TY  - JOUR
AU  - Popović, Kosana
AU  - Antonijević-Nikolić, Mirjana
AU  - Dražić, Branka
AU  - Jovanović, Dragoljub
AU  - Tanasković, Slađana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4295
AB  - Chemical components of teas have received great interest because they are related to health. In this work, data on the determination of foreign matter, loss on drying/water content, total ash and ash insoluble in hydrochloric acid are presented. The content of seven heavy metals including Cu, Fe, Mn, Zn, Ni, Cd and Pb were determined by atomic absorption spectrometry in samples of several herbal teas: Matricariae flos, Thymi herba, Menthae piperitae folium, Betulae folium, Quercus cortex, Gentianae radix, Frangulae cortex, Althaeae radix, Uvae ursi folium and Glycyrrhizae radix collected from Šabac’s market, Serbia. The sample preparation procedure involved dry digestion and dissolution of the ash in 6M HCl and then in 0.1 M HNO3. Herbal teas showed the concentration of heavy metals Cu, Fe, Mn, Zn and Ni in the range: 2.9 ± 0.1 – 22.2 ± 0.9 mg/kg, 118.5 ± 1.1 – 755.5 ± 2.5 mg/kg, 19.0 ± 5.8 – 561.0 ± 1.9 mg/kg, 6.5 ± 0.4 – 242.5 ± 1.4 mg/kg and 2.5 ± 0.1 – 10 ± 1.1 mg/kg, respectively. The level of copper in all samples was uniform. The highest content of Fe was in Thymi herba, while Mn and Zn were at maximum in Betulae folium. The levels of toxic heavy metals Cd and Pb were below the detection limit. The obtained values were compared with data available from literature. The herbal tea samples analyzed contained essential heavy metals (Cu, Fe, Mn, Zn) and probably essential in trace (Ni), and could obey the daily dietary requirements. Noncancer health risk assessment detected that the herbal teas of Betulae folium and Frangulae cortex can manifest some health risk to consumers.
PB  - Springer
T2  - Pharmaceutical Chemistry Journal
T1  - Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals
VL  - 56
IS  - 6
SP  - 827
EP  - 837
DO  - 10.1007/s11094-022-02716-w
ER  - 

@article{
author = "Popović, Kosana and Antonijević-Nikolić, Mirjana and Dražić, Branka and Jovanović, Dragoljub and Tanasković, Slađana",
year = "2022",
abstract = "Chemical components of teas have received great interest because they are related to health. In this work, data on the determination of foreign matter, loss on drying/water content, total ash and ash insoluble in hydrochloric acid are presented. The content of seven heavy metals including Cu, Fe, Mn, Zn, Ni, Cd and Pb were determined by atomic absorption spectrometry in samples of several herbal teas: Matricariae flos, Thymi herba, Menthae piperitae folium, Betulae folium, Quercus cortex, Gentianae radix, Frangulae cortex, Althaeae radix, Uvae ursi folium and Glycyrrhizae radix collected from Šabac’s market, Serbia. The sample preparation procedure involved dry digestion and dissolution of the ash in 6M HCl and then in 0.1 M HNO3. Herbal teas showed the concentration of heavy metals Cu, Fe, Mn, Zn and Ni in the range: 2.9 ± 0.1 – 22.2 ± 0.9 mg/kg, 118.5 ± 1.1 – 755.5 ± 2.5 mg/kg, 19.0 ± 5.8 – 561.0 ± 1.9 mg/kg, 6.5 ± 0.4 – 242.5 ± 1.4 mg/kg and 2.5 ± 0.1 – 10 ± 1.1 mg/kg, respectively. The level of copper in all samples was uniform. The highest content of Fe was in Thymi herba, while Mn and Zn were at maximum in Betulae folium. The levels of toxic heavy metals Cd and Pb were below the detection limit. The obtained values were compared with data available from literature. The herbal tea samples analyzed contained essential heavy metals (Cu, Fe, Mn, Zn) and probably essential in trace (Ni), and could obey the daily dietary requirements. Noncancer health risk assessment detected that the herbal teas of Betulae folium and Frangulae cortex can manifest some health risk to consumers.",
publisher = "Springer",
journal = "Pharmaceutical Chemistry Journal",
title = "Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals",
volume = "56",
number = "6",
pages = "827-837",
doi = "10.1007/s11094-022-02716-w"
}

Popović, K., Antonijević-Nikolić, M., Dražić, B., Jovanović, D.,& Tanasković, S.. (2022). Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals. in Pharmaceutical Chemistry Journal
Springer., 56(6), 827-837.
https://doi.org/10.1007/s11094-022-02716-w

Popović K, Antonijević-Nikolić M, Dražić B, Jovanović D, Tanasković S. Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals. in Pharmaceutical Chemistry Journal. 2022;56(6):827-837.
doi:10.1007/s11094-022-02716-w .

Popović, Kosana, Antonijević-Nikolić, Mirjana, Dražić, Branka, Jovanović, Dragoljub, Tanasković, Slađana, "Assessment of the Quality of Herbal Teas from Šabac, Serbia in Terms of the Content of Heavy Metals" in Pharmaceutical Chemistry Journal, 56, no. 6 (2022):827-837,
https://doi.org/10.1007/s11094-022-02716-w . .

TY  - JOUR
AU  - Dražić, Branka
AU  - Antonijević-Nikolić, Mirjana
AU  - Marinović-Cincović, Milena
AU  - Živković-Radovanović, Vukosava
AU  - Borović, Branka
AU  - Tanasković, Slađana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4205
AB  - Two new cationic Cu(II) complexes of cyclam (1,4,8,11-tetraaza- cyclotetradecane) and aminocarboxylate coligands glycine or alanine have been synthesized. The complexes were characterized by elemental analysis (C, H and N), molar electrical conductivity, magnetic susceptibility measurement at room temperature, spectral methods (UV/Vis and Fourier transform infrared), as well as by thermogravimetric (TG) and differential thermal analysis (DTA). The analytical data of the complexes show the formation of mononuclear com- plexes with general formula [Cu(L)cyc](ClO4 )2⋅nH2 O, A) L = glycine, n = 1.5 and B) L = alanine, n = 2.5. The tetradentate ligand cyclam was coordinated to metals through four N donors. The spectroscopic data suggested that the amino carboxylate ligands coordinated via their carboxylate ion moieties. The six- -coordinate octahedral geometry around Cu(II) in both complexes was pre- sumed. TG-DTA analysis indicated that complex B decomposed exothermally in a single step in the range of 310–400 °C. The cytotoxic activity of Cu(II) complexes and the starting ligands were tested against human cervix adenocar- cinoma cell line (HeLa), human melanoma (FemX) and human colon carci- noma (LS174). The IC50 values for the Cu(II) complexes were from 48.35– –82.25 μM. Both complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans.
AB  - Синтетисана су два нова катјонска Cu(II) комплекса са цикламом (1,4,8,11-тетра- азациклотетрадекан) и аминокарбоксилатним колигандима: глицином или аланином. Комплекси су окарактерисани елементалном анализом (C, H, N), моларном електрич- ном проводљивошћу, мерењем магнетног момента на собној температури, спектралним методама (UV/Vis и Fourier трансфомисаном инфрацрвеном спектроскопијом) као и термогравиметријском (TG) и диференцијалном термијском (DTA) анализом. Анали- тички подаци комплекса показују формирање мононуклеарних комплекса опште фор- муле [Cu(L)cyc](ClO4) 2∙nH2O, A) L = глицин, n = 1,5 и B) L = аланин, n = 2,5. Тетра- дентатни лиганд циклам је координован са металима преко четири N донора. Спектро- скопски подаци сугеришу да су аминокарбоксилатни лиганди координовани преко својих карбоксилатних јона. У оба комплекса претпостављена је октаедарска геометрија око Cu(II). TG-DTA анализа показује да се комплекс B егзотермно разлаже у једном кораку у опсегу од 310–400 °C. Цитотоксична активност Cu(II) комплекса и почетних лиганада је тестирана na ћелијским линијама хуманог аденокарцинома грлића мате- рице (HeLa), хуманог меланома (FemiX) и хуманог карцинома дебелог црева (LS174). Вредности IC50 за комплексe Cu(II) биле су од 48,35 до 82,25 μМ. Антимикробна активност oба комплекса je тестирана према Staphylococcus aureus, Bacillus subtilis, Esche- richia coli и Candida albicans.
PB  - Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies
T1  - Нови комплекси бакaр(ii)-циклама са аминокарбоксилатним
колигандима: синтеза, карактеризација и in vitro
антипролиферативна и антибактеријска анализа
VL  - 87
IS  - 4
SP  - 451
EP  - 464
DO  - 10.2298/JSC211107026D
ER  - 

@article{
author = "Dražić, Branka and Antonijević-Nikolić, Mirjana and Marinović-Cincović, Milena and Živković-Radovanović, Vukosava and Borović, Branka and Tanasković, Slađana",
year = "2022",
abstract = "Two new cationic Cu(II) complexes of cyclam (1,4,8,11-tetraaza- cyclotetradecane) and aminocarboxylate coligands glycine or alanine have been synthesized. The complexes were characterized by elemental analysis (C, H and N), molar electrical conductivity, magnetic susceptibility measurement at room temperature, spectral methods (UV/Vis and Fourier transform infrared), as well as by thermogravimetric (TG) and differential thermal analysis (DTA). The analytical data of the complexes show the formation of mononuclear com- plexes with general formula [Cu(L)cyc](ClO4 )2⋅nH2 O, A) L = glycine, n = 1.5 and B) L = alanine, n = 2.5. The tetradentate ligand cyclam was coordinated to metals through four N donors. The spectroscopic data suggested that the amino carboxylate ligands coordinated via their carboxylate ion moieties. The six- -coordinate octahedral geometry around Cu(II) in both complexes was pre- sumed. TG-DTA analysis indicated that complex B decomposed exothermally in a single step in the range of 310–400 °C. The cytotoxic activity of Cu(II) complexes and the starting ligands were tested against human cervix adenocar- cinoma cell line (HeLa), human melanoma (FemX) and human colon carci- noma (LS174). The IC50 values for the Cu(II) complexes were from 48.35– –82.25 μM. Both complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans., Синтетисана су два нова катјонска Cu(II) комплекса са цикламом (1,4,8,11-тетра- азациклотетрадекан) и аминокарбоксилатним колигандима: глицином или аланином. Комплекси су окарактерисани елементалном анализом (C, H, N), моларном електрич- ном проводљивошћу, мерењем магнетног момента на собној температури, спектралним методама (UV/Vis и Fourier трансфомисаном инфрацрвеном спектроскопијом) као и термогравиметријском (TG) и диференцијалном термијском (DTA) анализом. Анали- тички подаци комплекса показују формирање мононуклеарних комплекса опште фор- муле [Cu(L)cyc](ClO4) 2∙nH2O, A) L = глицин, n = 1,5 и B) L = аланин, n = 2,5. Тетра- дентатни лиганд циклам је координован са металима преко четири N донора. Спектро- скопски подаци сугеришу да су аминокарбоксилатни лиганди координовани преко својих карбоксилатних јона. У оба комплекса претпостављена је октаедарска геометрија око Cu(II). TG-DTA анализа показује да се комплекс B егзотермно разлаже у једном кораку у опсегу од 310–400 °C. Цитотоксична активност Cu(II) комплекса и почетних лиганада је тестирана na ћелијским линијама хуманог аденокарцинома грлића мате- рице (HeLa), хуманог меланома (FemiX) и хуманог карцинома дебелог црева (LS174). Вредности IC50 за комплексe Cu(II) биле су од 48,35 до 82,25 μМ. Антимикробна активност oба комплекса je тестирана према Staphylococcus aureus, Bacillus subtilis, Esche- richia coli и Candida albicans.",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies, Нови комплекси бакaр(ii)-циклама са аминокарбоксилатним
колигандима: синтеза, карактеризација и in vitro
антипролиферативна и антибактеријска анализа",
volume = "87",
number = "4",
pages = "451-464",
doi = "10.2298/JSC211107026D"
}

Dražić, B., Antonijević-Nikolić, M., Marinović-Cincović, M., Živković-Radovanović, V., Borović, B.,& Tanasković, S.. (2022). New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 87(4), 451-464.
https://doi.org/10.2298/JSC211107026D

Dražić B, Antonijević-Nikolić M, Marinović-Cincović M, Živković-Radovanović V, Borović B, Tanasković S. New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies. in Journal of the Serbian Chemical Society. 2022;87(4):451-464.
doi:10.2298/JSC211107026D .

