TY  - JOUR
AU  - Lukačišinová, Anna
AU  - Reissigová, Jindra
AU  - Ortner-Hadžiabdić, Maja
AU  - Brkić, Jovana
AU  - Okuyan, Betul
AU  - Volmer, Daisy
AU  - Tadić, Ivana
AU  - Modamio, Pilar
AU  - Mariño, Eduardo
AU  - Tachkov, Konstantine
AU  - Liperotti, Rosa
AU  - Onder, Graziano
AU  - Finne-Soveri, Harriet
AU  - van Hout, Hein
AU  - Howard, Elizabeth P.
AU  - Fialová, Daniela
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5563
AB  - Background: The use of benzodiazepines (BZDs) in older population is often accompanied by drug-related complications. Inappropriate BZD use significantly alters older adults’ clinical and functional status. This study compares the prevalence, prescribing patterns and factors associated with BZD use in community-dwelling older patients in 7 European countries. Methods: International, cross-sectional study was conducted in community-dwelling older adults (65 +) in the Czech Republic, Serbia, Estonia, Bulgaria, Croatia, Turkey, and Spain between Feb2019 and Mar2020. Structured and standardized questionnaire based on interRAI assessment scales was applied. Logistic regression was used to evaluate factors associated with BZD use. Results: Out of 2,865 older patients (mean age 73.2 years ± 6.8, 61.2% women) 14.9% were BZD users. The highest prevalence of BZD use was identified in Croatia (35.5%), Spain (33.5%) and Serbia (31.3%). The most frequently prescribed BZDs were diazepam (27.9% of 426 BZD users), alprazolam (23.7%), bromazepam (22.8%) and lorazepam (16.7%). Independent factors associated with BZD use were female gender (OR 1.58, 95%CI 1.19–2.10), hyperpolypharmacy (OR 1.97, 95%CI 1.22–3.16), anxiety (OR 4.26, 95%CI 2.86–6.38), sleeping problems (OR 4.47, 95%CI 3.38–5.92), depression (OR 1.95, 95%CI 1.29–2.95), repetitive anxious complaints (OR 1.77, 95%CI 1.29–2.42), problems with syncope (OR 1.78, 95%CI 1.03–3.06), and loss of appetite (OR 0.60, 95%CI 0.38–0.94). In comparison to Croatia, residing in other countries was associated with lower odds of BZD use (ORs varied from 0.49 (95%CI 0.32–0.75) in Spain to 0.01 (95%CI 0.00–0.03) in Turkey), excluding Serbia (OR 1.11, 95%CI 0.79–1.56). Conclusions: Despite well-known negative effects, BZDs are still frequently prescribed in older outpatient population in European countries. Principles of safer geriatric prescribing and effective deprescribing strategies should be individually applied in older BZD users.
PB  - BioMed Central Ltd
T2  - BMC Geriatrics
T1  - Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries
VL  - 24
IS  - 1
DO  - 10.1186/s12877-024-04742-7
ER  - 

@article{
author = "Lukačišinová, Anna and Reissigová, Jindra and Ortner-Hadžiabdić, Maja and Brkić, Jovana and Okuyan, Betul and Volmer, Daisy and Tadić, Ivana and Modamio, Pilar and Mariño, Eduardo and Tachkov, Konstantine and Liperotti, Rosa and Onder, Graziano and Finne-Soveri, Harriet and van Hout, Hein and Howard, Elizabeth P. and Fialová, Daniela",
year = "2024",
abstract = "Background: The use of benzodiazepines (BZDs) in older population is often accompanied by drug-related complications. Inappropriate BZD use significantly alters older adults’ clinical and functional status. This study compares the prevalence, prescribing patterns and factors associated with BZD use in community-dwelling older patients in 7 European countries. Methods: International, cross-sectional study was conducted in community-dwelling older adults (65 +) in the Czech Republic, Serbia, Estonia, Bulgaria, Croatia, Turkey, and Spain between Feb2019 and Mar2020. Structured and standardized questionnaire based on interRAI assessment scales was applied. Logistic regression was used to evaluate factors associated with BZD use. Results: Out of 2,865 older patients (mean age 73.2 years ± 6.8, 61.2% women) 14.9% were BZD users. The highest prevalence of BZD use was identified in Croatia (35.5%), Spain (33.5%) and Serbia (31.3%). The most frequently prescribed BZDs were diazepam (27.9% of 426 BZD users), alprazolam (23.7%), bromazepam (22.8%) and lorazepam (16.7%). Independent factors associated with BZD use were female gender (OR 1.58, 95%CI 1.19–2.10), hyperpolypharmacy (OR 1.97, 95%CI 1.22–3.16), anxiety (OR 4.26, 95%CI 2.86–6.38), sleeping problems (OR 4.47, 95%CI 3.38–5.92), depression (OR 1.95, 95%CI 1.29–2.95), repetitive anxious complaints (OR 1.77, 95%CI 1.29–2.42), problems with syncope (OR 1.78, 95%CI 1.03–3.06), and loss of appetite (OR 0.60, 95%CI 0.38–0.94). In comparison to Croatia, residing in other countries was associated with lower odds of BZD use (ORs varied from 0.49 (95%CI 0.32–0.75) in Spain to 0.01 (95%CI 0.00–0.03) in Turkey), excluding Serbia (OR 1.11, 95%CI 0.79–1.56). Conclusions: Despite well-known negative effects, BZDs are still frequently prescribed in older outpatient population in European countries. Principles of safer geriatric prescribing and effective deprescribing strategies should be individually applied in older BZD users.",
publisher = "BioMed Central Ltd",
journal = "BMC Geriatrics",
title = "Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries",
volume = "24",
number = "1",
doi = "10.1186/s12877-024-04742-7"
}

