected by the changes in the total amount of carboxyl and aldehyde groups that accompany the hemicelluloses removal. In the case of the oxidative treatment, the biosorption capacity was affected by the lignin content as well as the amount of introduced carboxyl groups. The best biosorption performance possesses jute fabric with 63.2 % lower lignin content as well as 81.1 % higher amount of carboxyl groups; biosorption capacity toward Ni2+, Cu2+, and Zn2+ in monometallic solution is about 2.4; 2.2 and 3.5 times higher compared to the raw jute fabric, respectively. All jute fabrics exhibited the same affinity order (which is independent on the initial metal ion concentrations) toward heavy metal ions: Ni2+ > Cu2+ > Zn2+ in the case of competitive biosorption. An increase in the initial metal ion concentration for two times in the polymetallic solution caused about a 35–59 % increase in the total uptake capacity of Ni2+, while the total uptake capacities of Cu2+ and Zn2+ increased for 19–38 % and 18–65 %, respectively.",
publisher = "Korean Fiber Society",
journal = "Fibers and Polymers",
title = "Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution",
volume = "21",
number = "9",
pages = "1992-2002",
doi = "10.1007/s12221-020-9639-8"
}

Ivanovska, A., Dojčinović, B., Maletić, S., Pavun, L., Asanović, K.,& Kostić, M.. (2020). Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution. in Fibers and Polymers
Korean Fiber Society., 21(9), 1992-2002.
https://doi.org/10.1007/s12221-020-9639-8

Ivanovska A, Dojčinović B, Maletić S, Pavun L, Asanović K, Kostić M. Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution. in Fibers and Polymers. 2020;21(9):1992-2002.
doi:10.1007/s12221-020-9639-8 .

Ivanovska, A., Dojčinović, Biljana, Maletić, S., Pavun, Leposava, Asanović, Koviljka, Kostić, Mirjana, "Waste Jute Fabric as a Biosorbent for Heavy Metal Ions from Aqueous Solution" in Fibers and Polymers, 21, no. 9 (2020):1992-2002,
https://doi.org/10.1007/s12221-020-9639-8 . .

TY  - JOUR
AU  - Ivanovska, A.
AU  - Asanović, Koviljka
AU  - Jankoska, Maja
AU  - Mihajlovski, Katarina
AU  - Pavun, Leposava
AU  - Kostić, Mirjana
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3646
AB  - Abstract: The aim of the present research is first to reduce the jute fabric non-cellulosic components by using different chemical modifications (i.e. alkali and oxidative) and then to analyze their influence on the jute fabric properties. For that purpose, the jute fabrics were characterized in terms of their chemical composition, structural parameters, mechanical properties, volume electrical resistivity, antibacterial activity and biosorption of Zn2+. Moreover, the jute fabrics were functionalized by incorporation of silver ions and the fabrics were evaluated as sorption material with a further perspective of reuse. After the alkali modifications, the hemicelluloses were selectively removed and the fabric structural parameters increased. Alkali modifications under mild conditions (1% NaOH for 30 min and 5% NaOH for 5 min) lead to a decrease, while the most intensive alkali modification (17.5% NaOH for 30 min) contributed to an increase in the volume electrical resistivity and fabric maximum force compared to unmodified fabric. A relationship between the jute fabric chemical composition, crystallinity index, conversion of cellulose I to cellulose II, fabric structural parameters and volume electrical resistivity was found. The oxidations lead to selective lignin removal, which consequently causes a decrease in the volume electrical resistivity and fabric maximum force. Ag+ incorporated in the selected samples decreased their electrical resistivity even further. Following the increased focus on the concept of circular economy and sustainable development goals, the biosorption potential of damaged and waste jute fabrics for Zn2+ was investigated. Jute fabrics with incorporated Ag+ and those obtained after the biosorption of Zn2+ provided maximum bacterial reduction (99.99%) for Escherichia coli and Staphylococcus aureus. The chemically modified jute fabrics can be utilized as carpet backing and protective clothing in environments sensitive to electrical discharges, but also as filters for water disinfection and biosorbents for Zn2+.Graphic abstract: [Figure not available: see fulltext.].
PB  - Springer Nature B.V.
T2  - Cellulose
T1  - Multifunctional jute fabrics obtained by different chemical modifications
VL  - 27
SP  - 8485
EP  - 8502
DO  - 10.1007/s10570-020-03360-x
ER  - 