Dražić, Branka, Antonijević-Nikolić, Mirjana, Marinović-Cincović, Milena, Živković-Radovanović, Vukosava, Borović, Branka, Tanasković, Slađana, "New copper(II) cyclam complexes with aminocarboxylate co-ligands: Synthesis, characterization, and in vitro antiproliferative and antibacterial studies" in Journal of the Serbian Chemical Society, 87, no. 4 (2022):451-464,
https://doi.org/10.2298/JSC211107026D . .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Antonijević-Nikolić, Mirjana
AU  - Dražić, Branka
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4051
AB  - A large number of interesting Co (II) complexes with macrocyclicligands have been synthesized and the recognition of its complexes as important bioactive compounds in vitro and in vivo has aroused growing interest in these agents as potential drugs for therapeutic use in various diseases. Numerous available information on their bioinorganic properties and mode of action in several biological systems, combined with the new possibilities imposed by the development of medical chemistry, opens space for the development of a new generation of highly active drugs with minimized side effects which could add significantly to the current clinical research and practice. In this paper we attempt to present some properties of the earlier isolated the first Co(II)tpmc complex for which crystal structure confirmed chair conformation of macrocycle. Complex with formula [Co2(Cl)2tpmc](BF4)2 (tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane), was studied on thermal behaviour and biological activity. TG-DTA analysis indicates that complex decomposition in a single step in the range of 365-435 °C. Investigated cytotoxic activity against two human cancer cell lines: HeLa (human cervix adenocarcinoma) and K562 (human myelogenous leukaemia). Complex was also preliminary assayed in vitro toward bacteria, fungi and mould together with the starting material for the synthesis (ligands, simple salts and solvents) as test substances. Investigated complex showed a moderate activity against strains of bacteria and were inactive against the tested fungi and mould. Minimal inhibitory concentration suppressing the visible growth of bacteria was determined. Biological investigations show the complex has significant cytotoxic potential.
AB  - Poznavanje biološke uloge kobalta i prepoznavanje njegovih kompleksa kao važnih bioaktivnih jedinjenja razlozi su sve veće zainteresovanosti za potencijalnu terapijsku primenu ovih kompleksa kod različitih bolesti. Brojne dostupne informacije o njihovim osobinama i načinu delovanja u nekoliko bioloških sistema, u kombinaciji sa novim mogućnostima koje nameće razvoj medicinske hemije, otvaraju prostor za razvoj nove generacije visoko aktivnih lekova sa minimalnim nuspojavama. U ovom radu smo ispitali neke osobine ranije izolovanog Co (II) tpmc kompleksa, prvog kod koga je rendgenska strukturna analiza potvrdila da se makrciklični ligand nalazi u konformaciji stolice. Ispitivane su termogravimetrijske I biološke osobine kompleksa [Co2(Cl)2tpmc](BF4)2 (tpmc = N, N', N'', N'''-tetrakis (2-piridilmetil) -1,4,8,11-tetraazaciklotetradekan). TG-DTA analiza ukazuje da je razlaganje kompleksa u jednom koraku u rasponu temperature od 365 -435 ° C. Ispitivana je citotoksična aktivnost na dve ljudske ćelijske linije karcinoma: HeLa (adenokarcinom grlića maternice) i K562 (mijelogena leukemija). Antimikrobno djelovanje kompleksa kvantifikovano je određivanjem minimalne inhibitorne koncentracije (MIC) korišćenjem bakterija Staphylococcus saprophyticus, Staphylococcus xylosus, Bacillus cereus, soja kvasca Candida albicans i plesni Aspergillus niger. Biološka ispitivanja su pokazala da kompleks ima značajan citotoksični potencijal I umerenu aktivnost prema bakterijama soja Staphylococcus.
PB  - Engineers Society for Corrosion
T2  - Materials Protection
T1  - Thermal behavior and biological activity of [Co2(Cl)2 tpmc](BF4)2 complex
T1  - Termičko ponašanje i biološka aktivnost [co2(cl)2 tpmc](bf4)2 kompleksa
VL  - 62
IS  - 4
SP  - 291
EP  - 296
DO  - 10.5937/zasmat2104291T
ER  - 

@article{
author = "Tanasković, Slađana and Antonijević-Nikolić, Mirjana and Dražić, Branka",
year = "2021",
abstract = "A large number of interesting Co (II) complexes with macrocyclicligands have been synthesized and the recognition of its complexes as important bioactive compounds in vitro and in vivo has aroused growing interest in these agents as potential drugs for therapeutic use in various diseases. Numerous available information on their bioinorganic properties and mode of action in several biological systems, combined with the new possibilities imposed by the development of medical chemistry, opens space for the development of a new generation of highly active drugs with minimized side effects which could add significantly to the current clinical research and practice. In this paper we attempt to present some properties of the earlier isolated the first Co(II)tpmc complex for which crystal structure confirmed chair conformation of macrocycle. Complex with formula [Co2(Cl)2tpmc](BF4)2 (tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane), was studied on thermal behaviour and biological activity. TG-DTA analysis indicates that complex decomposition in a single step in the range of 365-435 °C. Investigated cytotoxic activity against two human cancer cell lines: HeLa (human cervix adenocarcinoma) and K562 (human myelogenous leukaemia). Complex was also preliminary assayed in vitro toward bacteria, fungi and mould together with the starting material for the synthesis (ligands, simple salts and solvents) as test substances. Investigated complex showed a moderate activity against strains of bacteria and were inactive against the tested fungi and mould. Minimal inhibitory concentration suppressing the visible growth of bacteria was determined. Biological investigations show the complex has significant cytotoxic potential., Poznavanje biološke uloge kobalta i prepoznavanje njegovih kompleksa kao važnih bioaktivnih jedinjenja razlozi su sve veće zainteresovanosti za potencijalnu terapijsku primenu ovih kompleksa kod različitih bolesti. Brojne dostupne informacije o njihovim osobinama i načinu delovanja u nekoliko bioloških sistema, u kombinaciji sa novim mogućnostima koje nameće razvoj medicinske hemije, otvaraju prostor za razvoj nove generacije visoko aktivnih lekova sa minimalnim nuspojavama. U ovom radu smo ispitali neke osobine ranije izolovanog Co (II) tpmc kompleksa, prvog kod koga je rendgenska strukturna analiza potvrdila da se makrciklični ligand nalazi u konformaciji stolice. Ispitivane su termogravimetrijske I biološke osobine kompleksa [Co2(Cl)2tpmc](BF4)2 (tpmc = N, N', N'', N'''-tetrakis (2-piridilmetil) -1,4,8,11-tetraazaciklotetradekan). TG-DTA analiza ukazuje da je razlaganje kompleksa u jednom koraku u rasponu temperature od 365 -435 ° C. Ispitivana je citotoksična aktivnost na dve ljudske ćelijske linije karcinoma: HeLa (adenokarcinom grlića maternice) i K562 (mijelogena leukemija). Antimikrobno djelovanje kompleksa kvantifikovano je određivanjem minimalne inhibitorne koncentracije (MIC) korišćenjem bakterija Staphylococcus saprophyticus, Staphylococcus xylosus, Bacillus cereus, soja kvasca Candida albicans i plesni Aspergillus niger. Biološka ispitivanja su pokazala da kompleks ima značajan citotoksični potencijal I umerenu aktivnost prema bakterijama soja Staphylococcus.",
publisher = "Engineers Society for Corrosion",
journal = "Materials Protection",
title = "Thermal behavior and biological activity of [Co2(Cl)2 tpmc](BF4)2 complex, Termičko ponašanje i biološka aktivnost [co2(cl)2 tpmc](bf4)2 kompleksa",
volume = "62",
number = "4",
pages = "291-296",
doi = "10.5937/zasmat2104291T"
}

Tanasković, S., Antonijević-Nikolić, M.,& Dražić, B.. (2021). Thermal behavior and biological activity of [Co2(Cl)2 tpmc](BF4)2 complex. in Materials Protection
Engineers Society for Corrosion., 62(4), 291-296.
https://doi.org/10.5937/zasmat2104291T

Tanasković S, Antonijević-Nikolić M, Dražić B. Thermal behavior and biological activity of [Co2(Cl)2 tpmc](BF4)2 complex. in Materials Protection. 2021;62(4):291-296.
doi:10.5937/zasmat2104291T .

Tanasković, Slađana, Antonijević-Nikolić, Mirjana, Dražić, Branka, "Thermal behavior and biological activity of [Co2(Cl)2 tpmc](BF4)2 complex" in Materials Protection, 62, no. 4 (2021):291-296,
https://doi.org/10.5937/zasmat2104291T . .

