TY  - JOUR
AU  - Simachew, Yonas Mulat
AU  - Antonić, Tamara
AU  - Gojković, Tamara
AU  - Vladimirov, Sandra
AU  - Mihajlović, Marija
AU  - Vujčić, Sanja
AU  - Miloševski-Lomić, Gordana
AU  - Vekić, Jelena
AU  - Zeljković, Aleksandra
AU  - Spasojević-Kalimanovska, Vesna
AU  - Peco-Antić, Amira
AU  - Paripović, Dušan
AU  - Stefanović, Aleksandra
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4195
AB  - Introduction  The aim of this study was to investigate lipoprotein particle distributions and the likelihood of achieving cholesterol homeostasis in the remission phase of nephrotic syndrome (NS) in paediatric patients. We hypothesized that lipoprotein particle distributions moved toward less atherogenic profile and that cholesterol homeostasis was achieved. Materials and methods  Thirty-three children, 2 to 9 years old with NS were recruited. Blood sampling took place both in the acute phase and during remission. Serum low-density lipoprotein particles (LDL) and high-density lipoprotein particles (HDL) were separated using non-denaturing polyacrylamide gradient gel (3-31%) electrophoresis. Serum non-cholesterols sterols (NCSs), desmosterol, lathosterol, 7-dehydrocholesterol (7-DHC), campesterol and β-sitosterol were measured by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Results  All patients had desirable serum HDL cholesterol concentrations during remission. The dominant lipoprotein diameters and LDL subclass distribution did not change significantly during follow-up. In contrast, HDL lipoprotein particle distribution shifted towards larger particles. The absolute concentration of desmosterol was significantly lower during remission (P = 0.023). β-sitosterol concentration markedly increased during remission (P = 0.005). Desmosterol/β-sitosterol (P < 0.001) and 7-DHC/β-sitosterol (P = 0.005) ratios significantly declined during disease remission. Conclusions  Favourable changes in the serum lipid profiles, HDL particle subclass distribution and cholesterol metabolism in paediatric patients with NS during remission took place. For the first time, we found that cholesterol homeostasis changed in favour of increased cholesterol absorption during disease remission. Nevertheless, complete cholesterol homeostasis was not achieved during disease remission.
PB  - Croatian Society of Medical Biochemistry and Laboratory Medicine
T2  - Biochemia Medica
T1  - Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients
VL  - 32
IS  - 2
DO  - 10.11613/BM.2022.020706
ER  - 

@article{
author = "Simachew, Yonas Mulat and Antonić, Tamara and Gojković, Tamara and Vladimirov, Sandra and Mihajlović, Marija and Vujčić, Sanja and Miloševski-Lomić, Gordana and Vekić, Jelena and Zeljković, Aleksandra and Spasojević-Kalimanovska, Vesna and Peco-Antić, Amira and Paripović, Dušan and Stefanović, Aleksandra",
year = "2022",
abstract = "Introduction  The aim of this study was to investigate lipoprotein particle distributions and the likelihood of achieving cholesterol homeostasis in the remission phase of nephrotic syndrome (NS) in paediatric patients. We hypothesized that lipoprotein particle distributions moved toward less atherogenic profile and that cholesterol homeostasis was achieved. Materials and methods  Thirty-three children, 2 to 9 years old with NS were recruited. Blood sampling took place both in the acute phase and during remission. Serum low-density lipoprotein particles (LDL) and high-density lipoprotein particles (HDL) were separated using non-denaturing polyacrylamide gradient gel (3-31%) electrophoresis. Serum non-cholesterols sterols (NCSs), desmosterol, lathosterol, 7-dehydrocholesterol (7-DHC), campesterol and β-sitosterol were measured by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Results  All patients had desirable serum HDL cholesterol concentrations during remission. The dominant lipoprotein diameters and LDL subclass distribution did not change significantly during follow-up. In contrast, HDL lipoprotein particle distribution shifted towards larger particles. The absolute concentration of desmosterol was significantly lower during remission (P = 0.023). β-sitosterol concentration markedly increased during remission (P = 0.005). Desmosterol/β-sitosterol (P < 0.001) and 7-DHC/β-sitosterol (P = 0.005) ratios significantly declined during disease remission. Conclusions  Favourable changes in the serum lipid profiles, HDL particle subclass distribution and cholesterol metabolism in paediatric patients with NS during remission took place. For the first time, we found that cholesterol homeostasis changed in favour of increased cholesterol absorption during disease remission. Nevertheless, complete cholesterol homeostasis was not achieved during disease remission.",
publisher = "Croatian Society of Medical Biochemistry and Laboratory Medicine",
journal = "Biochemia Medica",
title = "Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients",
volume = "32",
number = "2",
doi = "10.11613/BM.2022.020706"
}

Simachew, Y. M., Antonić, T., Gojković, T., Vladimirov, S., Mihajlović, M., Vujčić, S., Miloševski-Lomić, G., Vekić, J., Zeljković, A., Spasojević-Kalimanovska, V., Peco-Antić, A., Paripović, D.,& Stefanović, A.. (2022). Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients. in Biochemia Medica
Croatian Society of Medical Biochemistry and Laboratory Medicine., 32(2).
https://doi.org/10.11613/BM.2022.020706

Simachew YM, Antonić T, Gojković T, Vladimirov S, Mihajlović M, Vujčić S, Miloševski-Lomić G, Vekić J, Zeljković A, Spasojević-Kalimanovska V, Peco-Antić A, Paripović D, Stefanović A. Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients. in Biochemia Medica. 2022;32(2).
doi:10.11613/BM.2022.020706 .

Simachew, Yonas Mulat, Antonić, Tamara, Gojković, Tamara, Vladimirov, Sandra, Mihajlović, Marija, Vujčić, Sanja, Miloševski-Lomić, Gordana, Vekić, Jelena, Zeljković, Aleksandra, Spasojević-Kalimanovska, Vesna, Peco-Antić, Amira, Paripović, Dušan, Stefanović, Aleksandra, "Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients" in Biochemia Medica, 32, no. 2 (2022),
https://doi.org/10.11613/BM.2022.020706 . .

TY  - CONF
AU  - Spasojević-Dimitrijeva, Brankica
AU  - Kotur-Stevuljević, Jelena
AU  - Đukić, Milan
AU  - Mitrović, Jadranka
AU  - Cvetković, Mirjana
AU  - Miloševski-Lomić, Gordana
AU  - Paripović, Dušan
AU  - Gojković, Ivan
AU  - Kostić, Mirjana
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3079
PB  - Springer, New York
C3  - Pediatric Nephrology
T1  - Acute kidney injury after gadolinium and iodinated-based contrast media exposure in children with normal renal function
VL  - 33
IS  - 10
SP  - 1840
EP  - 1841
DO  - 10.1007/s00467-018-4028-x
ER  - 

@conference{
author = "Spasojević-Dimitrijeva, Brankica and Kotur-Stevuljević, Jelena and Đukić, Milan and Mitrović, Jadranka and Cvetković, Mirjana and Miloševski-Lomić, Gordana and Paripović, Dušan and Gojković, Ivan and Kostić, Mirjana",
year = "2018",
publisher = "Springer, New York",
journal = "Pediatric Nephrology",
title = "Acute kidney injury after gadolinium and iodinated-based contrast media exposure in children with normal renal function",
volume = "33",
number = "10",
pages = "1840-1841",
doi = "10.1007/s00467-018-4028-x"
}

Spasojević-Dimitrijeva, B., Kotur-Stevuljević, J., Đukić, M., Mitrović, J., Cvetković, M., Miloševski-Lomić, G., Paripović, D., Gojković, I.,& Kostić, M.. (2018). Acute kidney injury after gadolinium and iodinated-based contrast media exposure in children with normal renal function. in Pediatric Nephrology
Springer, New York., 33(10), 1840-1841.
https://doi.org/10.1007/s00467-018-4028-x

Spasojević-Dimitrijeva B, Kotur-Stevuljević J, Đukić M, Mitrović J, Cvetković M, Miloševski-Lomić G, Paripović D, Gojković I, Kostić M. Acute kidney injury after gadolinium and iodinated-based contrast media exposure in children with normal renal function. in Pediatric Nephrology. 2018;33(10):1840-1841.
doi:10.1007/s00467-018-4028-x .

Spasojević-Dimitrijeva, Brankica, Kotur-Stevuljević, Jelena, Đukić, Milan, Mitrović, Jadranka, Cvetković, Mirjana, Miloševski-Lomić, Gordana, Paripović, Dušan, Gojković, Ivan, Kostić, Mirjana, "Acute kidney injury after gadolinium and iodinated-based contrast media exposure in children with normal renal function" in Pediatric Nephrology, 33, no. 10 (2018):1840-1841,
https://doi.org/10.1007/s00467-018-4028-x . .

