TY  - JOUR
AU  - Negrojević, Luka
AU  - Lončar, Aleksandar
AU  - Maksimović, Jelena
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
AU  - Pejić, Nataša
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4022
AB  - A kinetic method for the determination of l-tyrosine (Tyr) by analyte pulse perturbation, caused by different amounts of Tyr, in the Bray–Liebhafsky (BL) oscillatory reaction realized in a continuous-flow stirred tank reactor, is proposed. For such purposes, the BL oscillating reaction was kept in a stable non-equilibrium stationary state close to the bifurcation point and was used as the matrix reaction system. Under optimum reaction conditions, the linear relationship between the kinetic parameters, Δτ2 (the period between first two oscillations that appear after applied perturbation) as well as τend (the time elapsed between the perturbation of the BL reaction by Tyr and the termination of the oscillatory phase) and the Tyr concentrations is obtained over the ranges 1.1 × 10− 6 − 9.2 × 10− 6 mol L− 1 and 1.1 × 10− 6 − 1.4 × 10− 5 mol L− 1, with the limit of detections of 6.6 × 10− 7 mol L− 1 and 6.4 × 10− 7 mol L− 1. The described method that relies on a simple instrumental set-up, has been successfully applied to the determination of Tyr in a dietary supplement. Some aspects of the possible mechanism of Tyr action on the BL oscillator are discussed.
PB  - Springer Science and Business Media B.V.
T2  - Reaction Kinetics, Mechanisms and Catalysis
T1  - Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine
DO  - 10.1007/s11144-021-02130-5
ER  - 

@article{
author = "Negrojević, Luka and Lončar, Aleksandar and Maksimović, Jelena and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana and Pejić, Nataša",
year = "2022",
abstract = "A kinetic method for the determination of l-tyrosine (Tyr) by analyte pulse perturbation, caused by different amounts of Tyr, in the Bray–Liebhafsky (BL) oscillatory reaction realized in a continuous-flow stirred tank reactor, is proposed. For such purposes, the BL oscillating reaction was kept in a stable non-equilibrium stationary state close to the bifurcation point and was used as the matrix reaction system. Under optimum reaction conditions, the linear relationship between the kinetic parameters, Δτ2 (the period between first two oscillations that appear after applied perturbation) as well as τend (the time elapsed between the perturbation of the BL reaction by Tyr and the termination of the oscillatory phase) and the Tyr concentrations is obtained over the ranges 1.1 × 10− 6 − 9.2 × 10− 6 mol L− 1 and 1.1 × 10− 6 − 1.4 × 10− 5 mol L− 1, with the limit of detections of 6.6 × 10− 7 mol L− 1 and 6.4 × 10− 7 mol L− 1. The described method that relies on a simple instrumental set-up, has been successfully applied to the determination of Tyr in a dietary supplement. Some aspects of the possible mechanism of Tyr action on the BL oscillator are discussed.",
publisher = "Springer Science and Business Media B.V.",
journal = "Reaction Kinetics, Mechanisms and Catalysis",
title = "Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine",
doi = "10.1007/s11144-021-02130-5"
}

Negrojević, L., Lončar, A., Maksimović, J., Anić, S., Čupić, Ž., Kolar-Anić, L.,& Pejić, N.. (2022). Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine. in Reaction Kinetics, Mechanisms and Catalysis
Springer Science and Business Media B.V...
https://doi.org/10.1007/s11144-021-02130-5

Negrojević L, Lončar A, Maksimović J, Anić S, Čupić Ž, Kolar-Anić L, Pejić N. Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine. in Reaction Kinetics, Mechanisms and Catalysis. 2022;.
doi:10.1007/s11144-021-02130-5 .

Negrojević, Luka, Lončar, Aleksandar, Maksimović, Jelena, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, Pejić, Nataša, "Bray–Liebhafsky oscillatory reaction in a continuous-flow stirred tank reactor as the matrix system for determination of tyrosine" in Reaction Kinetics, Mechanisms and Catalysis (2022),
https://doi.org/10.1007/s11144-021-02130-5 . .

TY  - JOUR
AU  - Macesić, Stevan
AU  - Čupić, Željko
AU  - Ivanović-Sasić, Ana
AU  - Anić, Slobodan
AU  - Radenković, Mirjana
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3203
AB  - In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained system's dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Bifurcation analysis: a tool for determining model parameters of the considered process
VL  - 123
IS  - 1
SP  - 31
EP  - 45
DO  - 10.1007/s11144-017-1324-6
ER  - 

@article{
author = "Macesić, Stevan and Čupić, Željko and Ivanović-Sasić, Ana and Anić, Slobodan and Radenković, Mirjana and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2018",
abstract = "In this paper, we intend to show the importance of the bifurcation analysis in understanding of an oscillatory process. Hence, we use the bifurcation diagram of the Bray-Liebhafsky reaction performed in continuous well-stirred tank reactor under controlled temperature variations for the determination of the activation energies as well as rate constants of particular steps appearing in the kinetic model of oscillatory reaction mechanism. This approach has led us to the development of general procedure for treatment of experimentally obtained data and extracting kinetic parameters from them, which was very important considering that some rate constants of the already proposed model could not be determined experimentally and have to be fitted (or guessed). Also, the proposed approach has the potential to inspire the refinement of already proposed models and the development of a new one that will be able to reproduce experimentally obtained system's dynamical features more successfully. In particular, the dynamic states of the Bray-Liebhafsky oscillatory reaction have been analyzed experimentally and numerically using already proposed model together with qualitative and quantitative analysis of bifurcation diagrams in both cases.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Bifurcation analysis: a tool for determining model parameters of the considered process",
volume = "123",
number = "1",
pages = "31-45",
doi = "10.1007/s11144-017-1324-6"
}

Macesić, S., Čupić, Ž., Ivanović-Sasić, A., Anić, S., Radenković, M., Pejić, N.,& Kolar-Anić, L.. (2018). Bifurcation analysis: a tool for determining model parameters of the considered process. in Records of Natural Products
Springer, Dordrecht., 123(1), 31-45.
https://doi.org/10.1007/s11144-017-1324-6

Macesić S, Čupić Ž, Ivanović-Sasić A, Anić S, Radenković M, Pejić N, Kolar-Anić L. Bifurcation analysis: a tool for determining model parameters of the considered process. in Records of Natural Products. 2018;123(1):31-45.
doi:10.1007/s11144-017-1324-6 .

Macesić, Stevan, Čupić, Željko, Ivanović-Sasić, Ana, Anić, Slobodan, Radenković, Mirjana, Pejić, Nataša, Kolar-Anić, Ljiljana, "Bifurcation analysis: a tool for determining model parameters of the considered process" in Records of Natural Products, 123, no. 1 (2018):31-45,
https://doi.org/10.1007/s11144-017-1324-6 . .

