TY  - JOUR
AU  - Ivić, Branka
AU  - Ibrić, Svetlana
AU  - Cvetković, Nebojša
AU  - Petrović, Aleksandra
AU  - Trajković, Svetlana
AU  - Đurić, Zorica
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1401
AB  - The purpose of the study was to screen the effects of formulation factors on the in vitro release profile of diclofenac sodium from matrix tablets using design of experiment (DOE). Formulations of diclofenac sodium tablets, with Carbopol (R) 71G as matrix substance, were optimized by artificial neural network. According to Central Composite Design, 10 formulations of diclofenac sodium matrix tablets were prepared. As network inputs, concentration of Carbopol (R) 71G and the Kollidon (R) K-25 were selected. In vitro dissolution time profiles at 5 different sampling times were chosen as responses. The independent variables and the release parameters were processed by multilayer perceptrons neural network (MLP). Results of drug release studies indicate that drug release rates vary between different formulations, with a range of 1 h to more than 8 h to complete dissolution. For two tested formulations there was no difference between experimental and MLP predicted in vitro profiles. The M LP model was optimized. The root mean square value for the trained network was 0.07%, which indicated that the optimal MLP model was reached. The optimal tablet formulation predicted by MLP was with 23% of Carbopol (R) 710 and 0.8% of Kollidon (R) K-25. Calculated difference factor (f(1) 7.37) and similarity factor (f(2) 70.79) indicate that there is no difference between predicted and experimentally observed drug release profiles for the optimal formulation. The satisfactory prediction of drug release for optimal formulation by the MLP in this study has shown the applicability of this optimization method in modeling extended release tablet formulation.
PB  - Pharmaceutical Soc Japan, Tokyo
T2  - Chemical & Pharmaceutical Bulletin
T1  - Application of Design of Experiments and Multilayer Perceptrons Neural Network in the Optimization of Diclofenac Sodium Extended Release Tablets with Carbopol (R) 71G
VL  - 58
IS  - 7
SP  - 947
EP  - 949
DO  - 10.1248/cpb.58.947
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1401
ER  - 

@article{
author = "Ivić, Branka and Ibrić, Svetlana and Cvetković, Nebojša and Petrović, Aleksandra and Trajković, Svetlana and Đurić, Zorica",
year = "2010",
abstract = "The purpose of the study was to screen the effects of formulation factors on the in vitro release profile of diclofenac sodium from matrix tablets using design of experiment (DOE). Formulations of diclofenac sodium tablets, with Carbopol (R) 71G as matrix substance, were optimized by artificial neural network. According to Central Composite Design, 10 formulations of diclofenac sodium matrix tablets were prepared. As network inputs, concentration of Carbopol (R) 71G and the Kollidon (R) K-25 were selected. In vitro dissolution time profiles at 5 different sampling times were chosen as responses. The independent variables and the release parameters were processed by multilayer perceptrons neural network (MLP). Results of drug release studies indicate that drug release rates vary between different formulations, with a range of 1 h to more than 8 h to complete dissolution. For two tested formulations there was no difference between experimental and MLP predicted in vitro profiles. The M LP model was optimized. The root mean square value for the trained network was 0.07%, which indicated that the optimal MLP model was reached. The optimal tablet formulation predicted by MLP was with 23% of Carbopol (R) 710 and 0.8% of Kollidon (R) K-25. Calculated difference factor (f(1) 7.37) and similarity factor (f(2) 70.79) indicate that there is no difference between predicted and experimentally observed drug release profiles for the optimal formulation. The satisfactory prediction of drug release for optimal formulation by the MLP in this study has shown the applicability of this optimization method in modeling extended release tablet formulation.",
publisher = "Pharmaceutical Soc Japan, Tokyo",
journal = "Chemical & Pharmaceutical Bulletin",
title = "Application of Design of Experiments and Multilayer Perceptrons Neural Network in the Optimization of Diclofenac Sodium Extended Release Tablets with Carbopol (R) 71G",
volume = "58",
number = "7",
pages = "947-949",
doi = "10.1248/cpb.58.947",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1401"
}