@article{
author = "Ivanovska, A. and Asanović, Koviljka and Jankoska, Maja and Mihajlovski, Katarina and Pavun, Leposava and Kostić, Mirjana",
year = "2020",
abstract = "Abstract: The aim of the present research is first to reduce the jute fabric non-cellulosic components by using different chemical modifications (i.e. alkali and oxidative) and then to analyze their influence on the jute fabric properties. For that purpose, the jute fabrics were characterized in terms of their chemical composition, structural parameters, mechanical properties, volume electrical resistivity, antibacterial activity and biosorption of Zn2+. Moreover, the jute fabrics were functionalized by incorporation of silver ions and the fabrics were evaluated as sorption material with a further perspective of reuse. After the alkali modifications, the hemicelluloses were selectively removed and the fabric structural parameters increased. Alkali modifications under mild conditions (1% NaOH for 30 min and 5% NaOH for 5 min) lead to a decrease, while the most intensive alkali modification (17.5% NaOH for 30 min) contributed to an increase in the volume electrical resistivity and fabric maximum force compared to unmodified fabric. A relationship between the jute fabric chemical composition, crystallinity index, conversion of cellulose I to cellulose II, fabric structural parameters and volume electrical resistivity was found. The oxidations lead to selective lignin removal, which consequently causes a decrease in the volume electrical resistivity and fabric maximum force. Ag+ incorporated in the selected samples decreased their electrical resistivity even further. Following the increased focus on the concept of circular economy and sustainable development goals, the biosorption potential of damaged and waste jute fabrics for Zn2+ was investigated. Jute fabrics with incorporated Ag+ and those obtained after the biosorption of Zn2+ provided maximum bacterial reduction (99.99%) for Escherichia coli and Staphylococcus aureus. The chemically modified jute fabrics can be utilized as carpet backing and protective clothing in environments sensitive to electrical discharges, but also as filters for water disinfection and biosorbents for Zn2+.Graphic abstract: [Figure not available: see fulltext.].",
publisher = "Springer Nature B.V.",
journal = "Cellulose",
title = "Multifunctional jute fabrics obtained by different chemical modifications",
volume = "27",
pages = "8485-8502",
doi = "10.1007/s10570-020-03360-x"
}

Ivanovska, A., Asanović, K., Jankoska, M., Mihajlovski, K., Pavun, L.,& Kostić, M.. (2020). Multifunctional jute fabrics obtained by different chemical modifications. in Cellulose
Springer Nature B.V.., 27, 8485-8502.
https://doi.org/10.1007/s10570-020-03360-x

Ivanovska A, Asanović K, Jankoska M, Mihajlovski K, Pavun L, Kostić M. Multifunctional jute fabrics obtained by different chemical modifications. in Cellulose. 2020;27:8485-8502.
doi:10.1007/s10570-020-03360-x .