TY  - JOUR
AU  - Cervellati, Rinaldo
AU  - Greco, Emanuela
AU  - Blagojević, Slavica
AU  - Blagojević, Stevan
AU  - Anić, Slobodan
AU  - Čupić, Željko
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3202
AB  - The system KSCN-H2O2-CuSO4-NaOH, also known as the OrbA n-Epstein oscillatory reaction, is exposed to external perturbations by several phenolic compounds: catechol, resorcinol, hydroquinone, 2,5-dihydroxybenzoic acid, 2,6-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, caffeic acid, and ferulic acid. As a result of the performed perturbation in most examined cases, oscillations have been inhibited for some characteristic time, and resumed afterwards. The evaluated inhibition time is typical for each substance and strongly dependent on its concentration. The chemical mechanism of the interaction between the OrbA n-Epstein system and phenolic compounds is briefly discussed. Numerical simulations are performed using the original OrbA n-Epstein model with 30 reactions, extended by three reactions describing the interaction with inhibitory substances. The rate constants of three added reactions are adjusted to fit experimental inhibition times, and compared among used compounds. The observed effects are discussed further in relation with the bond dissociation enthalpy theory. Unlike other tested compounds, 2,5-dihydroxybenzoic acid remains off from predicted order of activity.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Experimental and mechanistic study of the inhibitory effects by phenolics on the oscillations of the OrbA n-Epstein Reaction
VL  - 123
IS  - 1
SP  - 125
EP  - 139
DO  - 10.1007/s11144-017-1306-8
ER  - 

@article{
author = "Cervellati, Rinaldo and Greco, Emanuela and Blagojević, Slavica and Blagojević, Stevan and Anić, Slobodan and Čupić, Željko",
year = "2018",
abstract = "The system KSCN-H2O2-CuSO4-NaOH, also known as the OrbA n-Epstein oscillatory reaction, is exposed to external perturbations by several phenolic compounds: catechol, resorcinol, hydroquinone, 2,5-dihydroxybenzoic acid, 2,6-dihydroxybenzoic acid, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, 3,4-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, caffeic acid, and ferulic acid. As a result of the performed perturbation in most examined cases, oscillations have been inhibited for some characteristic time, and resumed afterwards. The evaluated inhibition time is typical for each substance and strongly dependent on its concentration. The chemical mechanism of the interaction between the OrbA n-Epstein system and phenolic compounds is briefly discussed. Numerical simulations are performed using the original OrbA n-Epstein model with 30 reactions, extended by three reactions describing the interaction with inhibitory substances. The rate constants of three added reactions are adjusted to fit experimental inhibition times, and compared among used compounds. The observed effects are discussed further in relation with the bond dissociation enthalpy theory. Unlike other tested compounds, 2,5-dihydroxybenzoic acid remains off from predicted order of activity.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Experimental and mechanistic study of the inhibitory effects by phenolics on the oscillations of the OrbA n-Epstein Reaction",
volume = "123",
number = "1",
pages = "125-139",
doi = "10.1007/s11144-017-1306-8"
}

Cervellati, R., Greco, E., Blagojević, S., Blagojević, S., Anić, S.,& Čupić, Ž.. (2018). Experimental and mechanistic study of the inhibitory effects by phenolics on the oscillations of the OrbA n-Epstein Reaction. in Records of Natural Products
Springer, Dordrecht., 123(1), 125-139.
https://doi.org/10.1007/s11144-017-1306-8

Cervellati R, Greco E, Blagojević S, Blagojević S, Anić S, Čupić Ž. Experimental and mechanistic study of the inhibitory effects by phenolics on the oscillations of the OrbA n-Epstein Reaction. in Records of Natural Products. 2018;123(1):125-139.
doi:10.1007/s11144-017-1306-8 .

Cervellati, Rinaldo, Greco, Emanuela, Blagojević, Slavica, Blagojević, Stevan, Anić, Slobodan, Čupić, Željko, "Experimental and mechanistic study of the inhibitory effects by phenolics on the oscillations of the OrbA n-Epstein Reaction" in Records of Natural Products, 123, no. 1 (2018):125-139,
https://doi.org/10.1007/s11144-017-1306-8 . .

TY  - JOUR
AU  - Čupić, Željko
AU  - Ivanović-Sasic, Ana
AU  - Blagojevic, Stevan
AU  - Blagojević, Slavica
AU  - Kolar-Anić, Ljiljana
AU  - Anić, Slobodan
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2545
AB  - By numerically simulated Bray-Liebhafsky (BL) reaction under a continuously fed well stirred tank reactor (CSTR) conditions, we discussed the attractors and Poincar, 1D maps with respect to flow rate as the control parameter. The new technique of the return maps from transient trajectories over the slow manifold is developed and applied in order to explore its multilayered structure related to dynamical states (periodic and aperiodic -chaotic oscillating modes) of the system. Kinetic relations underlying the slow manifold structure are briefly discussed.
PB  - Springer, Dordrecht
T2  - Records of Natural Products
T1  - Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model
VL  - 118
IS  - 1
SP  - 27
EP  - 38
DO  - 10.1007/s11144-016-0998-5
ER  - 

@article{
author = "Čupić, Željko and Ivanović-Sasic, Ana and Blagojevic, Stevan and Blagojević, Slavica and Kolar-Anić, Ljiljana and Anić, Slobodan",
year = "2016",
abstract = "By numerically simulated Bray-Liebhafsky (BL) reaction under a continuously fed well stirred tank reactor (CSTR) conditions, we discussed the attractors and Poincar, 1D maps with respect to flow rate as the control parameter. The new technique of the return maps from transient trajectories over the slow manifold is developed and applied in order to explore its multilayered structure related to dynamical states (periodic and aperiodic -chaotic oscillating modes) of the system. Kinetic relations underlying the slow manifold structure are briefly discussed.",
publisher = "Springer, Dordrecht",
journal = "Records of Natural Products",
title = "Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model",
volume = "118",
number = "1",
pages = "27-38",
doi = "10.1007/s11144-016-0998-5"
}

Čupić, Ž., Ivanović-Sasic, A., Blagojevic, S., Blagojević, S., Kolar-Anić, L.,& Anić, S.. (2016). Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model. in Records of Natural Products
Springer, Dordrecht., 118(1), 27-38.
https://doi.org/10.1007/s11144-016-0998-5

Čupić Ž, Ivanović-Sasic A, Blagojevic S, Blagojević S, Kolar-Anić L, Anić S. Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model. in Records of Natural Products. 2016;118(1):27-38.
doi:10.1007/s11144-016-0998-5 .

Čupić, Željko, Ivanović-Sasic, Ana, Blagojevic, Stevan, Blagojević, Slavica, Kolar-Anić, Ljiljana, Anić, Slobodan, "Return map analysis of the highly nonlinear Bray-Liebhafsky reaction model" in Records of Natural Products, 118, no. 1 (2016):27-38,
https://doi.org/10.1007/s11144-016-0998-5 . .

TY  - JOUR
AU  - Stanković, Branislav
AU  - Čupić, Željko
AU  - Macesić, Stevan
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2542
AB  - The mixing of different types of bifurcations, i.e. supercritical Andronov-Hopf (SAH), double loop (DL) and saddle-loop (SL) bifurcations in the vicinity of their total annihilation, is examined on the highly nonlinear six-variable model for the Bray-Liebhafsky (BL) oscillatory reaction under continuously well-stirred tank reactor (CSTR) conditions. For this kind of the reaction system where the law of mass conservation is additional constraint that must be satisfied and where because of that, some simple bifurcations cannot be formed independently to the others, the considered transformations of the bifurcations are particularly important. That is why as the control parameters for bifurcation analysis, the specific flow rate (j(0)), as well as the inflow hydrogen peroxide concentration (h = [H2O2](in)), were used. The complex bifurcations obtained from numerical simulations are compared with some experimental results. It was shown that these complex bifurcations cannot be easily recognized in experimental investigations without knowing their evolution.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Chaos Solitons & Fractals
T1  - Complex bifurcations in the oscillatory reaction model
VL  - 87
SP  - 84
EP  - 91
DO  - 10.1016/j.chaos.2016.03.013
ER  - 

@article{
author = "Stanković, Branislav and Čupić, Željko and Macesić, Stevan and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2016",
abstract = "The mixing of different types of bifurcations, i.e. supercritical Andronov-Hopf (SAH), double loop (DL) and saddle-loop (SL) bifurcations in the vicinity of their total annihilation, is examined on the highly nonlinear six-variable model for the Bray-Liebhafsky (BL) oscillatory reaction under continuously well-stirred tank reactor (CSTR) conditions. For this kind of the reaction system where the law of mass conservation is additional constraint that must be satisfied and where because of that, some simple bifurcations cannot be formed independently to the others, the considered transformations of the bifurcations are particularly important. That is why as the control parameters for bifurcation analysis, the specific flow rate (j(0)), as well as the inflow hydrogen peroxide concentration (h = [H2O2](in)), were used. The complex bifurcations obtained from numerical simulations are compared with some experimental results. It was shown that these complex bifurcations cannot be easily recognized in experimental investigations without knowing their evolution.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Chaos Solitons & Fractals",
title = "Complex bifurcations in the oscillatory reaction model",
volume = "87",
pages = "84-91",
doi = "10.1016/j.chaos.2016.03.013"
}

Stanković, B., Čupić, Ž., Macesić, S., Pejić, N.,& Kolar-Anić, L.. (2016). Complex bifurcations in the oscillatory reaction model. in Chaos Solitons & Fractals
Pergamon-Elsevier Science Ltd, Oxford., 87, 84-91.
https://doi.org/10.1016/j.chaos.2016.03.013

Stanković B, Čupić Ž, Macesić S, Pejić N, Kolar-Anić L. Complex bifurcations in the oscillatory reaction model. in Chaos Solitons & Fractals. 2016;87:84-91.
doi:10.1016/j.chaos.2016.03.013 .