Lukačišinová, A., Reissigová, J., Ortner-Hadžiabdić, M., Brkić, J., Okuyan, B., Volmer, D., Tadić, I., Modamio, P., Mariño, E., Tachkov, K., Liperotti, R., Onder, G., Finne-Soveri, H., van Hout, H., Howard, E. P.,& Fialová, D.. (2024). Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries. in BMC Geriatrics
BioMed Central Ltd., 24(1).
https://doi.org/10.1186/s12877-024-04742-7

Lukačišinová A, Reissigová J, Ortner-Hadžiabdić M, Brkić J, Okuyan B, Volmer D, Tadić I, Modamio P, Mariño E, Tachkov K, Liperotti R, Onder G, Finne-Soveri H, van Hout H, Howard EP, Fialová D. Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries. in BMC Geriatrics. 2024;24(1).
doi:10.1186/s12877-024-04742-7 .

Lukačišinová, Anna, Reissigová, Jindra, Ortner-Hadžiabdić, Maja, Brkić, Jovana, Okuyan, Betul, Volmer, Daisy, Tadić, Ivana, Modamio, Pilar, Mariño, Eduardo, Tachkov, Konstantine, Liperotti, Rosa, Onder, Graziano, Finne-Soveri, Harriet, van Hout, Hein, Howard, Elizabeth P., Fialová, Daniela, "Prevalence, country-specific prescribing patterns and determinants of benzodiazepine use in community-residing older adults in 7 European countries" in BMC Geriatrics, 24, no. 1 (2024),
https://doi.org/10.1186/s12877-024-04742-7 . .

TY  - JOUR
AU  - Costa, Filipa Alves
AU  - Scullin, Claire
AU  - Al-Taani, Ghaith
AU  - Hawwa, Ahmed F
AU  - Anderson, Claire
AU  - Bezverhni, Zinaida
AU  - Binakaj, Zahida
AU  - Cordina, Maria
AU  - Foulon, Veerle
AU  - Garcia de Bikuña, Borja
AU  - de Gier, Han
AU  - Gerd Granås, Anne
AU  - Grinstova, Olga
AU  - Griese-Mammen, Nina
AU  - Grincevicius, Jonas
AU  - Grinceviciene, Svitrigaile
AU  - Kaae, Susanne
AU  - Kubiliene, Loreta
AU  - Mariño, Eduardo L
AU  - Martins, Silvia
AU  - Modamio, Pilar
AU  - Nadin, Giancarlo
AU  - Stig Nørgaard, Lotte
AU  - Obarcanin, Emina
AU  - Tadić, Ivana
AU  - Tasić, Ljiljana
AU  - McElnay, James C
AU  - Hersberger, Kurt E
AU  - Westerlund, Tommy
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4211
AB  - Rationale, aims, and objectives: Pharmaceutical care involves patient-centred pharmacist activity to improve medicines management by patients. The implementation of this service in a comprehensive manner, however, requires considerable organisation and effort, and indeed, it is often not fully implemented in care settings. The main objective was to assess how pharmaceutical care provision within community pharmacy has evolved over time in Europe.

Method: A cross-sectional questionnaire-based survey of community pharmacies, using a modified version of the Behavioural Pharmaceutical Care Scale (BPCS) was conducted in late 2012/early 2013 within 16 European countries and compared with an earlier assessment conducted in 2006.

Results: The provision of comprehensive pharmaceutical care has slightly improved in all European countries that participated in both editions of this survey (n = 8) with progress being made particularly in Denmark and Switzerland. Moreover, there was a wider country uptake, indicating spread of the concept. However, due to a number of limitations, the results should be interpreted with caution. Using combined data from participating countries, the provision of pharmaceutical care was positively correlated with the participation of the community pharmacists in patient-centred activities, routine use of pharmacy software with access to clinical data, participation in multidisciplinary team meetings, and having specialized education.

