Stojković, Tatjana

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orcid::0000-0002-8570-5135
  • Stojković, Tatjana (11)
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Author's Bibliography

Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents

Marinković, Valentina; Stojković, Tatjana; Zeković, Milica; Tasić, Ljiljana; Krajnović, Dušanka

(Association of Pharmaceutical Teachers of India, 2020)

TY  - JOUR
AU  - Marinković, Valentina
AU  - Stojković, Tatjana
AU  - Zeković, Milica
AU  - Tasić, Ljiljana
AU  - Krajnović, Dušanka
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3498
AB  - Background: Medicines dispensing is an error-prone activity, therefore potentially jeopardizing patient safety. This study aimed to assess the community pharmacists’ attitudes towards the causes of dispensing errors and preventive measures, as well as their practice in incidents reporting. Materials and Methods: A cross-sectional survey was performed by distributing an adopted and validated questionnaire to a nationwide sample of community pharmacists in Serbia. The questionnaire included sections related to the participants’ socio-demographic characteristics, their attitudes towards factors causing dispensing errors and corrective actions, as well as their practice in reporting. Statistical analyses were conducted using SPSS Statistics software ver. 21.0. The associations between categorical variables were analyzed using Chi-square test. Results: The study included 1,004 participants, mainly female (94.9%), with the mean age 40.9±9.9 years and mean work experience 14.3±10.0 years. More than a third of the participants (35.4%) indicated an increasing risk of dispensing errors. The main causes included illegible prescriber‘s handwriting (44.3%) and interruptions during dispensing (39.2%), while the major corrective actions were providing pharmacists with education in clinical pharmacy (71%) and reducing the interruptions during dispensing (63.9%). The majority of respondents (85.2%) stated that they routinely reported dispensing incidents. However, even 16.5% of them admitted to having fear sometimes or always. Additionally, only 58.1% of participants would use voluntary dispensing error reporting system. Conclusion: Serbian community pharmacists are aware of the existing risk in medicines dispensing and the corrective actions identified should be put into practice so as to manage them prospectively. Although the results indicate good practice in incidents reporting, conducting tailored educations and building of safety culture is necessary to improve patient safety.
PB  - Association of Pharmaceutical Teachers of India
T2  - Indian Journal of Pharmaceutical Education and Research
T1  - Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents
VL  - 54
IS  - 1
SP  - 194
EP  - 205
DO  - 10.5530/ijper.54.1.23
ER  - 
@article{
author = "Marinković, Valentina and Stojković, Tatjana and Zeković, Milica and Tasić, Ljiljana and Krajnović, Dušanka",
year = "2020",
abstract = "Background: Medicines dispensing is an error-prone activity, therefore potentially jeopardizing patient safety. This study aimed to assess the community pharmacists’ attitudes towards the causes of dispensing errors and preventive measures, as well as their practice in incidents reporting. Materials and Methods: A cross-sectional survey was performed by distributing an adopted and validated questionnaire to a nationwide sample of community pharmacists in Serbia. The questionnaire included sections related to the participants’ socio-demographic characteristics, their attitudes towards factors causing dispensing errors and corrective actions, as well as their practice in reporting. Statistical analyses were conducted using SPSS Statistics software ver. 21.0. The associations between categorical variables were analyzed using Chi-square test. Results: The study included 1,004 participants, mainly female (94.9%), with the mean age 40.9±9.9 years and mean work experience 14.3±10.0 years. More than a third of the participants (35.4%) indicated an increasing risk of dispensing errors. The main causes included illegible prescriber‘s handwriting (44.3%) and interruptions during dispensing (39.2%), while the major corrective actions were providing pharmacists with education in clinical pharmacy (71%) and reducing the interruptions during dispensing (63.9%). The majority of respondents (85.2%) stated that they routinely reported dispensing incidents. However, even 16.5% of them admitted to having fear sometimes or always. Additionally, only 58.1% of participants would use voluntary dispensing error reporting system. Conclusion: Serbian community pharmacists are aware of the existing risk in medicines dispensing and the corrective actions identified should be put into practice so as to manage them prospectively. Although the results indicate good practice in incidents reporting, conducting tailored educations and building of safety culture is necessary to improve patient safety.",
publisher = "Association of Pharmaceutical Teachers of India",
journal = "Indian Journal of Pharmaceutical Education and Research",
title = "Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents",
volume = "54",
number = "1",
pages = "194-205",
doi = "10.5530/ijper.54.1.23"
}
Marinković, V., Stojković, T., Zeković, M., Tasić, L.,& Krajnović, D.. (2020). Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents. in Indian Journal of Pharmaceutical Education and Research
Association of Pharmaceutical Teachers of India., 54(1), 194-205.
https://doi.org/10.5530/ijper.54.1.23
Marinković V, Stojković T, Zeković M, Tasić L, Krajnović D. Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents. in Indian Journal of Pharmaceutical Education and Research. 2020;54(1):194-205.
doi:10.5530/ijper.54.1.23 .
Marinković, Valentina, Stojković, Tatjana, Zeković, Milica, Tasić, Ljiljana, Krajnović, Dušanka, "Community pharmacists’ attitudes and professional practice in relation to the patient safety incidents" in Indian Journal of Pharmaceutical Education and Research, 54, no. 1 (2020):194-205,
https://doi.org/10.5530/ijper.54.1.23 . .
1
2
1

Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies

Stojković, Tatjana; Rose, Olaf; Woltersdorf, Ronja; Marinković, Valentina; Manser, Tanja; Jaehde, Ulrich

(Springer, Dordrecht, 2018)

TY  - CONF
AU  - Stojković, Tatjana
AU  - Rose, Olaf
AU  - Woltersdorf, Ronja
AU  - Marinković, Valentina
AU  - Manser, Tanja
AU  - Jaehde, Ulrich
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3180
PB  - Springer, Dordrecht
C3  - International Journal of Clinical Pharmacy
T1  - Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies
VL  - 40
IS  - 1
SP  - 215
EP  - 215
DO  - 10.1007/s11096-017-0565-9
ER  - 
@conference{
author = "Stojković, Tatjana and Rose, Olaf and Woltersdorf, Ronja and Marinković, Valentina and Manser, Tanja and Jaehde, Ulrich",
year = "2018",
publisher = "Springer, Dordrecht",
journal = "International Journal of Clinical Pharmacy",
title = "Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies",
volume = "40",
number = "1",
pages = "215-215",
doi = "10.1007/s11096-017-0565-9"
}
Stojković, T., Rose, O., Woltersdorf, R., Marinković, V., Manser, T.,& Jaehde, U.. (2018). Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies. in International Journal of Clinical Pharmacy
Springer, Dordrecht., 40(1), 215-215.
https://doi.org/10.1007/s11096-017-0565-9
Stojković T, Rose O, Woltersdorf R, Marinković V, Manser T, Jaehde U. Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies. in International Journal of Clinical Pharmacy. 2018;40(1):215-215.
doi:10.1007/s11096-017-0565-9 .
Stojković, Tatjana, Rose, Olaf, Woltersdorf, Ronja, Marinković, Valentina, Manser, Tanja, Jaehde, Ulrich, "Failure mode and effects analysis: a useful tool for prospective risk assessment in community pharmacies" in International Journal of Clinical Pharmacy, 40, no. 1 (2018):215-215,
https://doi.org/10.1007/s11096-017-0565-9 . .
7

Prospective systemic risk analysis of the dispensing process in German community pharmacies

Stojković, Tatjana; Rose, Olaf; Woltersdorf, Ronja; Marinković, Valentina; Manser, Tanja; Jaehde, Ulrich

(Wiley, Hoboken, 2018)