Stanković, Branislav, Čupić, Željko, Macesić, Stevan, Pejić, Nataša, Kolar-Anić, Ljiljana, "Complex bifurcations in the oscillatory reaction model" in Chaos Solitons & Fractals, 87 (2016):84-91,
https://doi.org/10.1016/j.chaos.2016.03.013 . .

TY  - JOUR
AU  - Macesic, Stevan R.
AU  - Čupić, Željko
AU  - Blagojević, Slavica
AU  - Pejić, Nataša
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2455
AB  - In stoichiometric network analysis (SNA) the instability condition is calculated by the current rates. Recently, we have shown that in the final result the current rates can be substituted by reaction rates, which is a more appropriate value for the examination of instability from experimental point of view. Here, we elaborate the problem of whether the current rates are necessary parameters in the calculation, with the aim of obtaining the region of instability. All calculations are performed on a model for Belousov-Zhabotinsky (BZ) reaction, which has not been examined by SNA.
PB  - De Gruyter Open Ltd, Warsaw
T2  - Open Chemistry
T1  - Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)
VL  - 13
IS  - 1
SP  - 591
EP  - 599
DO  - 10.1515/chem-2015-0077
ER  - 

@article{
author = "Macesic, Stevan R. and Čupić, Željko and Blagojević, Slavica and Pejić, Nataša and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2015",
abstract = "In stoichiometric network analysis (SNA) the instability condition is calculated by the current rates. Recently, we have shown that in the final result the current rates can be substituted by reaction rates, which is a more appropriate value for the examination of instability from experimental point of view. Here, we elaborate the problem of whether the current rates are necessary parameters in the calculation, with the aim of obtaining the region of instability. All calculations are performed on a model for Belousov-Zhabotinsky (BZ) reaction, which has not been examined by SNA.",
publisher = "De Gruyter Open Ltd, Warsaw",
journal = "Open Chemistry",
title = "Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)",
volume = "13",
number = "1",
pages = "591-599",
doi = "10.1515/chem-2015-0077"
}

Macesic, S. R., Čupić, Ž., Blagojević, S., Pejić, N., Anić, S.,& Kolar-Anić, L.. (2015). Current rates and reaction rates in the Stoichiometric Network Analysis (SNA). in Open Chemistry
De Gruyter Open Ltd, Warsaw., 13(1), 591-599.
https://doi.org/10.1515/chem-2015-0077

Macesic SR, Čupić Ž, Blagojević S, Pejić N, Anić S, Kolar-Anić L. Current rates and reaction rates in the Stoichiometric Network Analysis (SNA). in Open Chemistry. 2015;13(1):591-599.
doi:10.1515/chem-2015-0077 .

Macesic, Stevan R., Čupić, Željko, Blagojević, Slavica, Pejić, Nataša, Anić, Slobodan, Kolar-Anić, Ljiljana, "Current rates and reaction rates in the Stoichiometric Network Analysis (SNA)" in Open Chemistry, 13, no. 1 (2015):591-599,
https://doi.org/10.1515/chem-2015-0077 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Blagojević, Slavica
AU  - Sarap, Nataša B.
AU  - Maksimović, Jelena
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2172
AB  - Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.
PB  - Wiley-VCH Verlag GMBH, Weinheim
T2  - Helvetica Chimica Acta
T1  - Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations
VL  - 97
IS  - 1
SP  - 47
EP  - 55
DO  - 10.1002/hlca.201300109
ER  - 

@article{
author = "Pejić, Nataša and Blagojević, Slavica and Sarap, Nataša B. and Maksimović, Jelena and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2014",
abstract = "Perturbation of the BrayLiebhafsky non-oscillating subsystem (mixture of KIO3 and H2SO4), i.e., Dushman reaction (DR), by piroxicam (PX), was observed in an open reactor, i.e., in the continuously fed well-stirred tank reactor (CSTR). Monitoring the response of DR to perturbations by different concentrations of PX allows developing a simple procedure for quantitative determination of this analyte in both bulk drug and pharmaceutical preparation (injection). A tentative perturbation mechanism of PX action on the DR matrix, based on a kinetic scheme that was suggested by Agreda etal., is proposed. The PX reactivity in DR has been generally related to the reaction of PX with hypoiodous acid (HIO) present in the matrix.",
publisher = "Wiley-VCH Verlag GMBH, Weinheim",
journal = "Helvetica Chimica Acta",
title = "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations",
volume = "97",
number = "1",
pages = "47-55",
doi = "10.1002/hlca.201300109"
}

Pejić, N., Blagojević, S., Sarap, N. B., Maksimović, J., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2014). Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta
Wiley-VCH Verlag GMBH, Weinheim., 97(1), 47-55.
https://doi.org/10.1002/hlca.201300109

Pejić N, Blagojević S, Sarap NB, Maksimović J, Anić S, Čupić Ž, Kolar-Anić L. Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations. in Helvetica Chimica Acta. 2014;97(1):47-55.
doi:10.1002/hlca.201300109 .

Pejić, Nataša, Blagojević, Slavica, Sarap, Nataša B., Maksimović, Jelena, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Perturbations of the Dushman Reaction with Piroxicam: Experimental and Model Calculations" in Helvetica Chimica Acta, 97, no. 1 (2014):47-55,
https://doi.org/10.1002/hlca.201300109 . .

TY  - JOUR
AU  - Stanković, Branislav
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2031
AB  - The time series obtained by numerical simulations of the model of the Bray-Liebhafsky oscillatory reaction is analyzed under the continuously fed well stirred tank reactor (CSTR) conditions, with the aim to find bifurcation points in which system of Bray- Liebhafsky oscillatory reaction transforms from stable to unstable state and vice versa. Types of bifurcation points, supercritical and subcritical Andronov-Hopf bifurcation and saddle-loop bifurcation are determined from characteristic scaling laws.
PB  - L and H Scientific Publishing, LLC
T2  - Journal of Applied Nonlinear Dynamics
T1  - Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations
VL  - 2
IS  - 3
SP  - 285
EP  - 301
DO  - 10.5890/JAND.2013.08.004
ER  - 

@article{
author = "Stanković, Branislav and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2013",
abstract = "The time series obtained by numerical simulations of the model of the Bray-Liebhafsky oscillatory reaction is analyzed under the continuously fed well stirred tank reactor (CSTR) conditions, with the aim to find bifurcation points in which system of Bray- Liebhafsky oscillatory reaction transforms from stable to unstable state and vice versa. Types of bifurcation points, supercritical and subcritical Andronov-Hopf bifurcation and saddle-loop bifurcation are determined from characteristic scaling laws.",
publisher = "L and H Scientific Publishing, LLC",
journal = "Journal of Applied Nonlinear Dynamics",
title = "Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations",
volume = "2",
number = "3",
pages = "285-301",
doi = "10.5890/JAND.2013.08.004"
}

Stanković, B., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2013). Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations. in Journal of Applied Nonlinear Dynamics
L and H Scientific Publishing, LLC., 2(3), 285-301.
https://doi.org/10.5890/JAND.2013.08.004

Stanković B, Čupić Ž, Pejić N, Kolar-Anić L. Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations. in Journal of Applied Nonlinear Dynamics. 2013;2(3):285-301.
doi:10.5890/JAND.2013.08.004 .

