TY  - JOUR
AU  - Negrojević, Luka
AU  - Lončar, Aleksandar
AU  - Maksimović, Jelena
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
AU  - Pejić, Nataša
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4022
AB  - A kinetic method for the determination of l-tyrosine (Tyr) by analyte pulse perturbation, caused by different amounts of Tyr, in the Bray–Liebhafsky (BL) oscillatory reaction realized in a continuous-flow stirred tank reactor, is proposed. For such purposes, the BL oscillating reaction was kept in a stable non-equilibrium stationary state close to the bifurcation point and was used as the matrix reaction system. Under optimum reaction conditions, the linear relationship between the kinetic parameters, Δτ2 (the period between first two oscillations that appear after applied perturbation) as well as τend (the time elapsed between the perturbation of the BL reaction by Tyr and the termination of the oscillatory phase) and the Tyr concentrations is obtained over the ranges 1.1 × 10− 6 − 9.2 × 10− 6 mol L− 1 and 1.1 × 10− 6 − 1.4 × 10− 5 mol L− 1, with the limit of detections of 6.6 × 10− 7 mol L− 1 and 6.4 × 10− 7 mol L− 1. The described method that relies on a simple instrumental set-up, has been successfully applied to the determination of Tyr in a dietary supplement. Some aspects of the possible mechanism of Tyr action on the BL oscillator are discussed.
PB  - Springer Science and Business Media B.V.
T2  - Reaction Kinetics, Mechanisms and Catalysis
T1  - Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine
DO  - 10.1007/s11144-021-02130-5
ER  - 

@article{
author = "Negrojević, Luka and Lončar, Aleksandar and Maksimović, Jelena and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana and Pejić, Nataša",
year = "2022",
abstract = "A kinetic method for the determination of l-tyrosine (Tyr) by analyte pulse perturbation, caused by different amounts of Tyr, in the Bray–Liebhafsky (BL) oscillatory reaction realized in a continuous-flow stirred tank reactor, is proposed. For such purposes, the BL oscillating reaction was kept in a stable non-equilibrium stationary state close to the bifurcation point and was used as the matrix reaction system. Under optimum reaction conditions, the linear relationship between the kinetic parameters, Δτ2 (the period between first two oscillations that appear after applied perturbation) as well as τend (the time elapsed between the perturbation of the BL reaction by Tyr and the termination of the oscillatory phase) and the Tyr concentrations is obtained over the ranges 1.1 × 10− 6 − 9.2 × 10− 6 mol L− 1 and 1.1 × 10− 6 − 1.4 × 10− 5 mol L− 1, with the limit of detections of 6.6 × 10− 7 mol L− 1 and 6.4 × 10− 7 mol L− 1. The described method that relies on a simple instrumental set-up, has been successfully applied to the determination of Tyr in a dietary supplement. Some aspects of the possible mechanism of Tyr action on the BL oscillator are discussed.",
publisher = "Springer Science and Business Media B.V.",
journal = "Reaction Kinetics, Mechanisms and Catalysis",
title = "Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine",
doi = "10.1007/s11144-021-02130-5"
}

Negrojević, L., Lončar, A., Maksimović, J., Anić, S., Čupić, Ž., Kolar-Anić, L.,& Pejić, N.. (2022). Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine. in Reaction Kinetics, Mechanisms and Catalysis
Springer Science and Business Media B.V...
https://doi.org/10.1007/s11144-021-02130-5

Negrojević L, Lončar A, Maksimović J, Anić S, Čupić Ž, Kolar-Anić L, Pejić N. Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine. in Reaction Kinetics, Mechanisms and Catalysis. 2022;.
doi:10.1007/s11144-021-02130-5 .

Negrojević, Luka, Lončar, Aleksandar, Maksimović, Jelena, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, Pejić, Nataša, "Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine" in Reaction Kinetics, Mechanisms and Catalysis (2022),
https://doi.org/10.1007/s11144-021-02130-5 . .

TY  - JOUR
AU  - Macesić, Stevan
AU  - Čupić, Željko
AU  - Ivanović-Sasić, Ana
AU  - Anić, Slobodan
AU  - Radenković, Mirjana
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3203
AB  - In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained system's dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Bifurcation analysis: a tool for determining model parameters of the considered process
VL  - 123
IS  - 1
SP  - 31
EP  - 45
DO  - 10.1007/s11144-017-1324-6
ER  - 

@article{
author = "Macesić, Stevan and Čupić, Željko and Ivanović-Sasić, Ana and Anić, Slobodan and Radenković, Mirjana and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2018",
abstract = "In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained system's dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Bifurcation analysis: a tool for determining model parameters of the considered process",
volume = "123",
number = "1",
pages = "31-45",
doi = "10.1007/s11144-017-1324-6"
}

Macesić, S., Čupić, Ž., Ivanović-Sasić, A., Anić, S., Radenković, M., Pejić, N.,& Kolar-Anić, L.. (2018). Bifurcation analysis: a tool for determining model parameters of the considered process. in Records of Natural Products
Springer, Dordrecht., 123(1), 31-45.
https://doi.org/10.1007/s11144-017-1324-6

Macesić S, Čupić Ž, Ivanović-Sasić A, Anić S, Radenković M, Pejić N, Kolar-Anić L. Bifurcation analysis: a tool for determining model parameters of the considered process. in Records of Natural Products. 2018;123(1):31-45.
doi:10.1007/s11144-017-1324-6 .

Macesić, Stevan, Čupić, Željko, Ivanović-Sasić, Ana, Anić, Slobodan, Radenković, Mirjana, Pejić, Nataša, Kolar-Anić, Ljiljana, "Bifurcation analysis: a tool for determining model parameters of the considered process" in Records of Natural Products, 123, no. 1 (2018):31-45,
https://doi.org/10.1007/s11144-017-1324-6 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
AU  - Maksimović, Jelena
AU  - Janković, Marija
AU  - Vukojević, Vladana
AU  - Anić, Slobodan
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2528
AB  - The temporal dynamics of the Bray-Liebhafsky reaction (iodate-based catalytic decomposition of hydrogen peroxide in an acidic aqueous solution) was experimentally characterized in a continuous stirred tank reactor by independently varying the temperature and the mixed inflow hydrogen peroxide concentration. When the temperature was the bifurcation parameter, the emergence/disappearance of oscillatory behavior via a supercritical Andronov-Hopf bifurcation was observed for different mixed inflow hydrogen peroxide concentrations. An increase in the mixed inflow hydrogen-peroxide concentration resulted in a shift of the bifurcation point towards higher values of temperature, but did not alter the bifurcation type.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation
VL  - 118
IS  - 1
SP  - 15
EP  - 26
DO  - 10.1007/s11144-016-0984-y
ER  - 

@article{
author = "Pejić, Nataša and Kolar-Anić, Ljiljana and Maksimović, Jelena and Janković, Marija and Vukojević, Vladana and Anić, Slobodan",
year = "2016",
abstract = "The temporal dynamics of the Bray-Liebhafsky reaction (iodate-based catalytic decomposition of hydrogen peroxide in an acidic aqueous solution) was experimentally characterized in a continuous stirred tank reactor by independently varying the temperature and the mixed inflow hydrogen peroxide concentration. When the temperature was the bifurcation parameter, the emergence/disappearance of oscillatory behavior via a supercritical Andronov-Hopf bifurcation was observed for different mixed inflow hydrogen peroxide concentrations. An increase in the mixed inflow hydrogen-peroxide concentration resulted in a shift of the bifurcation point towards higher values of temperature, but did not alter the bifurcation type.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation",
volume = "118",
number = "1",
pages = "15-26",
doi = "10.1007/s11144-016-0984-y"
}

Pejić, N., Kolar-Anić, L., Maksimović, J., Janković, M., Vukojević, V.,& Anić, S.. (2016). Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation. in Records of Natural Products
Springer, Dordrecht., 118(1), 15-26.
https://doi.org/10.1007/s11144-016-0984-y

Pejić N, Kolar-Anić L, Maksimović J, Janković M, Vukojević V, Anić S. Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation. in Records of Natural Products. 2016;118(1):15-26.
doi:10.1007/s11144-016-0984-y .

Pejić, Nataša, Kolar-Anić, Ljiljana, Maksimović, Jelena, Janković, Marija, Vukojević, Vladana, Anić, Slobodan, "Dynamic transitions in the Bray-Liebhafsky oscillating reaction. Effect of hydrogen peroxide and temperature on bifurcation" in Records of Natural Products, 118, no. 1 (2016):15-26,
https://doi.org/10.1007/s11144-016-0984-y . .

TY  - JOUR
AU  - Čupić, Željko
AU  - Ivanović-Sasic, Ana
AU  - Blagojevic, Stevan
AU  - Blagojević, Slavica
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2545
AB  - By numerically simulated Bray-Liebhafsky (BL) reaction under a continuously fed well stirred tank reactor (CSTR) conditions, we discussed the attractors and Poincar, 1D maps with respect to flow rate as the control parameter. The new technique of the return maps from transient trajectories over the slow manifold is developed and applied in order to explore its multilayered structure related to dynamical states (periodic and aperiodic -chaotic oscillating modes) of the system. Kinetic relations underlying the slow manifold structure are briefly discussed.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model
VL  - 118
IS  - 1
SP  - 27
EP  - 38
DO  - 10.1007/s11144-016-0998-5
ER  - 

@article{
author = "Čupić, Željko and Ivanović-Sasic, Ana and Blagojevic, Stevan and Blagojević, Slavica and Kolar-Anić, Ljiljana and Anić, Slobodan",
year = "2016",
abstract = "By numerically simulated Bray-Liebhafsky (BL) reaction under a continuously fed well stirred tank reactor (CSTR) conditions, we discussed the attractors and Poincar, 1D maps with respect to flow rate as the control parameter. The new technique of the return maps from transient trajectories over the slow manifold is developed and applied in order to explore its multilayered structure related to dynamical states (periodic and aperiodic -chaotic oscillating modes) of the system. Kinetic relations underlying the slow manifold structure are briefly discussed.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model",
volume = "118",
number = "1",
pages = "27-38",
doi = "10.1007/s11144-016-0998-5"
}

Čupić, Ž., Ivanović-Sasic, A., Blagojevic, S., Blagojević, S., Kolar-Anić, L.,& Anić, S.. (2016). Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model. in Records of Natural Products
Springer, Dordrecht., 118(1), 27-38.
https://doi.org/10.1007/s11144-016-0998-5

Čupić Ž, Ivanović-Sasic A, Blagojevic S, Blagojević S, Kolar-Anić L, Anić S. Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model. in Records of Natural Products. 2016;118(1):27-38.
doi:10.1007/s11144-016-0998-5 .