Ivić, B., Ibrić, S., Cvetković, N., Petrović, A., Trajković, S.,& Đurić, Z.. (2010). Application of Design of Experiments and Multilayer Perceptrons Neural Network in the Optimization of Diclofenac Sodium Extended Release Tablets with Carbopol (R) 71G. in Chemical & Pharmaceutical Bulletin
Pharmaceutical Soc Japan, Tokyo., 58(7), 947-949.
https://doi.org/10.1248/cpb.58.947
https://hdl.handle.net/21.15107/rcub_farfar_1401

Ivić B, Ibrić S, Cvetković N, Petrović A, Trajković S, Đurić Z. Application of Design of Experiments and Multilayer Perceptrons Neural Network in the Optimization of Diclofenac Sodium Extended Release Tablets with Carbopol (R) 71G. in Chemical & Pharmaceutical Bulletin. 2010;58(7):947-949.
doi:10.1248/cpb.58.947
https://hdl.handle.net/21.15107/rcub_farfar_1401 .

Ivić, Branka, Ibrić, Svetlana, Cvetković, Nebojša, Petrović, Aleksandra, Trajković, Svetlana, Đurić, Zorica, "Application of Design of Experiments and Multilayer Perceptrons Neural Network in the Optimization of Diclofenac Sodium Extended Release Tablets with Carbopol (R) 71G" in Chemical & Pharmaceutical Bulletin, 58, no. 7 (2010):947-949,
https://doi.org/10.1248/cpb.58.947 .,
https://hdl.handle.net/21.15107/rcub_farfar_1401 .

TY  - JOUR
AU  - Mašić, Ivana
AU  - Ilić, Marija
AU  - Petrović, Ljiljana
AU  - Trajković, Svetlana
AU  - Homšek, Irena
AU  - Parojčić, Jelena
AU  - Đurić, Zorica
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1316
AB  - With the introduction of Biopharmaceutics Classification System (BCS) and 'biowaiver' concept, there is an increased interest in the extension of biowaiver criteria to highly soluble/low permeable drugs (i.e. BCS class 3 drugs). In order to justify the exemption from in vivo studies, a discriminating in vitro dissolution method should be established. The aim of this study was to evaluate the effects of the type of apparatus, agitation intensity and pH value on metformin hydrochloride release from commercially available immediate release tablets. The tablets were also assayed for their disintegration time. The results obtained revealed that the drug release rate was considerably influenced by the agitation intensity. The fastest dissolution rates were observed in the basket apparatus while the slowest drug release from all the investigated products was obtained in the mini paddle apparatus. Significant differences were observed between the dissolution profiles of the investigated products nevertheless of the experimental conditions applied. The results obtained showed that there is a connection between tablet disintegration times and dissolution rates. The results obtained indicate that current similarity factor criteria might be too conservative, as well as the recommended request for very rapid dissolution in the biowaiver application for highly soluble drugs and merits further consideration.
AB  - Prihvatanje Biofarmaceutskog sistema klasifikacije (BSK) i 'biowaiver' koncepta od strane regulatornih agencija, doveo je do povećanog interesa za mogućnost njihove primene u slučaju visoko rastvorljivih/nisko permeabilnih lekova (koji pripadaju BSK grupi 3). Da bi se opravdao zahtev za izostavljanje in vivo ispitivanja, potrebno je razviti diskriminatoran metod za in vitro ispitivanje brzine rastvaranja. Cilj ovog rada bio je da se ispita uticaj vrste aparature, intenziteta mešanja i pH vrednosti medijuma na brzinu rastvaranja metformin-hidrohlorida iz tableta različitih proizvođača. Takođe je ispitana i raspadljivost tableta. Rezultati ispitivanja su pokazali da intenzitet mešanja u znatnoj meri utiče na brzinu rastvaranja metformin-hidrohlorida iz tableta. Najbrže rastvaranje postignuto je u aparaturi sa korpicom, pri 100 rpm, dok je rastvaranje metformin-hidrohlorida bilo najsporije u aparaturi tipa mini lopatice, pri 50 rpm. Uočene su značajne razlike između ispitivanih preparata bez obzira na primenjene eksperimentalne uslove. Rezultati ispitivanja brzine rastvaranja bili su u korelaciji sa raspadljivošću tableta. Dobijeni rezultati ukazuju da je postojeći kriterijum prihvatljivosti za vrednost faktora sličnosti pri uporednom ispitivanju brzine rastvaranja, kao i zahtev za 'veoma brzo rastvaranje' s ciljem izostavljanja in vivo ispitivanja u slučaju visoko rastvorljivih lekovitih supstanci veoma strog i zaslužuje da bude dodatno razmotren.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Comparative dissolution study of commercially available metformin hydrochloride immediate-release tablets
T1  - Uporedno ispitivanje brzine rastvaranja metformin-hidrohlorida iz tableta različitih proizvođača
VL  - 59
IS  - 4
SP  - 279
EP  - 293
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1316
ER  - 