TY  - JOUR
AU  - Dražić, Branka
AU  - Antonijević-Nikolić, Mirjana
AU  - Žižak, Željko
AU  - Tanasković, Slađana
PY  - 2020
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3650
AB  - Two   new   complexes   with   the   general   formula [Cu2(L)tpmc](ClO4)3·nH2O  (tpmc  = N,N′,N′′,N′′′-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane,  L  = N-methylglycine, n =  3;  L  = N,N- -dimethylglycine, n = 2) were isolated and their composition, some physical and  chemical  properties  and  geometries  were  proposed  based  on  elemental analysis (C, H, N), conductometric and magnetic measurements and spectro-scopic data (UV–Vis, FTIR). It is evident that the complexes are binuclear and an exo coordination mode of the macrocyclic ligand in the boat conformation was proposed. The co-ligands are coordinated as a bridge using both oxygen atoms of the OCO- group. The cytotoxic activity of Cu(II) complexes as well as  their  Co(II)  analogs,  the  starting  ligands  and  the  free  salts  were  tested against human cervix adenocarcinoma cell line (HeLa), human chronic myelo-genous leukemia cells (K562), human breast cancer cell line (MDA-MB-453), and a non-cancerous cell line, human embryonic lung fibroblast (MRC-5). The IC50 values for the Cu(II) complexes were from 21.6±0.04 to 66.1±0.8, and for the Co(II) analogs were within the range from 8.8±0.74 to 15.40±1.52. All four complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans.
PB  - Belgrade : Serbian Chemical Society
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous
VL  - 85
IS  - 5
SP  - 637
EP  - 649
DO  - 10.2298/JSC190710088D
ER  - 

@article{
author = "Dražić, Branka and Antonijević-Nikolić, Mirjana and Žižak, Željko and Tanasković, Slađana",
year = "2020",
abstract = "Two   new   complexes   with   the   general   formula [Cu2(L)tpmc](ClO4)3·nH2O  (tpmc  = N,N′,N′′,N′′′-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane,  L  = N-methylglycine, n =  3;  L  = N,N- -dimethylglycine, n = 2) were isolated and their composition, some physical and  chemical  properties  and  geometries  were  proposed  based  on  elemental analysis (C, H, N), conductometric and magnetic measurements and spectro-scopic data (UV–Vis, FTIR). It is evident that the complexes are binuclear and an exo coordination mode of the macrocyclic ligand in the boat conformation was proposed. The co-ligands are coordinated as a bridge using both oxygen atoms of the OCO- group. The cytotoxic activity of Cu(II) complexes as well as  their  Co(II)  analogs,  the  starting  ligands  and  the  free  salts  were  tested against human cervix adenocarcinoma cell line (HeLa), human chronic myelo-genous leukemia cells (K562), human breast cancer cell line (MDA-MB-453), and a non-cancerous cell line, human embryonic lung fibroblast (MRC-5). The IC50 values for the Cu(II) complexes were from 21.6±0.04 to 66.1±0.8, and for the Co(II) analogs were within the range from 8.8±0.74 to 15.40±1.52. All four complexes were tested for their antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and the yeast Candida albicans.",
publisher = "Belgrade : Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous",
volume = "85",
number = "5",
pages = "637-649",
doi = "10.2298/JSC190710088D"
}

Dražić, B., Antonijević-Nikolić, M., Žižak, Ž.,& Tanasković, S.. (2020). Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous. in Journal of the Serbian Chemical Society
Belgrade : Serbian Chemical Society., 85(5), 637-649.
https://doi.org/10.2298/JSC190710088D

Dražić B, Antonijević-Nikolić M, Žižak Ž, Tanasković S. Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous. in Journal of the Serbian Chemical Society. 2020;85(5):637-649.
doi:10.2298/JSC190710088D .

Dražić, Branka, Antonijević-Nikolić, Mirjana, Žižak, Željko, Tanasković, Slađana, "Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous" in Journal of the Serbian Chemical Society, 85, no. 5 (2020):637-649,
https://doi.org/10.2298/JSC190710088D . .

TY  - JOUR
AU  - Antonijević-Nikolić, Mirjana
AU  - Antić-Stanković, Jelena
AU  - Dražić, Branka
AU  - Tanasković, Slađana
PY  - 2019
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3336
AB  - New cationic mixed-ligand tetranuclear complex [Cu-4(tpht) (tpmc)(2)](ClO4)(6)center dot 5H(2)O (tpmc = N, N', N '', N"'-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane, H(2)tpht - terephthalic acid (benzene-1,4-dicarboxylic acid)) was prepared and characterized by elemental analysis (C, H, N, Cu), UV/Vis, IR, EPR (X-band) spectra, conductivity, cyclic voltammetry and magnetic measurements (SQUID). Five coordinated geometry for new Cu(II) complex is proposed. The central metal ion is coordinated with two pyridyl and two cyclam nitrogens and bridged with -N-(CH2)(3)-N- fragments of the cyclam ring and OCO- of the terephthalate anion. Copper (II) ions are coordinated out of cyclam rings and one OCO- group from tpht bridges two Cu(II) inside tpmc unit and two Cu(2)tpmc units are bridged by dicarboxylate tpht dianion engaging all four oxygen atoms. Weak ferromagnetic interaction between copper (II) ions in new tetranuclear complex is observed, Weiss constant theta = 0.21 K and C = 0.398 cm(3) Kmol(-1). The new complex, related Cu(II) complexes with bridged benzene carboxylate, [Cu-2(C6H5COO)tpmc](ClO4)(3)center dot CH3OH, [Cu-2(Hpht)tpmc](ClO4)(3)center dot 3H(2)O (H(2)pht = phthalic acid), [Cu-4(ipht) (tpmc)(2)](ClO4)(6)center dot NaClO4 center dot 2CH(3)CN (H(2)ipht = isophthalic acid), solvents, starting salts and ligands were in vitro evaluated for antiproliferative and antibacterial activity. Antiproliferative evaluation was carried out using tumour cell lines: HeLa (human adenocarcinoma) and K562 (chronic myelogenous leukaemia). Among all tested compounds, the ipht complex revealed the highest antiproliferative activity. According to antibacterial screening results, most active compound was the benzoate complex against Micrococcus lysodeikticus.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Molecular Structure
T1  - New macrocyclic Cu(II) complex with bridge terephthalate: Synthesis, spectral properties, in vitro cytotoxic and antimicrobial activity. Comparison with related complexes
VL  - 1184
SP  - 41
EP  - 48
DO  - 10.1016/j.molstruc.2018.10.027
ER  - 

@article{
author = "Antonijević-Nikolić, Mirjana and Antić-Stanković, Jelena and Dražić, Branka and Tanasković, Slađana",
year = "2019",
abstract = "New cationic mixed-ligand tetranuclear complex [Cu-4(tpht) (tpmc)(2)](ClO4)(6)center dot 5H(2)O (tpmc = N, N', N '', N"'-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane, H(2)tpht - terephthalic acid (benzene-1,4-dicarboxylic acid)) was prepared and characterized by elemental analysis (C, H, N, Cu), UV/Vis, IR, EPR (X-band) spectra, conductivity, cyclic voltammetry and magnetic measurements (SQUID). Five coordinated geometry for new Cu(II) complex is proposed. The central metal ion is coordinated with two pyridyl and two cyclam nitrogens and bridged with -N-(CH2)(3)-N- fragments of the cyclam ring and OCO- of the terephthalate anion. Copper (II) ions are coordinated out of cyclam rings and one OCO- group from tpht bridges two Cu(II) inside tpmc unit and two Cu(2)tpmc units are bridged by dicarboxylate tpht dianion engaging all four oxygen atoms. Weak ferromagnetic interaction between copper (II) ions in new tetranuclear complex is observed, Weiss constant theta = 0.21 K and C = 0.398 cm(3) Kmol(-1). The new complex, related Cu(II) complexes with bridged benzene carboxylate, [Cu-2(C6H5COO)tpmc](ClO4)(3)center dot CH3OH, [Cu-2(Hpht)tpmc](ClO4)(3)center dot 3H(2)O (H(2)pht = phthalic acid), [Cu-4(ipht) (tpmc)(2)](ClO4)(6)center dot NaClO4 center dot 2CH(3)CN (H(2)ipht = isophthalic acid), solvents, starting salts and ligands were in vitro evaluated for antiproliferative and antibacterial activity. Antiproliferative evaluation was carried out using tumour cell lines: HeLa (human adenocarcinoma) and K562 (chronic myelogenous leukaemia). Among all tested compounds, the ipht complex revealed the highest antiproliferative activity. According to antibacterial screening results, most active compound was the benzoate complex against Micrococcus lysodeikticus.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Molecular Structure",
title = "New macrocyclic Cu(II) complex with bridge terephthalate: Synthesis, spectral properties, in vitro cytotoxic and antimicrobial activity. Comparison with related complexes",
volume = "1184",
pages = "41-48",
doi = "10.1016/j.molstruc.2018.10.027"
}

Antonijević-Nikolić, M., Antić-Stanković, J., Dražić, B.,& Tanasković, S.. (2019). New macrocyclic Cu(II) complex with bridge terephthalate: Synthesis, spectral properties, in vitro cytotoxic and antimicrobial activity. Comparison with related complexes. in Journal of Molecular Structure
Elsevier Science BV, Amsterdam., 1184, 41-48.
https://doi.org/10.1016/j.molstruc.2018.10.027

Antonijević-Nikolić M, Antić-Stanković J, Dražić B, Tanasković S. New macrocyclic Cu(II) complex with bridge terephthalate: Synthesis, spectral properties, in vitro cytotoxic and antimicrobial activity. Comparison with related complexes. in Journal of Molecular Structure. 2019;1184:41-48.
doi:10.1016/j.molstruc.2018.10.027 .

Antonijević-Nikolić, Mirjana, Antić-Stanković, Jelena, Dražić, Branka, Tanasković, Slađana, "New macrocyclic Cu(II) complex with bridge terephthalate: Synthesis, spectral properties, in vitro cytotoxic and antimicrobial activity. Comparison with related complexes" in Journal of Molecular Structure, 1184 (2019):41-48,
https://doi.org/10.1016/j.molstruc.2018.10.027 . .

TY  - JOUR
AU  - Antonijević-Nikolić, Mirjana
AU  - Antić-Stanković, Jelena
AU  - Tanasković, Slađana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3083
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3426
AB  - AbstrcatNew cationic tetranuclear Co(II) and neutral binuclear Cu(II) complexes with tpmc (N,N,N,N-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane) and bridging pyromellitate ligand pma (tetraanion 1,2,4,5-benzenetetracarboxylic acid) were isolated. The composition of the compounds is proposed based on elemental analyses (C, H, N, M=Cu, Co), molar conductivity determination, UV-Vis, FTIR, EPR, LC-MS and reflectance spectroscopy, magnetic measurements, cyclic voltammetry, as well as TG and DTA. It is proposed that in [Co-4(pma)(tpmc)(2)](ClO4)(4)6H(2)O (1), cobalt(II) is six-coordinate out of cyclam rings and one OCO- from pma participates in coordination with one Co(II). In the case of [Cu-2(pma)tpmc].8H(2)O (2), one OCO- from pma bridges two Cu(II). The cytotoxic activity of 1 and 2 was tested against tumor cell lines human cervix adenocarcinoma (HeLa), estrogen-receptor-positive human breast cancer (MCF-7), human myelogenous leukemia (K562), and the human Caucasian Burkitt's lymphoma (Ramos). The IC50 values for 1 and 2 were within the range 44.66 +/- 2.39 to 152.40 +/- 2.28M, and from 140.88 +/- 3.51 to 192.05 +/- 2.09M, respectively. Both 1 and 2 were tested for antimicrobial activity. We determined that minimal inhibitory concentration for 1 against Staphylococcus aureus, Bacillus subtilis, and Klebsiella pneumoniae was 25mM. Complex 2 did not express activity against tested microbial strains.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Coordination Chemistry
T1  - Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid
VL  - 71
IS  - 10
SP  - 1542
EP  - 1559
DO  - 10.1080/00958972.2018.1459581
ER  - 