TY  - JOUR
AU  - Paripović, Dušan
AU  - Kotur-Stevuljević, Jelena
AU  - Vukašinović, Aleksandra
AU  - Ilisić, Tamara
AU  - Miloševski-Lomić, Gordana
AU  - Peco-Antić, Amira
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3144
AB  - Oxidative stress seems to be an important link between obesity and cardiovascular disease. The aim of our study was to assess oxidative stress in obese patients stratified according to ambulatory blood pressure status and to determine independent predictors of abnormal left ventricular geometry.A cross-sectional study was conducted. A total of 113 obese participants referred for 24-h ambulatory blood pressure monitoring (ABPM) aged 9-19 years, and 29 healthy controls were enrolled. In addition to anthropometric and biochemical measurements, such as fasting serum levels of glucose, insulin, lipid profile, and oxidative biomarkers, ABPM and echocardiography were performed.According to ABPM results, obese subjects were split in two groups: 57 hypertensive and 56 normotensive. Both hypertensive and normotensive obese participants had higher levels of oxidative stress parameters (pro-oxidative/antioxidative balance and total oxidant status) compared with control group. Levels of superoxide anion (O-2(-)) and sulfhydryl groups were higher in obese hypertensive participants as compared to obese normotensive and control groups. Abnormal left ventricular geometry among obese participants was independently associated with O-2(-) (p = .006) and body mass index z score (p = .020), with no significant impact of gender, while age and systolic blood pressure exhibited interaction term for the outcome.The independent effect of oxidative mechanisms on left ventricular geometry appears to start in childhood. Oxidative stress occurs in obese adolescents prior to the development of sustained hypertension.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Scandinavian Journal of Clinical and Laboratory Investigation
T1  - The influence of oxidative stress on cardiac remodeling in obese adolescents
VL  - 78
IS  - 7-8
SP  - 595
EP  - 600
DO  - 10.1080/00365513.2018.1528504
ER  - 

@article{
author = "Paripović, Dušan and Kotur-Stevuljević, Jelena and Vukašinović, Aleksandra and Ilisić, Tamara and Miloševski-Lomić, Gordana and Peco-Antić, Amira",
year = "2018",
abstract = "Oxidative stress seems to be an important link between obesity and cardiovascular disease. The aim of our study was to assess oxidative stress in obese patients stratified according to ambulatory blood pressure status and to determine independent predictors of abnormal left ventricular geometry.A cross-sectional study was conducted. A total of 113 obese participants referred for 24-h ambulatory blood pressure monitoring (ABPM) aged 9-19 years, and 29 healthy controls were enrolled. In addition to anthropometric and biochemical measurements, such as fasting serum levels of glucose, insulin, lipid profile, and oxidative biomarkers, ABPM and echocardiography were performed.According to ABPM results, obese subjects were split in two groups: 57 hypertensive and 56 normotensive. Both hypertensive and normotensive obese participants had higher levels of oxidative stress parameters (pro-oxidative/antioxidative balance and total oxidant status) compared with control group. Levels of superoxide anion (O-2(-)) and sulfhydryl groups were higher in obese hypertensive participants as compared to obese normotensive and control groups. Abnormal left ventricular geometry among obese participants was independently associated with O-2(-) (p = .006) and body mass index z score (p = .020), with no significant impact of gender, while age and systolic blood pressure exhibited interaction term for the outcome.The independent effect of oxidative mechanisms on left ventricular geometry appears to start in childhood. Oxidative stress occurs in obese adolescents prior to the development of sustained hypertension.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Scandinavian Journal of Clinical and Laboratory Investigation",
title = "The influence of oxidative stress on cardiac remodeling in obese adolescents",
volume = "78",
number = "7-8",
pages = "595-600",
doi = "10.1080/00365513.2018.1528504"
}

Paripović, D., Kotur-Stevuljević, J., Vukašinović, A., Ilisić, T., Miloševski-Lomić, G.,& Peco-Antić, A.. (2018). The influence of oxidative stress on cardiac remodeling in obese adolescents. in Scandinavian Journal of Clinical and Laboratory Investigation
Taylor & Francis Ltd, Abingdon., 78(7-8), 595-600.
https://doi.org/10.1080/00365513.2018.1528504

Paripović D, Kotur-Stevuljević J, Vukašinović A, Ilisić T, Miloševski-Lomić G, Peco-Antić A. The influence of oxidative stress on cardiac remodeling in obese adolescents. in Scandinavian Journal of Clinical and Laboratory Investigation. 2018;78(7-8):595-600.
doi:10.1080/00365513.2018.1528504 .

Paripović, Dušan, Kotur-Stevuljević, Jelena, Vukašinović, Aleksandra, Ilisić, Tamara, Miloševski-Lomić, Gordana, Peco-Antić, Amira, "The influence of oxidative stress on cardiac remodeling in obese adolescents" in Scandinavian Journal of Clinical and Laboratory Investigation, 78, no. 7-8 (2018):595-600,
https://doi.org/10.1080/00365513.2018.1528504 . .

TY  - JOUR
AU  - Bekhet, Osama H.
AU  - Vekić, Jelena
AU  - Zeljković, Aleksandra
AU  - Paripović, Dušan
AU  - Gojković, Tamara
AU  - Janać, Jelena
AU  - Spasojević-Kalimanovska, Vesna
AU  - Peco-Antić, Amira
AU  - Miloševski-Lomić, Gordana
AU  - Jelić-Ivanović, Zorana
AU  - Stefanović, Aleksandra
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2845
AB  - N Background/aim: Juvenile obesity is associated with several metabolic abnormalities, one of them being atherogenic dyslipidemia. Suboptimal fetal growth is associated with obesity risk in childhood, but also with increased rate of metabolic diseases in later life. This study investigated associations of neonatal data (Apgar score, birth weight and birth length) with low-density lipoprotein and high-density lipoprotein (LDL and HDL) subclasses in a group of obese children, as well as a possible impact of breastfeeding duration on obesity-associated lipoprotein subclasses distributions. Materials and methods: We included 42 obese children, aged 14.2 +/- 2.1 years. LDL and HDL subfractions were separated by gradient gel electrophoresis and biochemical parameters were assessed by routine methods. Results: Compared with obese children with Apgar >= 9, the group with Apgar  lt  9 had significantly higher percentages of small, dense LDL particles (P  lt  0.05), due to reduced LDL I (P  lt  0.01) and increased LDL III subclasses (P  lt  0.05). Birth weight was positively associated with the proportions of LDL I particles (P  lt  0.001), whereas birth height positively correlated with the amount of HDL 2b subclasses (P  lt  0.05). The group of never or less than 3 months breastfed children had significantly smaller LDL size (P  lt  0.01) and lower proportion of HDL 2a particles (P  lt  0.05) than their >= 3 months breastfed peers. Conclusion: The results showed significant associations of neonatal characteristics with LDL and HDL particle distributions in obese children. In addition, our results point toward positive aspects of longer breastfeeding duration on lipoprotein particle distributions in obese children.
PB  - Tubitak Scientific & Technical Research Council Turkey, Ankara
T2  - Upsala Journal of Medical Sciences
T1  - Associations of Apgar score and size at birth with lipoprotein subclasses in juvenile obesity
VL  - 47
IS  - 6
SP  - 1804
EP  - 1812
DO  - 10.3906/sag-1702-164
ER  - 

@article{
author = "Bekhet, Osama H. and Vekić, Jelena and Zeljković, Aleksandra and Paripović, Dušan and Gojković, Tamara and Janać, Jelena and Spasojević-Kalimanovska, Vesna and Peco-Antić, Amira and Miloševski-Lomić, Gordana and Jelić-Ivanović, Zorana and Stefanović, Aleksandra",
year = "2017",
abstract = "N Background/aim: Juvenile obesity is associated with several metabolic abnormalities, one of them being atherogenic dyslipidemia. Suboptimal fetal growth is associated with obesity risk in childhood, but also with increased rate of metabolic diseases in later life. This study investigated associations of neonatal data (Apgar score, birth weight and birth length) with low-density lipoprotein and high-density lipoprotein (LDL and HDL) subclasses in a group of obese children, as well as a possible impact of breastfeeding duration on obesity-associated lipoprotein subclasses distributions. Materials and methods: We included 42 obese children, aged 14.2 +/- 2.1 years. LDL and HDL subfractions were separated by gradient gel electrophoresis and biochemical parameters were assessed by routine methods. Results: Compared with obese children with Apgar >= 9, the group with Apgar  lt  9 had significantly higher percentages of small, dense LDL particles (P  lt  0.05), due to reduced LDL I (P  lt  0.01) and increased LDL III subclasses (P  lt  0.05). Birth weight was positively associated with the proportions of LDL I particles (P  lt  0.001), whereas birth height positively correlated with the amount of HDL 2b subclasses (P  lt  0.05). The group of never or less than 3 months breastfed children had significantly smaller LDL size (P  lt  0.01) and lower proportion of HDL 2a particles (P  lt  0.05) than their >= 3 months breastfed peers. Conclusion: The results showed significant associations of neonatal characteristics with LDL and HDL particle distributions in obese children. In addition, our results point toward positive aspects of longer breastfeeding duration on lipoprotein particle distributions in obese children.",
publisher = "Tubitak Scientific & Technical Research Council Turkey, Ankara",
journal = "Upsala Journal of Medical Sciences",
title = "Associations of Apgar score and size at birth with lipoprotein subclasses in juvenile obesity",
volume = "47",
number = "6",
pages = "1804-1812",
doi = "10.3906/sag-1702-164"
}

Bekhet, O. H., Vekić, J., Zeljković, A., Paripović, D., Gojković, T., Janać, J., Spasojević-Kalimanovska, V., Peco-Antić, A., Miloševski-Lomić, G., Jelić-Ivanović, Z.,& Stefanović, A.. (2017). Associations of Apgar score and size at birth with lipoprotein subclasses in juvenile obesity. in Upsala Journal of Medical Sciences
Tubitak Scientific & Technical Research Council Turkey, Ankara., 47(6), 1804-1812.
https://doi.org/10.3906/sag-1702-164

Bekhet OH, Vekić J, Zeljković A, Paripović D, Gojković T, Janać J, Spasojević-Kalimanovska V, Peco-Antić A, Miloševski-Lomić G, Jelić-Ivanović Z, Stefanović A. Associations of Apgar score and size at birth with lipoprotein subclasses in juvenile obesity. in Upsala Journal of Medical Sciences. 2017;47(6):1804-1812.
doi:10.3906/sag-1702-164 .