Stanković, Branislav, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Numerical study on Bray-Liebhafsky oscillatory reaction: Bifurcations" in Journal of Applied Nonlinear Dynamics, 2, no. 3 (2013):285-301,
https://doi.org/10.5890/JAND.2013.08.004 . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Maksimović, Jelena
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1655
AB  - Simple and reliable novel methods for the determination of uric acid (UA) are proposed and validated. For quantitative determination of UA, two matrices were used: the Bray-Liebhafsky (BL) oscillatory reaction in a stable non-equilibrium stationary state close to the bifurcation point (method A) as well as, the BL non-oscillating subsystem (mixture KIO3 and H2SO4), i.e., Dushman reaction (DR) in a steady state (method B). The proposed methods are optimized in a continuously fed well stirred tank reactor (CSTR) and applied with excellent results in the determination of UA in human urine samples. The linear relationship between maximal potential shift Delta E-m, and both the logarithm of the UA concentration (procedure A) and UA concentration (procedure B) is obtained in the concentration range 2.98 x 10(-5)-2.68 x 10(-4) mol L-1 and 2.98 x 10(-5)-3.58 x 10(-4) mol L-1, respectively. The methods have an excellent sample throughput of 30 samples h(-1) (method A) and 7 samples h(-1) (method B) with the sensitivity determined to be 1.1 x 10(-5) mol L-1 (method A) and 8.9 x 10(-6) mol L-1 (method B) as well as the precision RSD  lt = 3.4% for both methods. Some aspects of the possible mechanism of UA action on the BL oscillating and Duschman non-oscillating reaction systems are discussed in detail.
PB  - Soc Brasileira Quimica, Sao Paulo
T2  - Journal of the Brazilian Chemical Society
T1  - Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique
VL  - 23
IS  - 8
SP  - 1450
EP  - 1459
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1655
ER  - 

@article{
author = "Pejić, Nataša and Maksimović, Jelena and Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2012",
abstract = "Simple and reliable novel methods for the determination of uric acid (UA) are proposed and validated. For quantitative determination of UA, two matrices were used: the Bray-Liebhafsky (BL) oscillatory reaction in a stable non-equilibrium stationary state close to the bifurcation point (method A) as well as, the BL non-oscillating subsystem (mixture KIO3 and H2SO4), i.e., Dushman reaction (DR) in a steady state (method B). The proposed methods are optimized in a continuously fed well stirred tank reactor (CSTR) and applied with excellent results in the determination of UA in human urine samples. The linear relationship between maximal potential shift Delta E-m, and both the logarithm of the UA concentration (procedure A) and UA concentration (procedure B) is obtained in the concentration range 2.98 x 10(-5)-2.68 x 10(-4) mol L-1 and 2.98 x 10(-5)-3.58 x 10(-4) mol L-1, respectively. The methods have an excellent sample throughput of 30 samples h(-1) (method A) and 7 samples h(-1) (method B) with the sensitivity determined to be 1.1 x 10(-5) mol L-1 (method A) and 8.9 x 10(-6) mol L-1 (method B) as well as the precision RSD  lt = 3.4% for both methods. Some aspects of the possible mechanism of UA action on the BL oscillating and Duschman non-oscillating reaction systems are discussed in detail.",
publisher = "Soc Brasileira Quimica, Sao Paulo",
journal = "Journal of the Brazilian Chemical Society",
title = "Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique",
volume = "23",
number = "8",
pages = "1450-1459",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1655"
}

Pejić, N., Maksimović, J., Blagojević, S., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2012). Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique. in Journal of the Brazilian Chemical Society
Soc Brasileira Quimica, Sao Paulo., 23(8), 1450-1459.
https://hdl.handle.net/21.15107/rcub_farfar_1655

Pejić N, Maksimović J, Blagojević S, Anić S, Čupić Ž, Kolar-Anić L. Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique. in Journal of the Brazilian Chemical Society. 2012;23(8):1450-1459.
https://hdl.handle.net/21.15107/rcub_farfar_1655 .

Pejić, Nataša, Maksimović, Jelena, Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Kinetic Analytical Method for Determination of Uric Acid in Human Urine using Analyte Pulse Perturbation Technique" in Journal of the Brazilian Chemical Society, 23, no. 8 (2012):1450-1459,
https://hdl.handle.net/21.15107/rcub_farfar_1655 .

TY  - JOUR
AU  - Maksimović, Jelena
AU  - Čupić, Željko
AU  - Lončarević, D.
AU  - Pejić, Nataša
AU  - Vasiljević-Radović, D.
AU  - Anić, Slobodan
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1575
AB  - The Bray-Liebhafsky (BL) oscillatory reaction generated in the batch reactor at 62- 68 oC was perturbed by cobalt(II)-nitrate, supported on the macroreticular copolymer of poly-4-vinylpyridine with divinylbenzene (Co-PVPDVB). The kinetic data was analyzed of the complex pathways of the hydrogen peroxide decomposition in the examined BL reaction. The obtained results confirm that the kinetics of the BL reaction in the presence Co-PVPDVB comes partially from the Co-catalyst and partially from the macroreticular copolymer support.
AB  - Oscilatorna reakcija Bray-Liebhafsky (BL) realizovana u zatvorenom reaktoru na temperaturi 62-68 oC je perturbovana sa kobalt(II)nitratom ugrađenim na makroretikularnom kopolimeru poli-4-vinilpiridina sa divinilbenzenom (Co- PVPDVB). Analizirani su kinetički podaci kompleksnih reakcionih puteva razlaganja vodonikperoksida u ispitivanoj BL reakciji. Dobijeni rezultati potvrđuju da je u prisustvu Co-PVPDVB kinetika BL reakcije delimično određena Co-katalizatorom, a delimično makromolekularnim kopolimernim nosačem katalizatora.
PB  - Međunarodni Institut za nauku o sinterovanju, Beograd
T2  - Science of Sintering
T1  - Kinetics of the Bray-Liebhafsky oscillatory reaction perturbed by polymer supported cobalt catalyst
VL  - 43
IS  - 1
SP  - 55
EP  - 62
DO  - 10.2298/SOS1101055M
ER  - 

@article{
author = "Maksimović, Jelena and Čupić, Željko and Lončarević, D. and Pejić, Nataša and Vasiljević-Radović, D. and Anić, Slobodan",
year = "2011",
abstract = "The Bray-Liebhafsky (BL) oscillatory reaction generated in the batch reactor at 62- 68 oC was perturbed by cobalt(II)-nitrate, supported on the macroreticular copolymer of poly-4-vinylpyridine with divinylbenzene (Co-PVPDVB). The kinetic data was analyzed of the complex pathways of the hydrogen peroxide decomposition in the examined BL reaction. The obtained results confirm that the kinetics of the BL reaction in the presence Co-PVPDVB comes partially from the Co-catalyst and partially from the macroreticular copolymer support., Oscilatorna reakcija Bray-Liebhafsky (BL) realizovana u zatvorenom reaktoru na temperaturi 62-68 oC je perturbovana sa kobalt(II)nitratom ugrađenim na makroretikularnom kopolimeru poli-4-vinilpiridina sa divinilbenzenom (Co- PVPDVB). Analizirani su kinetički podaci kompleksnih reakcionih puteva razlaganja vodonikperoksida u ispitivanoj BL reakciji. Dobijeni rezultati potvrđuju da je u prisustvu Co-PVPDVB kinetika BL reakcije delimično određena Co-katalizatorom, a delimično makromolekularnim kopolimernim nosačem katalizatora.",
publisher = "Međunarodni Institut za nauku o sinterovanju, Beograd",
journal = "Science of Sintering",
title = "Kinetics of the Bray-Liebhafsky oscillatory reaction perturbed by polymer supported cobalt catalyst",
volume = "43",
number = "1",
pages = "55-62",
doi = "10.2298/SOS1101055M"
}

Maksimović, J., Čupić, Ž., Lončarević, D., Pejić, N., Vasiljević-Radović, D.,& Anić, S.. (2011). Kinetics of the Bray-Liebhafsky oscillatory reaction perturbed by polymer supported cobalt catalyst. in Science of Sintering
Međunarodni Institut za nauku o sinterovanju, Beograd., 43(1), 55-62.
https://doi.org/10.2298/SOS1101055M

Maksimović J, Čupić Ž, Lončarević D, Pejić N, Vasiljević-Radović D, Anić S. Kinetics of the Bray-Liebhafsky oscillatory reaction perturbed by polymer supported cobalt catalyst. in Science of Sintering. 2011;43(1):55-62.
doi:10.2298/SOS1101055M .