TY  - JOUR
AU  - Stojković, Tatjana
AU  - Rose, Olaf
AU  - Woltersdorf, Ronja
AU  - Marinković, Valentina
AU  - Manser, Tanja
AU  - Jaehde, Ulrich
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3181
AB  - BackgroundMedicine dispensing represents an error-prone activity, carrying a considerable risk for patients. ObjectiveTo prospectively identify and prioritize potential failure modes in the medicine dispensing process as well as to develop corrective actions for patient safety improvement in German community pharmacies. MethodFailure mode and effects analysis was performed in 2 community pharmacies in North Rhine-Westphalia, Germany, in October 2016. A 9-member team was assembled, comprising of a leader and process experts who prospectively assessed the medicine dispensing process by brainstorming, quantified the attributed risks, proposed corrective actions, and reassessed the risks. ResultsThe analysis identified 39 failure modes, out of which the highest criticality scores were assigned to inadequate assessment of therapy appropriateness (Risk Priority Number 45), reluctance to deviate from rebate contracts (36), and dispensing the wrong medicine (30). The corrective actions proposed demonstrated a considerable potential for risk reduction in most failure modes, the most effective of which were introducing obligatory continuous education for pharmacists, organizing communication training, and implementing electronic prescribing. ConclusionThis analysis not only detected various potential safety issues concerning the dispensing in Germany but also strongly indicated that application of failure mode and effects analysis could be highly effective in prospective risk reduction in community pharmacies.
PB  - Wiley, Hoboken
T2  - International Journal of Health Planning and Management
T1  - Prospective systemic risk analysis of the dispensing process in German community pharmacies
VL  - 33
IS  - 1
DO  - 10.1002/hpm.2479
ER  - 
@article{
author = "Stojković, Tatjana and Rose, Olaf and Woltersdorf, Ronja and Marinković, Valentina and Manser, Tanja and Jaehde, Ulrich",
year = "2018",
abstract = "BackgroundMedicine dispensing represents an error-prone activity, carrying a considerable risk for patients. ObjectiveTo prospectively identify and prioritize potential failure modes in the medicine dispensing process as well as to develop corrective actions for patient safety improvement in German community pharmacies. MethodFailure mode and effects analysis was performed in 2 community pharmacies in North Rhine-Westphalia, Germany, in October 2016. A 9-member team was assembled, comprising of a leader and process experts who prospectively assessed the medicine dispensing process by brainstorming, quantified the attributed risks, proposed corrective actions, and reassessed the risks. ResultsThe analysis identified 39 failure modes, out of which the highest criticality scores were assigned to inadequate assessment of therapy appropriateness (Risk Priority Number 45), reluctance to deviate from rebate contracts (36), and dispensing the wrong medicine (30). The corrective actions proposed demonstrated a considerable potential for risk reduction in most failure modes, the most effective of which were introducing obligatory continuous education for pharmacists, organizing communication training, and implementing electronic prescribing. ConclusionThis analysis not only detected various potential safety issues concerning the dispensing in Germany but also strongly indicated that application of failure mode and effects analysis could be highly effective in prospective risk reduction in community pharmacies.",
publisher = "Wiley, Hoboken",
journal = "International Journal of Health Planning and Management",
title = "Prospective systemic risk analysis of the dispensing process in German community pharmacies",
volume = "33",
number = "1",
doi = "10.1002/hpm.2479"
}
Stojković, T., Rose, O., Woltersdorf, R., Marinković, V., Manser, T.,& Jaehde, U.. (2018). Prospective systemic risk analysis of the dispensing process in German community pharmacies. in International Journal of Health Planning and Management
Wiley, Hoboken., 33(1).
https://doi.org/10.1002/hpm.2479
Stojković T, Rose O, Woltersdorf R, Marinković V, Manser T, Jaehde U. Prospective systemic risk analysis of the dispensing process in German community pharmacies. in International Journal of Health Planning and Management. 2018;33(1).
doi:10.1002/hpm.2479 .
Stojković, Tatjana, Rose, Olaf, Woltersdorf, Ronja, Marinković, Valentina, Manser, Tanja, Jaehde, Ulrich, "Prospective systemic risk analysis of the dispensing process in German community pharmacies" in International Journal of Health Planning and Management, 33, no. 1 (2018),
https://doi.org/10.1002/hpm.2479 . .
6
1
7

Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies

Stojković, Tatjana; Marinković, Valentina; Manser, Tanja; Woltersdorf, Ronja; Rose, Olaf; Jaehde, Ulrich

(Springer, 2017)

TY  - CONF
AU  - Stojković, Tatjana
AU  - Marinković, Valentina
AU  - Manser, Tanja
AU  - Woltersdorf, Ronja
AU  - Rose, Olaf
AU  - Jaehde, Ulrich
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3029
PB  - Springer
C3  - International Journal of Clinical Pharmacy
T1  - Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies
VL  - 39
IS  - 3
SP  - 605
EP  - 606
DO  - 10.1007/s11096-017-0462-2
ER  - 
@conference{
author = "Stojković, Tatjana and Marinković, Valentina and Manser, Tanja and Woltersdorf, Ronja and Rose, Olaf and Jaehde, Ulrich",
year = "2017",
publisher = "Springer",
journal = "International Journal of Clinical Pharmacy",
title = "Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies",
volume = "39",
number = "3",
pages = "605-606",
doi = "10.1007/s11096-017-0462-2"
}
Stojković, T., Marinković, V., Manser, T., Woltersdorf, R., Rose, O.,& Jaehde, U.. (2017). Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies. in International Journal of Clinical Pharmacy
Springer., 39(3), 605-606.
https://doi.org/10.1007/s11096-017-0462-2
Stojković T, Marinković V, Manser T, Woltersdorf R, Rose O, Jaehde U. Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies. in International Journal of Clinical Pharmacy. 2017;39(3):605-606.
doi:10.1007/s11096-017-0462-2 .
Stojković, Tatjana, Marinković, Valentina, Manser, Tanja, Woltersdorf, Ronja, Rose, Olaf, Jaehde, Ulrich, "Comparing findings from prospective risk analyses of the dispensing processes in Serbian and German community pharmacies" in International Journal of Clinical Pharmacy, 39, no. 3 (2017):605-606,
https://doi.org/10.1007/s11096-017-0462-2 . .
6

Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal

Stojković, Tatjana; Marinković, Valentina; Manser, Tanja

(Lippincott Williams and Wilkins, 2017)