Bekhet, Osama H., Vekić, Jelena, Zeljković, Aleksandra, Paripović, Dušan, Gojković, Tamara, Janać, Jelena, Spasojević-Kalimanovska, Vesna, Peco-Antić, Amira, Miloševski-Lomić, Gordana, Jelić-Ivanović, Zorana, Stefanović, Aleksandra, "Associations of Apgar score and size at birth with lipoprotein subclasses in juvenile obesity" in Upsala Journal of Medical Sciences, 47, no. 6 (2017):1804-1812,
https://doi.org/10.3906/sag-1702-164 . .

TY  - JOUR
AU  - Spasojević-Dimitrijeva, Brankica
AU  - Kotur-Stevuljević, Jelena
AU  - Dukić, Milan
AU  - Paripović, Dušan
AU  - Miloševski-Lomić, Gordana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Pavicević, Polina
AU  - Mitrović, Jadranka
AU  - Kostić, Mirjana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2793
AB  - Background: New renal biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) show promise in early diagnosis of contrast media induced acute kidney injury (CI-AKI). The purpose of our study was to compare the subclinical nephrotoxicity (a condition without changes in standard renal biomarkers) of gadolinium-based contrast media (Gd-DTPA, gadopentetate dimeglumine) and iodinated-based contrast media (iopromide) in pediatric patients with normal kidney function. Material/Methods: The first group (n=58) of patients included in the study were undergoing angiography with iopromide, and the second group (n=65) were undergoing magnetic resonance (MR) angiography/urography with Gd-DTPA administration. The concentrations of NGAL and KIM-1 were measured four times in the urine (pre-contrast, then at four hours, 24 hours, and 48 hours after contrast administration), and serum NGAL was measured at 0 (base-line), 24 hours, and 48 hours after contrast exposure. Results: After 24 hours, serum NGAL increase of >= 25% was noticed in 32.6% of the patients in the iopromide group and in 25.45% of the patients in the gadolinium group, with significantly higher average percent of this increase in first group (62.23% vs. 36.44%, p=0.002). In the Gd-DTPA group, we observed a statistically significant increase in urinary KIM-1 24 hours after the procedure. Normalized urinary KIM-1, 24 hours after contrast exposure, was a better predictive factor for CI-AKI than other biomarkers (AUC 0.757, cut off 214 pg/mg, sensitivity 83.3%, specificity 54.2%, p=0.035). Conclusions: In children with normal renal function, exposure to iodinated-based and gadolinium-based media might lead to subclinical nephrotoxicity, which could be detected using serum NGAL and urinary KIM-1.
PB  - Int Scientific Information, Inc, Melville
T2  - Medical Science Monitor
T1  - Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio
VL  - 23
DO  - 10.12659/MSM.903255
ER  - 

@article{
author = "Spasojević-Dimitrijeva, Brankica and Kotur-Stevuljević, Jelena and Dukić, Milan and Paripović, Dušan and Miloševski-Lomić, Gordana and Spasojević-Kalimanovska, Vesna and Pavicević, Polina and Mitrović, Jadranka and Kostić, Mirjana",
year = "2017",
abstract = "Background: New renal biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) show promise in early diagnosis of contrast media induced acute kidney injury (CI-AKI). The purpose of our study was to compare the subclinical nephrotoxicity (a condition without changes in standard renal biomarkers) of gadolinium-based contrast media (Gd-DTPA, gadopentetate dimeglumine) and iodinated-based contrast media (iopromide) in pediatric patients with normal kidney function. Material/Methods: The first group (n=58) of patients included in the study were undergoing angiography with iopromide, and the second group (n=65) were undergoing magnetic resonance (MR) angiography/urography with Gd-DTPA administration. The concentrations of NGAL and KIM-1 were measured four times in the urine (pre-contrast, then at four hours, 24 hours, and 48 hours after contrast administration), and serum NGAL was measured at 0 (base-line), 24 hours, and 48 hours after contrast exposure. Results: After 24 hours, serum NGAL increase of >= 25% was noticed in 32.6% of the patients in the iopromide group and in 25.45% of the patients in the gadolinium group, with significantly higher average percent of this increase in first group (62.23% vs. 36.44%, p=0.002). In the Gd-DTPA group, we observed a statistically significant increase in urinary KIM-1 24 hours after the procedure. Normalized urinary KIM-1, 24 hours after contrast exposure, was a better predictive factor for CI-AKI than other biomarkers (AUC 0.757, cut off 214 pg/mg, sensitivity 83.3%, specificity 54.2%, p=0.035). Conclusions: In children with normal renal function, exposure to iodinated-based and gadolinium-based media might lead to subclinical nephrotoxicity, which could be detected using serum NGAL and urinary KIM-1.",
publisher = "Int Scientific Information, Inc, Melville",
journal = "Medical Science Monitor",
title = "Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio",
volume = "23",
doi = "10.12659/MSM.903255"
}

Spasojević-Dimitrijeva, B., Kotur-Stevuljević, J., Dukić, M., Paripović, D., Miloševski-Lomić, G., Spasojević-Kalimanovska, V., Pavicević, P., Mitrović, J.,& Kostić, M.. (2017). Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio. in Medical Science Monitor
Int Scientific Information, Inc, Melville., 23.
https://doi.org/10.12659/MSM.903255

Spasojević-Dimitrijeva B, Kotur-Stevuljević J, Dukić M, Paripović D, Miloševski-Lomić G, Spasojević-Kalimanovska V, Pavicević P, Mitrović J, Kostić M. Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio. in Medical Science Monitor. 2017;23.
doi:10.12659/MSM.903255 .

Spasojević-Dimitrijeva, Brankica, Kotur-Stevuljević, Jelena, Dukić, Milan, Paripović, Dušan, Miloševski-Lomić, Gordana, Spasojević-Kalimanovska, Vesna, Pavicević, Polina, Mitrović, Jadranka, Kostić, Mirjana, "Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio" in Medical Science Monitor, 23 (2017),
https://doi.org/10.12659/MSM.903255 . .

TY  - JOUR
AU  - Ristovski-Kornić, Danijela
AU  - Stefanović, Aleksandra
AU  - Kotur-Stevuljević, Jelena
AU  - Zeljković, Aleksandra
AU  - Spasojević-Kalimanovska, Vesna
AU  - Vekić, Jelena
AU  - Miljković, Milica
AU  - Paripović, Dušan
AU  - Peco-Antić, Amira
AU  - Jelić-Ivanović, Zorana
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2956
AB  - Background: The aim of this study was to explore oxidative stress status, especially the enzyme myeloperoxidase in children with end-stage renal disease. Also, we investigated possible associations between the atherogenic index of plasma and these parameters. Methods: Lipid status parameters, oxidative stress status parameters, and myeloperoxidase concentration were measured in the sera of 20 children in the last stage of chronic renal disease (ESRD) and 35 healthy children of matching age and sex. The Atherogenic Index of Plasma (AIP) was calculated according to the appropriate equation. Results: We did not find any significant differences in myeloperoxidase concentrations between the investigated groups (p = 0.394). Oxidative stress parameters were, however, significantly higher in the patient group (p  lt  0.001), as well as the atherogenic index of plasma (p  lt  0.001). Myelo per oxidase concentration and advanced oxidation protein product (AOPP) concentration were independently associated with increased AIP in the patient group (p  lt  0.05). Conclusions: Changes in AIP in children with ERSD are associated with the oxidative stress status and myeloper oxidase concentration.
PB  - Društvo medicinskih biohemičara Srbije, Beograd i Versita
T2  - Journal of Medical Biochemistry
T1  - Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease
VL  - 36
IS  - 1
SP  - 23
EP  - 31
DO  - 10.1515/jomb-2016-0027
ER  - 