Maksimović, Jelena, Čupić, Željko, Lončarević, D., Pejić, Nataša, Vasiljević-Radović, D., Anić, Slobodan, "Kinetics of the Bray-Liebhafsky oscillatory reaction perturbed by polymer supported cobalt catalyst" in Science of Sintering, 43, no. 1 (2011):55-62,
https://doi.org/10.2298/SOS1101055M . .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Vujković, Milica
AU  - Maksimović, Jelena
AU  - Ivanović, A.
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Kolar-Anić, Ljiljana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1516
AB  - The non-periodic, periodic and chaotic regimes in the Bray-Liebhafsky (BL) oscillatory reaction observed in a continuously fed well stirred tank reactor (CSTR) under isothermal conditions at various inflow concentrations of the sulfuric acid were experimentally studied. In each series (at any fixed temperature), termination of oscillatory behavior via saddle loop infinite period bifurcation (SNIPER) as well as some kind of the Andronov-Hopf bifurcation is presented. In addition, it was found that an increase of temperature, in different series of experiments resulted in the shift of bifurcation point towards higher values of sulfuric acid concentration.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature
VL  - 85
IS  - 13
SP  - 2310
EP  - 2316
DO  - 10.1134/S0036024411130231
ER  - 

@article{
author = "Pejić, Nataša and Vujković, Milica and Maksimović, Jelena and Ivanović, A. and Anić, Slobodan and Čupić, Željko and Kolar-Anić, Ljiljana",
year = "2011",
abstract = "The non-periodic, periodic and chaotic regimes in the Bray-Liebhafsky (BL) oscillatory reaction observed in a continuously fed well stirred tank reactor (CSTR) under isothermal conditions at various inflow concentrations of the sulfuric acid were experimentally studied. In each series (at any fixed temperature), termination of oscillatory behavior via saddle loop infinite period bifurcation (SNIPER) as well as some kind of the Andronov-Hopf bifurcation is presented. In addition, it was found that an increase of temperature, in different series of experiments resulted in the shift of bifurcation point towards higher values of sulfuric acid concentration.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature",
volume = "85",
number = "13",
pages = "2310-2316",
doi = "10.1134/S0036024411130231"
}

Pejić, N., Vujković, M., Maksimović, J., Ivanović, A., Anić, S., Čupić, Ž.,& Kolar-Anić, L.. (2011). Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 85(13), 2310-2316.
https://doi.org/10.1134/S0036024411130231

Pejić N, Vujković M, Maksimović J, Ivanović A, Anić S, Čupić Ž, Kolar-Anić L. Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature. in SAR and QSAR in Environmental Research. 2011;85(13):2310-2316.
doi:10.1134/S0036024411130231 .

Pejić, Nataša, Vujković, Milica, Maksimović, Jelena, Ivanović, A., Anić, Slobodan, Čupić, Željko, Kolar-Anić, Ljiljana, "Dynamic behavior of the bray-liebhafsky oscillatory reaction controlled by sulfuric acid and temperature" in SAR and QSAR in Environmental Research, 85, no. 13 (2011):2310-2316,
https://doi.org/10.1134/S0036024411130231 . .

TY  - JOUR
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1515
AB  - In the already proposed model of the Belousov-Zhabotinsky reaction with the Br(2)O species as intermediate one, the reactions with malonyl (MA(center dot)), bromomalonyl (BrMA(center dot)) and tartronyl (TA(center dot)) radicals were introduced with aim to explore their role in overall dynamics. The related numerical simulations of the experimentally obtained dynamic states under batch conditions were successfully performed.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Influence of most important radicals on the numerically simulated belousov-zhabotinsky oscillatory reaction under batch conditions
VL  - 85
IS  - 13
SP  - 2274
EP  - 2278
DO  - 10.1134/S003602441113005X
ER  - 

@article{
author = "Blagojević, Slavica and Anić, Slobodan and Čupić, Željko",
year = "2011",
abstract = "In the already proposed model of the Belousov-Zhabotinsky reaction with the Br(2)O species as intermediate one, the reactions with malonyl (MA(center dot)), bromomalonyl (BrMA(center dot)) and tartronyl (TA(center dot)) radicals were introduced with aim to explore their role in overall dynamics. The related numerical simulations of the experimentally obtained dynamic states under batch conditions were successfully performed.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Influence of most important radicals on the numerically simulated belousov-zhabotinsky oscillatory reaction under batch conditions",
volume = "85",
number = "13",
pages = "2274-2278",
doi = "10.1134/S003602441113005X"
}

Blagojević, S., Anić, S.,& Čupić, Ž.. (2011). Influence of most important radicals on the numerically simulated belousov-zhabotinsky oscillatory reaction under batch conditions. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 85(13), 2274-2278.
https://doi.org/10.1134/S003602441113005X

Blagojević S, Anić S, Čupić Ž. Influence of most important radicals on the numerically simulated belousov-zhabotinsky oscillatory reaction under batch conditions. in SAR and QSAR in Environmental Research. 2011;85(13):2274-2278.
doi:10.1134/S003602441113005X .

Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, "Influence of most important radicals on the numerically simulated belousov-zhabotinsky oscillatory reaction under batch conditions" in SAR and QSAR in Environmental Research, 85, no. 13 (2011):2274-2278,
https://doi.org/10.1134/S003602441113005X . .

TY  - JOUR
AU  - Anić, Slobodan
AU  - Maksimović, Jelena
AU  - Loncarević, D.
AU  - Pejić, Nataša
AU  - Čupić, Željko
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1258
AB  - The infuence of poly-4-vinylpyridine-co-divinylbenzene-Co2+ catalyst on the Bray-Liebhafsky (BL) oscillator used as the matrix for establishing catalyst's activity was analyzed. The addition of the catalyst do not change the dynamics of the reaction in the BL matrix, but the periods of the oscillatory evolution as well as the preoscillatory period (tau(1)) and the duration from the beginning of the reaction to the end of the oscillatory state (tau(end)). All experimental results are simulated satisfactory.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Activity of polymer supported cobalt catalyst in the Bray-Liebhafsky oscillator
VL  - 83
IS  - 9
SP  - 1468
EP  - 1472
DO  - 10.1134/S003602440909009X
ER  - 

@article{
author = "Anić, Slobodan and Maksimović, Jelena and Loncarević, D. and Pejić, Nataša and Čupić, Željko",
year = "2009",
abstract = "The infuence of poly-4-vinylpyridine-co-divinylbenzene-Co2+ catalyst on the Bray-Liebhafsky (BL) oscillator used as the matrix for establishing catalyst's activity was analyzed. The addition of the catalyst do not change the dynamics of the reaction in the BL matrix, but the periods of the oscillatory evolution as well as the preoscillatory period (tau(1)) and the duration from the beginning of the reaction to the end of the oscillatory state (tau(end)). All experimental results are simulated satisfactory.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Activity of polymer supported cobalt catalyst in the Bray-Liebhafsky oscillator",
volume = "83",
number = "9",
pages = "1468-1472",
doi = "10.1134/S003602440909009X"
}

Anić, S., Maksimović, J., Loncarević, D., Pejić, N.,& Čupić, Ž.. (2009). Activity of polymer supported cobalt catalyst in the Bray-Liebhafsky oscillator. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 83(9), 1468-1472.
https://doi.org/10.1134/S003602440909009X

Anić S, Maksimović J, Loncarević D, Pejić N, Čupić Ž. Activity of polymer supported cobalt catalyst in the Bray-Liebhafsky oscillator. in SAR and QSAR in Environmental Research. 2009;83(9):1468-1472.
doi:10.1134/S003602440909009X .