@article{
author = "Antonijević-Nikolić, Mirjana and Antić-Stanković, Jelena and Tanasković, Slađana",
year = "2018",
abstract = "AbstrcatNew cationic tetranuclear Co(II) and neutral binuclear Cu(II) complexes with tpmc (N,N,N,N-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane) and bridging pyromellitate ligand pma (tetraanion 1,2,4,5-benzenetetracarboxylic acid) were isolated. The composition of the compounds is proposed based on elemental analyses (C, H, N, M=Cu, Co), molar conductivity determination, UV-Vis, FTIR, EPR, LC-MS and reflectance spectroscopy, magnetic measurements, cyclic voltammetry, as well as TG and DTA. It is proposed that in [Co-4(pma)(tpmc)(2)](ClO4)(4)6H(2)O (1), cobalt(II) is six-coordinate out of cyclam rings and one OCO- from pma participates in coordination with one Co(II). In the case of [Cu-2(pma)tpmc].8H(2)O (2), one OCO- from pma bridges two Cu(II). The cytotoxic activity of 1 and 2 was tested against tumor cell lines human cervix adenocarcinoma (HeLa), estrogen-receptor-positive human breast cancer (MCF-7), human myelogenous leukemia (K562), and the human Caucasian Burkitt's lymphoma (Ramos). The IC50 values for 1 and 2 were within the range 44.66 +/- 2.39 to 152.40 +/- 2.28M, and from 140.88 +/- 3.51 to 192.05 +/- 2.09M, respectively. Both 1 and 2 were tested for antimicrobial activity. We determined that minimal inhibitory concentration for 1 against Staphylococcus aureus, Bacillus subtilis, and Klebsiella pneumoniae was 25mM. Complex 2 did not express activity against tested microbial strains.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Coordination Chemistry",
title = "Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid",
volume = "71",
number = "10",
pages = "1542-1559",
doi = "10.1080/00958972.2018.1459581"
}

Antonijević-Nikolić, M., Antić-Stanković, J.,& Tanasković, S.. (2018). Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid. in Journal of Coordination Chemistry
Taylor & Francis Ltd, Abingdon., 71(10), 1542-1559.
https://doi.org/10.1080/00958972.2018.1459581

Antonijević-Nikolić M, Antić-Stanković J, Tanasković S. Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid. in Journal of Coordination Chemistry. 2018;71(10):1542-1559.
doi:10.1080/00958972.2018.1459581 .

Antonijević-Nikolić, Mirjana, Antić-Stanković, Jelena, Tanasković, Slađana, "Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid" in Journal of Coordination Chemistry, 71, no. 10 (2018):1542-1559,
https://doi.org/10.1080/00958972.2018.1459581 . .

TY  - JOUR
AU  - Antonijević-Nikolić, Mirjana
AU  - Antić-Stanković, Jelena
AU  - Tanasković, Slađana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3083
AB  - AbstrcatNew cationic tetranuclear Co(II) and neutral binuclear Cu(II) complexes with tpmc (N,N,N,N-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane) and bridging pyromellitate ligand pma (tetraanion 1,2,4,5-benzenetetracarboxylic acid) were isolated. The composition of the compounds is proposed based on elemental analyses (C, H, N, M=Cu, Co), molar conductivity determination, UV-Vis, FTIR, EPR, LC-MS and reflectance spectroscopy, magnetic measurements, cyclic voltammetry, as well as TG and DTA. It is proposed that in [Co-4(pma)(tpmc)(2)](ClO4)(4)6H(2)O (1), cobalt(II) is six-coordinate out of cyclam rings and one OCO- from pma participates in coordination with one Co(II). In the case of [Cu-2(pma)tpmc].8H(2)O (2), one OCO- from pma bridges two Cu(II). The cytotoxic activity of 1 and 2 was tested against tumor cell lines human cervix adenocarcinoma (HeLa), estrogen-receptor-positive human breast cancer (MCF-7), human myelogenous leukemia (K562), and the human Caucasian Burkitt's lymphoma (Ramos). The IC50 values for 1 and 2 were within the range 44.66 +/- 2.39 to 152.40 +/- 2.28M, and from 140.88 +/- 3.51 to 192.05 +/- 2.09M, respectively. Both 1 and 2 were tested for antimicrobial activity. We determined that minimal inhibitory concentration for 1 against Staphylococcus aureus, Bacillus subtilis, and Klebsiella pneumoniae was 25mM. Complex 2 did not express activity against tested microbial strains.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Coordination Chemistry
T1  - Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid
VL  - 71
IS  - 10
SP  - 1542
EP  - 1559
DO  - 10.1080/00958972.2018.1459581
ER  - 

@article{
author = "Antonijević-Nikolić, Mirjana and Antić-Stanković, Jelena and Tanasković, Slađana",
year = "2018",
abstract = "AbstrcatNew cationic tetranuclear Co(II) and neutral binuclear Cu(II) complexes with tpmc (N,N,N,N-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane) and bridging pyromellitate ligand pma (tetraanion 1,2,4,5-benzenetetracarboxylic acid) were isolated. The composition of the compounds is proposed based on elemental analyses (C, H, N, M=Cu, Co), molar conductivity determination, UV-Vis, FTIR, EPR, LC-MS and reflectance spectroscopy, magnetic measurements, cyclic voltammetry, as well as TG and DTA. It is proposed that in [Co-4(pma)(tpmc)(2)](ClO4)(4)6H(2)O (1), cobalt(II) is six-coordinate out of cyclam rings and one OCO- from pma participates in coordination with one Co(II). In the case of [Cu-2(pma)tpmc].8H(2)O (2), one OCO- from pma bridges two Cu(II). The cytotoxic activity of 1 and 2 was tested against tumor cell lines human cervix adenocarcinoma (HeLa), estrogen-receptor-positive human breast cancer (MCF-7), human myelogenous leukemia (K562), and the human Caucasian Burkitt's lymphoma (Ramos). The IC50 values for 1 and 2 were within the range 44.66 +/- 2.39 to 152.40 +/- 2.28M, and from 140.88 +/- 3.51 to 192.05 +/- 2.09M, respectively. Both 1 and 2 were tested for antimicrobial activity. We determined that minimal inhibitory concentration for 1 against Staphylococcus aureus, Bacillus subtilis, and Klebsiella pneumoniae was 25mM. Complex 2 did not express activity against tested microbial strains.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Coordination Chemistry",
title = "Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid",
volume = "71",
number = "10",
pages = "1542-1559",
doi = "10.1080/00958972.2018.1459581"
}

Antonijević-Nikolić, M., Antić-Stanković, J.,& Tanasković, S.. (2018). Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid. in Journal of Coordination Chemistry
Taylor & Francis Ltd, Abingdon., 71(10), 1542-1559.
https://doi.org/10.1080/00958972.2018.1459581

Antonijević-Nikolić M, Antić-Stanković J, Tanasković S. Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid. in Journal of Coordination Chemistry. 2018;71(10):1542-1559.
doi:10.1080/00958972.2018.1459581 .

Antonijević-Nikolić, Mirjana, Antić-Stanković, Jelena, Tanasković, Slađana, "Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid" in Journal of Coordination Chemistry, 71, no. 10 (2018):1542-1559,
https://doi.org/10.1080/00958972.2018.1459581 . .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Antonijević-Nikolić, Mirjana
AU  - Dražić, Branka
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3113
AB  - A new complexes with general formula [Co2(X)2tpmc](BF4)2·Y (X= F-, Y=CH3CN; X= Br-, Y= H2O; tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane), were isolated and their composition, some of physical and chemical properties and their tentative geometries were evaluated based on: elemental analysis (C, H, N), conductometric and magnetic measurements, spectroscopic data (UV/Vis, IR) respectively. Then, we compared synthesized complexes with early described chloro analogous. Both complexes are binuclear with proposed chair conformation of macrocycle. Complex compounds were also preliminary assayed in vitro toward some Gram (+) and Gram (-) bacteria, fungi and mould together with the starting material for the synthesis (ligands, simple salts and solvents) as test substances. In some cases certain antimicrobial activity of the complexes was detected. Minimal inhibitory concentration suppressing the visible growth of bacteria was determined. Both investigated complexes showed a moderate activity against strains of bacteria and were inactive against the tested fungi and mould. Under the same conditions and applied the same concentration of the control group did not show activity.
AB  - Pripremlljena su dva nova kompleksa opšte formule [Co2(X)2tpmc](BF4)2·Y (X= F-, Y=CH3CN; X= Br-, Y= H2O; tpmc = N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11- tetraazaciklotetradekan), čiji su sastav, neke fizičke i hemijske osobine kao i približne geometrije određene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja i spektroskopskih podataka (UV/Vis, IR). Podaci su upoređeni sa ranije sintetisanim i opisanim hloro analogom. Oba nova kompleksa Co(II) su dinuklearna sa pretpostavljenom egzo koordinacijom makrocikla u konformaciji stolice. Kompleksi su preliminarno testirani na neke Gram (+), Gram (-) bakterije, plesni i kvasce zajedno sa startnim supstancama za sintezu (ligandima, prostim solima i rastvaračima) koje su služile kao test supstance. Određivana je minimalna inhibitorna koncentracija koja sprečava rast bakterija. U nekim slučajevima je nađena izvesna antimikrobna aktivnost. Oba kompleksa su pokazala aktivnost prema bakterijama ali su inaktivni prema gljivicama i kvascima dok je pod istim uslovima i istim primenjenim koncentracijama kontrolna grupa bila neaktivna.
PB  - Inženjersko društvo za koroziju, Beograd
T2  - Zaštita materijala
T1  - New mixed ligand Co(II) complexes: Synthesis, characterization and antimicrobial activity
T1  - Novi mešovito-ligandni kompleksi Co (II)- sinteza, karakterizacija i antimikrobna aktivnost
VL  - 59
IS  - 1
SP  - 51
EP  - 55
DO  - 10.5937/ZasMat1801051T
ER  - 

