@conference{
author = "Šesto, Sofija and Šesto, Sara and Krajnović, Dušanka",
year = "2022",
abstract = "Pharmacogenetics is a study of how people respond differently to drug therapy based
upon their genes (1). Available pharmacogenetics tests performed before starting therapy
allow each patient to receive the appropriate drug in an adequate dose, in accordance with
their genetic status (2). The aim of this research was to assess the attitudes of pharmacy
students about potential ethical issues that may be related to pharmacogenetics testing. This
descriptive study was conducted in the period from November to December 2019. Students
from all faculties of pharmacy in Serbia filled out a structured questionnaire of 35 questions.
A total of 256 respondents, predominantly female (83.8%), studying at the Faculty of
Pharmacy – University of Belgrade, participated in the research (88.7%). Most respondents
would consider doing a genetic test (78.5%). Of the ethical issues that may be associated
with pharmacogenetics testing, students cited patient privacy (27.0%) and data
confidentiality (22.7%), or both issues simultaneously (11.3%). Other reasons were forced
testing, stigmatization or racial problems (9.8%, 5.1%, 3.5%, respectively). Students of the
Faculty of Pharmacy in Belgrade more often recognized all five ethical problems in relation
to other faculties and this difference is high statistically significant (χ2 = 68.68, p <0.001).
The issue of patient privacy, race and forced testing were more often recognized by students
in lower years than in higher years of study (χ2 = 46.31, p <0.001). We conclude that
pharmacy students have a positive attitude towards pharmacogenetics and recognize ethical
issues related to pharmacogenetics and personalized medicine., Farmakogenetika se bavi genetičkim razlikama u metaboličkim putevima koji utiču na
odgovor pacijenta tokom primene lekova, u pogledu terapijskog dejstva i nuspojava (1).
Dostupni farmakogenetički testovi koji se rade pre započinjanja terapije omogućavaju
svakom pacijentu da dobije odgovarajući lek u adekvatnoj dozi, u skladu sa svojim
genetičkim statusom (2). Cilj ovog istraživanja je bila procena stavova studenata farmacije o
potencijalnim etičkim problemima koji mogu biti povezani sa farmakogenetičkim
testiranjem i predstavljati prepreku kliničkoj implementaciji personalizovane medicine. Ova
deskriptivna studija sprovedena je u periodu od novembra do decembra 2019 godine.
Studenti svih farmaceutskih fakulteta u Srbiji popunjavali su struktuirani upitnik od 35
pitanja. U istraživanju je učestvovalo ukupno 256 ispitanika, dominantno ženskog pola
(83,8%), koji studiraju na Farmaceutskom fakultetu – Univerziteta u Beogradu (88,7%).
Većina ispitanika razmotrila bi mogućnost da uradi genetički test (78,5%). Od etičkih
problema koji mogu biti povezani sa farmakogenetičkim testiranjem, studenti su najčešće
navodili privatnost (27,0%) i poverljivost podataka pacijenta (22,7%), ili oba problema
istovremeno (11,3%). Pored njih, drugi razlozi su bili i prisilno testiranje, stigmatizacija ili
rasni problemi (9,8%, 5,1%, 3,5%, redom). Studenti Farmaceutskog fakulteta u Beogradu
češće su prepoznavali svih pet etičkih problema u odnosu na ostale fakultete i ta razlika je
visoko statistički značajna (χ2 = 68.68, p < 0,001). Pitanje privatnosti pacijenata, rasu i
prisilno testiranje češće su prepoznavali studenti nižih u odnosu na više godine studija (χ2=
46,31, p<0,001). Zaključujemo da studenti farmacije imaju pozitivan stav prema
farmakogenetici i prepoznaju etičke probleme povezane sa farmakogenetikom i
personalizovanom medicinom.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Ethical issues related to pharmacogenetics: attitudes of pharmacy students, Etički problemi povezani sa farmakogenetikom: stavovi studenata farmacije",
volume = "72",
number = "4 suplement",
pages = "S319-S320",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4538"
}