@article{
author = "Mašić, Ivana and Ilić, Marija and Petrović, Ljiljana and Trajković, Svetlana and Homšek, Irena and Parojčić, Jelena and Đurić, Zorica",
year = "2009",
abstract = "With the introduction of Biopharmaceutics Classification System (BCS) and 'biowaiver' concept, there is an increased interest in the extension of biowaiver criteria to highly soluble/low permeable drugs (i.e. BCS class 3 drugs). In order to justify the exemption from in vivo studies, a discriminating in vitro dissolution method should be established. The aim of this study was to evaluate the effects of the type of apparatus, agitation intensity and pH value on metformin hydrochloride release from commercially available immediate release tablets. The tablets were also assayed for their disintegration time. The results obtained revealed that the drug release rate was considerably influenced by the agitation intensity. The fastest dissolution rates were observed in the basket apparatus while the slowest drug release from all the investigated products was obtained in the mini paddle apparatus. Significant differences were observed between the dissolution profiles of the investigated products nevertheless of the experimental conditions applied. The results obtained showed that there is a connection between tablet disintegration times and dissolution rates. The results obtained indicate that current similarity factor criteria might be too conservative, as well as the recommended request for very rapid dissolution in the biowaiver application for highly soluble drugs and merits further consideration., Prihvatanje Biofarmaceutskog sistema klasifikacije (BSK) i 'biowaiver' koncepta od strane regulatornih agencija, doveo je do povećanog interesa za mogućnost njihove primene u slučaju visoko rastvorljivih/nisko permeabilnih lekova (koji pripadaju BSK grupi 3). Da bi se opravdao zahtev za izostavljanje in vivo ispitivanja, potrebno je razviti diskriminatoran metod za in vitro ispitivanje brzine rastvaranja. Cilj ovog rada bio je da se ispita uticaj vrste aparature, intenziteta mešanja i pH vrednosti medijuma na brzinu rastvaranja metformin-hidrohlorida iz tableta različitih proizvođača. Takođe je ispitana i raspadljivost tableta. Rezultati ispitivanja su pokazali da intenzitet mešanja u znatnoj meri utiče na brzinu rastvaranja metformin-hidrohlorida iz tableta. Najbrže rastvaranje postignuto je u aparaturi sa korpicom, pri 100 rpm, dok je rastvaranje metformin-hidrohlorida bilo najsporije u aparaturi tipa mini lopatice, pri 50 rpm. Uočene su značajne razlike između ispitivanih preparata bez obzira na primenjene eksperimentalne uslove. Rezultati ispitivanja brzine rastvaranja bili su u korelaciji sa raspadljivošću tableta. Dobijeni rezultati ukazuju da je postojeći kriterijum prihvatljivosti za vrednost faktora sličnosti pri uporednom ispitivanju brzine rastvaranja, kao i zahtev za 'veoma brzo rastvaranje' s ciljem izostavljanja in vivo ispitivanja u slučaju visoko rastvorljivih lekovitih supstanci veoma strog i zaslužuje da bude dodatno razmotren.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Comparative dissolution study of commercially available metformin hydrochloride immediate-release tablets, Uporedno ispitivanje brzine rastvaranja metformin-hidrohlorida iz tableta različitih proizvođača",
volume = "59",
number = "4",
pages = "279-293",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1316"
}

Mašić, I., Ilić, M., Petrović, L., Trajković, S., Homšek, I., Parojčić, J.,& Đurić, Z.. (2009). Comparative dissolution study of commercially available metformin hydrochloride immediate-release tablets. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 59(4), 279-293.
https://hdl.handle.net/21.15107/rcub_farfar_1316

Mašić I, Ilić M, Petrović L, Trajković S, Homšek I, Parojčić J, Đurić Z. Comparative dissolution study of commercially available metformin hydrochloride immediate-release tablets. in Arhiv za farmaciju. 2009;59(4):279-293.
https://hdl.handle.net/21.15107/rcub_farfar_1316 .