@article{
author = "Tanasković, Slađana and Antonijević-Nikolić, Mirjana and Dražić, Branka",
year = "2018",
abstract = "A new complexes with general formula [Co2(X)2tpmc](BF4)2·Y (X= F-, Y=CH3CN; X= Br-, Y= H2O; tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane), were isolated and their composition, some of physical and chemical properties and their tentative geometries were evaluated based on: elemental analysis (C, H, N), conductometric and magnetic measurements, spectroscopic data (UV/Vis, IR) respectively. Then, we compared synthesized complexes with early described chloro analogous. Both complexes are binuclear with proposed chair conformation of macrocycle. Complex compounds were also preliminary assayed in vitro toward some Gram (+) and Gram (-) bacteria, fungi and mould together with the starting material for the synthesis (ligands, simple salts and solvents) as test substances. In some cases certain antimicrobial activity of the complexes was detected. Minimal inhibitory concentration suppressing the visible growth of bacteria was determined. Both investigated complexes showed a moderate activity against strains of bacteria and were inactive against the tested fungi and mould. Under the same conditions and applied the same concentration of the control group did not show activity., Pripremlljena su dva nova kompleksa opšte formule [Co2(X)2tpmc](BF4)2·Y (X= F-, Y=CH3CN; X= Br-, Y= H2O; tpmc = N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11- tetraazaciklotetradekan), čiji su sastav, neke fizičke i hemijske osobine kao i približne geometrije određene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja i spektroskopskih podataka (UV/Vis, IR). Podaci su upoređeni sa ranije sintetisanim i opisanim hloro analogom. Oba nova kompleksa Co(II) su dinuklearna sa pretpostavljenom egzo koordinacijom makrocikla u konformaciji stolice. Kompleksi su preliminarno testirani na neke Gram (+), Gram (-) bakterije, plesni i kvasce zajedno sa startnim supstancama za sintezu (ligandima, prostim solima i rastvaračima) koje su služile kao test supstance. Određivana je minimalna inhibitorna koncentracija koja sprečava rast bakterija. U nekim slučajevima je nađena izvesna antimikrobna aktivnost. Oba kompleksa su pokazala aktivnost prema bakterijama ali su inaktivni prema gljivicama i kvascima dok je pod istim uslovima i istim primenjenim koncentracijama kontrolna grupa bila neaktivna.",
publisher = "Inženjersko društvo za koroziju, Beograd",
journal = "Zaštita materijala",
title = "New mixed ligand Co(II) complexes: Synthesis, characterization and antimicrobial activity, Novi mešovito-ligandni kompleksi Co (II)- sinteza, karakterizacija i antimikrobna aktivnost",
volume = "59",
number = "1",
pages = "51-55",
doi = "10.5937/ZasMat1801051T"
}

Tanasković, S., Antonijević-Nikolić, M.,& Dražić, B.. (2018). New mixed ligand Co(II) complexes: Synthesis, characterization and antimicrobial activity. in Zaštita materijala
Inženjersko društvo za koroziju, Beograd., 59(1), 51-55.
https://doi.org/10.5937/ZasMat1801051T

Tanasković S, Antonijević-Nikolić M, Dražić B. New mixed ligand Co(II) complexes: Synthesis, characterization and antimicrobial activity. in Zaštita materijala. 2018;59(1):51-55.
doi:10.5937/ZasMat1801051T .

Tanasković, Slađana, Antonijević-Nikolić, Mirjana, Dražić, Branka, "New mixed ligand Co(II) complexes: Synthesis, characterization and antimicrobial activity" in Zaštita materijala, 59, no. 1 (2018):51-55,
https://doi.org/10.5937/ZasMat1801051T . .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Antonijević-Nikolić, Mirjana
AU  - Dražić, Branka
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2834
AB  - The aim of this paper is to compare the efficiency of some analogue of Co (II) and Cu (II) complexes to bacteria pathogenic to humans, which can contaminate vegetables and fruit at any stage of its production. The complexes of Cu(II) and Co(II) with N, N’, N’’, N’’’ - tetrakis (2-pyridylmethyl) -1,4,8,11-tetraazacyclotetradecane (tpmc) and various additional ligands were tested against Gram (+) and Gram (-) bacteria and some strains of fungi. As a control group the free salts of Co(II) and Cu(II) which were used as starting substances in the synthesis, as well as ligands and solvents were tested. The minimum inhibition concentrations suppressing the visible growth of bacteria (MIC) were also screened. Investigated complexes showed a moderate activity against strains of bacteria. Complexes of Co(II) generally showed higher activity then Cu(II) analogues. Under the same conditions and the same concentrations, the control group showed no activity. No compound showed antifungal activity.
AB  - Cilj ovog rada je poređenje efikasnosti nekih analognih kompleksa Co(II) i Cu(II) na bakterijske vrste patogene za čoveka koje mogu kontaminirati povrće i voće u bilo kojoj fazi njegove proizvodnje. Kompleksi Cu (II) i Co (II) sa N, N’, N’’, N’’’ - tetrakis (2-piridilmetil) -1,4,8,11-tetraazaciklotetradekanom (tpmc) i različitim dodatnim ligandima su testirani na Gram (+) i Gram (-) bakterije i neke sojeve gljiva. Kao kontrolna grupa su testirane i proste soli Co(II) i Cu(II) koje su korišćene kao polazne supstance u sintezi kao i ligandi i rastvarači. Određene su minimalne inhibitorne koncentracije (MIC) koje sprečavaju rast mikroorganizama. Ispitivani kompleksi pokazuju umerenu aktivnost prema sojevima bakterija. Kompleksi Co(II) su pokazali generalno već u aktivnost u odnosu na Cu (II) analoge. Pod istim uslovima i u primenjenim istim koncentracijama kontrolne grupe nisu pokazale aktivnost. Nijedno jedinjenje nije ispoljilo antigljivično dejstvo.
PB  - Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za zaštitu bilja i životne sredine "dr Pavla Vukasovića", Novi Sad
T2  - Biljni lekar
T1  - Comparison of the antimicrobial activity of related Co(II)/Cu(II) complexes
T1  - Uporedni prikaz antimikrobne aktivnosti srodnih Co(II)/Cu(II) kompleksa
VL  - 45
IS  - 3
SP  - 321
EP  - 325
UR  - https://hdl.handle.net/21.15107/rcub_farfar_2834
ER  - 

@article{
author = "Tanasković, Slađana and Antonijević-Nikolić, Mirjana and Dražić, Branka",
year = "2017",
abstract = "The aim of this paper is to compare the efficiency of some analogue of Co (II) and Cu (II) complexes to bacteria pathogenic to humans, which can contaminate vegetables and fruit at any stage of its production. The complexes of Cu(II) and Co(II) with N, N’, N’’, N’’’ - tetrakis (2-pyridylmethyl) -1,4,8,11-tetraazacyclotetradecane (tpmc) and various additional ligands were tested against Gram (+) and Gram (-) bacteria and some strains of fungi. As a control group the free salts of Co(II) and Cu(II) which were used as starting substances in the synthesis, as well as ligands and solvents were tested. The minimum inhibition concentrations suppressing the visible growth of bacteria (MIC) were also screened. Investigated complexes showed a moderate activity against strains of bacteria. Complexes of Co(II) generally showed higher activity then Cu(II) analogues. Under the same conditions and the same concentrations, the control group showed no activity. No compound showed antifungal activity., Cilj ovog rada je poređenje efikasnosti nekih analognih kompleksa Co(II) i Cu(II) na bakterijske vrste patogene za čoveka koje mogu kontaminirati povrće i voće u bilo kojoj fazi njegove proizvodnje. Kompleksi Cu (II) i Co (II) sa N, N’, N’’, N’’’ - tetrakis (2-piridilmetil) -1,4,8,11-tetraazaciklotetradekanom (tpmc) i različitim dodatnim ligandima su testirani na Gram (+) i Gram (-) bakterije i neke sojeve gljiva. Kao kontrolna grupa su testirane i proste soli Co(II) i Cu(II) koje su korišćene kao polazne supstance u sintezi kao i ligandi i rastvarači. Određene su minimalne inhibitorne koncentracije (MIC) koje sprečavaju rast mikroorganizama. Ispitivani kompleksi pokazuju umerenu aktivnost prema sojevima bakterija. Kompleksi Co(II) su pokazali generalno već u aktivnost u odnosu na Cu (II) analoge. Pod istim uslovima i u primenjenim istim koncentracijama kontrolne grupe nisu pokazale aktivnost. Nijedno jedinjenje nije ispoljilo antigljivično dejstvo.",
publisher = "Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za zaštitu bilja i životne sredine "dr Pavla Vukasovića", Novi Sad",
journal = "Biljni lekar",
title = "Comparison of the antimicrobial activity of related Co(II)/Cu(II) complexes, Uporedni prikaz antimikrobne aktivnosti srodnih Co(II)/Cu(II) kompleksa",
volume = "45",
number = "3",
pages = "321-325",
url = "https://hdl.handle.net/21.15107/rcub_farfar_2834"
}

Tanasković, S., Antonijević-Nikolić, M.,& Dražić, B.. (2017). Comparison of the antimicrobial activity of related Co(II)/Cu(II) complexes. in Biljni lekar
Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za zaštitu bilja i životne sredine "dr Pavla Vukasovića", Novi Sad., 45(3), 321-325.
https://hdl.handle.net/21.15107/rcub_farfar_2834

Tanasković S, Antonijević-Nikolić M, Dražić B. Comparison of the antimicrobial activity of related Co(II)/Cu(II) complexes. in Biljni lekar. 2017;45(3):321-325.
https://hdl.handle.net/21.15107/rcub_farfar_2834 .

Tanasković, Slađana, Antonijević-Nikolić, Mirjana, Dražić, Branka, "Comparison of the antimicrobial activity of related Co(II)/Cu(II) complexes" in Biljni lekar, 45, no. 3 (2017):321-325,
https://hdl.handle.net/21.15107/rcub_farfar_2834 .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Antonijević-Nikolić, Mirjana
AU  - Hollo, Berta Barta
AU  - Dražić, Branka
AU  - Stanojković, Tatjana
AU  - Meszaros-Szecsenyi, Katalin
AU  - Vucković, Gordana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2131
AB  - Seven macrocyclic dinuclear Cu(II) complexes with tpmc = = N,N ',N '',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane of coordination formulae [Cu(2)tpmc](ClO4)(4) (1), [Cu-2(X)tpmc](ClO4)(3)center dot nH(2)O, X= F-, n = 0 (2), X = Cl-, n = 1 (3), X = Br-, n = 0 (4), X= I-, n = 1 (5), X = = NO2-, n = 0 (6), [Cu-2(NCS)(2)tpmc](ClO4)(2) (7) were evaluated for their cytotoxic activity against human cervix adenocarcinoma (HeLa), human melanoma (Fem-x) and human colon carcinoma (LS174) cell lines. The results were compared with the corresponding data for the cis-diamminedichloridoplafinum(H) (CDDP) as referent cytostatic, as well as with the free ligands and the solvent dimethyl sulfoxide (DMSO) as controls. The complexes showed considerable antiproliferative effect, although significantly less than CDDP. The thermal decomposition pattern of the complexes was determined by simultaneous TG/DSC measurements. The thermal stability of the compounds 2-7 followed the trend of their antiproliferative activity against the HeLa cell line, as well as their corresponding stability constants. The highest thermal stability and cytotoxicity belonged to complex [Cu(2)tpmc](ClO4)(4), with no anionic co-ligand. Complex [Cu-2(NO2)tpmc](ClO4)(3) exhibited a selective cytotoxicity against LS174 cells, at the level of the most active [Cu(2)tpmc](ClO4)(4).
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Correlations between the in vitro antiproliferative activity, structure and thermal stability of some macrocyclic dinuclear Cu(II) complexes
VL  - 79
IS  - 10
SP  - 1235
EP  - 1247
DO  - 10.2298/JSC140404044T
ER  - 