TY  - JOUR
AU  - Stojković, Tatjana
AU  - Marinković, Valentina
AU  - Manser, Tanja
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2978
AB  - OBJECTIVES: This study aimed to review and critically appraise the published literature on 2 selected prospective risk analysis tools, Failure Mode and Effects Analysis and Socio-Technical Probabilistic Risk Assessment, as applied to the dispensing of medicines in both inpatient and outpatient pharmacy settings. METHODS: A comprehensive search of electronic databases (PubMed and Scopus) was conducted (January 1990–March 2016), supplemented by hand search of reference lists. Eligible articles were assessed for data sources used for the risk analysis, uniformity of the risk quantification framework, and whether the analysis teams assembled were multidisciplinary. RESULTS: Of 1011 records identified, 11 articles met our inclusion criteria. These studies were mainly focused on dispensing of high-alert medications, and most were conducted in inpatient settings. The main risks identified were transcription, preparation, and selection errors, whereas the most common corrective actions included electronic transmission of prescriptions to the pharmacy, use of barcode, and medication safety training. Significant risk reduction was demonstrated by implementing corrective measures in both inpatient and outpatient pharmacy settings. The main Failure Mode and Effects Analysis limitations were its subjectivity and the lack of common risk quantification criteria. CONCLUSIONS: The prospective risk analysis methods included in this review revealed relevant safety issues and hold significant potential for risk reduction. They were deemed suitable for application in both inpatient and outpatient pharmacy settings and should form an integral part of any patient safety improvement strategy
PB  - Lippincott Williams and Wilkins
T2  - Journal of Patient Safety
T1  - Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal
DO  - 10.1097/PTS.0000000000000403
ER  - 
@article{
author = "Stojković, Tatjana and Marinković, Valentina and Manser, Tanja",
year = "2017",
abstract = "OBJECTIVES: This study aimed to review and critically appraise the published literature on 2 selected prospective risk analysis tools, Failure Mode and Effects Analysis and Socio-Technical Probabilistic Risk Assessment, as applied to the dispensing of medicines in both inpatient and outpatient pharmacy settings. METHODS: A comprehensive search of electronic databases (PubMed and Scopus) was conducted (January 1990–March 2016), supplemented by hand search of reference lists. Eligible articles were assessed for data sources used for the risk analysis, uniformity of the risk quantification framework, and whether the analysis teams assembled were multidisciplinary. RESULTS: Of 1011 records identified, 11 articles met our inclusion criteria. These studies were mainly focused on dispensing of high-alert medications, and most were conducted in inpatient settings. The main risks identified were transcription, preparation, and selection errors, whereas the most common corrective actions included electronic transmission of prescriptions to the pharmacy, use of barcode, and medication safety training. Significant risk reduction was demonstrated by implementing corrective measures in both inpatient and outpatient pharmacy settings. The main Failure Mode and Effects Analysis limitations were its subjectivity and the lack of common risk quantification criteria. CONCLUSIONS: The prospective risk analysis methods included in this review revealed relevant safety issues and hold significant potential for risk reduction. They were deemed suitable for application in both inpatient and outpatient pharmacy settings and should form an integral part of any patient safety improvement strategy",
publisher = "Lippincott Williams and Wilkins",
journal = "Journal of Patient Safety",
title = "Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal",
doi = "10.1097/PTS.0000000000000403"
}
Stojković, T., Marinković, V.,& Manser, T.. (2017). Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal. in Journal of Patient Safety
Lippincott Williams and Wilkins..
https://doi.org/10.1097/PTS.0000000000000403
Stojković T, Marinković V, Manser T. Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal. in Journal of Patient Safety. 2017;.
doi:10.1097/PTS.0000000000000403 .
Stojković, Tatjana, Marinković, Valentina, Manser, Tanja, "Using Prospective Risk Analysis Tools to Improve Safety in Pharmacy Settings: A Systematic Review and Critical Appraisal" in Journal of Patient Safety (2017),
https://doi.org/10.1097/PTS.0000000000000403 . .
3
6
1
2

Patient safety and medication errors in the provision of health care services-challenges for contemporary practice

Stojković, Tatjana; Marinković, Valentina; Krajnović, Dušanka; Tasić, Ljiljana; Milošević-Georgiev, Andrijana

(Univerzitet u Nišu - Medicinski fakultet, Niš, 2016)

TY  - JOUR
AU  - Stojković, Tatjana
AU  - Marinković, Valentina
AU  - Krajnović, Dušanka
AU  - Tasić, Ljiljana
AU  - Milošević-Georgiev, Andrijana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2764
AB  - Non-maleficence represents one of the basic ethical principles that health care providers should be guided by during service delivery. Establishment of patient safety is nowadays recognized as an issue of global concern in health care and a critical component of quality management. The aim of this paper is to provide a literature review of the patient safety and medication errors concept, with special attention given to defining the most significant terms, analyzing the causal factors and reviewing their classification. Raising awareness about the importance of patient safety has resulted in an increase in the number of medication error studies over the last decade. The traditional approach which makes health workers responsible for reduction of incidents is replaced by the modern concept which implies the involvement of all stakeholders at all levels of the system. In developed countries, the application of prospective risk management models for specific health care processes has already started. However, all these studies are mainly carried out at the secondary and tertiary levels of health care, while they are almost non-existent at the primary level. In the Republic of Serbia, a Rulebook on indicators of the quality of health care has been recently adopted, but a trend of significant lack of data regarding patient safety can be noticed due to inadequate reporting. It is necessary to continue with the homogenization of terminology and to increase the number of analyses of causal factors with the aim of prospective risk identification, particularly in developing countries such as the Republic of Serbia.
AB  - Neškodljivost predstavlja jedan od osnovnih etičkih principa kojim bi trebalo da se rukovode zdravstveni radnici prilikom pružanja usluga zdravstvene zaštite. Uspostavljanje i unapređenje bezbednosti bolesnika danas je prepoznato kao problem od globalnog značaja u zdravstvu i kritična komponenta upravljanja kvalitetom. Cilj ovog rada bio je literaturni prikaz koncepta bezbednosti bolesnika i medicinskih grešaka, sa posebnim osvrtom na pregled definicija najznačajnijih termina u ovoj oblasti, analizu faktora koji determinišu nastanak medicinskih grešaka i razmatranje njihove klasifikacije. Tokom poslednje decenije je sa povećanjem svesti o problemu bezbednosti bolesnika povećan i broj istraživanja medicinskih grešaka. Tradicionalni pristup po kome su za redukciju incidenata i poboljšanje bezbednosti odgovorni zdravstveni radnici zamenjuje se savremenim konceptom, koji podrazumeva uključivanje svih aktera na svim sistemskim nivoima radi upravljanja rizicima prilikom pružanja zdravstvenih usluga. U razvijenim zemljama je započeta i primena prospektivnih modela upravljanja rizicima za određene procese u zdravstvenoj zaštiti. Međutim, sve ove studije se uglavnom sprovode na sekundarnom i tercijarnom nivou zdravstvene zaštite, dok ih na primarnom nivou gotovo uopšte nema. U Republici Srbiji je nedavno usvojen Pravilnik o pokazateljima kvaliteta zdravstvene zaštite, ali se uprkos implementaciji regulative, može uočiti trend značajnog nedostatka podataka u vezi sa bezbednošću bolesnika zbog neadekvatnog prijavljivanja od strane zdravstvenih ustanova. U budućnosti je neophodno nastaviti sa homogenizacijom terminologije, kao i povećati broj ispitivanja faktora koji doprinose nastanku medicinskih grešaka, a sa ciljem prospektivnog identifikovanja i prevencije rizika u sistemu zdravstvene zaštite, a posebno u zemljama u razvoju kao što je Republika Srbija.
PB  - Univerzitet u Nišu - Medicinski fakultet, Niš
T2  - Acta medica Medianae
T1  - Patient safety and medication errors in the provision of health care services-challenges for contemporary practice
T1  - Bezbednost bolesnika i medicinske greške u procesu pružanja zdravstvene zaštite - izazovi za savremenu praksu
VL  - 55
IS  - 2
SP  - 57
EP  - 64
DO  - 10.5633/amm.2016.0210
ER  - 
@article{
author = "Stojković, Tatjana and Marinković, Valentina and Krajnović, Dušanka and Tasić, Ljiljana and Milošević-Georgiev, Andrijana",
year = "2016",
abstract = "Non-maleficence represents one of the basic ethical principles that health care providers should be guided by during service delivery. Establishment of patient safety is nowadays recognized as an issue of global concern in health care and a critical component of quality management. The aim of this paper is to provide a literature review of the patient safety and medication errors concept, with special attention given to defining the most significant terms, analyzing the causal factors and reviewing their classification. Raising awareness about the importance of patient safety has resulted in an increase in the number of medication error studies over the last decade. The traditional approach which makes health workers responsible for reduction of incidents is replaced by the modern concept which implies the involvement of all stakeholders at all levels of the system. In developed countries, the application of prospective risk management models for specific health care processes has already started. However, all these studies are mainly carried out at the secondary and tertiary levels of health care, while they are almost non-existent at the primary level. In the Republic of Serbia, a Rulebook on indicators of the quality of health care has been recently adopted, but a trend of significant lack of data regarding patient safety can be noticed due to inadequate reporting. It is necessary to continue with the homogenization of terminology and to increase the number of analyses of causal factors with the aim of prospective risk identification, particularly in developing countries such as the Republic of Serbia., Neškodljivost predstavlja jedan od osnovnih etičkih principa kojim bi trebalo da se rukovode zdravstveni radnici prilikom pružanja usluga zdravstvene zaštite. Uspostavljanje i unapređenje bezbednosti bolesnika danas je prepoznato kao problem od globalnog značaja u zdravstvu i kritična komponenta upravljanja kvalitetom. Cilj ovog rada bio je literaturni prikaz koncepta bezbednosti bolesnika i medicinskih grešaka, sa posebnim osvrtom na pregled definicija najznačajnijih termina u ovoj oblasti, analizu faktora koji determinišu nastanak medicinskih grešaka i razmatranje njihove klasifikacije. Tokom poslednje decenije je sa povećanjem svesti o problemu bezbednosti bolesnika povećan i broj istraživanja medicinskih grešaka. Tradicionalni pristup po kome su za redukciju incidenata i poboljšanje bezbednosti odgovorni zdravstveni radnici zamenjuje se savremenim konceptom, koji podrazumeva uključivanje svih aktera na svim sistemskim nivoima radi upravljanja rizicima prilikom pružanja zdravstvenih usluga. U razvijenim zemljama je započeta i primena prospektivnih modela upravljanja rizicima za određene procese u zdravstvenoj zaštiti. Međutim, sve ove studije se uglavnom sprovode na sekundarnom i tercijarnom nivou zdravstvene zaštite, dok ih na primarnom nivou gotovo uopšte nema. U Republici Srbiji je nedavno usvojen Pravilnik o pokazateljima kvaliteta zdravstvene zaštite, ali se uprkos implementaciji regulative, može uočiti trend značajnog nedostatka podataka u vezi sa bezbednošću bolesnika zbog neadekvatnog prijavljivanja od strane zdravstvenih ustanova. U budućnosti je neophodno nastaviti sa homogenizacijom terminologije, kao i povećati broj ispitivanja faktora koji doprinose nastanku medicinskih grešaka, a sa ciljem prospektivnog identifikovanja i prevencije rizika u sistemu zdravstvene zaštite, a posebno u zemljama u razvoju kao što je Republika Srbija.",
publisher = "Univerzitet u Nišu - Medicinski fakultet, Niš",
journal = "Acta medica Medianae",
title = "Patient safety and medication errors in the provision of health care services-challenges for contemporary practice, Bezbednost bolesnika i medicinske greške u procesu pružanja zdravstvene zaštite - izazovi za savremenu praksu",
volume = "55",
number = "2",
pages = "57-64",
doi = "10.5633/amm.2016.0210"
}
Stojković, T., Marinković, V., Krajnović, D., Tasić, L.,& Milošević-Georgiev, A.. (2016). Patient safety and medication errors in the provision of health care services-challenges for contemporary practice. in Acta medica Medianae
Univerzitet u Nišu - Medicinski fakultet, Niš., 55(2), 57-64.
https://doi.org/10.5633/amm.2016.0210
Stojković T, Marinković V, Krajnović D, Tasić L, Milošević-Georgiev A. Patient safety and medication errors in the provision of health care services-challenges for contemporary practice. in Acta medica Medianae. 2016;55(2):57-64.
doi:10.5633/amm.2016.0210 .
Stojković, Tatjana, Marinković, Valentina, Krajnović, Dušanka, Tasić, Ljiljana, Milošević-Georgiev, Andrijana, "Patient safety and medication errors in the provision of health care services-challenges for contemporary practice" in Acta medica Medianae, 55, no. 2 (2016):57-64,
https://doi.org/10.5633/amm.2016.0210 . .
1