Čupić, Željko, Ivanović-Sasic, Ana, Blagojevic, Stevan, Blagojević, Slavica, Kolar-Anić, Ljiljana, Anić, Slobodan, "Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model" in Records of Natural Products, 118, no. 1 (2016):27-38,
https://doi.org/10.1007/s11144-016-0998-5 . .

TY  - JOUR
AU  - Stanković, Branislav
AU  - Čupić, Željko
AU  - Macesić, Stevan
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2542
AB  - The mixing of different types of bifurcations, i.e. supercritical Andronov-Hopf (SAH), double loop (DL) and saddle-loop (SL) bifurcations in the vicinity of their total annihilation, is examined on the highly nonlinear six-variable model for the Bray-Liebhafsky (BL) oscillatory reaction under continuously well-stirred tank reactor (CSTR) conditions. For this kind of the reaction system where the law of mass conservation is additional constraint that must be satisfied and where because of that, some simple bifurcations cannot be formed independently to the others, the considered transformations of the bifurcations are particularly important. That is why as the control parameters for bifurcation analysis, the specific flow rate (j(0)), as well as the inflow hydrogen peroxide concentration (h = [H2O2](in)), were used. The complex bifurcations obtained from numerical simulations are compared with some experimental results. It was shown that these complex bifurcations cannot be easily recognized in experimental investigations without knowing their evolution.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Chaos Solitons & Fractals
T1  - Complex bifurcations in the oscillatory reaction model
VL  - 87
SP  - 84
EP  - 91
DO  - 10.1016/j.chaos.2016.03.013
ER  - 

@article{
author = "Stanković, Branislav and Čupić, Željko and Macesić, Stevan and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2016",
abstract = "The mixing of different types of bifurcations, i.e. supercritical Andronov-Hopf (SAH), double loop (DL) and saddle-loop (SL) bifurcations in the vicinity of their total annihilation, is examined on the highly nonlinear six-variable model for the Bray-Liebhafsky (BL) oscillatory reaction under continuously well-stirred tank reactor (CSTR) conditions. For this kind of the reaction system where the law of mass conservation is additional constraint that must be satisfied and where because of that, some simple bifurcations cannot be formed independently to the others, the considered transformations of the bifurcations are particularly important. That is why as the control parameters for bifurcation analysis, the specific flow rate (j(0)), as well as the inflow hydrogen peroxide concentration (h = [H2O2](in)), were used. The complex bifurcations obtained from numerical simulations are compared with some experimental results. It was shown that these complex bifurcations cannot be easily recognized in experimental investigations without knowing their evolution.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Chaos Solitons & Fractals",
title = "Complex bifurcations in the oscillatory reaction model",
volume = "87",
pages = "84-91",
doi = "10.1016/j.chaos.2016.03.013"
}

Stanković, B., Čupić, Ž., Macesić, S., Pejić, N.,& Kolar-Anić, L.. (2016). Complex bifurcations in the oscillatory reaction model. in Chaos Solitons & Fractals
Pergamon-Elsevier Science Ltd, Oxford., 87, 84-91.
https://doi.org/10.1016/j.chaos.2016.03.013

Stanković B, Čupić Ž, Macesić S, Pejić N, Kolar-Anić L. Complex bifurcations in the oscillatory reaction model. in Chaos Solitons & Fractals. 2016;87:84-91.
doi:10.1016/j.chaos.2016.03.013 .

Stanković, Branislav, Čupić, Željko, Macesić, Stevan, Pejić, Nataša, Kolar-Anić, Ljiljana, "Complex bifurcations in the oscillatory reaction model" in Chaos Solitons & Fractals, 87 (2016):84-91,
https://doi.org/10.1016/j.chaos.2016.03.013 . .

TY  - JOUR
AU  - Macesic, Stevan R.
AU  - Čupić, Željko
AU  - Blagojević, Slavica
AU  - Pejić, Nataša
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2455
AB  - In stoichiometric network analysis (SNA) the instability condition is calculated by the current rates. Recently, we have shown that in the final result the current rates can be substituted by reaction rates, which is a more appropriate value for the examination of instability from experimental point of view. Here, we elaborate the problem of whether the current rates are necessary parameters in the calculation, with the aim of obtaining the region of instability. All calculations are performed on a model for Belousov-Zhabotinsky (BZ) reaction, which has not been examined by SNA.
PB  - De Gruyter Open Ltd, Warsaw
T2  - Open Chemistry
T1  - Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)
VL  - 13
IS  - 1
SP  - 591
EP  - 599
DO  - 10.1515/chem-2015-0077
ER  - 

@article{
author = "Macesic, Stevan R. and Čupić, Željko and Blagojević, Slavica and Pejić, Nataša and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2015",
abstract = "In stoichiometric network analysis (SNA) the instability condition is calculated by the current rates. Recently, we have shown that in the final result the current rates can be substituted by reaction rates, which is a more appropriate value for the examination of instability from experimental point of view. Here, we elaborate the problem of whether the current rates are necessary parameters in the calculation, with the aim of obtaining the region of instability. All calculations are performed on a model for Belousov-Zhabotinsky (BZ) reaction, which has not been examined by SNA.",
publisher = "De Gruyter Open Ltd, Warsaw",
journal = "Open Chemistry",
title = "Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)",
volume = "13",
number = "1",
pages = "591-599",
doi = "10.1515/chem-2015-0077"
}

Macesic, S. R., Čupić, Ž., Blagojević, S., Pejić, N., Anić, S.,& Kolar-Anić, L.. (2015). Current rates and reaction rates in the Stoichiometric Network Analysis (SNA). in Open Chemistry
De Gruyter Open Ltd, Warsaw., 13(1), 591-599.
https://doi.org/10.1515/chem-2015-0077

Macesic SR, Čupić Ž, Blagojević S, Pejić N, Anić S, Kolar-Anić L. Current rates and reaction rates in the Stoichiometric Network Analysis (SNA). in Open Chemistry. 2015;13(1):591-599.
doi:10.1515/chem-2015-0077 .

Macesic, Stevan R., Čupić, Željko, Blagojević, Slavica, Pejić, Nataša, Anić, Slobodan, Kolar-Anić, Ljiljana, "Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)" in Open Chemistry, 13, no. 1 (2015):591-599,
https://doi.org/10.1515/chem-2015-0077 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Sarap, Nataša B.
AU  - Maksimović, Jelena
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2172
AB  - Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.
PB  - Wiley-VCH Verlag GMBH, Weinheim
T2  - Helvetica Chimica Acta
T1  - Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations
VL  - 97
IS  - 1
SP  - 47
EP  - 55
DO  - 10.1002/hlca.201300109
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Sarap, Nataša B. and Maksimović, Jelena and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2014",
abstract = "Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.",
publisher = "Wiley-VCH Verlag GMBH, Weinheim",
journal = "Helvetica Chimica Acta",
title = "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations",
volume = "97",
number = "1",
pages = "47-55",
doi = "10.1002/hlca.201300109"
}

Pejić, N., Blagojević, S., Sarap, N. B., Maksimović, J., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2014). Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta
Wiley-VCH Verlag GMBH, Weinheim., 97(1), 47-55.
https://doi.org/10.1002/hlca.201300109

Pejić N, Blagojević S, Sarap NB, Maksimović J, Anić S, Čupić Ž, Kolar-Anić L. Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta. 2014;97(1):47-55.
doi:10.1002/hlca.201300109 .

Pejić, Nataša, Blagojević, Slavica, Sarap, Nataša B., Maksimović, Jelena, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations" in Helvetica Chimica Acta, 97, no. 1 (2014):47-55,
https://doi.org/10.1002/hlca.201300109 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Sarap, Nataša B.
AU  - Maksimović, Jelena
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1940
AB  - A simple and reliable novel kinetic method for the determination of piroxicam (PX) was proposed and validated. For quantitative determination of PX, the Bray-Liebhafsky (BL) oscillatory reaction was used in a stable non-equilibrium stationary state close to the bifurcation point. Under the optimized reaction conditions (T = 55.0A degrees C, [H2SO4](0) = 7.60x10(-2) mol L-1, [KIO3](0) = 5.90x10(-2) mol L-1, [H2O2](0) = 1.50x10(-1) mol L-1 and j (0) = 2.95x10(-2) min(-1)), the linear relationship between maximal potential shift Delta E (m) , and PX concentration was obtained in the concentration range 11.2-480.5 A mu g mL(-1) with a detection limit of 9.9 A mu g mL(-1). The method had a rather good sample throughput of 25 samples h(-1) with a precision RSD = 4.7% as well as recoveries RCV a parts per thousand currency sign 104.4%. Applicability of the proposed method to the direct determination of piroxicam in different pharmaceutical formulations (tablets, ampoules and gel) was demonstrated.
PB  - Versita, Warsaw
T2  - Central European Journal of Chemistry
T1  - Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system
VL  - 11
IS  - 2
SP  - 180
EP  - 188
DO  - 10.2478/s11532-012-0146-7
ER  - 

@article{
author = "Pejić, Nataša and Sarap, Nataša B. and Maksimović, Jelena and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2013",
abstract = "A simple and reliable novel kinetic method for the determination of piroxicam (PX) was proposed and validated. For quantitative determination of PX, the Bray-Liebhafsky (BL) oscillatory reaction was used in a stable non-equilibrium stationary state close to the bifurcation point. Under the optimized reaction conditions (T = 55.0A degrees C, [H2SO4](0) = 7.60x10(-2) mol L-1, [KIO3](0) = 5.90x10(-2) mol L-1, [H2O2](0) = 1.50x10(-1) mol L-1 and j (0) = 2.95x10(-2) min(-1)), the linear relationship between maximal potential shift Delta E (m) , and PX concentration was obtained in the concentration range 11.2-480.5 A mu g mL(-1) with a detection limit of 9.9 A mu g mL(-1). The method had a rather good sample throughput of 25 samples h(-1) with a precision RSD = 4.7% as well as recoveries RCV a parts per thousand currency sign 104.4%. Applicability of the proposed method to the direct determination of piroxicam in different pharmaceutical formulations (tablets, ampoules and gel) was demonstrated.",
publisher = "Versita, Warsaw",
journal = "Central European Journal of Chemistry",
title = "Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system",
volume = "11",
number = "2",
pages = "180-188",
doi = "10.2478/s11532-012-0146-7"
}

Pejić, N., Sarap, N. B., Maksimović, J., Anić, S.,& Kolar-Anić, L.. (2013). Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system. in Central European Journal of Chemistry
Versita, Warsaw., 11(2), 180-188.
https://doi.org/10.2478/s11532-012-0146-7

Pejić N, Sarap NB, Maksimović J, Anić S, Kolar-Anić L. Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system. in Central European Journal of Chemistry. 2013;11(2):180-188.
doi:10.2478/s11532-012-0146-7 .