@article{
author = "Tanasković, Slađana and Antonijević-Nikolić, Mirjana and Hollo, Berta Barta and Dražić, Branka and Stanojković, Tatjana and Meszaros-Szecsenyi, Katalin and Vucković, Gordana",
year = "2014",
abstract = "Seven macrocyclic dinuclear Cu(II) complexes with tpmc = = N,N ',N '',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane of coordination formulae [Cu(2)tpmc](ClO4)(4) (1), [Cu-2(X)tpmc](ClO4)(3)center dot nH(2)O, X= F-, n = 0 (2), X = Cl-, n = 1 (3), X = Br-, n = 0 (4), X= I-, n = 1 (5), X = = NO2-, n = 0 (6), [Cu-2(NCS)(2)tpmc](ClO4)(2) (7) were evaluated for their cytotoxic activity against human cervix adenocarcinoma (HeLa), human melanoma (Fem-x) and human colon carcinoma (LS174) cell lines. The results were compared with the corresponding data for the cis-diamminedichloridoplafinum(H) (CDDP) as referent cytostatic, as well as with the free ligands and the solvent dimethyl sulfoxide (DMSO) as controls. The complexes showed considerable antiproliferative effect, although significantly less than CDDP. The thermal decomposition pattern of the complexes was determined by simultaneous TG/DSC measurements. The thermal stability of the compounds 2-7 followed the trend of their antiproliferative activity against the HeLa cell line, as well as their corresponding stability constants. The highest thermal stability and cytotoxicity belonged to complex [Cu(2)tpmc](ClO4)(4), with no anionic co-ligand. Complex [Cu-2(NO2)tpmc](ClO4)(3) exhibited a selective cytotoxicity against LS174 cells, at the level of the most active [Cu(2)tpmc](ClO4)(4).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Correlations between the in vitro antiproliferative activity, structure and thermal stability of some macrocyclic dinuclear Cu(II) complexes",
volume = "79",
number = "10",
pages = "1235-1247",
doi = "10.2298/JSC140404044T"
}

Tanasković, S., Antonijević-Nikolić, M., Hollo, B. B., Dražić, B., Stanojković, T., Meszaros-Szecsenyi, K.,& Vucković, G.. (2014). Correlations between the in vitro antiproliferative activity, structure and thermal stability of some macrocyclic dinuclear Cu(II) complexes. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 79(10), 1235-1247.
https://doi.org/10.2298/JSC140404044T

Tanasković S, Antonijević-Nikolić M, Hollo BB, Dražić B, Stanojković T, Meszaros-Szecsenyi K, Vucković G. Correlations between the in vitro antiproliferative activity, structure and thermal stability of some macrocyclic dinuclear Cu(II) complexes. in Journal of the Serbian Chemical Society. 2014;79(10):1235-1247.
doi:10.2298/JSC140404044T .

Tanasković, Slađana, Antonijević-Nikolić, Mirjana, Hollo, Berta Barta, Dražić, Branka, Stanojković, Tatjana, Meszaros-Szecsenyi, Katalin, Vucković, Gordana, "Correlations between the in vitro antiproliferative activity, structure and thermal stability of some macrocyclic dinuclear Cu(II) complexes" in Journal of the Serbian Chemical Society, 79, no. 10 (2014):1235-1247,
https://doi.org/10.2298/JSC140404044T . .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Antić-Stanković, Jelena
AU  - Antonijević-Nikolić, Mirjana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2039
AB  - Four cationic mixed-ligand complexes of Cu (II) with N, N', N'', N''' -tetrakis (2-pyridylmethyl) -1,4,8,11 -tetraazacyclotetradecane (tpmc) and aliphatic dicarboxylic acids: succinic, glutaric , adipic and sebacic were investigated in vitro on the human cervix adenocarcinoma (HeLa), human malignant melanoma (Fem-x), oestrogen-receptor-positive human breast cancer (MCF-7) cells and the human acute monocyte leukemia cell line (THP1), while free ligands, Cu(II) salt and solvent (used as a controls) were inactive on the same conditions. The metabolic activity of the cells was determined by tetrazolium MTS test. All complexes showed cytotoxicity toward the used cell lines, while free ligands, Cu(II) salt and solvent (used as a controls) were inactive on the same conditions. Increasing the number of - CH2- groups in homologous serie of aliphatic dicarboxylate ligands leads to the increasing cytotoxic activity of the complex. The highest cytotoxic effect of azamacrocycle Cu(II) complexes with glutarate, adipate, sebacinate ligand showed on the cell line MCF-7 and the worst on HeLa cells. A significant effect of sebacinate Cu(II)complex to all tested tumor cell lines applied in concentrations of 100 and 200 μM and up to HeLa cells.
AB  - Četiri katjonska mešovito-ligandna kompleksa Cu(II) sa N,N',N'N''-tetrakis(2- piridilmetil)-1,4,8,11-tetraaza-ciklotetradekanom i alifatičnim dikarboksilatima: ćilibarnom, glutarnom, adipinskom i sebacinskom kiselinom su ispitivani na humanim malignim ćelijskim linijama: cervikalnog adenokarcinoma (HeLa), melanoma (Fem-X), estrogen pozitivnog karcinoma dojke (MCF-7) i akutne monocitne leukemjie (THP1). Uporedo su testirani i sami ligandi, proste soli i rastvarači. Metabolička aktivnost ćelija je određena MTS testom. Svi ispitivani kompleksi su pokazali citotoksični efekat prema testiranim ćelijskim linijama, dok su slobodni ligandi, Cu(II) so i rastvarač (koji su korišćeni kao kontrolni) pod istim uslovima, bili neaktivni. Sa povećanjem broja -CH2- grupa homologog niza alifatičnih dikarboksilato liganada dolazi i do povećane citotoksičnosti kompleksa. Najveći citotoksični efekat su pokazali makrociklični Cu(II) kompleksi sa glutarato, adipato i sebacinato ligandima prema MCF-7, a najslabiji prema HeLa ćelijama. Najveći antiproliferativni efekat pokazuje kompleks sa sebacinato ligandom prema svim testiranim linijama tumorskih ćelija u primenjenim koncentracijama od 100 i 200 μM, a najviše prema HeLa ćelijama.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Antiproliferative activity of mixed-ligand Cu(II) complexes with pendant octaazamacrocycle in vitro
T1  - Antiproliferativna aktivnost mešovito-ligandnih Cu (II) kompleksa sa pendantnim oktaazamakrociklom in vitro
VL  - 63
IS  - 4
SP  - 365
EP  - 374
UR  - https://hdl.handle.net/21.15107/rcub_farfar_2039
ER  - 

@article{
author = "Tanasković, Slađana and Antić-Stanković, Jelena and Antonijević-Nikolić, Mirjana",
year = "2013",
abstract = "Four cationic mixed-ligand complexes of Cu (II) with N, N', N'', N''' -tetrakis (2-pyridylmethyl) -1,4,8,11 -tetraazacyclotetradecane (tpmc) and aliphatic dicarboxylic acids: succinic, glutaric , adipic and sebacic were investigated in vitro on the human cervix adenocarcinoma (HeLa), human malignant melanoma (Fem-x), oestrogen-receptor-positive human breast cancer (MCF-7) cells and the human acute monocyte leukemia cell line (THP1), while free ligands, Cu(II) salt and solvent (used as a controls) were inactive on the same conditions. The metabolic activity of the cells was determined by tetrazolium MTS test. All complexes showed cytotoxicity toward the used cell lines, while free ligands, Cu(II) salt and solvent (used as a controls) were inactive on the same conditions. Increasing the number of - CH2- groups in homologous serie of aliphatic dicarboxylate ligands leads to the increasing cytotoxic activity of the complex. The highest cytotoxic effect of azamacrocycle Cu(II) complexes with glutarate, adipate, sebacinate ligand showed on the cell line MCF-7 and the worst on HeLa cells. A significant effect of sebacinate Cu(II)complex to all tested tumor cell lines applied in concentrations of 100 and 200 μM and up to HeLa cells., Četiri katjonska mešovito-ligandna kompleksa Cu(II) sa N,N',N'N''-tetrakis(2- piridilmetil)-1,4,8,11-tetraaza-ciklotetradekanom i alifatičnim dikarboksilatima: ćilibarnom, glutarnom, adipinskom i sebacinskom kiselinom su ispitivani na humanim malignim ćelijskim linijama: cervikalnog adenokarcinoma (HeLa), melanoma (Fem-X), estrogen pozitivnog karcinoma dojke (MCF-7) i akutne monocitne leukemjie (THP1). Uporedo su testirani i sami ligandi, proste soli i rastvarači. Metabolička aktivnost ćelija je određena MTS testom. Svi ispitivani kompleksi su pokazali citotoksični efekat prema testiranim ćelijskim linijama, dok su slobodni ligandi, Cu(II) so i rastvarač (koji su korišćeni kao kontrolni) pod istim uslovima, bili neaktivni. Sa povećanjem broja -CH2- grupa homologog niza alifatičnih dikarboksilato liganada dolazi i do povećane citotoksičnosti kompleksa. Najveći citotoksični efekat su pokazali makrociklični Cu(II) kompleksi sa glutarato, adipato i sebacinato ligandima prema MCF-7, a najslabiji prema HeLa ćelijama. Najveći antiproliferativni efekat pokazuje kompleks sa sebacinato ligandom prema svim testiranim linijama tumorskih ćelija u primenjenim koncentracijama od 100 i 200 μM, a najviše prema HeLa ćelijama.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Antiproliferative activity of mixed-ligand Cu(II) complexes with pendant octaazamacrocycle in vitro, Antiproliferativna aktivnost mešovito-ligandnih Cu (II) kompleksa sa pendantnim oktaazamakrociklom in vitro",
volume = "63",
number = "4",
pages = "365-374",
url = "https://hdl.handle.net/21.15107/rcub_farfar_2039"
}

Tanasković, S., Antić-Stanković, J.,& Antonijević-Nikolić, M.. (2013). Antiproliferative activity of mixed-ligand Cu(II) complexes with pendant octaazamacrocycle in vitro. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 63(4), 365-374.
https://hdl.handle.net/21.15107/rcub_farfar_2039

Tanasković S, Antić-Stanković J, Antonijević-Nikolić M. Antiproliferative activity of mixed-ligand Cu(II) complexes with pendant octaazamacrocycle in vitro. in Arhiv za farmaciju. 2013;63(4):365-374.
https://hdl.handle.net/21.15107/rcub_farfar_2039 .

Tanasković, Slađana, Antić-Stanković, Jelena, Antonijević-Nikolić, Mirjana, "Antiproliferative activity of mixed-ligand Cu(II) complexes with pendant octaazamacrocycle in vitro" in Arhiv za farmaciju, 63, no. 4 (2013):365-374,
https://hdl.handle.net/21.15107/rcub_farfar_2039 .