Ivanovska, A., Asanović, Koviljka, Jankoska, Maja, Mihajlovski, Katarina, Pavun, Leposava, Kostić, Mirjana, "Multifunctional jute fabrics obtained by different chemical modifications" in Cellulose, 27 (2020):8485-8502,
https://doi.org/10.1007/s10570-020-03360-x . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Uskoković-Marković, Snežana
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5062
AB  - Hesperidin is the flavonoid heteroside most found in citrus species, such
as grapefruit, lemon and orange. It is applied in the treatment of numerous
cardiovascular diseases, with many products containing hesperidin in
combination with other flavonoid heterosides or vitamin C. The aim of this
study was to develop and validate a simple, rapid and sensitive and lowcost
method for determination of hesperidin in tablets and orange juices.
The developed spectrophotometric method is based on the formation of
the Zn(II)-hesperidin complex in 70 v/v% methanol at pH 3.12, with max of
absorption at λmax= 283 nm. The method of variation of equimolar solutions
confirmed the stoichiometry of the complex as hesperidin: zinc= 2:1.
The stability constant of the complex was obtained by the Bjerrum method
and it is logβ2 = 17.01 at pH 3.12. Linearity range for the developed method
was defined as 0.61-7.32 μg/mL, (confirmed by coefficient of determination,
r2 = 0.9882), while limits of detection and quantification were calculated
as LOD = 0.15 μg/mL and LOQ = 0.45 μg/mL. Fairly high precision of the
method is indicated by low values of CV, varying in the range 0.26-1.23%.
The proposed method fulfills all aimed requirements, and it was successfully
applied for determination of hesperidin in tablets with recovery value 92.2
% and commercially available orange juices.
AB  - Hesperidin je flavonoidni heterozid koji se najčešće nalazi u citrusnim vr-
stama, kao što su grejpfrut, limun i pomorandža. Primenjuje se u lečenju
brojnih kardiovaskularnih bolesti, sa mnogim proizvodima koji sadrže hes-
peridin u kombinaciji sa drugim flavonoidnim heterozidima ili vitaminom
C. Cilj ove studije je razvijanje i primena jednostavne, brze i osetljive, a pri
tome pristupačne metode za određivanje hesperidina u tabletama i sokovi-
ma od pomorandže. Razvijena spektrofotometrijska metoda zasniva se na
formiranju Zn(II)-hesperidin kompleksa u 70 v/v% metanolu pri pH 3,12, sa
maksimumom absorbancije na λ max= 283 nm. Metodom varijacije ekvimo-
larnih rastvora utvrđena je stehiometrija kompleksa hesperidin: cink = 2:1.
Konstanta stabilnosti kompleksa dobijena Bjerumovom metodom iznosi
logβ2 = 17,01 pri pH 3,12. Linearnost razvijene metode utvrđena je u oblasti
0,61 - 7,32 μg/mL, (potvrđeno koeficijentom određivanja, r2 = 0,9882), dok
su izračunati limiti detekcije i kvantifikacije LOD = 0,15 μg/mL i LOQ = 0,45
μg/mL. Na visoku preciznost metode ukazuju niske vrednosti koeficijenata
varijacije (CV je u oblasti 0,26 – 1,23 %). Predložena metoda ispunjava sve
postavljene zahteve i sa uspehom je primenjena za određivanje hesperidina
u tabletama uz recovery vrednost 92,2 % i komercijalno dostupnim sokovi-
ma od pomorandže.
PB  - Društvo za ishranu Srbije, Beograd
T2  - Hrana i ishrana
T1  - Spectrophotometric determination of hesperidin in supplements and orange juices
T1  - Spektrofotometrijsko određivanje hesperidina u suplementima i
sokovima od pomorandže
VL  - 60
IS  - 1
SP  - 18
EP  - 23
DO  - 10.5937/HraIsh1901018P
ER  - 