Pejić, Nataša, Sarap, Nataša B., Maksimović, Jelena, Anić, Slobodan, Kolar-Anić, Ljiljana, "Pulse perturbation technique for determination of piroxicam in pharmaceuticals using an oscillatory reaction system" in Central European Journal of Chemistry, 11, no. 2 (2013):180-188,
https://doi.org/10.2478/s11532-012-0146-7 . .

TY  - JOUR
AU  - Stanković, Branislav
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2031
AB  - The time series obtained by numerical simulations of the model of the Bray-Liebhafsky oscillatory reaction is analyzed under the continuously fed well stirred tank reactor (CSTR) conditions, with the aim to find bifurcation points in which system of Bray- Liebhafsky oscillatory reaction transforms from stable to unstable state and vice versa. Types of bifurcation points, supercritical and subcritical Andronov-Hopf bifurcation and saddle-loop bifurcation are determined from characteristic scaling laws.
PB  - L and H Scientific Publishing, LLC
T2  - Journal of Applied Nonlinear Dynamics
T1  - Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations
VL  - 2
IS  - 3
SP  - 285
EP  - 301
DO  - 10.5890/JAND.2013.08.004
ER  - 

@article{
author = "Stanković, Branislav and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2013",
abstract = "The time series obtained by numerical simulations of the model of the Bray-Liebhafsky oscillatory reaction is analyzed under the continuously fed well stirred tank reactor (CSTR) conditions, with the aim to find bifurcation points in which system of Bray- Liebhafsky oscillatory reaction transforms from stable to unstable state and vice versa. Types of bifurcation points, supercritical and subcritical Andronov-Hopf bifurcation and saddle-loop bifurcation are determined from characteristic scaling laws.",
publisher = "L and H Scientific Publishing, LLC",
journal = "Journal of Applied Nonlinear Dynamics",
title = "Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations",
volume = "2",
number = "3",
pages = "285-301",
doi = "10.5890/JAND.2013.08.004"
}

Stanković, B., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2013). Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations. in Journal of Applied Nonlinear Dynamics
L and H Scientific Publishing, LLC., 2(3), 285-301.
https://doi.org/10.5890/JAND.2013.08.004

Stanković B, Čupić Ž, Pejić N, Kolar-Anić L. Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations. in Journal of Applied Nonlinear Dynamics. 2013;2(3):285-301.
doi:10.5890/JAND.2013.08.004 .

Stanković, Branislav, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations" in Journal of Applied Nonlinear Dynamics, 2, no. 3 (2013):285-301,
https://doi.org/10.5890/JAND.2013.08.004 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Maksimović, Jelena
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1655
AB  - Simple and reliable novel methods for the determination of uric acid (UA) are proposed and validated. For quantitative determination of UA, two matrices were used: the Bray-Liebhafsky (BL) oscillatory reaction in a stable non-equilibrium stationary state close to the bifurcation point (method A) as well as, the BL non-oscillating subsystem (mixture KIO3 and H2SO4), i.e., Dushman reaction (DR) in a steady state (method B). The proposed methods are optimized in a continuously fed well stirred tank reactor (CSTR) and applied with excellent results in the determination of UA in human urine samples. The linear relationship between maximal potential shift Delta E-m, and both the logarithm of the UA concentration (procedure A) and UA concentration (procedure B) is obtained in the concentration range 2.98 x 10(-5)-2.68 x 10(-4) mol L-1 and 2.98 x 10(-5)-3.58 x 10(-4) mol L-1, respectively. The methods have an excellent sample throughput of 30 samples h(-1) (method A) and 7 samples h(-1) (method B) with the sensitivity determined to be 1.1 x 10(-5) mol L-1 (method A) and 8.9 x 10(-6) mol L-1 (method B) as well as the precision RSD  lt = 3.4% for both methods. Some aspects of the possible mechanism of UA action on the BL oscillating and Duschman non-oscillating reaction systems are discussed in detail.
PB  - Soc Brasileira Quimica, Sao Paulo
T2  - Journal of the Brazilian Chemical Society
T1  - Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique
VL  - 23
IS  - 8
SP  - 1450
EP  - 1459
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1655
ER  - 

@article{
author = "Pejić, Nataša and Maksimović, Jelena and Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2012",
abstract = "Simple and reliable novel methods for the determination of uric acid (UA) are proposed and validated. For quantitative determination of UA, two matrices were used: the Bray-Liebhafsky (BL) oscillatory reaction in a stable non-equilibrium stationary state close to the bifurcation point (method A) as well as, the BL non-oscillating subsystem (mixture KIO3 and H2SO4), i.e., Dushman reaction (DR) in a steady state (method B). The proposed methods are optimized in a continuously fed well stirred tank reactor (CSTR) and applied with excellent results in the determination of UA in human urine samples. The linear relationship between maximal potential shift Delta E-m, and both the logarithm of the UA concentration (procedure A) and UA concentration (procedure B) is obtained in the concentration range 2.98 x 10(-5)-2.68 x 10(-4) mol L-1 and 2.98 x 10(-5)-3.58 x 10(-4) mol L-1, respectively. The methods have an excellent sample throughput of 30 samples h(-1) (method A) and 7 samples h(-1) (method B) with the sensitivity determined to be 1.1 x 10(-5) mol L-1 (method A) and 8.9 x 10(-6) mol L-1 (method B) as well as the precision RSD  lt = 3.4% for both methods. Some aspects of the possible mechanism of UA action on the BL oscillating and Duschman non-oscillating reaction systems are discussed in detail.",
publisher = "Soc Brasileira Quimica, Sao Paulo",
journal = "Journal of the Brazilian Chemical Society",
title = "Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique",
volume = "23",
number = "8",
pages = "1450-1459",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1655"
}

Pejić, N., Maksimović, J., Blagojević, S., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2012). Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique. in Journal of the Brazilian Chemical Society
Soc Brasileira Quimica, Sao Paulo., 23(8), 1450-1459.
https://hdl.handle.net/21.15107/rcub_farfar_1655

Pejić N, Maksimović J, Blagojević S, Anić S, Čupić Ž, Kolar-Anić L. Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique. in Journal of the Brazilian Chemical Society. 2012;23(8):1450-1459.
https://hdl.handle.net/21.15107/rcub_farfar_1655 .

Pejić, Nataša, Maksimović, Jelena, Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique" in Journal of the Brazilian Chemical Society, 23, no. 8 (2012):1450-1459,
https://hdl.handle.net/21.15107/rcub_farfar_1655 .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1770
AB  - Novel analytical methods for quantitive determination of analytes based on perturbations of oscillatory chemical reactions realized under open reactor conditions (continuosly fed well stirred tank reactor, CSTR), have been developed in the past twenty years. The proposed kinetic methods are generally based on the ability of the analyzed substances to change the kinetics of the chemical reactions matrix. The unambiguous correlation of quantitative characteristics of perturbations, and the amount (concentration) of analyte expressed as a regression equation, or its graphics (calibration curve), enable the determination of the unknown analyte concentration. Attention is given to the development of these methods because of their simple experimental procedures, broad range of linear regression (10-7-10-4 mol L-1) and low limits of detection of analytes (10-6-10-8 mol L-1, in some cases even lower than 10-12 mol L-1). Therefore, their application is very convenient for routine analysis of various inorganic and organic compounds as well as gases. This review summarizes progress made in the past 5 years on quantitative determination of pharmaceutically and biologically important compounds.
AB  - U poslednjih dvadesetak godina razvijene su brojne analitičke primene oscilatornih hemijskih reakcija realizovanih u otvorenom reaktoru. Predložene kinetičke metode se zasnivaju na sposobnosti analiziranih supstancija da menjaju kinetičke parametre hemijskih reakcija, pri čemu eksperimentalno dobijeni signal odražava reakcionu brzinu koja zavisi od koncentracije ispitivanog analita. Razvoju ovih metoda poklanja se sve veća pažnja zbog jednostavne eksperimentalne procedure, velikog linearnog opsega regresione jednačine (10-7-10-4 mol L-1) i niskog limita detekcije (10-6-10-8 mol L-1, u nekim slučajevima, ? 10-12 mol L-1), a njihovo korišćenje je vrlo pogodno za rutinske analize različitih neorganskih i organskih jedinjenja, kao i gasova. Ovaj rad ima za cilj da dâ kratki pregled primene takozvane pulsne perturbacione tehnike za kvantitativna određivanja nekih farmaceutski i biološki važnih jedinjenja u periodu od druge polovine 2005. godine do prve polovine 2011. godine.
PB  - Savez hemijskih inženjera, Beograd
T2  - Hemijska industrija
T1  - Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds
T1  - Analitičke primene oscilatornih hemijskih reakcija - određivanje nekih farmaceutskih i biološki važnih jedinjenja
VL  - 66
IS  - 2
SP  - 153
EP  - 164
DO  - 10.2298/HEMIND110912081P
ER  - 