Anić, Slobodan, Maksimović, Jelena, Loncarević, D., Pejić, Nataša, Čupić, Željko, "Activity of polymer supported cobalt catalyst in the Bray-Liebhafsky oscillator" in SAR and QSAR in Environmental Research, 83, no. 9 (2009):1468-1472,
https://doi.org/10.1134/S003602440909009X . .

TY  - JOUR
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1254
AB  - The kinetic investigations of the malonic acid decomposition (8.00 x 10(-3) mol dm(-3) a parts per thousand currency sign [CH(2)(COOH)(2)](0) a parts per thousand currency sign 4.30 x 10(-2) mol dm(-3)) in the Belousov-Zhabotinsky (BZ) system in the presence of bromate, bromide, sulfuric acid and cerium sulfate, were performed in the isothermal closed well stirred reactor at different temperatures (25.0A degrees C a parts per thousand currency sign T a parts per thousand currency sign 45.0A degrees C). The formal kinetics of the overall BZ reaction, and particularly kinetics in characteristic periods of BZ reaction, based on the analyses of the bromide oscillograms, was accomplished. The evolution as well as the rate constants and the apparent activation energies of the reactions, which exist in the preoscillatory and oscillatory periods, are also successfully calculated by numerical simulations. Simulations are based on the model including the Br(2)O species.
PB  - Maik Nauka/Interperiodica/Springer, New York
T2  - SAR and QSAR in Environmental Research
T1  - Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction
VL  - 83
IS  - 9
SP  - 1496
EP  - 1501
DO  - 10.1134/S0036024409090143
ER  - 

@article{
author = "Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2009",
abstract = "The kinetic investigations of the malonic acid decomposition (8.00 x 10(-3) mol dm(-3) a parts per thousand currency sign [CH(2)(COOH)(2)](0) a parts per thousand currency sign 4.30 x 10(-2) mol dm(-3)) in the Belousov-Zhabotinsky (BZ) system in the presence of bromate, bromide, sulfuric acid and cerium sulfate, were performed in the isothermal closed well stirred reactor at different temperatures (25.0A degrees C a parts per thousand currency sign T a parts per thousand currency sign 45.0A degrees C). The formal kinetics of the overall BZ reaction, and particularly kinetics in characteristic periods of BZ reaction, based on the analyses of the bromide oscillograms, was accomplished. The evolution as well as the rate constants and the apparent activation energies of the reactions, which exist in the preoscillatory and oscillatory periods, are also successfully calculated by numerical simulations. Simulations are based on the model including the Br(2)O species.",
publisher = "Maik Nauka/Interperiodica/Springer, New York",
journal = "SAR and QSAR in Environmental Research",
title = "Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction",
volume = "83",
number = "9",
pages = "1496-1501",
doi = "10.1134/S0036024409090143"
}

Blagojević, S., Anić, S., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2009). Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction. in SAR and QSAR in Environmental Research
Maik Nauka/Interperiodica/Springer, New York., 83(9), 1496-1501.
https://doi.org/10.1134/S0036024409090143

Blagojević S, Anić S, Čupić Ž, Pejić N, Kolar-Anić L. Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction. in SAR and QSAR in Environmental Research. 2009;83(9):1496-1501.
doi:10.1134/S0036024409090143 .

Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Temperature influence on the malonic acid decomposition in the Belousov-Zhabotinsky reaction" in SAR and QSAR in Environmental Research, 83, no. 9 (2009):1496-1501,
https://doi.org/10.1134/S0036024409090143 . .

TY  - JOUR
AU  - Blagojević, Slavica
AU  - Anić, Slobodan
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Kolar-Anić, Ljiljana
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1027
AB  - The influence of the initial malonic acid concentration [MA](0) (8.00 x 10(-3)  lt = [MA](0)  lt = 4.30 x 10(-2) mol dm(-3)) in the presence of bromate (6.20 x 10(-2) mol dm(-3)), bromide (1.50 x 10(-5) mol dm(-3)), sulfuric acid (1.00 mol dm(-3)) and cerium sulfate (2.50 x 10(-3) mol dm(-3)) on the dynamics and the kinetics of the Belousov-Zhabotinsky (BZ) reactions was examined under batch conditions at 30.0 degrees C. The kinetics of the BZ reaction was analyzed by the earlier proposed method convenient for the examinations of the oscillatory reactions. In the defined region of parameters where oscillograms with only large-amplitude relaxation oscillations appeared, the pseudo-first order of the overall malonic acid decomposition with a corresponding rate constant of 2.14 x 10(-2) min(-1) was established. The numerical results on the dynamics and kinetics of the BZ reaction, carried out by the known skeleton model including the Br2O species, were in good agreement with the experimental ones. The already found saddle node infinite period (SNIPER) bifurcation point in transition from a stable quasi-steady state to periodic orbits and vice versa is confirmed by both experimental and numerical investigations of the system under consideration. Namely, the large-amplitude relaxation oscillations with increasing periods between oscillations in approaching the bifurcation points at the beginning and the end of the oscillatory domain, together with excitability of the stable quasi-steady states in their vicinity are obtained.
PB  - Royal Soc Chemistry, Cambridge
T2  - Physical Chemistry Chemical Physics
T1  - Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions
VL  - 10
IS  - 44
SP  - 6658
EP  - 6664
DO  - 10.1039/b804919j
ER  - 

@article{
author = "Blagojević, Slavica and Anić, Slobodan and Čupić, Željko and Pejić, Nataša and Kolar-Anić, Ljiljana",
year = "2008",
abstract = "The influence of the initial malonic acid concentration [MA](0) (8.00 x 10(-3)  lt = [MA](0)  lt = 4.30 x 10(-2) mol dm(-3)) in the presence of bromate (6.20 x 10(-2) mol dm(-3)), bromide (1.50 x 10(-5) mol dm(-3)), sulfuric acid (1.00 mol dm(-3)) and cerium sulfate (2.50 x 10(-3) mol dm(-3)) on the dynamics and the kinetics of the Belousov-Zhabotinsky (BZ) reactions was examined under batch conditions at 30.0 degrees C. The kinetics of the BZ reaction was analyzed by the earlier proposed method convenient for the examinations of the oscillatory reactions. In the defined region of parameters where oscillograms with only large-amplitude relaxation oscillations appeared, the pseudo-first order of the overall malonic acid decomposition with a corresponding rate constant of 2.14 x 10(-2) min(-1) was established. The numerical results on the dynamics and kinetics of the BZ reaction, carried out by the known skeleton model including the Br2O species, were in good agreement with the experimental ones. The already found saddle node infinite period (SNIPER) bifurcation point in transition from a stable quasi-steady state to periodic orbits and vice versa is confirmed by both experimental and numerical investigations of the system under consideration. Namely, the large-amplitude relaxation oscillations with increasing periods between oscillations in approaching the bifurcation points at the beginning and the end of the oscillatory domain, together with excitability of the stable quasi-steady states in their vicinity are obtained.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Physical Chemistry Chemical Physics",
title = "Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions",
volume = "10",
number = "44",
pages = "6658-6664",
doi = "10.1039/b804919j"
}

Blagojević, S., Anić, S., Čupić, Ž., Pejić, N.,& Kolar-Anić, L.. (2008). Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions. in Physical Chemistry Chemical Physics
Royal Soc Chemistry, Cambridge., 10(44), 6658-6664.
https://doi.org/10.1039/b804919j

Blagojević S, Anić S, Čupić Ž, Pejić N, Kolar-Anić L. Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions. in Physical Chemistry Chemical Physics. 2008;10(44):6658-6664.
doi:10.1039/b804919j .