@article{
author = "Pavun, Leposava and Uskoković-Marković, Snežana",
year = "2019",
abstract = "Hesperidin is the flavonoid heteroside most found in citrus species, such
as grapefruit, lemon and orange. It is applied in the treatment of numerous
cardiovascular diseases, with many products containing hesperidin in
combination with other flavonoid heterosides or vitamin C. The aim of this
study was to develop and validate a simple, rapid and sensitive and lowcost
method for determination of hesperidin in tablets and orange juices.
The developed spectrophotometric method is based on the formation of
the Zn(II)-hesperidin complex in 70 v/v% methanol at pH 3.12, with max of
absorption at λmax= 283 nm. The method of variation of equimolar solutions
confirmed the stoichiometry of the complex as hesperidin: zinc= 2:1.
The stability constant of the complex was obtained by the Bjerrum method
and it is logβ2 = 17.01 at pH 3.12. Linearity range for the developed method
was defined as 0.61-7.32 μg/mL, (confirmed by coefficient of determination,
r2 = 0.9882), while limits of detection and quantification were calculated
as LOD = 0.15 μg/mL and LOQ = 0.45 μg/mL. Fairly high precision of the
method is indicated by low values of CV, varying in the range 0.26-1.23%.
The proposed method fulfills all aimed requirements, and it was successfully
applied for determination of hesperidin in tablets with recovery value 92.2
% and commercially available orange juices., Hesperidin je flavonoidni heterozid koji se najčešće nalazi u citrusnim vr-
stama, kao što su grejpfrut, limun i pomorandža. Primenjuje se u lečenju
brojnih kardiovaskularnih bolesti, sa mnogim proizvodima koji sadrže hes-
peridin u kombinaciji sa drugim flavonoidnim heterozidima ili vitaminom
C. Cilj ove studije je razvijanje i primena jednostavne, brze i osetljive, a pri
tome pristupačne metode za određivanje hesperidina u tabletama i sokovi-
ma od pomorandže. Razvijena spektrofotometrijska metoda zasniva se na
formiranju Zn(II)-hesperidin kompleksa u 70 v/v% metanolu pri pH 3,12, sa
maksimumom absorbancije na λ max= 283 nm. Metodom varijacije ekvimo-
larnih rastvora utvrđena je stehiometrija kompleksa hesperidin: cink = 2:1.
Konstanta stabilnosti kompleksa dobijena Bjerumovom metodom iznosi
logβ2 = 17,01 pri pH 3,12. Linearnost razvijene metode utvrđena je u oblasti
0,61 - 7,32 μg/mL, (potvrđeno koeficijentom određivanja, r2 = 0,9882), dok
su izračunati limiti detekcije i kvantifikacije LOD = 0,15 μg/mL i LOQ = 0,45
μg/mL. Na visoku preciznost metode ukazuju niske vrednosti koeficijenata
varijacije (CV je u oblasti 0,26 – 1,23 %). Predložena metoda ispunjava sve
postavljene zahteve i sa uspehom je primenjena za određivanje hesperidina
u tabletama uz recovery vrednost 92,2 % i komercijalno dostupnim sokovi-
ma od pomorandže.",
publisher = "Društvo za ishranu Srbije, Beograd",
journal = "Hrana i ishrana",
title = "Spectrophotometric determination of hesperidin in supplements and orange juices, Spektrofotometrijsko određivanje hesperidina u suplementima i
sokovima od pomorandže",
volume = "60",
number = "1",
pages = "18-23",
doi = "10.5937/HraIsh1901018P"
}

Pavun, L.,& Uskoković-Marković, S.. (2019). Spectrophotometric determination of hesperidin in supplements and orange juices. in Hrana i ishrana
Društvo za ishranu Srbije, Beograd., 60(1), 18-23.
https://doi.org/10.5937/HraIsh1901018P

Pavun L, Uskoković-Marković S. Spectrophotometric determination of hesperidin in supplements and orange juices. in Hrana i ishrana. 2019;60(1):18-23.
doi:10.5937/HraIsh1901018P .

Pavun, Leposava, Uskoković-Marković, Snežana, "Spectrophotometric determination of hesperidin in supplements and orange juices" in Hrana i ishrana, 60, no. 1 (2019):18-23,
https://doi.org/10.5937/HraIsh1901018P . .

TY  - CONF
AU  - Ivanovska, Aleksandra
AU  - Pavun, Leposava
AU  - Asanović, Koviljka
AU  - Kostić, Mirjana
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5215
AB  - Waste jute fabrics (raw and alkali modified), acquired as waste from different industries
were used as an efficient biosorbent for removal of Cu2+ ions from aqueous solution. All
woven jute fabrics (raw as well as alkali modified) were characterized by determination of
their chemical composition and amount of carboxyl groups. The effect of solution pH,
contact time and initial metal ion concentration on the biosorption were studied. The alkali
modifications lead to hemicelluloses removal and an increased amount of carboxyl groups.
The maximum biosorption capacity for Cu2+ was observed at pH 5.5. Concerning the contact
time, more than 80% of total Cu2+ uptake by the raw jute fabric was removed within 1 h. On
the other hand, in the case of alkali modified jute fabrics, between 70-75% of the total Cu2+
uptake was removed within 3 h. Increased initial ion concentration from 10 to 20 mg/l
caused an increase in the total uptake capacity of alkali modified jute fabrics for 42-55%. It
was found that the biosorption properties of waste jute fabrics are predominantly influenced
by the amount of carboxyl groups, while fabric chemical composition (i.e. hemicelluloses
content) has a secondary role in the biosorption of Cu2+ ions. The best biosorption
performance possesses alkali modified jute fabric with 58% higher amount of carboxyl
groups; its total uptake capacity towards Cu2+ ions (at 20 mg/l) is about 2 times higher
compared to the raw jute fabric.
PB  - Belgrade : Institute of Technical Sciences of SASA
C3  - Eighteenth Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts, December 4-6, 2019, Belgrade, Serbia
T1  - Biosorption of Cu2+ from aqueous solution by alkali modified waste jute woven fabrics
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5215
ER  - 