@article{
author = "Pejić, Nataša and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2012",
abstract = "Novel analytical methods for quantitive determination of analytes based on perturbations of oscillatory chemical reactions realized under open reactor conditions (continuosly fed well stirred tank reactor, CSTR), have been developed in the past twenty years. The proposed kinetic methods are generally based on the ability of the analyzed substances to change the kinetics of the chemical reactions matrix. The unambiguous correlation of quantitative characteristics of perturbations, and the amount (concentration) of analyte expressed as a regression equation, or its graphics (calibration curve), enable the determination of the unknown analyte concentration. Attention is given to the development of these methods because of their simple experimental procedures, broad range of linear regression (10-7-10-4 mol L-1) and low limits of detection of analytes (10-6-10-8 mol L-1, in some cases even lower than 10-12 mol L-1). Therefore, their application is very convenient for routine analysis of various inorganic and organic compounds as well as gases. This review summarizes progress made in the past 5 years on quantitative determination of pharmaceutically and biologically important compounds., U poslednjih dvadesetak godina razvijene su brojne analitičke primene oscilatornih hemijskih reakcija realizovanih u otvorenom reaktoru. Predložene kinetičke metode se zasnivaju na sposobnosti analiziranih supstancija da menjaju kinetičke parametre hemijskih reakcija, pri čemu eksperimentalno dobijeni signal odražava reakcionu brzinu koja zavisi od koncentracije ispitivanog analita. Razvoju ovih metoda poklanja se sve veća pažnja zbog jednostavne eksperimentalne procedure, velikog linearnog opsega regresione jednačine (10-7-10-4 mol L-1) i niskog limita detekcije (10-6-10-8 mol L-1, u nekim slučajevima, ? 10-12 mol L-1), a njihovo korišćenje je vrlo pogodno za rutinske analize različitih neorganskih i organskih jedinjenja, kao i gasova. Ovaj rad ima za cilj da dâ kratki pregled primene takozvane pulsne perturbacione tehnike za kvantitativna određivanja nekih farmaceutski i biološki važnih jedinjenja u periodu od druge polovine 2005. godine do prve polovine 2011. godine.",
publisher = "Savez hemijskih inženjera, Beograd",
journal = "Hemijska industrija",
title = "Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds, Analitičke primene oscilatornih hemijskih reakcija - određivanje nekih farmaceutskih i biološki važnih jedinjenja",
volume = "66",
number = "2",
pages = "153-164",
doi = "10.2298/HEMIND110912081P"
}

Pejić, N., Anić, S.,& Kolar-Anić, L.. (2012). Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds. in Hemijska industrija
Savez hemijskih inženjera, Beograd., 66(2), 153-164.
https://doi.org/10.2298/HEMIND110912081P

Pejić N, Anić S, Kolar-Anić L. Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds. in Hemijska industrija. 2012;66(2):153-164.
doi:10.2298/HEMIND110912081P .

Pejić, Nataša, Anić, Slobodan, Kolar-Anić, Ljiljana, "Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds" in Hemijska industrija, 66, no. 2 (2012):153-164,
https://doi.org/10.2298/HEMIND110912081P . .

TY  - JOUR
AU  - Maksimović, Jelena
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
AU  - Ribić, Dragana D.
AU  - Pejić, Nataša
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1536
AB  - A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.
PB  - Soc Brasileira Quimica, Sao Paulo
T2  - Journal of the Brazilian Chemical Society
T1  - Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction
VL  - 22
IS  - 1
SP  - 38
EP  - 48
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1536
ER  - 

@article{
author = "Maksimović, Jelena and Kolar-Anić, Ljiljana and Anić, Slobodan and Ribić, Dragana D. and Pejić, Nataša",
year = "2011",
abstract = "A novel procedure for kinetic determination of some water-soluble vitamins of the B-group (thiamine (B-1), riboflavin (B-2), niacin (B-3) and pyridoxine (B-6)) by the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory chemical system involving the catalytic decomposition of hydrogen peroxide in the presence of both hydrogen and iodate ions is proposed and validated. The method uses a Pt electrode for potentiometric monitoring of the concentration perturbations of the BL matrix in a stable non-equilibrium stationary state close to the bifurcation point. The proposed method relies on the linear relationship between maximal potential displacements, Delta E-m, caused by the additional known quantities of a B species. Under the optimal established analytical conditions, linear calibration curves were obtained over the range of 0.01-1.0, 0.016-0.128, 5.0-50.0 and 0.05-2.5 mu mol with the limits of detection of 0.01, 0.018, 2.6 and 0.03 mu mol, as well as analytical throughput of 30, 5, 12 and 20 determinations per hour, for B-1, B-2, B-3 and B-6, respectively. The used technical approach also provides simple, effective and convenient method to assay the pharmaceutical formulations containing B-1 together with other active principles such as nicotinamide and vitamin B-12 as well as B-3.",
publisher = "Soc Brasileira Quimica, Sao Paulo",
journal = "Journal of the Brazilian Chemical Society",
title = "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction",
volume = "22",
number = "1",
pages = "38-48",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1536"
}

Maksimović, J., Kolar-Anić, L., Anić, S., Ribić, D. D.,& Pejić, N.. (2011). Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society
Soc Brasileira Quimica, Sao Paulo., 22(1), 38-48.
https://hdl.handle.net/21.15107/rcub_farfar_1536

Maksimović J, Kolar-Anić L, Anić S, Ribić DD, Pejić N. Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction. in Journal of the Brazilian Chemical Society. 2011;22(1):38-48.
https://hdl.handle.net/21.15107/rcub_farfar_1536 .

Maksimović, Jelena, Kolar-Anić, Ljiljana, Anić, Slobodan, Ribić, Dragana D., Pejić, Nataša, "Quantitative Determination of Some Water-Soluble B Vitamins by Kinetic Analytical Method Based on the Perturbation of an Oscillatory Reaction" in Journal of the Brazilian Chemical Society, 22, no. 1 (2011):38-48,
https://hdl.handle.net/21.15107/rcub_farfar_1536 .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Vujković, Milica
AU  - Maksimović, Jelena
AU  - Ivanović, A.
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1516
AB  - The non-periodic, periodic and chaotic regimes in the Bray-Liebhafsky (BL) oscillatory reaction observed in a continuously fed well stirred tank reactor (CSTR) under isothermal conditions at various inflow concentrations of the sulfuric acid were experimentally studied. In each series (at any fixed temperature), termination of oscillatory behavior via saddle loop infinite period bifurcation (SNIPER) as well as some kind of the Andronov-Hopf bifurcation is presented. In addition, it was found that an increase of temperature, in different series of experiments resulted in the shift of bifurcation point towards higher values of sulfuric acid concentration.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature
VL  - 85
IS  - 13
SP  - 2310
EP  - 2316
DO  - 10.1134/S0036024411130231
ER  - 

@article{
author = "Pejić, Nataša and Vujković, Milica and Maksimović, Jelena and Ivanović, A. and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2011",
abstract = "The non-periodic, periodic and chaotic regimes in the Bray-Liebhafsky (BL) oscillatory reaction observed in a continuously fed well stirred tank reactor (CSTR) under isothermal conditions at various inflow concentrations of the sulfuric acid were experimentally studied. In each series (at any fixed temperature), termination of oscillatory behavior via saddle loop infinite period bifurcation (SNIPER) as well as some kind of the Andronov-Hopf bifurcation is presented. In addition, it was found that an increase of temperature, in different series of experiments resulted in the shift of bifurcation point towards higher values of sulfuric acid concentration.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature",
volume = "85",
number = "13",
pages = "2310-2316",
doi = "10.1134/S0036024411130231"
}

Pejić, N., Vujković, M., Maksimović, J., Ivanović, A., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2011). Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 85(13), 2310-2316.
https://doi.org/10.1134/S0036024411130231

Pejić N, Vujković M, Maksimović J, Ivanović A, Anić S, Čupić Ž, Kolar-Anić L. Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature. in SAR and QSAR in Environmental Research. 2011;85(13):2310-2316.
doi:10.1134/S0036024411130231 .

Pejić, Nataša, Vujković, Milica, Maksimović, Jelena, Ivanović, A., Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature" in SAR and QSAR in Environmental Research, 85, no. 13 (2011):2310-2316,
https://doi.org/10.1134/S0036024411130231 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Maksimović, Jelena
AU  - Ribić, Dragana D.
AU  - Kolar-Anić, Ljiljana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1259
AB  - Dynamic behavior of hydrogen peroxide decomposition catalyzed by iodate and hydrogen ions (the Bray-Liebhafsky reaction), in a continuous stirred tank reactor is investigated. The experimental results are obtained at one operational point in concentration phase space by varying mixed inflow concentrations of the sulfuric acid. The experimental evidences for the onset and termination of oscillatory behavior via the saddle node infinite period bifurcation as well as some kind of the Andronov-Hopf bifurcation are presented. In addition, the possibility of excitability of a stable steady state by thiamine was observed.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Dynamic states of the Bray-Liebhafsky reaction when sulfuric acid is the control parameter
VL  - 83
IS  - 9
SP  - 1490
EP  - 1495
DO  - 10.1134/S0036024409090131
ER  - 

@article{
author = "Pejić, Nataša and Maksimović, Jelena and Ribić, Dragana D. and Kolar-Anić, Ljiljana",
year = "2009",
abstract = "Dynamic behavior of hydrogen peroxide decomposition catalyzed by iodate and hydrogen ions (the Bray-Liebhafsky reaction), in a continuous stirred tank reactor is investigated. The experimental results are obtained at one operational point in concentration phase space by varying mixed inflow concentrations of the sulfuric acid. The experimental evidences for the onset and termination of oscillatory behavior via the saddle node infinite period bifurcation as well as some kind of the Andronov-Hopf bifurcation are presented. In addition, the possibility of excitability of a stable steady state by thiamine was observed.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Dynamic states of the Bray-Liebhafsky reaction when sulfuric acid is the control parameter",
volume = "83",
number = "9",
pages = "1490-1495",
doi = "10.1134/S0036024409090131"
}

Pejić, N., Maksimović, J., Ribić, D. D.,& Kolar-Anić, L.. (2009). Dynamic states of the Bray-Liebhafsky reaction when sulfuric acid is the control parameter. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 83(9), 1490-1495.
https://doi.org/10.1134/S0036024409090131

Pejić N, Maksimović J, Ribić DD, Kolar-Anić L. Dynamic states of the Bray-Liebhafsky reaction when sulfuric acid is the control parameter. in SAR and QSAR in Environmental Research. 2009;83(9):1490-1495.
doi:10.1134/S0036024409090131 .