@article{
author = "Ristovski-Kornić, Danijela and Stefanović, Aleksandra and Kotur-Stevuljević, Jelena and Zeljković, Aleksandra and Spasojević-Kalimanovska, Vesna and Vekić, Jelena and Miljković, Milica and Paripović, Dušan and Peco-Antić, Amira and Jelić-Ivanović, Zorana",
year = "2017",
abstract = "Background: The aim of this study was to explore oxidative stress status, especially the enzyme myeloperoxidase in children with end-stage renal disease. Also, we investigated possible associations between the atherogenic index of plasma and these parameters. Methods: Lipid status parameters, oxidative stress status parameters, and myeloperoxidase concentration were measured in the sera of 20 children in the last stage of chronic renal disease (ESRD) and 35 healthy children of matching age and sex. The Atherogenic Index of Plasma (AIP) was calculated according to the appropriate equation. Results: We did not find any significant differences in myeloperoxidase concentrations between the investigated groups (p = 0.394). Oxidative stress parameters were, however, significantly higher in the patient group (p  lt  0.001), as well as the atherogenic index of plasma (p  lt  0.001). Myelo per oxidase concentration and advanced oxidation protein product (AOPP) concentration were independently associated with increased AIP in the patient group (p  lt  0.05). Conclusions: Changes in AIP in children with ERSD are associated with the oxidative stress status and myeloper oxidase concentration.",
publisher = "Društvo medicinskih biohemičara Srbije, Beograd i Versita",
journal = "Journal of Medical Biochemistry",
title = "Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease",
volume = "36",
number = "1",
pages = "23-31",
doi = "10.1515/jomb-2016-0027"
}

Ristovski-Kornić, D., Stefanović, A., Kotur-Stevuljević, J., Zeljković, A., Spasojević-Kalimanovska, V., Vekić, J., Miljković, M., Paripović, D., Peco-Antić, A.,& Jelić-Ivanović, Z.. (2017). Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease. in Journal of Medical Biochemistry
Društvo medicinskih biohemičara Srbije, Beograd i Versita., 36(1), 23-31.
https://doi.org/10.1515/jomb-2016-0027

Ristovski-Kornić D, Stefanović A, Kotur-Stevuljević J, Zeljković A, Spasojević-Kalimanovska V, Vekić J, Miljković M, Paripović D, Peco-Antić A, Jelić-Ivanović Z. Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease. in Journal of Medical Biochemistry. 2017;36(1):23-31.
doi:10.1515/jomb-2016-0027 .

Ristovski-Kornić, Danijela, Stefanović, Aleksandra, Kotur-Stevuljević, Jelena, Zeljković, Aleksandra, Spasojević-Kalimanovska, Vesna, Vekić, Jelena, Miljković, Milica, Paripović, Dušan, Peco-Antić, Amira, Jelić-Ivanović, Zorana, "Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease" in Journal of Medical Biochemistry, 36, no. 1 (2017):23-31,
https://doi.org/10.1515/jomb-2016-0027 . .

TY  - JOUR
AU  - Stefanović, Aleksandra
AU  - Ristovski-Kornić, Danijela
AU  - Kotur-Stevuljević, Jelena
AU  - Spasojević-Kalimanovska, Vesna
AU  - Vekić, Jelena
AU  - Miljković, Milica
AU  - Paripović, Dušan
AU  - Peco-Antić, Amira
AU  - Jelić-Ivanović, Zorana
AU  - Zeljković, Aleksandra
PY  - 2017
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2815
AB  - Background: Unfavorable lipid profile presents one of most important risk factor for cardiovascular disease in renal pathology. Myeloperoxidase (MPO) as enzyme which oxidizes lipoproteins and paraoxonase1 (PON1) as anti-oxidative enzyme have been involved in pathogenesis of cardiovascular disease. In the present study we sought to assess oxidative stress status, lipoprotein subclasses distribution as well as functionality of high density lipoprotein (HDL) trough MPO/PON1 ratio in children with chronic kidney disease (CKD) and children after renal transplantation. Methods: PON1 activity and oxidative stress parameters were measured spectrophotometrically, while MPO concentration was determined using immunoassay. Separation of lipoprotein subclasses was performed by vertical gradient gel electrophoresis in 19 children with different stage of CKD and 19 post-transplantation patients (PT). Results: CKD patients had increased MPO/PON1 ratio and higher prevalence of smaller HDL subclasses when compared to PT subjects. Also, there was a significant positive correlation between MPO level and MPO/PON1 ratio with relative proportion of smaller HDL subclasses. Conclusions: Children with CKD have impaired HDL distribution that is improved after kidney transplantation. Since that measurement of HDL distribution and functionality arenot routinely available, MPO/PON1 ratio may be useful marker that could provide necessary information.
PB  - Društvo medicinskih biohemičara Srbije, Beograd i Versita
T2  - Journal of Medical Biochemistry
T1  - Alterations of HDL Particles in Children with End-Stage Renal Disease
VL  - 36
IS  - 4
SP  - 358
EP  - 365
DO  - 10.1515/jomb-2017-0019
ER  - 

@article{
author = "Stefanović, Aleksandra and Ristovski-Kornić, Danijela and Kotur-Stevuljević, Jelena and Spasojević-Kalimanovska, Vesna and Vekić, Jelena and Miljković, Milica and Paripović, Dušan and Peco-Antić, Amira and Jelić-Ivanović, Zorana and Zeljković, Aleksandra",
year = "2017",
abstract = "Background: Unfavorable lipid profile presents one of most important risk factor for cardiovascular disease in renal pathology. Myeloperoxidase (MPO) as enzyme which oxidizes lipoproteins and paraoxonase1 (PON1) as anti-oxidative enzyme have been involved in pathogenesis of cardiovascular disease. In the present study we sought to assess oxidative stress status, lipoprotein subclasses distribution as well as functionality of high density lipoprotein (HDL) trough MPO/PON1 ratio in children with chronic kidney disease (CKD) and children after renal transplantation. Methods: PON1 activity and oxidative stress parameters were measured spectrophotometrically, while MPO concentration was determined using immunoassay. Separation of lipoprotein subclasses was performed by vertical gradient gel electrophoresis in 19 children with different stage of CKD and 19 post-transplantation patients (PT). Results: CKD patients had increased MPO/PON1 ratio and higher prevalence of smaller HDL subclasses when compared to PT subjects. Also, there was a significant positive correlation between MPO level and MPO/PON1 ratio with relative proportion of smaller HDL subclasses. Conclusions: Children with CKD have impaired HDL distribution that is improved after kidney transplantation. Since that measurement of HDL distribution and functionality arenot routinely available, MPO/PON1 ratio may be useful marker that could provide necessary information.",
publisher = "Društvo medicinskih biohemičara Srbije, Beograd i Versita",
journal = "Journal of Medical Biochemistry",
title = "Alterations of HDL Particles in Children with End-Stage Renal Disease",
volume = "36",
number = "4",
pages = "358-365",
doi = "10.1515/jomb-2017-0019"
}

Stefanović, A., Ristovski-Kornić, D., Kotur-Stevuljević, J., Spasojević-Kalimanovska, V., Vekić, J., Miljković, M., Paripović, D., Peco-Antić, A., Jelić-Ivanović, Z.,& Zeljković, A.. (2017). Alterations of HDL Particles in Children with End-Stage Renal Disease. in Journal of Medical Biochemistry
Društvo medicinskih biohemičara Srbije, Beograd i Versita., 36(4), 358-365.
https://doi.org/10.1515/jomb-2017-0019

Stefanović A, Ristovski-Kornić D, Kotur-Stevuljević J, Spasojević-Kalimanovska V, Vekić J, Miljković M, Paripović D, Peco-Antić A, Jelić-Ivanović Z, Zeljković A. Alterations of HDL Particles in Children with End-Stage Renal Disease. in Journal of Medical Biochemistry. 2017;36(4):358-365.
doi:10.1515/jomb-2017-0019 .

Stefanović, Aleksandra, Ristovski-Kornić, Danijela, Kotur-Stevuljević, Jelena, Spasojević-Kalimanovska, Vesna, Vekić, Jelena, Miljković, Milica, Paripović, Dušan, Peco-Antić, Amira, Jelić-Ivanović, Zorana, Zeljković, Aleksandra, "Alterations of HDL Particles in Children with End-Stage Renal Disease" in Journal of Medical Biochemistry, 36, no. 4 (2017):358-365,
https://doi.org/10.1515/jomb-2017-0019 . .