@conference{
author = "Ivanovska, Aleksandra and Pavun, Leposava and Asanović, Koviljka and Kostić, Mirjana",
year = "2019",
abstract = "Waste jute fabrics (raw and alkali modified), acquired as waste from different industries
were used as an efficient biosorbent for removal of Cu2+ ions from aqueous solution. All
woven jute fabrics (raw as well as alkali modified) were characterized by determination of
their chemical composition and amount of carboxyl groups. The effect of solution pH,
contact time and initial metal ion concentration on the biosorption were studied. The alkali
modifications lead to hemicelluloses removal and an increased amount of carboxyl groups.
The maximum biosorption capacity for Cu2+ was observed at pH 5.5. Concerning the contact
time, more than 80% of total Cu2+ uptake by the raw jute fabric was removed within 1 h. On
the other hand, in the case of alkali modified jute fabrics, between 70-75% of the total Cu2+
uptake was removed within 3 h. Increased initial ion concentration from 10 to 20 mg/l
caused an increase in the total uptake capacity of alkali modified jute fabrics for 42-55%. It
was found that the biosorption properties of waste jute fabrics are predominantly influenced
by the amount of carboxyl groups, while fabric chemical composition (i.e. hemicelluloses
content) has a secondary role in the biosorption of Cu2+ ions. The best biosorption
performance possesses alkali modified jute fabric with 58% higher amount of carboxyl
groups; its total uptake capacity towards Cu2+ ions (at 20 mg/l) is about 2 times higher
compared to the raw jute fabric.",
publisher = "Belgrade : Institute of Technical Sciences of SASA",
journal = "Eighteenth Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts, December 4-6, 2019, Belgrade, Serbia",
title = "Biosorption of Cu2+ from aqueous solution by alkali modified waste jute woven fabrics",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5215"
}

Ivanovska, A., Pavun, L., Asanović, K.,& Kostić, M.. (2019). Biosorption of Cu2+ from aqueous solution by alkali modified waste jute woven fabrics. in Eighteenth Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts, December 4-6, 2019, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of SASA..
https://hdl.handle.net/21.15107/rcub_farfar_5215

Ivanovska A, Pavun L, Asanović K, Kostić M. Biosorption of Cu2+ from aqueous solution by alkali modified waste jute woven fabrics. in Eighteenth Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts, December 4-6, 2019, Belgrade, Serbia. 2019;.
https://hdl.handle.net/21.15107/rcub_farfar_5215 .

Ivanovska, Aleksandra, Pavun, Leposava, Asanović, Koviljka, Kostić, Mirjana, "Biosorption of Cu2+ from aqueous solution by alkali modified waste jute woven fabrics" in Eighteenth Young Researchers’ Conference - Materials Science and Engineering: Program and the Book of Abstracts, December 4-6, 2019, Belgrade, Serbia (2019),
https://hdl.handle.net/21.15107/rcub_farfar_5215 .

TY  - CONF
AU  - Pavun, Leposava
AU  - Mićić, Svetlana
AU  - Janošević-Ležaić, Aleksandra
AU  - Kovačević, Katarina
AU  - Uskoković-Marković, Snežana
AU  - Pejić, Nataša
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5218
AB  - ABSTRACT 
The current research provides the development of the new spectrophotometric 
method for the simple and affordable quercetin quantification. Proposed 
method based on formation of supramolecular assembles of quercetin (Q) and 
cetyl trimethylammonium bromide (CTAB). Under selected experimental 
conditions (l = 378 nm, cCTAB = 2 mM and T = 25 °C), Beer’s law was obeyed 
in the quercetin concentration ranged 2 ¥10-6 - 8¥10-5
 mol dm-3. The method 
sensitivity was 2.1 × 104
 dm2
 mol–1
 (the molar absorptivity) as well as 1¥10-6
mol dm-3 (the limit of detection). The method applicability to the direct Q 
determination in a pharmaceutical formulation (Quercetin+C capsules, 
Twinlab) was demonstrated.
PB  - Society of Physical Chemists of Serbia
C3  - PHYSICAL CHEMISTRY 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry
T1  - Spectrophotometric quantification of quercetine using a micelle system
VL  - II
SP  - 983
EP  - 986
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5218
ER  - 

