TY  - JOUR
AU  - Bajić, Vladan
AU  - Sudar-Milovanović, Emina
AU  - Potparević, Biljana
AU  - Živković, Lada
AU  - Miliccivc, Zorka
AU  - Stanimirović, Julijana
AU  - Bogdanović, Nikola
AU  - Isenović, Esma
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2591
AB  - Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder, and represents the most common form of dementia. The number of people affected by AD is estimated to be doubled by the year of 2050, and more than 100 million people worldwide will be affected by this disease. Still, there is no reliable diagnostic test which would indicate pre-symptomatic conditions or an increased risk of developing AD. The only drugs approved by the FDA belong to the cholinesterase inhibitors (ChEI) group, such as donepezil, rivastigmine, galantamine and memantine that belongs to a class of drugs named receptor NMDA antagonists. Most mainstream pharmacotherapeutic approaches act by slowing the progression of the condition rather than to treat or prevent the cause of AD. In this review we are presenting literature data from recent research related to new avenues in the classical approach to prevention and treatment of AD.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Current Pharmaceutical Analysis
T1  - Treatment of Alzheimer's Disease: Classical Therapeutic Approach
VL  - 12
IS  - 2
SP  - 82
EP  - 90
DO  - 10.2174/1573412911666150611184740
ER  - 

@article{
author = "Bajić, Vladan and Sudar-Milovanović, Emina and Potparević, Biljana and Živković, Lada and Miliccivc, Zorka and Stanimirović, Julijana and Bogdanović, Nikola and Isenović, Esma",
year = "2016",
abstract = "Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder, and represents the most common form of dementia. The number of people affected by AD is estimated to be doubled by the year of 2050, and more than 100 million people worldwide will be affected by this disease. Still, there is no reliable diagnostic test which would indicate pre-symptomatic conditions or an increased risk of developing AD. The only drugs approved by the FDA belong to the cholinesterase inhibitors (ChEI) group, such as donepezil, rivastigmine, galantamine and memantine that belongs to a class of drugs named receptor NMDA antagonists. Most mainstream pharmacotherapeutic approaches act by slowing the progression of the condition rather than to treat or prevent the cause of AD. In this review we are presenting literature data from recent research related to new avenues in the classical approach to prevention and treatment of AD.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Current Pharmaceutical Analysis",
title = "Treatment of Alzheimer's Disease: Classical Therapeutic Approach",
volume = "12",
number = "2",
pages = "82-90",
doi = "10.2174/1573412911666150611184740"
}

Bajić, V., Sudar-Milovanović, E., Potparević, B., Živković, L., Miliccivc, Z., Stanimirović, J., Bogdanović, N.,& Isenović, E.. (2016). Treatment of Alzheimer's Disease: Classical Therapeutic Approach. in Current Pharmaceutical Analysis
Bentham Science Publ Ltd, Sharjah., 12(2), 82-90.
https://doi.org/10.2174/1573412911666150611184740

Bajić V, Sudar-Milovanović E, Potparević B, Živković L, Miliccivc Z, Stanimirović J, Bogdanović N, Isenović E. Treatment of Alzheimer's Disease: Classical Therapeutic Approach. in Current Pharmaceutical Analysis. 2016;12(2):82-90.
doi:10.2174/1573412911666150611184740 .

Bajić, Vladan, Sudar-Milovanović, Emina, Potparević, Biljana, Živković, Lada, Miliccivc, Zorka, Stanimirović, Julijana, Bogdanović, Nikola, Isenović, Esma, "Treatment of Alzheimer's Disease: Classical Therapeutic Approach" in Current Pharmaceutical Analysis, 12, no. 2 (2016):82-90,
https://doi.org/10.2174/1573412911666150611184740 . .