Mašić, Ivana, Ilić, Marija, Petrović, Ljiljana, Trajković, Svetlana, Homšek, Irena, Parojčić, Jelena, Đurić, Zorica, "Comparative dissolution study of commercially available metformin hydrochloride immediate-release tablets" in Arhiv za farmaciju, 59, no. 4 (2009):279-293,
https://hdl.handle.net/21.15107/rcub_farfar_1316 .

TY  - JOUR
AU  - Petrović, Aleksandra
AU  - Ibrić, Svetlana
AU  - Trajković, Svetlana
AU  - Popović, Radmila
AU  - Đurić, Zorica
AU  - Popadić, Dragica
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1284
AB  - The purpose of this study was to investigate the effect of various in vitro test conditions, on the release properties of theophylline (TP) from aminophylline (AP) matrices based on different hydroxypropylmethylcellulose (HPMC) ratio and viscosity grades. The General full factorial experimental design 3 x 3 x 3 was used, based on three independent variables: applied in vitro test (X1), HPMC/drug ratio (X2) and polymer viscosity grade (X3). The drug release percent at 2h (Y-2h), 4h (Y-4h) and 8 h (Y-8h) and time for 50% of TP release from matrices (Y-T50%) were response variables. Three in vitro tests were used: Test 1 and Test 4 (Theophylline Extended-release Capsules, USP 30) and Half-change method. According to factorial design analyses, in vitro test was the most significant factor influencing mechanism and amount of drug release. For Half Change method erosion was the predominant mechanism indicating Case - II transport, while for Test 1 the release mechanism were followed by both diffusion and erosion. The lowest release exponent n values, obtained from Ritger-Pepass equation, for Test 4 indicate diffusion process inclining from Fickian diffusion to Anomalous transport. Therefore, it is in the stage of development, useful to consider the influence of various in vitro test conditions on the formulation, in order to choose an optimal test for the purpose of future drug release examination.
PB  - Pharmaceutical Soc Korea, Seoul
T2  - Archives of Pharmacal Research
T1  - An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design
VL  - 32
IS  - 7
SP  - 1087
EP  - 1096
DO  - 10.1007/s12272-009-1715-y
ER  - 

@article{
author = "Petrović, Aleksandra and Ibrić, Svetlana and Trajković, Svetlana and Popović, Radmila and Đurić, Zorica and Popadić, Dragica",
year = "2009",
abstract = "The purpose of this study was to investigate the effect of various in vitro test conditions, on the release properties of theophylline (TP) from aminophylline (AP) matrices based on different hydroxypropylmethylcellulose (HPMC) ratio and viscosity grades. The General full factorial experimental design 3 x 3 x 3 was used, based on three independent variables: applied in vitro test (X1), HPMC/drug ratio (X2) and polymer viscosity grade (X3). The drug release percent at 2h (Y-2h), 4h (Y-4h) and 8 h (Y-8h) and time for 50% of TP release from matrices (Y-T50%) were response variables. Three in vitro tests were used: Test 1 and Test 4 (Theophylline Extended-release Capsules, USP 30) and Half-change method. According to factorial design analyses, in vitro test was the most significant factor influencing mechanism and amount of drug release. For Half Change method erosion was the predominant mechanism indicating Case - II transport, while for Test 1 the release mechanism were followed by both diffusion and erosion. The lowest release exponent n values, obtained from Ritger-Pepass equation, for Test 4 indicate diffusion process inclining from Fickian diffusion to Anomalous transport. Therefore, it is in the stage of development, useful to consider the influence of various in vitro test conditions on the formulation, in order to choose an optimal test for the purpose of future drug release examination.",
publisher = "Pharmaceutical Soc Korea, Seoul",
journal = "Archives of Pharmacal Research",
title = "An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design",
volume = "32",
number = "7",
pages = "1087-1096",
doi = "10.1007/s12272-009-1715-y"
}

Petrović, A., Ibrić, S., Trajković, S., Popović, R., Đurić, Z.,& Popadić, D.. (2009). An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design. in Archives of Pharmacal Research
Pharmaceutical Soc Korea, Seoul., 32(7), 1087-1096.
https://doi.org/10.1007/s12272-009-1715-y

Petrović A, Ibrić S, Trajković S, Popović R, Đurić Z, Popadić D. An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design. in Archives of Pharmacal Research. 2009;32(7):1087-1096.
doi:10.1007/s12272-009-1715-y .