@conference{
author = "Pavun, Leposava and Mićić, Svetlana and Janošević-Ležaić, Aleksandra and Kovačević, Katarina and Uskoković-Marković, Snežana and Pejić, Nataša",
year = "2018",
abstract = "ABSTRACT 
The current research provides the development of the new spectrophotometric 
method for the simple and affordable quercetin quantification. Proposed 
method based on formation of supramolecular assembles of quercetin (Q) and 
cetyl trimethylammonium bromide (CTAB). Under selected experimental 
conditions (l = 378 nm, cCTAB = 2 mM and T = 25 °C), Beer’s law was obeyed 
in the quercetin concentration ranged 2 ¥10-6 - 8¥10-5
 mol dm-3. The method 
sensitivity was 2.1 × 104
 dm2
 mol–1
 (the molar absorptivity) as well as 1¥10-6
mol dm-3 (the limit of detection). The method applicability to the direct Q 
determination in a pharmaceutical formulation (Quercetin+C capsules, 
Twinlab) was demonstrated.",
publisher = "Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry",
title = "Spectrophotometric quantification of quercetine using a micelle system",
volume = "II",
pages = "983-986",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5218"
}

Pavun, L., Mićić, S., Janošević-Ležaić, A., Kovačević, K., Uskoković-Marković, S.,& Pejić, N.. (2018). Spectrophotometric quantification of quercetine using a micelle system. in PHYSICAL CHEMISTRY 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry
Society of Physical Chemists of Serbia., II, 983-986.
https://hdl.handle.net/21.15107/rcub_farfar_5218

Pavun L, Mićić S, Janošević-Ležaić A, Kovačević K, Uskoković-Marković S, Pejić N. Spectrophotometric quantification of quercetine using a micelle system. in PHYSICAL CHEMISTRY 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry. 2018;II:983-986.
https://hdl.handle.net/21.15107/rcub_farfar_5218 .

Pavun, Leposava, Mićić, Svetlana, Janošević-Ležaić, Aleksandra, Kovačević, Katarina, Uskoković-Marković, Snežana, Pejić, Nataša, "Spectrophotometric quantification of quercetine using a micelle system" in PHYSICAL CHEMISTRY 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry, II (2018):983-986,
https://hdl.handle.net/21.15107/rcub_farfar_5218 .

TY  - CONF
AU  - Janošević-Ležaić, Aleksandra
AU  - Pavun, Leposava
AU  - Đikanović, Danijela
AU  - Goronja, Jelena
AU  - Pejić, Nataša
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5217
AB  - ABSTRACT  Aggregation of the cationic surfactant cetyltrimethylammonium bromide 
(CTAB) in water (W) and acetonitrile-water (ACN-W) mixtures of different 
composition (10-20% (v/v) of ACN) was studied through fluorescence 
measurements. The CTAB critical micellar concentration (CMC) and the 
micelle aggregation number (Nagg) were determined at T = 22.0 °C. It was 
found that for increasing volume ratios of ACN to W, the CMC value attains 
a minimum (1.22 mM) at 15% (v/v) ACN while Nagg is continuously 
decreasing as ACN content in the ACN-W mixture increases. The effect of 
this dipolar aprotic solvent on the CTAB micelle formation can be interpreted 
in terms of its considerably hydrogen bonding ability and influence on balk phase properties (solvophobic effect).
PB  - Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry
T1  - Fluorimetric studies of micellar properties of cetyltrimethylammonium bromide in acetonitrile-water mixture
VL  - II
SP  - 867
EP  - 870
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5217
ER  - 