Pejić, Nataša, Maksimović, Jelena, Ribić, Dragana D., Kolar-Anić, Ljiljana, "Dynamic states of the Bray-Liebhafsky reaction when sulfuric acid is the control parameter" in SAR and QSAR in Environmental Research, 83, no. 9 (2009):1490-1495,
https://doi.org/10.1134/S0036024409090131 . .

TY  - JOUR
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1254
AB  - The kinetic investigations of the malonic acid decomposition (8.00 x 10(-3) mol dm(-3) a parts per thousand currency sign [CH(2)(COOH)(2)](0) a parts per thousand currency sign 4.30 x 10(-2) mol dm(-3)) in the Belousov-Zhabotinsky (BZ) system in the presence of bromate, bromide, sulfuric acid and cerium sulfate, were performed in the isothermal closed well stirred reactor at different temperatures (25.0A degrees C a parts per thousand currency sign T a parts per thousand currency sign 45.0A degrees C). The formal kinetics of the overall BZ reaction, and particularly kinetics in characteristic periods of BZ reaction, based on the analyses of the bromide oscillograms, was accomplished. The evolution as well as the rate constants and the apparent activation energies of the reactions, which exist in the preoscillatory and oscillatory periods, are also successfully calculated by numerical simulations. Simulations are based on the model including the Br(2)O species.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction
VL  - 83
IS  - 9
SP  - 1496
EP  - 1501
DO  - 10.1134/S0036024409090143
ER  - 

@article{
author = "Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2009",
abstract = "The kinetic investigations of the malonic acid decomposition (8.00 x 10(-3) mol dm(-3) a parts per thousand currency sign [CH(2)(COOH)(2)](0) a parts per thousand currency sign 4.30 x 10(-2) mol dm(-3)) in the Belousov-Zhabotinsky (BZ) system in the presence of bromate, bromide, sulfuric acid and cerium sulfate, were performed in the isothermal closed well stirred reactor at different temperatures (25.0A degrees C a parts per thousand currency sign T a parts per thousand currency sign 45.0A degrees C). The formal kinetics of the overall BZ reaction, and particularly kinetics in characteristic periods of BZ reaction, based on the analyses of the bromide oscillograms, was accomplished. The evolution as well as the rate constants and the apparent activation energies of the reactions, which exist in the preoscillatory and oscillatory periods, are also successfully calculated by numerical simulations. Simulations are based on the model including the Br(2)O species.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction",
volume = "83",
number = "9",
pages = "1496-1501",
doi = "10.1134/S0036024409090143"
}

Blagojević, S., Anić, S., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2009). Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 83(9), 1496-1501.
https://doi.org/10.1134/S0036024409090143

Blagojević S, Anić S, Čupić Ž, Pejić N, Kolar-Anić L. Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction. in SAR and QSAR in Environmental Research. 2009;83(9):1496-1501.
doi:10.1134/S0036024409090143 .

Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction" in SAR and QSAR in Environmental Research, 83, no. 9 (2009):1496-1501,
https://doi.org/10.1134/S0036024409090143 . .

TY  - JOUR
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1027
AB  - The influence of the initial malonic acid concentration [MA](0) (8.00 x 10(-3)  lt = [MA](0)  lt = 4.30 x 10(-2) mol dm(-3)) in the presence of bromate (6.20 x 10(-2) mol dm(-3)), bromide (1.50 x 10(-5) mol dm(-3)), sulfuric acid (1.00 mol dm(-3)) and cerium sulfate (2.50 x 10(-3) mol dm(-3)) on the dynamics and the kinetics of the Belousov-Zhabotinsky (BZ) reactions was examined under batch conditions at 30.0 degrees C. The kinetics of the BZ reaction was analyzed by the earlier proposed method convenient for the examinations of the oscillatory reactions. In the defined region of parameters where oscillograms with only large-amplitude relaxation oscillations appeared, the pseudo-first order of the overall malonic acid decomposition with a corresponding rate constant of 2.14 x 10(-2) min(-1) was established. The numerical results on the dynamics and kinetics of the BZ reaction, carried out by the known skeleton model including the Br2O species, were in good agreement with the experimental ones. The already found saddle node infinite period (SNIPER) bifurcation point in transition from a stable quasi-steady state to periodic orbits and vice versa is confirmed by both experimental and numerical investigations of the system under consideration. Namely, the large-amplitude relaxation oscillations with increasing periods between oscillations in approaching the bifurcation points at the beginning and the end of the oscillatory domain, together with excitability of the stable quasi-steady states in their vicinity are obtained.
PB  - Royal Soc Chemistry, Cambridge
T2  - Physical Chemistry Chemical Physics
T1  - Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions
VL  - 10
IS  - 44
SP  - 6658
EP  - 6664
DO  - 10.1039/b804919j
ER  - 

@article{
author = "Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2008",
abstract = "The influence of the initial malonic acid concentration [MA](0) (8.00 x 10(-3)  lt = [MA](0)  lt = 4.30 x 10(-2) mol dm(-3)) in the presence of bromate (6.20 x 10(-2) mol dm(-3)), bromide (1.50 x 10(-5) mol dm(-3)), sulfuric acid (1.00 mol dm(-3)) and cerium sulfate (2.50 x 10(-3) mol dm(-3)) on the dynamics and the kinetics of the Belousov-Zhabotinsky (BZ) reactions was examined under batch conditions at 30.0 degrees C. The kinetics of the BZ reaction was analyzed by the earlier proposed method convenient for the examinations of the oscillatory reactions. In the defined region of parameters where oscillograms with only large-amplitude relaxation oscillations appeared, the pseudo-first order of the overall malonic acid decomposition with a corresponding rate constant of 2.14 x 10(-2) min(-1) was established. The numerical results on the dynamics and kinetics of the BZ reaction, carried out by the known skeleton model including the Br2O species, were in good agreement with the experimental ones. The already found saddle node infinite period (SNIPER) bifurcation point in transition from a stable quasi-steady state to periodic orbits and vice versa is confirmed by both experimental and numerical investigations of the system under consideration. Namely, the large-amplitude relaxation oscillations with increasing periods between oscillations in approaching the bifurcation points at the beginning and the end of the oscillatory domain, together with excitability of the stable quasi-steady states in their vicinity are obtained.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Physical Chemistry Chemical Physics",
title = "Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions",
volume = "10",
number = "44",
pages = "6658-6664",
doi = "10.1039/b804919j"
}

Blagojević, S., Anić, S., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2008). Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions. in Physical Chemistry Chemical Physics
Royal Soc Chemistry, Cambridge., 10(44), 6658-6664.
https://doi.org/10.1039/b804919j

Blagojević S, Anić S, Čupić Ž, Pejić N, Kolar-Anić L. Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions. in Physical Chemistry Chemical Physics. 2008;10(44):6658-6664.
doi:10.1039/b804919j .

Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions" in Physical Chemistry Chemical Physics, 10, no. 44 (2008):6658-6664,
https://doi.org/10.1039/b804919j . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Vukojević, Vladana
AU  - Mijatović, Miroslav D.
AU  - Ćirić, Jasna S.
AU  - Marković, Zoran S.
AU  - Marković, Svetlana D.
AU  - Kolar-Anić, Ljiljana
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/942
AB  - A novel kinetic method for micro-quantitative determinations of morphine (MH) is proposed and validated. The method is based on the potentiometric monitoring of the concentration perturbations of the oscillatory reaction system being in a stable non-equilibrium stationary state close to the bifurcation point between stable and oscillatory state. The response of the Bray-Liebhafsky (BL) oscillatory reaction as a matrix system, to the perturbations by different concentrations of morphine, is followed by a Pt-electrode. The proposed method relies on the linear relationship between maximal potential shift, Delta E-m, and the logarithm of the added morphine amounts in the range of 0.004-0.18 mu mol. Under optimum conditions, the sensitivity of the proposed method (as the limit of detection) is 0.001 mu mol and the method is featured by good precision (R.S.D. = 1.6%) as well as the excellent sample throughput (45 samples h(-1)). In addition to standard solution analysis, this approach was successfully applied for quantitative determination of morphine in a typical pharmaceutical dosage form. Some aspects of the possible mechanism of morphine action on the BL oscillating chemical system are discussed in detail.
PB  - Elsevier Science BV, Amsterdam
T2  - Analytica Chimica Acta
T1  - Kinetic determination of morphine by means of Bray-Liebhafsky oscillatory reaction system using analyte pulse perturbation technique
VL  - 582
IS  - 2
SP  - 367
EP  - 374
DO  - 10.1016/j.aca.2006.09.026
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Anić, Slobodan and Vukojević, Vladana and Mijatović, Miroslav D. and Ćirić, Jasna S. and Marković, Zoran S. and Marković, Svetlana D. and Kolar-Anić, Ljiljana",
year = "2007",
abstract = "A novel kinetic method for micro-quantitative determinations of morphine (MH) is proposed and validated. The method is based on the potentiometric monitoring of the concentration perturbations of the oscillatory reaction system being in a stable non-equilibrium stationary state close to the bifurcation point between stable and oscillatory state. The response of the Bray-Liebhafsky (BL) oscillatory reaction as a matrix system, to the perturbations by different concentrations of morphine, is followed by a Pt-electrode. The proposed method relies on the linear relationship between maximal potential shift, Delta E-m, and the logarithm of the added morphine amounts in the range of 0.004-0.18 mu mol. Under optimum conditions, the sensitivity of the proposed method (as the limit of detection) is 0.001 mu mol and the method is featured by good precision (R.S.D. = 1.6%) as well as the excellent sample throughput (45 samples h(-1)). In addition to standard solution analysis, this approach was successfully applied for quantitative determination of morphine in a typical pharmaceutical dosage form. Some aspects of the possible mechanism of morphine action on the BL oscillating chemical system are discussed in detail.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Analytica Chimica Acta",
title = "Kinetic determination of morphine by means of Bray-Liebhafsky oscillatory reaction system using analyte pulse perturbation technique",
volume = "582",
number = "2",
pages = "367-374",
doi = "10.1016/j.aca.2006.09.026"
}

Pejić, N., Blagojević, S., Anić, S., Vukojević, V., Mijatović, M. D., Ćirić, J. S., Marković, Z. S., Marković, S. D.,& Kolar-Anić, L.. (2007). Kinetic determination of morphine by means of Bray-Liebhafsky oscillatory reaction system using analyte pulse perturbation technique. in Analytica Chimica Acta
Elsevier Science BV, Amsterdam., 582(2), 367-374.
https://doi.org/10.1016/j.aca.2006.09.026

Pejić N, Blagojević S, Anić S, Vukojević V, Mijatović MD, Ćirić JS, Marković ZS, Marković SD, Kolar-Anić L. Kinetic determination of morphine by means of Bray-Liebhafsky oscillatory reaction system using analyte pulse perturbation technique. in Analytica Chimica Acta. 2007;582(2):367-374.
doi:10.1016/j.aca.2006.09.026 .

