TY  - JOUR
AU  - Kundaković, Tatjana
AU  - Stanojković, Tatjana
AU  - Kolundžija, Branka
AU  - Marković, Stevan
AU  - Šukilović, Branka
AU  - Milenković, Marina
AU  - Lakušić, Branislava
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2217
AB  - The antimicrobial and cytotoxic activities of the essential oil of Satureja montana ssp. pisidica from two localities (mountains Korab and Galicica) were studied. Forty-nine components were identified in the each sample. Oxygenated monoterpene hydrocarbons were the major compounds: carvacrol, thymol, carvacrol methyl ether and beta-linalool. Both tested essential oils showed very high and similar antimicrobial activity. Minimal inhibitory concentrations ranged from 12.5 mu g/mL against S. epidermidis to 50 mu g/mL against P. aerugmosa and C. albicans. The cytotoxic effect of the essential oils was tested against MDA-MB-361, MDA-MB-453, HeLa, LS174 and MRCS cells. The essential oil from Korab demonstrated significantly better results than the oil from Galicica, particularly against HeLa and MDA-MB-453 cell lines, with IC50 values of 63.5 and 72.3 mu g/mL, while the oil from Galicica was the most active on the human epithelial cervical cancer HeLa cells (IC50 99.7 mu g/mL).
PB  - Sage Publications Inc, Thousand Oaks
T2  - Natural Product Communications
T1  - Cytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae)
VL  - 9
IS  - 4
SP  - 569
EP  - 572
UR  - https://hdl.handle.net/21.15107/rcub_farfar_2217
ER  - 

@article{
author = "Kundaković, Tatjana and Stanojković, Tatjana and Kolundžija, Branka and Marković, Stevan and Šukilović, Branka and Milenković, Marina and Lakušić, Branislava",
year = "2014",
abstract = "The antimicrobial and cytotoxic activities of the essential oil of Satureja montana ssp. pisidica from two localities (mountains Korab and Galicica) were studied. Forty-nine components were identified in the each sample. Oxygenated monoterpene hydrocarbons were the major compounds: carvacrol, thymol, carvacrol methyl ether and beta-linalool. Both tested essential oils showed very high and similar antimicrobial activity. Minimal inhibitory concentrations ranged from 12.5 mu g/mL against S. epidermidis to 50 mu g/mL against P. aerugmosa and C. albicans. The cytotoxic effect of the essential oils was tested against MDA-MB-361, MDA-MB-453, HeLa, LS174 and MRCS cells. The essential oil from Korab demonstrated significantly better results than the oil from Galicica, particularly against HeLa and MDA-MB-453 cell lines, with IC50 values of 63.5 and 72.3 mu g/mL, while the oil from Galicica was the most active on the human epithelial cervical cancer HeLa cells (IC50 99.7 mu g/mL).",
publisher = "Sage Publications Inc, Thousand Oaks",
journal = "Natural Product Communications",
title = "Cytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae)",
volume = "9",
number = "4",
pages = "569-572",
url = "https://hdl.handle.net/21.15107/rcub_farfar_2217"
}

Kundaković, T., Stanojković, T., Kolundžija, B., Marković, S., Šukilović, B., Milenković, M.,& Lakušić, B.. (2014). Cytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae). in Natural Product Communications
Sage Publications Inc, Thousand Oaks., 9(4), 569-572.
https://hdl.handle.net/21.15107/rcub_farfar_2217

Kundaković T, Stanojković T, Kolundžija B, Marković S, Šukilović B, Milenković M, Lakušić B. Cytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae). in Natural Product Communications. 2014;9(4):569-572.
https://hdl.handle.net/21.15107/rcub_farfar_2217 .

Kundaković, Tatjana, Stanojković, Tatjana, Kolundžija, Branka, Marković, Stevan, Šukilović, Branka, Milenković, Marina, Lakušić, Branislava, "Cytotoxicity and Antimicrobial Activity of the Essential Oil from Satureja montana subsp pisidica (Lamiceae)" in Natural Product Communications, 9, no. 4 (2014):569-572,
https://hdl.handle.net/21.15107/rcub_farfar_2217 .