TY  - JOUR
AU  - Injac, Rade
AU  - Kac, Javor
AU  - Karljiković-Rajić, Katarina
AU  - Štrukelj, Borut
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1110
AB  - A micellar electrokinetic capillary chromatography was performed at 25 degrees C and 30 kV (under pressure of 15 mbar), with 30 mM berate buffer (pH 9.0), 60 mM sodium dodecysulfate, and 10% (v/v) ethanol as background electrolyte for the determination of sulfamethoxazole and trimethoprim. UV detection was at 205 nm. Recoveries were optimal and acceptable after extraction with ethanol / deionized water (1:1, v/v) for both investigated compounds from laboratory mixtures of standards. The method was shown to be specific, accurate (recoveries were 99.9 +/- 0.4% for sulfamethoxazole and 99.8 +/- 0.3% for trimethoprim), linear over the tested ranges (correlation coefficients >= 0.9990) and precise (RSD below 0.6%). The method was applied to determine sulfamethoxazole and trimethoprim in tablets, powder for cutaneous use and solution for infusion.
PB  - Food & Drug Adminstration, Taipei
T2  - Journal of Food and Drug Analysis
T1  - Optimal conditions for extraction and simultaneous determination of sulfamethoxazole and trimethoprim in pharmaceuticals by micellar electrokinetic capillary chromatography
VL  - 16
IS  - 1
SP  - 18
EP  - 25
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1110
ER  - 

@article{
author = "Injac, Rade and Kac, Javor and Karljiković-Rajić, Katarina and Štrukelj, Borut",
year = "2008",
abstract = "A micellar electrokinetic capillary chromatography was performed at 25 degrees C and 30 kV (under pressure of 15 mbar), with 30 mM berate buffer (pH 9.0), 60 mM sodium dodecysulfate, and 10% (v/v) ethanol as background electrolyte for the determination of sulfamethoxazole and trimethoprim. UV detection was at 205 nm. Recoveries were optimal and acceptable after extraction with ethanol / deionized water (1:1, v/v) for both investigated compounds from laboratory mixtures of standards. The method was shown to be specific, accurate (recoveries were 99.9 +/- 0.4% for sulfamethoxazole and 99.8 +/- 0.3% for trimethoprim), linear over the tested ranges (correlation coefficients >= 0.9990) and precise (RSD below 0.6%). The method was applied to determine sulfamethoxazole and trimethoprim in tablets, powder for cutaneous use and solution for infusion.",
publisher = "Food & Drug Adminstration, Taipei",
journal = "Journal of Food and Drug Analysis",
title = "Optimal conditions for extraction and simultaneous determination of sulfamethoxazole and trimethoprim in pharmaceuticals by micellar electrokinetic capillary chromatography",
volume = "16",
number = "1",
pages = "18-25",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1110"
}

Injac, R., Kac, J., Karljiković-Rajić, K.,& Štrukelj, B.. (2008). Optimal conditions for extraction and simultaneous determination of sulfamethoxazole and trimethoprim in pharmaceuticals by micellar electrokinetic capillary chromatography. in Journal of Food and Drug Analysis
Food & Drug Adminstration, Taipei., 16(1), 18-25.
https://hdl.handle.net/21.15107/rcub_farfar_1110

Injac R, Kac J, Karljiković-Rajić K, Štrukelj B. Optimal conditions for extraction and simultaneous determination of sulfamethoxazole and trimethoprim in pharmaceuticals by micellar electrokinetic capillary chromatography. in Journal of Food and Drug Analysis. 2008;16(1):18-25.
https://hdl.handle.net/21.15107/rcub_farfar_1110 .

Injac, Rade, Kac, Javor, Karljiković-Rajić, Katarina, Štrukelj, Borut, "Optimal conditions for extraction and simultaneous determination of sulfamethoxazole and trimethoprim in pharmaceuticals by micellar electrokinetic capillary chromatography" in Journal of Food and Drug Analysis, 16, no. 1 (2008):18-25,
https://hdl.handle.net/21.15107/rcub_farfar_1110 .

