TY  - CONF
AU  - Tadić, Ivana
AU  - Vujasinović-Stupar, Nada
AU  - Tasić, Ljiljana
AU  - Stevanović, Dejan
AU  - Dimić, A.
AU  - Stamenković, Bojana
AU  - Stojanović, S.
AU  - Milenković, S.
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1985
AB  - OBJECTIVES: International Osteoporosis Foundation Quality of Life questionnaire
(QUALEFFO-41) is the specific questionnaire for the postmenopausal women
with osteoporosis and vertebral fractures. Reliability of the questionnaire could
be confirmed by sensitivity and specificity. The objective of this stidy is to test
the sensitivity and specificity of the QUALEFFO-41 questionnaire. METHODS: A
case-control study was conducted during the period of June 2010 - October 2011
to test the main characteristics of the questionnaire. The study included 100
patients with osteoporosis (50 cases with vertebral fractures and 50 controls
without fractures). The questionnaire EQ-5D (with direct-scoring) was used for
comparison of the results with the QUALEFFO-41 (with reverse-scoring). The
study was performed in two medical centers in Serbia. RESULTS: The results of
the ROC curve analysis (between the case and control group of patients)
indicated that the AUC ranges for all five dimensions of the QUALEFFO-41
questionnaire and the total score were 0.62–0.69. The QUALEFFO-41 had a better
prediction of the value of HRQOL of cases compared to the generic questionnaire
EQ-5D (the AUC difference of the total scores was 0.099, p=0.013). Correlations
between the total scores of the QUALEFFO-41 and the EQ-5D health state value,
for both groups, were negative and statistically significant (r=-0.78, p<0.001 and r
= -0.73, p<0.001, respectively). CONCLUSIONS: The QUALEFFO-41 has the ability
to detect the patients with osteoporosis and vertebral fractures among the
osteoporosis patients. This questionnaire is more specific for the osteoporosis
patients with fractures in relation to the EQ-5D questionnaire.
PB  - Elsevier Inc.
C3  - Value in Health
T1  - Sensitivity and specificity of a quality of life questionnaire qualeffo-41
VL  - 16
IS  - 3
SP  - A228
EP  - A228
DO  - 10.1016/j.jval.2013.03.1156
ER  - 

@conference{
author = "Tadić, Ivana and Vujasinović-Stupar, Nada and Tasić, Ljiljana and Stevanović, Dejan and Dimić, A. and Stamenković, Bojana and Stojanović, S. and Milenković, S.",
year = "2013",
abstract = "OBJECTIVES: International Osteoporosis Foundation Quality of Life questionnaire
(QUALEFFO-41) is the specific questionnaire for the postmenopausal women
with osteoporosis and vertebral fractures. Reliability of the questionnaire could
be confirmed by sensitivity and specificity. The objective of this stidy is to test
the sensitivity and specificity of the QUALEFFO-41 questionnaire. METHODS: A
case-control study was conducted during the period of June 2010 - October 2011
to test the main characteristics of the questionnaire. The study included 100
patients with osteoporosis (50 cases with vertebral fractures and 50 controls
without fractures). The questionnaire EQ-5D (with direct-scoring) was used for
comparison of the results with the QUALEFFO-41 (with reverse-scoring). The
study was performed in two medical centers in Serbia. RESULTS: The results of
the ROC curve analysis (between the case and control group of patients)
indicated that the AUC ranges for all five dimensions of the QUALEFFO-41
questionnaire and the total score were 0.62–0.69. The QUALEFFO-41 had a better
prediction of the value of HRQOL of cases compared to the generic questionnaire
EQ-5D (the AUC difference of the total scores was 0.099, p=0.013). Correlations
between the total scores of the QUALEFFO-41 and the EQ-5D health state value,
for both groups, were negative and statistically significant (r=-0.78, p<0.001 and r
= -0.73, p<0.001, respectively). CONCLUSIONS: The QUALEFFO-41 has the ability
to detect the patients with osteoporosis and vertebral fractures among the
osteoporosis patients. This questionnaire is more specific for the osteoporosis
patients with fractures in relation to the EQ-5D questionnaire.",
publisher = "Elsevier Inc.",
journal = "Value in Health",
title = "Sensitivity and specificity of a quality of life questionnaire qualeffo-41",
volume = "16",
number = "3",
pages = "A228-A228",
doi = "10.1016/j.jval.2013.03.1156"
}