Petrović, Aleksandra, Ibrić, Svetlana, Trajković, Svetlana, Popović, Radmila, Đurić, Zorica, Popadić, Dragica, "An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design" in Archives of Pharmacal Research, 32, no. 7 (2009):1087-1096,
https://doi.org/10.1007/s12272-009-1715-y . .

TY  - JOUR
AU  - Petrović, Aleksandra
AU  - Cvetković, Nebojša
AU  - Ibrić, Svetlana
AU  - Trajković, Svetlana
AU  - Đurić, Zorica
AU  - Popadić, Dragica
AU  - Popović, Radmila
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1191
AB  - Using mixture experimental design, the effect of carbomer (Carbopole (R) 971P NF) and hydroxypropylmethylcellulose (Methocel (R) K100M or Methocel (R) K4M) combination on the release profile and on the mechanism of drug liberation from matrix tablet was investigated. The numerical optimization procedure was also applied to establish and obtain formulation with desired drug release. The amount of TP released, release rate and mechanism varied with carbomer ratio in total matrix and HPMC viscosity. Increasing carbomer fractions led to a decrease in drug release. Anomalous diffusion was found in all matrices containing carbomer, while Case - II transport was predominant for tablet based on HPMC only. The predicted and obtained profiles for optimized formulations showed similarity. Those results indicate that Simplex Lattice Mixture experimental design and numerical optimization procedure can be applied during development to obtain sustained release matrix formulation with desired release profile.
PB  - Pharmaceutical Soc Korea, Seoul
T2  - Archives of Pharmacal Research
T1  - Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose
VL  - 32
IS  - 12
SP  - 1767
EP  - 1774
DO  - 10.1007/s12272-009-2215-9
ER  - 

@article{
author = "Petrović, Aleksandra and Cvetković, Nebojša and Ibrić, Svetlana and Trajković, Svetlana and Đurić, Zorica and Popadić, Dragica and Popović, Radmila",
year = "2009",
abstract = "Using mixture experimental design, the effect of carbomer (Carbopole (R) 971P NF) and hydroxypropylmethylcellulose (Methocel (R) K100M or Methocel (R) K4M) combination on the release profile and on the mechanism of drug liberation from matrix tablet was investigated. The numerical optimization procedure was also applied to establish and obtain formulation with desired drug release. The amount of TP released, release rate and mechanism varied with carbomer ratio in total matrix and HPMC viscosity. Increasing carbomer fractions led to a decrease in drug release. Anomalous diffusion was found in all matrices containing carbomer, while Case - II transport was predominant for tablet based on HPMC only. The predicted and obtained profiles for optimized formulations showed similarity. Those results indicate that Simplex Lattice Mixture experimental design and numerical optimization procedure can be applied during development to obtain sustained release matrix formulation with desired release profile.",
publisher = "Pharmaceutical Soc Korea, Seoul",
journal = "Archives of Pharmacal Research",
title = "Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose",
volume = "32",
number = "12",
pages = "1767-1774",
doi = "10.1007/s12272-009-2215-9"
}

Petrović, A., Cvetković, N., Ibrić, S., Trajković, S., Đurić, Z., Popadić, D.,& Popović, R.. (2009). Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose. in Archives of Pharmacal Research
Pharmaceutical Soc Korea, Seoul., 32(12), 1767-1774.
https://doi.org/10.1007/s12272-009-2215-9

Petrović A, Cvetković N, Ibrić S, Trajković S, Đurić Z, Popadić D, Popović R. Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose. in Archives of Pharmacal Research. 2009;32(12):1767-1774.
doi:10.1007/s12272-009-2215-9 .