TY  - JOUR
AU  - Injac, Rade
AU  - Kac, Javor
AU  - Mlinarić, Ales
AU  - Karljiković-Rajić, Katarina
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/825
AB  - An MEKC procedure was developed for the separation of zinc bacitracin (Zn-BC) and nystatin (NYS) in mixtures and in animal feedstuff. The running buffer was 15 mM borate/19 mM phosphate, pH 8.2, containing 20 mM SDS and 10% v/v methanol. Samples were run at 25 degrees C, the applied voltage was 25 IN, and an additional pressure of 5 mbar was applied. Both analytes were detected by LTV simultaneously at 215 nm, Zn-BC alone at 192 and 254 nm, and NYS alone at 305 nm. The method was shown to be specific, accurate (recoveries were 100.0 +/- 0.6% and 100.1 +/- 0.6% for Zn-BC and NYS, respectively), linear over the tested range (correlation coefficients 0.9991 and 0.9994), and precise (RSD below 1.3% for both analytes). The method was applied to determine Zn-BC and NYS as additives in animal feed.
PB  - Wiley-VCH Verlag GMBH, Weinheim
T2  - Journal of Separation Science
T1  - Micellar electrokinetic capillary chromatography determination of zinc bacitracin and nystatin in animal feed
VL  - 29
IS  - 9
SP  - 1288
EP  - 1293
DO  - 10.1002/jssc.200500477
ER  - 

@article{
author = "Injac, Rade and Kac, Javor and Mlinarić, Ales and Karljiković-Rajić, Katarina",
year = "2006",
abstract = "An MEKC procedure was developed for the separation of zinc bacitracin (Zn-BC) and nystatin (NYS) in mixtures and in animal feedstuff. The running buffer was 15 mM borate/19 mM phosphate, pH 8.2, containing 20 mM SDS and 10% v/v methanol. Samples were run at 25 degrees C, the applied voltage was 25 IN, and an additional pressure of 5 mbar was applied. Both analytes were detected by LTV simultaneously at 215 nm, Zn-BC alone at 192 and 254 nm, and NYS alone at 305 nm. The method was shown to be specific, accurate (recoveries were 100.0 +/- 0.6% and 100.1 +/- 0.6% for Zn-BC and NYS, respectively), linear over the tested range (correlation coefficients 0.9991 and 0.9994), and precise (RSD below 1.3% for both analytes). The method was applied to determine Zn-BC and NYS as additives in animal feed.",
publisher = "Wiley-VCH Verlag GMBH, Weinheim",
journal = "Journal of Separation Science",
title = "Micellar electrokinetic capillary chromatography determination of zinc bacitracin and nystatin in animal feed",
volume = "29",
number = "9",
pages = "1288-1293",
doi = "10.1002/jssc.200500477"
}

Injac, R., Kac, J., Mlinarić, A.,& Karljiković-Rajić, K.. (2006). Micellar electrokinetic capillary chromatography determination of zinc bacitracin and nystatin in animal feed. in Journal of Separation Science
Wiley-VCH Verlag GMBH, Weinheim., 29(9), 1288-1293.
https://doi.org/10.1002/jssc.200500477

Injac R, Kac J, Mlinarić A, Karljiković-Rajić K. Micellar electrokinetic capillary chromatography determination of zinc bacitracin and nystatin in animal feed. in Journal of Separation Science. 2006;29(9):1288-1293.
doi:10.1002/jssc.200500477 .

Injac, Rade, Kac, Javor, Mlinarić, Ales, Karljiković-Rajić, Katarina, "Micellar electrokinetic capillary chromatography determination of zinc bacitracin and nystatin in animal feed" in Journal of Separation Science, 29, no. 9 (2006):1288-1293,
https://doi.org/10.1002/jssc.200500477 . .