TY  - JOUR
AU  - Bekhet, Osama H.
AU  - Zeljković, Aleksandra
AU  - Vekić, Jelena
AU  - Paripović, Dušan
AU  - Janać, Jelena
AU  - Joksić, Jelena
AU  - Gojković, Tamara
AU  - Spasojević-Kalimanovska, Vesna
AU  - Peco-Antić, Amira
AU  - Miloševski-Lomić, Gordana
AU  - Jelić-Ivanović, Zorana
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2727
AB  - Background: Obesity-related childhood hypertension is associated with disturbances of serum lipids, but less is known about distribution of lipoprotein subclasses and activities of proteins involved in reverse cholesterol transport in hypertensive obese children. Our objective was to determine low-density lipoprotein (LDL) and high-density lipoprotein (HDL) subclasses distribution and activities of lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP) in hypertensive and non-hypertensive obese children.Methods: A total of 40 hypertensive and 25 non-hypertensive obese children were enrolled. Lipoprotein subclasses were assessed by polyacrylamide gradient gel electrophoresis. LCAT and CETP activities were determined as a rate of formation and a rate of transfer of cholesteryl esters.Results: Despite of comparable values of serum lipid parameters, a shift toward smaller LDL and HDL subclasses was observed in hypertensive compared to normotensive obese children. Activities of LCAT were similar, but proatherogenic CETP activities were significantly higher in the hypertensive group (p= 0.036). LCAT/net CETP ratio inversely correlated with relative proportion of small, dense LDL particles ( =-0.423; p= 0.025) in the group with hypertension.Conclusions: The results of our study demonstrated a tendency toward altered distribution of lipoprotein subclasses in favor of more proatherogenic particles in childhood hypertension. Also, hypertensive obese children had increased proatherogenic CETP activity.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Scandinavian Journal of Clinical and Laboratory Investigation
T1  - Hypertension, lipoprotein subclasses and lipid transfer proteins in obese children and adolescents
VL  - 76
IS  - 6
SP  - 472
EP  - 478
DO  - 10.1080/00365513.2016.1201849
ER  - 

@article{
author = "Bekhet, Osama H. and Zeljković, Aleksandra and Vekić, Jelena and Paripović, Dušan and Janać, Jelena and Joksić, Jelena and Gojković, Tamara and Spasojević-Kalimanovska, Vesna and Peco-Antić, Amira and Miloševski-Lomić, Gordana and Jelić-Ivanović, Zorana",
year = "2016",
abstract = "Background: Obesity-related childhood hypertension is associated with disturbances of serum lipids, but less is known about distribution of lipoprotein subclasses and activities of proteins involved in reverse cholesterol transport in hypertensive obese children. Our objective was to determine low-density lipoprotein (LDL) and high-density lipoprotein (HDL) subclasses distribution and activities of lecithin:cholesterol acyltransferase (LCAT) and cholesteryl ester transfer protein (CETP) in hypertensive and non-hypertensive obese children.Methods: A total of 40 hypertensive and 25 non-hypertensive obese children were enrolled. Lipoprotein subclasses were assessed by polyacrylamide gradient gel electrophoresis. LCAT and CETP activities were determined as a rate of formation and a rate of transfer of cholesteryl esters.Results: Despite of comparable values of serum lipid parameters, a shift toward smaller LDL and HDL subclasses was observed in hypertensive compared to normotensive obese children. Activities of LCAT were similar, but proatherogenic CETP activities were significantly higher in the hypertensive group (p= 0.036). LCAT/net CETP ratio inversely correlated with relative proportion of small, dense LDL particles ( =-0.423; p= 0.025) in the group with hypertension.Conclusions: The results of our study demonstrated a tendency toward altered distribution of lipoprotein subclasses in favor of more proatherogenic particles in childhood hypertension. Also, hypertensive obese children had increased proatherogenic CETP activity.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Scandinavian Journal of Clinical and Laboratory Investigation",
title = "Hypertension, lipoprotein subclasses and lipid transfer proteins in obese children and adolescents",
volume = "76",
number = "6",
pages = "472-478",
doi = "10.1080/00365513.2016.1201849"
}

Bekhet, O. H., Zeljković, A., Vekić, J., Paripović, D., Janać, J., Joksić, J., Gojković, T., Spasojević-Kalimanovska, V., Peco-Antić, A., Miloševski-Lomić, G.,& Jelić-Ivanović, Z.. (2016). Hypertension, lipoprotein subclasses and lipid transfer proteins in obese children and adolescents. in Scandinavian Journal of Clinical and Laboratory Investigation
Taylor & Francis Ltd, Abingdon., 76(6), 472-478.
https://doi.org/10.1080/00365513.2016.1201849

Bekhet OH, Zeljković A, Vekić J, Paripović D, Janać J, Joksić J, Gojković T, Spasojević-Kalimanovska V, Peco-Antić A, Miloševski-Lomić G, Jelić-Ivanović Z. Hypertension, lipoprotein subclasses and lipid transfer proteins in obese children and adolescents. in Scandinavian Journal of Clinical and Laboratory Investigation. 2016;76(6):472-478.
doi:10.1080/00365513.2016.1201849 .

Bekhet, Osama H., Zeljković, Aleksandra, Vekić, Jelena, Paripović, Dušan, Janać, Jelena, Joksić, Jelena, Gojković, Tamara, Spasojević-Kalimanovska, Vesna, Peco-Antić, Amira, Miloševski-Lomić, Gordana, Jelić-Ivanović, Zorana, "Hypertension, lipoprotein subclasses and lipid transfer proteins in obese children and adolescents" in Scandinavian Journal of Clinical and Laboratory Investigation, 76, no. 6 (2016):472-478,
https://doi.org/10.1080/00365513.2016.1201849 . .

TY  - JOUR
AU  - Pavlović, Branko
AU  - Milosavljević, Jovana
AU  - Zeljković, Aleksandra
AU  - Vekić, Jelena
AU  - Joksić, Jelena
AU  - Sopić, Miron
AU  - Spasojević-Kalimanovska, Vesna
AU  - Paripović, Dušan
AU  - Peco-Antić, Amira
AU  - Miloševski-Lomić, Gordana
AU  - Jelić-Ivanović, Zorana
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2514
AB  - Introduction: Childhood obesity is related to cardiovascular diseases and diabetes mellitus type 2 in later life. Resistin, an adipokine primarily secreted by monocytes and tissue macrophages in humans, is considered to be associated with these conditions. The Aim: To examine the correlations between resistin concentration and anthropometric parameters, lipid status, inflammatory markers and parameters of insulin resistance in obese children and adolescents. Material and Methods: The study included 66 patients (40 boys, 26 girls), which underwent anthropometric measuring and laboratory testing (glucose level, total cholesterol, high-density lipoprotein cholesterol (HDL-cholesterol), low-density lipoprotein cholesterol (LDL-cholesterol), triglycerides, uric acid, high-sensitivity C-reactive protein (hsCRP) and glycosylated hemoglobin (HbA1c). Insulin resistance was estimated with HOMA-IR (homeostasis model assessment of insulin resistance). Results: We determined that 63.3% of our patients had dyslipidemia, while hsCRP and uric acid levels suggested an ongoing inflammation. We established that there was a correlation between resistin concentration and waist to hip ratio (WHR) (r=0.294, p lt 0.05), as well as between resistin concentration and HOMA-IR (r=0.293, p lt 0.05). Also, uric acid levels correlated with obesity parameters. While comparing parameters by gender we found a significant difference in height (p lt 0.01), WHR (p lt 0.001), uric acid levels (p lt 0.01) and HOMA-IR (p lt 0.01). Conclusion: Our results show a link between obesity, inflammation and dyslipidemia in children and adolescents. In the future, resistin could become a significant clinical marker for evaluation of cardiometabolic risk.
AB  - Uvod: Gojaznost u dečjem uzrastu se povezuje sa razvojem kardiovaskularnih bolesti i tipa 2 dijabetes melitusa u kasnijem dobu. Smatra se da je rezistin, adipokin kojeg u humanom organizumu luče monociti i tkivne makrofage, povezan sa ovim poremećajima. Cilj: Ispitati povezanost koncentracije rezistina kod gojazne dece i adolescenata sa antropometrijskim parametrima gojaznosti, lipidnim statusom, inflamatornim markerima i parametrima insulinske rezistencije. Materijal i metode: U istraživanju je učestvovalo 66 ispitanika (40 dečaka, 26 devojčica) kojima su izvršena antropometrijska merenja i laboratorijska ispitivanja (koncentracije glukoze, ukupnog holesterola, holesterola u česticama lipoproteina visoke gustine (eng. high-density lipoprotein, HDL) i niske gustine (eng. low-density lipoprotein, LDL), triglicerida, mokraćne kiseline, visokoosetljivog C-reaktivnog proteina (high-sensitivity C-reactive protein; hsCRP) i glikoziliranog hemoglobina (HbA1c)). Insulinska rezistencija je procenjena na osnovu modela za izračunavanje indeksa insulinske rezistencije (eng. homeostasis model assessment of insulin resistance; HOMA-IR). Rezultati: Kod 63,3% ispitanika utvrdili smo prisutnu dislipidemiju, a dobijene vrednosti hsCRP i mokraćne kiseline ukazuju na prisustvo inflamacije. Utvrdili smo korelaciju između koncentracije rezistina i odnosa obima struka i kukova (r=0,294, p lt 0,05) i između koncentracije rezistina i HOMA-IR (r=0,293, p lt 0,05). Ustanovili smo povezanost koncentracije mokraćne kiseline i parametara gojaznosti. Upoređivanjem parametara između polova, značajna razlika postoji u telesnoj visini (p lt 0,01), odnosu obima struka i kukova (p lt 0,001), mokraćnoj kiselini (p lt 0,01) i HOMA-IR (p lt 0,01). Zaključak: Naši rezultati ukazuju na povezanost gojaznosti, inflamacije i dislipidemije kod dece i adolescenata. Rezistin bi u budućnosti mogao biti značajan za procenu kardiometaboličkog rizika u ovoj populaciji.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Resistin, inflammation and dyslipidemia in obese children and adolescents
T1  - Rezistin, inflamacija i dislipidemija kod gojazne dece i adolescenata
VL  - 65
IS  - 2
SP  - 115
EP  - 128
DO  - 10.5937/arhfarm1502115P
ER  - 