Blagojević, Slavica, Anić, Slobodan, Čupić, Željko, Pejić, Nataša, Kolar-Anić, Ljiljana, "Malonic acid concentration as a control parameter in the kinetic analysis of the Belousov-Zhabotinsky reaction under batch conditions" in Physical Chemistry Chemical Physics, 10, no. 44 (2008):6658-6664,
https://doi.org/10.1039/b804919j . .

TY  - JOUR
AU  - Milošević, M
AU  - Pejić, Nataša
AU  - Čupić, Željko
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/575
AB  - Macroporous cross-linked copolymer of 4-vinylpyridine and 25% (4: 1) divinylbenzene is analyzed under open conditions, that is in a continuous well-stirred tank reactor (CSTR). With this aim the appropriate bifurcation diagram is found and the behavior of the system with and without polymer in the vicinity of the bifurcation point is used for the polymer examinations. Two different granulations of polymer are considered. Moreover, some physicochemical characteristics of the polymer, such as specific surface area, skeletal and particle density, are determined.
PB  - Trans Tech Publications Ltd, Durnten-Zurich
T2  - Current Research in Advanced Materials and Processes
T1  - Examinations of cross-linked polyvinylpyridine in open reactor
VL  - 494
SP  - 369
EP  - 374
DO  - 10.4028/www.scientific.net/MSF.494.369
ER  - 

@article{
author = "Milošević, M and Pejić, Nataša and Čupić, Željko and Anić, Slobodan and Kolar-Anić, Ljiljana",
year = "2005",
abstract = "Macroporous cross-linked copolymer of 4-vinylpyridine and 25% (4: 1) divinylbenzene is analyzed under open conditions, that is in a continuous well-stirred tank reactor (CSTR). With this aim the appropriate bifurcation diagram is found and the behavior of the system with and without polymer in the vicinity of the bifurcation point is used for the polymer examinations. Two different granulations of polymer are considered. Moreover, some physicochemical characteristics of the polymer, such as specific surface area, skeletal and particle density, are determined.",
publisher = "Trans Tech Publications Ltd, Durnten-Zurich",
journal = "Current Research in Advanced Materials and Processes",
title = "Examinations of cross-linked polyvinylpyridine in open reactor",
volume = "494",
pages = "369-374",
doi = "10.4028/www.scientific.net/MSF.494.369"
}

Milošević, M., Pejić, N., Čupić, Ž., Anić, S.,& Kolar-Anić, L.. (2005). Examinations of cross-linked polyvinylpyridine in open reactor. in Current Research in Advanced Materials and Processes
Trans Tech Publications Ltd, Durnten-Zurich., 494, 369-374.
https://doi.org/10.4028/www.scientific.net/MSF.494.369

Milošević M, Pejić N, Čupić Ž, Anić S, Kolar-Anić L. Examinations of cross-linked polyvinylpyridine in open reactor. in Current Research in Advanced Materials and Processes. 2005;494:369-374.
doi:10.4028/www.scientific.net/MSF.494.369 .

Milošević, M, Pejić, Nataša, Čupić, Željko, Anić, Slobodan, Kolar-Anić, Ljiljana, "Examinations of cross-linked polyvinylpyridine in open reactor" in Current Research in Advanced Materials and Processes, 494 (2005):369-374,
https://doi.org/10.4028/www.scientific.net/MSF.494.369 . .

TY  - JOUR
AU  - Anić, Slobodan
AU  - Kolar-Anić, Ljiljana
AU  - Čupić, Željko
AU  - Pejić, Nataša
AU  - Vukojević, Vladana
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/307
AB  - The main kinetic characteristics of a catalyst could be obtained by examination of its behavior in some known reaction system, so-called model reaction system. The model reaction system is usually chosen to be as simple as possible. Therefore, for this purpose, the first or second order reaction with relatively simple mechanism and with only one reaction pathway is often selected. However, for the model reaction system one oscillatory chemical reaction, having the complex mechanism with the alternating reaction pathways, could be chosen. It can be expressed over the state far from equilibrium and the variety of kinetic characteristics, resulting from the properties of examined catalyst, can be found. The special attention is paid on Bray-Liebhafsky oscillatory chemical reaction, as well as on the comparative analysis of the iron based catalysts, whereby iron could be used either as peroxydazirene or supported on acidic polyvinylpyridine. .
AB  - Glavne kinetičke karakteristike katalizatora dobijaju se ispitivanjem njegovog ponašanja u nekom poznatom reakcionom sistemu, takozvanom modelnom reakcionom sistemu. Za modelni reakcioni sistem obično se bira što je moguće jednostavniji. Zbog toga se, u tu svrhu, najčešće koristi neka reakcija prvog ili drugog reda sa definisanim i jednostavnim mehanizmom i jasnom stehiometrijom ukupne reakcije, kao i samo jednim reakcionim putem. Međutim, za modelnu reakciju može se izabrati i neka složena hemijska reakcija, na primer, neka od oscilatornih hemijskih reakcija sa nizom alternativnih reakcionih puteva, a koji se ispoljavaju u nekim od njenih stanja daleko od ravnoteže. Kao takva, veoma je osetljiva na uvođenje katalizatora čija svojstva želimo ispitati. Ovom prilikom pažnja je posvećena modelnoj Bray-Liebhafsky (BL) oscilatornoj reakciji i uporednoj analizi katalizatora na bazi gvožda bilo da je u pitanju gvožđe u peroksidazi rena ili ono naneto na kiseli polivinilpiridin. .
PB  - Društvo inženjera plastičara i gumara, Beograd
T2  - Svet polimera
T1  - Oscillatory chemical reaction as model system for the catalysts characterization
T1  - Oscilatorna hemijska reakcija kao modelni sistem za karakterizaciju katalizatora
VL  - 4
IS  - 2
SP  - 55
EP  - 66
UR  - https://hdl.handle.net/21.15107/rcub_cer_41
ER  - 

@article{
author = "Anić, Slobodan and Kolar-Anić, Ljiljana and Čupić, Željko and Pejić, Nataša and Vukojević, Vladana",
year = "2001",
abstract = "The main kinetic characteristics of a catalyst could be obtained by examination of its behavior in some known reaction system, so-called model reaction system. The model reaction system is usually chosen to be as simple as possible. Therefore, for this purpose, the first or second order reaction with relatively simple mechanism and with only one reaction pathway is often selected. However, for the model reaction system one oscillatory chemical reaction, having the complex mechanism with the alternating reaction pathways, could be chosen. It can be expressed over the state far from equilibrium and the variety of kinetic characteristics, resulting from the properties of examined catalyst, can be found. The special attention is paid on Bray-Liebhafsky oscillatory chemical reaction, as well as on the comparative analysis of the iron based catalysts, whereby iron could be used either as peroxydazirene or supported on acidic polyvinylpyridine. ., Glavne kinetičke karakteristike katalizatora dobijaju se ispitivanjem njegovog ponašanja u nekom poznatom reakcionom sistemu, takozvanom modelnom reakcionom sistemu. Za modelni reakcioni sistem obično se bira što je moguće jednostavniji. Zbog toga se, u tu svrhu, najčešće koristi neka reakcija prvog ili drugog reda sa definisanim i jednostavnim mehanizmom i jasnom stehiometrijom ukupne reakcije, kao i samo jednim reakcionim putem. Međutim, za modelnu reakciju može se izabrati i neka složena hemijska reakcija, na primer, neka od oscilatornih hemijskih reakcija sa nizom alternativnih reakcionih puteva, a koji se ispoljavaju u nekim od njenih stanja daleko od ravnoteže. Kao takva, veoma je osetljiva na uvođenje katalizatora čija svojstva želimo ispitati. Ovom prilikom pažnja je posvećena modelnoj Bray-Liebhafsky (BL) oscilatornoj reakciji i uporednoj analizi katalizatora na bazi gvožda bilo da je u pitanju gvožđe u peroksidazi rena ili ono naneto na kiseli polivinilpiridin. .",
publisher = "Društvo inženjera plastičara i gumara, Beograd",
journal = "Svet polimera",
title = "Oscillatory chemical reaction as model system for the catalysts characterization, Oscilatorna hemijska reakcija kao modelni sistem za karakterizaciju katalizatora",
volume = "4",
number = "2",
pages = "55-66",
url = "https://hdl.handle.net/21.15107/rcub_cer_41"
}