Pejić, Nataša, Blagojević, Slavica, Anić, Slobodan, Vukojević, Vladana, Mijatović, Miroslav D., Ćirić, Jasna S., Marković, Zoran S., Marković, Svetlana D., Kolar-Anić, Ljiljana, "Kinetic determination of morphine by means of Bray-Liebhafsky oscillatory reaction system using analyte pulse perturbation technique" in Analytica Chimica Acta, 582, no. 2 (2007):367-374,
https://doi.org/10.1016/j.aca.2006.09.026 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Vukelić, Jana
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/895
AB  - A pulse perturbation technique was applied to the Bray-Liebhafsky (BL) oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point, to determine micro-quantitatively 6-O-acetylmorphine (6-O-AM). The proposed method, in optimized reaction conditions ([KIO3](0) = 5.9 x 10(-2) M, [H2SO4](0) = 5.5 x 10(-2) M, and [H2O2](0) = 2.0 x 10(-1) M, j(o) = 2.95 x 10(-2) min(-1), and T = 42.9 degrees C), relied on the linear relationship between maximal potential shift, Delta E-m, caused by perturbation, and the logarithm of the amount of 6-O-acetylmorphine. The method had a rather good sample throughput of 40 samples h(-1) with the sensitivity determined to be 0.9 mu g mL(-1) and the precision RSD = 1.8%. The proposed method was successfully applied to the quantitative determination of 6-O-AM in a real seized street drug sample. The obtained result agrees with those obtained by HPLC. There was no interference from structurally related and associated compounds, such as papaverin, noscapin, and heroin.
PB  - Chemical Soc Japan, Tokyo
T2  - Bulletin of the Chemical Society of Japan
T1  - Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples
VL  - 80
IS  - 10
SP  - 1942
EP  - 1948
DO  - 10.1246/bcsj.80.1942
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Vukelić, Jana and Kolar-Anić, Ljiljana and Anić, Slobodan",
year = "2007",
abstract = "A pulse perturbation technique was applied to the Bray-Liebhafsky (BL) oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point, to determine micro-quantitatively 6-O-acetylmorphine (6-O-AM). The proposed method, in optimized reaction conditions ([KIO3](0) = 5.9 x 10(-2) M, [H2SO4](0) = 5.5 x 10(-2) M, and [H2O2](0) = 2.0 x 10(-1) M, j(o) = 2.95 x 10(-2) min(-1), and T = 42.9 degrees C), relied on the linear relationship between maximal potential shift, Delta E-m, caused by perturbation, and the logarithm of the amount of 6-O-acetylmorphine. The method had a rather good sample throughput of 40 samples h(-1) with the sensitivity determined to be 0.9 mu g mL(-1) and the precision RSD = 1.8%. The proposed method was successfully applied to the quantitative determination of 6-O-AM in a real seized street drug sample. The obtained result agrees with those obtained by HPLC. There was no interference from structurally related and associated compounds, such as papaverin, noscapin, and heroin.",
publisher = "Chemical Soc Japan, Tokyo",
journal = "Bulletin of the Chemical Society of Japan",
title = "Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples",
volume = "80",
number = "10",
pages = "1942-1948",
doi = "10.1246/bcsj.80.1942"
}

Pejić, N., Blagojević, S., Vukelić, J., Kolar-Anić, L.,& Anić, S.. (2007). Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples. in Bulletin of the Chemical Society of Japan
Chemical Soc Japan, Tokyo., 80(10), 1942-1948.
https://doi.org/10.1246/bcsj.80.1942

Pejić N, Blagojević S, Vukelić J, Kolar-Anić L, Anić S. Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples. in Bulletin of the Chemical Society of Japan. 2007;80(10):1942-1948.
doi:10.1246/bcsj.80.1942 .

Pejić, Nataša, Blagojević, Slavica, Vukelić, Jana, Kolar-Anić, Ljiljana, Anić, Slobodan, "Analyte pulse perturbation technique for the determination of 6-O-acetylmorphine in seized street drug samples" in Bulletin of the Chemical Society of Japan, 80, no. 10 (2007):1942-1948,
https://doi.org/10.1246/bcsj.80.1942 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/892
AB  - A simple and reliable method for the determination of ascorbic acid (AA) is proposed and validated. It is based on potentiometric monitoring of the concentration perturbations of an oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point. The response of the Bray-Liebhafsky (BL) oscillatory reaction as a matrix, to the perturbation by different concentrations of AA, is followed by a Pt electrode. The linear relationship between maximal potential shift and the logarithm of the amount of AA is obtained between 0.01 and 1.0 mu mol. The sensitivity of the proposed method (as the limit of detection) is 0.009 mu mol and the method has excellent sample throughput (30 samples per hour). The procedure was used for AA determination in pharmaceutical formulations and urine. The results are in agreement with those obtained using the official method. Some aspects of the possible mechanism of AA action on the BL oscillating chemical system are discussed.
PB  - Springer Heidelberg, Heidelberg
T2  - Analytical and Bioanalytical Chemistry
T1  - Determination of ascorbic acid in pharmaceutical dosage forms and urine by means of an oscillatory reaction system using the pulse perturbation technique
VL  - 389
IS  - 6
SP  - 2009
EP  - 2017
DO  - 10.1007/s00216-007-1585-4
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2007",
abstract = "A simple and reliable method for the determination of ascorbic acid (AA) is proposed and validated. It is based on potentiometric monitoring of the concentration perturbations of an oscillatory reaction system in a stable nonequilibrium stationary state close to the bifurcation point. The response of the Bray-Liebhafsky (BL) oscillatory reaction as a matrix, to the perturbation by different concentrations of AA, is followed by a Pt electrode. The linear relationship between maximal potential shift and the logarithm of the amount of AA is obtained between 0.01 and 1.0 mu mol. The sensitivity of the proposed method (as the limit of detection) is 0.009 mu mol and the method has excellent sample throughput (30 samples per hour). The procedure was used for AA determination in pharmaceutical formulations and urine. The results are in agreement with those obtained using the official method. Some aspects of the possible mechanism of AA action on the BL oscillating chemical system are discussed.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Analytical and Bioanalytical Chemistry",
title = "Determination of ascorbic acid in pharmaceutical dosage forms and urine by means of an oscillatory reaction system using the pulse perturbation technique",
volume = "389",
number = "6",
pages = "2009-2017",
doi = "10.1007/s00216-007-1585-4"
}

Pejić, N., Blagojević, S., Anić, S.,& Kolar-Anić, L.. (2007). Determination of ascorbic acid in pharmaceutical dosage forms and urine by means of an oscillatory reaction system using the pulse perturbation technique. in Analytical and Bioanalytical Chemistry
Springer Heidelberg, Heidelberg., 389(6), 2009-2017.
https://doi.org/10.1007/s00216-007-1585-4

Pejić N, Blagojević S, Anić S, Kolar-Anić L. Determination of ascorbic acid in pharmaceutical dosage forms and urine by means of an oscillatory reaction system using the pulse perturbation technique. in Analytical and Bioanalytical Chemistry. 2007;389(6):2009-2017.
doi:10.1007/s00216-007-1585-4 .

Pejić, Nataša, Blagojević, Slavica, Anić, Slobodan, Kolar-Anić, Ljiljana, "Determination of ascorbic acid in pharmaceutical dosage forms and urine by means of an oscillatory reaction system using the pulse perturbation technique" in Analytical and Bioanalytical Chemistry, 389, no. 6 (2007):2009-2017,
https://doi.org/10.1007/s00216-007-1585-4 . .

TY  - JOUR
AU  - Kolar-Anić, Ljiljana
AU  - Blagojević, Slavica
AU  - Pejić, Nataša
AU  - Begović, Nebojša
AU  - Blagojević, Stevan
AU  - Anić, Slobodan
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/888
AB  - Some new experimental evidence of complex irregular oscillations in the Belousov-Zhabotinsky reaction realized in a batch reactor is presented. The results were obtained under relatively low cerium and malonic acid concentrations. One-dimensional maps were used for general discussion, and particularly, for the influence of noise on the evolution of the oscillations.
AB  - Daju se novi eksperimentalni rezultati o kompleksnim neregularnim oscilacijama BŽ sistema ostvarenog u zatvorenom reaktoru, u uslovima relativno niske koncentracije cerijuma i malonske kiseline. Jednodimenzionalne mape su korišćene za generalnu diskusiju rezultata, a posebno za uticaj šuma na oscilatornu evoluciju.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - New evidence of transient complex oscillations in a closed, well-stirred belousov-zhabotinsky system
T1  - Novozabeležene tranzijentne kompleksne oscilacije u zatvorenom belousov-žabotinski reakcionom sistemu sa dobrim mešanjem
VL  - 71
IS  - 6
SP  - 605
EP  - 612
DO  - 10.2298/JSC0606605K
ER  - 