A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia

Marinković, Valentina; Bekcić, Stana; Đorđević, J.; Tasić, Ljiljana; Stojković, Tatjana

(Elsevier Science Inc, 2016)

TY  - CONF
AU  - Marinković, Valentina
AU  - Bekcić, Stana
AU  - Đorđević, J.
AU  - Tasić, Ljiljana
AU  - Stojković, Tatjana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2682
AB  - Objectives: To assess current attitudes of urologists to „off-label“ prescribing
of BCG vaccine for high grade non-muscle invasive bladder cancer (NMIBC) and
carcinoma-in-situ (CIS), as well as to perform a pharmacoeconomic evaluation
of BCG vaccine manufactured by local pharmaceutical company. Methods: The
attitudes and experiences of urologists regarding „off-label“ use of BCG vaccine
for intravesical immunotherapy of bladder cancer, have been evaluated by using
non-probability snowball sampling technique and specifically designed question-
naire. Clinical, social, economic, ethical and regulatory factors have been included.
Snowball sampling has involved urologists from ten different hospitals in the
Northern, Central and Southern Serbia, greatly experienced in intravesical BCG
immunotherapy. Results: BCG is used for intravesical immunotherapy, and has
become the standard care for NMIBC and CIS. BCG therapy may reduce the risk of
tumour progression, appearing to be better in preventing recurrences compared to
chemotherapy, but with significantly more side effects. „Off-label“ use is the use
of a medicinal product for another indication, another patient group, another dose
or by another route of administration as indicated in the package insert. It was
noted that BCG was in the „off-label” use in a 50,0% hospitals which had a problem
with purchase of BCG for immunotherapy (regarding worldwide shortages). It was
estimated that there were 1095 patients with bladder cancer in Serbia per year. The
model according to which 18 vials of domestic BCG vaccine are used for immu-
notherapy per patient per year, projected the net budget savings of 593 862.30 € per year. Conclusions: This research could support the further clinical studies
of BCG vaccine of local manufacturer, for new indications (NMIBC and CIS). That
would enable lower costs per patient, higher quality, availability and the continuous
supply of immunotherapy.
PB  - Elsevier Science Inc
C3  - Value in Health
T1  - A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia
VL  - 19
IS  - 7
SP  - A497
EP  - A498
DO  - 10.1016/j.jval.2016.09.875
ER  - 
@conference{
author = "Marinković, Valentina and Bekcić, Stana and Đorđević, J. and Tasić, Ljiljana and Stojković, Tatjana",
year = "2016",
abstract = "Objectives: To assess current attitudes of urologists to „off-label“ prescribing
of BCG vaccine for high grade non-muscle invasive bladder cancer (NMIBC) and
carcinoma-in-situ (CIS), as well as to perform a pharmacoeconomic evaluation
of BCG vaccine manufactured by local pharmaceutical company. Methods: The
attitudes and experiences of urologists regarding „off-label“ use of BCG vaccine
for intravesical immunotherapy of bladder cancer, have been evaluated by using
non-probability snowball sampling technique and specifically designed question-
naire. Clinical, social, economic, ethical and regulatory factors have been included.
Snowball sampling has involved urologists from ten different hospitals in the
Northern, Central and Southern Serbia, greatly experienced in intravesical BCG
immunotherapy. Results: BCG is used for intravesical immunotherapy, and has
become the standard care for NMIBC and CIS. BCG therapy may reduce the risk of
tumour progression, appearing to be better in preventing recurrences compared to
chemotherapy, but with significantly more side effects. „Off-label“ use is the use
of a medicinal product for another indication, another patient group, another dose
or by another route of administration as indicated in the package insert. It was
noted that BCG was in the „off-label” use in a 50,0% hospitals which had a problem
with purchase of BCG for immunotherapy (regarding worldwide shortages). It was
estimated that there were 1095 patients with bladder cancer in Serbia per year. The
model according to which 18 vials of domestic BCG vaccine are used for immu-
notherapy per patient per year, projected the net budget savings of 593 862.30 € per year. Conclusions: This research could support the further clinical studies
of BCG vaccine of local manufacturer, for new indications (NMIBC and CIS). That
would enable lower costs per patient, higher quality, availability and the continuous
supply of immunotherapy.",
publisher = "Elsevier Science Inc",
journal = "Value in Health",
title = "A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia",
volume = "19",
number = "7",
pages = "A497-A498",
doi = "10.1016/j.jval.2016.09.875"
}
Marinković, V., Bekcić, S., Đorđević, J., Tasić, L.,& Stojković, T.. (2016). A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia. in Value in Health
Elsevier Science Inc., 19(7), A497-A498.
https://doi.org/10.1016/j.jval.2016.09.875
Marinković V, Bekcić S, Đorđević J, Tasić L, Stojković T. A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia. in Value in Health. 2016;19(7):A497-A498.
doi:10.1016/j.jval.2016.09.875 .
Marinković, Valentina, Bekcić, Stana, Đorđević, J., Tasić, Ljiljana, Stojković, Tatjana, "A prospective assesment of attitudes and experiences among urologists regarding off label use of bcg vaccine in Serbia" in Value in Health, 19, no. 7 (2016):A497-A498,
https://doi.org/10.1016/j.jval.2016.09.875 . .

Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia

Stojković, Tatjana; Bogavac-Stanojević, Nataša; Marinković, Valentina; Lakić, Dragana

(Elsevier Science Inc, 2016)

TY  - CONF
AU  - Stojković, Tatjana
AU  - Bogavac-Stanojević, Nataša
AU  - Marinković, Valentina
AU  - Lakić, Dragana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2683
AB  - Objectives: A Pharmacist-Managed Warfarin Service (PMWS) is perceived as an
efficient method for improving anticoagulation control and decreasing the rate of
bleeding, thus reducing overall healthcare costs. What this study aims to assess is
a five-year budget impact of providing PMWS instead of Usual Medical Care (UMC)
to patients on warfarin at the secondary/tertiary level of healthcare facilities in
Serbia. Methods: A budget impact analysis was performed from the payer’s per-
spective (National Health Insurance Fund-NHIF), over a five-year time horizon. A
reference scenario (UMC) and a new one (PMWS) were defined for a cohort of 18,067
insured patients taking warfarin, with the pre-assumed annual population growth
rate of 20%, according to NHIF database. Direct medical costs included the acquisi-
tion costs of warfarin, blood products and drugs for anticoagulation reversal, as
well as hospitalization and monitoring. The expected values of annual therapy
were based on the probabilities of patient being well-controlled or hypercoagulated,
without any symptoms or with minor/major bleeding (pre-assumed incidence of
the adverse events was once in a year, during 10 days). Results: The projected net
cost savings have amounted to € 55,317, € 66,379, € 79,655, € 95,589 and € 114,704
for 2016, 2017, 2018, 2019 and 2020, respectively. Consequently, the total saving of €
411,644 could be achieved if PMWS was implemented, over a five-year period (2016-
2020), with a total budget reduction of 4.15%. The major economic benefits were
attributed to the decrease of hospitalization expenditures in case of PMWS, related
to the reduction of bleeding rates. ConClusions: Provision of PMWS instead of
UMC to patients on warfarin could result in substantial net budget savings, due to
improved both clinical and economic outcomes. Accordingly, this pharmaceutical
service has much to recommend it for the implementation in the healthcare system
of Serbia in the future.
PB  - Elsevier Science Inc
C3  - Value in Health
T1  - Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia
VL  - 19
IS  - 7
SP  - A626
DO  - 10.1016/j.jval.2016.09.1610
ER  - 
@conference{
author = "Stojković, Tatjana and Bogavac-Stanojević, Nataša and Marinković, Valentina and Lakić, Dragana",
year = "2016",
abstract = "Objectives: A Pharmacist-Managed Warfarin Service (PMWS) is perceived as an
efficient method for improving anticoagulation control and decreasing the rate of
bleeding, thus reducing overall healthcare costs. What this study aims to assess is
a five-year budget impact of providing PMWS instead of Usual Medical Care (UMC)
to patients on warfarin at the secondary/tertiary level of healthcare facilities in
Serbia. Methods: A budget impact analysis was performed from the payer’s per-
spective (National Health Insurance Fund-NHIF), over a five-year time horizon. A
reference scenario (UMC) and a new one (PMWS) were defined for a cohort of 18,067
insured patients taking warfarin, with the pre-assumed annual population growth
rate of 20%, according to NHIF database. Direct medical costs included the acquisi-
tion costs of warfarin, blood products and drugs for anticoagulation reversal, as
well as hospitalization and monitoring. The expected values of annual therapy
were based on the probabilities of patient being well-controlled or hypercoagulated,
without any symptoms or with minor/major bleeding (pre-assumed incidence of
the adverse events was once in a year, during 10 days). Results: The projected net
cost savings have amounted to € 55,317, € 66,379, € 79,655, € 95,589 and € 114,704
for 2016, 2017, 2018, 2019 and 2020, respectively. Consequently, the total saving of €
411,644 could be achieved if PMWS was implemented, over a five-year period (2016-
2020), with a total budget reduction of 4.15%. The major economic benefits were
attributed to the decrease of hospitalization expenditures in case of PMWS, related
to the reduction of bleeding rates. ConClusions: Provision of PMWS instead of
UMC to patients on warfarin could result in substantial net budget savings, due to
improved both clinical and economic outcomes. Accordingly, this pharmaceutical
service has much to recommend it for the implementation in the healthcare system
of Serbia in the future.",
publisher = "Elsevier Science Inc",
journal = "Value in Health",
title = "Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia",
volume = "19",
number = "7",
pages = "A626",
doi = "10.1016/j.jval.2016.09.1610"
}
Stojković, T., Bogavac-Stanojević, N., Marinković, V.,& Lakić, D.. (2016). Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia. in Value in Health
Elsevier Science Inc., 19(7), A626.
https://doi.org/10.1016/j.jval.2016.09.1610
Stojković T, Bogavac-Stanojević N, Marinković V, Lakić D. Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia. in Value in Health. 2016;19(7):A626.
doi:10.1016/j.jval.2016.09.1610 .
Stojković, Tatjana, Bogavac-Stanojević, Nataša, Marinković, Valentina, Lakić, Dragana, "Budget impact analysis of introducing pharmacist-managed warfarin service in the republic of Serbia" in Value in Health, 19, no. 7 (2016):A626,
https://doi.org/10.1016/j.jval.2016.09.1610 . .

Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine

Krajnović, Dušanka; Stojković, Tatjana; Babić, Sonja

(Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd, 2016)

TY  - JOUR
AU  - Krajnović, Dušanka
AU  - Stojković, Tatjana
AU  - Babić, Sonja
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2698
AB  - Objective: Stem cells could be defined as cell with an extraordinary capacity for self-renewal and the ability to differentiate into different cell types. The aim of this study is to examine students' opinion about the use of stem cells as health technologies in disease treatment and radical life extension. Method: Prospective cross-sectional study was conducted as a questionnaire, which was filled anonimly and voluntarily. Results: In this study 655 respondents have participated, with an average age 21.9±}1.8 years. High percentage distribution was concluded with most of the statements, with especially positive attitude towards the preservation of stem cells for their own treatment (84.2%), and treatment of their families (85.4%). Dominantly neutral attitude was expressed according to a statement about the reliability of stem cells and doubts about their implementation.(49.4%).There was no statistically significant difference in students' opinion between different faculties. Conclusion: It is important to evaluate students' opinion because it can obtain information on how the respondents agree with the potential implementation of health technology in the future and, accordingly, whether it is justified to continue further research. We should be more dedicated to informing students in the future, and this type of research should be implemented on a wider population to obtain the relevant results and perform more reliable conclusion.
AB  - Uvod: Matične ćelije funkcionalno se mogu definisati kao ćelije koje poseduju izvanredni kapacitet samoobnavljanja i sposobnost diferenciranja u različite tipove ćelija. One nisu samo karakarakteristične za embrionalni stadijum razvića individue, već su prisutne i u adultnim tkivima, gde predstavljaju bazu za obnavljanje ćelija tokom života. Zbog toga su kao nove zdravstvene tehnologije tesno povezane sa personalizovanim pristupom lečenju, kao i sa radikalnim produženjem života. Cilj rada: Ispitati stavove studenata u vezi sa upotrebom matičnih ćelija kao zdravstvenih tehnologija u lečenju bolesti i radikalnog produženja života. Metod rada: Sprovedena je prospektivna studija preseka sa namenski kreiranim upitnikom, koji su ispitanici popunjavali anonimno i dobrovoljno. Rezultati: U istraživanju je učestvovalo 655 ispitanika (studenata), prosečne starosti 21,9±}1,8 godina. Utvrđena je visoka procentualna zastupljenost slaganja sa većinom datih izjava i sa naročito pozitivnim stavom prema čuvanju matičnih ćelija za sopstveno lečenje (84,2%), odnosno lečenje svoje porodice (85,4%). Dominantno neutralan stav ispitanika je iskazan prema izjavi o pouzdanosti matičnih ćelija i sumnje u vezi sa njenom primenom (49,4%). Nije utvrđeno postojanje statistički značajne razlike stavova studenata različitih fakulteta ni sa jednom izjavom. Zaključak: Ispitivanje stavova studenata je značajno jer se dobijaju informacije o tome koliko su ispitanici saglasni sa potencijalnom implementacijom zdravstvene tehnologije u budućnosti i shodno tome da li je opravdano nastaviti dalja istraživanja. Rezultati ovog istraživanja su pokazali da su studenti uglavnom saglasni sa čuvanjem matičnih ćelija kako u cilju sopstvenog tako i lečenja članova svoje porodice, ali i da su, nasuprot tome, skeptični po pitanju pouzdanosti u primeni ovih metoda lečenja. U budućnosti bi trebalo posvetiti veću pažnju informisanju studenata i ovaj tip istraživanja je potrebno sprovesti na široj populaciji radi dobijanja što relevantnijih rezultata i izvođenja pouzdanijeg zaključka.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine
T1  - Etički aspekti upotrebe matičnih ćelija kao zdravstvenih tehnologija u personalizovanoj medicini
VL  - 38
IS  - 1
SP  - 5
EP  - 18
DO  - 10.5937/engrami1601005K
ER  - 
@article{
author = "Krajnović, Dušanka and Stojković, Tatjana and Babić, Sonja",
year = "2016",
abstract = "Objective: Stem cells could be defined as cell with an extraordinary capacity for self-renewal and the ability to differentiate into different cell types. The aim of this study is to examine students' opinion about the use of stem cells as health technologies in disease treatment and radical life extension. Method: Prospective cross-sectional study was conducted as a questionnaire, which was filled anonimly and voluntarily. Results: In this study 655 respondents have participated, with an average age 21.9±}1.8 years. High percentage distribution was concluded with most of the statements, with especially positive attitude towards the preservation of stem cells for their own treatment (84.2%), and treatment of their families (85.4%). Dominantly neutral attitude was expressed according to a statement about the reliability of stem cells and doubts about their implementation.(49.4%).There was no statistically significant difference in students' opinion between different faculties. Conclusion: It is important to evaluate students' opinion because it can obtain information on how the respondents agree with the potential implementation of health technology in the future and, accordingly, whether it is justified to continue further research. We should be more dedicated to informing students in the future, and this type of research should be implemented on a wider population to obtain the relevant results and perform more reliable conclusion., Uvod: Matične ćelije funkcionalno se mogu definisati kao ćelije koje poseduju izvanredni kapacitet samoobnavljanja i sposobnost diferenciranja u različite tipove ćelija. One nisu samo karakarakteristične za embrionalni stadijum razvića individue, već su prisutne i u adultnim tkivima, gde predstavljaju bazu za obnavljanje ćelija tokom života. Zbog toga su kao nove zdravstvene tehnologije tesno povezane sa personalizovanim pristupom lečenju, kao i sa radikalnim produženjem života. Cilj rada: Ispitati stavove studenata u vezi sa upotrebom matičnih ćelija kao zdravstvenih tehnologija u lečenju bolesti i radikalnog produženja života. Metod rada: Sprovedena je prospektivna studija preseka sa namenski kreiranim upitnikom, koji su ispitanici popunjavali anonimno i dobrovoljno. Rezultati: U istraživanju je učestvovalo 655 ispitanika (studenata), prosečne starosti 21,9±}1,8 godina. Utvrđena je visoka procentualna zastupljenost slaganja sa većinom datih izjava i sa naročito pozitivnim stavom prema čuvanju matičnih ćelija za sopstveno lečenje (84,2%), odnosno lečenje svoje porodice (85,4%). Dominantno neutralan stav ispitanika je iskazan prema izjavi o pouzdanosti matičnih ćelija i sumnje u vezi sa njenom primenom (49,4%). Nije utvrđeno postojanje statistički značajne razlike stavova studenata različitih fakulteta ni sa jednom izjavom. Zaključak: Ispitivanje stavova studenata je značajno jer se dobijaju informacije o tome koliko su ispitanici saglasni sa potencijalnom implementacijom zdravstvene tehnologije u budućnosti i shodno tome da li je opravdano nastaviti dalja istraživanja. Rezultati ovog istraživanja su pokazali da su studenti uglavnom saglasni sa čuvanjem matičnih ćelija kako u cilju sopstvenog tako i lečenja članova svoje porodice, ali i da su, nasuprot tome, skeptični po pitanju pouzdanosti u primeni ovih metoda lečenja. U budućnosti bi trebalo posvetiti veću pažnju informisanju studenata i ovaj tip istraživanja je potrebno sprovesti na široj populaciji radi dobijanja što relevantnijih rezultata i izvođenja pouzdanijeg zaključka.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine, Etički aspekti upotrebe matičnih ćelija kao zdravstvenih tehnologija u personalizovanoj medicini",
volume = "38",
number = "1",
pages = "5-18",
doi = "10.5937/engrami1601005K"
}
Krajnović, D., Stojković, T.,& Babić, S.. (2016). Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 38(1), 5-18.
https://doi.org/10.5937/engrami1601005K
Krajnović D, Stojković T, Babić S. Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine. in Engrami. 2016;38(1):5-18.
doi:10.5937/engrami1601005K .
Krajnović, Dušanka, Stojković, Tatjana, Babić, Sonja, "Ethical aspects of the stem cells' use as healthcare technologies in personalized medicine" in Engrami, 38, no. 1 (2016):5-18,
https://doi.org/10.5937/engrami1601005K . .

Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin

Stojković, Tatjana; Marinković, Valentina; Lakić, Dragana; Bogavac-Stanojević, Nataša

(Savez farmaceutskih udruženja Srbije, Beograd, 2016)

TY  - JOUR
AU  - Stojković, Tatjana
AU  - Marinković, Valentina
AU  - Lakić, Dragana
AU  - Bogavac-Stanojević, Nataša
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2747
AB  - It has been determined that Pharmacist-Managed Anticoagulation Service (PMAS) for patients on warfarin improves anticoagulation control and decreases the rate of bleeding, thus reducing the overall health care costs. This study aims to compare the cost-effectiveness of providing pharmaceutical care (PC) and usual medical care (UMC) to patients on warfarin, from the perspective of the National Health Insurance Fund (NHIF) in Serbia. The cost-effectiveness analysis was conducted, with a time horizon of 10 days. Decision tree modeling combined data on efficacy from eligible studies, while the costs were taken from NHIF Drug and Service fee lists. Additionally, the budget impact analysis was performed, aiming to project annual savings by implementing PMAS as a part of anticoagulation clinics. PC has been perceived to be cost-effective strategy, since it enables a higher probability of well controlled INR value (additional effectiveness 0,154), along with lower costs (-374,51 RSD), compared to UMC. Negative incremental cost-effectiveness ratio additionally demonstrated cost-effectiveness of PC, as dominant strategy. Sensitivity analysis confirmed the model robustness, and budget impact analysis has also demonstrated significant annual savings, in the total amount of 50.863.313 RSD for a five year period 2016-2020. Providing PC to patients on warfarin represents a more cost-efficient strategy than UMS, in addition to better safety profile, which is why it should be implemented in the national health care system in the future.
AB  - Utvrđeno je da sprovođenje menadžmenta terapije varfarinom od strane farmaceuta značajno unapređuje kontrolu antikoagulacije i smanjuje broj slučajeva krvarenja, a time i pridružene troškove lečenja. Cilj ovog rada je farmakoekonomska evaluacija pružanja farmaceutske zdravstvene zaštite (FZZ) pacijentima na varfarinu u odnosu na standardnu zdravstvenu zaštitu (SZZ), iz perspektive Republičkog fonda za zdravstveno osiguranje (RFZO). Sprovedena je analiza isplativosti primenom drveta odlučivanja, za period od 10 dana. U modelu su kombinovani podaci za posmatrane ishode iz odgovarajućih studija, dok su direktni medicinski troškovi preuzeti iz važećih cenovnika zdravstvenih usluga, kao i Liste lekova RFZO. Dodatno je sprovedena analiza uticaja na budžet, radi projektovanja potencijalnih ušteda u slučaju implementacije ove farmaceutske usluge. FZZ je troškovno isplativija strategija, obzirom na veću efektivnost (+0,154), a manji trošak (-374,51 RSD) u odnosu na SZZ. Negativna vrednost inkrementalnog odnosa troškova i efektivnosti za FZZ dodatno potvrđuje njenu isplativost, kao dominantne strategije. Analiza osetljivosti je potvrdila robusnost modela, dok su analizom uticaja na budžet projektovane značajne uštede, od 50.863.313 RSD za petogodišnji period 2016.-2020. Pružanje FZZ pacijentima na antikoagulantnoj terapiji varfarinom predstavlja troškovno-isplativiju strategiju u odnosu na SZZ u Republici Srbiji, zbog čega je poželjno da se implementira u nacionalni zdravstveni sistem u budućnosti.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin
T1  - Farmakoekonomska evaluacija pružanja farmaceutske usluge pacijentima na antikoagulantnoj terapiji varfarinom
VL  - 66
IS  - 2
SP  - 103
EP  - 117
DO  - 10.5937/arhfarm1602103S
ER  - 
@article{
author = "Stojković, Tatjana and Marinković, Valentina and Lakić, Dragana and Bogavac-Stanojević, Nataša",
year = "2016",
abstract = "It has been determined that Pharmacist-Managed Anticoagulation Service (PMAS) for patients on warfarin improves anticoagulation control and decreases the rate of bleeding, thus reducing the overall health care costs. This study aims to compare the cost-effectiveness of providing pharmaceutical care (PC) and usual medical care (UMC) to patients on warfarin, from the perspective of the National Health Insurance Fund (NHIF) in Serbia. The cost-effectiveness analysis was conducted, with a time horizon of 10 days. Decision tree modeling combined data on efficacy from eligible studies, while the costs were taken from NHIF Drug and Service fee lists. Additionally, the budget impact analysis was performed, aiming to project annual savings by implementing PMAS as a part of anticoagulation clinics. PC has been perceived to be cost-effective strategy, since it enables a higher probability of well controlled INR value (additional effectiveness 0,154), along with lower costs (-374,51 RSD), compared to UMC. Negative incremental cost-effectiveness ratio additionally demonstrated cost-effectiveness of PC, as dominant strategy. Sensitivity analysis confirmed the model robustness, and budget impact analysis has also demonstrated significant annual savings, in the total amount of 50.863.313 RSD for a five year period 2016-2020. Providing PC to patients on warfarin represents a more cost-efficient strategy than UMS, in addition to better safety profile, which is why it should be implemented in the national health care system in the future., Utvrđeno je da sprovođenje menadžmenta terapije varfarinom od strane farmaceuta značajno unapređuje kontrolu antikoagulacije i smanjuje broj slučajeva krvarenja, a time i pridružene troškove lečenja. Cilj ovog rada je farmakoekonomska evaluacija pružanja farmaceutske zdravstvene zaštite (FZZ) pacijentima na varfarinu u odnosu na standardnu zdravstvenu zaštitu (SZZ), iz perspektive Republičkog fonda za zdravstveno osiguranje (RFZO). Sprovedena je analiza isplativosti primenom drveta odlučivanja, za period od 10 dana. U modelu su kombinovani podaci za posmatrane ishode iz odgovarajućih studija, dok su direktni medicinski troškovi preuzeti iz važećih cenovnika zdravstvenih usluga, kao i Liste lekova RFZO. Dodatno je sprovedena analiza uticaja na budžet, radi projektovanja potencijalnih ušteda u slučaju implementacije ove farmaceutske usluge. FZZ je troškovno isplativija strategija, obzirom na veću efektivnost (+0,154), a manji trošak (-374,51 RSD) u odnosu na SZZ. Negativna vrednost inkrementalnog odnosa troškova i efektivnosti za FZZ dodatno potvrđuje njenu isplativost, kao dominantne strategije. Analiza osetljivosti je potvrdila robusnost modela, dok su analizom uticaja na budžet projektovane značajne uštede, od 50.863.313 RSD za petogodišnji period 2016.-2020. Pružanje FZZ pacijentima na antikoagulantnoj terapiji varfarinom predstavlja troškovno-isplativiju strategiju u odnosu na SZZ u Republici Srbiji, zbog čega je poželjno da se implementira u nacionalni zdravstveni sistem u budućnosti.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin, Farmakoekonomska evaluacija pružanja farmaceutske usluge pacijentima na antikoagulantnoj terapiji varfarinom",
volume = "66",
number = "2",
pages = "103-117",
doi = "10.5937/arhfarm1602103S"
}
Stojković, T., Marinković, V., Lakić, D.,& Bogavac-Stanojević, N.. (2016). Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 66(2), 103-117.
https://doi.org/10.5937/arhfarm1602103S
Stojković T, Marinković V, Lakić D, Bogavac-Stanojević N. Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin. in Arhiv za farmaciju. 2016;66(2):103-117.
doi:10.5937/arhfarm1602103S .
Stojković, Tatjana, Marinković, Valentina, Lakić, Dragana, Bogavac-Stanojević, Nataša, "Pharmacoeconomic evaluation of providing pharmacist-managed anticoagulation service to patients on warfarin" in Arhiv za farmaciju, 66, no. 2 (2016):103-117,
https://doi.org/10.5937/arhfarm1602103S . .
1