Petrović, Aleksandra, Cvetković, Nebojša, Ibrić, Svetlana, Trajković, Svetlana, Đurić, Zorica, Popadić, Dragica, Popović, Radmila, "Application of Mixture Experimental Design in the Formulation and Optimization of Matrix Tablets Containing Carbomer and Hydroxypropylmethylcellulose" in Archives of Pharmacal Research, 32, no. 12 (2009):1767-1774,
https://doi.org/10.1007/s12272-009-2215-9 . .

TY  - CONF
AU  - Ivić, Branka
AU  - Cvetković, Nebojša
AU  - Ibrić, Svetlana
AU  - Petrović, Aleksandra
AU  - Trajković, Svetlana
AU  - Đurić, Zorica
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/796
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - The influence of different factors on diclofenac sodium release from extended release matrices
T1  - Uticaj različitih faktora na oslobađanje diklofenak natrijuma iz matriks tableta sa produženim oslobađanjem
VL  - 56
IS  - 4
SP  - 474
EP  - 475
UR  - https://hdl.handle.net/21.15107/rcub_farfar_796
ER  - 

@conference{
author = "Ivić, Branka and Cvetković, Nebojša and Ibrić, Svetlana and Petrović, Aleksandra and Trajković, Svetlana and Đurić, Zorica",
year = "2006",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "The influence of different factors on diclofenac sodium release from extended release matrices, Uticaj različitih faktora na oslobađanje diklofenak natrijuma iz matriks tableta sa produženim oslobađanjem",
volume = "56",
number = "4",
pages = "474-475",
url = "https://hdl.handle.net/21.15107/rcub_farfar_796"
}

Ivić, B., Cvetković, N., Ibrić, S., Petrović, A., Trajković, S.,& Đurić, Z.. (2006). The influence of different factors on diclofenac sodium release from extended release matrices. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 56(4), 474-475.
https://hdl.handle.net/21.15107/rcub_farfar_796

Ivić B, Cvetković N, Ibrić S, Petrović A, Trajković S, Đurić Z. The influence of different factors on diclofenac sodium release from extended release matrices. in Arhiv za farmaciju. 2006;56(4):474-475.
https://hdl.handle.net/21.15107/rcub_farfar_796 .

Ivić, Branka, Cvetković, Nebojša, Ibrić, Svetlana, Petrović, Aleksandra, Trajković, Svetlana, Đurić, Zorica, "The influence of different factors on diclofenac sodium release from extended release matrices" in Arhiv za farmaciju, 56, no. 4 (2006):474-475,
https://hdl.handle.net/21.15107/rcub_farfar_796 .

TY  - CONF
AU  - Petrović, Aleksandra
AU  - Raić, M.
AU  - Trajković, Svetlana
AU  - Ibrić, Svetlana
AU  - Popović, R.
AU  - Popadić, Dragica
AU  - Đurić, Zorica
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/787
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - Effect of film coating and storage conditions on tablets quality with moisture sensitive drug
T1  - Uticaj film obloge i uslova čuvanja na kvalitet tableta sa aktivnom supstancom osetljivom na vlagu
VL  - 56
IS  - 4
SP  - 458
EP  - 459
UR  - https://hdl.handle.net/21.15107/rcub_farfar_787
ER  - 

@conference{
author = "Petrović, Aleksandra and Raić, M. and Trajković, Svetlana and Ibrić, Svetlana and Popović, R. and Popadić, Dragica and Đurić, Zorica",
year = "2006",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Effect of film coating and storage conditions on tablets quality with moisture sensitive drug, Uticaj film obloge i uslova čuvanja na kvalitet tableta sa aktivnom supstancom osetljivom na vlagu",
volume = "56",
number = "4",
pages = "458-459",
url = "https://hdl.handle.net/21.15107/rcub_farfar_787"
}

Petrović, A., Raić, M., Trajković, S., Ibrić, S., Popović, R., Popadić, D.,& Đurić, Z.. (2006). Effect of film coating and storage conditions on tablets quality with moisture sensitive drug. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 56(4), 458-459.
https://hdl.handle.net/21.15107/rcub_farfar_787

Petrović A, Raić M, Trajković S, Ibrić S, Popović R, Popadić D, Đurić Z. Effect of film coating and storage conditions on tablets quality with moisture sensitive drug. in Arhiv za farmaciju. 2006;56(4):458-459.
https://hdl.handle.net/21.15107/rcub_farfar_787 .

