TY  - JOUR
AU  - Bogavac-Stanojević, Nataša
AU  - Jelić-Ivanović, Zorana
AU  - Đurović, Srđan
AU  - Spasojević-Kalimanovska, Vesna
AU  - Spasić, Slavica
AU  - Kalimanovska-Oštrić, Dimitra
AU  - Memon, Lidija
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/610
AB  - High plasma HDL-cholesterol (HDL-c) is a well-established protective factor in coronary artery disease (CAD). One of its potential protective mechanisms is the inhibition of the cytokine-induced upregulation of expression of cellular adhesion molecules (CAMs). High sCAM levels were found to be associated with low HDL-c in some studies performed mostly in hyperlipidemic subjects, but this association has not yet been investigated in CAD patients. In addition, conflicting results were obtained from in vitro studies that explored the proposed HDL effect on cytokine-induced CAM expression. The aim of the present case-control study was to investigate whether low HDL-c values are associated with CAM overexpression in normolipidemic CAD patients and healthy individuals, matched according to age and gender. Plasma HDL-c, sICAM-1, sVCAM-1, and sE-selectin were measured in 37 normolipidemic patients with angiographically verified coronary artery disease and in 52 healthy normolipidemic subjects. The sCAM values obtained in the subjects (patients or controls) with low HDL-c levels ( lt 1.03 mmol/L) were compared with the values in the subjects with high HDL-c (>= 1.03 mmol/L). No significant difference was found between sICAM-1, sVCAM-1, and E-selectin values obtained in subjects with low and high HDL-c, either among the patients or the healthy controls. In conclusion, low HDL-c levels are not associated with CAM overexpression in normolipidemic CAD patients and healthy subjects.
PB  - International Heart Journal Association, Tokyo
T2  - International Heart Journal
T1  - Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects
VL  - 46
IS  - 4
SP  - 593
EP  - 600
DO  - 10.1536/ihj.46.593
ER  - 

@article{
author = "Bogavac-Stanojević, Nataša and Jelić-Ivanović, Zorana and Đurović, Srđan and Spasojević-Kalimanovska, Vesna and Spasić, Slavica and Kalimanovska-Oštrić, Dimitra and Memon, Lidija",
year = "2005",
abstract = "High plasma HDL-cholesterol (HDL-c) is a well-established protective factor in coronary artery disease (CAD). One of its potential protective mechanisms is the inhibition of the cytokine-induced upregulation of expression of cellular adhesion molecules (CAMs). High sCAM levels were found to be associated with low HDL-c in some studies performed mostly in hyperlipidemic subjects, but this association has not yet been investigated in CAD patients. In addition, conflicting results were obtained from in vitro studies that explored the proposed HDL effect on cytokine-induced CAM expression. The aim of the present case-control study was to investigate whether low HDL-c values are associated with CAM overexpression in normolipidemic CAD patients and healthy individuals, matched according to age and gender. Plasma HDL-c, sICAM-1, sVCAM-1, and sE-selectin were measured in 37 normolipidemic patients with angiographically verified coronary artery disease and in 52 healthy normolipidemic subjects. The sCAM values obtained in the subjects (patients or controls) with low HDL-c levels ( lt 1.03 mmol/L) were compared with the values in the subjects with high HDL-c (>= 1.03 mmol/L). No significant difference was found between sICAM-1, sVCAM-1, and E-selectin values obtained in subjects with low and high HDL-c, either among the patients or the healthy controls. In conclusion, low HDL-c levels are not associated with CAM overexpression in normolipidemic CAD patients and healthy subjects.",
publisher = "International Heart Journal Association, Tokyo",
journal = "International Heart Journal",
title = "Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects",
volume = "46",
number = "4",
pages = "593-600",
doi = "10.1536/ihj.46.593"
}

Bogavac-Stanojević, N., Jelić-Ivanović, Z., Đurović, S., Spasojević-Kalimanovska, V., Spasić, S., Kalimanovska-Oštrić, D.,& Memon, L.. (2005). Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects. in International Heart Journal
International Heart Journal Association, Tokyo., 46(4), 593-600.
https://doi.org/10.1536/ihj.46.593

Bogavac-Stanojević N, Jelić-Ivanović Z, Đurović S, Spasojević-Kalimanovska V, Spasić S, Kalimanovska-Oštrić D, Memon L. Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects. in International Heart Journal. 2005;46(4):593-600.
doi:10.1536/ihj.46.593 .

Bogavac-Stanojević, Nataša, Jelić-Ivanović, Zorana, Đurović, Srđan, Spasojević-Kalimanovska, Vesna, Spasić, Slavica, Kalimanovska-Oštrić, Dimitra, Memon, Lidija, "Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects" in International Heart Journal, 46, no. 4 (2005):593-600,
https://doi.org/10.1536/ihj.46.593 . .