Research on presence of chosen risk factors for hypertension in medical students

Zeković, M.; Stojković, Tatjana; Milošević-Georgiev, Andrijana; Krajnović, Dušanka

(Univerzitet u Prištini - Medicinski fakultet, Kosovska Mitrovica, 2015)

TY  - JOUR
AU  - Zeković, M.
AU  - Stojković, Tatjana
AU  - Milošević-Georgiev, Andrijana
AU  - Krajnović, Dušanka
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2472
AB  - Hypertension represents one of the most significant preventable causes of death worldwide, and accordingly the target group for its prevention and early detection primarily refers to young population. Assessment of prevalence of selected risk factors for the development of hypertension among students, and determination of the existence of differences between genders, defined age groups and included faculties. A cross-sectional study was carried out during 2013., at Faculties of Medical Sciences, University of Belgrade. Respondents completed an questionnaire specially designed for the purpose of this study. Categorical data were analyzed using statistical chi-square test of independence. The study included 600 respondents, mainly female (61.2%), with the mean age of 53.1 ± 17.4 years. More than third of the participants (38,6%) reported the genetic predisposition to development of hypertension. Recorded modifiable risk factors were overweight (22,33%), regular extra salt intake (86,3%) and smoking (32,8%). The results of the study indicate presence of reversible risk factors in the observed population. Designing educational programs on chronic diseases during graduate studies is necessary to keep hypertension from developing at older age and mitigate the number of existing risk factors development.
AB  - Hipertenzija predstavlja jedan od najvažnijih preventabilnih uzroka smrtnosti širom sveta, na osnovu čega ciljnu grupu za njenu prevenciju i ranu detekciju čini pre svega populacija mladih. Ispitivanje zastupljenosti odabranih faktora rizika za razvoj hipertenzije u populaciji studenata, i postojanja razlike među polovima, definisanim starosnim grupama i fakultetima. Studija preseka sprovedena je tokom 2013. godine na fakultetima medicinskih nauka Univerziteta u Beogradu. Ispitanici su popunjavali namenski kreiran upitnik. Kategorički parametri su analizirani primenom statističkog Hi-kvadrat testa nezavisnosti. U studiji je učestvovalo 600 ispitanika prosečne starosti 23.96 ± 2.09 godina, od čega je bilo više osoba ženskog pola (61,2%). Genetsku predispoziciju za razvoj hipertenzije ima više od trećine ispitanika (38,6%). Od prisutnih preventabilnih faktora rizika kao najznačajniji su zabeleženi prekomerna uhranjenost (22.33%), redovan dodatni unos soli kroz konzumaciju slanih grickalica (86,3%) i pušenje (32,8%). Rezultati istraživanja ukazuju na zastupljenost reverzibilnih faktora rizika kod ispitivane populacije. Kako bi se sprečio razvoj hipertenzije u starijem životnom dobu i smanjio broj prisutnih faktora rizika neophodno je razvijanje edukativnih programa o hroničnim bolestima tokom perioda dodiplomskih studija.
PB  - Univerzitet u Prištini - Medicinski fakultet, Kosovska Mitrovica
T2  - Praxis medica
T1  - Research on presence of chosen risk factors for hypertension in medical students
T1  - Ispitivanje zastupljenosti odabranih faktora rizika za razvoj hipertenzije u populaciji studenata medicinskih fakulteta
VL  - 44
IS  - 2
SP  - 13
EP  - 19
DO  - 10.5937/pramed1502013Z
ER  - 
@article{
author = "Zeković, M. and Stojković, Tatjana and Milošević-Georgiev, Andrijana and Krajnović, Dušanka",
year = "2015",
abstract = "Hypertension represents one of the most significant preventable causes of death worldwide, and accordingly the target group for its prevention and early detection primarily refers to young population. Assessment of prevalence of selected risk factors for the development of hypertension among students, and determination of the existence of differences between genders, defined age groups and included faculties. A cross-sectional study was carried out during 2013., at Faculties of Medical Sciences, University of Belgrade. Respondents completed an questionnaire specially designed for the purpose of this study. Categorical data were analyzed using statistical chi-square test of independence. The study included 600 respondents, mainly female (61.2%), with the mean age of 53.1 ± 17.4 years. More than third of the participants (38,6%) reported the genetic predisposition to development of hypertension. Recorded modifiable risk factors were overweight (22,33%), regular extra salt intake (86,3%) and smoking (32,8%). The results of the study indicate presence of reversible risk factors in the observed population. Designing educational programs on chronic diseases during graduate studies is necessary to keep hypertension from developing at older age and mitigate the number of existing risk factors development., Hipertenzija predstavlja jedan od najvažnijih preventabilnih uzroka smrtnosti širom sveta, na osnovu čega ciljnu grupu za njenu prevenciju i ranu detekciju čini pre svega populacija mladih. Ispitivanje zastupljenosti odabranih faktora rizika za razvoj hipertenzije u populaciji studenata, i postojanja razlike među polovima, definisanim starosnim grupama i fakultetima. Studija preseka sprovedena je tokom 2013. godine na fakultetima medicinskih nauka Univerziteta u Beogradu. Ispitanici su popunjavali namenski kreiran upitnik. Kategorički parametri su analizirani primenom statističkog Hi-kvadrat testa nezavisnosti. U studiji je učestvovalo 600 ispitanika prosečne starosti 23.96 ± 2.09 godina, od čega je bilo više osoba ženskog pola (61,2%). Genetsku predispoziciju za razvoj hipertenzije ima više od trećine ispitanika (38,6%). Od prisutnih preventabilnih faktora rizika kao najznačajniji su zabeleženi prekomerna uhranjenost (22.33%), redovan dodatni unos soli kroz konzumaciju slanih grickalica (86,3%) i pušenje (32,8%). Rezultati istraživanja ukazuju na zastupljenost reverzibilnih faktora rizika kod ispitivane populacije. Kako bi se sprečio razvoj hipertenzije u starijem životnom dobu i smanjio broj prisutnih faktora rizika neophodno je razvijanje edukativnih programa o hroničnim bolestima tokom perioda dodiplomskih studija.",
publisher = "Univerzitet u Prištini - Medicinski fakultet, Kosovska Mitrovica",
journal = "Praxis medica",
title = "Research on presence of chosen risk factors for hypertension in medical students, Ispitivanje zastupljenosti odabranih faktora rizika za razvoj hipertenzije u populaciji studenata medicinskih fakulteta",
volume = "44",
number = "2",
pages = "13-19",
doi = "10.5937/pramed1502013Z"
}
Zeković, M., Stojković, T., Milošević-Georgiev, A.,& Krajnović, D.. (2015). Research on presence of chosen risk factors for hypertension in medical students. in Praxis medica
Univerzitet u Prištini - Medicinski fakultet, Kosovska Mitrovica., 44(2), 13-19.
https://doi.org/10.5937/pramed1502013Z
Zeković M, Stojković T, Milošević-Georgiev A, Krajnović D. Research on presence of chosen risk factors for hypertension in medical students. in Praxis medica. 2015;44(2):13-19.
doi:10.5937/pramed1502013Z .
Zeković, M., Stojković, Tatjana, Milošević-Georgiev, Andrijana, Krajnović, Dušanka, "Research on presence of chosen risk factors for hypertension in medical students" in Praxis medica, 44, no. 2 (2015):13-19,
https://doi.org/10.5937/pramed1502013Z . .
3