@article{
author = "Kolar-Anić, Ljiljana and Blagojević, Slavica and Pejić, Nataša and Begović, Nebojša and Blagojević, Stevan and Anić, Slobodan",
year = "2006",
abstract = "Some new experimental evidence of complex irregular oscillations in the Belousov-Zhabotinsky reaction realized in a batch reactor is presented. The results were obtained under relatively low cerium and malonic acid concentrations. One-dimensional maps were used for general discussion, and particularly, for the influence of noise on the evolution of the oscillations., Daju se novi eksperimentalni rezultati o kompleksnim neregularnim oscilacijama BŽ sistema ostvarenog u zatvorenom reaktoru, u uslovima relativno niske koncentracije cerijuma i malonske kiseline. Jednodimenzionalne mape su korišćene za generalnu diskusiju rezultata, a posebno za uticaj šuma na oscilatornu evoluciju.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "New evidence of transient complex oscillations in a closed, well-stirred belousov-zhabotinsky system, Novozabeležene tranzijentne kompleksne oscilacije u zatvorenom belousov-žabotinski reakcionom sistemu sa dobrim mešanjem",
volume = "71",
number = "6",
pages = "605-612",
doi = "10.2298/JSC0606605K"
}

Kolar-Anić, L., Blagojević, S., Pejić, N., Begović, N., Blagojević, S.,& Anić, S.. (2006). New evidence of transient complex oscillations in a closed, well-stirred belousov-zhabotinsky system. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 71(6), 605-612.
https://doi.org/10.2298/JSC0606605K

Kolar-Anić L, Blagojević S, Pejić N, Begović N, Blagojević S, Anić S. New evidence of transient complex oscillations in a closed, well-stirred belousov-zhabotinsky system. in Journal of the Serbian Chemical Society. 2006;71(6):605-612.
doi:10.2298/JSC0606605K .

Kolar-Anić, Ljiljana, Blagojević, Slavica, Pejić, Nataša, Begović, Nebojša, Blagojević, Stevan, Anić, Slobodan, "New evidence of transient complex oscillations in a closed, well-stirred belousov-zhabotinsky system" in Journal of the Serbian Chemical Society, 71, no. 6 (2006):605-612,
https://doi.org/10.2298/JSC0606605K . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
AU  - Stanisavljev, Dragomir
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/861
AB  - A new procedure for kinetic determination of paracetamol in pharmaceuticals is proposed. The method is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system being in a stable non-equilibrium stationary state close to the bifurcation point. In the case considered as the matrix system, the Bray-Liebhafsky oscillatory reaction is used. The response of the matrix system to the perturbations by different concentrations of paracetamol is followed by a Pt-electrode. Proposed method relies on the linear relationship between maximal potential shift, Delta E-m, and the logarithm of added paracetamol amounts. It is obtained in optimized experimental conditions for variable amounts of paracetamol in the range 0.0085 and 1.5 mu mol. The sensitivity and precision of proposed method were quite good (0.0027 mu mol as the limit of detection and 2.4% as R.S.D.). Some aspects of possible chemical interactions between paracetamol and matrix are discussed. Applicability of the proposed method to the direct determination of paracetamol in pharmaceutical formulations was demonstrated.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique
VL  - 41
IS  - 2
SP  - 610
EP  - 615
DO  - 10.1016/j.jpba.2005.11.043
ER  - 

@article{
author = "Pejić, Nataša and Kolar-Anić, Ljiljana and Anić, Slobodan and Stanisavljev, Dragomir",
year = "2006",
abstract = "A new procedure for kinetic determination of paracetamol in pharmaceuticals is proposed. The method is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system being in a stable non-equilibrium stationary state close to the bifurcation point. In the case considered as the matrix system, the Bray-Liebhafsky oscillatory reaction is used. The response of the matrix system to the perturbations by different concentrations of paracetamol is followed by a Pt-electrode. Proposed method relies on the linear relationship between maximal potential shift, Delta E-m, and the logarithm of added paracetamol amounts. It is obtained in optimized experimental conditions for variable amounts of paracetamol in the range 0.0085 and 1.5 mu mol. The sensitivity and precision of proposed method were quite good (0.0027 mu mol as the limit of detection and 2.4% as R.S.D.). Some aspects of possible chemical interactions between paracetamol and matrix are discussed. Applicability of the proposed method to the direct determination of paracetamol in pharmaceutical formulations was demonstrated.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique",
volume = "41",
number = "2",
pages = "610-615",
doi = "10.1016/j.jpba.2005.11.043"
}

Pejić, N., Kolar-Anić, L., Anić, S.,& Stanisavljev, D.. (2006). Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science BV, Amsterdam., 41(2), 610-615.
https://doi.org/10.1016/j.jpba.2005.11.043

Pejić N, Kolar-Anić L, Anić S, Stanisavljev D. Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique. in Journal of Pharmaceutical and Biomedical Analysis. 2006;41(2):610-615.
doi:10.1016/j.jpba.2005.11.043 .

Pejić, Nataša, Kolar-Anić, Ljiljana, Anić, Slobodan, Stanisavljev, Dragomir, "Determination of paracetamol in pure and pharmaceutical dosage forms by pulse perturbation technique" in Journal of Pharmaceutical and Biomedical Analysis, 41, no. 2 (2006):610-615,
https://doi.org/10.1016/j.jpba.2005.11.043 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Vukojević, Vladana
AU  - Kolar-Anić, Ljiljana
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/639
AB  - A simple and reliable kinetic method for the determination of hesperidin (Hesp) is developed. It is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system which is in a stable non-equilibrium stationary state close to the bifurcation point. The Bray-Liebhafsky oscillatory reaction is used as the matrix system. The response of the matrix to perturbations by different concentrations of Hesp is followed by using a Pt electrode. A linear relationship between maximal potential shift and the logarithm of Hesp concentrations is obtained between 7.5 and 599.4 mu g mL(-1). The limit of detection is 0.65 mu g mL(-1). The described procedure has been successfully applied to the determination of Hesp from different sources (capsules, industrial and hand-squeezed orange juice, and white wine).
PB  - Springer Heidelberg, Heidelberg
T2  - Analytical and Bioanalytical Chemistry
T1  - Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system
VL  - 381
IS  - 3
SP  - 775
EP  - 780
DO  - 10.1007/s00216-004-2913-6
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Anić, Slobodan and Vukojević, Vladana and Kolar-Anić, Ljiljana",
year = "2005",
abstract = "A simple and reliable kinetic method for the determination of hesperidin (Hesp) is developed. It is based on potentiometric monitoring of the concentration perturbations of the matrix reaction system which is in a stable non-equilibrium stationary state close to the bifurcation point. The Bray-Liebhafsky oscillatory reaction is used as the matrix system. The response of the matrix to perturbations by different concentrations of Hesp is followed by using a Pt electrode. A linear relationship between maximal potential shift and the logarithm of Hesp concentrations is obtained between 7.5 and 599.4 mu g mL(-1). The limit of detection is 0.65 mu g mL(-1). The described procedure has been successfully applied to the determination of Hesp from different sources (capsules, industrial and hand-squeezed orange juice, and white wine).",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Analytical and Bioanalytical Chemistry",
title = "Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system",
volume = "381",
number = "3",
pages = "775-780",
doi = "10.1007/s00216-004-2913-6"
}

Pejić, N., Blagojević, S., Anić, S., Vukojević, V.,& Kolar-Anić, L.. (2005). Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system. in Analytical and Bioanalytical Chemistry
Springer Heidelberg, Heidelberg., 381(3), 775-780.
https://doi.org/10.1007/s00216-004-2913-6

Pejić N, Blagojević S, Anić S, Vukojević V, Kolar-Anić L. Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system. in Analytical and Bioanalytical Chemistry. 2005;381(3):775-780.
doi:10.1007/s00216-004-2913-6 .

Pejić, Nataša, Blagojević, Slavica, Anić, Slobodan, Vukojević, Vladana, Kolar-Anić, Ljiljana, "Microquantitative determination of hesperidin by pulse perturbation of the oscillatory reaction system" in Analytical and Bioanalytical Chemistry, 381, no. 3 (2005):775-780,
https://doi.org/10.1007/s00216-004-2913-6 . .

TY  - JOUR
AU  - Milošević, M
AU  - Pejić, Nataša
AU  - Čupić, Željko
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/575
AB  - Macroporous cross-linked copolymer of 4-vinylpyridine and 25% (4: 1) divinylbenzene is analyzed under open conditions, that is in a continuous well-stirred tank reactor (CSTR). With this aim the appropriate bifurcation diagram is found and the behavior of the system with and without polymer in the vicinity of the bifurcation point is used for the polymer examinations. Two different granulations of polymer are considered. Moreover, some physicochemical characteristics of the polymer, such as specific surface area, skeletal and particle density, are determined.
PB  - Trans Tech Publications Ltd, Durnten-Zurich
T2  - Current Research in Advanced Materials and Processes
T1  - Examinations of cross-linked polyvinylpyridine in open reactor
VL  - 494
SP  - 369
EP  - 374
DO  - 10.4028/www.scientific.net/MSF.494.369
ER  - 

@article{
author = "Milošević, M and Pejić, Nataša and Čupić, Željko and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2005",
abstract = "Macroporous cross-linked copolymer of 4-vinylpyridine and 25% (4: 1) divinylbenzene is analyzed under open conditions, that is in a continuous well-stirred tank reactor (CSTR). With this aim the appropriate bifurcation diagram is found and the behavior of the system with and without polymer in the vicinity of the bifurcation point is used for the polymer examinations. Two different granulations of polymer are considered. Moreover, some physicochemical characteristics of the polymer, such as specific surface area, skeletal and particle density, are determined.",
publisher = "Trans Tech Publications Ltd, Durnten-Zurich",
journal = "Current Research in Advanced Materials and Processes",
title = "Examinations of cross-linked polyvinylpyridine in open reactor",
volume = "494",
pages = "369-374",
doi = "10.4028/www.scientific.net/MSF.494.369"
}

Milošević, M., Pejić, N., Čupić, Ž., Anić, S.,& Kolar-Anić, L.. (2005). Examinations of cross-linked polyvinylpyridine in open reactor. in Current Research in Advanced Materials and Processes
Trans Tech Publications Ltd, Durnten-Zurich., 494, 369-374.
https://doi.org/10.4028/www.scientific.net/MSF.494.369

Milošević M, Pejić N, Čupić Ž, Anić S, Kolar-Anić L. Examinations of cross-linked polyvinylpyridine in open reactor. in Current Research in Advanced Materials and Processes. 2005;494:369-374.
doi:10.4028/www.scientific.net/MSF.494.369 .