@article{
author = "Pavlović, Branko and Milosavljević, Jovana and Zeljković, Aleksandra and Vekić, Jelena and Joksić, Jelena and Sopić, Miron and Spasojević-Kalimanovska, Vesna and Paripović, Dušan and Peco-Antić, Amira and Miloševski-Lomić, Gordana and Jelić-Ivanović, Zorana",
year = "2015",
abstract = "Introduction: Childhood obesity is related to cardiovascular diseases and diabetes mellitus type 2 in later life. Resistin, an adipokine primarily secreted by monocytes and tissue macrophages in humans, is considered to be associated with these conditions. The Aim: To examine the correlations between resistin concentration and anthropometric parameters, lipid status, inflammatory markers and parameters of insulin resistance in obese children and adolescents. Material and Methods: The study included 66 patients (40 boys, 26 girls), which underwent anthropometric measuring and laboratory testing (glucose level, total cholesterol, high-density lipoprotein cholesterol (HDL-cholesterol), low-density lipoprotein cholesterol (LDL-cholesterol), triglycerides, uric acid, high-sensitivity C-reactive protein (hsCRP) and glycosylated hemoglobin (HbA1c). Insulin resistance was estimated with HOMA-IR (homeostasis model assessment of insulin resistance). Results: We determined that 63.3% of our patients had dyslipidemia, while hsCRP and uric acid levels suggested an ongoing inflammation. We established that there was a correlation between resistin concentration and waist to hip ratio (WHR) (r=0.294, p lt 0.05), as well as between resistin concentration and HOMA-IR (r=0.293, p lt 0.05). Also, uric acid levels correlated with obesity parameters. While comparing parameters by gender we found a significant difference in height (p lt 0.01), WHR (p lt 0.001), uric acid levels (p lt 0.01) and HOMA-IR (p lt 0.01). Conclusion: Our results show a link between obesity, inflammation and dyslipidemia in children and adolescents. In the future, resistin could become a significant clinical marker for evaluation of cardiometabolic risk., Uvod: Gojaznost u dečjem uzrastu se povezuje sa razvojem kardiovaskularnih bolesti i tipa 2 dijabetes melitusa u kasnijem dobu. Smatra se da je rezistin, adipokin kojeg u humanom organizumu luče monociti i tkivne makrofage, povezan sa ovim poremećajima. Cilj: Ispitati povezanost koncentracije rezistina kod gojazne dece i adolescenata sa antropometrijskim parametrima gojaznosti, lipidnim statusom, inflamatornim markerima i parametrima insulinske rezistencije. Materijal i metode: U istraživanju je učestvovalo 66 ispitanika (40 dečaka, 26 devojčica) kojima su izvršena antropometrijska merenja i laboratorijska ispitivanja (koncentracije glukoze, ukupnog holesterola, holesterola u česticama lipoproteina visoke gustine (eng. high-density lipoprotein, HDL) i niske gustine (eng. low-density lipoprotein, LDL), triglicerida, mokraćne kiseline, visokoosetljivog C-reaktivnog proteina (high-sensitivity C-reactive protein; hsCRP) i glikoziliranog hemoglobina (HbA1c)). Insulinska rezistencija je procenjena na osnovu modela za izračunavanje indeksa insulinske rezistencije (eng. homeostasis model assessment of insulin resistance; HOMA-IR). Rezultati: Kod 63,3% ispitanika utvrdili smo prisutnu dislipidemiju, a dobijene vrednosti hsCRP i mokraćne kiseline ukazuju na prisustvo inflamacije. Utvrdili smo korelaciju između koncentracije rezistina i odnosa obima struka i kukova (r=0,294, p lt 0,05) i između koncentracije rezistina i HOMA-IR (r=0,293, p lt 0,05). Ustanovili smo povezanost koncentracije mokraćne kiseline i parametara gojaznosti. Upoređivanjem parametara između polova, značajna razlika postoji u telesnoj visini (p lt 0,01), odnosu obima struka i kukova (p lt 0,001), mokraćnoj kiselini (p lt 0,01) i HOMA-IR (p lt 0,01). Zaključak: Naši rezultati ukazuju na povezanost gojaznosti, inflamacije i dislipidemije kod dece i adolescenata. Rezistin bi u budućnosti mogao biti značajan za procenu kardiometaboličkog rizika u ovoj populaciji.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Resistin, inflammation and dyslipidemia in obese children and adolescents, Rezistin, inflamacija i dislipidemija kod gojazne dece i adolescenata",
volume = "65",
number = "2",
pages = "115-128",
doi = "10.5937/arhfarm1502115P"
}

Pavlović, B., Milosavljević, J., Zeljković, A., Vekić, J., Joksić, J., Sopić, M., Spasojević-Kalimanovska, V., Paripović, D., Peco-Antić, A., Miloševski-Lomić, G.,& Jelić-Ivanović, Z.. (2015). Resistin, inflammation and dyslipidemia in obese children and adolescents. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 65(2), 115-128.
https://doi.org/10.5937/arhfarm1502115P

Pavlović B, Milosavljević J, Zeljković A, Vekić J, Joksić J, Sopić M, Spasojević-Kalimanovska V, Paripović D, Peco-Antić A, Miloševski-Lomić G, Jelić-Ivanović Z. Resistin, inflammation and dyslipidemia in obese children and adolescents. in Arhiv za farmaciju. 2015;65(2):115-128.
doi:10.5937/arhfarm1502115P .

Pavlović, Branko, Milosavljević, Jovana, Zeljković, Aleksandra, Vekić, Jelena, Joksić, Jelena, Sopić, Miron, Spasojević-Kalimanovska, Vesna, Paripović, Dušan, Peco-Antić, Amira, Miloševski-Lomić, Gordana, Jelić-Ivanović, Zorana, "Resistin, inflammation and dyslipidemia in obese children and adolescents" in Arhiv za farmaciju, 65, no. 2 (2015):115-128,
https://doi.org/10.5937/arhfarm1502115P . .

TY  - JOUR
AU  - Petrović, Stanislava
AU  - Bogavac-Stanojević, Nataša
AU  - Kotur-Stevuljević, Jelena
AU  - Peco-Antić, Amira
AU  - Ivanišević, Ivana
AU  - Ivanišević, Jasmina
AU  - Paripović, Dušan
AU  - Jelić-Ivanović, Zorana
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2195
AB  - Introduction: Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acute kidney injury (AKI) development. Materials and methods: The patients enrolled in the study comprised 50 Caucasian children (median age was 6 months) with UTI. Total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), inflammation marker C-reactive protein (CRP) and renal function parameters urea and creatinine were analyzed in patient's serums. Results: According to duration of inflammation during UTI, TAS values were significantly higher (0.99 vs. 0.58 mmol/L, P = 0.017) and OSI values were significantly lower (0.032 vs. 0.041 AU, P = 0.037) in the subjects with longer duration of inflammation than in the subjects with shorter duration of inflammation. We did not find significant difference in basal values of oxidative status parameters according to AKI development. Conclusions: OSI values could detect the simultaneous change of TAS and TOS due to change in the oxidative-antioxidant balance during the recovery of children with UTI. TAS and OSI as markers of oxidative stress during UTI are sensitive to accompanying inflammatory condition. Further investigations are needed to evaluate whether TAS, TOS and OSI could be used to monitor disease severity in children with UTI.
PB  - Croatian Soc Medical Biochemists, Zagreb
T2  - Biochemia Medica
T1  - Oxidative status parameters in children with urinary tract infection
VL  - 24
IS  - 2
SP  - 266
EP  - 272
DO  - 10.11613/BM.2014.029
ER  - 

