TY  - JOUR
AU  - Antonijević, Nebojša
AU  - Mitrović, Predrag
AU  - Gošnjić, Nikola
AU  - Orlić, Dejan
AU  - Kadija, Saša
AU  - Ilić Mostić, Tanja
AU  - Savić, Nebojša
AU  - Birovljev, Ljubica
AU  - Leković, Žaklina
AU  - Matić, Dragan
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5079
AB  - Caesarean section is a challenging intervention in patients treated with dual antiplatelet therapy. We present a case of a 32-year-old pregnant woman experiencing large acute myocardial infarction (MI) of the anterolateral wall, complicated by cardiogenic shock in the 38th week of pregnancy, and treated with drug-eluting stent implantation and dual antiplatelet therapy (DAPT) consisting of aspirin and ticagrelor. Less than 24 h after the MI delivery started, an urgent Caesarean section was indicated. As multiplate aggregometry testing showed a relatively insufficient level of ticagrelor platelet inhibition and a moderate level of aspirin platelet inhibition, a Caesarean section was performed without discontinuation of ticagrelor, which was decided due to the need for emergency surgery. Local hemostatic measures including administration of tranexamic acid were applied. The patient did not experience excessive bleeding. A healthy male baby was born. To the best of our knowledge, this is the first reported case of surgery in pregnant women treated with DAPT without ticagrelor discontinuation.
PB  - MDPI
T2  - Journal of Personalized Medicine
T1  - Successful Caesarean Section on Ticagrelor Treatment One Day after Primary Percutaneous Coronary Intervention
VL  - 13
IS  - 9
DO  - 10.3390/jpm13091344
ER  - 

@article{
author = "Antonijević, Nebojša and Mitrović, Predrag and Gošnjić, Nikola and Orlić, Dejan and Kadija, Saša and Ilić Mostić, Tanja and Savić, Nebojša and Birovljev, Ljubica and Leković, Žaklina and Matić, Dragan",
year = "2023",
abstract = "Caesarean section is a challenging intervention in patients treated with dual antiplatelet therapy. We present a case of a 32-year-old pregnant woman experiencing large acute myocardial infarction (MI) of the anterolateral wall, complicated by cardiogenic shock in the 38th week of pregnancy, and treated with drug-eluting stent implantation and dual antiplatelet therapy (DAPT) consisting of aspirin and ticagrelor. Less than 24 h after the MI delivery started, an urgent Caesarean section was indicated. As multiplate aggregometry testing showed a relatively insufficient level of ticagrelor platelet inhibition and a moderate level of aspirin platelet inhibition, a Caesarean section was performed without discontinuation of ticagrelor, which was decided due to the need for emergency surgery. Local hemostatic measures including administration of tranexamic acid were applied. The patient did not experience excessive bleeding. A healthy male baby was born. To the best of our knowledge, this is the first reported case of surgery in pregnant women treated with DAPT without ticagrelor discontinuation.",
publisher = "MDPI",
journal = "Journal of Personalized Medicine",
title = "Successful Caesarean Section on Ticagrelor Treatment One Day after Primary Percutaneous Coronary Intervention",
volume = "13",
number = "9",
doi = "10.3390/jpm13091344"
}

Antonijević, N., Mitrović, P., Gošnjić, N., Orlić, D., Kadija, S., Ilić Mostić, T., Savić, N., Birovljev, L., Leković, Ž.,& Matić, D.. (2023). Successful Caesarean Section on Ticagrelor Treatment One Day after Primary Percutaneous Coronary Intervention. in Journal of Personalized Medicine
MDPI., 13(9).
https://doi.org/10.3390/jpm13091344

Antonijević N, Mitrović P, Gošnjić N, Orlić D, Kadija S, Ilić Mostić T, Savić N, Birovljev L, Leković Ž, Matić D. Successful Caesarean Section on Ticagrelor Treatment One Day after Primary Percutaneous Coronary Intervention. in Journal of Personalized Medicine. 2023;13(9).
doi:10.3390/jpm13091344 .

Antonijević, Nebojša, Mitrović, Predrag, Gošnjić, Nikola, Orlić, Dejan, Kadija, Saša, Ilić Mostić, Tanja, Savić, Nebojša, Birovljev, Ljubica, Leković, Žaklina, Matić, Dragan, "Successful Caesarean Section on Ticagrelor Treatment One Day after Primary Percutaneous Coronary Intervention" in Journal of Personalized Medicine, 13, no. 9 (2023),
https://doi.org/10.3390/jpm13091344 . .