Milošević, M, Pejić, Nataša, Čupić, Željko, Anić, Slobodan, Kolar-Anić, Ljiljana, "Examinations of cross-linked polyvinylpyridine in open reactor" in Current Research in Advanced Materials and Processes, 494 (2005):369-374,
https://doi.org/10.4028/www.scientific.net/MSF.494.369 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Anić, Slobodan
AU  - Kuntić, Vesna
AU  - Vukojević, Vladana
AU  - Kolar-Anić, Ljiljana
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/426
AB  - A kinetic method is described for the microquantitative (microconcentration/microvolume) determination of rutin based on potentiometric monitoring of the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory reaction being in a non-equilibrium stationary state close to a bifurcation point. The experiments are carried out in an open reactor. The response of the matrix system to perturbations by different concentrations of rutin ethanolic solutions is followed by a Pt-electrode. In the concentration range between 7.8x10(-8) mol dm(-3) and 9.1x10(-6) mol dm(-3), we found a linear dependence of the maximal potential shift, DeltaE(m), on the logarithm of the rutin concentrations. The unknown concentrations can be determined from the calibration curve up to an accuracy of +/-5%. The detection limit is 3.6x10(-8) mol dm(-3). The amount of required sample can be as small as 10 muL.
PB  - Springer-Verlag Wien, Vienna
T2  - Microchimica Acta
T1  - Kinetic determination of microquantities of rutin by perturbation of the Bray-Liebhafsky oscillatory reaction in an open system
VL  - 143
IS  - 4
SP  - 261
EP  - 267
DO  - 10.1007/s00604-003-0071-8
ER  - 

@article{
author = "Pejić, Nataša and Anić, Slobodan and Kuntić, Vesna and Vukojević, Vladana and Kolar-Anić, Ljiljana",
year = "2003",
abstract = "A kinetic method is described for the microquantitative (microconcentration/microvolume) determination of rutin based on potentiometric monitoring of the concentration perturbations of the Bray-Liebhafsky (BL) oscillatory reaction being in a non-equilibrium stationary state close to a bifurcation point. The experiments are carried out in an open reactor. The response of the matrix system to perturbations by different concentrations of rutin ethanolic solutions is followed by a Pt-electrode. In the concentration range between 7.8x10(-8) mol dm(-3) and 9.1x10(-6) mol dm(-3), we found a linear dependence of the maximal potential shift, DeltaE(m), on the logarithm of the rutin concentrations. The unknown concentrations can be determined from the calibration curve up to an accuracy of +/-5%. The detection limit is 3.6x10(-8) mol dm(-3). The amount of required sample can be as small as 10 muL.",
publisher = "Springer-Verlag Wien, Vienna",
journal = "Microchimica Acta",
title = "Kinetic determination of microquantities of rutin by perturbation of the Bray-Liebhafsky oscillatory reaction in an open system",
volume = "143",
number = "4",
pages = "261-267",
doi = "10.1007/s00604-003-0071-8"
}

Pejić, N., Anić, S., Kuntić, V., Vukojević, V.,& Kolar-Anić, L.. (2003). Kinetic determination of microquantities of rutin by perturbation of the Bray-Liebhafsky oscillatory reaction in an open system. in Microchimica Acta
Springer-Verlag Wien, Vienna., 143(4), 261-267.
https://doi.org/10.1007/s00604-003-0071-8

Pejić N, Anić S, Kuntić V, Vukojević V, Kolar-Anić L. Kinetic determination of microquantities of rutin by perturbation of the Bray-Liebhafsky oscillatory reaction in an open system. in Microchimica Acta. 2003;143(4):261-267.
doi:10.1007/s00604-003-0071-8 .

Pejić, Nataša, Anić, Slobodan, Kuntić, Vesna, Vukojević, Vladana, Kolar-Anić, Ljiljana, "Kinetic determination of microquantities of rutin by perturbation of the Bray-Liebhafsky oscillatory reaction in an open system" in Microchimica Acta, 143, no. 4 (2003):261-267,
https://doi.org/10.1007/s00604-003-0071-8 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Čupić, Željko
AU  - Anić, Slobodan
AU  - Vukojević, Vladana
AU  - Kolar-Anić, Ljiljana
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/301
AB  - The Bray-Liebhafsky (BL) oscillatory reaction, as a reaction where hydrogen peroxide decomposes into the water and oxygen in the presence of iodate and hydrogen ions through a complex mechanism involving a number of intermediates, such as I-, I2, HIO and HIO2, was used as the matrix for analysis of kinetic properties of the catalysts for hydrogen peroxide decomposition. The examined catalysts were enzyme peroxidase (isolated from the horseradish root) and polymeric catalyst (acid form of poly-4-vynil-pyridine functionalized by fericsulfate). The change of kinetic state of the system caused by the presence of added catalyst is reflected in the form of oscillograms, in the time elapsed from the beginning of the reaction to the first oscillation, in the time elapsed from the beginning of the reaction to the end of oscillatory evolution, the number of oscillations, the average period between oscillations and its frequency. Since all these kinetic properties depend on the added amounts of both mentioned catalysts in a complex but analogous manner, a similar reaction mechanism could be expected in both cases.
AB  - Braj-Liebhafski (BL) oscilatorna reakcija, kao reakcija u kojoj se vodonik-peroksid, u prisustvu jodata i vodoničnih jona, razlaže na vodu i kiseonik, po kompleksnom mehanizmu koji uključuje nastanak brojnih intermedijera kao što su I-, I2, HIO i HIO2 je korišćena kao matrica za analizu kinetičkih osobina katalizatora za razlaganje vodonik-peroksida. Ispitivani katalizatori su peroksidaza izolovana iz korena rena i sintetički polimer (kiseli oblik poli-4-vinil-piridina funkcionalizovanog sa ferisulfatom). Promene kinetičkog stanja sistema izazvane prisustvom dodatih količina katalizatora se reflektuju na formu oscilograma, na vreme proteklo od početka reakcije do pojave prve oscilacije, na vreme proteklo od početka reakcije do kraja oscilatorne evolucije, broj oscilacija, srednjeg perioda oscilovanja i njihovu frekvenciju. Kako sva ova kinetička svojstva zavise od dodatih količina katalizatora na kompleksan ali analogan način, sličan reakcioni mehanizam se može očekivati u oba slučaja.
PB  - Međunarodni Institut za nauku o sinterovanju, Beograd
T2  - Science of Sintering
T1  - The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide
VL  - 33
IS  - 2
SP  - 107
EP  - 115
UR  - https://hdl.handle.net/21.15107/rcub_farfar_301
ER  - 

@article{
author = "Pejić, Nataša and Čupić, Željko and Anić, Slobodan and Vukojević, Vladana and Kolar-Anić, Ljiljana",
year = "2001",
abstract = "The Bray-Liebhafsky (BL) oscillatory reaction, as a reaction where hydrogen peroxide decomposes into the water and oxygen in the presence of iodate and hydrogen ions through a complex mechanism involving a number of intermediates, such as I-, I2, HIO and HIO2, was used as the matrix for analysis of kinetic properties of the catalysts for hydrogen peroxide decomposition. The examined catalysts were enzyme peroxidase (isolated from the horseradish root) and polymeric catalyst (acid form of poly-4-vynil-pyridine functionalized by fericsulfate). The change of kinetic state of the system caused by the presence of added catalyst is reflected in the form of oscillograms, in the time elapsed from the beginning of the reaction to the first oscillation, in the time elapsed from the beginning of the reaction to the end of oscillatory evolution, the number of oscillations, the average period between oscillations and its frequency. Since all these kinetic properties depend on the added amounts of both mentioned catalysts in a complex but analogous manner, a similar reaction mechanism could be expected in both cases., Braj-Liebhafski (BL) oscilatorna reakcija, kao reakcija u kojoj se vodonik-peroksid, u prisustvu jodata i vodoničnih jona, razlaže na vodu i kiseonik, po kompleksnom mehanizmu koji uključuje nastanak brojnih intermedijera kao što su I-, I2, HIO i HIO2 je korišćena kao matrica za analizu kinetičkih osobina katalizatora za razlaganje vodonik-peroksida. Ispitivani katalizatori su peroksidaza izolovana iz korena rena i sintetički polimer (kiseli oblik poli-4-vinil-piridina funkcionalizovanog sa ferisulfatom). Promene kinetičkog stanja sistema izazvane prisustvom dodatih količina katalizatora se reflektuju na formu oscilograma, na vreme proteklo od početka reakcije do pojave prve oscilacije, na vreme proteklo od početka reakcije do kraja oscilatorne evolucije, broj oscilacija, srednjeg perioda oscilovanja i njihovu frekvenciju. Kako sva ova kinetička svojstva zavise od dodatih količina katalizatora na kompleksan ali analogan način, sličan reakcioni mehanizam se može očekivati u oba slučaja.",
publisher = "Međunarodni Institut za nauku o sinterovanju, Beograd",
journal = "Science of Sintering",
title = "The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide",
volume = "33",
number = "2",
pages = "107-115",
url = "https://hdl.handle.net/21.15107/rcub_farfar_301"
}

Pejić, N., Čupić, Ž., Anić, S., Vukojević, V.,& Kolar-Anić, L.. (2001). The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide. in Science of Sintering
Međunarodni Institut za nauku o sinterovanju, Beograd., 33(2), 107-115.
https://hdl.handle.net/21.15107/rcub_farfar_301

Pejić N, Čupić Ž, Anić S, Vukojević V, Kolar-Anić L. The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide. in Science of Sintering. 2001;33(2):107-115.
https://hdl.handle.net/21.15107/rcub_farfar_301 .

Pejić, Nataša, Čupić, Željko, Anić, Slobodan, Vukojević, Vladana, Kolar-Anić, Ljiljana, "The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide" in Science of Sintering, 33, no. 2 (2001):107-115,
https://hdl.handle.net/21.15107/rcub_farfar_301 .