@article{
author = "Petrović, Stanislava and Bogavac-Stanojević, Nataša and Kotur-Stevuljević, Jelena and Peco-Antić, Amira and Ivanišević, Ivana and Ivanišević, Jasmina and Paripović, Dušan and Jelić-Ivanović, Zorana",
year = "2014",
abstract = "Introduction: Urinary tract infection (UTI) is one of the most common bacterial infectious diseases in children. The aim of this study was to determine the total prooxidant and antioxidant capacity of children with UTI, as well as changes of oxidative status parameters according to acute inflammation persistence and acute kidney injury (AKI) development. Materials and methods: The patients enrolled in the study comprised 50 Caucasian children (median age was 6 months) with UTI. Total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), inflammation marker C-reactive protein (CRP) and renal function parameters urea and creatinine were analyzed in patient's serums. Results: According to duration of inflammation during UTI, TAS values were significantly higher (0.99 vs. 0.58 mmol/L, P = 0.017) and OSI values were significantly lower (0.032 vs. 0.041 AU, P = 0.037) in the subjects with longer duration of inflammation than in the subjects with shorter duration of inflammation. We did not find significant difference in basal values of oxidative status parameters according to AKI development. Conclusions: OSI values could detect the simultaneous change of TAS and TOS due to change in the oxidative-antioxidant balance during the recovery of children with UTI. TAS and OSI as markers of oxidative stress during UTI are sensitive to accompanying inflammatory condition. Further investigations are needed to evaluate whether TAS, TOS and OSI could be used to monitor disease severity in children with UTI.",
publisher = "Croatian Soc Medical Biochemists, Zagreb",
journal = "Biochemia Medica",
title = "Oxidative status parameters in children with urinary tract infection",
volume = "24",
number = "2",
pages = "266-272",
doi = "10.11613/BM.2014.029"
}

Petrović, S., Bogavac-Stanojević, N., Kotur-Stevuljević, J., Peco-Antić, A., Ivanišević, I., Ivanišević, J., Paripović, D.,& Jelić-Ivanović, Z.. (2014). Oxidative status parameters in children with urinary tract infection. in Biochemia Medica
Croatian Soc Medical Biochemists, Zagreb., 24(2), 266-272.
https://doi.org/10.11613/BM.2014.029

Petrović S, Bogavac-Stanojević N, Kotur-Stevuljević J, Peco-Antić A, Ivanišević I, Ivanišević J, Paripović D, Jelić-Ivanović Z. Oxidative status parameters in children with urinary tract infection. in Biochemia Medica. 2014;24(2):266-272.
doi:10.11613/BM.2014.029 .

Petrović, Stanislava, Bogavac-Stanojević, Nataša, Kotur-Stevuljević, Jelena, Peco-Antić, Amira, Ivanišević, Ivana, Ivanišević, Jasmina, Paripović, Dušan, Jelić-Ivanović, Zorana, "Oxidative status parameters in children with urinary tract infection" in Biochemia Medica, 24, no. 2 (2014):266-272,
https://doi.org/10.11613/BM.2014.029 . .

TY  - JOUR
AU  - Kotur-Stevuljević, Jelena
AU  - Peco-Antić, Amira
AU  - Spasić, Slavica
AU  - Stefanović, Aleksandra
AU  - Paripović, Dušan
AU  - Kostić, Mirjana
AU  - Vasić, Dragan
AU  - Vujović, Ana
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Kornić-Ristovski, Danijela
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1943
AB  - The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure of early atherosclerosis. Fifty-two pediatric CKD patients were enrolled in the study (10 with chronic renal failure [CRF], 22 with a renal transplant [RT], 20 with chronic hemodialysis (cHD) patients, and 36 healthy children (control group, CG). Lipid status, oxidative stress, and paraoxonase 1 (PON1) status were assessed. cIMT was measured by ultrasound, adjusted for age and sex, and presented as standard deviation scores (SDS). Children with CKD had disturbed lipid content, which was most pronounced in cHD children, with higher free cholesterol and triglycerides compared with healthy children. Oxidative stress was markedly increased (malodialdehyde [MDA, mu mol/L]: CRF 1.50 +/- 0.26, RT 1.55 +/- 0.40, cHD 1.77 +/- 0.34, CG 0.97 +/- 0.33, p  lt  0.001) and antioxidative defense was compromised (superoxide dismutase [SOD, U/L]: CG 120 +/- 21, CRF 84 +/- 25, RT 93 +/- 12, cHD 119 +/- 37, p  lt  0.001). Multiple linear regression analysis showed that a model that included disease duration, blood pressure, urea, lipid, and oxidative status parameters accounted for more than 90% of the variability of cIMT-SDS. Early atherosclerosis in CKD children is caused, at least in part, by dyslipidemia and oxidative stress. Monitoring of vessel wall changes, along with assessment of oxidative stress status and high density lipoprotein (HDL) functionality is necessary to ensure better therapeutic strategies for delaying atherosclerotic changes in their asymptomatic phase.
PB  - Springer, New York
T2  - Pediatric Nephrology
T1  - Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease
VL  - 28
IS  - 2
SP  - 295
EP  - 303
DO  - 10.1007/s00467-012-2323-5
ER  - 

@article{
author = "Kotur-Stevuljević, Jelena and Peco-Antić, Amira and Spasić, Slavica and Stefanović, Aleksandra and Paripović, Dušan and Kostić, Mirjana and Vasić, Dragan and Vujović, Ana and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Kornić-Ristovski, Danijela",
year = "2013",
abstract = "The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure of early atherosclerosis. Fifty-two pediatric CKD patients were enrolled in the study (10 with chronic renal failure [CRF], 22 with a renal transplant [RT], 20 with chronic hemodialysis (cHD) patients, and 36 healthy children (control group, CG). Lipid status, oxidative stress, and paraoxonase 1 (PON1) status were assessed. cIMT was measured by ultrasound, adjusted for age and sex, and presented as standard deviation scores (SDS). Children with CKD had disturbed lipid content, which was most pronounced in cHD children, with higher free cholesterol and triglycerides compared with healthy children. Oxidative stress was markedly increased (malodialdehyde [MDA, mu mol/L]: CRF 1.50 +/- 0.26, RT 1.55 +/- 0.40, cHD 1.77 +/- 0.34, CG 0.97 +/- 0.33, p  lt  0.001) and antioxidative defense was compromised (superoxide dismutase [SOD, U/L]: CG 120 +/- 21, CRF 84 +/- 25, RT 93 +/- 12, cHD 119 +/- 37, p  lt  0.001). Multiple linear regression analysis showed that a model that included disease duration, blood pressure, urea, lipid, and oxidative status parameters accounted for more than 90% of the variability of cIMT-SDS. Early atherosclerosis in CKD children is caused, at least in part, by dyslipidemia and oxidative stress. Monitoring of vessel wall changes, along with assessment of oxidative stress status and high density lipoprotein (HDL) functionality is necessary to ensure better therapeutic strategies for delaying atherosclerotic changes in their asymptomatic phase.",
publisher = "Springer, New York",
journal = "Pediatric Nephrology",
title = "Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease",
volume = "28",
number = "2",
pages = "295-303",
doi = "10.1007/s00467-012-2323-5"
}

Kotur-Stevuljević, J., Peco-Antić, A., Spasić, S., Stefanović, A., Paripović, D., Kostić, M., Vasić, D., Vujović, A., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V.,& Kornić-Ristovski, D.. (2013). Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease. in Pediatric Nephrology
Springer, New York., 28(2), 295-303.
https://doi.org/10.1007/s00467-012-2323-5

Kotur-Stevuljević J, Peco-Antić A, Spasić S, Stefanović A, Paripović D, Kostić M, Vasić D, Vujović A, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Kornić-Ristovski D. Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease. in Pediatric Nephrology. 2013;28(2):295-303.
doi:10.1007/s00467-012-2323-5 .

Kotur-Stevuljević, Jelena, Peco-Antić, Amira, Spasić, Slavica, Stefanović, Aleksandra, Paripović, Dušan, Kostić, Mirjana, Vasić, Dragan, Vujović, Ana, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Kornić-Ristovski, Danijela, "Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease" in Pediatric Nephrology, 28, no. 2 (2013):295-303,
https://doi.org/10.1007/s00467-012-2323-5 . .

TY  - JOUR
AU  - Petrović, Stanislava
AU  - Bogavac-Stanojević, Nataša
AU  - Peco-Antić, Amira
AU  - Ivanišević, Ivana
AU  - Kotur-Stevuljević, Jelena
AU  - Paripović, Dušan
AU  - Sopić, Miron
AU  - Jelić-Ivanović, Zorana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1971
AB  - Background. The aim of this study was to examine the novel renal biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) to assist pediatricians in the assessment of longer duration of inflammation and acute kidney injury (AKI) development during urinary tract infection (UTI). Methods. The patients enrolled in the study comprised 50 children (mean age was 6 months) with UTI. NGAL in serum and urine (sNGAL and uNGAL, resp.) and KIM-1 in urine were measured by enzyme-linked immunosorbent assays. Results. uNGAL levels in subjects with longer duration of inflammation were higher (115.37 ng/mL) than uNGAL levels in subjects with shorter duration of inflammation (67.87 ng/mL, P = 0.022). Difference in sNGAL and KIM-1 levels was not significant (P = 0.155 and P = 0.198, resp.). Significant difference was seen in KIM-1 excretion among groups with and without AKI (P = 0.038). KIM-1 was not able to discriminate between subjects with and without AKI (area under the curves (AUC) = 0.620, P = 0.175). Conclusions. uNGAL cannot be used for screening of the duration of inflammation during UTI. Accuracy of KIM-1 in screening of AKI development in children with UTI is low. We suggest larger studies to check the negative predictive value of KIM-1 for the development of AKI.
PB  - Hindawi Publishing Corporation, New York
T2  - Biomed Research International
T1  - Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection
DO  - 10.1155/2013/947157
ER  - 