@conference{
author = "Janošević-Ležaić, Aleksandra and Pavun, Leposava and Đikanović, Danijela and Goronja, Jelena and Pejić, Nataša",
year = "2018",
abstract = "ABSTRACT  Aggregation of the cationic surfactant cetyltrimethylammonium bromide 
(CTAB) in water (W) and acetonitrile-water (ACN-W) mixtures of different 
composition (10-20% (v/v) of ACN) was studied through fluorescence 
measurements. The CTAB critical micellar concentration (CMC) and the 
micelle aggregation number (Nagg) were determined at T = 22.0 °C. It was 
found that for increasing volume ratios of ACN to W, the CMC value attains 
a minimum (1.22 mM) at 15% (v/v) ACN while Nagg is continuously 
decreasing as ACN content in the ACN-W mixture increases. The effect of 
this dipolar aprotic solvent on the CTAB micelle formation can be interpreted 
in terms of its considerably hydrogen bonding ability and influence on balk phase properties (solvophobic effect).",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry",
title = "Fluorimetric studies of micellar properties of cetyltrimethylammonium bromide in acetonitrile-water mixture",
volume = "II",
pages = "867-870",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5217"
}

Janošević-Ležaić, A., Pavun, L., Đikanović, D., Goronja, J.,& Pejić, N.. (2018). Fluorimetric studies of micellar properties of cetyltrimethylammonium bromide in acetonitrile-water mixture. in Physical Chemistry 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry
Society of Physical Chemists of Serbia., II, 867-870.
https://hdl.handle.net/21.15107/rcub_farfar_5217

Janošević-Ležaić A, Pavun L, Đikanović D, Goronja J, Pejić N. Fluorimetric studies of micellar properties of cetyltrimethylammonium bromide in acetonitrile-water mixture. in Physical Chemistry 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry. 2018;II:867-870.
https://hdl.handle.net/21.15107/rcub_farfar_5217 .

Janošević-Ležaić, Aleksandra, Pavun, Leposava, Đikanović, Danijela, Goronja, Jelena, Pejić, Nataša, "Fluorimetric studies of micellar properties of cetyltrimethylammonium bromide in acetonitrile-water mixture" in Physical Chemistry 2018 (Proceedings) 14th International Conference  on Fundamental and Applied Aspects of  Physical Chemistry, II (2018):867-870,
https://hdl.handle.net/21.15107/rcub_farfar_5217 .

TY  - CONF
AU  - Pavun, Leposava
AU  - Ćirić, Andrija
AU  - Milenković, Marina
AU  - Uskoković-Marković, Snežana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5220
AB  - Flavonoids are a group of polyphenolic compounds widely present in the herbal world
representing an important part of human diet. Quercetin, which is a flavanol, makes 70% of total daily
intake of flavonoids. Because of the characteristic chemical structure, quercetin has the ability of
complexing metals and antioxidative ability.
Using equimolar solution variation method it was determined that quercetin makes a complex
with zinc(II)-ion in acidic environment (pH 5.25), in stoichiometric relation quercetin:zinc(II)-ion =
2:1, with absorption maximum on λmax=363 nm. The ability of quercetin to make complex
compounds with zinc(II)-ion was used to develop simple, precise and accurate assay to determine the
content of quercetin in various samples of heterogeneous composition.
The proposed indirect spectrophotometric method can selectively determine quercetin in
concentrations ranging from 0.1 to 6.0 mg/L. LOD and LOQ were derived from the calibration curve
and estimated as 0.03 mg/L and 0.1 mg/L respectively. Developed method is reproductive and
accurate, as indicated by high value of correlation coefficient R=0.99996 and low value of
SD=0.00122. Method was successfully used to determine quercetin content in dietary supplement
tablets. Dietary supplements, proscribed for therapeutic and/or profilactic pruposes, usualy content
quercetin combined with other flavonoids and ascorbic acid. Therefore, it was necessary to test the
selectivity of proposed method.
The reliability of the method was checked out by newly developed RP-HPLC/UV method for
capsules with direct determination of quercetin after separation. The good agreement between the two
methods indicates the applicability of the proposed spectrophotometric method for quercetin
determination in dietary supplement tablets with high reproducibility, and enables direct and simple
determination without its prior extraction from samples.
In addition, the antioxidative ability of quecetin and zinc(II)-quercetin complex was
determined using oxidation-reduction standardized methods DPPH and FRAP. The same samples
were tested for antimicrobial activity against seven laboratory control strains of bacteria and one
yeast. As a result of those tests, there are no obstacles to combine quercetin and zinc in the same
formulation.
PB  - Society of Chemists and Technologists of Macedonia
C3  - 25th Congress of Chemists and Technologists of Macedonia, 19–22 September 2018, Ohrid, R. Macedonia
T1  - Spectrophotometric zinc(II) based determination of quercetin in pharmaceutical formulations
SP  - 119
EP  - 119
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5220
ER  - 