TY  - JOUR
AU  - Antonijević-Nikolić, Mirjana
AU  - Antić-Stanković, Jelena
AU  - Tanasković, Slađana
AU  - Korabik, Maria J.
AU  - Gojgić-Cvijović, Gordana
AU  - Vucković, Gordana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1907
AB  - New cationic Cu(II) complexes with N, N', N '', N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and aliphatic dicarboxylic acids: pentanedioic (glutaric acid = glutH(2)), hexanedioic acid (adipic acid = adipH(2)) and decanedioic acid (sebacic acid = sebH(2)) of general formula [Cu-4(L)(tpmc)(2)] (ClO4)(6)center dot xH(2)O, L = glut, x = 2; L = adip, x = 7; L = seb, x = 6 were isolated. Their composition and charges are proposed based on elemental analyses and molar conductivity measurements. By the comparison of their UV-Vis, reflectance, FTIR and EPR spectral data, CV and SQUID magnetic measurements, with those for the complex with butanedioic acid (succinic acid = succH(2)) of known molecular structure and analysis of LC/MS spectra, geometry with two [Cu(2)tpmc](4) units bridged by dicarboxylate dianion engaging all oxygens is proposed. Within units, Cu(II) ions are also bridged with -N- portion of cyclam ring. All four complexes were screened to in vitro antimicrobial and cytotoxic activity along with free primary and secondary ligands, Cu(II) salt and solvent controls. Detected antibacterial and cytotoxic activity for the complexes was enhanced in most cases than the corresponding controls.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Molecular Structure
T1  - Preparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexes
VL  - 1054
SP  - 297
EP  - 306
DO  - 10.1016/j.molstruc.2013.10.006
ER  - 

@article{
author = "Antonijević-Nikolić, Mirjana and Antić-Stanković, Jelena and Tanasković, Slađana and Korabik, Maria J. and Gojgić-Cvijović, Gordana and Vucković, Gordana",
year = "2013",
abstract = "New cationic Cu(II) complexes with N, N', N '', N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and aliphatic dicarboxylic acids: pentanedioic (glutaric acid = glutH(2)), hexanedioic acid (adipic acid = adipH(2)) and decanedioic acid (sebacic acid = sebH(2)) of general formula [Cu-4(L)(tpmc)(2)] (ClO4)(6)center dot xH(2)O, L = glut, x = 2; L = adip, x = 7; L = seb, x = 6 were isolated. Their composition and charges are proposed based on elemental analyses and molar conductivity measurements. By the comparison of their UV-Vis, reflectance, FTIR and EPR spectral data, CV and SQUID magnetic measurements, with those for the complex with butanedioic acid (succinic acid = succH(2)) of known molecular structure and analysis of LC/MS spectra, geometry with two [Cu(2)tpmc](4) units bridged by dicarboxylate dianion engaging all oxygens is proposed. Within units, Cu(II) ions are also bridged with -N- portion of cyclam ring. All four complexes were screened to in vitro antimicrobial and cytotoxic activity along with free primary and secondary ligands, Cu(II) salt and solvent controls. Detected antibacterial and cytotoxic activity for the complexes was enhanced in most cases than the corresponding controls.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Molecular Structure",
title = "Preparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexes",
volume = "1054",
pages = "297-306",
doi = "10.1016/j.molstruc.2013.10.006"
}

Antonijević-Nikolić, M., Antić-Stanković, J., Tanasković, S., Korabik, M. J., Gojgić-Cvijović, G.,& Vucković, G.. (2013). Preparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexes. in Journal of Molecular Structure
Elsevier Science BV, Amsterdam., 1054, 297-306.
https://doi.org/10.1016/j.molstruc.2013.10.006

Antonijević-Nikolić M, Antić-Stanković J, Tanasković S, Korabik MJ, Gojgić-Cvijović G, Vucković G. Preparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexes. in Journal of Molecular Structure. 2013;1054:297-306.
doi:10.1016/j.molstruc.2013.10.006 .

Antonijević-Nikolić, Mirjana, Antić-Stanković, Jelena, Tanasković, Slađana, Korabik, Maria J., Gojgić-Cvijović, Gordana, Vucković, Gordana, "Preparation, characterisation and study of in vitro biologically active azamacrocyclic Cu(II) dicarboxylate complexes" in Journal of Molecular Structure, 1054 (2013):297-306,
https://doi.org/10.1016/j.molstruc.2013.10.006 . .

TY  - JOUR
AU  - Tanasković, Slađana
AU  - Vucković, Gordana
AU  - Antonijević-Nikolić, Mirjana
AU  - Stanojković, Tatjana
AU  - Gojgić-Cvijović, Gordana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1674
AB  - Four new cationic Co(II) complexes with N,N',N '',N'''-tetrakis (2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and dianion of one the aliphatic dicarboxylic acids: butanedioic acid (succinic) acid = succH(2), pentanedioic (glutaric) acid = gluH(2), hexanedioic acid (adipic) acid = adipH(2) or decanedioic acid (sebacic) acid = sebH(2) of general formula [Co-2(L)(tpmc)](ClO4)(2)center dot xY, L2- = succ, x = 1, Y = H2O; L = glu, x = 1, Y = H2O; L = adip, x = 1.5, Y = H2O; L = seb, x = 1, Y = CH3CN were isolated. The composition and charge are proposed based on elemental analyses (C, H. N) and electrical conductivity measurements. UV-Vis and FTIR spectral data and magnetic moments were in accordance with high-spin Co(II) state. It is proposed that in all complexes Co(II) is hexa-coordinated out of cyclam ring and that both carboxylic groups from dicarboxylate bridge participate in coordination. Oxygens from one group are most likely bonded to the same Co(II) ion thus forming a four-membered ring. The in vitro antibacterial/antiproliferative activities of the complexes were in some cases enhanced compared with the simple Co(II) salt and free ligands, tested as controls.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Molecular Structure
T1  - Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates
VL  - 1029
SP  - 1
EP  - 7
DO  - 10.1016/j.molstruc.2012.06.055
ER  - 

@article{
author = "Tanasković, Slađana and Vucković, Gordana and Antonijević-Nikolić, Mirjana and Stanojković, Tatjana and Gojgić-Cvijović, Gordana",
year = "2012",
abstract = "Four new cationic Co(II) complexes with N,N',N '',N'''-tetrakis (2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and dianion of one the aliphatic dicarboxylic acids: butanedioic acid (succinic) acid = succH(2), pentanedioic (glutaric) acid = gluH(2), hexanedioic acid (adipic) acid = adipH(2) or decanedioic acid (sebacic) acid = sebH(2) of general formula [Co-2(L)(tpmc)](ClO4)(2)center dot xY, L2- = succ, x = 1, Y = H2O; L = glu, x = 1, Y = H2O; L = adip, x = 1.5, Y = H2O; L = seb, x = 1, Y = CH3CN were isolated. The composition and charge are proposed based on elemental analyses (C, H. N) and electrical conductivity measurements. UV-Vis and FTIR spectral data and magnetic moments were in accordance with high-spin Co(II) state. It is proposed that in all complexes Co(II) is hexa-coordinated out of cyclam ring and that both carboxylic groups from dicarboxylate bridge participate in coordination. Oxygens from one group are most likely bonded to the same Co(II) ion thus forming a four-membered ring. The in vitro antibacterial/antiproliferative activities of the complexes were in some cases enhanced compared with the simple Co(II) salt and free ligands, tested as controls.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Molecular Structure",
title = "Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates",
volume = "1029",
pages = "1-7",
doi = "10.1016/j.molstruc.2012.06.055"
}

Tanasković, S., Vucković, G., Antonijević-Nikolić, M., Stanojković, T.,& Gojgić-Cvijović, G.. (2012). Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates. in Journal of Molecular Structure
Elsevier Science BV, Amsterdam., 1029, 1-7.
https://doi.org/10.1016/j.molstruc.2012.06.055

Tanasković S, Vucković G, Antonijević-Nikolić M, Stanojković T, Gojgić-Cvijović G. Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates. in Journal of Molecular Structure. 2012;1029:1-7.
doi:10.1016/j.molstruc.2012.06.055 .

Tanasković, Slađana, Vucković, Gordana, Antonijević-Nikolić, Mirjana, Stanojković, Tatjana, Gojgić-Cvijović, Gordana, "Binuclear biologically active Co(II) complexes with octazamacrocycle and aliphatic dicarboxylates" in Journal of Molecular Structure, 1029 (2012):1-7,
https://doi.org/10.1016/j.molstruc.2012.06.055 . .

TY  - JOUR
AU  - Vučković, Gordana
AU  - Antonijević-Nikolić, Mirjana
AU  - Tanasković, Slađana
AU  - Živković-Radovanović, Vukosava
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1611
AB  - New cationic Cu(II) and Co(II) complexes with N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and the anion of 2-amino-3-phenylpropanoic acid (S-phenylalanine) were prepared. The complexes were analyzed and characterized by elemental analysis, conducto-metric, polarimetric, magnetic and cyclic voltammetric measurements, as well as by spectroscopic data (UV/Vis, IR). Both complexes are binuclear with the general formula [M2(S-Phe)tpmc](ClO4)3·nH2O; S-PheH = S-phenylalanine, M(II)= Cu, n = 7; Co, n = 0. Based on previously reported data for some familiar complexes and the present results, pentacoordinated geometry was proposed. Both of the central metal ions are coordinated with two pyridyl and two cyclam nitrogens and bridged with -N-(CH2)3-N-portions of the cyclam ring and oxygen atoms of the S-phenylalaninate ion. Antimicrobial screening of the complexes, solvent, starting salts and ligands alone was performed against fungi, mould and some bacteria. In certain cases, enhanced activity of Co(II) complex towards bacteria compared with the relevant free ligands and starting salts was detected.
AB  - Dobijena su dva nova kompleksa Cu(II) i Co(II) sa N,N',N',N'''-tetrakis(2-piridilmetil)-1,4,8,11-ciklotetradekanom (tpmc-om) i anjonom 2-amino-3-fenil-propanske kiseline (S-fenilalanina). Oni su analizirani i okarakterisani: elementalnom analizom, konduktometrijskim, polarimetrijskim, magnetnim i ciklično-voltametrijskim merenjima, kao i spektroskopskim podacima (UV/Vis, IR). Oba kompleksa su dinuklearna opšte formule [M2(S-Phe)tpmc](ClO4)3·nH2O; S-PheH = S-fenilalanin, M(II) = Cu, n = 7; Co, n = 0. Na osnovu ranije dobijenih podataka za srodne komplekse i novih rezultata pretpostavljena je pentakoordinaciona geometrija. Oba centralna metalna jona su koordinovana za po dva piridil i dva ciklamova azota i premošćena -N-(CH2)3-N-fragmentima ciklamovog prstena i kiseonikovim atomima S-fenilalaninato jona. Antimikrobni test kompleksa, rastvarača, polaznih soli i samih liganada je izvršen na gljivice, plesni i bakterije. U izvesnim slučajevima nađena je povećana aktivnost kompleksa Co(II) prema pojedinim bakterijama u odnosu na odgovarajuće slobodne ligande i polazne soli.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - New Cu(II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenylpropanoic acid
T1  - Novi Cu(II) i Co(II) oktaazamakrociklični kompleksi sa 2-amino-3-fenil-propanskom kiselinom
VL  - 76
IS  - 5
SP  - 719
EP  - 731
DO  - 10.2298/JSC101201062V
ER  - 