Anić, S., Kolar-Anić, L., Čupić, Ž., Pejić, N.,& Vukojević, V.. (2001). Oscillatory chemical reaction as model system for the catalysts characterization. in Svet polimera
Društvo inženjera plastičara i gumara, Beograd., 4(2), 55-66.
https://hdl.handle.net/21.15107/rcub_cer_41

Anić S, Kolar-Anić L, Čupić Ž, Pejić N, Vukojević V. Oscillatory chemical reaction as model system for the catalysts characterization. in Svet polimera. 2001;4(2):55-66.
https://hdl.handle.net/21.15107/rcub_cer_41 .

Anić, Slobodan, Kolar-Anić, Ljiljana, Čupić, Željko, Pejić, Nataša, Vukojević, Vladana, "Oscillatory chemical reaction as model system for the catalysts characterization" in Svet polimera, 4, no. 2 (2001):55-66,
https://hdl.handle.net/21.15107/rcub_cer_41 .

TY  - JOUR
AU  - Pejić, Nataša
AU  - Čupić, Željko
AU  - Anić, Slobodan
AU  - Vukojević, Vladana
AU  - Kolar-Anić, Ljiljana
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/301
AB  - The Bray-Liebhafsky (BL) oscillatory reaction, as a reaction where hydrogen peroxide decomposes into the water and oxygen in the presence of iodate and hydrogen ions through a complex mechanism involving a number of intermediates, such as I-, I2, HIO and HIO2, was used as the matrix for analysis of kinetic properties of the catalysts for hydrogen peroxide decomposition. The examined catalysts were enzyme peroxidase (isolated from the horseradish root) and polymeric catalyst (acid form of poly-4-vynil-pyridine functionalized by fericsulfate). The change of kinetic state of the system caused by the presence of added catalyst is reflected in the form of oscillograms, in the time elapsed from the beginning of the reaction to the first oscillation, in the time elapsed from the beginning of the reaction to the end of oscillatory evolution, the number of oscillations, the average period between oscillations and its frequency. Since all these kinetic properties depend on the added amounts of both mentioned catalysts in a complex but analogous manner, a similar reaction mechanism could be expected in both cases.
AB  - Braj-Liebhafski (BL) oscilatorna reakcija, kao reakcija u kojoj se vodonik-peroksid, u prisustvu jodata i vodoničnih jona, razlaže na vodu i kiseonik, po kompleksnom mehanizmu koji uključuje nastanak brojnih intermedijera kao što su I-, I2, HIO i HIO2 je korišćena kao matrica za analizu kinetičkih osobina katalizatora za razlaganje vodonik-peroksida. Ispitivani katalizatori su peroksidaza izolovana iz korena rena i sintetički polimer (kiseli oblik poli-4-vinil-piridina funkcionalizovanog sa ferisulfatom). Promene kinetičkog stanja sistema izazvane prisustvom dodatih količina katalizatora se reflektuju na formu oscilograma, na vreme proteklo od početka reakcije do pojave prve oscilacije, na vreme proteklo od početka reakcije do kraja oscilatorne evolucije, broj oscilacija, srednjeg perioda oscilovanja i njihovu frekvenciju. Kako sva ova kinetička svojstva zavise od dodatih količina katalizatora na kompleksan ali analogan način, sličan reakcioni mehanizam se može očekivati u oba slučaja.
PB  - Međunarodni Institut za nauku o sinterovanju, Beograd
T2  - Science of Sintering
T1  - The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide
VL  - 33
IS  - 2
SP  - 107
EP  - 115
UR  - https://hdl.handle.net/21.15107/rcub_farfar_301
ER  - 

@article{
author = "Pejić, Nataša and Čupić, Željko and Anić, Slobodan and Vukojević, Vladana and Kolar-Anić, Ljiljana",
year = "2001",
abstract = "The Bray-Liebhafsky (BL) oscillatory reaction, as a reaction where hydrogen peroxide decomposes into the water and oxygen in the presence of iodate and hydrogen ions through a complex mechanism involving a number of intermediates, such as I-, I2, HIO and HIO2, was used as the matrix for analysis of kinetic properties of the catalysts for hydrogen peroxide decomposition. The examined catalysts were enzyme peroxidase (isolated from the horseradish root) and polymeric catalyst (acid form of poly-4-vynil-pyridine functionalized by fericsulfate). The change of kinetic state of the system caused by the presence of added catalyst is reflected in the form of oscillograms, in the time elapsed from the beginning of the reaction to the first oscillation, in the time elapsed from the beginning of the reaction to the end of oscillatory evolution, the number of oscillations, the average period between oscillations and its frequency. Since all these kinetic properties depend on the added amounts of both mentioned catalysts in a complex but analogous manner, a similar reaction mechanism could be expected in both cases., Braj-Liebhafski (BL) oscilatorna reakcija, kao reakcija u kojoj se vodonik-peroksid, u prisustvu jodata i vodoničnih jona, razlaže na vodu i kiseonik, po kompleksnom mehanizmu koji uključuje nastanak brojnih intermedijera kao što su I-, I2, HIO i HIO2 je korišćena kao matrica za analizu kinetičkih osobina katalizatora za razlaganje vodonik-peroksida. Ispitivani katalizatori su peroksidaza izolovana iz korena rena i sintetički polimer (kiseli oblik poli-4-vinil-piridina funkcionalizovanog sa ferisulfatom). Promene kinetičkog stanja sistema izazvane prisustvom dodatih količina katalizatora se reflektuju na formu oscilograma, na vreme proteklo od početka reakcije do pojave prve oscilacije, na vreme proteklo od početka reakcije do kraja oscilatorne evolucije, broj oscilacija, srednjeg perioda oscilovanja i njihovu frekvenciju. Kako sva ova kinetička svojstva zavise od dodatih količina katalizatora na kompleksan ali analogan način, sličan reakcioni mehanizam se može očekivati u oba slučaja.",
publisher = "Međunarodni Institut za nauku o sinterovanju, Beograd",
journal = "Science of Sintering",
title = "The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide",
volume = "33",
number = "2",
pages = "107-115",
url = "https://hdl.handle.net/21.15107/rcub_farfar_301"
}

Pejić, N., Čupić, Ž., Anić, S., Vukojević, V.,& Kolar-Anić, L.. (2001). The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide. in Science of Sintering
Međunarodni Institut za nauku o sinterovanju, Beograd., 33(2), 107-115.
https://hdl.handle.net/21.15107/rcub_farfar_301

Pejić N, Čupić Ž, Anić S, Vukojević V, Kolar-Anić L. The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide. in Science of Sintering. 2001;33(2):107-115.
https://hdl.handle.net/21.15107/rcub_farfar_301 .

Pejić, Nataša, Čupić, Željko, Anić, Slobodan, Vukojević, Vladana, Kolar-Anić, Ljiljana, "The oscillatory Bray-Liebhafsky reaction as a matrix for analyzing enzyme and polymeric catalysts for hydrogen peroxide" in Science of Sintering, 33, no. 2 (2001):107-115,
https://hdl.handle.net/21.15107/rcub_farfar_301 .