Conclusions: The present study demonstrated a slight evolution in self-reported provision of pharmaceutical care by community pharmacists across Europe, as measured by the BPCS. The slow progress suggests a range of barriers, which are preventing pharmacists moving beyond traditional roles. Support from professional bodies and more patient-centred community pharmacy contracts, including remuneration for pharmaceutical care services, are likely to be required if quicker progress is to be made in the future.
PB  - Wiley
T2  - Journal of evaluation in clinical practice
T1  - Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?
VL  - 23
IS  - 6
SP  - 1336
EP  - 1347
DO  - 10.1111/jep.12783
ER  - 

@article{
author = "Costa, Filipa Alves and Scullin, Claire and Al-Taani, Ghaith and Hawwa, Ahmed F and Anderson, Claire and Bezverhni, Zinaida and Binakaj, Zahida and Cordina, Maria and Foulon, Veerle and Garcia de Bikuña, Borja and de Gier, Han and Gerd Granås, Anne and Grinstova, Olga and Griese-Mammen, Nina and Grincevicius, Jonas and Grinceviciene, Svitrigaile and Kaae, Susanne and Kubiliene, Loreta and Mariño, Eduardo L and Martins, Silvia and Modamio, Pilar and Nadin, Giancarlo and Stig Nørgaard, Lotte and Obarcanin, Emina and Tadić, Ivana and Tasić, Ljiljana and McElnay, James C and Hersberger, Kurt E and Westerlund, Tommy",
year = "2017",
abstract = "Rationale, aims, and objectives: Pharmaceutical care involves patient-centred pharmacist activity to improve medicines management by patients. The implementation of this service in a comprehensive manner, however, requires considerable organisation and effort, and indeed, it is often not fully implemented in care settings. The main objective was to assess how pharmaceutical care provision within community pharmacy has evolved over time in Europe.

Method: A cross-sectional questionnaire-based survey of community pharmacies, using a modified version of the Behavioural Pharmaceutical Care Scale (BPCS) was conducted in late 2012/early 2013 within 16 European countries and compared with an earlier assessment conducted in 2006.

Results: The provision of comprehensive pharmaceutical care has slightly improved in all European countries that participated in both editions of this survey (n = 8) with progress being made particularly in Denmark and Switzerland. Moreover, there was a wider country uptake, indicating spread of the concept. However, due to a number of limitations, the results should be interpreted with caution. Using combined data from participating countries, the provision of pharmaceutical care was positively correlated with the participation of the community pharmacists in patient-centred activities, routine use of pharmacy software with access to clinical data, participation in multidisciplinary team meetings, and having specialized education.

Conclusions: The present study demonstrated a slight evolution in self-reported provision of pharmaceutical care by community pharmacists across Europe, as measured by the BPCS. The slow progress suggests a range of barriers, which are preventing pharmacists moving beyond traditional roles. Support from professional bodies and more patient-centred community pharmacy contracts, including remuneration for pharmaceutical care services, are likely to be required if quicker progress is to be made in the future.",
publisher = "Wiley",
journal = "Journal of evaluation in clinical practice",
title = "Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?",
volume = "23",
number = "6",
pages = "1336-1347",
doi = "10.1111/jep.12783"
}

Costa, F. A., Scullin, C., Al-Taani, G., Hawwa, A. F., Anderson, C., Bezverhni, Z., Binakaj, Z., Cordina, M., Foulon, V., Garcia de Bikuña, B., de Gier, H., Gerd Granås, A., Grinstova, O., Griese-Mammen, N., Grincevicius, J., Grinceviciene, S., Kaae, S., Kubiliene, L., Mariño, E. L., Martins, S., Modamio, P., Nadin, G., Stig Nørgaard, L., Obarcanin, E., Tadić, I., Tasić, L., McElnay, J. C., Hersberger, K. E.,& Westerlund, T.. (2017). Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?. in Journal of evaluation in clinical practice
Wiley., 23(6), 1336-1347.
https://doi.org/10.1111/jep.12783

Costa FA, Scullin C, Al-Taani G, Hawwa AF, Anderson C, Bezverhni Z, Binakaj Z, Cordina M, Foulon V, Garcia de Bikuña B, de Gier H, Gerd Granås A, Grinstova O, Griese-Mammen N, Grincevicius J, Grinceviciene S, Kaae S, Kubiliene L, Mariño EL, Martins S, Modamio P, Nadin G, Stig Nørgaard L, Obarcanin E, Tadić I, Tasić L, McElnay JC, Hersberger KE, Westerlund T. Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?. in Journal of evaluation in clinical practice. 2017;23(6):1336-1347.
doi:10.1111/jep.12783 .

Costa, Filipa Alves, Scullin, Claire, Al-Taani, Ghaith, Hawwa, Ahmed F, Anderson, Claire, Bezverhni, Zinaida, Binakaj, Zahida, Cordina, Maria, Foulon, Veerle, Garcia de Bikuña, Borja, de Gier, Han, Gerd Granås, Anne, Grinstova, Olga, Griese-Mammen, Nina, Grincevicius, Jonas, Grinceviciene, Svitrigaile, Kaae, Susanne, Kubiliene, Loreta, Mariño, Eduardo L, Martins, Silvia, Modamio, Pilar, Nadin, Giancarlo, Stig Nørgaard, Lotte, Obarcanin, Emina, Tadić, Ivana, Tasić, Ljiljana, McElnay, James C, Hersberger, Kurt E, Westerlund, Tommy, "Provision of pharmaceutical care by community pharmacists across Europe: Is it developing and spreading?" in Journal of evaluation in clinical practice, 23, no. 6 (2017):1336-1347,
https://doi.org/10.1111/jep.12783 . .