@article{
author = "Petrović, Stanislava and Bogavac-Stanojević, Nataša and Peco-Antić, Amira and Ivanišević, Ivana and Kotur-Stevuljević, Jelena and Paripović, Dušan and Sopić, Miron and Jelić-Ivanović, Zorana",
year = "2013",
abstract = "Background. The aim of this study was to examine the novel renal biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) to assist pediatricians in the assessment of longer duration of inflammation and acute kidney injury (AKI) development during urinary tract infection (UTI). Methods. The patients enrolled in the study comprised 50 children (mean age was 6 months) with UTI. NGAL in serum and urine (sNGAL and uNGAL, resp.) and KIM-1 in urine were measured by enzyme-linked immunosorbent assays. Results. uNGAL levels in subjects with longer duration of inflammation were higher (115.37 ng/mL) than uNGAL levels in subjects with shorter duration of inflammation (67.87 ng/mL, P = 0.022). Difference in sNGAL and KIM-1 levels was not significant (P = 0.155 and P = 0.198, resp.). Significant difference was seen in KIM-1 excretion among groups with and without AKI (P = 0.038). KIM-1 was not able to discriminate between subjects with and without AKI (area under the curves (AUC) = 0.620, P = 0.175). Conclusions. uNGAL cannot be used for screening of the duration of inflammation during UTI. Accuracy of KIM-1 in screening of AKI development in children with UTI is low. We suggest larger studies to check the negative predictive value of KIM-1 for the development of AKI.",
publisher = "Hindawi Publishing Corporation, New York",
journal = "Biomed Research International",
title = "Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection",
doi = "10.1155/2013/947157"
}

Petrović, S., Bogavac-Stanojević, N., Peco-Antić, A., Ivanišević, I., Kotur-Stevuljević, J., Paripović, D., Sopić, M.,& Jelić-Ivanović, Z.. (2013). Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection. in Biomed Research International
Hindawi Publishing Corporation, New York..
https://doi.org/10.1155/2013/947157

Petrović S, Bogavac-Stanojević N, Peco-Antić A, Ivanišević I, Kotur-Stevuljević J, Paripović D, Sopić M, Jelić-Ivanović Z. Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection. in Biomed Research International. 2013;.
doi:10.1155/2013/947157 .

Petrović, Stanislava, Bogavac-Stanojević, Nataša, Peco-Antić, Amira, Ivanišević, Ivana, Kotur-Stevuljević, Jelena, Paripović, Dušan, Sopić, Miron, Jelić-Ivanović, Zorana, "Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection" in Biomed Research International (2013),
https://doi.org/10.1155/2013/947157 . .

TY  - JOUR
AU  - Peco-Antić, Amira
AU  - Paripović, Dušan
AU  - Kotur-Stevuljević, Jelena
AU  - Stefanović, Aleksandra
AU  - Scekić, Gordana
AU  - Miloševski-Lomić, Gordana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1625
AB  - Objective: The aim of the study was to investigate renal functional reserve (RFR) and to assess its relationship with serum cystatin C and blood pressure in children with apparently normal congenital solitary functioning kidney (SFK). Material and methods: RFR was obtained from the difference of endogenous creatinine clearance (CrCs) before and after a meat-free oral protein load (OPL) in the patients who were pre-treated with cimetidine. Serum cystatin C and urinary protein excretion were determined before and after OPL Results: Among 22 patients (13 boys), aged 9.5 +/- 4.3years, 72.7% had increased serum cystatin C, and 54.5% had decreased RFR. Following OPL, CrCs and urine creatinine increased, while serum creatinine and cystatin C remained unchanged. The multiple regression analysis demonstrated that cystatin C could predict more than 90% of RFR variability. Conclusion: Half of the patients with apparently normal SFK had decreased RFR. Serum cystatin C is one of the best predictors of RFR.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Clinical Biochemistry
T1  - Renal functional reserve in children with apparently normal congenital solitary functioning kidney
VL  - 45
IS  - 15
SP  - 1173
EP  - 1177
DO  - 10.1016/j.clinbiochem.2012.06.018
ER  - 

@article{
author = "Peco-Antić, Amira and Paripović, Dušan and Kotur-Stevuljević, Jelena and Stefanović, Aleksandra and Scekić, Gordana and Miloševski-Lomić, Gordana",
year = "2012",
abstract = "Objective: The aim of the study was to investigate renal functional reserve (RFR) and to assess its relationship with serum cystatin C and blood pressure in children with apparently normal congenital solitary functioning kidney (SFK). Material and methods: RFR was obtained from the difference of endogenous creatinine clearance (CrCs) before and after a meat-free oral protein load (OPL) in the patients who were pre-treated with cimetidine. Serum cystatin C and urinary protein excretion were determined before and after OPL Results: Among 22 patients (13 boys), aged 9.5 +/- 4.3years, 72.7% had increased serum cystatin C, and 54.5% had decreased RFR. Following OPL, CrCs and urine creatinine increased, while serum creatinine and cystatin C remained unchanged. The multiple regression analysis demonstrated that cystatin C could predict more than 90% of RFR variability. Conclusion: Half of the patients with apparently normal SFK had decreased RFR. Serum cystatin C is one of the best predictors of RFR.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Clinical Biochemistry",
title = "Renal functional reserve in children with apparently normal congenital solitary functioning kidney",
volume = "45",
number = "15",
pages = "1173-1177",
doi = "10.1016/j.clinbiochem.2012.06.018"
}

Peco-Antić, A., Paripović, D., Kotur-Stevuljević, J., Stefanović, A., Scekić, G.,& Miloševski-Lomić, G.. (2012). Renal functional reserve in children with apparently normal congenital solitary functioning kidney. in Clinical Biochemistry
Pergamon-Elsevier Science Ltd, Oxford., 45(15), 1173-1177.
https://doi.org/10.1016/j.clinbiochem.2012.06.018

Peco-Antić A, Paripović D, Kotur-Stevuljević J, Stefanović A, Scekić G, Miloševski-Lomić G. Renal functional reserve in children with apparently normal congenital solitary functioning kidney. in Clinical Biochemistry. 2012;45(15):1173-1177.
doi:10.1016/j.clinbiochem.2012.06.018 .

Peco-Antić, Amira, Paripović, Dušan, Kotur-Stevuljević, Jelena, Stefanović, Aleksandra, Scekić, Gordana, Miloševski-Lomić, Gordana, "Renal functional reserve in children with apparently normal congenital solitary functioning kidney" in Clinical Biochemistry, 45, no. 15 (2012):1173-1177,
https://doi.org/10.1016/j.clinbiochem.2012.06.018 . .

TY  - CONF
AU  - Peco-Antić, Amira
AU  - Kotur-Stevuljević, Jelena
AU  - Paripović, Dušan
AU  - Scekić, Gordana
AU  - Miloševski-Lomić, Gordana
AU  - Bogićević, Dragana
AU  - Spasojević-Dimitrijeva, Brankica
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1678
PB  - Oxford Univ Press, Oxford
C3  - Nephrology Dialysis Transplantation
T1  - Renal functional reserve in children with solitary kidney and chronic renal failure
VL  - 27
SP  - 546
EP  - 546
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1678
ER  - 

@conference{
author = "Peco-Antić, Amira and Kotur-Stevuljević, Jelena and Paripović, Dušan and Scekić, Gordana and Miloševski-Lomić, Gordana and Bogićević, Dragana and Spasojević-Dimitrijeva, Brankica",
year = "2012",
publisher = "Oxford Univ Press, Oxford",
journal = "Nephrology Dialysis Transplantation",
title = "Renal functional reserve in children with solitary kidney and chronic renal failure",
volume = "27",
pages = "546-546",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1678"
}

Peco-Antić, A., Kotur-Stevuljević, J., Paripović, D., Scekić, G., Miloševski-Lomić, G., Bogićević, D.,& Spasojević-Dimitrijeva, B.. (2012). Renal functional reserve in children with solitary kidney and chronic renal failure. in Nephrology Dialysis Transplantation
Oxford Univ Press, Oxford., 27, 546-546.
https://hdl.handle.net/21.15107/rcub_farfar_1678

Peco-Antić A, Kotur-Stevuljević J, Paripović D, Scekić G, Miloševski-Lomić G, Bogićević D, Spasojević-Dimitrijeva B. Renal functional reserve in children with solitary kidney and chronic renal failure. in Nephrology Dialysis Transplantation. 2012;27:546-546.
https://hdl.handle.net/21.15107/rcub_farfar_1678 .

Peco-Antić, Amira, Kotur-Stevuljević, Jelena, Paripović, Dušan, Scekić, Gordana, Miloševski-Lomić, Gordana, Bogićević, Dragana, Spasojević-Dimitrijeva, Brankica, "Renal functional reserve in children with solitary kidney and chronic renal failure" in Nephrology Dialysis Transplantation, 27 (2012):546-546,
https://hdl.handle.net/21.15107/rcub_farfar_1678 .