@conference{
author = "Milenković, Milan and Erceg, Milica and Blagojević, Zorica and Đukić-Ćosić, Danijela and Antonijević, Biljana and Bulat, Zorica",
year = "2022",
abstract = "Phthalates are commonly used plasticizers for plastic materials. Number of toys are
made from plastic materials or are coated with plastic layer. No existence of chemical bound
between phthalates and polymer layers means their easy migration. Children’s exposure to
phthalates is recognised as a threat to their health, since phthalates interfere with hormones
level (endocrine disrupter chemicals – EDC), but can also induce hepatotoxicity, renal
toxicity, allergic diseases and astma and disrupt thyroid function. Rulebook on Toy safety
(“Official Gazette of RS” No. 78/2019) was published in 2019, to set rules on toys safety and
their free movement on the market. Phthalates are prohibited, individually or in combination
in a concentration equal to or greater than 0.1% (m/m). Butylbenzyl phthalate (BBP), Di-n-
butyl phthalate (DBP), Bis(2-ethylhexyl) phthalate (DEHP) and Diisobutyl phthalate (DIBP)
are listed as prohibited, but DIBP restrictions start from July 2023 (1). In accordance with
this legislative, laboratory of Institute of Public Health of Serbia “Dr Milan Jovanovic Batut”
analyses part of these toys present on the market in Serbia. Total of 232 toy samples were
analysed in the last 5 years (2017-2021), by HPLC-DAD. Phthalates are found in 40 samples
(17.2%), 10 samples (4.3%) were bellow and 30 (12.9%) exceeded concentration of 0.1%
(m/m). The most common elevated phthalates were DEHP and DBP. During 2019 and 2021
no phthalates are found in samples. Constant appearance of new toy manufacturers and
control of existing ones demand monitoring of toys present on RS market, for the purpose of
children's safety., Ftalati spadaju u najčešće korišćene plastifikatore za plastične materijale. Veliki broj
igračaka izrađen je od plastike ili je plastificiran. Usled nepostojanja hemijske veze između
ftalata i slojeva polimera, lako može doći do migracije ftalata. Izloženost dece ftalatima
prepoznata je kao pretnja po zdravlje, budući da su ftalati klasifikovani u grupu jedinjenja
endokrinih ometača (EDC), pošto utiču na promene nivoa hormona, ali takođe mogu dovesti i
do oštećenja jetre, bubrega, poremećaja rada štitaste žlezde, alergijskih bolesti i astme.
Pravilnik o bezbednosti igračaka Republike Srbije („Službeni glasnik RS” broj 78/2019)
donešen je u cilju uspostavljanja pravila o bezbednosti igračaka i njihovom slobodnom
kretanju na tržištu. Upotreba ftalata kao plastifikatora zabranjena je, pojedinačno ili u smeši,
ako je koncentracija jednaka ili veća od 0,1% (m/m). Na listi zabranjenih ftalata su:
butilbenzil ftalat (BBP), di-n-butil ftalat (DBP), di-2-etilheksil ftalat (DEHP), kao i di-izo-butil
ftalat (DIBP) čija zabrana stupa na snagu od jula 2023. godine (1). U skladu sa postojećim
propisima, laboratorija Instituta za javno zdravlje Srbije „Dr Milan Jovanović Batut“ analizira
deo igračaka prisutnih na tržištu u Srbiji. Tokom prethodnih 5 godina (2017-2021)
analizirano je ukupno 232 uzoraka igračaka. Ftalati su nađeni u 40 uzoraka (17,2%), od kojih
je 10 uzoraka (4,3%) imalo ispod, a 30 (12,9%) preko granične koncentracije od 0,1%
(m/m). Najčešće povišeni ftalati su DEHP i DBP. Tokom 2019. i 2021. godine u uzorcima nije
utvrđeno prisustvo ftalata. Usled stalne pojave novih proizvođača igračaka, kao i kontrole
već prisutnih, neophodan je redovan monitoring igračaka na tržištu RS radi bezbednosti
dece.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Presence of phthalates in toys analysed by Institute of Public helath “Dr Milan Jovanović Batutt” for a last five years period (2017-2021), Prisustvo ftalata u igračkama analiziranim u Institutu za javno zdravlje Srbije “Milan Jovanović Batut” za period od 5 godina (2017‐2021)",
volume = "72",
number = "4 suplement",
pages = "S563-S564",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4606"
}