Tadić, I., Vujasinović-Stupar, N., Tasić, L., Stevanović, D., Dimić, A., Stamenković, B., Stojanović, S.,& Milenković, S.. (2013). Sensitivity and specificity of a quality of life questionnaire qualeffo-41. in Value in Health
Elsevier Inc.., 16(3), A228-A228.
https://doi.org/10.1016/j.jval.2013.03.1156

Tadić I, Vujasinović-Stupar N, Tasić L, Stevanović D, Dimić A, Stamenković B, Stojanović S, Milenković S. Sensitivity and specificity of a quality of life questionnaire qualeffo-41. in Value in Health. 2013;16(3):A228-A228.
doi:10.1016/j.jval.2013.03.1156 .

Tadić, Ivana, Vujasinović-Stupar, Nada, Tasić, Ljiljana, Stevanović, Dejan, Dimić, A., Stamenković, Bojana, Stojanović, S., Milenković, S., "Sensitivity and specificity of a quality of life questionnaire qualeffo-41" in Value in Health, 16, no. 3 (2013):A228-A228,
https://doi.org/10.1016/j.jval.2013.03.1156 . .

TY  - JOUR
AU  - Tadić, Ivana
AU  - Vujasinović-Stupar, Nada
AU  - Tasić, Ljiljana
AU  - Stevanović, Dejan
AU  - Dimić, Aleksandar
AU  - Stamenković, Bojana
AU  - Stojanović, Sonja
AU  - Milenković, Sasa
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1622
AB  - Background: Vertebral fractures could lead to reduced physical, social and mental functioning, and loss of personal independence. Therefore, during the treatment of osteoporosis, it has become necessary to examine the changes in everyday functioning, well-being and health related quality of life (HRQOL). To that effect, this study aims to translate, culturally adapt, and validate the Serbian version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) for patients with vertebral fractures. Methods: Nine female patients with osteoporosis participated in the pre-validation study. A validation, case-control study included two groups of female patients: one that consisted of 50 female patients with osteoporosis, and with at least one vertebral fracture, and another one that consisted of 50 control patients with osteoporosis but without fractures. They completed the QUALEFFO-41 and the EuroQol group questionnaire with five dimensions (EQ-5D) twice within a month. The validation study examined internal consistency, concurrent validity, test-retest reliability, sensitivity and specificity. Results: During the pre-validation study, three of the items in the QUALEFFO-41 were slightly changed. Afterwards, during the validation study, the statistically significant differences (adjusted for: age, duration of menopause, current employment and marital status) in the mean values of all domains and total scores between the groups were noted. For the case group, the internal consistency of the QUALEFFO-41 domains and of total questionnaire was above 0.70. The test-retest reliability was tested by the intraclass correlation coefficients (ICC) that were in range 0.87 - 0.96 for the case, and 0.15 - 0.83 for the control group. Correlations between the total scores of the QUALEFFO-41 and the EQ-5D health state value, for both groups were negative and statistically significant (r = -0.78, p lt 0.001 and r = -0.73, p lt 0.001, respectively). The QUALEFFO-41 had a better prediction of the value of HRQOL of cases compared to the generic questionnaire EQ-5D (the AUC difference was 0.099, p = 0.013). Conclusions: The Serbian QUALEFFO-41 version is reliable, valid, sensitive and predictive for examinations of HRQOL in patients with prevalent vertebral fractures and can be used in further studies.
PB  - Biomed Central Ltd, London
T2  - Health and Quality of Life Outcomes
T1  - Validation of the osteoporosis quality of life questionnaire QUALEFFO-41 for the Serbian population
VL  - 10
DO  - 10.1186/1477-7525-10-74
ER  - 