@article{
author = "Vučković, Gordana and Antonijević-Nikolić, Mirjana and Tanasković, Slađana and Živković-Radovanović, Vukosava",
year = "2011",
abstract = "New cationic Cu(II) and Co(II) complexes with N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc) and the anion of 2-amino-3-phenylpropanoic acid (S-phenylalanine) were prepared. The complexes were analyzed and characterized by elemental analysis, conducto-metric, polarimetric, magnetic and cyclic voltammetric measurements, as well as by spectroscopic data (UV/Vis, IR). Both complexes are binuclear with the general formula [M2(S-Phe)tpmc](ClO4)3·nH2O; S-PheH = S-phenylalanine, M(II)= Cu, n = 7; Co, n = 0. Based on previously reported data for some familiar complexes and the present results, pentacoordinated geometry was proposed. Both of the central metal ions are coordinated with two pyridyl and two cyclam nitrogens and bridged with -N-(CH2)3-N-portions of the cyclam ring and oxygen atoms of the S-phenylalaninate ion. Antimicrobial screening of the complexes, solvent, starting salts and ligands alone was performed against fungi, mould and some bacteria. In certain cases, enhanced activity of Co(II) complex towards bacteria compared with the relevant free ligands and starting salts was detected., Dobijena su dva nova kompleksa Cu(II) i Co(II) sa N,N',N',N'''-tetrakis(2-piridilmetil)-1,4,8,11-ciklotetradekanom (tpmc-om) i anjonom 2-amino-3-fenil-propanske kiseline (S-fenilalanina). Oni su analizirani i okarakterisani: elementalnom analizom, konduktometrijskim, polarimetrijskim, magnetnim i ciklično-voltametrijskim merenjima, kao i spektroskopskim podacima (UV/Vis, IR). Oba kompleksa su dinuklearna opšte formule [M2(S-Phe)tpmc](ClO4)3·nH2O; S-PheH = S-fenilalanin, M(II) = Cu, n = 7; Co, n = 0. Na osnovu ranije dobijenih podataka za srodne komplekse i novih rezultata pretpostavljena je pentakoordinaciona geometrija. Oba centralna metalna jona su koordinovana za po dva piridil i dva ciklamova azota i premošćena -N-(CH2)3-N-fragmentima ciklamovog prstena i kiseonikovim atomima S-fenilalaninato jona. Antimikrobni test kompleksa, rastvarača, polaznih soli i samih liganada je izvršen na gljivice, plesni i bakterije. U izvesnim slučajevima nađena je povećana aktivnost kompleksa Co(II) prema pojedinim bakterijama u odnosu na odgovarajuće slobodne ligande i polazne soli.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "New Cu(II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenylpropanoic acid, Novi Cu(II) i Co(II) oktaazamakrociklični kompleksi sa 2-amino-3-fenil-propanskom kiselinom",
volume = "76",
number = "5",
pages = "719-731",
doi = "10.2298/JSC101201062V"
}

Vučković, G., Antonijević-Nikolić, M., Tanasković, S.,& Živković-Radovanović, V.. (2011). New Cu(II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenylpropanoic acid. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 76(5), 719-731.
https://doi.org/10.2298/JSC101201062V

Vučković G, Antonijević-Nikolić M, Tanasković S, Živković-Radovanović V. New Cu(II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenylpropanoic acid. in Journal of the Serbian Chemical Society. 2011;76(5):719-731.
doi:10.2298/JSC101201062V .

Vučković, Gordana, Antonijević-Nikolić, Mirjana, Tanasković, Slađana, Živković-Radovanović, Vukosava, "New Cu(II) and Co(II) octaazamacrocyclic complexes with 2-amino-3-phenylpropanoic acid" in Journal of the Serbian Chemical Society, 76, no. 5 (2011):719-731,
https://doi.org/10.2298/JSC101201062V . .

TY  - JOUR
AU  - Vučković, Gordana
AU  - Tanasković, Slađana
AU  - Antonijević-Nikolić, Mirjana
AU  - Živković-Radovanović, Vukosava
AU  - Gojgić-Cvijović, Gordana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1295
AB  - Four new air-stable mixed-ligand Co(II) complexes having the general formula [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-methylglycine/N,N-dimethylglycine, Z = - 4BF , qH2O=4 or 3; HY=S-norvaline/S-valine Z=-ClO4 , qCH3CN = 0.5; qH2O = 0.5; tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane) were prepared. The composition, some physical and chemical properties and their tentative geometries were evaluated based on elemental analysis (C, H, N), conductometric and magnetic measurements, spectroscopic data (UV/Vis, IR) and cyclic voltammetry. The data were compared with earlier described analogous complexes containing the macrocyclic ligand and aliphatic aminocarboxylates. It is assumed that all complexes are binuclear with an exo coordination mode of the octaazamacrocyclic pendant ligand in the boat conformation. In addition, two -N-(CH2)2-N- portions of the cyclam ring within the tpmc ligand and Co(II) ions in the high-spin state are most probably bridged via oxygen atoms from the anion of the aminocarboxylate/derivatives, whereas nitrogen atoms rest uncoordinated. In all cases, a combined chelate-bridged coordination is proposed as the most probable. The complexes were electrochemically stable in the potential range -1.0 to 1.0 V. They were also preliminary assayed toward some microorganisms together with the ligands, starting simple salts and solvents as test substances. In some cases, certain antimicrobial activity of the complexes was detected.
AB  - Dobijena su četiri nova mešovito-ligandna kompleksa Co(II), stabilna na vazduhu, opšte formule [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-metilglicin/N,N-dimetilglicin, Z=-4BF , qH2O=4 ili 3); HY = S-norvalin/S-valin, Z=-ClO4, qCH3CN=0,5; qH2O=0,5; tpmc= N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekan). Sastav, neka fizička i hemijska svojstva i njihove približne geometrije su izvedene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja, spektroskopskih podataka (UV/Vis, IR) odnosno ciklične voltametrije. Podaci su upoređeni sa ranije opisanim analogim kompleksima koji sadrže makrociklični ligand i alifatične aminokarboksilate. Pretpostavljeno je da su svi kompleksi dinuklearni sa egzo koordinacijom pendantnog oktaazamakrocikla u konformaciji lađe. Pored dva -N-(CH2)2-N- dela ciklamovog prstena unutar tpmc-a, joni visoko-spinskog Co(II) su najverovatnije premošćeni angažovanjem kiseonikovih atoma sa anjona aminokarboksilata/derivata, dok atomi azota ostaju nekoordinovani. Za sve komplekse predložen je kombinovani helatno-mostovni način vezivanja. Kompleksi su bili elektrohemijski stabilni u opsegu potencijala -1,0 do 1,0 V. Oni su preliminarno testirani na mikroorganizme zajedno sa ligandima, polaznim prostim solima i rastvaračima kao test supstancama. U nekim slučajevima je nađena izvesna antimikrobna aktivnost kompleksa.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives
T1  - Proučavanje novih kompleksa kobalta(II) sa oktaazamakrociklom i aminokarboksilatima ili njihovim derivatima
VL  - 74
IS  - 6
SP  - 629
EP  - 640
DO  - 10.2298/JSC0906629V
ER  - 

@article{
author = "Vučković, Gordana and Tanasković, Slađana and Antonijević-Nikolić, Mirjana and Živković-Radovanović, Vukosava and Gojgić-Cvijović, Gordana",
year = "2009",
abstract = "Four new air-stable mixed-ligand Co(II) complexes having the general formula [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-methylglycine/N,N-dimethylglycine, Z = - 4BF , qH2O=4 or 3; HY=S-norvaline/S-valine Z=-ClO4 , qCH3CN = 0.5; qH2O = 0.5; tpmc = N,N',N'',N'''-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane) were prepared. The composition, some physical and chemical properties and their tentative geometries were evaluated based on elemental analysis (C, H, N), conductometric and magnetic measurements, spectroscopic data (UV/Vis, IR) and cyclic voltammetry. The data were compared with earlier described analogous complexes containing the macrocyclic ligand and aliphatic aminocarboxylates. It is assumed that all complexes are binuclear with an exo coordination mode of the octaazamacrocyclic pendant ligand in the boat conformation. In addition, two -N-(CH2)2-N- portions of the cyclam ring within the tpmc ligand and Co(II) ions in the high-spin state are most probably bridged via oxygen atoms from the anion of the aminocarboxylate/derivatives, whereas nitrogen atoms rest uncoordinated. In all cases, a combined chelate-bridged coordination is proposed as the most probable. The complexes were electrochemically stable in the potential range -1.0 to 1.0 V. They were also preliminary assayed toward some microorganisms together with the ligands, starting simple salts and solvents as test substances. In some cases, certain antimicrobial activity of the complexes was detected., Dobijena su četiri nova mešovito-ligandna kompleksa Co(II), stabilna na vazduhu, opšte formule [Co2(Y)tpmc]Z3×q(H2O/CH3CN) (HY = N-metilglicin/N,N-dimetilglicin, Z=-4BF , qH2O=4 ili 3); HY = S-norvalin/S-valin, Z=-ClO4, qCH3CN=0,5; qH2O=0,5; tpmc= N,N',N'',N'''-tetrakis(2-piridilmetil)-1,4,8,11-tetraazaciklotetradekan). Sastav, neka fizička i hemijska svojstva i njihove približne geometrije su izvedene na osnovu elementalne analize (C, H, N), konduktometrijskih i magnetnih merenja, spektroskopskih podataka (UV/Vis, IR) odnosno ciklične voltametrije. Podaci su upoređeni sa ranije opisanim analogim kompleksima koji sadrže makrociklični ligand i alifatične aminokarboksilate. Pretpostavljeno je da su svi kompleksi dinuklearni sa egzo koordinacijom pendantnog oktaazamakrocikla u konformaciji lađe. Pored dva -N-(CH2)2-N- dela ciklamovog prstena unutar tpmc-a, joni visoko-spinskog Co(II) su najverovatnije premošćeni angažovanjem kiseonikovih atoma sa anjona aminokarboksilata/derivata, dok atomi azota ostaju nekoordinovani. Za sve komplekse predložen je kombinovani helatno-mostovni način vezivanja. Kompleksi su bili elektrohemijski stabilni u opsegu potencijala -1,0 do 1,0 V. Oni su preliminarno testirani na mikroorganizme zajedno sa ligandima, polaznim prostim solima i rastvaračima kao test supstancama. U nekim slučajevima je nađena izvesna antimikrobna aktivnost kompleksa.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives, Proučavanje novih kompleksa kobalta(II) sa oktaazamakrociklom i aminokarboksilatima ili njihovim derivatima",
volume = "74",
number = "6",
pages = "629-640",
doi = "10.2298/JSC0906629V"
}

Vučković, G., Tanasković, S., Antonijević-Nikolić, M., Živković-Radovanović, V.,& Gojgić-Cvijović, G.. (2009). A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 74(6), 629-640.
https://doi.org/10.2298/JSC0906629V

Vučković G, Tanasković S, Antonijević-Nikolić M, Živković-Radovanović V, Gojgić-Cvijović G. A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives. in Journal of the Serbian Chemical Society. 2009;74(6):629-640.
doi:10.2298/JSC0906629V .

Vučković, Gordana, Tanasković, Slađana, Antonijević-Nikolić, Mirjana, Živković-Radovanović, Vukosava, Gojgić-Cvijović, Gordana, "A study of novel cobalt(II) octaazamacrocyclic complexes with aminocarboxylates or their derivatives" in Journal of the Serbian Chemical Society, 74, no. 6 (2009):629-640,
https://doi.org/10.2298/JSC0906629V . .