@conference{
author = "Pavun, Leposava and Ćirić, Andrija and Milenković, Marina and Uskoković-Marković, Snežana",
year = "2018",
abstract = "Flavonoids are a group of polyphenolic compounds widely present in the herbal world
representing an important part of human diet. Quercetin, which is a flavanol, makes 70% of total daily
intake of flavonoids. Because of the characteristic chemical structure, quercetin has the ability of
complexing metals and antioxidative ability.
Using equimolar solution variation method it was determined that quercetin makes a complex
with zinc(II)-ion in acidic environment (pH 5.25), in stoichiometric relation quercetin:zinc(II)-ion =
2:1, with absorption maximum on λmax=363 nm. The ability of quercetin to make complex
compounds with zinc(II)-ion was used to develop simple, precise and accurate assay to determine the
content of quercetin in various samples of heterogeneous composition.
The proposed indirect spectrophotometric method can selectively determine quercetin in
concentrations ranging from 0.1 to 6.0 mg/L. LOD and LOQ were derived from the calibration curve
and estimated as 0.03 mg/L and 0.1 mg/L respectively. Developed method is reproductive and
accurate, as indicated by high value of correlation coefficient R=0.99996 and low value of
SD=0.00122. Method was successfully used to determine quercetin content in dietary supplement
tablets. Dietary supplements, proscribed for therapeutic and/or profilactic pruposes, usualy content
quercetin combined with other flavonoids and ascorbic acid. Therefore, it was necessary to test the
selectivity of proposed method.
The reliability of the method was checked out by newly developed RP-HPLC/UV method for
capsules with direct determination of quercetin after separation. The good agreement between the two
methods indicates the applicability of the proposed spectrophotometric method for quercetin
determination in dietary supplement tablets with high reproducibility, and enables direct and simple
determination without its prior extraction from samples.
In addition, the antioxidative ability of quecetin and zinc(II)-quercetin complex was
determined using oxidation-reduction standardized methods DPPH and FRAP. The same samples
were tested for antimicrobial activity against seven laboratory control strains of bacteria and one
yeast. As a result of those tests, there are no obstacles to combine quercetin and zinc in the same
formulation.",
publisher = "Society of Chemists and Technologists of Macedonia",
journal = "25th Congress of Chemists and Technologists of Macedonia, 19–22 September 2018, Ohrid, R. Macedonia",
title = "Spectrophotometric zinc(II) based determination of quercetin in pharmaceutical formulations",
pages = "119-119",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5220"
}

Pavun, L., Ćirić, A., Milenković, M.,& Uskoković-Marković, S.. (2018). Spectrophotometric zinc(II) based determination of quercetin in pharmaceutical formulations. in 25th Congress of Chemists and Technologists of Macedonia, 19–22 September 2018, Ohrid, R. Macedonia
Society of Chemists and Technologists of Macedonia., 119-119.
https://hdl.handle.net/21.15107/rcub_farfar_5220

Pavun L, Ćirić A, Milenković M, Uskoković-Marković S. Spectrophotometric zinc(II) based determination of quercetin in pharmaceutical formulations. in 25th Congress of Chemists and Technologists of Macedonia, 19–22 September 2018, Ohrid, R. Macedonia. 2018;:119-119.
https://hdl.handle.net/21.15107/rcub_farfar_5220 .

Pavun, Leposava, Ćirić, Andrija, Milenković, Marina, Uskoković-Marković, Snežana, "Spectrophotometric zinc(II) based determination of quercetin in pharmaceutical formulations" in 25th Congress of Chemists and Technologists of Macedonia, 19–22 September 2018, Ohrid, R. Macedonia (2018):119-119,
https://hdl.handle.net/21.15107/rcub_farfar_5220 .