TY  - JOUR
AU  - Bogavac-Stanojević, Nataša
AU  - Đurović, S
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Kalimanovska-Oštrić, Dimitra
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/439
AB  - Transforming growth factor-beta(1) (TGF-beta(1)) is involved in different physiological and pathological processes, including atherogenesis. High plasma lipoprotein(a) (Lp(a)) concentration is an established independent risk factor that may interfere with the plasmin-mediated TGF-beta(1) activation. Both Lp(a) and TGF-beta(1) are thought to influence the expression of cellular adhesion molecules (CAMs), also involved in the process of atherogenesis. Whereas many studies confirmed the association between high plasma Lp(a) levels and coronary artery disease (CAD), conflicting results were obtained in different studies in which the changes of TGF-beta(1) and CAM concentrations in,CAD patients were investigated. The aim of this case-control study was to explore the association of circulating TGF-beta(1), Lp(a) and CAMs (intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin) levels with the occurrence and severity of angiographically assessed coronary artery disease. Plasma TGF-beta(1), Lp(a), ICAM-1, VCAM-1 and E-selectin concentrations were measured in 100 patients with angiographically assessed CAD and 100 healthy blood donors matched according to age and gender. Lp(a) and TGF-beta(1) were significantly higher in patients than in healthy controls (p lt 0.001 and p lt 0.01, respectively), but no significant correlation between the TGF-beta(1) and Lp(a) values was found. The CAM concentrations obtained in CAD patients did not differ significantly as compared with the corresponding values in the controls. None of the measured parameters were influenced by the severity of CAD.
PB  - Walter de Gruyter & Co, Berlin
T2  - Clinical Chemistry and Laboratory Medicine
T1  - Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease
VL  - 41
IS  - 7
SP  - 893
EP  - 898
DO  - 10.1515/CCLM.2003.135
ER  - 

@article{
author = "Bogavac-Stanojević, Nataša and Đurović, S and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Kalimanovska-Oštrić, Dimitra",
year = "2003",
abstract = "Transforming growth factor-beta(1) (TGF-beta(1)) is involved in different physiological and pathological processes, including atherogenesis. High plasma lipoprotein(a) (Lp(a)) concentration is an established independent risk factor that may interfere with the plasmin-mediated TGF-beta(1) activation. Both Lp(a) and TGF-beta(1) are thought to influence the expression of cellular adhesion molecules (CAMs), also involved in the process of atherogenesis. Whereas many studies confirmed the association between high plasma Lp(a) levels and coronary artery disease (CAD), conflicting results were obtained in different studies in which the changes of TGF-beta(1) and CAM concentrations in,CAD patients were investigated. The aim of this case-control study was to explore the association of circulating TGF-beta(1), Lp(a) and CAMs (intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin) levels with the occurrence and severity of angiographically assessed coronary artery disease. Plasma TGF-beta(1), Lp(a), ICAM-1, VCAM-1 and E-selectin concentrations were measured in 100 patients with angiographically assessed CAD and 100 healthy blood donors matched according to age and gender. Lp(a) and TGF-beta(1) were significantly higher in patients than in healthy controls (p lt 0.001 and p lt 0.01, respectively), but no significant correlation between the TGF-beta(1) and Lp(a) values was found. The CAM concentrations obtained in CAD patients did not differ significantly as compared with the corresponding values in the controls. None of the measured parameters were influenced by the severity of CAD.",
publisher = "Walter de Gruyter & Co, Berlin",
journal = "Clinical Chemistry and Laboratory Medicine",
title = "Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease",
volume = "41",
number = "7",
pages = "893-898",
doi = "10.1515/CCLM.2003.135"
}

Bogavac-Stanojević, N., Đurović, S., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V.,& Kalimanovska-Oštrić, D.. (2003). Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease. in Clinical Chemistry and Laboratory Medicine
Walter de Gruyter & Co, Berlin., 41(7), 893-898.
https://doi.org/10.1515/CCLM.2003.135

Bogavac-Stanojević N, Đurović S, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Kalimanovska-Oštrić D. Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease. in Clinical Chemistry and Laboratory Medicine. 2003;41(7):893-898.
doi:10.1515/CCLM.2003.135 .

Bogavac-Stanojević, Nataša, Đurović, S, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Kalimanovska-Oštrić, Dimitra, "Circulating transforming growth factor-beta(1), lipoprotein(a) and cellular adhesion molecules in angiographically assessed coronary artery disease" in Clinical Chemistry and Laboratory Medicine, 41, no. 7 (2003):893-898,
https://doi.org/10.1515/CCLM.2003.135 . .