TY  - JOUR
AU  - Unić-Stojanović, Dragana
AU  - Isenović, Esma
AU  - Jović, Miomir
AU  - Maravić-Stojković, Vera
AU  - Miljković, Milica
AU  - Gojković, Tamara
AU  - Milicić, Biljana
AU  - Bogdanović, Nikola
AU  - Radak, Đorđe
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2758
AB  - Copeptin is a sensitive and more stable surrogate marker for arginine vasopressin. In this study, we evaluated copeptin levels in carotid endarterectomy (CEA) patients, perioperatively, to determine whether copeptin levels can be related to carotid artery cross clamping (CC) time and to postoperative neurological outcomes. Copeptin, interleukin 6, C-reactive protein, cortisol, and brain natriuretic peptide were measured preoperatively (T1) and 3 hours postoperatively (T3) as well as intraoperatively (T2). We recruited 77 patients. Values of copeptin rose gradually over the observed times: T1 = 7.9 (6.4-9.6), T2 = 12.6 (9.3-16.8), and T3 = 72.3 (49.1-111.2) pmol/L. There was a significant difference for repeated measurement (P = .000, P = .000, and P = .000). Duration of carotid artery CC during CEA does not affect postoperative copeptin level (CC 13 minutes: 106.8 +/- 93.6 pmol/L, CC > 13 minutes: 96.7 +/- 89.1 pmol/L; P = .634). Preoperative copeptin level was significantly higher in patients with ulcerated plaque morphology. Activation of the stress axis in patients undergoing CEA results in copeptin elevation. Duration of CC during CEA does not affect postoperative copeptin levels.
PB  - Sage Publications Inc, Thousand Oaks
T2  - Angiology
T1  - Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia
VL  - 67
IS  - 10
SP  - 951
EP  - 960
DO  - 10.1177/0003319716629322
ER  - 

@article{
author = "Unić-Stojanović, Dragana and Isenović, Esma and Jović, Miomir and Maravić-Stojković, Vera and Miljković, Milica and Gojković, Tamara and Milicić, Biljana and Bogdanović, Nikola and Radak, Đorđe",
year = "2016",
abstract = "Copeptin is a sensitive and more stable surrogate marker for arginine vasopressin. In this study, we evaluated copeptin levels in carotid endarterectomy (CEA) patients, perioperatively, to determine whether copeptin levels can be related to carotid artery cross clamping (CC) time and to postoperative neurological outcomes. Copeptin, interleukin 6, C-reactive protein, cortisol, and brain natriuretic peptide were measured preoperatively (T1) and 3 hours postoperatively (T3) as well as intraoperatively (T2). We recruited 77 patients. Values of copeptin rose gradually over the observed times: T1 = 7.9 (6.4-9.6), T2 = 12.6 (9.3-16.8), and T3 = 72.3 (49.1-111.2) pmol/L. There was a significant difference for repeated measurement (P = .000, P = .000, and P = .000). Duration of carotid artery CC during CEA does not affect postoperative copeptin level (CC 13 minutes: 106.8 +/- 93.6 pmol/L, CC > 13 minutes: 96.7 +/- 89.1 pmol/L; P = .634). Preoperative copeptin level was significantly higher in patients with ulcerated plaque morphology. Activation of the stress axis in patients undergoing CEA results in copeptin elevation. Duration of CC during CEA does not affect postoperative copeptin levels.",
publisher = "Sage Publications Inc, Thousand Oaks",
journal = "Angiology",
title = "Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia",
volume = "67",
number = "10",
pages = "951-960",
doi = "10.1177/0003319716629322"
}

Unić-Stojanović, D., Isenović, E., Jović, M., Maravić-Stojković, V., Miljković, M., Gojković, T., Milicić, B., Bogdanović, N.,& Radak, Đ.. (2016). Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia. in Angiology
Sage Publications Inc, Thousand Oaks., 67(10), 951-960.
https://doi.org/10.1177/0003319716629322

Unić-Stojanović D, Isenović E, Jović M, Maravić-Stojković V, Miljković M, Gojković T, Milicić B, Bogdanović N, Radak Đ. Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia. in Angiology. 2016;67(10):951-960.
doi:10.1177/0003319716629322 .

Unić-Stojanović, Dragana, Isenović, Esma, Jović, Miomir, Maravić-Stojković, Vera, Miljković, Milica, Gojković, Tamara, Milicić, Biljana, Bogdanović, Nikola, Radak, Đorđe, "Copeptin Levels Do Not Correlate With Cross-Clamping Time in Patients Undergoing Carotid Endarterectomy Under General Anesthesia" in Angiology, 67, no. 10 (2016):951-960,
https://doi.org/10.1177/0003319716629322 . .