Petrović, Aleksandra, Raić, M., Trajković, Svetlana, Ibrić, Svetlana, Popović, R., Popadić, Dragica, Đurić, Zorica, "Effect of film coating and storage conditions on tablets quality with moisture sensitive drug" in Arhiv za farmaciju, 56, no. 4 (2006):458-459,
https://hdl.handle.net/21.15107/rcub_farfar_787 .

TY  - CONF
AU  - Petrović, Aleksandra
AU  - Cvetković, Nebojša
AU  - Ibrić, Svetlana
AU  - Trajković, Svetlana
AU  - Popadić, Dragica
AU  - Đurić, Zorica
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/788
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - Evaluation of drug release from matrix tablets containing carbomer and HPMC using experimental design
T1  - Ispitivanje oslobađanja leka iz matriks tableta na bazi karbomer-a i HPMC-a primenom eksperimentalnog dizajna
VL  - 56
IS  - 4
SP  - 460
EP  - 461
UR  - https://hdl.handle.net/21.15107/rcub_farfar_788
ER  - 

@conference{
author = "Petrović, Aleksandra and Cvetković, Nebojša and Ibrić, Svetlana and Trajković, Svetlana and Popadić, Dragica and Đurić, Zorica",
year = "2006",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Evaluation of drug release from matrix tablets containing carbomer and HPMC using experimental design, Ispitivanje oslobađanja leka iz matriks tableta na bazi karbomer-a i HPMC-a primenom eksperimentalnog dizajna",
volume = "56",
number = "4",
pages = "460-461",
url = "https://hdl.handle.net/21.15107/rcub_farfar_788"
}

Petrović, A., Cvetković, N., Ibrić, S., Trajković, S., Popadić, D.,& Đurić, Z.. (2006). Evaluation of drug release from matrix tablets containing carbomer and HPMC using experimental design. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 56(4), 460-461.
https://hdl.handle.net/21.15107/rcub_farfar_788

Petrović A, Cvetković N, Ibrić S, Trajković S, Popadić D, Đurić Z. Evaluation of drug release from matrix tablets containing carbomer and HPMC using experimental design. in Arhiv za farmaciju. 2006;56(4):460-461.
https://hdl.handle.net/21.15107/rcub_farfar_788 .

Petrović, Aleksandra, Cvetković, Nebojša, Ibrić, Svetlana, Trajković, Svetlana, Popadić, Dragica, Đurić, Zorica, "Evaluation of drug release from matrix tablets containing carbomer and HPMC using experimental design" in Arhiv za farmaciju, 56, no. 4 (2006):460-461,
https://hdl.handle.net/21.15107/rcub_farfar_788 .

TY  - CONF
AU  - Petrović, Aleksandra
AU  - Cvetković, Nebojša
AU  - Trajković, Svetlana
AU  - Ibrić, Svetlana
AU  - Popadić, Dragica
AU  - Đurić, Zorica
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/792
PB  - Elsevier Science BV, Amsterdam
C3  - Journal of Controlled Release
T1  - Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC
VL  - 116
IS  - 2
DO  - 10.1016/j.jconrel.2006.09.073
ER  - 

@conference{
author = "Petrović, Aleksandra and Cvetković, Nebojša and Trajković, Svetlana and Ibrić, Svetlana and Popadić, Dragica and Đurić, Zorica",
year = "2006",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Controlled Release",
title = "Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC",
volume = "116",
number = "2",
doi = "10.1016/j.jconrel.2006.09.073"
}

Petrović, A., Cvetković, N., Trajković, S., Ibrić, S., Popadić, D.,& Đurić, Z.. (2006). Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC. in Journal of Controlled Release
Elsevier Science BV, Amsterdam., 116(2).
https://doi.org/10.1016/j.jconrel.2006.09.073

Petrović A, Cvetković N, Trajković S, Ibrić S, Popadić D, Đurić Z. Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC. in Journal of Controlled Release. 2006;116(2).
doi:10.1016/j.jconrel.2006.09.073 .

Petrović, Aleksandra, Cvetković, Nebojša, Trajković, Svetlana, Ibrić, Svetlana, Popadić, Dragica, Đurić, Zorica, "Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC" in Journal of Controlled Release, 116, no. 2 (2006),
https://doi.org/10.1016/j.jconrel.2006.09.073 . .