@article{
author = "Tadić, Ivana and Vujasinović-Stupar, Nada and Tasić, Ljiljana and Stevanović, Dejan and Dimić, Aleksandar and Stamenković, Bojana and Stojanović, Sonja and Milenković, Sasa",
year = "2012",
abstract = "Background: Vertebral fractures could lead to reduced physical, social and mental functioning, and loss of personal independence. Therefore, during the treatment of osteoporosis, it has become necessary to examine the changes in everyday functioning, well-being and health related quality of life (HRQOL). To that effect, this study aims to translate, culturally adapt, and validate the Serbian version of Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) for patients with vertebral fractures. Methods: Nine female patients with osteoporosis participated in the pre-validation study. A validation, case-control study included two groups of female patients: one that consisted of 50 female patients with osteoporosis, and with at least one vertebral fracture, and another one that consisted of 50 control patients with osteoporosis but without fractures. They completed the QUALEFFO-41 and the EuroQol group questionnaire with five dimensions (EQ-5D) twice within a month. The validation study examined internal consistency, concurrent validity, test-retest reliability, sensitivity and specificity. Results: During the pre-validation study, three of the items in the QUALEFFO-41 were slightly changed. Afterwards, during the validation study, the statistically significant differences (adjusted for: age, duration of menopause, current employment and marital status) in the mean values of all domains and total scores between the groups were noted. For the case group, the internal consistency of the QUALEFFO-41 domains and of total questionnaire was above 0.70. The test-retest reliability was tested by the intraclass correlation coefficients (ICC) that were in range 0.87 - 0.96 for the case, and 0.15 - 0.83 for the control group. Correlations between the total scores of the QUALEFFO-41 and the EQ-5D health state value, for both groups were negative and statistically significant (r = -0.78, p lt 0.001 and r = -0.73, p lt 0.001, respectively). The QUALEFFO-41 had a better prediction of the value of HRQOL of cases compared to the generic questionnaire EQ-5D (the AUC difference was 0.099, p = 0.013). Conclusions: The Serbian QUALEFFO-41 version is reliable, valid, sensitive and predictive for examinations of HRQOL in patients with prevalent vertebral fractures and can be used in further studies.",
publisher = "Biomed Central Ltd, London",
journal = "Health and Quality of Life Outcomes",
title = "Validation of the osteoporosis quality of life questionnaire QUALEFFO-41 for the Serbian population",
volume = "10",
doi = "10.1186/1477-7525-10-74"
}

Tadić, I., Vujasinović-Stupar, N., Tasić, L., Stevanović, D., Dimić, A., Stamenković, B., Stojanović, S.,& Milenković, S.. (2012). Validation of the osteoporosis quality of life questionnaire QUALEFFO-41 for the Serbian population. in Health and Quality of Life Outcomes
Biomed Central Ltd, London., 10.
https://doi.org/10.1186/1477-7525-10-74

Tadić I, Vujasinović-Stupar N, Tasić L, Stevanović D, Dimić A, Stamenković B, Stojanović S, Milenković S. Validation of the osteoporosis quality of life questionnaire QUALEFFO-41 for the Serbian population. in Health and Quality of Life Outcomes. 2012;10.
doi:10.1186/1477-7525-10-74 .

Tadić, Ivana, Vujasinović-Stupar, Nada, Tasić, Ljiljana, Stevanović, Dejan, Dimić, Aleksandar, Stamenković, Bojana, Stojanović, Sonja, Milenković, Sasa, "Validation of the osteoporosis quality of life questionnaire QUALEFFO-41 for the Serbian population" in Health and Quality of Life Outcomes, 10 (2012),
https://doi.org/10.1186/1477-7525-10-74 . .